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List of works by Stefan Schreiber

15q13.3 microdeletions increase risk of idiopathic generalized epilepsy

scientific article

A Nonsynonymous SNP in ATG16L1 Predisposes to Ileal Crohn’s Disease and Is Independent of CARD15 and IBD5

scientific article

A case-only study of gene-environment interaction between genetic susceptibility variants in NOD2 and cigarette smoking in Crohn's disease aetiology.

scientific article

A common functional exon polymorphism in the microsomal triglyceride transfer protein gene is associated with type 2 diabetes, impaired glucose metabolism and insulin levels

scientific article

A common haplotype of the annexin A5 (ANXA5) gene promoter is associated with recurrent pregnancy loss

scientific article

A common variant on chromosome 11q13 is associated with atopic dermatitis

scientific article published on 6 April 2009

A comparison of oligonucleotide and cDNA-based microarray systems

scientific article published on 13 February 2004

A comprehensive analysis of the COL29A1 gene does not support a role in eczema

scientific article published on 25 February 2011

A comprehensive evaluation of SNP genotype imputation

scientific article

A comprehensively molecular haplotype-resolved genome of a European individual

scientific article

A functional EXO1 promoter variant is associated with prolonged life expectancy in centenarians

scientific article published on 19 August 2009

A functional haplotype in the 3'untranslated region of TNFRSF1B is associated with tuberculosis in two African populations

scientific article

A functional methylome map of ulcerative colitis

scientific article

A functional promotor polymorphism of TNF-alpha is associated with primary gastric B-Cell lymphoma.

scientific article

A genome-wide analysis of populations from European Russia reveals a new pole of genetic diversity in northern Europe

scientific article published in 2013

A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease

scientific article published on 15 July 2007

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

scientific article (publication date: February 2007)

A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

scientific article published on 19 October 2015

A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex

scientific article published on 7 February 2012

A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy

scientific article published on 12 July 2013

A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis

scientific journal article

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease

scientific article

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

article

A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis

scientific article published on 16 January 2018

A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis

scientific article published on 25 April 2017

A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation

scientific article

A genome-wide linkage analysis in 181 German sarcoidosis families using clustered biallelic markers.

scientific article published on 26 February 2010

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

scientific article

A haplotype block downstream of plasminogen is associated with chronic and aggressive periodontitis

scientific article published on 26 May 2017

A large candidate-gene association study suggests genetic variants at IRF5 and PRDM1 to be associated with aggressive periodontitis

scientific article published on 15 November 2014

A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level

scientific article

A multicenter, randomized, double-blind trial of everolimus versus azathioprine and placebo to maintain steroid-induced remission in patients with moderate-to-severe active Crohn's disease

scientific article published on 30 July 2008

A novel sarcoidosis risk locus for Europeans on chromosome 11q13.1

scientific article

A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis ⬇️

scientific article published on June 20, 2012

A randomised placebo-controlled multicentre trial of intravenous semapimod HCl for moderate to severe Crohn's disease

scientific article published in June 2010

A randomized controlled trial of the efficacy and safety of CCX282-B, an orally-administered blocker of chemokine receptor CCR9, for patients with Crohn's disease

scientific article

A randomized, placebo-controlled trial of certolizumab pegol (CDP870) for treatment of Crohn's disease

scientific article

A role for membrane-bound CD147 in NOD2-mediated recognition of bacterial cytoinvasion

scientific article published on February 2008

A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways

scholarly article

A tissue-specific landscape of sense/antisense transcription in the mouse intestine

scientific article

A two-step association study identifies CAV2 rs2270188 single nucleotide polymorphism interaction with fat intake in type 2 diabetes risk

scientific article published on 22 December 2010

A variant in the heart-specific fatty acid transport protein 6 is associated with lower fasting and postprandial TAG, blood pressure and left ventricular hypertrophy ⬇️

scientific article published on September 16, 2011

ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation

scientific journal article

AKT1 fails to replicate as a longevity-associated gene in Danish and German nonagenarians and centenarians

scientific article published on 29 August 2012

APOEε4is associated with higher vitamin D levels in targeted replacement mice and humans ⬇️

scientific article (publication date: September 2011)

Abatacept for Crohn's Disease and Ulcerative Colitis ⬇️

scientific article published on April 12, 2012

Abdominal malrotation overlooked at extensive cross-sectional imaging and leading to life-threatening gastrointestinal bleeding

scientific article published on 29 December 2015

Ablation of gly96/immediate early gene-X1 (gly96/iex-1) aggravates DSS-induced colitis in mice: role for gly96/iex-1 in the regulation of NF-kappaB.

scientific article published on February 2010

Accurate variant detection across non-amplified and whole genome amplified DNA using targeted next generation sequencing

scientific article

Activation of NF-kappaB in intestinal epithelial cells by E. coli strains isolated from the colonic mucosa of IBD patients

scientific article

Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: the CHARM trial

scientific article

Adjustment for smoking does not alter the FOXO3A association with longevity

scientific article

Allelic and copy-number variations of FcγRs affect granulocyte function and susceptibility for autoimmune blistering diseases

scientific article published on 29 May 2015

Allelic variation and human longevity

scientific article

Allelic variation in BTNL2 and susceptibility to tuberculosis in a South African population

scientific article

Allelic variation in the CNDP1 gene and its lack of association with longevity and coronary heart disease

scientific article

Alterations of pre-mRNA splicing in human inflammatory bowel disease

article

American gastroenterological association consensus development conference on the use of biologics in the treatment of inflammatory bowel disease, June 21-23, 2006.

scientific article published on July 2007

An evaluation of the genetic-matched pair study design using genome-wide SNP data from the European population

scientific article

Analysis of NOD2-mediated proteome response to muramyl dipeptide in HEK293 cells

scientific article published on 28 October 2005

Analysis of eight genes modulating interferon gamma and human genetic susceptibility to tuberculosis: a case-control association study

scientific article

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

scientific article

Analysis of relative gene dosage and expression differences of the paralogs RABL2A and RABL2B by Pyrosequencing

scientific article published on 04 February 2010

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans.

scientific article

Anti-IL-6 treatment for inflammatory bowel diseases: next cytokine, next target.

scientific article

Are bronchoalveolar lavages a good source for microbial profiling? Differences between throat and bronchoalveolar lavage microbiomes

scientific article

Are postoperative complications genetically determined by TNF-beta NcoI gene polymorphism?

scientific article published in April 2004

Assessing the fraction of short-distance tandem splice sites under purifying selection

scientific article published on 11 February 2008

Association Between Response to Etrolizumab and Expression of Integrin αE and Granzyme A in Colon Biopsies of Patients With Ulcerative Colitis

scientific article published on 29 October 2015

Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies

scientific article published on 25 April 2013

Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells

scientific article published on 20 April 2015

Association of FOXO3A variation with human longevity confirmed in German centenarians

scientific article

Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study

scientific article

Association of TH01 with human longevity revisited.

scientific article

Association of inflammatory bowel disease with indicators for childhood antigen and infection exposure

scientific article published on 10 April 2003

Association of postprandial and fasting triglycerides with traits of the metabolic syndrome in the Metabolic Intervention Cohort Kiel.

scientific article published on 14 January 2010

Association of prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism with type 2 diabetes in two German study populations

scientific article

Association study identifying polymorphisms in CD47 and other extracellular matrix pathway genes as putative prognostic markers for colorectal cancer

scientific article published on 28 July 2012

Association study of TRPC4 as a candidate gene for generalized epilepsy with photosensitivity.

scientific article

Atopobium and Fusobacterium as novel candidates for sarcoidosis-associated microbiota

scientific article published on 14 December 2017

Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity

scientific article published on 09 March 2022

B Lymphocyte Stimulator (BLyS) is expressed in human adipocytes in vivo and is related to obesity but not to insulin resistance

scientific article

Beneficial Effects of a Dietary Weight Loss Intervention on Human Gut Microbiome Diversity and Metabolism Are Not Sustained during Weight Maintenance

scientific article published on 30 November 2016

Biosimilar infliximab for inflammatory bowel disease: from concepts to clinical practice. Case study illustrated with CT-P13.

scientific article published on September 2015

Biosimilars in Inflammatory Bowel Disease (IBD): Experiences and perceptions of german gastroenterologists

scientific article published on 5 January 2017

Biosimilars in Inflammatory Bowel Disease: Facts and Fears of Extrapolation

scientific article

Broad consent for health care-embedded biobanking: understanding and reasons to donate in a large patient sample

scientific article published on 22 June 2017

CDKN2BAS is associated with periodontitis in different European populations and is activated by bacterial infection.

scientific article

CNVineta: a data mining tool for large case-control copy number variation datasets

scientific article

CT-P13 (Inflectra™, Remsima™) monitoring in patients with inflammatory bowel disease

scientific article published on 16 July 2016

CXC and CC chemokine expression in inflamed and noninflamed pelvic ileal pouch tissue.

scientific article

Can Zipf's law be adapted to normalize microarrays?

scientific article

Candidate gene association study of type 2 diabetes in a nested case-control study of the EPIC-Potsdam cohort - role of fat assimilation

scientific article

Candidate gene study of FOXO1, FOXO4, and FOXO6 reveals no association with human longevity in Germans ⬇️

scientific article published on April 12, 2011

Caspase recruitment domain-containing protein 8 (CARD8) negatively regulates NOD2-mediated signaling

scientific article published on 12 April 2010

Certolizumab pegol for active Crohn's disease: a placebo-controlled, randomized trial

scientific article

Certolizumab pegol for the treatment of Crohn's disease

scientific article (publication date: 19 July 2007)

Certolizumab pegol, a monthly subcutaneously administered Fc-free anti-TNFalpha, improves health-related quality of life in patients with moderate to severe Crohn's disease

scientific article

Characteristic changes in microbial community composition and expression of innate immune genes in acute appendicitis.

scientific article

Characterization of changes in serum anti-glycan antibodies in Crohn's disease--a longitudinal analysis

scientific article (publication date: 6 May 2011)

Chromosome 7p11.2 (EGFR) variation influences glioma risk

scientific journal article

Chronic portal vein thrombosis: transcapsular hepatic collateral vessels and communicating ectopic varices

scientific article published on 09 September 2010

Clinical remission in patients with moderate-to-severe Crohn's disease treated with filgotinib (the FITZROY study): results from a phase 2, double-blind, randomised, placebo-controlled trial.

scientific article published on 14 December 2016

Clinically meaningful improvement in health-related quality of life in a randomized controlled trial of certolizumab pegol maintenance therapy for Crohn's disease

scientific article

Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype

scientific article published on 8 November 2011

Combination therapy with vedolizumab and etanercept in a patient with pouchitis and spondylarthritis

scientific article published on 8 February 2017

Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci

scientific journal article

Common obesity risk alleles in childhood attention-deficit/hyperactivity disorder.

scientific article published on 26 March 2013

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

scientific article (publication date: May 2011)

Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From Patients

scientific article published on 15 June 2016

Compound heterozygous mutations in IL10RA combined with a complement factor properdin mutation in infantile-onset inflammatory bowel disease

scientific article published on 01 December 2018

Comprehensive assessment of sequence variation within the copy number variable defensin cluster on 8p23 by target enriched in-depth 454 sequencing

scientific article

Concentration of circulating miRNA-containing particles in serum enhances miRNA detection and reflects CRC tissue-related deregulations.

scientific article published on 23 September 2016

Concordance of genetic risk across migraine subgroups: Impact on current and future genetic association studies

scientific article published on September 2014

Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort

scientific article published on 27 January 2009

Constant splice-isoform ratios in human lymphoblastoid cells support the concept of a splico-stat

scientific article

Copy number variation in patients with cervical artery dissection ⬇️

scientific article published on May 23, 2012

Correction: Genetic Structure of Europeans: A View from the North–East.

scientific article

Correction: Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study.

scientific article

Correlation between genetic and geographic structure in Europe

scientific article

Correlation between the Crohn's disease activity and Harvey-Bradshaw indices in assessing Crohn's disease severity

scientific article published on 21 January 2010

Corticosteroids and immunosuppressive therapy influence the result of QuantiFERON TB Gold testing in inflammatory bowel disease patients ⬇️

scientific article published on October 19, 2011

Cost-effectiveness of biological treatment sequences for fistulising Crohn's disease across Europe

scientific article published on 8 May 2017

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

scientific article

Current software for genotype imputation

scientific article

DMBT1 functions as pattern-recognition molecule for poly-sulfated and poly-phosphorylated ligands

scientific article

DNA methylation analysis in nonalcoholic fatty liver disease suggests distinct disease-specific and remodeling signatures after bariatric surgery

scientific article published on August 2013

DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses

scientific article published on October 2009

Deciphering the 8q24.21 association for glioma

scientific article published on 11 February 2013

Decreased sigmoidal ABCB1 (P-glycoprotein) expression in ulcerative colitis is associated with disease activity.

scientific article

Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis

scientific article

Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma

scientific article

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.

scientific article

Depletion of potential A2M risk haplotype for Alzheimer's disease in long-lived individuals

scientific article

Detection of diverse bacterial signatures in atherosclerotic lesions of patients with coronary heart disease

scientific article published in February 2006

Development and validation of the Nancy histological index for UC.

scientific article published on 13 October 2015

Development of an index to define overall disease severity in IBD.

scientific article published on 25 October 2016

Development of the Crohn's disease digestive damage score, the Lémann score

scientific article published on 28 November 2010

Development of the Lémann index to assess digestive tract damage in patients with Crohn's disease.

scientific article published on 21 September 2014

Development of the Paris definition of early Crohn's disease for disease-modification trials: results of an international expert opinion process

scientific article published on December 2012

Diagnosing fatty liver disease: a comparative evaluation of metabolic markers, phenotypes, genotypes and established biomarkers

scientific article

Diagnostics of inflammatory bowel disease

scientific article published on November 2007

Disruption at the PTCHD1 Locus on Xp22.11 in Autism spectrum disorder and intellectual disability

scientific article

Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays

scientific article

Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota.

scientific article published on 29 June 2015

Dopamine receptor D3 gene and essential tremor in large series of German, Danish and French patients

scientific article

Dosage adjustment during long-term adalimumab treatment for Crohnʼs disease: Clinical efficacy and pharmacoeconomics ⬇️

scientific article published on January 1, 2011

Dynamic changes of the luminal and mucosa-associated gut microbiota during and after antibiotic therapy with paromomycin

scientific article published on July 2015

Dynamics of the mucosa-associated flora in ulcerative colitis patients during remission and clinical relapse

scientific article

Dysfunctional nitric oxide signalling increases risk of myocardial infarction

scientific article published on 10 November 2013

Early remission status predicts long-term outcomes in patients with Crohn's disease treated with certolizumab pegol

scientific article published on 5 August 2016

Early-onset Crohn's disease and autoimmunity associated with a variant in CTLA-4

scientific article

Effect of Lactobacillus gasseri PA 16/8, Bifidobacterium longum SP 07/3, B. bifidum MF 20/5 on common cold episodes: a double blind, randomized, controlled trial.

scientific article

Effect of extended MMX mesalamine therapy for acute, mild-to-moderate ulcerative colitis

scientific article published in January 2009

Effect of tight control management on Crohn's disease (CALM): a multicentre, randomised, controlled phase 3 trial

scientific article published on 30 October 2017

Effects of Transient and Persistent Anti-drug Antibodies to Certolizumab Pegol: Longitudinal Data from a 7-Year Study in Crohn's Disease

scientific article

Effects of adalimumab therapy on incidence of hospitalization and surgery in Crohn's disease: results from the CHARM study

scientific article

Effects of probiotics and antibiotics on the intestinal homeostasis in a computer controlled model of the large intestine

scientific article

Effects of β-lactam antibiotics and fluoroquinolones on human gut microbiota in relation to Clostridium difficile associated diarrhea

scientific article

Efficacy assessment of SNP sets for genome-wide disease association studies

scientific article

Efficacy of Sterile Fecal Filtrate Transfer for Treating Patients With Clostridium difficile Infection.

scientific article

Emerging genetic patterns of the European Neolithic: perspectives from a late Neolithic Bell Beaker burial site in Germany

scientific article published in August 2012

Entropy-based SNP selection for genetic association studies ⬇️

scientific article published on September 18, 2003

Epidemiology of inflammatory bowel disease in a German twin cohort: results of a nationwide study

scientific article published in July 2008

Epigenetics of Inflammatory Bowel Disease

article

Epithelial IL-23R Signaling Licenses Protective IL-22 Responses in Intestinal Inflammation

scientific article

Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice

scientific article published on 28 September 2018

Epithelial calcineurin controls microbiota-dependent intestinal tumor development

scientific article published on 4 April 2016

Erratum: Corrigendum: Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis

scholarly article published in Nature Genetics

Erratum: Corrigendum: Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scholarly article published in Nature Genetics

Erratum: Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

scientific article published in October 2016

Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial

scientific article published on 9 May 2014

Evaluation of interleukin-6 and its soluble receptor components sIL-6R and sgp130 as markers of inflammation in inflammatory bowel diseases.

scientific article

Evaluation of the Cross-reactivity of Antidrug Antibodies to CT-P13 and Infliximab Reference Product (Remicade): An Analysis Using Immunoassays Tagged with Both Agents

scientific article

Evidence for a NOD2-independent susceptibility locus for inflammatory bowel disease on chromosome 16p.

scientific article

Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity

scientific article published on 12 January 2012

Evolution and function of innate immune receptors--insights from marine invertebrates

scientific article published on 02 April 2009

Exon-disrupting deletions of NRXN1 in idiopathic generalized epilepsy

scientific article published on 7 January 2013

Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development.

scientific article published on 13 April 2018

Expression signatures, barriers and beyond: the role of oxidative stress in murine colitis and human inflammatory bowel disease revisited

scientific article published on June 2008

Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci

scientific article

Extracellular cathepsin K exerts antimicrobial activity and is protective against chronic intestinal inflammation in mice

scientific article published on 22 March 2012

FTO genotype is associated with phenotypic variability of body mass index

scientific article published on 16 September 2012

Family-Based Benchmarking of Copy Number Variation Detection Software

scientific article published on 21 July 2015

Female-specific association of C-C chemokine receptor 5 gene polymorphisms with Löfgren's syndrome

scientific article published in March 2008

First multicenter study of modified release phosphatidylcholine "LT-02" in ulcerative colitis: a randomized, placebo-controlled trial in mesalazine-refractory courses

scientific article

From next-generation sequencing alignments to accurate comparison and validation of single-nucleotide variants: the pibase software

scientific article published on 10 September 2012

Functional characterization of two novel 5' untranslated exons reveals a complex regulation of NOD2 protein expression

scientific article

Fungal rDNA signatures in coronary atherosclerotic plaques

scientific article

Fungi and inflammatory bowel diseases: Alterations of composition and diversity

scientific article

G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation

scientific article published on 16 November 2009

GENOMIZER: an integrated analysis system for genome-wide association data

scientific article

GMFilter and SXTestPlate: software tools for improving the SNPlex genotyping system

scientific article

Gene expression and physiological changes of different populations of the long-lived bivalve Arctica islandica under low oxygen conditions

scientific article published in 2012

Gene expression profiling of head and neck squamous cell carcinoma using cDNA microarrays.

scientific article

Gene-based pleiotropy across migraine with aura and migraine without aura patient groups

scientific article published on 8 December 2015

Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis

scientific article

Genetic Imbalance in Patients with Cervical Artery Dissection

scientific article

Genetic Variants in Matrix Metalloproteinase Genes Are Associated With Development of Gastric Ulcer in H. Pylori Infection

scientific article published on 01 January 2006

Genetic and functional identification of the likely causative variant for cholesterol gallstone disease at the ABCG5/8 lithogenic locus

scientific article published on 25 January 2013

Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis

scientific article published on 4 August 2017

Genetic characterization of northeastern Italian population isolates in the context of broader European genetic diversity

scientific article

Genetic control of global gene expression levels in the intestinal mucosa: a human twin study

scientific article published on 10 March 2009

Genetic determinants of circulating sphingolipid concentrations in European populations

scientific article published on 02 October 2009

Genetic diversity of the obligate intracellular bacterium Chlamydophila pneumoniae by genome-wide analysis of single nucleotide polymorphisms: evidence for highly clonal population structure

scientific article

Genetic evidence for PLASMINOGEN as a shared genetic risk factor of coronary artery disease and periodontitis

scientific article published on 2 December 2014

Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease.

scientific article

Genetic interplay between human longevity and metabolic pathways - a large-scale eQTL study

scientific article published on 19 April 2017

Genetic investigation of FOXO3A requires special attention due to sequence homology with FOXO3B

scientific article published on 16 May 2012

Genetic regulation of serum phytosterol levels and risk of coronary artery disease

scientific article

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

scientific article

Genetic risk profiling and prediction of disease course in Crohn's disease patients

scientific article

Genetic structure of Europeans: a view from the North-East

scientific article

Genetic variants of the copy number polymorphic beta-defensin locus are associated with sporadic prostate cancer

scientific article

Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease

scientific article published on 8 July 2009

Genetic variation in DLG5 is associated with inflammatory bowel disease

scientific article

Genetic variation in the human androgen receptor gene is the major determinant of common early-onset androgenetic alopecia

scientific article

Genetically determined height and coronary artery disease

scientific article

Genetics of Crohn disease, an archetypal inflammatory barrier disease

scientific article

Genetics of healthy aging in Europe: the EU-integrated project GEHA (GEnetics of Healthy Aging).

scientific article published on April 2007

Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms.

scientific article published on 3 December 2015

Genome-wide analysis associates familial colorectal cancer with increases in copy number variations and a rare structural variation at 12p12.3.

scientific article published on 14 October 2013

Genome-wide analysis of single nucleotide polymorphisms uncovers population structure in Northern Europe

scientific article (publication date: 2008)

Genome-wide association analysis and fine mapping of NT-proBNP level provide novel insight into the role of the MTHFR-CLCN6-NPPA-NPPB gene cluster

scientific article

Genome-wide association analysis for chronic venous disease identifies EFEMP1 and KCNH8 as susceptibility loci

scientific article published on 04 April 2017

Genome-wide association analysis in primary sclerosing cholangitis

scientific article

Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4

scientific journal article

Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci

scientific journal article

Genome-wide association analysis in sarcoidosis and Crohn's disease unravels a common susceptibility locus on 10p12.2.

scientific article

Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis

scientific journal article

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

scientific article

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

scientific article

Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.

scientific article published on 30 March 2008

Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci

scientific article

Genome-wide association study for colorectal cancer identifies risk polymorphisms in German familial cases and implicates MAPK signalling pathways in disease susceptibility.

scientific article

Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).

scientific article

Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis

scientific article

Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis

scientific article

Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

scientific article

Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder

scientific article

Genome-wide association study identifies multiple susceptibility loci for glioma ⬇️

scientific article

Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate

scientific article

Genome-wide association study in German patients with attention deficit/hyperactivity disorder

scientific article published on 19 October 2011

Genome-wide association study in musician's dystonia: a risk variant at the arylsulfatase G locus?

scientific article published on 26 December 2013

Genome-wide association study of alcohol dependence

scientific journal article

Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors

scientific article published on 27 March 2017

Genome-wide association study of intracranial aneurysm identifies three new risk loci

scientific article

Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1.

scientific article

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

scientific article

Genome-wide association study reveals genetic risk underlying Parkinson's disease

scientific article

Genome-wide association-, replication-, and neuroimaging study implicates HOMER1 in the etiology of major depression

scientific article

Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms

scientific article

Genome-wide copy number variation in epilepsy: novel susceptibility loci in idiopathic generalized and focal epilepsies

scientific article

Genome-wide expression profiling identifies an impairment of negative feedback signals in the Crohn's disease-associated NOD2 variant L1007fsinsC.

scientific article published on 18 February 2011

Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease

scientific article published on 8 February 2009

Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

scientific article published on 06 February 2013

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis identifies new susceptibility loci for migraine

scientific article

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

scientific article

Genome-wide meta-analysis of common variant differences between men and women

scientific article published on 27 July 2012

Genome-wide meta-analysis of psoriatic arthritis identifies susceptibility locus at REL

scientific journal article

Genome-wide miRNA signatures of human longevity.

scientific article published on 30 May 2012

Genome-wide rare copy number variation screening in ulcerative colitis identifies potential susceptibility loci.

scientific article

Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways

scientific article

Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting

scientific article

Genomic landscape of positive natural selection in Northern European populations

scientific article

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options

scientific article

Geographical patterns of the standing and active human gut microbiome in health and IBD.

scientific article published on 7 January 2015

Germline variations of the MALT1 gene as risk factors in the development of primary gastric B-cell lymphoma

scientific article published on 24 April 2009

HBEGF, SRA1, and IK: Three cosegregating genes as determinants of cardiomyopathy

scientific article published on 08 December 2008

HLX1 gene variants influence the development of childhood asthma

scientific article published on 28 November 2008

Halophilic archaea in the human intestinal mucosa

scientific article published on 23 April 2010

Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnically divergent populations.

scientific article published in January 2003

Haplotype synthesis analysis reveals functional variants underlying known genome-wide associated susceptibility loci

scientific article published on 21 March 2016

Haplotyping and copy number estimation of the highly polymorphic human beta-defensin locus on 8p23 by 454 amplicon sequencing

scientific article

Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity

scientific article

Heritability of chronic venous disease

scientific article

High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.

scientific article published on 10 December 2015

High-density genotyping study identifies four new susceptibility loci for atopic dermatitis

scientific article published on 02 June 2013

High-resolution SNP scan of chromosome 6p21 in pooled samples from patients with complex diseases

scientific article

High-resolution mapping of the 8p23.1 beta-defensin cluster reveals strictly concordant copy number variation of all genes.

scientific article published in October 2008

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

scientific article

Human intestinal fatty acid binding protein 2 expression is associated with fat intake and polymorphisms

article

Human longevity and 11p15.5: a study in 1321 centenarians

scientific article

Human longevity and variation in DNA damage response and repair: study of the contribution of sub-processes using competitive gene-set analysis

scientific article

Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies

scientific article

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Hypothalamic Inflammation in Human Obesity Is Mediated by Environmental and Genetic Factors.

scientific article published on 2 June 2017

IBD5 is a general risk factor for inflammatory bowel disease: replication of association with Crohn disease and identification of a novel association with ulcerative colitis

scientific article

IEX-1 directly interferes with RelA/p65 dependent transactivation and regulation of apoptosis

scientific article

IL-1β and ADAM17 are central regulators of β-defensin expression in Candida esophagitis

scientific article published on 13 January 2011

IL-6 blockade by monoclonal antibodies inhibits apolipoprotein (a) expression and lipoprotein (a) synthesis in humans

scientific article published on 21 February 2015

Identification and characterization of two functional variants in the human longevity gene FOXO3.

scientific article published on 12 December 2017

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.

scientific article

Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk

scientific article

Identification of a shared genetic susceptibility locus for coronary heart disease and periodontitis

scientific article

Identification of mammalian orthologs associates PYPAF5 with distinct functional roles

scientific article

Identification, evolution, and association study of a novel promoter and first exon of the human NOD2 (CARD15) gene.

scientific article

Immunochip analysis identifies association of the RAD50/IL13 region with human longevity

scientific article published on 22 March 2016

Implementing changes in clinical practice to improve the management of Crohn's disease

scientific article

Improving mapping and SNP-calling performance in multiplexed targeted next-generation sequencing

scientific article

In vitro alterations of intestinal bacterial microbiota in fecal samples during storage.

scientific article published in December 2004

InSNP: a tool for automated detection and visualization of SNPs and InDels

scientific article

Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases

scientific article

Increased intestinal permeability and tight junction disruption by altered expression and localization of occludin in a murine graft versus host disease model

scientific article published on 06 October 2011

Increased response and remission rates in short-duration Crohn's disease with subcutaneous certolizumab pegol: an analysis of PRECiSE 2 randomized maintenance trial data

scientific article

Induction therapy with the selective interleukin-23 inhibitor risankizumab in patients with moderate-to-severe Crohn's disease: a randomised, double-blind, placebo-controlled phase 2 study

scientific article published on 12 April 2017

Inflammatory Bowel Disease Competence Network

scientific article published on 11 March 2016

Influence of IL-1 gene cluster polymorphisms on the development of H. pylori associated gastric ulcer

scientific article

Influence of polymorphisms in the NOD1/CARD4 and NOD2/CARD15 genes on the clinical outcome of Helicobacter pylori infection

scientific article published on July 2006

Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.

scientific article

Interpreting Registrational Clinical Trials of Biological Therapies in Adults with Inflammatory Bowel Diseases

scientific article

Interpreting whole genome and exome sequencing data of individual gastric cancer samples.

scientific article

Intestinal TM7 bacterial phylogenies in active inflammatory bowel disease

scientific article

Investigation of association of the DLG5 gene with phenotypes of inflammatory bowel disease in the British population

scientific article published on 31 May 2006

Investigation of chromosome 17 candidate genes in susceptibility to TB in a South African population

scientific article published on 14 January 2009

Investigation of complement component C4 copy number variation in human longevity

scientific article published on 22 January 2014

Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study

scientific article

Investigation of innate immunity genes CARD4, CARD8 and CARD15 as germline susceptibility factors for colorectal cancer

scientific article

Investigation of the Lith1 candidate genes ABCB11 and LXRA in human gallstone disease.

scientific article published in September 2006

Investigation of the Lith6 candidate genes APOBEC1 and PPARG in human gallstone disease

scientific article published in September 2007

Investigation of the fine structure of European populations with applications to disease association studies

scientific article published in December 2008

Janus--a comprehensive tool investigating the two faces of transcription

scientific article

LINGO1 is not associated with Parkinson's disease in German patients

scientific article published in September 2010

LINGO1 polymorphisms are associated with essential tremor in Europeans

scientific article published in April 2010

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

scientific article

Lactobacilli, bifidobacteria and E. coli nissle induce pro- and anti-inflammatory cytokines in peripheral blood mononuclear cells

scientific article

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

scientific article

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

Leveraging ethnic group incidence variation to investigate genetic susceptibility to glioma: a novel candidate SNP approach

scientific article

Life-threatening chronic enteritis due to colonization of the small bowel with Stenotrophomonas maltophilia

scientific article published on August 2005

Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study

scientific article published in 2008

Limited evidence for parent-of-origin effects in inflammatory bowel disease associated loci

scientific article

Linkage analysis identifies novel genetic modifiers of microbiome traits in families with inflammatory bowel disease

scientific article published in 2022

Linkage disequilibrium patterns and tagSNP transferability among European populations

scientific article

Low level of the mtDNA(4977) deletion in blood of exceptionally old individuals

scientific article

Male-specific association between MT-ND4 11719 A/G polymorphism and ulcerative colitis: a mitochondria-wide genetic association study

scientific article

Massively parallel RNA sequencing identifies a complex immune gene repertoire in the lophotrochozoan Mytilus edulis

scientific article published on 20 March 2012

Mechanisms of infliximab: the reverse side of a drug effect

scientific article published on February 2004

Mesalamine with MMX technology for the treatment of ulcerative colitis

scientific article published on June 2008

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scientific journal article

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

scientific article

Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

scientific article

Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?

scientific article published on 23 October 2009

Metabolic signature of electrosurgical liver dissection

scientific article published on 13 September 2013

Method for preparing single-stranded DNA templates for Pyrosequencing using vector ligation and universal biotinylated primers.

scientific article

Microbial pattern recognition causes distinct functional micro-RNA signatures in primary human monocytes

scientific article (publication date: 2012)

Microbiomarkers in inflammatory bowel diseases: caveats come with caviar

scientific article published on 21 July 2017

Missense variants in NOX1 and p22phox in a case of very-early-onset inflammatory bowel disease are functionally linked to NOD2

scientific article published on 01 February 2019

Mitochondrial DNA variants in obesity

scientific article

Modulation of nuclear factor E2-related factor-2 (Nrf2) activation by the stress response gene immediate early response-3 (IER3) in colonic epithelial cells: a novel mechanism of cellular adaption to inflammatory stress

scientific article published on 5 December 2013

Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis

scientific article

N-linked glycosylation is essential for the stability but not the signaling function of the interleukin-6 signal transducer glycoprotein 130.

scientific article

NOD-like receptors and human diseases.

scientific article published on 27 January 2007

NOD2, IL23R and ATG16L1 polymorphisms in Lithuanian patients with inflammatory bowel disease

scientific article

NOD2-C2 - a novel NOD2 isoform activating NF-kappaB in a muramyl dipeptide-independent manner

scientific article

NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer.

scientific article published on 2 January 2013

Natalizumab Induction and Maintenance Therapy for Crohn's Disease

scientific article

National differences in ulcerative colitis experience and management among patients from five European countries and Canada: an online survey

scientific article published on 23 August 2012

Neolithic and medieval virus genomes reveal complex evolution of hepatitis B.

scientific article published on 10 May 2018

New gene functions in megakaryopoiesis and platelet formation

scientific article published on 30 November 2011

New loci associated with kidney function and chronic kidney disease

scientific article

New susceptibility locus for coronary artery disease on chromosome 3q22.3.

scientific article published on 08 February 2009

New tools and approaches for improved management of inflammatory bowel diseases.

scientific article published on 16 April 2014

No association between microsomal triglyceride transfer protein (MTP) haplotype and longevity in humans

scientific article

No or only population-specific effect of PON1 on human longevity: a comprehensive meta-analysis

scientific article published on April 2010

Nod2 is essential for temporal development of intestinal microbial communities.

scientific article

Nonelectrophoretic method for high-throughput HLA-DRB1 group genotyping.

scientific article

On the use of general control samples for genome-wide association studies: genetic matching highlights causal variants

scientific article published on 24 January 2008

Optimising the Inflammatory Bowel Disease Unit to Improve Quality of Care: Expert Recommendations

scientific article

Oral glutamine supplementation improves intestinal permeability dysfunction in a murine acute graft-vs.-host disease model

scientific article published on 31 January 2013

Osteopontin as two-sided mediator of intestinal inflammation

scientific article

Overview: interleukin-16 and its role in inflammatory bowel disease.

scientific article

Paneth cells as a site of origin for intestinal inflammation.

scientific article

Perception gaps between patients with ulcerative colitis and healthcare professionals: an online survey ⬇️

scientific article published on August 15, 2012

Pharmacogenetics of inflammatory bowel disease

scientific article published on June 2004

Pharmacogenomics in gastrointestinal disorders.

scientific article

Phase II evaluation of anti-MAdCAM antibody PF-00547659 in the treatment of Crohn's disease: report of the OPERA study

scientific article published on 5 October 2017

Phenotypes of organ involvement in sarcoidosis

scientific article published on 25 January 2018

Phylogenetically widespread alternative splicing at unusual GYNGYN donors

scientific article published on January 2006

Physicochemical analysis and biological characterization of FKB327 as a biosimilar to adalimumab

scientific article published on 01 June 2020

Pipeline for large-scale microdroplet bisulfite PCR-based sequencing allows the tracking of hepitype evolution in tumors

scientific article

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

scientific article (publication date: 11 August 2012)

Polymorphisms in MC3R promoter and CTSZ 3'UTR are associated with tuberculosis susceptibility

scientific article

Polymorphisms in the 3'-untranslated region of the CDH1 gene are a risk factor for primary gastric diffuse large B-cell lymphoma

scientific article

Polymorphisms in the glial glutamate transporter SLC1A2 are associated with essential tremor

scientific journal article

Polymorphisms in the interleukin-1 (IL1) gene cluster are not associated with aggressive periodontitis in a large Caucasian population

article

Polymorphisms in the mitochondrial oxidative phosphorylation chain genes as prognostic markers for colorectal cancer

scientific article

Polymorphisms in the mitochondrially encoded ATP synthase 8 gene are associated with susceptibility to bullous pemphigoid in the German population.

scientific article

Polymorphisms in the superoxidase dismutase genes reveal no association with human longevity in Germans: a case-control association study

scientific article published on 22 October 2013

Polymorphisms of the IL12B and IL23R genes are associated with psoriasis

scientific article

Pooled Resequencing of 122 Ulcerative Colitis Genes in a Large Dutch Cohort Suggests Population-Specific Associations of Rare Variants in MUC2

scientific article

PopGen: population-based recruitment of patients and controls for the analysis of complex genotype-phenotype relationships

scientific article

Postprandial plasma adiponectin decreases after glucose and high fat meal and is independently associated with postprandial triacylglycerols but not with -- 11388 promoter polymorphism

scientific article published on 30 July 2007

Predictive value of serologic markers in a population-based Norwegian cohort with inflammatory bowel disease

scientific article published in March 2009

Predictors of gallstone composition in 1025 symptomatic gallstones from Northern Germany

scientific article

Pregnancy in primary sclerosing cholangitis

scientific article published on 21 February 2011

Prevalence of CARD15/NOD2 mutations in Caucasian healthy people

scientific article

Prognostic relevance of gastric cancer staging by endoscopic ultrasound

scientific article published on 6 October 2012

Proposal for an anti-TNF-exit strategy based on trough serum level

scientific article published on 8 April 2017

Prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism and parameters of the metabolic syndrome

scientific article

Protective mucosal immunity mediated by epithelial CD1d and IL-10.

scientific article

Psoriasis and cardiometabolic traits: modest association but distinct genetic architectures

scientific article

Publisher Correction: Identification and characterization of two functional variants in the human longevity gene FOXO3.

scientific article published on 17 January 2018

Putative association between a new polymorphism in exon 3 (Arg109Cys) of the pancreatic colipase gene and type 2 diabetes mellitus in two independent Caucasian study populations

scientific article

Quality of life in patients with active ulcerative colitis treated with selective leukocyte apheresis

scientific article published on March 2007

Quantification of intestinal bacterial populations by real-time PCR with a universal primer set and minor groove binder probes: a global approach to the enteric flora

scientific article

Quantifying the heritability of glioma using genome-wide complex trait analysis

scientific article

RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition

scientific article published on 3 December 2012

Randomised trial and open-label extension study of an anti-interleukin-6 antibody in Crohn's disease (ANDANTE I and II).

scientific article published on 15 December 2017

Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

scientific article

Rare copy number variation discovery and cross-disorder comparisons identify risk genes for ADHD.

scientific article

Recent transfer of an iron-regulated gene from the plastid to the nuclear genome in an oceanic diatom adapted to chronic iron limitation

scientific article

Recommendations for the treatment of Crohn's disease with tumor necrosis factor antagonists: an expert consensus report

scientific article

Recommendations for the treatment of ulcerative colitis with infliximab: a gastroenterology expert group consensus

scientific article

Recurrence of gallstones after cholecystectomy is associated with ABCG5/8 genotype

scientific article

Recurrent microdeletions at 15q11.2 and 16p13.11 predispose to idiopathic generalized epilepsies

scientific article

Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

scientific article

Refinement of the MHC risk map in a scandinavian primary sclerosing cholangitis population

scientific article

Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion

scientific article

Reinduction with Certolizumab Pegol in Patients with Crohn's Disease Experiencing Disease Exacerbation: 7-Year Data from the PRECiSE 4 Study

scientific article

Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease

scientific article published on 24 March 2008

Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis

scientific article published on 27 April 2008

Replication study of ulcerative colitis risk loci in a Lithuanian-Latvian case-control sample.

scientific article published in October 2013

Risk factors in German twins with inflammatory bowel disease: Results of a questionnaire-based survey ⬇️

scientific article published on February 1, 2012

Role of CCL20 mediated immune cell recruitment in NF-κB mediated TRAIL resistance of pancreatic cancer

scientific article published on 7 February 2017

Role of NOD2/CARD15 in coronary heart disease

scientific article

SGCaller: a program to call and review genotypes measured by sequencing

scientific article

SNP discovery performance of two second-generation sequencing platforms in the NOD2 gene region

scientific article

SNP-based analysis of genetic substructure in the German population.

scientific article

SNPSplicer: systematic analysis of SNP-dependent splicing in genotyped cDNAs

scientific article published on November 2006

Safety of Long-term Treatment With Certolizumab Pegol in Patients With Crohn's Disease, Based on a Pooled Analysis of Data From Clinical Trials

scientific article

Sarcoidosis is associated with a truncating splice site mutation in BTNL2.

scientific article

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

scientific article published on 5 October 2008

Sequencing and genotypic analysis of the triosephosphate isomerase (TPI1) locus in a large sample of long-lived Germans

scientific article published on 29 May 2008

Signal transducer of inflammation gp130 modulates atherosclerosis in mice and man

scientific article

Single-cell expression profiling of dopaminergic neurons combined with association analysis identifies pyridoxal kinase as Parkinson's disease gene

scientific article

Single-nucleotide polymorphisms in NAGNAG acceptors are highly predictive for variations of alternative splicing

scientific article

Sirtuin 1 (SIRT1) sequence variation is not associated with exceptional human longevity

scientific article published on 27 October 2005

Smoking cessation induces profound changes in the composition of the intestinal microbiota in humans

scientific article published in 2013

Soluble receptor for advanced glycation end products as a potential biomarker to predict weight loss and improvement of insulin sensitivity by a very low calorie diet of obese human subjects

scientific article published on 21 March 2015

Soluble tumor necrosis factor (TNF) receptor-1 induces apoptosis via reverse TNF signaling and autocrine transforming growth factor-beta1.

scientific article

Sparse Modeling Reveals miRNA Signatures for Diagnostics of Inflammatory Bowel Disease

scientific article published on 14 October 2015

Stratification by CARD15 variant genotype in a genome-wide search for inflammatory bowel disease susceptibility loci

scientific article published on 13 September 2003

Structural localization of disease-associated sequence variations in the NACHT and LRR domains of PYPAF1 and NOD2.

scientific article published on November 2003

Structural variation of chromosomes in autism spectrum disorder

scientific article

Swedish population substructure revealed by genome-wide single nucleotide polymorphism data

scientific article published in 2011

Systematic association mapping identifies NELL1 as a novel IBD disease gene

scientific article published in 2007

Systematic evaluation of the effect of common SNPs on pre-mRNA splicing

scientific article published in April 2009

TBX21 gene variants increase childhood asthma risk in combination with HLX1 variants

scientific article

TFG, a target of chromosome translocations in lymphoma and soft tissue tumors, fuses to GPR128 in healthy individuals

scientific article

TNF-alpha and IFN-gamma regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells

scientific article published in April 2003

TRAIL/NF-κB/CX3CL1 Mediated Onco-Immuno Crosstalk Leading to TRAIL Resistance of Pancreatic Cancer Cell Lines.

scientific article published on 4 June 2018

Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans

scientific article

Technology-specific error signatures in the 1000 Genomes Project data

scientific article

Terminal part of thoracic duct: high-resolution US imaging

scientific article published on 31 July 2009

The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population

scientific article

The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organization: when to start, when to stop, which drug to choose, and how to predict response?

scientific article

The Met-196 -> Arg variation of human tumor necrosis factor receptor 2 (TNFR2) affects TNF-alpha-induced apoptosis by impaired NF-kappaB signaling and target gene expression

scientific article published on 30 November 2004

The NLR gene family: a standard nomenclature

scientific article

The antibiotic resistome and microbiota landscape of refugees from Syria, Iraq and Afghanistan in Germany.

scientific article published on 20 February 2018

The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption

scientific article

The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific

scientific article

The complex interplay of NOD-like receptors and the autophagy machinery in the pathophysiology of Crohn disease

scientific article published on 10 December 2010

The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease

scientific article

The effect of FABP2 promoter haplotype on response to a diet with medium-chain triacylglycerols ⬇️

scientific article published on January 24, 2012

The expression of the beta-defensins hBD-2 and hBD-3 is differentially regulated by NF-kappaB and MAPK/AP-1 pathways in an in vitro model of Candida esophagitis

scientific article published on 12 June 2009

The functional -374T/A polymorphism of the receptor for advanced glycation end products may modulate Crohn's disease

scientific article

The large non-coding RNA ANRIL, which is associated with atherosclerosis, periodontitis and several forms of cancer, regulates ADIPOR1, VAMP3 and C11ORF10.

scientific article published on 27 June 2013

The level of secretory leukocyte protease inhibitor is decreased in metastatic head and neck squamous cell carcinoma

scientific article

The minor allele of the PPARgamma2 pro12Ala polymorphism is associated with lower postprandial TAG and insulin levels in non-obese healthy men.

scientific article published in May 2007

The neuronal transporter gene SLC6A15 confers risk to major depression

scientific article

The nucleotide-binding oligomerization domain-like receptor NLRC5 is involved in IFN-dependent antiviral immune responses

scientific article

The role of pharmacogenomics in the prediction of efficacy of anti-TNF therapy in patients with Crohn's disease

scientific article published on July 2004

Three ulcerative colitis susceptibility loci are associated with primary sclerosing cholangitis and indicate a role for IL2, REL, and CARD9

scientific article

Tofacitinib as Induction and Maintenance Therapy for Ulcerative Colitis

scientific article published on May 2017

Tofacitinib for induction and maintenance therapy of Crohn's disease: results of two phase IIb randomised placebo-controlled trials

scientific article published on 16 February 2017

Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology

scientific article

Toward the blood-borne miRNome of human diseases.

scientific article

Towards a molecular risk map--recent advances on the etiology of inflammatory bowel disease

scientific article

Transcriptional activity of the dominant gut mucosal microbiota in chronic inflammatory bowel disease patients

scientific article

Transcriptome and genome sequencing uncovers functional variation in humans

scientific article

Treatment of Crohn's disease with certolizumab pegol

scientific article published in September 2007

Twin study indicates loss of interaction between microbiota and mucosa of patients with ulcerative colitis

scientific article

Ulcerative colitis: conservative management and long-term effects

scientific article published on 5 May 2004

Ultrashort and progressive 4sU-tagging reveals key characteristics of RNA processing at nucleotide resolution

scientific article

Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease.

scientific article

Uncovering the evolutionary history of innate immunity: the simple metazoan Hydra uses epithelial cells for host defence

scientific article published on 12 November 2008

Unifying candidate gene and GWAS Approaches in Asthma

scientific article

Use of domesticated pigs by Mesolithic hunter-gatherers in northwestern Europe

scientific article (publication date: 2013)

Ustekinumab induction and maintenance therapy in refractory Crohn's disease

scientific article

Validation of a two-step quality control approach for a large-scale human urine metabolomic study conducted in seven experimental batches with LC/QTOF-MS.

scientific article published on January 2015

Validation of reported genetic risk factors for periodontitis in a large-scale replication study.

scientific article published on 16 April 2013

Validation of treatment strategies for enterohaemorrhagic Escherichia coli O104:H4 induced haemolytic uraemic syndrome: case-control study

scientific article

Vedolizumab in the treatment of chronic, antibiotic-dependent or refractory pouchitis

scientific article published on 19 December 2017

Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns

scientific article

Whole genome and exome sequencing of monozygotic twins discordant for Crohn's disease.

scientific article

Widespread occurrence of alternative splicing at NAGNAG acceptors contributes to proteome plasticity

scientific article

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

scientific article

XIAP variants in male Crohn's disease.

scientific article

mTNF reverse signalling induced by TNFα antagonists involves a GDF-1 dependent pathway: implications for Crohn's disease.

scientific article

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