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List of works by Stefan Dübel

A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations

scientific article published on 07 July 2021

A TNF receptor antagonistic scFv, which is not secreted in mammalian cells, is expressed as a soluble mono- and bivalent scFv derivative in insect cells

scientific article published on October 1997

A community standard format for the representation of protein affinity reagents

scientific article

A comparative study of different vector designs for the mammalian expression of recombinant IgG antibodies

scientific article published on 13 November 2006

A family of vectors for surface display and production of antibodies.

scientific article

A helper phage to improve single-chain antibody presentation in phage display

scientific article

A human scFv antibody generation pipeline for proteome research

scientific article

A multi-Fc-species system for recombinant antibody production

scientific article

A single chain antibody obtained by cell panning of antibody phage inhibits homoaggregation of human leukemia cells.

scientific article published in January 2004

A single-chain TNF receptor antagonist is an effective inhibitor of TNF mediated cytotoxicity.

scientific article published on February 1995

A strategy to identify linker-based modules for the allosteric regulation of antibody-antigen binding affinities of different scFvs

scientific article published on 5 January 2017

A surface expression vector for antibody screening

scientific article

A vector for the removal of deletion mutants from antibody libraries

scientific article published in May 1992

Affinity Measurements of Antibody Fragments on Phage by Quartz Crystal Microbalance (QCM)

Affinity enhancement of a recombinant antibody: formation of complexes with multiple valency by a single-chain Fv fragment-core streptavidin fusion

scientific article published in February 1996

Affinity maturation by phage display

scientific article

Affinity-matured variants derived from nimotuzumab keep the original fine specificity and exhibit superior biological activity

scientific article published on 27 January 2020

Amino acid sequence based PCR primers for amplification of rearranged human heavy and light chain immunoglobulin variable region genes

scientific article published on 01 February 1995

Analysis of IgG heavy chain to light chain ratio with mutant Encephalomyocarditis virus internal ribosome entry site

scientific article published on 20 October 2007

Analysis of Single Chain Antibody Sequences Using the VBASE2 Fab Analysis Tool

article

Analysis of protein interactions with immobilized Peptide arrays synthesized on membrane supports

scientific article published on 01 September 2006

Animal-free alternatives and the antibody iceberg

scientific article published on 12 October 2020

Antibodies inside of a cell can change its outside: Can intrabodies provide a new therapeutic paradigm?

scientific article

Antibody Phage Display

Antibody Production: Human, Recombinant

article

Antibody fusion proteins with human ribonucleases 1 to 8.

scientific article published on 10 April 2018

Antibody production in Bacillus megaterium: strategies and physiological implications of scaling from microtiter plates to industrial bioreactors

scientific article published on 7 November 2011

Antibody-targeted RNase fusion proteins (immunoRNases) for cancer therapy

scientific article published on June 2008

Bacterial expression and refolding of single-chain Fv fragments with C-terminal cysteines.

scientific article

Bacterial surface presentation of proteins and peptides: an alternative to phage technology?

scientific article published on 01 January 1993

Baculovirus expression cassette vectors for rapid production of complete human IgG from phage display selected antibody fragments

scientific article

Beyond natural antibodies: the power of in vitro display technologies

scientific article

Bifunctional and multimeric complexes of streptavidin fused to single chain antibodies (scFv)

scientific article published on 01 January 1995

Cell differentiation in the head of Hydra

Cell surface display of a single-chain antibody for attaching polypeptides.

scientific article

Cell-Type Targeted NF-kappaB Inhibition for the Treatment of Inflammatory Diseases

scientific article published on 06 July 2020

Cell-free eukaryotic systems for the production, engineering, and modification of scFv antibody fragments

scientific article published on 15 July 2014

Cell-free synthesis of functional antibodies using a coupled in vitro transcription-translation system based on CHO cell lysates

scientific article published on 20 September 2017

Characterization of the epitope recognized by a monoclonal antibody directed against the largest subunit of Drosophila RNA polymerase II.

scientific article published in August 1995

Cloning and Expression of Single-Chain Fragments (scFv) from Mouse and Rat Hybridomas

scientific article

Cloning and cytotoxicity of a human pancreatic RNase immunofusion

scientific article published on June 1997

Cloning of Variable Domains from Mouse Hybridoma by PCR

Cloning single-chain antibody fragments (scFv) from hybridoma cells

scientific article

Construction of human naive antibody gene libraries

scientific article

Construction of scFv from Hybridoma by Two-Step Cloning

Culture and Transfection of Zebrafish Primary Cells

scientific article published on 17 August 2018

Cytosolic Delivery of Macromolecules in Live Human Cells Using the Combined Endosomal Escape Activities of a Small Molecule and Cell Penetrating Peptides

scientific article published on 31 October 2019

Delivery of antibodies to the cytosol: debunking the myths

scientific article

Design, construction, and in vitro analysis of A33scFv::CDy, a recombinant fusion protein for antibody-directed enzyme prodrug therapy in colon cancer.

scientific article published in October 2007

Designing Human Antibodies by Phage Display

scientific article published on 25 August 2017

Determination of phage antibody affinities to antigen by a microbalance sensor system

scientific article

Development of Neutralizing and Non-neutralizing Antibodies Targeting Known and Novel Epitopes of TcdB of Clostridioides difficile

scientific article published on 06 December 2018

Development of human antibody fragments using antibody phage display for the detection and diagnosis of Venezuelan equine encephalitis virus (VEEV)

scientific article

Die Antikörperfabrik: Antikörper für jedes Protein

Differentiation pathways of ectodermal epithelial cells in hydra

scientific article published on 01 January 1987

Directed evolution of super-secreted variants from phage-displayed human Interleukin-2

scientific article published in Scientific Reports

Effects of unpaired cysteines on yield, solubility and activity of different recombinant antibody constructs expressed in E. coli

article

Efficient production of soluble recombinant single chain Fv fragments by a Pseudomonas putida strain KT2440 cell factory

scientific article (publication date: 21 February 2011)

Embryonic zebrafish primary cell culture for transfection and live cellular and subcellular imaging

scientific article published on 9 August 2017

Enrichment of open reading frames presented on bacteriophage M13 using hyperphage.

scientific article published in September 2006

Epitope structures recognised by antibodies against the major coat protein (g8p) of filamentous bacteriophage fd (Inoviridae)

scholarly article by S Kneissel et al published 23 April 1999 in Journal of Molecular Biology

Epitopes fused to F-pilin are incorporated into functional recombinant pili.

scientific article

Evaluating the Delivery of Proteins to the Cytosol of Mammalian Cells.

scientific article published on January 2017

Evaluation of human pancreatic RNase as effector molecule in a therapeutic antibody platform

scientific article published on 15 January 2014

Expression of a bispecific dsFv–dsFv′ antibody fragment in Escherichia coli

scientific article published on 01 October 2000

Fine mapping of the antigen-antibody interaction of scFv215, a recombinant antibody inhibiting RNA polymerase II from Drosophila melanogaster

scientific article published in March 1999

Functional Minipreps of scFv-Antibody Fragments

Functional characterization of recombinant chloroplast signal recognition particle.

scientific article

Functional knock down of VCAM1 in mice mediated by endoplasmatic reticulum retained intrabodies

scientific article

Functional knockdown of VCAM-1 at the posttranslational level with ER retained antibodies

scientific article

Funktionales Proteom-Display zur Identifikation von Biomarkern

Generating recombinant antibodies to the complete human proteome

scientific article

Generation and analysis of the improved human HAL9/10 antibody phage display libraries

scientific article published on 19 February 2015

Generation of Antibody Gene Libraries from Seropositive Human Donors

article

Generation of Recombinant Antibodies against the beta-(1,6)-Branched beta-(1,3)-D-Glucan Schizophyllan from Immunized Mice via Phage Display.

scientific article

Head activator acts as an autocrine growth factor for NH15-CA2 cells in the G2/mitosis transition

scientific article published on November 1989

Heterogeneous Detection of PCR-Amplified Intimin Gene From

article

High-affinity, human antibody-like antibody fragment (single-chain variable fragment) neutralizing the lethal factor (LF) of Bacillus anthracis by inhibiting protective antigen-LF complex formation

scientific article

Human Anti-Lipopolysaccharid (LPS) antibodies against Legionella with high species specificity

scientific article

Human Antibody Gene Libraries

article

Human antibodies neutralizing diphtheria toxin in vitro and in vivo

scientific article published on 17 January 2020

Human antibodies targeting CD30(+) lymphomas

scientific article

Human antibody RNase fusion protein targeting CD30+ lymphomas.

scientific article published on 29 January 2008

Human antibody libraries in Escherichia coli

scientific article published on July 1995

Human-like antibodies neutralizing Western equine encephalitis virus

scientific article

Hyperphage. Improving antibody presentation in phage display

scientific article

Identification of a new epitope for HIV-neutralizing antibodies in the gp41 membrane proximal external region by an Env-tailored phage display library

scientific article

Identification of a putative Crf splice variant and generation of recombinant antibodies for the specific detection of Aspergillus fumigatus

scientific article (publication date: 13 August 2009)

Identification of epitope regions recognized by tumor inhibitory and stimulatory anti-ErbB-2 monoclonal antibodies: implications for vaccine design

scientific article

Identification of immunogenic antigens from Aspergillus fumigatus by direct multiparameter characterization of specific conventional and regulatory CD4+ T cells

scientific article published on 29 August 2014

Identification of immunogenic proteins and generation of antibodies against Salmonella Typhimurium using phage display

scientific article

Improved microtitre plate production of single chain Fv fragments in Escherichia coli

scientific article

Improving Phage Display Throughput by Using Hyperphage, Miniaturized Titration and pVIII (g8p) ELISA

Influence of the hydromechanical stress and temperature on growth and antibody fragment production with Bacillus megaterium

article

Inhibition of HER3 activation and tumor growth with a human antibody binding to a conserved epitope formed by domain III and IV.

scientific article published on 19 April 2017

Isolation and characterisation of a human-like antibody fragment (scFv) that inactivates VEEV in vitro and in vivo

scientific article

Isolation of IgG antibody Fv-DNA from various mouse and rat hybridoma cell lines using the polymerase chain reaction with a simple set of primers

scientific article published on 01 September 1994

Isolation of a human-like antibody fragment (scFv) that neutralizes ricin biological activity

scientific article

Isolation of scFv fragments specific to OmpD of Salmonella Typhimurium

scientific article

Itolizumab (Alzumab), Mogamulizumab (Poteligeo), and Tositumomab (Bexxar)

Low-cost, in-liquid measuring system using a novel compact oscillation circuit and quartz-crystal microbalances (QCMs) as a versatile biosensor platform

Mating antibody phage display with proteomics

scientific article published in January 2004

Measuring biomolecular binding events with a compact disc player device

scientific article published in December 2005

Microfluidic quartz-crystal-microbalance (QCM) sensors with specialized immunoassays for extended measurement range and improved reusability

Microtubule-dependent cell cycle regulation is implicated in the G2 phase of Hydra cells.

scientific article

Minimum information about a protein affinity reagent (MIAPAR)

scientific article published on 01 July 2010

Mining gut microbiome oligopeptides by functional metaproteome display

scientific article

Modeling Neurodegenerative Spinocerebellar Ataxia Type 13 in Zebrafish Using a Purkinje Neuron Specific Tunable Coexpression System

scientific article published on 12 March 2019

Molecular cloning of the alpha-1 subunit of an omega-conotoxin-sensitive calcium channel ⬇️

scientific article published on June 1, 1992

Molecular cloning of tissue-specific transcripts of a transketolase-related gene: implications for the evolution of new vertebrate genes

scientific article

Multimerization domains for antibody phage display and antibody production

scientific article

Mutations in the N-terminus of the major coat protein (pVIII, gp8) of filamentous bacteriophage affect infectivity

scientific article

NF-κB inhibitor targeted to activated endothelium demonstrates a critical role of endothelial NF-κB in immune-mediated diseases

scientific article published on 23 September 2013

Neue Impulse für den Protein-Knock-down mit intrabodies

New anti-CD30 human pancreatic ribonuclease-based immunotoxin reveals strong and specific cytotoxicity in vivo

scientific article

Novel human recombinant antibodies against Mycobacterium tuberculosis antigen 85B

scientific article

ORFeome Phage Display

scientific article published in January 2018

Oligomeric forms of single chain immunoglobulin (scIgG).

scientific article

On the influence of vector design on antibody phage display

scientific article

Parallelized Microscale Expression of Soluble scFv

scientific article published on 01 January 2019

Parameters affecting the display of antibodies on phage

scientific article published on June 2005

Perspectives for systematic in vitro antibody generation

scientific article published on 26 August 2005

Phage display derived therapeutic antibodies

scientific article

Phage display vectors for the in vitro generation of human antibody fragments.

scientific article

Phage display-based identification and potential diagnostic application of novel antigens from Mycoplasma mycoides subsp. mycoides small colony type.

scientific article published on 20 October 2009

Primary structure and functional expression of heavy- and light-chain variable region genes of a monoclonal antibody specific for human fibrin

scientific article published on June 1997

Primary structure and functional scFv antibody expression of an antibody against the human protooncogen c-myc

scientific article published on June 1997

Primary structure of the antigen-binding domains of a human oligodendrocyte-reactive IgM monoclonal antibody derived from a patient with multiple sclerosis

scientific article published in September 1999

Production of Recombinant Human IgG Antibodies in the Baculovirus Expression System

Production of Recombinant Human IgG Antibodies in the Baculovirus Expression System

article

Production of monoclonal antibodies against epitopes of the main coat protein of filamentous fd phages

scientific article published in May 1994

Production of recombinant antibody fragments in Bacillus megaterium

scientific article published on 15 January 2007

Production of single chain Fab (scFab) fragments in Bacillus megaterium

scientific article published on 27 November 2007

Production of single chain fragment variable (scFv) antibodies in Escherichia coli using the LEX™ bioreactor

scientific article published on 9 August 2012

Production systems for recombinant antibodies

scientific article published on May 2008

Protein stabilization through phage display

scientific article

ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome

article

Radiometal-labeled anti-VCAM-1 nanobodies as molecular tracers for atherosclerosis - impact of radiochemistry on pharmacokinetics

scientific article published on 01 February 2019

Rapid titration of multiple samples of filamentous bacteriophage (M13) on nitrocellulose filters

scientific article

Recent Advances with ER Targeted Intrabodies

scientific article

Recent developments in antibody engineering

scientific article

Recombinant Antibodies

Recombinant antibodies and in vitro selection technologies

scientific article

Recombinant antibody fragments allow repeated measurements of C-reactive protein with a quartz crystal microbalance immunosensor

scientific article

Recombinant human monoclonal antibodies. Basic principles of the immune system transferred to E. coli

scientific article

Recombinant single-chain Fv fragments carrying C-terminal cysteine residues: Production of bivalent and biotinylated miniantibodies

article

Recombinant therapeutic antibodies

scientific article published on 16 January 2007

Recombinant variants of antibody 138H11 against human gamma-glutamyltransferase for targeting renal cell carcinoma

scientific article published on January 2006

Regulated secretion and purification of recombinant antibodies inE. coli

Rekombinante Antikörper: Werkzeuge gegen Krebs, Infektionen und Autoimmunerkrankungen?

Reproducibility: bypass animals for antibody production

scientific article published on 15 May 2020

Ribonucleases and immunoRNases as anticancer drugs

scientific article published on January 2009

Rise and fall of an anti-MUC1 specific antibody

scientific article (publication date: 14 January 2011)

SRP and Sec pathway leader peptides for antibody phage display and antibody fragment production in E. coli

scientific article

Screening of molecular repertoires by microbial surface display

scientific article

Selection of recombinant antibodies from antibody gene libraries

scientific article

Selection of recombinant antibodies from antibody gene libraries

article

Separation of E. coli expressing functional cell-wall bound antibody fragments by FACS.

scientific article published on June 1996

Sequence defined antibodies improve the detection of cadherin 2 (N-cadherin) during zebrafish development

scientific article published on 28 December 2017

Simultaneous mutagenesis of antibody CDR regions by overlap extension and PCR

scientific article published on 01 August 1994

Single Chain Antibodies as Tools to Study transforming growth factor-β-Regulated SMAD Proteins in Proximity Ligation-Based Pharmacological Screens

scientific article

Single amino acid fingerprinting of the human antibody repertoire with high density peptide arrays

scientific article published on 3 February 2017

Single chain Fab (scFab) fragment

scientific article published on 8 March 2007

Single-chain antibody streptavidin fusions: Tetrameric bifunctional scFv-complexes with biotin binding activity and enhanced affinity to antigen

article published in 1995

Single-chain antibody streptavidin fusions: tetrameric bifunctional scFv-complexes with biotin binding activity and enhanced affinity to antigen.

scientific article

Specific in vivo knockdown of protein function by intrabodies

scientific article

Structural differences of amyloid-β fibrils revealed by antibodies from phage display

scientific article published on 18 June 2015

Structural insights into antigen recognition of an anti-β-(1,6)-β-(1,3)-D-glucan antibody

scientific article published in Scientific Reports

Suppression of p75 neurotrophin receptor surface expression with intrabodies influences Bcl-xL mRNA expression and neurite outgrowth in PC12 cells

scientific journal article

Surface display of antibodies

scientific article published in January 1994

Targeted therapeutic RNases (ImmunoRNases)

Targeting antibodies to the cytoplasm

scientific article published on January 2011

Targeting recombinant antibodies to the surface of Escherichia coli: fusion to a peptidoglycan associated lipoprotein

scientific article

Terminal differentiation of ectodermal epithelial stem cells of Hydra can occur in G2 without requiring mitosis or S phase

scientific article published on April 1990

Terminal differentiation of head- and foot-specific epithelial cells occurs at the same location in Hydra tissue without polarity

scientific article published on March 1990

The "sneaking-ligand" approach: cell-type specific inhibition of the classical NF-κB pathway

scientific article published in January 2015

The INNs and outs of antibody nonproprietary names

scientific article published in January 2016

The antibody web

scientific article published on 01 August 2000

The antigen-binding domain of a human IgG-anti-F(ab')2 autoantibody

scientific article

The influence of antibody fragment format on phage display based affinity maturation of IgG.

scientific article

The sneaking ligand approach for cell type-specific modulation of intracellular signalling pathways

scientific article published on 31 August 2017

The translocon protein Sec61 mediates antigen transport from endosomes in the cytosol for cross-presentation to CD8(+) T cells

scientific article published on 12 May 2015

Therapeutic Antibodies - from Past to Future

Therapeutic antibodies and antibody fusion proteins

scientific article published on January 2003

Thiophilic Adsorption Chromatography of Recombinant Single-Chain Antibody Fragments

scientific article published on 01 July 1994

Towards proteome scale antibody selections using phage display

scientific article

Universal antibody libraries on phage and bacteria.

scientific article published on January 1993

Using the power of in vitro selection by phage display to identify recombinant antibodies with optimised properties to various life threatening viruses

article by Stefan Dübel published 2011 in Journal of antivirals & antiretrovirals

Ustekinumab (Stelara®1)2

Utilisation of antibody microarrays for the selection of specific and informative antibodies from recombinant library binders of unknown quality.

scientific article published on 17 December 2015

V-gene amplification revisited - An optimised procedure for amplification of rearranged human antibody genes of different isotypes

scientific article

When monoclonal antibodies are not monospecific: Hybridomas frequently express additional functional variable regions

scientific article published on 27 February 2018

cTAGE: a cutaneous T cell lymphoma associated antigen family with tumor-specific splicing

scientific article

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