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List of works by Jakub Fichna

1-Substituted sialorphin analogues-synthesis, molecular modelling and in vitro effect on enkephalins degradation by NEP

scientific article published on 13 July 2019

184 Regulation of the Enteric Neuromotor and Sensory Functions in the Mouse With N-Arachidonoyl-Serotonin (AA-5-HT), a Dual Fatty Acid Amide Hydrolase (FAAH) Inhibitor and TRPV1 Antagonist

scholarly article by Mohammad Bashashati et al published April 2016 in Gastroenterology

A Randomized Clinical Trial of Berberine Hydrochloride in Patients with Diarrhea-Predominant Irritable Bowel Syndrome

scientific article

A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice

scientific article

Abnormal cannabidiol attenuates experimental colitis in mice, promotes wound healing and inhibits neutrophil recruitment

scientific article

Acid loading stimulates rat glomerular mesangial cells proliferation through Na(+)-H (+) exchanger isoform 1 (NHE1)-dependent pathway

scientific article published on 2 April 2013

Activation of the endogenous nociceptin system by selective nociceptin receptor agonist SCH 221510 produces antitransit and antinociceptive effect: a novel strategy for treatment of diarrhea-predominant IBS.

scientific article published on 15 July 2014

AdipoRon, an Orally Active, Synthetic Agonist of AdipoR1 and AdipoR2 Receptors Has Gastroprotective Effect in Experimentally Induced Gastric Ulcers in Mice

scientific article published on 15 May 2021

Alanine scan of sialorphin and its hybrids with opiorphin: synthesis, molecular modelling and effect on enkephalins degradation.

scientific article published on 12 May 2018

Alopecia areata in patients with inflammatory bowel disease: an overview

scientific article

Alterations in the gut barrier and involvement of Toll-like receptor 4 in murine postoperative ileus.

scientific article published on 4 January 2018

Alterations of colonic sensitivity and gastric dysmotility after acute cisplatin and granisetron

scientific article published on 06 November 2018

Anemia of Chronic Disease and Iron Deficiency Anemia in Inflammatory Bowel Diseases: Pathophysiology, Diagnosis, and Treatment

scientific article published on 27 January 2016

Anti-Inflammatory Effect of Homo- and Heterodimers of Natural Enkephalinase Inhibitors in Experimental Colitis in Mice

scientific article published on 10 December 2020

Anti-inflammatory action of a novel orally available peptide 317 in mouse models of inflammatory bowel diseases

scientific article published on 4 April 2014

Anti-inflammatory and antibacterial effects of human cathelicidin active fragment KR-12 in the mouse models of colitis: a novel potential therapy of inflammatory bowel diseases

scientific article published on 21 November 2020

Anti-inflammatory and antinociceptive action of an orally available nociceptin receptor agonist SCH 221510 in a mouse model of inflammatory bowel diseases

scientific article published on 17 December 2013

Anti-inflammatory and antinociceptive action of the dimeric enkephalin peptide biphalin in the mouse model of colitis: new potential treatment of abdominal pain associated with inflammatory bowel diseases

scientific article published on 20 August 2014

Anti-inflammatory effect of dual nociceptin and opioid receptor agonist, BU08070, in experimental colitis in mice

scientific article published on 21 September 2015

Anti-inflammatory effect of novel analogs of natural enkephalinase inhibitors in a mouse model of experimental colitis

scientific article published on 15 November 2016

Anticonvulsant activity of melatonin, but not melatonin receptor agonists Neu-P11 and Neu-P67, in mice.

scientific article

Antidepressant-like effect of endomorphin-1 and endomorphin-2 in mice

scientific article published on 05 July 2006

Antinociceptive and antidepressant-like action of endomorphin-2 analogs with proline surrogates in position 2.

scientific article published on 9 July 2014

Antinociceptive effects of novel melatonin receptor agonists in mouse models of abdominal pain

scientific article published on February 2014

Antinociceptive potency of a fluorinated cyclopeptide Dmt-c[D-Lys-Phe-p-CF3-Phe-Asp]NH2.

scientific article published in December 2018

Antinociceptive potency of enkephalins and enkephalinase inhibitors in the mouse model of colorectal distension-proof-of-concept

scientific article published in March 2018

Beneficial Effects of Probiotics, Prebiotics, Synbiotics, and Psychobiotics in Inflammatory Bowel Disease

scientific article published on July 2015

Berberine Improves Intestinal Motility and Visceral Pain in the Mouse Models Mimicking Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) Symptoms in an Opioid-Receptor Dependent Manner

scientific article

Berberine as a potential therapeutic agent in the treatment of acute pancreatitis

scientific article published on 01 October 2019

Bile acids and FXR in functional gastrointestinal disorders

scientific article published on 30 May 2018

Binding of the new morphiceptin analogs to human MCF-7 breast cancer cells and their effect on growth.

scientific article published on August 2004

Biologic Therapy in Crohn's Disease - What We Learnt so far

scientific article published on 18 December 2019

Biological activity of endomorphin and [Dmt1]endomorphin analogs with six-membered proline surrogates in position 2.

scientific article published on 3 May 2009

Biomarkers for early detection of colitis-associated colorectal cancer - current concepts, future trends

scientific article published on 20 February 2020

Blockade of fructose transporter protein GLUT5 inhibits proliferation of colon cancer cells: proof of concept for a new class of anti-tumor therapeutics

scientific article published in June 2021

Brain-Gut Interactions in IBS

scientific article

Brain-derived neurotrophic factor is elevated in the blood serum of Crohn's disease patients, but is not influenced by anti-TNF-α treatment-A pilot study

scientific article published on 31 August 2020

Cannabinoid Receptor Type 1 and mu-Opioid Receptor Polymorphisms Are Associated With Cyclic Vomiting Syndrome

scientific article

Cannabinoids alleviate experimentally induced intestinal inflammation by acting at central and peripheral receptors

scientific article

Cannabinoids as gastrointestinal anti-inflammatory drugs.

scientific article published on March 2017

Cannabinoids regulate intestinal motor function and electrophysiological activity of myocytes in rodents

scientific article published on 06 August 2015

Chain length of dietary fatty acids determines gastrointestinal motility and visceromotor function in mice in a fatty acid binding protein 4-dependent manner

scientific article published on 27 September 2019

Changes in the diet composition of fatty acids and fiber affect the lower gastrointestinal motility but have no impact on cardiovascular parameters: In vivo and in vitro studies

scientific article published on 30 May 2019

Characteristics of SARS-CoV-2 and potential pharmacological treatment

scientific article published on 09 May 2020

Characterization and distribution of NKD, a receptor for Drosophila tachykinin-related peptide 6.

scientific article

Characterization of antinociceptive activity of novel endomorphin-2 and morphiceptin analogs modified in the third position.

scientific article published in January 2005

Characterization of tachykinin-related peptides from different insect species on Drosophila tachykinin receptor-expressing cell line

scientific article published on November 2006

Characterization of the [125I]endomorphin-2 binding sites in the MCF7 breast cancer cell line.

scientific article

Characterization of the effects of opiorphin and sialorphin and their analogs substituted in position 1 with pyroglutamic acid on motility in the mouse ileum

scientific article published on 4 February 2013

Chemerin in immune response and gastrointestinal pathophysiology

scientific article published on 17 February 2020

Chinese herbal medicines in the treatment of IBD and colorectal cancer: a review

scientific article

Chronic abdominal pain in irritable bowel syndrome - current and future therapies

scientific article published on 09 July 2018

Circadian rhythm abnormalities - Association with the course of inflammatory bowel disease

scientific article published on 28 April 2016

Circadian rhythm abnormalities in patients with inflammatory bowel disease - association with adipokine profile

scientific article published on 17 March 2020

Clinical potential of eluxadoline in the treatment of diarrhea-predominant irritable bowel syndrome

scientific article

Clinical relevance of serum aquaporin-4 antibody levels in neuromyelitis optica

scientific article published on 2 March 2013

Colonic inflammation induces changes in glucose levels through modulation of incretin system

scientific article published in December 2021

Comment on "Intestinal inflammation modulates expression of the iron-regulating hormone hepcidin depending on erythropoietic activity and the commensal microbiota".

scientific article

Comment on Choi et al.: High-fat diet decreases energy expenditure and expression of genes controlling lipid metabolism, mitochondrial function and skeletal system development in the adipose tissue, along with increased expression of extracellular m

scientific article published on 01 August 2015

Common links between metabolic syndrome and inflammatory bowel disease: Current overview and future perspectives

scientific article published on 9 May 2016

Comparison of antagonist activity of spantide family at human neurokinin receptors measured by aequorin luminescence-based functional calcium assay

scientific article published in November 2005

Comparison of the efficacy of available statistical methods for prediction of the hospitalizations number: proof of concept and validation based on the analysis of Polish National Health Fund data in the years 2009-2017

scientific article published on 01 January 2019

Correlations between skin lesions induced by anti-tumor necrosis factor-α and selected cytokines in Crohn's disease patients

scientific article

Corrigendum to "Nrf2 transcriptional activity in the mouse affects the physiological response to tribromoethanol" [Biomed. Pharmacother. 128 (2020) 110317]

scientific article published on 24 November 2020

Corrigendum to "Systemic administration of serotonin exacerbates abdominal pain and colitis via interaction with the endocannabinoid system" [Biochem. Pharmacol. 161 (2019) 37-51]

scientific article published on 14 September 2019

Corrigendum to "The novel peripherally active cannabinoid type 1 and serotonin type 3 receptor agonist AM9405 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome" [Eur. J. Pharmacol. (2018

scientific article published on 10 September 2019

Critical interactions between opioid and cannabinoid receptors during tolerance and physical dependence development to opioids in the murine gastrointestinal tract: proof of concept

scientific article published in August 2021

Cross-talk between serotonin and cannabinoid signaling in the gut, new insights and future perspectives

scientific article published on 7 August 2014

Current overview of extrinsic and intrinsic factors in etiology and progression of inflammatory bowel diseases.

scientific article

Cyclic derivative of morphiceptin Dmt-cyclo-(D-Lys-Phe-D-Pro-Asp)-NH2(P-317), a mixed agonist of MOP and KOP opioid receptors, exerts anti-inflammatory and anti-tumor activity in colitis and colitis-associated colorectal cancer in mice

scientific article published on 21 August 2020

Cyclic derivatives of morphiceptin possess anti-transit effect in the gastrointestinal tract and alleviate abdominal pain in mice

scientific article published on 03 March 2020

Desensitization of transient receptor potential vanilloid type-1 (TRPV1) channel as promising therapy of irritable bowel syndrome: characterization of the action of palvanil in the mouse gastrointestinal tract

scientific article published on 30 January 2020

Design, synthesis and pharmacological characterization of endomorphin analogues with non-cyclic amino acid residues in position 2.

scientific article published on 28 October 2009

Development of the rectal dosage form with silver-coated glass beads for local-action applications in lower sections of the gastrointestinal tract

scientific article published on 31 July 2017

Diagnostic value of chemerin in lower gastrointestinal diseases-a review

scientific article published on 27 August 2018

Dietary fatty acid content influences the expression of genes involved in the lipid turnover and inflammation in mouse colon and spleen

scientific article published on 29 July 2019

Distribution, function and physiological role of melatonin in the lower gut.

scientific article

Dual Functional Capability of Dendritic Cells - Cytokine-Induced Killer Cells in Improving Side Effects of Colorectal Cancer Therapy

scientific article published on 14 March 2017

Effect of 2′,6′-dimethyl-l-tyrosine (Dmt) on pharmacological activity of cyclic endomorphin-2 and morphiceptin analogs

scientific article published on 20 October 2011

Effect of potent endomorphin degradation blockers on analgesic and antidepressant-like responses in mice

scientific article published on 22 July 2011

Effectiveness and therapeutic value of phytochemicals in acute pancreatitis: A review

scientific article published on 03 May 2019

Effects of berberine in the gastrointestinal tract - a review of actions and therapeutic implications

scientific article published on 03 September 2014

Efficacy and safety of serotonin receptor ligands in the treatment of irritable bowel syndrome: a review

scientific article published on 27 December 2017

Elevated risk of venous thromboembolic events in patients with inflammatory myopathies

scientific article

Encenicline, an α7 Nicotinic Acetylcholine Receptor Partial Agonist, Reduces Immune Cell Infiltration in the Colon and Improves Experimental Colitis in Mice

scientific article published on 13 October 2015

Endocannabinoid and cannabinoid-like fatty acid amide levels correlate with pain-related symptoms in patients with IBS-D and IBS-C: a pilot study

scientific article published on 27 December 2013

Endomorphin analogs

scientific article published on January 2007

Endomorphins--endogenous ligands of the mu-opioid receptor

scientific article published in January 2009

Enhancement of anticancer potential of polyphenols by covalent modifications

scientific article

Enkephalin degradation in serum of patients with inflammatory bowel diseases

scientific article published on 02 August 2018

Enkephalinase inhibitors, potential therapeutics for the future treatment of diarrhea predominant functional gastrointestinal disorders

scientific article published on 14 December 2018

Enkephalinases as a new pharmacological target in the treatment of gastrointestinal tract disorders

scientific article published on 02 September 2020

Enzymatic degradation of endomorphins

scientific article published on 31 July 2008

Enzymatic degradation studies of endomorphin-2 and its analogs containing N-methylated amino acids.

scientific article published on 8 August 2005

Estrogen signaling deregulation related with local immune response modulation in irritable bowel syndrome

scientific article published on 31 July 2017

Evaluation of Melatonin Secretion and Metabolism Exponents in Patients with Ulcerative and Lymphocytic Colitis

scientific article published on 29 January 2018

Evaluation of anti-inflammatory effect of silver-coated glass beads in mice with experimentally induced colitis as a new type of treatment in inflammatory bowel disease

scientific article published on 12 January 2017

Experimental colitis in mice is attenuated by topical administration of chlorogenic acid

scientific article published on 7 March 2015

Expression and physiology of opioid receptors in the gastrointestinal tract

scientific article published on February 2016

Expression of FFAR3 and FFAR4 Is Increased in Gastroesophageal Reflux Disease

scientific article published on 20 December 2020

FABP4 blocker attenuates colonic hypomotility and modulates white adipose tissue-derived hormone levels in mouse models mimicking constipation-predominant IBS.

scientific article published on 20 December 2017

Fat-soluble Vitamin Deficiencies and Inflammatory Bowel Disease: Systematic Review and Meta-Analysis

scientific article published on 30 August 2017

Fatty acid amide hydrolase (FAAH) inhibitor PF-3845 reduces viability, migration and invasiveness of human colon adenocarcinoma Colo-205 cell line: an in vitro study

scientific article

Flavanols from Japanese quince (Chaenomeles japonica) fruit suppress expression of cyclooxygenase-2, metalloproteinase-9, and nuclear factor-kappaB in human colon cancer cells

scientific article published on 9 August 2017

Focus on current and future management possibilities in inflammatory bowel disease-related chronic pain

Free Fatty Acid Receptors as new potential target in Colorectal Cancer

scientific article published on 12 November 2019

Free Fatty Acid Receptors as new potential therapeutic target in inflammatory bowel diseases

scientific article published on 14 December 2019

Functional characterization of opioid receptor ligands by aequorin luminescence-based calcium assay

scientific article published on 23 February 2006

Functional comparison of two evolutionary conserved insect neurokinin-like receptors

scientific article published on 4 December 2006

Future Treatment of Constipation-associated Disorders: Role of Relamorelin and Other Ghrelin Receptor Agonists

scientific article published on 23 February 2017

G Protein-Coupled Receptor 30 (GPR30) Expression Pattern in Inflammatory Bowel Disease Patients Suggests its Key Role in the Inflammatory Process. A Preliminary Study

scientific article published on March 2017

G protein-coupled estrogen receptor mediates anti-inflammatory action in Crohn's disease

G protein-coupled receptor 55 (GPR55) expresses differently in patients with Crohn's disease and ulcerative colitis

scientific article published on 8 March 2017

Gastrointestinal Adverse Events of Cannabinoid 1 Receptor Inverse Agonists suggest their Potential Use in Irritable Bowel Syndrome with Constipation: A Systematic Review and Meta-Analysis

scientific article published on 09 December 2019

Genetic factors in pathogenesis, course and treatment of inflammatory bowel diseases

scientific article published on 17 March 2015

Genetic molecular subtypes in optimizing personalized adjuvant therapy in metastatic colorectal cancer

scientific article published on 01 January 2018

Gut microbiota: what is its place in pharmacology?

scientific article published on 29 September 2019

High activity of endogenous opioid system protects against gastric damage development in mouse models of gastric mucosal injury

scientific article published on 25 October 2018

High activity of the endogenous opioid system and acute but not chronic stress influence experimental colitis development in mice

scientific article published on 01 October 2018

IBS-Symptoms in IBD Patients-Manifestation of Concomitant or Different Entities

scientific article published on 24 December 2020

Identification of endomorphin-1 and endomorphin-2 binding sites in human mu-opioid receptor by antisense oligonucleotide strategy

scientific article

In vitro characterization of novel peptide inhibitors of endomorphin-degrading enzymes in the rat brain

scientific article published in September 2006

Inflammation-associated changes in DOR expression and function in the mouse colon

Inflammatory Bowel Disease - From Bench to Bedside

scientific article published on 01 January 2020

Inflammatory bowel disease treatment

scientific article published on 24 May 2016

Inflammatory bowel diseases and reproductive health

scientific article published on 25 March 2016

Inhibition of fatty acid amide hydrolase (FAAH) as a novel therapeutic strategy in the treatment of pain and inflammatory diseases in the gastrointestinal tract

scientific article

Inhibition of ileal bile acid transporter: An emerging therapeutic strategy for chronic idiopathic constipation

scientific article published on June 2015

Inhibition of proteases as a novel therapeutic strategy in the treatment of metabolic, inflammatory and functional diseases of the gastrointestinal tract

scientific article published on 06 April 2013

Inhibition of trigemino-hypoglossal reflex in rats by oxytocin is mediated by mu and kappa opioid receptors

scientific article published in February 2005

Is insulin-like growth factor 1 (IGF-1) system an attractive target inflammatory bowel diseases? Benefits and limitation of potential therapy

scientific article published on 18 March 2016

Ischemic colitis: current diagnosis and treatment

scientific article

Kinetic studies of novel inhibitors of endomorphin degrading enzymes

scientific article

LL-37: Cathelicidin-related antimicrobial peptide with pleiotropic activity

scientific article published on 7 April 2016

Management of pain in colorectal cancer patients

scientific article published on 19 October 2020

Mean Platelet Volume in Crohn's Disease Patients Predicts Sustained Response to a 52-Week Infliximab Therapy: A Pilot Study

scientific article published on 6 October 2015

Melatonin, but not melatonin receptor agonists Neu-P11 and Neu-P67, attenuates TNBS-induced colitis in mice

scientific article published on 22 February 2016

Methyl-orvinol-Dual activity opioid receptor ligand inhibits gastrointestinal transit and alleviates abdominal pain in the mouse models mimicking diarrhea-predominant irritable bowel syndrome

scientific article

Mixed MOP/DOP agonist biphalin elicits anti-transit effect in mouse models mimicking diarrhea-predominant irritable bowel syndrome symptoms

scientific article published on 12 June 2015

Mu-opioid receptor ligands lack receptor subtype selectivity in the aequorin luminescence-based calcium assay

scientific article

Natural and synthetic α-methylenelactones and α-methylenelactams with anticancer potential ⬇️

scientific article published on January 28, 2012

Neuropharmacological characterization of the oneirogenic Mexican plant Calea zacatechichi aqueous extract in mice

scientific article (publication date: June 2016)

New Peptide Inhibitor of Dipeptidyl Peptidase IV, EMDB-1 Extends the Half-Life of GLP-2 and Attenuates Colitis in Mice after Topical Administration

scientific article published on 19 July 2017

New Trends in Liposome-based Drug Delivery in Colorectal Cancer

scientific article published on 01 January 2019

New insights into molecular pathways in colorectal cancer: Adiponectin, interleukin-6 and opioid signaling

scientific article published on 24 October 2020

New neostigmine-based behavioral mouse model of abdominal pain

scientific article published on 01 January 2012

Nociceptin / orphanin FQ (NOP) receptors as novel potential target in the treatment of gastrointestinal diseases

scientific article published on September 2013

Nociceptin effect on intestinal motility depends on opioid-receptor like-1 receptors and nitric oxide synthase co-localization

scientific article published in August 2015

Non-specific abdominal pain and air pollution: a novel association

scientific article (publication date: 2012)

Novel derivatives of 1,2,3-triazole, cannabinoid-1 receptor ligands modulate gastrointestinal motility in mice

scientific article published on 5 February 2018

Novel endomorphin analogues with antagonist activity at the mu-opioid receptor in the gastrointestinal tract

scientific article

Novel glycosylated endomorphin-2 analog produces potent centrally-mediated antinociception in mice after peripheral administration

scientific article published on 30 October 2013

Novel highly potent mu-opioid receptor antagonist based on endomorphin-2 structure

scientific article

Novel investigational drugs for constipation-predominant irritable bowel syndrome: a review

scientific article

Novel mixed NOP/MOP agonist BU08070 alleviates pain and inhibits gastrointestinal motility in mouse models mimicking diarrhea-predominant irritable bowel syndrome symptoms

scientific article published on 6 May 2014

Novel orally available salvinorin A analog PR-38 protects against experimental colitis and reduces abdominal pain in mice by interaction with opioid and cannabinoid receptors

scientific article published on 6 October 2014

Novel selective agonist of GPR18, PSB-KK-1415 exerts potent anti-inflammatory and anti-nociceptive activities in animal models of intestinal inflammation and inflammatory pain

scientific article published on 14 October 2020

Nrf2 transcriptional activity in the mouse affects the physiological response to tribromoethanol

scientific article published on 30 May 2020

One step ahead: miRNA-34 in colon cancer-future diagnostic and therapeutic tool?

scientific article published on 15 September 2018

Opioid antagonist-induced regulation of the mu-opioid receptor expression in MCF-7 breast cancer cell line

scientific article published on January 2009

Opioid peptides in cancer

scientific article published on August 2004

Opioid receptor binding and in vivo antinociceptive activity of position 3-substituted morphiceptin analogs

scientific article

Opioid receptors and their ligands

scientific article

Opioid-induced regulation of mu-opioid receptor gene expression in the MCF-7 breast cancer cell line

scientific article

Opioids in Cancer Development, Progression and Metastasis: Focus on Colorectal Cancer

scientific article published on 22 January 2020

Orally administered novel cyclic pentapeptide P-317 alleviates symptoms of diarrhoea-predominant irritable bowel syndrome

Orally administered novel cyclic pentapeptide P-317 alleviates symptoms of diarrhoea-predominant irritable bowel syndrome

Organometallic Compounds and Metal Complexes in Current and Future Treatments of Inflammatory Bowel Disease and Colorectal Cancer-a Critical Review

scientific article published on 22 August 2019

PhDs in academic gastroenterology: key to a successful career

scientific article published on 27 May 2016

Pharmacological properties of novel cyclic pentapeptides with µ-opioid receptor agonist activity

scientific article

Pharmacology and metabolism of infliximab biosimilars - A new treatment option in inflammatory bowel diseases

scientific article published on 26 April 2016

Physiology, signaling, and pharmacology of opioid receptors and their ligands in the gastrointestinal tract: current concepts and future perspectives

scientific article published on 09 February 2013

Platelet activity in the pathophysiology of inflammatory bowel diseases

scientific article

Polyphenol extract from evening primrose pomace alleviates experimental colitis after intracolonic and oral administration in mice

scientific article published on 31 July 2014

Polyphenols as mitochondria-targeted anticancer drugs

scientific article published on 13 July 2015

Polyunsaturated Fatty Acids and Their Derivatives: Therapeutic Value for Inflammatory, Functional Gastrointestinal Disorders, and Colorectal Cancer

scientific article

Possible application of trefoil factor family peptides in gastroesophageal reflux and Barrett's esophagus

scientific article published on 01 March 2019

Prevention and therapeutic strategies of thromboembolic events in patients with inflammatory bowel diseases: a report of three cases

scientific article

RGS proteins as targets in the treatment of intestinal inflammation and visceral pain: New insights and future perspectives

scientific article published on 28 January 2016

ROLE OF CHEMERIN IN THE PATIENTS WITH INFLAMMATORY BOWEL DISEASES

scientific article published in February 2021

ROLE OF CHEMERIN IN THE PATIENTS WITH INFLAMMATORY BOWEL DISEASES

scientific article published in January 2021

Recent advances in inflammatory bowel disease therapy

scientific article published on 13 September 2020

Recent advances in the pharmacological management of constipation predominant irritable bowel syndrome

scientific article published on 14 November 2019

Response to lubiprostone in chronic constipation is associated with increased mucus and mucin output: a randomized clinical trial

scientific article published on 01 September 2019

Review article: the role of oxidative stress in pathogenesis and treatment of inflammatory bowel diseases

scientific article

Review: The Role of MOP and DOP Receptors in Treatment of Diarrheapredominant Irritable Bowel Syndrome

scientific article

Rhenium-coated glass beads for intracolonic administration attenuate TNBS-induced colitis in mice: Proof-of-Concept Study

scientific article published in January 2015

Role of G protein-coupled orphan receptors in intestinal inflammation: novel targets in inflammatory bowel diseases

scientific article

Role of environmental pollution in irritable bowel syndrome

scientific article

Role of glucagon-like peptides in inflammatory bowel diseases-current knowledge and future perspectives

scientific article published on 29 July 2019

Role of transient receptor potential channels in intestinal inflammation and visceral pain: novel targets in inflammatory bowel diseases

scientific article

Sa1805 BRAIN DERIVED NEUROTROPHIC FACTOR IS ELEVATED IN THE BLOOD SERUM OF CROHN'S DISEASE PATIENTS, BUT DOES NOT CORRELATE WITH THE DISEASE ACTIVITY SCORE

scientific article published in May 2020

Salvinorin A analogues PR-37 and PR-38 attenuate compound 48/80-induced itch responses in mice

scientific article

Salvinorin A and related diterpenes--biological activity and potential therapeutic uses

scientific article published on January 1, 2012

Salvinorin A has antiinflammatory and antinociceptive effects in experimental models of colitis in mice mediated by KOR and CB1 receptors* ⬇️

scientific article published on September 26, 2011

Selective natural kappa opioid and cannabinoid receptor agonists with a potential role in the treatment of gastrointestinal dysfunction

scientific article published on September 2009

Serum Cyclophilin A Correlates with Increased Tissue MMP-9 in Patients with Ulcerative Colitis, but Not with Crohn's Disease

scientific article published on 8 April 2017

Serum Levels of Chemerin in Patients with Inflammatory Bowel Disease as an Indicator of Anti-TNF Treatment Efficacy

scientific article published on 8 October 2021

Sex- and Age-Related Estrogen Signaling Alteration in Inflammatory Bowel Diseases: Modulatory Role of Estrogen Receptors

scientific article published on 28 June 2019

Silver and other metals in the treatment of gastrointestinal diseases

scientific article published on October 2015

Silver nanoparticles based on blackcurrant extract show potent anti-inflammatory effect in vitro and in DSS-induced colitis in mice

scientific article published on 15 June 2020

Single Nucleotide Polymorphisms in Colitis-Associated Colorectal Cancer: a current overview with emphasis on the role of the associated genes products

scientific article published on 26 July 2020

Structure-activity relationship, conformation and pharmacology studies of morphiceptin analogues--selective mu-opioid receptor ligands

scientific article

Supplementation of Bovine Colostrum in Inflammatory Bowel Disease: Benefits and Contraindications

scientific article published on 17 October 2020

Synthesis and antinociceptive activity of cyclic endomorphin-2 and morphiceptin analogs

scientific article published on 10 November 2005

Synthesis and biological activity of N-methylated analogs of endomorphin-2

scientific article published on 06 September 2005

Synthesis and biological activity of endomorphin-2 analogs incorporating piperidine-2-, 3- or 4-carboxylic acids instead of proline in position 2.

scientific article published on 13 June 2008

Synthesis and biological evaluation of cyclic endomorphin-2 analogs

scientific article published on 6 December 2009

Synthesis and biological evaluation of new salvinorin A analogues incorporating natural amino acids

scientific article published on 11 November 2010

Synthesis and biological evaluation of novel peripherally active morphiceptin analogs

scientific article published on 29 April 2010

Synthesis and characterization of potent and selective mu-opioid receptor antagonists, [Dmt(1), D-2-Nal(4)]endomorphin-1 (Antanal-1) and [Dmt(1), D-2-Nal(4)]endomorphin-2 (Antanal-2).

scientific article

Synthesis and evaluation of anti-inflammatory properties of silver nanoparticle suspensions in experimental colitis in mice

scientific article published on 02 November 2016

Synthesis and opioid activity of novel 6-ketolevorphanol derivatives

scientific article published on February 2013

Synthesis and opioid activity of novel 6-substituted-6-demethoxy-ethenomorphinans

scientific article published on 29 March 2010

Synthesis of target-specific radiolabeled peptides for diagnostic imaging

scientific article

Systemic administration of serotonin exacerbates abdominal pain and colitis via interaction with the endocannabinoid system

scientific article published on 03 January 2019

THE EVALUATION OF SERUM SEROTONIN LEVEL AMONG PATIENTS WITH CROHN’S DISEASE AND ITS IMPACT ON QUALITY OF LIFE

scientific article published in January 2021

THE EVALUATION OF SERUM SEROTONIN LEVEL AMONG PATIENTS WITH CROHN’S DISEASE AND ITS IMPACT ON QUALITY OF LIFE

scientific article published in February 2021

Targeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal

scientific article

Targeting fatty acid amide hydrolase and transient receptor potential vanilloid-1 simultaneously to modulate colonic motility and visceral sensation in the mouse: A pharmacological intervention with N-arachidonoyl-serotonin (AA-5-HT).

scientific article

Tenapanor hydrochloride for the treatment of constipation-predominant irritable bowel syndrome

scientific article published on 12 June 2015

The Anti-Inflammatory Effect and Intestinal Barrier Protection of HU210 Differentially Depend on TLR4 Signaling in Dextran Sulfate Sodium-Induced Murine Colitis

scientific article

The Involvement of the Endogenous Opioid System in the Gastrointestinal Aging in Mice and Humans

scientific article published on 24 March 2022

The Nrf2 in the pathophysiology of the intestine: molecular mechanisms and therapeutic implications for inflammatory bowel diseases

scientific article published on 17 October 2020

The endomorphin system and its evolving neurophysiological role

scientific article published on March 2007

The influence of family pattern abnormalities in the early stages of life on the course of inflammatory bowel diseases

scientific article

The influence of lipoic acid on caveolin-1-regulated antioxidative enzymes in the mouse model of acute ulcerative colitis

scientific article published on 26 September 2016

The influence of opioids on urokinase plasminogen activator on protein and mRNA level in MCF-7 breast cancer cell line

scientific article

The link between cardiovascular and circulatory events in inflammatory gastrointestinal disorders

scientific article published on 01 January 2015

The mechanisms linking obesity to colon cancer: An overview

scientific article published on 7 February 2018

The mu-opioid receptor-selective peptide antagonists, antanal-1 and antanal-2, produce anticonvulsant effects in mice

scientific article published on 11 August 2012

The novel endomorphin degradation blockers Tyr-Pro-DClPhe-Phe-NH (EMDB-1) and Tyr-Pro-Ala-NH (EMDB-2) prolong endomorphin-2 action in rat ileum in vitro

scientific article published on 23 April 2010

The novel peripherally active cannabinoid type 1 and serotonin type 3 receptor agonist AM9405 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome

scientific article published on 17 August 2018

The past, present and future of gastroenterology in Europe and worldwide

scientific article published on April 2015

The place of sphingosine-1-phosphate modulators in the therapy of inflammatory bowel diseases

scientific article published on 09 March 2020

The place of tachykinin NK2 receptor antagonists in the treatment diarrhea-predominant irritable bowel syndrome

scientific article published on 01 February 2019

The role of AST-120 and protein-bound uremic toxins in irritable bowel syndrome: a therapeutic perspective

scientific article (publication date: September 2015)

The role of adipose tissue in the pathogenesis of Crohn's disease

scientific article published on 28 September 2018

The role of morphine in regulation of cancer cell growth

scientific article published on 29 July 2011

Traditional Chinese Medicine Da-Cheng-Qi-Tang Ameliorates Impaired Gastrointestinal Motility and Intestinal Inflammatory Response in a Mouse Model of Postoperative Ileus

scientific article published on 31 July 2020

Transient receptor potential vanilloid 4 inhibits mouse colonic motility by activating NO-dependent enteric neurotransmission

scientific article

Triphala: current applications and new perspectives on the treatment of functional gastrointestinal disorders.

scientific article

Visualization of Estrogen Receptors in Colons of Mice with TNBS-Induced Crohn's Disease using Immunofluorescence

scientific article published on 12 March 2020

Walnut Oil Alleviates Intestinal Inflammation and Restores Intestinal Barrier Function in Mice

scientific article published on 02 May 2020

What is the Future of the Gut Microbiota-Related Treatment? Toward Modulation of Microbiota in Preventive and Therapeutic Medicine

scientific article published on 10 July 2014

What role do cannabinoids have in modern medicine as gastrointestinal anti-inflammatory drugs?

scientific article published on 31 July 2020

Young GI angle: My biggest (career) mistake

Young GI angle: The role of bibliometrics in scientist's career development

scientific article published in December 2017

Young Talent Group launches actions for young gastroenterologists by introducing the UEG Young GI Network

scientific article

[(35)S]GTPgammaS binding stimulated by endomorphin-2 and morphiceptin analogs

scientific article published on 27 April 2006

[D-1-Nal4]endomorphin-2 is a potent micro-opioid receptor antagonist in the aequorin luminescence-based calcium assay

scientific article published on 21 March 2006

[Dmt1, d-1-Nal3]morphiceptin, a novel opioid peptide analog with high analgesic activity

scientific article

[Opioid receptors and their selective ligands]

scientific article published on 01 January 2006

[Strategies in Crohn's disease treatment - "step-up" vs. "top-down"]

scientific article published on 04 January 2020

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