List of works by Julian Rayner

A Knockout Screen of ApiAP2 Genes Reveals Networks of Interacting Transcriptional Regulators Controlling the Plasmodium Life Cycle

scientific article published on January 2017

A Library of Plasmodium vivax Recombinant Merozoite Proteins Reveals New Vaccine Candidates and Protein-Protein Interactions

scientific article published on 23 December 2015

A Plasmodium calcium-dependent protein kinase controls zygote development and transmission by translationally activating repressed mRNAs

scientific article

A Stem Cell Strategy Identifies Glycophorin C as a Major Erythrocyte Receptor for the Rodent Malaria Parasite Plasmodium berghei.

scientific article

A comprehensive survey of protein palmitoylation in late blood-stage Plasmodium falciparum.

scientific article

A forward genetic screen reveals a primary role for Plasmodium falciparum Reticulocyte Binding Protein Homologue 2a and 2b in determining alternative erythrocyte invasion pathways ⬇️

scientific article published on 29 November 2018

A full-length recombinant Plasmodium falciparum PfRH5 protein induces inhibitory antibodies that are effective across common PfRH5 genetic variants

scientific article published on 10 November 2012

A genome-scale vector resource enables high-throughput reverse genetic screening in a malaria parasite

scientific article

A library of functional recombinant Plasmodium falciparum merozoite surface proteins.

scientific article published on 20 October 2010

A library of functional recombinant cell-surface and secreted P. falciparum merozoite proteins

scientific article

A member of the Plasmodium falciparum PHIST family binds to the erythrocyte cytoskeleton component band 4.1

scientific article (publication date: 11 May 2013)

A novel SNARE complex implicated in vesicle fusion with the endoplasmic reticulum

scientific article

A novel multiple-stage antimalarial agent that inhibits protein synthesis

scientific article (publication date: 18 June 2015)

A plethora of Plasmodium species in wild apes: a source of human infection?

scientific article

A scalable pipeline for highly effective genetic modification of a malaria parasite

scientific article

Adaptation of Plasmodium falciparum to humans involved the loss of an ape-specific erythrocyte invasion ligand ⬇️

scientific article published on 04 October 2019

An Antibody Screen of a Plasmodium vivax Antigen Library Identifies Novel Merozoite Proteins Associated with Clinical Protection

scientific article

An adaptable two-color flow cytometric assay to quantitate the invasion of erythrocytes by Plasmodium falciparum parasites ⬇️

scientific article

An in vitro erythrocyte preference assay reveals that Plasmodium falciparum parasites prefer Type O over Type A erythrocytes.

scientific article published on 25 May 2018

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

scientific article published on 24 February 2021

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

scientific article (publication date: 19 July 2012)

Analysis of protein palmitoylation reveals a pervasive role in Plasmodium development and pathogenesis

scientific article published on August 2012

Antibodies directed against merozoite surface protein-6 are induced by natural exposure to Plasmodium falciparum in a low transmission environment

scientific article

Ape parasite origins of human malaria virulence genes

scientific article

Asymptomatic Plasmodium vivax infections induce robust IgG responses to multiple blood-stage proteins in a low-transmission region of western Thailand

scientific article

Atypical mitogen-activated protein kinase phosphatase implicated in regulating transition from pre-S-Phase asexual intraerythrocytic development of Plasmodium falciparum

scientific article (publication date: September 2013)

Author Correction: Adaptation of Plasmodium falciparum to humans involved the loss of an ape-specific erythrocyte invasion ligand

correction of a scholarly article

Basigin is a druggable target for host-oriented antimalarial interventions

scientific article published on 20 July 2015

Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum ⬇️

scientific article

Binding of Plasmodium falciparum Merozoite Surface Proteins DBLMSP and DBLMSP2 to Human Immunoglobulin M Is Conserved among Broadly Diverged Sequence Variants

scientific article (publication date: July 2016)

Biochemical analysis of the Plasmodium falciparum erythrocyte-binding antigen-175 (EBA175)-glycophorin-A interaction: implications for vaccine design

scientific article (publication date: 8 November 2013)

Biochemical and functional analysis of two Plasmodium falciparum blood-stage 6-cys proteins: P12 and P41

scientific article

CCR4-associated factor 1 coordinates the expression of Plasmodium falciparum egress and invasion proteins ⬇️

scientific article

Calcium Builds Strong Host-Parasite Interactions

scientific article

Confident and sensitive phosphoproteomics using combinations of collision induced dissociation and electron transfer dissociation

scientific article published on 21 March 2014

Conservation and divergence in erythrocyte invasion ligands: Plasmodium reichenowi EBL genes

scientific article

Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis.

scientific article published on 25 May 2016

Cutting edge: the membrane attack complex of complement is required for the development of murine experimental cerebral malaria

scientific article

Defining multiplicity of vector uptake in transfected Plasmodium parasites

scientific article published on 02 July 2020

Dinucleotide repeat polymorphism for HLX1 gene

scientific article published in January 1994

Dramatic difference in diversity between Plasmodium falciparum and Plasmodium vivax reticulocyte binding-like genes.

scientific article

Effects of calcium signaling on Plasmodium falciparum erythrocyte invasion and post-translational modification of gliding-associated protein 45 (PfGAP45) ⬇️

scientific article (publication date: November 2009)

Erythrocyte exit: Out, damned merozoite! Out I say!

scientific article

Evolution of human-chimpanzee differences in malaria susceptibility: relationship to human genetic loss of N-glycolylneuraminic acid

scientific article

Evolution. Great apes and zoonoses

scientific article published on April 2013

Evolutionary history of human revealed by genome-wide analyses of related ape parasites

article published in the Proceedings of the National Academy of Sciences of the United States of America

Extreme mutation bias and high AT content in Plasmodium falciparum

scientific article

Frequent expansion of Plasmodium vivax Duffy Binding Protein in Ethiopia and its epidemiological significance

scientific article published on 7 February 2019

Frequent expansion of Plasmodium vivax Duffy Binding Protein in Ethiopia and its epidemiological significance

scientific article published on 11 September 2019

Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes

scientific article

Generation of antigenic diversity in Plasmodium falciparum by structured rearrangement of Var genes during mitosis

scientific article published on 18 December 2014

Genetic diversity of the malaria vaccine candidate Plasmodium falciparum merozoite surface protein-3 in a hypoendemic transmission environment

scientific article published on March 2009

Genome sequencing of chimpanzee malaria parasites reveals possible pathways of adaptation to human hosts.

scientific article

Genome-Scale Identification of Essential Metabolic Processes for Targeting the Plasmodium Liver Stage

scientific article published on 01 November 2019

Genomes of cryptic chimpanzee Plasmodium species reveal key evolutionary events leading to human malaria.

scientific article

Genomic analysis of local variation and recent evolution in Plasmodium vivax

scientific article

Genomic epidemiology of the current wave of artemisinin resistant malaria

scholarly article by Roberto Amato et al published 22 May 2015 in bioRxiv

Genomic structure, promoter sequence, and revised translation of human homeobox gene HLX1.

scientific article

Getting down to malarial nuts and bolts: the interaction between Plasmodium vivax merozoites and their host erythrocytes

scientific article published in March 2005

Getting stuck in: protein palmitoylation in Plasmodium

scientific article published on 23 September 2012

Global analysis of apicomplexan protein S-acyl transferases reveals an enzyme essential for invasion

scientific article (publication date: August 2013)

High-throughput screens to identify novel interactions between erythrocyte multi-pass receptors and P. falciparum merozoite surface ligands that are involved in invasion.

scientific article

Identification of highly-protective combinations of Plasmodium vivax recombinant proteins for vaccine development

scientific article published on 26 September 2017

Identification of the MNN2 and MNN5 mannosyltransferases required for forming and extending the mannose branches of the outer chain mannans of Saccharomyces cerevisiae.

scientific article

Identifying novel Plasmodium falciparum erythrocyte invasion receptors using systematic extracellular protein interaction screens ⬇️

scientific article published on 13 May 2013

Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum

scientific article published on 16 August 2016

Independent Origin and Global Distribution of Distinct Plasmodium vivax Duffy Binding Protein Gene Duplications

scientific article

Inhibition, tissue distribution and hormonal specificity of a promoter-binding factor for the uteroglobin gene

scientific article published on October 1994

KILchip v1.0: A Novel Merozoite Protein Microarray to Facilitate Malaria Vaccine Candidate Prioritization

scientific article published on 11 December 2018

Landscape of the Plasmodium Interactome Reveals Both Conserved and Species-Specific Functionality.

scientific article published on 6 August 2019

Limited variation in vaccine candidate Plasmodium falciparum Merozoite Surface Protein-6 over multiple transmission seasons

scientific article

Malaria Vaccine Development: Focusing Field Erythrocyte Invasion Studies on Phenotypic Diversity: The West African Merozoite Invasion Network (WAMIN).

scientific article published on 22 December 2015

Malaria Vaccines: Recent Advances and New Horizons

scientific article published on 11 July 2018

Malaria and intestinal helminth co-infection among pregnant women in Ghana: prevalence and risk factors.

scientific article published in June 2009

Malaria immunoepidemiology in low transmission: correlation of infecting genotype and immune response to domains of Plasmodium falciparum merozoite surface protein 3

scientific article

Malaria, intestinal helminths and other risk factors for stillbirth in Ghana

scientific article

Molecular analysis of erythrocyte invasion in Plasmodium falciparum isolates from Senegal ⬇️

scientific article published on 30 April 2007

Multigenomic Delineation of Plasmodium Species of the Laverania Subgenus Infecting Wild-Living Chimpanzees and Gorillas

scientific article

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

scientific article published on 28 April 2013

Neutralization of Plasmodium falciparum merozoites by antibodies against PfRH5.

scientific article

New antigens for a multicomponent blood-stage malaria vaccine

scientific article published in July 2014

Origin of the human malaria parasite Plasmodium falciparum in gorillas

scientific article

Origin of the human malaria parasite Plasmodium falciparum in gorillas.

scientific article

P113 is a merozoite surface protein that binds the N terminus of Plasmodium falciparum RH5

scientific article (publication date: 10 February 2017)

Palmitoyl transferases have critical roles in the development of mosquito and liver stages of Plasmodium

scientific article

Palmitoylation and palmitoyl-transferases in Plasmodium parasites

scientific article published on April 2015

PfSET10, a Plasmodium falciparum methyltransferase, maintains the active var gene in a poised state during parasite division

scientific article (publication date: 19 January 2012)

PhenoPlasm: a database of disruption phenotypes for malaria parasite genes

scientific article

Phenotypic variation of Plasmodium falciparum merozoite proteins directs receptor targeting for invasion of human erythrocytes ⬇️

scientific article (publication date: 3 March 2003)

Phosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca²⁺ signals at key decision points in the life cycle of malaria parasites

scientific article (publication date: March 2014)

PlasmoGEM, a database supporting a community resource for large-scale experimental genetics in malaria parasites

scientific article published on January 2015

Plasmodium falciparum erythrocyte invasion: a conserved myosin associated complex.

scientific article

Plasmodium falciparum erythrocyte invasion: combining function with immune evasion ⬇️

scientific article

Plasmodium falciparum secretory pathway: characterization of PfStx1, a plasma membrane Qa-SNARE

scientific article (publication date: April 2009)

Plasmodium falciparum-like parasites infecting wild apes in southern Cameroon do not represent a recurrent source of human malaria

scientific article

Plasmodium knowlesi as a model system for characterising Plasmodium vivax drug resistance candidate genes.

scientific article published on 03 June 2019

Plasmodium knowlesi genome sequences from clinical isolates reveal extensive genomic dimorphism

scientific article published on April 2015

Plasmodium malariae Malaria: From Monkey to Man?

scientific article published on 7 September 2015

Plasmodium vivax merozoite surface protein PvMSP-3 beta is radically polymorphic through mutation and large insertions and deletions

scientific article published in December 2004

Plasmodium vivax vaccine research - we've only just begun

scientific article

Post-translational protein modifications in malaria parasites

scientific article published on 09 February 2015

Profiling invasive Plasmodium falciparum merozoites using an integrated omics approach ⬇️

scientific article

Proteomic analysis of extracellular vesicles from a Plasmodium falciparum Kenyan clinical isolate defines a core parasite secretome.

scientific article published on 17 July 2017

Quantitation of malaria parasite-erythrocyte cell-cell interactions using optical tweezers

scientific article published on August 2014

Quantitative insertion-site sequencing (QIseq) for high throughput phenotyping of transposon mutants

scientific article

RH5-Basigin interaction plays a major role in the host tropism of Plasmodium falciparum.

scientific article

Rapid evolution of an erythrocyte invasion gene family: the Plasmodium reichenowi Reticulocyte Binding Like (RBL) genes

scientific article published on February 2004

RecQ helicases in the malaria parasite Plasmodium falciparum affect genome stability, gene expression patterns and DNA replication dynamics

article

Recombination-mediated genetic engineering of Plasmodium berghei DNA.

scientific article

Red blood cell tension protects against severe malaria in the Dantu blood group

scientific article published on 16 September 2020

Revealing the sequence and resulting cellular morphology of receptor-ligand interactions during Plasmodium falciparum invasion of erythrocytes ⬇️

scientific article (publication date: February 2015)

Schizont transcriptome variation among clinical isolates and laboratory-adapted clones of the malaria parasite Plasmodium falciparum

scientific article published on 10 December 2018

Semaphorin-7A is an erythrocyte receptor for P. falciparum merozoite-specific TRAP homolog, MTRAP

scientific article (publication date: 2012)

Single cell sequencing shines a light on malaria parasite relatedness in complex infections

scientific article published on 01 February 2020

Single genome amplification and direct amplicon sequencing of Plasmodium spp. DNA from ape fecal specimens

scientific article published on September 2010

Source of the human malaria parasite Plasmodium falciparum

scientific article published on 8 September 2011

Southwestern blotting to establish the composition of UGPB, a putative transcription factor that binds to the rabbit uteroglobin promotor ⬇️

1992 bachelor's thesis by Julian Rayner at Lincoln University

Spatio-temporal dynamics of Plasmodium falciparum transmission within a spatial unit on the Colombian Pacific Coast

scientific article published on 28 February 2020

Study of Plasmodium falciparum DHHC palmitoyl transferases identifies a role for PfDHHC9 in gametocytogenesis

scientific article (publication date: November 2016)

Synergistic malaria vaccine combinations identified by systematic antigen screening

scientific article

The Malaria Cell Atlas: Single parasite transcriptomes across the complete Plasmodium life cycle

scientific article

The Malaria Cell Atlas: a comprehensive reference of single parasite transcriptomes across the complete Plasmodium life cycle: file S1

scientific article published on 22 January 2019

The alveolin IMC1h is required for normal ookinete and sporozoite motility behaviour and host colonisation in Plasmodium berghei

scientific article

The effect of malaria and intestinal helminth coinfection on birth outcomes in Kumasi, Ghana

scientific article

The erythrocyte membrane properties of beta thalassaemia heterozygotes and their consequences for Plasmodium falciparum invasion

scientific article published on 27 May 2022

The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites

scientific article published on 21 July 2017

The merozoite has landed: reticulocyte-binding-like ligands and the specificity of erythrocyte recognition

scientific article published on 23 January 2009

The origins of malaria: there are more things in heaven and earth …

scientific article

The structure of the Plasmodium falciparum EBA175 ligand domain and the molecular basis of host specificity

scientific article published on 23 February 2006

Towards a comprehensive Plasmodium falciparum merozoite cell surface and secreted recombinant protein library

scientific article

Transmembrane domain-dependent sorting of proteins to the ER and plasma membrane in yeast

scientific article published on April 1997

Two Plasmodium falciparum genes express merozoite proteins that are related to Plasmodium vivax and Plasmodium yoelii adhesive proteins involved in host cell selection and invasion ⬇️

scientific article

Ubiquitous Hepatocystis infections, but no evidence of Plasmodium falciparum-like malaria parasites in wild greater spot-nosed monkeys (Cercopithecus nictitans).

scientific article published on 09 June 2012

Uncovering the essential genes of the human malaria parasitePlasmodium falciparumby saturation mutagenesis

scientific article

Using Plasmodium knowlesi as a model for screening Plasmodium vivax blood-stage malaria vaccine targets reveals new candidates

scientific article published on 01 July 2021

Variant merozoite protein expression is associated with erythrocyte invasion phenotypes in Plasmodium falciparum isolates from Tanzania

scientific article

Whole genome sequencing of Plasmodium vivax isolates reveals frequent sequence and structural polymorphisms in erythrocyte binding genes

scientific article published on 12 October 2020

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