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List of works by Peter Libby

18F-4V for PET-CT imaging of VCAM-1 expression in atherosclerosis

scientific article published on October 2009

A Rock and a Hard Place: Chiseling Away at the Multiple Mechanisms of Aortic Stenosis.

scientific article

A fluorescent probe for the detection of myeloperoxidase activity in atherosclerosis-associated macrophages

scientific article published on November 2007

A guanidine‐rich regulatory oligodeoxynucleotide improves type‐2 diabetes in obese mice by blocking T‐cell differentiation ⬇️

scientific article published on October 1, 2012

A guiding map for inflammation

scientific article published on July 2017

A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense

scientific article

A new opening on aortic stenosis: predicting prognosis with clonal haematopoiesis

scientific article published on 01 February 2020

A novel prostaglandin E receptor 4-associated protein participates in antiinflammatory signaling

scientific article

A randomized trial of rosuvastatin in the prevention of venous thromboembolism

scientific article published on 29 March 2009

A winter's tale: report from the First Annual Canadian Biomarkers and Surrogate Endpoints Symposium

scientific article published on September 2009

AGE-BSA decreases ABCG1 expression and reduces macrophage cholesterol efflux to HDL

scientific article published on 26 September 2006

Activatable magnetic resonance imaging agent reports myeloperoxidase activity in healing infarcts and noninvasively detects the antiinflammatory effects of atorvastatin on ischemia-reperfusion injury.

scientific article published on 11 February 2008

Activation of prostaglandin E2-EP4 signaling reduces chemokine production in adipose tissue

scientific article

Activation of smooth muscle and endothelial cells following balloon injury

scientific article published on 01 January 1995

Acute Coronary Syndromes: The Way Forward From Mechanisms to Precision Treatment

scientific article published in September 2017

Acute pancreatitis with long-term celecoxib vs. ibuprofen or naproxen: data from the PRECISION trial

scientific article published on 13 March 2018

Adaptive immunity and atherosclerosis

scientific article published on 26 July 2009

Adaptive immunity in acute coronary syndromes: chicken or egg?

scientific article

Adipocytes promote interleukin-18 binding to its receptors during abdominal aortic aneurysm formation in mice

scientific article published on 10 December 2019

Adiponectin Induces Pro-inflammatory Programs in Human Macrophages and CD4+ T Cells ⬇️

scientific article published on September 4, 2012

Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling

scientific article published on 23 January 2009

Adiponectin inhibits allograft rejection in murine cardiac transplantation

scientific article published on October 2009

Adiponectin inhibits macrophage tissue factor, a key trigger of thrombosis in disrupted atherosclerotic plaques ⬇️

scientific article published on December 25, 2012

Adiponectin inhibits pro-inflammatory signaling in human macrophages independent of interleukin-10

scientific article published on 18 July 2009

Adiponectin inhibits the production of CXC receptor 3 chemokine ligands in macrophages and reduces T-lymphocyte recruitment in atherogenesis

scientific article published on 8 November 2007

Adiponectin: a key adipocytokine in metabolic syndrome

scientific article

All roads lead to IL-6: A central hub of cardiometabolic signaling

scientific article published on 01 May 2018

Allergic lung inflammation promotes atherosclerosis in apolipoprotein E-deficient mice

scientific article published on February 2016

Angiotensin II-induced TLR4 mediated abdominal aortic aneurysm in apolipoprotein E knockout mice is dependent on STAT3.

scientific article published on 20 August 2015

Angiotensin induces inflammatory activation of human vascular smooth muscle cells

scientific article published on 01 July 1999

Angiotensin type 2 receptor is expressed in murine atherosclerotic lesions and modulates lesion evolution

scientific article

Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis

scientific article published on 16 September 2020

Anti-Inflammatory Therapy With Canakinumab for the Prevention of Hospitalization for Heart Failure

scientific article published on 01 March 2019

Anti-Inflammatory Therapy with Canakinumab for the Prevention and Management of Diabetes

scientific article published on 3 March 2018

Anti-inflammation Therapy by Activation of Prostaglandin EP4 Receptor in Cardiovascular and Other Inflammatory Diseases ⬇️

scientific article published on February 1, 2012

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

scientific article published on 27 August 2017

Apolipoprotein CIII in apolipoprotein B lipoproteins enhances the adhesion of human monocytic cells to endothelial cells

scientific article published on February 2006

Apolipoprotein CIII induces expression of vascular cell adhesion molecule-1 in vascular endothelial cells and increases adhesion of monocytic cells

scientific article published on 7 August 2006

Apolipoprotein CIII-induced THP-1 cell adhesion to endothelial cells involves pertussis toxin-sensitive G protein- and protein kinase C alpha-mediated nuclear factor-kappaB activation

scientific article published on 12 October 2006

Apoptosis of vascular smooth muscle cells induced by in vitro stimulation with interferon-gamma, tumor necrosis factor-alpha, and interleukin-1 beta

scientific article published on 01 January 1996

Arterial and aortic valve calcification abolished by elastolytic cathepsin S deficiency in chronic renal disease.

scientific article published on 23 March 2009

Assisted Living in the Atheroma: Elderly Macrophages Promote Plaques

scientific article published in December 2016

Associations between soluble CD40 ligand, atherosclerosis risk factors, and subclinical atherosclerosis: results from the Dallas Heart Study

scientific article published on 18 August 2005

Atherogenesis in mice does not require CD40 ligand from bone marrow-derived cells

scientific article published on 03 March 2005

Atheroma Susceptible to Thrombosis Exhibit Impaired Endothelial Permeability In Vivo as Assessed by Nanoparticle-Based Fluorescence Molecular Imaging

scientific article

Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression

scientific article published on 18 February 2016

Atherosclerosis and proteinase activation

scientific article

Atherosclerosis: Successes, Surprises, and Future Challenges

scientific article published on February 2016

Atherosclerosis: disease biology affecting the coronary vasculature

scientific article published on 23 October 2006

Atherosclerosis: the new view

scientific article (publication date: May 2002)

Atherosclerosis: the path from genomics to therapeutics

scientific article published on 2 April 2007

Atherosclerotic Vascular Disease Conference: Writing Group III: pathophysiology

scientific article published on June 2004

Atherosclerotic plaque inflammation: the final frontier?

scientific article published on May 2004

Atorvastatin Reduces In Vivo Fibrin Deposition and Macrophage Accumulation, and Improves Primary Patency Duration and Maturation of Murine Arteriovenous Fistula

scientific article published on 09 March 2020

Augmented expression and activity of extracellular matrix-degrading enzymes in regions of low endothelial shear stress colocalize with coronary atheromata with thin fibrous caps in pigs

scientific article published on 31 January 2011

Augmented expression of cyclooxygenase-2 in human atherosclerotic lesions

scientific article published on October 1999

Author Correction: A guiding map for inflammation

scientific article published on 07 December 2020

Author Correction: Clonal haematopoiesis: connecting ageing and inflammation in cardiovascular disease

scientific article published on 02 July 2020

B7-1/B7-2 costimulation regulates plaque antigen-specific T-cell responses and atherogenesis in low-density lipoprotein receptor-deficient mice

scientific article published on 19 April 2004

Baseline characteristics of participants in the JUPITER trial, a randomized placebo-controlled primary prevention trial of statin therapy among individuals with low low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein

scientific article published on 24 October 2007

Binding of CD40L to Mac-1's I-domain involves the EQLKKSKTL motif and mediates leukocyte recruitment and atherosclerosis--but does not affect immunity and thrombosis in mice

scientific article published on 13 October 2011

Biomarkers: A Challenging Conundrum in Cardiovascular Disease

scientific article

Bone Marrow Endothelial Cells Regulate Myelopoiesis in Diabetes

scientific article published on 22 April 2020

C-peptide colocalizes with macrophages in early arteriosclerotic lesions of diabetic subjects and induces monocyte chemotaxis in vitro

scientific article

C-reactive protein induces matrix metalloproteinase-1 and -10 in human endothelial cells: implications for clinical and subclinical atherosclerosis.

scientific article

C-reactive protein, but not low-density lipoprotein cholesterol levels, associate with coronary atheroma regression and cardiovascular events after maximally intensive statin therapy

scientific article published on 16 September 2013

CADASIL mutations impair Notch3 glycosylation by Fringe

scientific article published on 27 April 2005

CC chemokine receptor-1 activates intimal smooth muscle-like cells in graft arterial disease

scientific article

CD1 expression in human atherosclerosis. A potential mechanism for T cell activation by foam cells

scientific article published on September 1999

CD11c(+) dendritic cells maintain antigen processing, presentation capabilities, and CD4(+) T-cell priming efficacy under hypercholesterolemic conditions associated with atherosclerosis

scientific article published on 2 October 2008

CD154 (CD40 ligand)

scientific article published on 01 July 2000

CD40 ligand mediates inflammation independently of CD40 by interaction with Mac-1.

scientific article published on 19 March 2007

CD40 ligation induces tissue factor expression in human vascular smooth muscle cells

scientific article published on January 2000

CD40L induces inflammation and adipogenesis in adipose cells--a potential link between metabolic and cardiovascular disease

scientific article published on 19 February 2010

CD74 Deficiency Mitigates Systemic Lupus Erythematosus-like Autoimmunity and Pathological Findings in Mice.

scientific article published on 20 February 2017

CDC/AHA Workshop on Markers of Inflammation and Cardiovascular Disease

article

CHIP (Clonal Hematopoiesis of Indeterminate Potential)

scientific article published on 01 August 2018

COVID-19 - A Vascular Disease

scientific article published on 14 October 2020

CXCR3 controls T-cell accumulation in fat inflammation

scientific article

Cardiovascular Benefits of GLP-1 Receptor Agonism: Is Inflammation a Key?

Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis

scientific article

Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from the JUPITER trial ⬇️

scientific article published on August 11, 2012

Cardiovascular disease in patients with chronic inflammation: mechanisms underlying premature cardiovascular events in rheumatologic conditions

scientific article

Cardiovascular drug development: is it dead or just hibernating?

scientific article published on April 2015

Cardiovascular remodelling in coronary artery disease and heart failure

scientific article

Cathepsin G activity lowers plasma LDL and reduces atherosclerosis

scientific article (publication date: November 2014)

Cathepsin G deficiency reduces periaortic calcium chloride injury-induced abdominal aortic aneurysms in mice

scientific article

Cathepsin K Deficiency Ameliorates Systemic Lupus Erythematosus-like Manifestations in Faslpr Mice.

scientific article published on 16 January 2017

Cathepsin K Deficiency Reduces Elastase Perfusion–Induced Abdominal Aortic Aneurysms in Mice ⬇️

scientific article published on August 4, 2011

Cathepsin L activity controls adipogenesis and glucose tolerance

scientific article

Cathepsin L activity is essential to elastase perfusion-induced abdominal aortic aneurysms in mice

scientific article published in November 2011

Cathepsin L deficiency reduces diet-induced atherosclerosis in low-density lipoprotein receptor-knockout mice.

scientific article

Cathepsin L expression and regulation in human abdominal aortic aneurysm, atherosclerosis, and vascular cells

scientific article published on 27 June 2005

Cathepsin L-selective inhibitors: A potentially promising treatment for COVID-19 patients

scientific article published on 26 May 2020

Cathepsin S-mediated fibroblast trans-differentiation contributes to left ventricular remodelling after myocardial infarction ⬇️

scientific article published on June 14, 2013

Characterization of human atherosclerotic plaques by intravascular magnetic resonance imaging

scientific article published on 03 October 2005

Characterization of smooth muscle-like cells in circulating human peripheral blood

scientific article published on 25 October 2005

Chlamydia pneumoniae as an emerging risk factor in cardiovascular disease

scientific article

Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages

scientific article

Cholesterol and atherosclerosis

scientific article

Chronic variable stress activates hematopoietic stem cells

scientific article

Circumferential stress and matrix metalloproteinase 1 in human coronary atherosclerosis. Implications for plaque rupture

scientific article published on 01 August 1996

Clonal Hematopoiesis Confers Predisposition to Both Cardiovascular Disease and Cancer: A Newly Recognized Link Between Two Major Killers

scientific article published on 29 May 2018

Clonal haematopoiesis: connecting ageing and inflammation in cardiovascular disease

scientific article published on 12 August 2019

Coinhibitory suppression of T cell activation by CD40 protects against obesity and adipose tissue inflammation in mice

scientific article published on 24 March 2014

Cold ischemia induces isograft arteriopathy, but does not augment allograft arteriopathy in non-immunosuppressed hosts

scientific article published on March 2002

Collagenases and cracks in the plaque

scientific article published on August 2013

Colony stimulating factor-1 producing endothelial cells and mesenchymal stromal cells maintain monocytes within a perivascular bone marrow niche

scientific article published in 2022

Combined non-invasive assessment of endothelial shear stress and molecular imaging of inflammation for the prediction of inflamed plaque in hyperlipidaemic rabbit aortas

scientific article published on 24 March 2016

Coronary Artery Calcification: Current Concepts and Clinical Implications

Coronary Plaque Microstructure and Composition Modify Optical Polarization: A New Endogenous Contrast Mechanism for Optical Frequency Domain Imaging

scientific article published on 9 December 2017

Coronary atheroma volume and cardiovascular events during maximally intensive statin therapy

scientific article published on 25 July 2013

Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation

scientific article published on 31 August 2009

Cystatin C deficiency increases elastic lamina degradation and aortic dilatation in apolipoprotein E-null mice

scientific article published on 13 January 2005

Cystatin C deficiency promotes inflammation in angiotensin II-induced abdominal aortic aneurisms in atherosclerotic mice

scientific article

Cysteine protease cathepsins in cardiovascular disease: from basic research to clinical trials

scientific article published on 20 April 2018

Cytokines in the pathogenesis of atherosclerosis

scientific article published on 01 October 2002

Cytokines induce indoleamine 2,3-dioxygenase expression in human atheroma-asociated cells: implications for persistent Chlamydophila pneumoniae infection

scientific article published on July 2002

Cytokines score a knockout. Harnessing gene targeting to gain insight into the pathogenesis of myocarditis

scientific article published on 01 February 1997

Deficiencies of IL-4 or TNF-alpha receptor-1 do not diminish graft arteriosclerosis in cardiac allografts

scientific article published on 01 February 1999

Deficiency of FcϵR1 Increases Body Weight Gain but Improves Glucose Tolerance in Diet-Induced Obese Mice.

scientific article

Deficiency of antigen-presenting cell invariant chain reduces atherosclerosis in mice

scientific article

Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice

scientific article

Deficiency of mouse mast cell protease 4 mitigates cardiac dysfunctions in mice after myocardium infarction

scientific article published on 11 January 2019

Deficiency of the cysteine protease cathepsin S impairs microvessel growth

scientific article published on 6 February 2003

Deletion of EP4 on Bone Marrow–Derived Cells Enhances Inflammation and Angiotensin II–Induced Abdominal Aortic Aneurysm Formation ⬇️

scientific article published on November 18, 2010

Deletion of the phosphoinositide 3-kinase p110gamma gene attenuates murine atherosclerosis

scholarly article

Diabetes and atherosclerosis: epidemiology, pathophysiology, and management

scientific article

Diabetic macrovascular disease: the glucose paradox?

scientific article

Dietary cholesterol is essential to mast cell activation and associated obesity and diabetes in mice

scientific article published on 09 April 2019

Differences in Safety of Non-Steroidal Anti-Inflammatory Drugs in Patients with Osteoarthritis and Rheumatoid Arthritis: A Randomized Clinical Trial

scientific article

Differential Roles of Cysteinyl Cathepsins in TGF-β Signaling and Tissue Fibrosis

scientific article published on 09 August 2019

Differential blood pressure effects of ibuprofen, naproxen, and celecoxib in patients with arthritis: the PRECISION-ABPM (Prospective Randomized Evaluation of Celecoxib Integrated Safety Versus Ibuprofen or Naproxen Ambulatory Blood Pressure Measure

scientific article

Differential expression of the IFN-gamma-inducible CXCR3-binding chemokines, IFN-inducible protein 10, monokine induced by IFN, and IFN-inducible T cell alpha chemoattractant in human cardiac allografts: association with cardiac allograft vasculopat

scientific article published on 01 August 2002

Differential expression of three T lymphocyte-activating CXC chemokines by human atheroma-associated cells

scientific article

Direct Anti-Inflammatory Mechanisms Contribute to Attenuation of Experimental Allograft Arteriosclerosis by Statins ⬇️

scientific article published on September 29, 2003

Distinct CSF1 Micro-Environments Maintain Monocytes within a Perivascular Bone Marrow Niche

scientific article published on 27 May 2020

Diversity of denizens of the atherosclerotic plaque: not all monocytes are created equal

scientific article published on 01 June 2008

Do patients benefit from omega-3 fatty acids?

EP4 Receptor-Associated Protein in Macrophages Ameliorates Colitis and Colitis-Associated Tumorigenesis

scientific article published on 6 October 2015

Editorial commentary: Arson in the artery: Who set the atheroma aflame?

scientific article published on 28 March 2019

Effect of Aspirin Coadministration on the Safety of Celecoxib, Naproxen, or Ibuprofen

scientific article published in April 2018

Effect of a cleavage-resistant collagen mutation on left ventricular remodeling.

scientific article

Effect of antihypertensive agents on cardiovascular events in patients with coronary disease and normal blood pressure: the CAMELOT study: a randomized controlled trial

scientific article

Effect of atorvastatin on risk of recurrent cardiovascular events after an acute coronary syndrome associated with high soluble CD40 ligand in the Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) Study

scientific article published on 19 July 2004

Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial

scientific article published on 25 August 2017

Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial

scientific article

Effects of Interleukin-1β Inhibition on Blood Pressure, Incident Hypertension, and Residual Inflammatory Risk: A Secondary Analysis of CANTOS

scientific article published on 30 December 2019

Effects of Interleukin-1β Inhibition on Incident Anemia: Exploratory Analyses From a Randomized Trial

scientific article published on 24 March 2020

Effects of interleukin-1β inhibition with canakinumab on hemoglobin A1c, lipids, C-reactive protein, interleukin-6, and fibrinogen: a phase IIb randomized, placebo-controlled trial

scientific article published on 5 November 2012

Effects of statins in reducing thrombotic risk and modulating plaque vulnerability.

scientific article

Elastogenesis in human arterial disease: a role for macrophages in disordered elastin synthesis

scientific article

Elevated plasma levels of the atherogenic mediator soluble CD40 ligand in diabetic patients: a novel target of thiazolidinediones

scientific article published on 12 May 2003

Elevated release of sCD40L from platelets of diabetic patients by thrombin, glucose and advanced glycation end products

scientific article published in May 2005

Elevations in neutrophils with obstructive sleep apnea: The Multi-Ethnic Study of Atherosclerosis (MESA).

scientific article published in April 2018

Endogenous tissue plasminogen activator and risk of recurrent cardiac events after an acute coronary syndrome in the MIRACL study.

scientific article published on 26 March 2009

Endothelial activation potentiates neointimal lesion formation in the rabbit aorta after balloon injury

scientific article published on 01 April 1997

Endothelial and smooth muscle cells express leukocyte adhesion molecules heterogeneously during acute rejection of rabbit cardiac allografts.

scientific article published in May 1994

Endotoxinemia Accelerates Atherosclerosis via Electrostatic Charge-Mediated Monocyte Adhesion

scientific article published on 10 November 2020

Enhanced expression of CD44 variants in human atheroma and abdominal aortic aneurysm: possible role for a feedback loop in endothelial cells

scientific article

Essential role for Smad3 in regulating MCP-1 expression and vascular inflammation

scientific article published on 29 January 2004

Evidence for altered balance between matrix metalloproteinases and their inhibitors in human aortic diseases

scientific article published on 01 January 1997

Examining the dyslipidemia constellation: an interactive forum on new treatment advances. Introduction

scientific article published in March 2004

Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells

scientific article published on 07 November 2019

Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for atherogenesis

scientific article published on January 2002

Expression of stromelysin-3 in atherosclerotic lesions: regulation via CD40-CD40 ligand signaling in vitro and in vivo

scientific article

Expression of tissue inhibitor of metalloproteinases-3 in human atheroma and regulation in lesion-associated cells: a potential protective mechanism in plaque stability

scientific article published on 01 August 1998

Extramedullary hematopoiesis generates Ly-6C(high) monocytes that infiltrate atherosclerotic lesions

scientific article published on 5 December 2011

Factors underlying regression of coronary atheroma with potent statin therapy

scientific article published on 3 May 2013

Fanning the flames: inflammation in cardiovascular diseases

scientific article published on 29 June 2015

Fish oil and post-operative atrial fibrillation: a meta-analysis of randomized controlled trials

scientific article

Fish oil and postoperative atrial fibrillation: the Omega-3 Fatty Acids for Prevention of Post-operative Atrial Fibrillation (OPERA) randomized trial

scientific article published on November 2012

Flow Perturbation Mediates Neutrophil Recruitment and Potentiates Endothelial Injury via TLR2 in Mice: Implications for Superficial Erosion.

scientific article published on 20 April 2017

Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K.

scientific article published on 2 January 2009

From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I.

scientific article published on October 2003

From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II.

scientific article published on October 2003

Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosis

scientific article

Fundamental Cardiovascular Research: Returns on Societal Investment: A Scientific Statement From the American Heart Association

scientific article

Genesis and growth of extracellular-vesicle-derived microcalcification in atherosclerotic plaques

scientific article

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

scientific article published on 26 July 2009

Genetically determined resistance to collagenase action augments interstitial collagen accumulation in atherosclerotic plaques.

scientific article

Genetically engineered resistance for MMP collagenases promotes abdominal aortic aneurysm formation in mice infused with angiotensin II

scientific article

Genetically programmed biases in Th1 and Th2 immune responses modulate atherogenesis

scientific article published on 8 May 2008

Glycated LDL increases monocyte CC chemokine receptor 2 expression and monocyte chemoattractant protein-1-mediated chemotaxis

scientific article published on 27 December 2007

Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease

scientific article published on 30 January 2019

HDL cholesterol and residual risk of first cardiovascular events after treatment with potent statin therapy: an analysis from the JUPITER trial

scientific article published on 23 July 2010

HMG CoA reductase inhibitors reduce plasminogen activator inhibitor-1 expression by human vascular smooth muscle and endothelial cells

scientific article published on 01 February 2000

High-dose atorvastatin enhances the decline in inflammatory markers in patients with acute coronary syndromes in the MIRACL study

scientific article published on 15 September 2003

High-resolution magnetic resonance imaging enhanced with superparamagnetic nanoparticles measures macrophage burden in atherosclerosis

scientific article

Highlights of 10 years of immunology in Nature Reviews Immunology

scientific article published on 23 September 2011

Host CD40 ligand deficiency induces long-term allograft survival and donor-specific tolerance in mouse cardiac transplantation but does not prevent graft arteriosclerosis

scientific article published on 01 September 2000

How does lipid lowering prevent coronary events? New insights from human imaging trials

scientific article published on 8 January 2015

Hypochlorous acid, a macrophage product, induces endothelial apoptosis and tissue factor expression: involvement of myeloperoxidase-mediated oxidant in plaque erosion and thrombogenesis

scientific article

Hypoxia but not inflammation augments glucose uptake in human macrophages: Implications for imaging atherosclerosis with 18fluorine-labeled 2-deoxy-D-glucose positron emission tomography

scientific article published in August 2011

Identification of splenic reservoir monocytes and their deployment to inflammatory sites

scientific article

Identifying patients at high risk of a cardiovascular event in the near future: current status and future directions: report of a national heart, lung, and blood institute working group

scientific article

IgE actions on CD4+ T cells, mast cells, and macrophages participate in the pathogenesis of experimental abdominal aortic aneurysms

scientific article

IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe-/- mice

scientific article published on 01 November 2018

IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe–/– mice ⬇️

scientific article published on August 8, 2011

Imaging Granzyme B Activity Assesses Immune-Mediated Myocarditis

scientific article

Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis

scientific article

Immune effector mechanisms implicated in atherosclerosis: from mice to humans

scientific article published on June 2013

Immunometabolism and atherosclerosis: perspectives and clinical significance: a position paper from the Working Group on Atherosclerosis and Vascular Biology of the European Society of Cardiology

scientific article published on 01 July 2019

Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis.

scientific article

Improved characterization of atherosclerotic plaques by gadolinium contrast during intravascular magnetic resonance imaging of human arteries

scientific article published on 27 March 2007

In vivo nanoparticle assessment of pathological endothelium predicts the development of inflow stenosis in murine arteriovenous fistula

scientific article

In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing.

scientific article published on 18 December 2013

Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques

scientific article

Increased glucose uptake in visceral versus subcutaneous adipose tissue revealed by PET imaging

scientific article

Increased intermediate CD14++CD16++ monocyte subset levels associate with restenosis after peripheral percutaneous transluminal angioplasty

scientific article published on 2 September 2016

Increased microvascularization and vessel permeability associate with active inflammation in human atheromata

scientific article

Increased plasma oxidized phospholipid:apolipoprotein B-100 ratio with concomitant depletion of oxidized phospholipids from atherosclerotic lesions after dietary lipid-lowering: a potential biomarker of early atherosclerosis regression.

scientific article published on 2 November 2006

Indocyanine green enables near-infrared fluorescence imaging of lipid-rich, inflamed atherosclerotic plaques

scientific article

Induction of DNA synthesis by a single transient mechanical stimulus of human vascular smooth muscle cells. Role of fibroblast growth factor-2

scientific article published on 01 January 1996

Induction of endothelial-leukocyte interaction by interferon-gamma requires coactivation of nuclear factor-kappaB

article by R De Caterina et al published 1 February 2001 in Arteriosclerosis, Thrombosis, and Vascular Biology

Induction of tissue factor expression in human endothelial cells by CD40 ligand is mediated via activator protein 1, nuclear factor kappa B, and Egr-1.

scientific article

Inflamm-ageing: the role of inflammation in age-dependent cardiovascular disease

scientific article published on 01 February 2020

Inflammation and atherosclerosis: role of C-reactive protein in risk assessment

scientific article published on March 2004

Inflammation and cardiovascular disease mechanisms

scientific article

Inflammation and cellular immune responses in abdominal aortic aneurysms

scientific article

Inflammation and immunity in diseases of the arterial tree: players and layers

scientific article

Inflammation and its resolution as determinants of acute coronary syndromes

scientific article

Inflammation and the pathogenesis of atherosclerosis

Inflammation and thrombosis - testing the hypothesis with anti-inflammatory drug trials

scientific article published on 18 August 2016

Inflammation in Atherosclerosis ⬇️

scientific article published on September 1, 2012

Inflammation in atherosclerosis: from pathophysiology to practice

scientific article

Inflammation in atherosclerosis: from vascular biology to biomarker discovery and risk prediction

scientific article published on January 2008

Inflammation in atherosclerosis: transition from theory to practice

scientific article published on 09 January 2010

Inflammation in atherosclerosis: visualizing matrix metalloproteinase action in macrophages in vivo

scientific article published on 26 June 2006

Inflammation in diabetes mellitus: role of peroxisome proliferator-activated receptor-alpha and peroxisome proliferator-activated receptor-gamma agonists

scientific article published on 22 December 2006

Inflammation, Immunity, and Infection in Atherothrombosis: JACC Review Topic of the Week

Inflammation, immunity, and HMG-CoA reductase inhibitors: statins as antiinflammatory agents?

scientific article published on June 2004

Inflammation, statin therapy, and risk of stroke after an acute coronary syndrome in the MIRACL study

scientific article

Inflammatory Biomarkers, Death, and Recurrent Nonfatal Coronary Events After an Acute Coronary Syndrome in the MIRACL Study ⬇️

scientific article published on January 28, 2013

Inflammatory mechanisms: the molecular basis of inflammation and disease

scientific article published on December 2007

Influence of Helicobacter pylori Infection During Atherogenesis In Vivo in Mice ⬇️

scientific article published on January 11, 2002

Influence of pre-analytical and analytical factors on soluble CD40L measurements

scientific article published on 01 November 2006

Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice

scientific article

Inhibition of Interleukin-1β and Reduction in Atherothrombotic Cardiovascular Events in the CANTOS Trial

scientific article published on 01 October 2020

Inhibition of Interleukin-1β by Canakinumab and Cardiovascular Outcomes in Patients With Chronic Kidney Disease

scientific article published on 01 May 2018

Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment

scientific article published on 01 July 2005

Innate and adaptive immunity in atherosclerosis

scientific article

Innate and adaptive immunity in the pathogenesis of atherosclerosis

scientific article

Innate response activator B cells aggravate atherosclerosis by stimulating T helper-1 adaptive immunity

scientific article

Interaction of the allogeneic state and hypercholesterolemia in arterial lesion formation in experimental cardiac allografts

scientific article published on 01 May 1994

Interferon-gamma, a Th1 cytokine, regulates fat inflammation: a role for adaptive immunity in obesity

scientific article published on 24 July 2008

Interferon-γ Released by Activated CD8+ T Lymphocytes Impairs the Calcium Resorption Potential of Osteoclasts in Calcified Human Aortic Valves.

scientific article published on 18 April 2017

Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter

scientific journal article

Interleukin-1 Beta as a Target for Atherosclerosis Therapy: Biological Basis of CANTOS and Beyond

scientific article

Interleukin-10 (IL-10) augments allograft arterial disease: paradoxical effects of IL-10 in vivo

scientific article published on December 1999

Interleukin-18, the metabolic syndrome, and subclinical atherosclerosis: results from the Dallas Heart Study.

scientific article published on 12 July 2007

Interleukin-1β Mediates Arterial Thrombus Formation via NET-Associated Tissue Factor

scientific article published on 26 November 2019

Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: Rationale and Design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS) ⬇️

scientific article published on September 14, 2011

Internal Bleeding: Is Intraplaque Hemorrhage a Decoration or a Driver?

article published in 2018

Intertwining of thrombosis and inflammation in atherosclerosis

scientific article published on January 2007

Jak-ing Up the Plaque's Lipid Core…and Even More

scientific article published on 01 November 2018

Kruppel-like factor KLF10 targets transforming growth factor-beta1 to regulate CD4(+)CD25(-) T cells and T regulatory cells

scientific article published on 14 July 2009

Lack of EP4 receptors on bone marrow-derived cells enhances inflammation in atherosclerotic lesions ⬇️

scientific article published on August 24, 2010

Leptin Deficiency Shifts Mast Cells toward Anti-Inflammatory Actions and Protects Mice from Obesity and Diabetes by Polarizing M2 Macrophages

scientific article

Leukocyte integrin Mac-1 promotes acute cardiac allograft rejection

scientific article published on 31 March 2008

Leukocytes Link Local and Systemic Inflammation in Ischemic Cardiovascular Disease: An Expanded "Cardiovascular Continuum".

scientific article published on March 2016

Liberation of desmosine and isodesmosine as amino acids from insoluble elastin by elastolytic proteases ⬇️

scientific article published on June 25, 2011

Linking regulation of nitric oxide to endothelin-1: The Yin and Yang of vascular tone in the atherosclerotic plaque

scientific article published on 14 November 2019

Lipid lowering reduces oxidative stress and endothelial cell activation in rabbit atheroma

scientific article

Lipid lowering therapy in atherosclerosis

scientific article

LncRNA VINAS regulates atherosclerosis by modulating NF-κB and MAPK signaling

scientific article published on 06 October 2020

Local cytokine environments drive aneurysm formation in allografted aortas

scientific article

Local proliferation dominates lesional macrophage accumulation in atherosclerosis

scientific article published on 11 August 2013

Long noncoding RNA SNHG12 integrates a DNA-PK-mediated DNA damage response and vascular senescence

scientific article published on 01 February 2020

Loss of myeloid related protein-8/14 exacerbates cardiac allograft rejection

scientific article published on 5 December 2011

Loss-of-Function Mutations in Dnmt3a and Tet2 Lead to Accelerated Atherosclerosis and Convergent Macrophage Phenotypes in Mice ⬇️

scholarly article

Low-Dose Methotrexate for the Prevention of Atherosclerotic Events

scientific article published on 10 November 2018

Lp-PLA2 Antagonizes Left Ventricular Healing After Myocardial Infarction by Impairing the Appearance of Reparative Macrophages

scientific article

Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata

scientific article

Ly-6Chigh monocytes depend on Nr4a1 to balance both inflammatory and reparative phases in the infarcted myocardium

scientific article

Lysosomal cysteine proteases in atherosclerosis

scientific article published on 3 June 2004

MRI of rabbit atherosclerosis in response to dietary cholesterol lowering

scientific article published on 01 August 1999

Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases

scientific article

Macrophage migration inhibitory factor deficiency impairs atherosclerosis in low-density lipoprotein receptor-deficient mice

scientific article

Macrophage migration inhibitory factor is associated with aneurysmal expansion

scientific article published in March 2003

Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes

scientific article

Macrophage-derived matrix vesicles: an alternative novel mechanism for microcalcification in atherosclerotic plaques

scientific article published on 24 April 2013

Macrophages Facilitate Electrical Conduction in the Heart.

scientific article published in April 2017

Macrophages in human atheroma contain PPARgamma: differentiation-dependent peroxisomal proliferator-activated receptor gamma(PPARgamma) expression and reduction of MMP-9 activity through PPARgamma activation in mononuclear phagocytes in vitro

scientific article published on July 1998

Macrophages retain hematopoietic stem cells in the spleen via VCAM-1

scientific article

Mast cell tryptase deficiency attenuates mouse abdominal aortic aneurysm formation

scientific article published on 14 April 2011

Mast cells as mediators and modulators of atherogenesis

scientific article published on 01 May 2007

Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice

scientific article

Mast cells promote atherosclerosis by releasing proinflammatory cytokines

scientific article published on 03 June 2007

Matrix metalloproteinase-13 predominates over matrix metalloproteinase-8 as the functional interstitial collagenase in mouse atheromata.

scientific article

Matrix metalloproteinase-13/collagenase-3 deletion promotes collagen accumulation and organization in mouse atherosclerotic plaques

scientific article published on 17 October 2005

Matrix-metalloproteinase-14 deficiency in bone-marrow-derived cells promotes collagen accumulation in mouse atherosclerotic plaques

scientific article published on 4 February 2008

Mechanical strain tightly controls fibroblast growth factor-2 release from cultured human vascular smooth muscle cells

scientific article published on 01 January 1997

Mechanisms of Acute Coronary Syndromes and Their Implications for Therapy ⬇️

scientific article published on May 23, 2013

Mechanisms of Myeloid Cell Modulation of Atherosclerosis

scientific article published on August 2016

Mechanisms of Plaque Progression and Complications

Mechanisms of erosion of atherosclerotic plaques.

scientific article

Mechanisms of plaque stabilization with statins

scientific article

Metformin inhibits proinflammatory responses and nuclear factor-kappaB in human vascular wall cells.

scientific article published on 29 December 2005

Microscopic localization of active proteases by in situ zymography: detection of matrix metalloproteinase activity in vascular tissue

scientific article published on 01 July 1995

Moderate hypoxia potentiates interleukin-1β production in activated human macrophages

scientific article

Modulation of the interleukin-6 signalling pathway and incidence rates of atherosclerotic events and all-cause mortality: analyses from the Canakinumab Anti-Inflammatory Thrombosis Outcomes Study (CANTOS)

scientific article published on 01 October 2018

Molecular Imaging of Atherosclerosis for Improving Diagnostic and Therapeutic Development ⬇️

scientific article published on July 6, 2012

Molecular and cellular imaging of atherosclerosis: emerging applications

scientific article

Molecular and cellular mechanisms of the thrombotic complications of atherosclerosis

scientific article published on 18 December 2008

Molecular imaging of atherosclerosis: a progress report

scientific article

Molecular imaging of cardiovascular disease

scientific article published in August 2007

Molecular imaging of innate immune cell function in transplant rejection

scientific article published on 30 March 2009

Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease

scholarly article

Monocyte heterogeneity in cardiovascular disease

scientific article

Monocyte subset dynamics in human atherosclerosis can be profiled with magnetic nano-sensors

scientific article

Mucosal administration of heat shock protein-65 decreases atherosclerosis and inflammation in aortic arch of low-density lipoprotein receptor-deficient mice

scientific article published in September 2002

Murine "model" monotheism: an iconoclast at the altar of mouse

scientific article published in November 2015

Myeloid-related protein 8/14 and the risk of cardiovascular death or myocardial infarction after an acute coronary syndrome in the Pravastatin or Atorvastatin Evaluation and Infection Therapy: Thrombolysis in Myocardial Infarction (PROVE IT-TIMI ...

scientific article

Myeloid-related protein-8/14 is critical for the biological response to vascular injury

scientific article

Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells

scientific article published on May 2015

Myocardial infarction accelerates atherosclerosis.

scientific article

Na+-H+ exchanger 1 determines atherosclerotic lesion acidification and promotes atherogenesis

scientific article published on 04 September 2019

Nanoparticle PET-CT detects rejection and immunomodulation in cardiac allografts

scientific article published on 14 June 2013

Nanoparticle PET-CT imaging of macrophages in inflammatory atherosclerosis.

scientific article published on 24 December 2007

Nanoparticles targeting extra domain B of fibronectin-specific to the atherosclerotic lesion types III, IV, and V-enhance plaque detection and cargo delivery

scientific article published on 15 November 2018

Neutrophil Extracellular Traps Induce Endothelial Cell Activation and Tissue Factor Production Through Interleukin-1α and Cathepsin G

scientific article published on 01 August 2018

Neutrophil elastase in human atherosclerotic plaques: production by macrophages

scientific article published on 27 May 2003

Nonculprit Plaque Characteristics in Patients With Acute Coronary Syndrome Caused by Plaque Erosion vs Plaque Rupture: A 3-Vessel Optical Coherence Tomography Study

scientific article published on 7 February 2018

Noninvasive in vivo imaging of monocyte trafficking to atherosclerotic lesions

scientific article

Noninvasive vascular cell adhesion molecule-1 imaging identifies inflammatory activation of cells in atherosclerosis

scientific article published on 25 September 2006

North American Thrombosis Forum, AF Action Initiative Consensus Document

scientific article published on May 2016

Novel Lesional Transcriptional Signature Separates Atherosclerosis With and Without Diabetes in Yorkshire Swine and Humans

scientific article published on 11 February 2021

Number needed to treat with rosuvastatin to prevent first cardiovascular events and death among men and women with low low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: justification for the use of statins in prev

scientific article published on 22 September 2009

Obesity, inflammation, and atherosclerosis

scientific article published on 28 April 2009

Optical Visualization of Cathepsin K Activity in Atherosclerosis With a Novel, Protease-Activatable Fluorescence Sensor

scientific article published on 09 April 2007

Optical and multimodality molecular imaging: insights into atherosclerosis

scientific article published on 09 April 2009

Over a hump for imaging atherosclerosis: nanobodies visualize vascular cell adhesion molecule-1 in inflamed plaque

scientific article published on 01 March 2012

Oxidative Stress Biomarkers and Incidence of Postoperative Atrial Fibrillation in the Omega-3 Fatty Acids for Prevention of Postoperative Atrial Fibrillation (OPERA) Trial

scientific article

Oxidized Low-Density Lipoprotein Induces Macrophage Production of Prothrombotic Microparticles

scientific article published on 31 July 2020

Oxidized low-density lipoprotein augments and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors limit CD40 and CD40L expression in human vascular cells

scientific article published on December 2002

PETER LIBBY, MD: A Conversation With the Editor ⬇️

scientific article published on June 5, 2012

PPAR activators as antiinflammatory mediators in human T lymphocytes: implications for atherosclerosis and transplantation-associated arteriosclerosis

scientific article

PPARalpha activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells

scientific article published on June 1999

PPARalpha activators inhibit tissue factor expression and activity in human monocytes

scientific article

PPARgamma activation in human endothelial cells increases plasminogen activator inhibitor type-1 expression: PPARgamma as a potential mediator in vascular disease

scientific article published on 01 March 1999

Paclitaxel Drug-Coated Balloon Angioplasty Suppresses Progression and Inflammation of Experimental Atherosclerosis in Rabbits

scientific article published on 10 June 2020

Pathophysiology of coronary artery disease

scientific article

Pathway-Specific Polygenic Risk Scores Identify Obstructive Sleep Apnea-Related Pathways Differentially Moderating Genetic Susceptibility to Coronary Artery Disease

Pattern of graft- and host-specific MHC class II expression in long-term murine cardiac allografts: origin of inflammatory and vascular wall cells

scientific article published on July 1998

Peroxisome proliferator-activated receptor gamma activators inhibit gene expression and migration in human vascular smooth muscle cells

scientific article published in November 1998

Peroxisome proliferator-activated receptor-gamma activators inhibit IFN-gamma-induced expression of the T cell-active CXC chemokines IP-10, Mig, and I-TAC in human endothelial cells

scientific article

Peroxisome proliferator-activated receptors (PPARs) and their role in the vessel wall: possible mediators of cardiovascular risk?

scientific article

Plaque erosion: a new in vivo diagnosis and a potential major shift in the management of patients with acute coronary syndromes

scientific article published on 9 January 2018

Plaque stabilization: Can we turn theory into evidence?

scientific article published on 2 October 2006

Plasma concentration of heat shock protein 27 and risk of cardiovascular disease: a prospective, nested case-control study

scientific article published on 16 November 2007

Plasma pentraxin 3 levels do not predict coronary events but reflect metabolic disorders in patients with coronary artery disease in the CARE trial

scientific article

Platelet expression profiling and clinical validation of myeloid-related protein-14 as a novel determinant of cardiovascular events

scientific article (publication date: 16 May 2006)

Pleiotropic Anti-atherosclerotic Effects of PCSK9 InhibitorsFrom Molecular Biology to Clinical Translation

scientific article published on 10 March 2018

Point-of-Care Technologies for Precision Cardiovascular Care and Clinical Research: National Heart, Lung, and Blood Institute Working Group

scientific article published on January 2016

Polymeric nanoparticle PET/MR imaging allows macrophage detection in atherosclerotic plaques

scientific article published on 8 January 2013

Premature Menopause, Clonal Hematopoiesis, and Coronary Artery Disease in Postmenopausal Women

scientific article published on 09 November 2020

Progression of atheroma: a struggle between death and procreation

scientific article

Proliferating arterial smooth muscle cells after balloon injury express TNF-alpha but not interleukin-1 or basic fibroblast growth factor

scientific article published on 01 January 1996

Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure.

scientific article published on 21 July 2016

Prostaglandin E receptor type 4-associated protein interacts directly with NF-kappaB1 and attenuates macrophage activation

scientific article

Prostaglandin E2 suppresses chemokine production in human macrophages through the EP4 receptor

scientific article

RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction.

scientific article published on June 2016

Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis

scientific article published on 2 January 2012

Rationale and design of the Cardiovascular Inflammation Reduction Trial: a test of the inflammatory hypothesis of atherothrombosis

scientific article published on 03 May 2013

Rationale and design of the Pemafibrate to Reduce Cardiovascular Outcomes by Reducing Triglycerides in Patients with Diabetes (PROMINENT) study

article

Rationale, design, and governance of Prospective Randomized Evaluation of Celecoxib Integrated Safety versus Ibuprofen Or Naproxen (PRECISION), a cardiovascular end point trial of nonsteroidal antiinflammatory agents in patients with arthritis

scientific article

Real-time catheter molecular sensing of inflammation in proteolytically active atherosclerosis

scientific article published on 13 October 2008

Reduced Nhe1 (Na+-H+ Exchanger-1) Function Protects ApoE-Deficient Mice From Ang II (Angiotensin II)-Induced Abdominal Aortic Aneurysms

scientific article published on 01 June 2020

Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial

scientific article published on 28 March 2009

Redundancy of IL-1 Isoform Signaling and Its Implications for Arterial Remodeling

scientific article

Regulation of matrix metalloproteinases and plasminogen activator inhibitor-1 synthesis by plasminogen in cultured human vascular smooth muscle cells

scientific article published on 01 January 1996

Regulatory T cells in human and angiotensin II-induced mouse abdominal aortic aneurysms

scientific article

Relation of baseline high-sensitivity C-reactive protein level to cardiovascular outcomes with rosuvastatin in the Justification for Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER).

scientific article published on 10 June 2010

Relationship of C-reactive protein reduction to cardiovascular event reduction following treatment with canakinumab: a secondary analysis from the CANTOS randomised controlled trial

scientific article published on 13 November 2017

Relationship of Interleukin-1β Blockade With Incident Gout and Serum Uric Acid Levels: Exploratory Analysis of a Randomized Controlled Trial

scientific article published on 18 September 2018

Relationship of antihypertensive treatment to plasma markers of vascular inflammation and remodeling in the Comparison of Amlodipine versus Enalapril to Limit Occurrences of Thrombosis study ⬇️

scientific article published on April 1, 2012

Relationship of oxidized phospholipids and biomarkers of oxidized low-density lipoprotein with cardiovascular risk factors, inflammatory biomarkers, and effect of statin therapy in patients with acute coronary syndromes: Results from the MIRACL (Myo

scientific article

Reply: The Networks Between the Sympathetic Nervous System and Immune System in Atherosclerosis

scientific article published on 01 July 2016

Report of the National Heart, Lung, and Blood Institute working group on the translation of cardiovascular molecular imaging

scientific article

Report of the National Heart, Lung, and Blood Institute-National Institute of Diabetes and Digestive and Kidney Diseases Working Group on Cardiovascular Complications of Type 1 Diabetes Mellitus

scientific article

Requiem for the 'vulnerable plaque'

scientific article

Residual inflammatory risk associated with interleukin-18 and interleukin-6 after successful interleukin-1β inhibition with canakinumab: further rationale for the development of targeted anti-cytokine therapies for the treatment of atherothrombosis

scientific article published on 01 September 2019

Retinoids Repress Human Cardiovascular Cell Calcification With Evidence for Distinct Selective Retinoid Modulator Effects

scientific article published on 19 December 2019

Role of inflammation in atherosclerosis associated with rheumatoid arthritis

scientific article published on October 2008

Roles of PAD4 and NETosis in Experimental Atherosclerosis and Arterial Injury: Implications for Superficial Erosion

S100A9-RAGE Axis Accelerates Formation of Macrophage-Mediated Extracellular Vesicle Microcalcification in Diabetes Mellitus

scientific article published on 28 May 2020

Safety and efficacy of achieving very low low-density lipoprotein cholesterol levels with rosuvastatin 40 mg daily (from the ASTEROID Study).

scientific article

Seeing and Sampling the Surface of the Atherosclerotic Plaque: Red or White Can Make Blue

scientific article

Selective Inhibition of Matrix Metalloproteinase-13 Increases Collagen Content of Established Mouse Atherosclerosis ⬇️

scientific article published on November 1, 2011

Selective cathepsin S inhibition attenuates atherosclerosis in apolipoprotein E-deficient mice with chronic renal disease

scientific article

Selective matrix metalloproteinase inhibition reduces left ventricular remodeling but does not inhibit angiogenesis after myocardial infarction.

scientific article published in February 2002

Self-reactive CD4+ IL-3+ T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis

scientific article published on 22 January 2019

Self-renewing resident arterial macrophages arise from embryonic CX3CR1(+) precursors and circulating monocytes immediately after birth

scientific article

Sex-related differences of coronary atherosclerosis regression following maximally intensive statin therapy: insights from SATURN.

scientific article published on 17 September 2014

Silencing of CCR2 in myocarditis

scientific article published on 20 June 2014

Sleep modulates haematopoiesis and protects against atherosclerosis

scientific article published on 13 February 2019

Soluble CD40 ligand levels indicate lipid accumulation in carotid atheroma: an in vivo study with high-resolution MRI

scientific article published on 01 January 2003

Soluble CD40L: risk prediction after acute coronary syndromes

scientific article published on 11 August 2003

Sortilin mediates vascular calcification via its recruitment into extracellular vesicles

scientific article

Spatiotemporal controlled delivery of nanoparticles to injured vasculature

scientific article

Stabilization of atherosclerotic plaques: new mechanisms and clinical targets

scientific article

Stage-dependent differential effects of interleukin-1 isoforms on experimental atherosclerosis

scientific article published on 01 August 2019

Statins improve the resolution of established murine venous thrombosis: reductions in thrombus burden and vein wall scarring

scientific article (publication date: 2015)

Statins reduce inflammation in atheroma of nonhuman primates independent of effects on serum cholesterol

scientific article published in September 2002

Stirring the soup of innate immunity in the acute coronary syndromes

scientific article published on 06 May 2010

Superficial erosion and the precision management of acute coronary syndromes: not one-size-fits-all

scientific article

Swell, or Not Too Swell: Cytokines Regulate Arterial Aneurysm Formation

scientific article published in November 2017

Systems Approach to Discovery of Therapeutic Targets for Vein Graft Disease: PPARα Pivotally Regulates Metabolism, Activation, and Heterogeneity of Macrophages and Lesion Development

scientific article published on 06 April 2021

T lymphocytes induce endothelial cell matrix metalloproteinase expression by a CD40L-dependent mechanism: implications for tubule formation

scientific article published on January 1999

T(H)2 predominant immune responses prevail in human abdominal aortic aneurysm

scientific article published on August 2002

T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) mice

scientific article

TLR2 and neutrophils potentiate endothelial stress, apoptosis and detachment: implications for superficial erosion

scientific article published on 8 March 2015

TRAF-1 Deficient Mice Show Impaired Monocyte Recruitment and Decreased Atherogenesis ⬇️

scholarly article

TRAF-1, -2, -3, -5, and -6 are induced in atherosclerotic plaques and differentially mediate proinflammatory functions of CD40L in endothelial cells.

scientific article

Taming Immune and Inflammatory Responses to Treat Atherosclerosis

scientific article published in January 2018

Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction

scientific article

Targeting RNA to lower triglycerides: long strides from short molecules

scientific article published on 01 September 2019

Targeting inflammation in atherosclerosis — from experimental insights to the clinic

scientific article published in 2021

Temporal shifts in clinical presentation and underlying mechanisms of atherosclerotic disease

scientific article

Tension in the Plaque: Hypoxia Modulates Metabolism in Atheroma ⬇️

scientific article published on October 28, 2011

Th2-predominant inflammation and blockade of IFN-gamma signaling induce aneurysms in allografted aortas

scientific article

Th2-predominant inflammation and blockade of IFN-γ signaling induce aneurysms in allografted aortas.

scientific article published in September 2004

The "Intermediate" CD14++CD16+ monocyte subset increases in severe peripheral artery disease in humans

scientific article published on 19 December 2016

The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis

scientific article published on 17 March 2021

The Aging Cardiovascular System: Understanding It at the Cellular and Clinical Levels

scientific article published on April 2017

The American Journal of Cardiology and Journal of Periodontology Editors' Consensus: periodontitis and atherosclerotic cardiovascular disease

scientific article

The American Journal of Cardiology and Journal of Periodontology editors' consensus: periodontitis and atherosclerotic cardiovascular disease

scientific article published in July 2009

The Myocardium: More Than Myocytes

scientific article published on 01 December 2019

The direct effect of injectable cyclosporine and its vehicle, cremophor, on endothelial vascular cell adhesion molecule-1 expression. Ricinoleic acid inhibits coronary artery endothelial activation.

scientific article published on August 1995

The forgotten majority: unfinished business in cardiovascular risk reduction

scientific article

The future of living well to 100.

scientific article

The immune response in atherosclerosis: a double-edged sword

scientific article published on 16 June 2006

The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes

scientific article published on 4 October 2017

The inflammation hypothesis and its potential relevance to statin therapy

scientific article published on 10 January 2007

The ins and outs of inflammatory cells in atheromata

scientific article published on 01 February 2012

The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models

scientific article published on October 2008

The multiple facets of the fat tissue

scientific article published on February 2008

The neutrophil-lymphocyte ratio and incident atherosclerotic events: analyses from five contemporary randomized trials

scientific article published on 08 January 2021

The nuclear factor kappa-B signaling pathway participates in dysregulation of vascular smooth muscle cells in vitro and in human atherosclerosis

scientific article published on June 1997

The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential : A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction

scientific article published on 04 June 2019

The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells

scientific article

The vascular biology of atherosclerosis and imaging targets

scientific article published on 15 April 2010

The vulnerable atherosclerotic plaque: pathogenesis and therapeutic approach

scientific article published on May 2004

The ω-3 fatty acids for Prevention of Post-Operative Atrial Fibrillation trial—rationale and design ⬇️

scientific article published on June 12, 2011

Therapeutic siRNA silencing in inflammatory monocytes in mice

scientific article published on 9 October 2011

Thin-capped atheromata with reduced collagen content in pigs develop in coronary arterial regions exposed to persistently low endothelial shear stress

scientific article

Thoughts on the role of the healing professions and the events of September 11, 2001.

scientific article published in March 2002

Thrombin potently stimulates cytokine production in human vascular smooth muscle cells but not in mononuclear phagocytes.

scientific article published in August 1996

Thrombin promotes activation of matrix metalloproteinase-2 produced by cultured vascular smooth muscle cells

scientific article published on 01 March 1997

Tilting at the tilted protease balance in arterial aneurysmal disease

scientific article published in September 2017

Time-Restricted Salutary Effects of Blood Flow Restoration on Venous Thrombosis and Vein Wall Injury in Mouse and Human Subjects

scientific article published on 15 January 2021

Tissue factor pathway inhibitor-2 is a novel inhibitor of matrix metalloproteinases with implications for atherosclerosis

scientific article

Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge

scientific article published on 12 November 2019

Toll-like receptor 2 mediates apolipoprotein CIII-induced monocyte activation

scientific article

Triglycerides on the rise: should we swap seats on the seesaw?

scientific article published on 29 December 2014

Tumor necrosis factor receptor -1 and -2 double deficiency reduces graft arterial disease in murine cardiac allografts

scientific article published on 01 August 2003

Tumor necrosis factor receptor-associated factor 1 (TRAF1) deficiency attenuates atherosclerosis in mice by impairing monocyte recruitment to the vessel wall

scientific article

Two-dimensional intravascular near-infrared fluorescence molecular imaging of inflammation in atherosclerosis and stent-induced vascular injury

scientific article published on June 2011

Unfriendly Fire From Neutrophils Promiscuously Potentiates Cardiovascular Inflammation

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Vascular biology of atherosclerosis: overview and state of the art.

scientific article

Vascular biomarkers and surrogates in cardiovascular disease

scientific article published in June 2006

Vascular remodeling in transplant vasculopathy

scientific article published on April 2007

Vasospasm of atherosclerotic coronary arteries precipitates acute ischemic myocardial damage in myocardial infarction-prone strain of the Watanabe heritable hyperlipidemic rabbits

scientific article

Vitamin C, collagen, and cracks in the plaque

scientific article published in March 2002

Wild-type but not interferon-gamma-deficient T cells induce graft arterial disease in the absence of B cells

scientific article

c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells

scientific article published on 01 May 2019

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