List of works by John Danesh

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

scientific article

A cross-platform approach identifies genetic regulators of human metabolism and health

scientific article published on 07 January 2021

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

scientific article published on June 2016

A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease

scientific article published on 13 April 2020

A network of investigator networks in human genome epidemiology

scientific article

A road map for efficient and reliable human genome epidemiology

scientific article published on January 2006

ACE inhibition and cardiometabolic risk factors, lung <i>ACE2</i> and <i>TMPRSS2</i> gene expression, and plasma ACE2 levels: a Mendelian randomization study

scientific article published on 18 November 2020

ACE inhibition and cardiometabolic risk factors, lung ACE2 and TMPRSS2 gene expression, and plasma ACE2 levels: a Mendelian randomization study

scientific article published on 14 April 2020

ANGPTL3 Deficiency and Protection Against Coronary Artery Disease

scientific article published on 29 March 2017

Accuracy of UK Rapid Test Consortium (UK-RTC) "AbC-19 Rapid Test" for detection of previous SARS-CoV-2 infection in key workers: test accuracy study

scientific article published on 11 November 2020

Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19

scientific article

Adiponectin and Coronary Heart Disease

article

Alcohol intake in relation to non-fatal and fatal coronary heart disease and stroke: EPIC-CVD case-cohort study.

scientific article

An Unbiased Lipid Phenotyping Approach To Study the Genetic Determinants of Lipids and Their Association with Coronary Heart Disease Risk Factors

scientific article published on 26 April 2019

Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease.

scientific article published on 24 April 2018

Analysis of protein-coding genetic variation in 60,706 humans

scientific article (publication date: 17 August 2016)

Angiotensin converting enzyme insertion or deletion polymorphism and coronary restenosis: meta-analysis of 16 studies

scientific article published on September 2002

Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease: a mendelian randomisation analysis

scientific article

Apolipoprotein(a) isoforms and the risk of vascular disease: systematic review of 40 studies involving 58,000 participants

scientific article published on May 2010

Are myocardial infarction--associated single-nucleotide polymorphisms associated with ischemic stroke?

scientific article published on 23 February 2012

Assessing the causal association of glycine with risk of cardio-metabolic diseases

scientific article published on 05 March 2019

Association Between Depressive Symptoms and Incident Cardiovascular Diseases

scientific article published on 01 December 2020

Association analyses based on false discovery rate implicate new loci for coronary artery disease ⬇️

scientific article published on 17 July 2017

Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

scientific article (publication date: 15 February 2011)

Association between walking speed and age in healthy, free-living individuals using mobile accelerometry--a cross-sectional study

scientific article

Association of Cardiometabolic Multimorbidity With Mortality

scientific article

Association of Dietary, Circulating, and Supplement Fatty Acids With Coronary Risk

scientific article

Association of Dietary, Circulating, and Supplement Fatty Acids With Coronary Risk

Association of Genetic Variants Related to CETP Inhibitors and Statins With Lipoprotein Levels and Cardiovascular Risk

scientific article

Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular Disease

scientific article published on 02 September 2019

Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis

scientific article published on 01 July 2018

Association of Multiple Biomarkers of Iron Metabolism and Type 2 Diabetes: The EPIC-InterAct Study

scientific article published on 09 February 2016

Association of Plasma Vitamin D Metabolites With Incident Type 2 Diabetes: EPIC-InterAct Case-Cohort Study

Association of Rare and Common Variation in the Lipoprotein Lipase Gene With Coronary Artery Disease

scientific article

Association of Triglyceride-Lowering LPL Variants and LDL-C-Lowering LDLR Variants With Risk of Coronary Heart Disease

scientific article published on 01 January 2019

Association of apolipoprotein E genotypes with lipid levels and coronary risk

scientific article

Association of cholesteryl ester transfer protein genotypes with CETP mass and activity, lipid levels, and coronary risk

scientific article published on June 2008

Association of menopausal characteristics and risk of coronary heart disease: a pan-European case–cohort analysis

scientific article published on 01 August 2019

Association of plasma biomarkers of fruit and vegetable intake with incident type 2 diabetes: EPIC-InterAct case-cohort study in eight European countries

scientific article published on 08 July 2020

Association of the 9p21.3 locus with risk of first-ever myocardial infarction in Pakistanis: case-control study in South Asia and updated meta-analysis of Europeans

scientific article published on 15 April 2010

Associations between differential leucocyte count and incident coronary heart disease: 1764 incident cases from seven prospective studies of 30,374 individuals

scientific article published on 01 August 2004

Author Correction: Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

scientific article published in Nature Communications

Author Correction: Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease

scientific article published in Nature Communications

Author Correction: Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke

scientific article published on 20 February 2020

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

scientific article published on 01 June 2019

Automated typing of red blood cell and platelet antigens: a whole-genome sequencing study

scientific article published on 17 May 2018

B-type natriuretic peptides and cardiovascular risk: systematic review and meta-analysis of 40 prospective studies

scientific article

BRCA2 variants and cardiovascular disease in a multi-ethnic study

scientific article

Big data from electronic health records for early and late translational cardiovascular research: challenges and potential.

scientific article published on 29 August 2017

Body-mass index and all-cause mortality - Authors' reply

scientific article published on 01 June 2017

Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents

scientific article

C-reactive protein and coronary disease: is there a causal link?

scientific article published on 9 November 2009

C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease

scientific article

C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis

scientific article

C-reactive protein concentration and the vascular benefits of statin therapy: an analysis of 20,536 patients in the Heart Protection Study

scientific article

C-reactive protein, fibrinogen, and cardiovascular disease prediction

scientific article published on October 2012

C-reactive protein, fibrinogen, and cardiovascular risk

scientific article published in January 2013

Candidate gene association study of coronary artery calcification in chronic kidney disease: findings from the CRIC study (Chronic Renal Insufficiency Cohort).

scientific article published on 30 May 2013

Cardiovascular Risk Factors Associated With Venous Thromboembolism

Causal Analyses, Statistical Efficiency And Phenotypic Precision Through Recall-By-Genotype Study Design

Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study

scientific article

Chlamydia pneumoniae IgA titres and coronary heart disease: prospective study and meta-analysis

scientific article published in May 2003

Chronic kidney disease and risk of major cardiovascular disease and non-vascular mortality: prospective population based cohort study

scientific article

Circulating concentrations of insulin markers and coronary heart disease: a quantitative review of 19 Western prospective studies

scientific article published on 17 May 2007

Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease.

scientific article

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

scientific article published on 2 March 2016

Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

scientific article published in Nature Communications

Commentary on "A meta-analysis but not a systematic review: an evaluation of the Global BMI Mortality Collaboration".

scientific article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Comparison of four methods to measure haemoglobin concentrations in whole blood donors (COMPARE): A diagnostic accuracy study

scientific article published on 20 December 2020

Consequences Of Natural Perturbations In The Human Plasma Proteome

article

Consumption of Meat, Fish, Dairy Products, and Eggs and Risk of Ischemic Heart Disease

scientific article published on 22 April 2019

Coronary heart disease

Coronary heart disease

scientific article published in 2011

Correction: Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition

scientific article published on 06 March 2020

DNA Sequence Variation in Encoding the Activin-Receptor Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Development and validation of a universal blood donor genotyping platform: a multinational prospective study

scientific article published on 01 August 2020

Diabetes mellitus, fasting glucose, and risk of cause-specific death

scientific article

Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis

scientific article published on 15 June 2020

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

scientific article published on 23 November 2020

Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing.

scientific article published in August 2016

EPIC-Heart: the cardiovascular component of a prospective study of nutritional, lifestyle and biological factors in 520,000 middle-aged participants from 10 European countries

scientific article published on 13 February 2007

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

article by Matthew B. Lanktree et al published June 2012 in American Journal of Human Genetics

Effect of communicating phenotypic and genetic risk of coronary heart disease alongside web-based lifestyle advice: the INFORM Randomised Controlled Trial

scientific article published on 30 March 2019

Efficiency and safety of varying the frequency of whole blood donation (INTERVAL): a randomised trial of 45 000 donors

scientific article published on 20 September 2017

Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study

scientific article

Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies.

scientific article published in February 2019

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 23 January 2018

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

scientific article

Exome-wide association study of plasma lipids in >300,000 individuals

scientific article published on 30 October 2017

Fibrinogen and coronary heart disease: test of causality by 'Mendelian randomization'

scientific article published on 26 July 2006

Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms

scientific article published on 22 May 2017

Five glutathione s-transferase gene variants in 23,452 cases of lung cancer and 30,397 controls: meta-analysis of 130 studies

scientific article

Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference.

scientific article published on 19 February 2018

Four paraoxonase gene polymorphisms in 11212 cases of coronary heart disease and 12786 controls: meta-analysis of 43 studies

scientific article published in February 2004

Fruit and vegetable intake and mortality from ischaemic heart disease: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Heart study

scientific article

Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases

scientific article

GUESS-ing polygenic associations with multiple phenotypes using a GPU-based evolutionary stochastic search algorithm

scientific article

Genetic Risk Score for Coronary Disease Identifies Predispositions to Cardiovascular and Noncardiovascular Diseases

scientific article published on 01 June 2019

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic associations with valvular calcification and aortic stenosis

scientific article published on February 2013

Genetic determinants of major blood lipids in Pakistanis compared with Europeans.

scientific article published on 22 June 2010

Genetic effects on promoter usage are highly context-specific and contribute to complex traits

Genetic effects on promoter usage are highly context-specific and contribute to complex traits

Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genetically determined height and coronary artery disease

scientific article

Genetically modulated educational attainment and coronary disease risk

scientific article published on 01 August 2019

Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program

article

Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke

scientific article published in PLoS ONE

Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2

scientific article

Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length

scientific article published on 27 February 2020

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

scientific article

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

scientific article published on 11 September 2019

Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes

scientific article published on 28 January 2016

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

scientific article

Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India

scientific article

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

scientific article published on 17 January 2018

Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

scientific article

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

scientific article

Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease

scientific article published in Nature Communications

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

scientific article

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention

scientific article published on 01 October 2018

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

scientific article published on 16 October 2020

Genomic atlas of the human plasma proteome

scientific article published in Nature

Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke

scientific article published on 20 December 2019

Glycated hemoglobin measurement and prediction of cardiovascular disease

scientific article

Glycemic index, glycemic load, and risk of coronary heart disease: a pan-European cohort study

scientific article published on 03 July 2020

Haemostatic and inflammatory markers are independently associated with myocardial infarction in men and women

article

Hemostatic and rheological variables and risk of cardiovascular disease

scientific article

Heterozygous ATP-binding Cassette Transporter G5 Gene Deficiency and Risk of Coronary Artery Disease

scientific article published on 30 August 2020

Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias

scientific article (publication date: February 2012)

Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity

scientific article published on April 2017

Human knockouts in a cohort with a high rate of consanguinity

Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

scientific article published on 4 September 2017

Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis

scientific article

Inactivating mutations in NPC1L1 and protection from coronary heart disease

scientific article

Inflammatory cytokines and risk of coronary heart disease: new prospective study and updated meta-analysis

scientific article

Information and Risk Modification Trial (INFORM): design of a randomised controlled trial of communicating different types of information about coronary heart disease risk, alongside lifestyle advice, to achieve change in health-related behaviour

scientific article

Interleukin-6 Receptor Signaling and Abdominal Aortic Aneurysm Growth Rates ⬇️

scientific article published on 01 February 2019

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

scientific article published on 14 March 2012

Interpretation of the evidence for the efficacy and safety of statin therapy

scientific article

Large genome-wide association study identifies three novel risk variants for restless legs syndrome

scientific article published on 25 November 2020

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article

Large-scale evidence that the cardiotoxicity of smoking is not significantly modified by the apolipoprotein E epsilon2/epsilon3/epsilon4 genotype

scientific article published on 01 February 2003

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

scientific article

Leptin and coronary heart disease: prospective study and systematic review

scientific article published on January 2009

Lessons from the INTERVAL study - Authors' reply

scientific article published on 01 June 2018

Lifestyle factors and risk of multimorbidity of cancer and cardiometabolic diseases: a multinational cohort study

scientific article published on 10 January 2020

Lipid-related genes and myocardial infarction in 4685 cases and 3460 controls: discrepancies between genotype, blood lipid concentrations, and coronary disease risk

scientific article published on 15 July 2004

Lipid-related markers and cardiovascular disease prediction

scientific article

Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition

scientific article published on 20 December 2019

Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality

scientific article published on July 2009

Lipoprotein(a) levels and risk of future coronary heart disease: large-scale prospective data

scientific article

Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies

scientific article

Long-term interleukin-6 levels and subsequent risk of coronary heart disease: two new prospective studies and a systematic review

scientific article (publication date: 8 April 2008)

Longer-term efficiency and safety of increasing the frequency of whole blood donation (INTERVAL): extension study of a randomised trial of 20 757 blood donors

scientific article published on 02 August 2019

Major lipids, apolipoproteins, and risk of vascular disease

scientific article published on November 2009

Markers of dysglycaemia and risk of coronary heart disease in people without diabetes: Reykjavik prospective study and systematic review

scientific article

Mendelian Randomization Study of ACLY and Cardiovascular Disease

scientific article published on 01 March 2019

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

scientific article

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

scientific article published on 07 January 2019

Metabolic mediators of body-mass index and cardiovascular risk

scientific article published in The Lancet

Metabolic profiling of angiopoietin-like protein 3 and 4 inhibition: a drug-target Mendelian randomization analysis

scientific article published on 22 December 2020

Metabolomic Consequences of Genetic Inhibition of PCSK9 Compared With Statin Treatment

scientific article published on 27 November 2018

Monitoring indirect impact of COVID-19 pandemic on services for cardiovascular diseases in the UK

scientific article published on 05 October 2020

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 12 March 2018

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

scientific article (publication date: 17 September 2013)

NT-proBNP is associated with coronary heart disease risk in healthy older women but fails to enhance prediction beyond established risk factors: results from the British Women's Heart and Health Study

scientific article published on 13 September 2009

Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis

scientific article

Neutrophil-mediated IL-6 receptor trans-signaling and the risk of chronic obstructive pulmonary disease and asthma

scientific article

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

scientific article published in October 2017

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

scientific article published on 25 February 2019

New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

scholarly article published 12 June 2018

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Parity, breastfeeding and risk of coronary heart disease: A pan-European case-cohort study

scientific article published on 4 July 2016

PhenoScanner V2: an expanded tool for searching human genotype-phenotype associations

scientific article published on 01 November 2019

PhenoScanner: a database of human genotype-phenotype associations.

scientific article published on 17 June 2016

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

scientific article published on 07 September 2020

Phenotypic Characterization of Genetically Lowered Human Lipoprotein(a) Levels

scientific article published on December 2016

Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling

scientific article published on 5 October 2017

Plant foods, dietary fibre and risk of ischaemic heart disease in the European prospective investigation into cancer and nutrition (EPIC) cohort

scientific article published on 27 November 2020

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

scientific article (publication date: 11 August 2012)

Plasma Vitamin C and Type 2 Diabetes: Genome-Wide Association Study and Mendelian Randomization Analysis in European Populations

scientific article published on 17 November 2020

Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis.

scientific article published in October 2005

Platelet function is modified by common sequence variation in megakaryocyte super enhancers

scientific article

Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease.

scientific article

Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease

scientific article published on 15 May 2017

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 01 July 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

scientific article

Rare Protein-Truncating Variants in APOB, Lower Low-Density Lipoprotein Cholesterol, and Protection Against Coronary Heart Disease

scientific article published on 01 May 2019

Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity

scientific article published on 29 June 2017

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders.

scientific article

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

scientific journal article

Recruitment and representativeness of blood donors in the INTERVAL randomised trial assessing varying inter-donation intervals

scientific article published on 20 September 2016

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

scientific article published on 9 April 2018

Regression dilution methods for meta-analysis: assessing long-term variability in plasma fibrinogen among 27,247 adults in 15 prospective studies.

scientific article published on 4 December 2006

Renal function and risk of coronary heart disease in general populations: new prospective study and systematic review

scientific article

Response to Letter Regarding Article, “Adiponectin and Coronary Heart Disease: A Prospective Study and Meta-Analysis”

Risk thresholds for alcohol consumption - Authors' reply

scientific article published on 01 November 2018

Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies.

scientific article

Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies

scientific article

Separate and combined associations of obesity and metabolic health with coronary heart disease: a pan-European case-cohort analysis

scientific article published on 14 August 2017

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 19 December 2017

Serum uric acid and coronary heart disease in 9,458 incident cases and 155,084 controls: prospective study and meta-analysis

scientific article

Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66,155 cases and 91,307 controls.

scientific article

Seven lipoprotein lipase gene polymorphisms, lipid fractions, and coronary disease: a HuGE association review and meta-analysis

scientific article published on 15 October 2008

Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease

scientific article published on 21 February 2020

Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studies

scientific article

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease ⬇️

scientific article published on February 2017

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease

scientific article

The Bangladesh Risk of Acute Vascular Events (BRAVE) Study: objectives and design

scientific article published in May 2015

The Emergence of Networks in Human Genome Epidemiology

article

The INTERVAL trial to determine whether intervals between blood donations can be safely and acceptably decreased to optimise blood supply: study protocol for a randomised controlled trial

scientific article

The Pakistan Risk of Myocardial Infarction Study: a resource for the study of genetic, lifestyle and other determinants of myocardial infarction in South Asia

scientific article published on 30 April 2009

The Polygenic and Monogenic Basis of Blood Traits and Diseases

scientific article published on 01 September 2020

The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: A meta-analysis and Mendelian randomisation analysis

scientific article published on 16 October 2020

The emergence of networks in human genome epidemiology: challenges and opportunities

scholarly article published 18 December 2009

The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The influence of rare variants in circulating metabolic biomarkers

scientific article published on 09 March 2020

The need for risk factor assessment in atherothrombotic vascular disease

scientific article

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

scientific article

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

scientific article published on 12 September 2016

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

scientific article published on 01 September 2020

Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies

scientific article

Triglycerides and the Risk of Coronary Heart Disease

article

Turning the Pump Handle: Evolving Methods for Integrating the Evidence on Gene-Disease Association

article

UK Biobank: Current status and what it means for epidemiology

article

UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age

scientific article published in March 2015

Use of Repeated Blood Pressure and Cholesterol Measurements to Improve Cardiovascular Disease Risk Prediction: An Individual-Participant-Data Meta-Analysis

scientific article

Validation of a Genome-Wide Polygenic Score for Coronary Artery Disease in South Asians

scientific article published on 01 August 2020

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