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List of works by Wolff Schmiegel

35th Annual Meeting of the European Association for the Study of Diabetes

article

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999

article

A prospective, non-randomized phase II trial of Trastuzumab and Capecitabine in patients with HER2 expressing metastasized pancreatic cancer

scientific article

A randomised phase II study of irinotecan in combination with 5-FU/FA compared with irinotecan alone as second-line treatment of patients with metastatic colorectal carcinoma

scientific article

A soluble form of the giant cadherin Fat1 is released from pancreatic cancer cells by ADAM10 mediated ectodomain shedding

scientific article published in 2014

Age-dependent performance of BRAF mutation testing in Lynch syndrome diagnostics

scientific article published on 01 September 2020

Analysis of U2 small nuclear RNA fragments in the bile differentiates cholangiocarcinoma from primary sclerosing cholangitis and other benign biliary disorders

scientific article published on 31 January 2014

Application of fluorescence difference gel electrophoresis saturation labelling for the analysis of microdissected precursor lesions of pancreatic ductal adenocarcinoma

scientific article published in July 2005

Bevacizumab plus oxaliplatin-based regimens for the treatment of colorectal cancer

scientific article published on 10 June 2009

Blood-based detection of RAS mutations to guide anti-EGFR therapy in colorectal cancer patients: concordance of results from circulating tumor DNA and tissue-based RAS testing

scientific article published on 16 November 2016

Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

scientific article published on 24 July 2019

Cancer risks in Lynch syndrome, Lynch-like syndrome, and familial colorectal cancer type X: a prospective cohort study

scientific article published on 24 May 2020

Capsule endoscopy for small bowel surveillance in hereditary intestinal polyposis and non-polyposis syndromes

scientific article published on January 2004

Cetuximab-based or bevacizumab-based first-line treatment in patients with KRAS p.G13D-mutated metastatic colorectal cancer ⬇️

scientific article published on July 1, 2012

Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells ⬇️

scientific article published on July 6, 2011

Circulating U2 small nuclear RNA fragments as a diagnostic and prognostic biomarker in lung cancer patients.

scientific article

Circulating U2 small nuclear RNA fragments as a novel diagnostic biomarker for pancreatic and colorectal adenocarcinoma

scientific article published on 14 September 2012

Circulating U2 small nuclear RNA fragments as a novel diagnostic biomarker for primary central nervous system lymphoma

scientific article published on 6 August 2015

Colonic cancer and polyps

scientific article

Colorectal carcinoma: the management of polyps, (neo)adjuvant therapy, and the treatment of metastases

scientific article

Complicated fecal microbiota transplantation in a tetraplegic patient with severe Clostridium difficile infection

scientific article published on March 2015

Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

scientific article published on 20 July 2020

Detection of novel biomarkers of liver cirrhosis by proteomic analysis

scientific article

Differential proteome analysis of conditioned media to detect Smad4 regulated secreted biomarkers in colon cancer

scientific article published in July 2005

Divergent mechanisms underlie Smad4-mediated positive regulation of the three genes encoding the basement membrane component laminin-332 (laminin-5).

scientific article

Drug insight: antiangiogenic therapies for gastrointestinal cancers--focus on monoclonal antibodies

scientific article published on April 2008

Effect of KRAS codon13 mutations in patients with advanced colorectal cancer (advanced CRC) under oxaliplatin containing chemotherapy. Results from a translational study of the AIO colorectal study group

scientific article

Efficacy of annual colonoscopic surveillance in individuals with hereditary nonpolyposis colorectal cancer

scientific article published on 14 October 2009

Efficacy of oxaliplatin plus capecitabine or infusional fluorouracil/leucovorin in patients with metastatic colorectal cancer: a pooled analysis of randomized trials

scientific article

Efficacy of recombinant adeno-associated viral vectors serotypes 1, 2, and 5 for the transduction of pancreatic and colon carcinoma cells.

scientific article published on June 2010

Evaluation of the biomarker candidate MFAP4 for non-invasive assessment of hepatic fibrosis in hepatitis C patients

scientific article published on 04 July 2016

Feasibility and diagnostic utility of video capsule endoscopy for the detection of small bowel polyps in patients with hereditary polyposis syndromes.

scientific article

Gastrointestinal bleeding 30 years after a complicated cholecystectomy.

scientific article

Gefitinib in combination with capecitabine as second-line therapy in patients with advanced colorectal cancer (aCRC): a phase I/II study of the Arbeitsgemeinschaft Internistische Onkologie (AIO).

scientific article published on 23 February 2010

Genome-wide analysis associates familial colorectal cancer with increases in copy number variations and a rare structural variation at 12p12.3.

scientific article published on 14 October 2013

Genomic and transcriptomic heterogeneity of colorectal tumors arising in Lynch Syndrome

scientific article published on 20 July 2017

Genotype-phenotype comparison of German MLH1 and MSH2 mutation carriers clinically affected with Lynch syndrome: a report by the German HNPCC Consortium

scientific article published on 14 August 2006

HNPCC: six new pathogenic mutations

scientific article

Hereditary nonpolyposis colorectal cancer (HNPCC)/Lynch syndrome

scientific article

High-level inducible Smad4-reexpression in the cervical cancer cell line C4-II is associated with a gene expression profile that predicts a preferential role of Smad4 in extracellular matrix composition

scientific article

Identification of microRNAs in the cerebrospinal fluid as marker for primary diffuse large B-cell lymphoma of the central nervous system ⬇️

scientific article published on January 3, 2011

Immunoscreening of the extracellular proteome of colorectal cancer cells

scientific article

Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk

scientific article (publication date: 9 June 2005)

Keratin 23, a novel DPC4/Smad4 target gene which binds 14-3-3ε. ⬇️

scientific article

Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report

scientific article published on 28 February 2019

Levothyroxine therapy and impaired clearance are the strongest contributors to small intestinal bacterial overgrowth: Results of a retrospective cohort study.

scientific article published on February 2017

Loss of Smad4 correlates with loss of the invasion suppressor E-cadherin in advanced colorectal carcinomas

scientific article published in April 2004

MiR-30a-5p suppresses tumor growth in colon carcinoma by targeting DTL.

scientific article published on 27 January 2012

No Difference in Colorectal Cancer Incidence or Stage at Detection by Colonoscopy Among 3 Countries With Different Lynch Syndrome Surveillance Policies

scientific article published on 29 July 2018

Peri-operative chemotherapy for the treatment of resectable liver metastases from colorectal cancer: A systematic review and meta-analysis of randomized trials

scientific article

Prognostic Value of Reduced SMAD4 Expression in Patients With Metastatic Colorectal Cancer Under Oxaliplatin-Containing Chemotherapy: A Translational Study of the AIO Colorectal Study Group ⬇️

scientific article published on March 1, 2011

Risk-Reducing Gynecological Surgery in Lynch Syndrome: Results of an International Survey from the Prospective Lynch Syndrome Database

scientific article published on 18 July 2020

Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report

scientific article published on 01 December 2020

Risks of less common cancers in proven mutation carriers with lynch syndrome

scientific article published on 22 October 2012

Role of CT colonography in colorectal cancer screening: risks and benefits

scientific article published on May 2010

SMAD4 mediates mesenchymal-epithelial reversion in SW480 colon carcinoma cells

scientific article published on July 1, 2010

Similar Adenoma Detection Rates in Colonoscopic Procedures of Patients with Spinal Cord Injury Compared to Controls

scientific article published on 29 August 2019

Smad4 deficiency in cervical carcinoma cells.

scientific article

Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells

scientific article published on 01 September 2002

Smad4 transcriptional pathways and angiogenesis

scientific article

The future role of the gastroenterologist in digestive oncology: an international perspective

scientific article published on 24 August 2011

The influence of 5-aminosalicylic acid on the progression of colorectal adenomas via the ss-catenin signaling pathway ⬇️

scientific article published on December 22, 2011

The patient with multiple intestinal polyps

scientific article published on January 2007

Treatment sequence of synchronously (liver) metastasized colon cancer

scientific article

Truncating mutations in Peutz-Jeghers syndrome are associated with more polyps, surgical interventions and cancers

scientific article published on 2 September 2009

Tumor suppressor Smad4 mediates downregulation of the anti-adhesive invasion-promoting matricellular protein SPARC: Landscaping activity of Smad4 as revealed by a "secretome" analysis.

scientific article

Uncoupled responses of Smad4-deficient cancer cells to TNFalpha result in secretion of monomeric laminin-gamma2

scientific article published on 22 March 2010

Value of upper GI endoscopy for gastric cancer surveillance in patients with Lynch syndrome

scientific article published on 15 September 2020

[Current recommendations for surveillance, risk reduction and therapy in Lynch syndrome patients]

scientific article published on 18 November 2019

[Gastrointestinal tumors--interdisciplinary discussion over new data].

scientific article published on 27 April 2011

aRNA-longSAGE: a new approach to generate SAGE libraries from microdissected cells

scientific article

ß-catenin, Cox-2 and p53 immunostaining in colorectal adenomas to predict recurrence after endoscopic polypectomy ⬇️

scientific article published on March 21, 2013

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