Search filters

List of works by W. Mark Saltzman

A "top-down" approach to actuate poly(amine-co-ester) terpolymers for potent and safe mRNA delivery

scientific article published on 25 May 2018

A nanoscopic multivalent antigen-presenting carrier for sensitive detection and drug delivery to T cells

scientific article published in March 2007

A sunblock based on bioadhesive nanoparticles

scientific article

Alginate microparticles loaded with basic fibroblast growth factor induce tissue coverage in a rat model of myelomeningocele

scientific article published on 05 October 2018

An electrospun scaffold integrating nucleic acid delivery for treatment of full-thickness wounds.

scientific article published on 27 February 2013

Anti-tumor Activity of miniPEG-γ-Modified PNAs to Inhibit MicroRNA-210 for Cancer Therapy.

scientific article published on 12 September 2017

Biodegradable PEG-poly(ω-pentadecalactone-co-p-dioxanone) nanoparticles for enhanced and sustained drug delivery to treat brain tumors

scholarly article by Evan M Chen et al published September 2018 in Biomaterials

Biodegradable bioadhesive nanoparticle incorporation of broad-spectrum organic sunscreen agents

scientific article published on 06 July 2018

Biodegradable meshes printed with extracellular matrix proteins support micropatterned hepatocyte cultures

scientific article

Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery ⬇️

scientific article published on December 4, 2011

Biodegradation, biocompatibility, and drug delivery in poly(ω-pentadecalactone-co-p-dioxanone) copolyesters

scientific article

Biomaterials with hierarchically defined micro- and nanoscale structure

scientific article published on August 2004

Blocking MHC class II on human endothelium mitigates acute rejection

scientific article published on 21 January 2016

Canonical and Non-Canonical Barriers Facing AntimiR Cancer Therapeutics ⬇️

scientific article published on January 1, 2013

Cell penetrating peptide-modified poly(lactic-co-glycolic acid) nanoparticles with enhanced cell internalization

scientific article

Cellular distribution of injected PLGA-nanoparticles in the liver

scientific article published on 04 March 2016

Centrifugal seeding increases seeding efficiency and cellular distribution of bone marrow stromal cells in porous biodegradable scaffolds

scientific article published on November 2007

Clostridium perfringens enterotoxin C-terminal domain labeled to fluorescent dyes for in vivo visualization of micrometastatic chemotherapy-resistant ovarian cancer

scientific article published on 9 June 2015

Controlled DNA delivery systems

scientific article published in August 1999

Controlled delivery of VEGF via modulation of alginate microparticle ionic crosslinking

scientific article

Controlled protein delivery in the generation of microvascular networks.

scientific article

Controlled release of proteins to tissue transplants for the treatment of neurodegenerative disorders

scientific article published on December 1996

Controlled surface modification with poly(ethylene)glycol enhances diffusion of PLGA nanoparticles in human cervical mucus

scientific article published on January 2009

Convection-enhanced delivery of camptothecin-loaded polymer nanoparticles for treatment of intracranial tumors

scientific article

Cultures of cells from fetal rat brain: methods to control composition, morphology, and biochemical activity

scientific article

Debugging the genetic code: non-viral in vivo delivery of therapeutic genome editing technologies

scientific article published on 21 August 2018

Degradable bioadhesive nanoparticles for prolonged intravaginal delivery and retention of elvitegravir.

scientific article

Design opportunities for actively targeted nanoparticle vaccines

scientific article published on January 2008

Development of PTH eluting microspheres for the treatment of hypoparathyroidism

scientific article published on 27 August 2007

Development of a model system for preliminary evaluation of tissue-engineered vascular conduits

scientific article published in April 2006

Development of a parathyroid hormone-controlled release system as a potential surgical treatment for hypoparathyroidism

scientific article published in January 2005

Dilation and degradation of the brain extracellular matrix enhances penetration of infused polymer nanoparticles.

scientific article

Direct, quantitative, and noninvasive imaging of the transport of active agents through intact brain with positron emission tomography.

scientific article published on October 2013

Distribution of polymer nanoparticles by convection-enhanced delivery to brain tumors.

scientific article published on 07 April 2016

Drug delivery: Stealth particles give mucus the slip

scientific article

Dual delivery of VEGF and MCP-1 to support endothelial cell transplantation for therapeutic vascularization

scientific article

Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells

scientific article published on 12 December 2016

Effect of extracellular matrix elements on the transport of paclitaxel through an arterial wall tissue mimic

scientific article

Efficient gene disruption in cultured primary human endothelial cells by CRISPR/Cas9.

scientific article

Engineering biodegradable nanoparticles for drug and gene delivery

scientific article

Engineering of multifunctional gels integrating highly efficient growth factor delivery with endothelial cell transplantation

scientific article published on May 2008

Enhanced and prolonged cross-presentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticles

scientific article published on January 2006

Enhanced siRNA delivery into cells by exploiting the synergy between targeting ligands and cell-penetrating peptides ⬇️

scientific article published on June 12, 2011

Enhancement of surface ligand display on PLGA nanoparticles with amphiphilic ligand conjugates

scientific article published on 24 June 2011

Enhancing potency of siRNA targeting fusion genes by optimization outside of target sequence

scientific article

Enzyme‐synthesized poly(amine‐co‐esters) as nonviral vectors for gene delivery ⬇️

scientific article published on December 9, 2010

Ex vivo isolated human vessel perfusion system for the design and assessment of nanomedicines targeted to the endothelium

scientific article published on 28 January 2020

Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells

scientific article published on 04 August 2017

Extracellular vesicles mediated exocytosis of antisense peptide nucleic acids

scientific article published on 08 August 2021

Fas ligand and nitric oxide combination to control smooth muscle growth while sparing endothelium

scientific article published on 07 May 2019

Focus on Fundamentals: Achieving Effective Nanoparticle Targeting

scientific article published on 05 June 2018

From in silico hit to long-acting late-stage preclinical candidate to combat HIV-1 infection.

scientific article published on 26 December 2017

Gene expression and mucosal immune responses after vaginal DNA immunization in mice using a controlled delivery matrix

scientific article published in January 2003

Glycoprotein-130 expression is associated with aggressive bladder cancer and is a potential therapeutic target

scientific article published on 31 October 2018

HG-112LOCAL DELIVERY OF RADIOSENSITIZING NANOPARTICLES FOR THE TREATMENT OF PEDIATRIC BRAINSTEM GLIOMAS.

scientific article published on 30 May 2016

High loading efficiency and tunable release of plasmid DNA encapsulated in submicron particles fabricated from PLGA conjugated with poly-L-lysine

scientific article published on 16 April 2008

High-throughput quantitative microscopy-based half-life measurements of intravenously injected agents

scientific article published on 03 February 2020

Highly penetrative, drug-loaded nanocarriers improve treatment of glioblastoma ⬇️

scientific article published on July 16, 2013

Human aortic smooth muscle cells promote arteriole formation by coengrafted endothelial cells.

scientific article published in January 2009

Imaging the delivery of brain-penetrating PLGA nanoparticles in the brain using magnetic resonance

scientific article

Impact of cell type and density on nerve growth factor distribution and bioactivity in 3-dimensional collagen gel cultures

scientific article published in July 2006

Improved cell adhesion and proliferation on synthetic phosphonic acid-containing hydrogels.

scientific article

Improved i.p. drug delivery with bioadhesive nanoparticles

scientific article published on 23 September 2016

Improved threshold selection for the determination of volume of distribution of nanoparticles administered by convection-enhanced delivery

scientific article

In utero nanoparticle delivery for site-specific genome editing.

scientific article

In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery

scientific article (publication date: 26 October 2016)

In vivo distribution of surface-modified PLGA nanoparticles following intravaginal delivery ⬇️

scientific article published on July 8, 2011

Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy

scientific article (publication date: 18 May 2009)

Initial evaluation of the use of USPIO cell labeling and noninvasive MR monitoring of human tissue-engineered vascular grafts in vivo.

scientific article published on 18 August 2008

Intracranial delivery of recombinant nerve growth factor: release kinetics and protein distribution for three delivery systems

scientific article published in February 1999

Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA

scientific article published on 03 May 2009

Ligand-modified gene carriers increased uptake in target cells but reduced DNA release and transfection efficiency

scientific article

Local DNA Repair Inhibition for Sustained Radiosensitization of High-Grade Gliomas

scientific article published on 31 May 2017

Lysis of cold-storage-induced microvascular obstructions for ex vivo revitalization of marginal human kidneys

scientific article published on 05 July 2020

Mathematical modeling of molecular diffusion through mucus

scientific article published on 16 December 2008

MicroRNA silencing for cancer therapy targeted to the tumour microenvironment.

scientific article

Millimeter-scale positioning of a nerve-growth-factor source and biological activity in the brain

scientific article

Modified poly(lactic-co-glycolic acid) nanoparticles for enhanced cellular uptake and gene editing in the lung.

scientific article

Multi-layered nanoparticles for combination gene and drug delivery to tumors.

scientific article

Multifunctional Poly(amine-co-ester-co-ortho ester) for Efficient and Safe Gene Delivery

scientific article

Nanomaterials for convection-enhanced delivery of agents to treat brain tumors

scientific article published on 22 September 2017

Nanomedicine gets personal

scientific article published in November 2015

Nanomedicine: Downsizing tumour therapeutics

scientific article published on 06 June 2012

Nanoparticle delivery of miR-223 to attenuate macrophage fusion

scientific article published on 26 February 2016

Nanoparticle for delivery of antisense γPNA oligomers targeting CCR5 ⬇️

scientific article published on April 1, 2013

Nanoparticle targeting to the endothelium during normothermic machine perfusion of human kidneys

scientific article published in November 2017

Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma

scientific article

Nanoparticle-mediated intratumoral inhibition of miR-21 for improved survival in glioblastoma

scientific article published on 14 February 2019

Nanoparticles Deliver Triplex-forming PNAs for Site-specific Genomic Recombination in CD34+ Human Hematopoietic Progenitors ⬇️

scientific article published on September 21, 2010

Nanoparticles for urothelium penetration and delivery of the histone deacetylase inhibitor belinostat for treatment of bladder cancer ⬇️

scientific article published on June 11, 2013

Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epithelium

scientific article published on 27 April 2015

Nanosystems for simultaneous imaging and drug delivery to T cells

scientific article published on 8 June 2007

Nanotechnology for delivery of peptide nucleic acids (PNAs)

scientific article

Nanotherapy for Cancer: Targeting and Multifunctionality in the Future of Cancer Therapies.

scientific article published on 13 January 2015

New methods for direct delivery of chemotherapy for treating brain tumors.

scientific article

Novel Delivery Strategies for Glioblastoma ⬇️

scientific article published on January 1, 2012

Octa-functional PLGA nanoparticles for targeted and efficient siRNA delivery to tumors

scientific article

Optimizing biodegradable nanoparticle size for tissue-specific delivery

scientific article published on 22 October 2019

PEGylated PLGA nanoparticles for the improved delivery of doxorubicin

scientific article published on 31 March 2009

PEGylated squalenoyl-gemcitabine nanoparticles for the treatment of glioblastoma

scientific article published on 4 August 2016

Paracrine exchanges of molecular signals between alginate-encapsulated pericytes and freely suspended endothelial cells within a 3D protein gel.

scientific article published on 21 August 2013

Parameter estimation methodology in a model of hydrophobic drug release from a polymer coating.

scientific article

Partial correction of cystic fibrosis defects with PLGA nanoparticles encapsulating curcumin

scientific article published on February 2010

Peptide Nucleic Acids and Gene Editing: Perspectives on Structure and Repair

scientific article published on 08 February 2020

Peptide Nucleic Acids as a Tool for Site-Specific Gene Editing.

scientific article published on 11 March 2018

Pericytes modulate endothelial sprouting

scientific article published on 16 September 2013

Pigment epithelium-derived factor (PEDF) suppresses IL-1β-mediated c-Jun N-terminal kinase (JNK) activation to improve hepatocyte insulin signaling

scientific article published on 23 January 2014

Pigment epithelium-derived factor restoration increases bone mass and improves bone plasticity in a model of osteogenesis imperfecta type VI via Wnt3a blockade

scientific article published on 28 April 2016

Poly(Lactic-co-Glycolic Acid) Nanoparticle Delivery of Peptide Nucleic Acids In Vivo

scientific article published on 01 January 2020

Poly(amine-co-ester) nanoparticles for effective Nogo-B knockdown in the liver

scientific article published on 01 May 2019

Poly(omega-pentadecalactone-co-butylene-co-succinate) nanoparticles as biodegradable carriers for camptothecin delivery

scientific article published on 25 July 2009

Polymer delivery systems for site-specific genome editing ⬇️

scientific article published on May 18, 2011

Polymer nanoparticle-mediated delivery of microRNA inhibition and alternative splicing

scientific article

Polymer nanoparticles containing tumor lysates as antigen delivery vehicles for dendritic cell–based antitumor immunotherapy ⬇️

scientific article published on August 6, 2010

Polymer nanoparticles encapsulating siRNA for treatment of HSV-2 genital infection ⬇️

scientific article published on June 15, 2012

Polymeric nanoparticles for drug delivery to the central nervous system ⬇️

scientific article published on December 20, 2011

Polymeric vehicles for nucleic acid delivery

scientific article published on 22 June 2020

Prevention of K-Ras- and Pten-mediated intravaginal tumors by treatment with camptothecin-loaded PLGA nanoparticles.

scientific article

Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression

scientific article published on 17 October 2019

Quantitating Endosomal Escape of a Library of Polymers for mRNA Delivery

scientific article published on 31 January 2020

Quantitative microscopy-based measurements of circulating nanoparticle concentration using microliter blood volumes

scientific article published on 13 April 2017

Radiolabeling of poly(lactic-co-glycolic acid) (PLGA) nanoparticles with biotinylated F-18 prosthetic groups and imaging of their delivery to the brain with positron emission tomography

scientific article

Replacement of bone marrow by bone in rat femurs: the bone bioreactor

scientific article published in February 2008

Reply to Pandey et al.: Understanding the efficacy of a potential antiretroviral drug candidate in humanized mouse model of HIV infection

article published in the Proceedings of the National Academy of Sciences of the United States of America

Shining light on a new class of hydrogels

scientific article published on 01 June 2009

Single-stranded γPNAs for in vivo site-specific genome editing via Watson-Crick recognition

scientific article

Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice

scientific article

Small-diameter biodegradable scaffolds for functional vascular tissue engineering in the mouse model

scientific article published on 27 December 2007

Structural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV

scientific article published on 26 April 2019

Surface chemistry governs cellular tropism of nanoparticles in the brain

scientific article

Surface modification of biodegradable polyesters with fatty acid conjugates for improved drug targeting

scientific article published on 18 April 2005

Surface modified poly(β amino ester)-containing nanoparticles for plasmid DNA delivery

scientific article published on 5 October 2012

Surface-mediated gene transfer from nanocomposites of controlled texture

scientific article published on 18 July 2004

Surface-modified nanoparticles enhance transurothelial penetration and delivery of survivin siRNA in treating bladder cancer

scientific article

Sustained delivery of proangiogenic microRNA-132 by nanoparticle transfection improves endothelial cell transplantation.

scientific article

Synergistic tumor suppression by combined inhibition of telomerase and CDKN1A

scientific article

Synthesis and biological activity of polyethylene glycol-mouse nerve growth factor conjugate

scientific article published on 01 November 1999

Systemic delivery of blood-brain barrier-targeted polymeric nanoparticles enhances delivery to brain tissue

scientific article published on August 2015

Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo

scientific article published on 18 October 2012

Targeted genome modification via triple helix formation

scientific article published on 01 January 2014

The behavioral and biochemical effects of BDNF containing polymers implanted in the hippocampus of rats

scientific article

The effect of hyperbranched polyglycerol coatings on drug delivery using degradable polymer nanoparticles

scientific article

The effect of inflammatory cell-derived MCP-1 loss on neuronal survival during chronic neuroinflammation.

scientific article published on 29 May 2014

The influence of microchannels on neurite growth and architecture

scientific article

The nanomaterial-dependent modulation of dendritic cells and its potential influence on therapeutic immunosuppression in lupus

scientific article

The uptake and intracellular fate of PLGA nanoparticles in epithelial cells

scientific article published on 20 February 2009

Therapeutic Peptide Nucleic Acids: Principles, Limitations, and Opportunities

scientific article published on 19 December 2017

Therapeutic siRNA: principles, challenges, and strategies ⬇️

scientific article published on June 25, 2012

Three Dimensional Bioprinting of a Vascularized and Perfusable Skin Graft Using Human Keratinocytes, Fibroblasts, Pericytes, and Endothelial Cells

scientific article published on 03 December 2019

Tissue-Engineered Microvasculature to Reperfuse Isolated Renal Glomeruli.

scientific article

Tissue-engineered vascular grafts form neovessels that arise from regeneration of the adjacent blood vessel

scientific article

Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling

scientific article

Topographical control of human neutrophil motility on micropatterned materials with various surface chemistry

scientific article

Transplantation of brain cells assembled around a programmable synthetic microenvironment

scientific article

Tunability of Biodegradable Poly(amine- co-ester) Polymers for Customized Nucleic Acid Delivery and Other Biomedical Applications

scientific article published on 28 August 2018

Vaccine delivery by polymeric vehicles in the mouse reproductive tract induces sustained local and systemic immunity

scientific article

ZNF117 regulates glioblastoma stem cell differentiation towards oligodendroglial lineage

scientific article published on 22 April 2022

miR-34a Silences c-SRC to Attenuate Tumor Growth in Triple-Negative Breast Cancer.

scientific article published on 16 December 2015

Paulina is supported by:

About Paulina

Help