List of works - Julie McElrath

Immune-correlates analysis of an HIV-1 vaccine efficacy trial

scientific article (publication date: 5 April 2012)

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

scientific article (publication date: 13 November 2008)

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

scientific article

HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis

scientific article

Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2.

scientific article

Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine

scientific article

Initial events in establishing vaginal entry and infection by human immunodeficiency virus type-1.

scientific article published in February 2007

Setting the stage: host invasion by HIV.

scientific article published on June 2008

Immunization with envelope subunit vaccine products elicits neutralizing antibodies against laboratory-adapted but not primary isolates of human immunodeficiency virus type 1. The National Institute of Allergy and Infectious Diseases AIDS Vaccine Ev

scientific article published in February 1996

MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data

scientific article

Cytotoxic-T-Cell Responses, Viral Load, and Disease Progression in Early Human Immunodeficiency Virus Type 1 Infection

scientific article published on October 30, 1997

Safety and efficacy of the HVTN 503/Phambili study of a clade-B-based HIV-1 vaccine in South Africa: a double-blind, randomised, placebo-controlled test-of-concept phase 2b study

scientific article

Induction of immunity to human immunodeficiency virus type-1 by vaccination

scientific article

HIV-1 integration landscape during latent and active infection

scientific article

Optimization and validation of an 8-color intracellular cytokine staining (ICS) assay to quantify antigen-specific T cells induced by vaccination

scientific article published on 3 April 2007

Genetic impact of vaccination on breakthrough HIV-1 sequences from the STEP trial

scientific article published on February 27, 2011

Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology

scientific article

Variable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) response

scientific article published in April 2009

HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1.

scientific article

Defining blood processing parameters for optimal detection of cryopreserved antigen-specific responses for HIV vaccine trials

scientific article published on 28 February 2007

Clade B-based HIV-1 vaccines elicit cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers

scientific article

Protective HIV-specific CD8+ T cells evade Treg cell suppression

scientific article published on July 17, 2011

Mononuclear phagocytes of blood and bone marrow: comparative roles as viral reservoirs in human immunodeficiency virus type 1 infections

scientific article

Safety and Immunogenicity of Novel Adenovirus Type 26- and Modified Vaccinia Ankara-Vectored Ebola Vaccines: A Randomized Clinical Trial

scientific article

COMPASS identifies T-cell subsets correlated with clinical outcomes

scientific article

A framework for assessing immunological correlates of protection in vaccine trials

scientific article published on 2 October 2007

A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204)

scientific article (publication date: 2011)

HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies

scientific article published on 30 July 2015

Immune responses to human immunodeficiency virus (HIV) type 1 induced by canarypox expressing HIV-1MN gp120, HIV-1SF2 recombinant gp120, or both vaccines in seronegative adults. NIAID AIDS Vaccine Evaluation Group

scientific article published in May 1998

Comprehensive analysis of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon-secreting CD8+ T cells in primary HIV-1 infection

scientific article

CXCL13 is a plasma biomarker of germinal center activity

scientific article published on 23 February 2016

Selection on the human immunodeficiency virus type 1 proteome following primary infection

scientific article

A canarypox vaccine expressing multiple human immunodeficiency virus type 1 genes given alone or with rgp120 elicits broad and durable CD8+ cytotoxic T lymphocyte responses in seronegative volunteers

scientific article published in August 1999

Merck Ad5/HIV induces broad innate immune activation that predicts CD8⁺ T-cell responses but is attenuated by preexisting Ad5 immunity

scientific article

Peptide selection for human immunodeficiency virus type 1 CTL-based vaccine evaluation

scientific article published on 27 June 2006

Human adenovirus-specific T cells modulate HIV-specific T cell responses to an Ad5-vectored HIV-1 vaccine

scientific article published on 27 December 2011

Evolution of CD8+ T cell immunity and viral escape following acute HIV-1 infection

scientific article

QS-21 promotes an adjuvant effect allowing for reduced antigen dose during HIV-1 envelope subunit immmunization in humans

article

Divergent patterns of progression to AIDS after infection from the same source: human immunodeficiency virus type 1 evolution and antiviral responses

scientific article published in June 1997

Human immunodeficiency virus type 1 mediates global disruption of innate antiviral signaling and immune defenses within infected cells

scientific article published on 12 August 2009

Enhanced immunity to human immunodeficiency virus (HIV) envelope elicited by a combined vaccine regimen consisting of priming with a vaccinia recombinant expressing HIV envelope and boosting with gp160 protein

scientific article

Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trial

scientific article published on February 2007

HIV-1 induces cytotoxic T lymphocytes in the cervix of infected women

scientific article

Origin and differentiation of human memory CD8 T cells after vaccination

scientific article published on 13 December 2017

Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multi-protein recombinant vaccine in uninfected human volunteers

scientific article published on 10 August 2006

Effect of combination antiretroviral therapy on T-cell immunity in acute human immunodeficiency virus type 1 infection

scientific article published in January 2000

Preservation of T Cell Proliferation Restricted by Protective HLA Alleles Is Critical for Immune Control of HIV-1 Infection

article

Role for HLA class II molecules in HIV-1 suppression and cellular immunity following antiretroviral treatment

scientific article

FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial

scientific article

Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposure

scientific article

List of works by Julie McElrath

Immune-correlates analysis of an HIV-1 vaccine efficacy trial

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis

Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2.

Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine

Initial events in establishing vaginal entry and infection by human immunodeficiency virus type-1.

Setting the stage: host invasion by HIV.

Immunization with envelope subunit vaccine products elicits neutralizing antibodies against laboratory-adapted but not primary isolates of human immunodeficiency virus type 1. The National Institute of Allergy and Infectious Diseases AIDS Vaccine Ev

MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data

Cytotoxic-T-Cell Responses, Viral Load, and Disease Progression in Early Human Immunodeficiency Virus Type 1 Infection

Safety and efficacy of the HVTN 503/Phambili study of a clade-B-based HIV-1 vaccine in South Africa: a double-blind, randomised, placebo-controlled test-of-concept phase 2b study

Induction of immunity to human immunodeficiency virus type-1 by vaccination

HIV-1 integration landscape during latent and active infection

Optimization and validation of an 8-color intracellular cytokine staining (ICS) assay to quantify antigen-specific T cells induced by vaccination

Genetic impact of vaccination on breakthrough HIV-1 sequences from the STEP trial

Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology

Variable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) response

HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1.

Defining blood processing parameters for optimal detection of cryopreserved antigen-specific responses for HIV vaccine trials

Clade B-based HIV-1 vaccines elicit cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers

Protective HIV-specific CD8+ T cells evade Treg cell suppression

Mononuclear phagocytes of blood and bone marrow: comparative roles as viral reservoirs in human immunodeficiency virus type 1 infections

Safety and Immunogenicity of Novel Adenovirus Type 26- and Modified Vaccinia Ankara-Vectored Ebola Vaccines: A Randomized Clinical Trial

COMPASS identifies T-cell subsets correlated with clinical outcomes

A framework for assessing immunological correlates of protection in vaccine trials

A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204)

HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies

Immune responses to human immunodeficiency virus (HIV) type 1 induced by canarypox expressing HIV-1MN gp120, HIV-1SF2 recombinant gp120, or both vaccines in seronegative adults. NIAID AIDS Vaccine Evaluation Group

Comprehensive analysis of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon-secreting CD8+ T cells in primary HIV-1 infection

CXCL13 is a plasma biomarker of germinal center activity

Selection on the human immunodeficiency virus type 1 proteome following primary infection

A canarypox vaccine expressing multiple human immunodeficiency virus type 1 genes given alone or with rgp120 elicits broad and durable CD8+ cytotoxic T lymphocyte responses in seronegative volunteers

Merck Ad5/HIV induces broad innate immune activation that predicts CD8⁺ T-cell responses but is attenuated by preexisting Ad5 immunity

Peptide selection for human immunodeficiency virus type 1 CTL-based vaccine evaluation

Human adenovirus-specific T cells modulate HIV-specific T cell responses to an Ad5-vectored HIV-1 vaccine

Evolution of CD8+ T cell immunity and viral escape following acute HIV-1 infection

QS-21 promotes an adjuvant effect allowing for reduced antigen dose during HIV-1 envelope subunit immmunization in humans

Divergent patterns of progression to AIDS after infection from the same source: human immunodeficiency virus type 1 evolution and antiviral responses

Human immunodeficiency virus type 1 mediates global disruption of innate antiviral signaling and immune defenses within infected cells

Enhanced immunity to human immunodeficiency virus (HIV) envelope elicited by a combined vaccine regimen consisting of priming with a vaccinia recombinant expressing HIV envelope and boosting with gp160 protein

Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trial

HIV-1 induces cytotoxic T lymphocytes in the cervix of infected women

Origin and differentiation of human memory CD8 T cells after vaccination

Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multi-protein recombinant vaccine in uninfected human volunteers

Effect of combination antiretroviral therapy on T-cell immunity in acute human immunodeficiency virus type 1 infection

Preservation of T Cell Proliferation Restricted by Protective HLA Alleles Is Critical for Immune Control of HIV-1 Infection

Role for HLA class II molecules in HIV-1 suppression and cellular immunity following antiretroviral treatment

FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial

Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposure