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List of works by Éric A. Cohen

A late role for the association of hnRNP A2 with the HIV-1 hnRNP A2 response elements in genomic RNA, Gag, and Vpr localization

scientific article

Activation of the ILT7 receptor and plasmacytoid dendritic cell responses are governed by structurally-distinct BST2 determinants

scientific article published on 22 May 2019

Analysis of HIV-1 Vpr determinants responsible for cell growth arrest in Saccharomyces cerevisiae

scientific article

Antagonism of tetherin restriction of HIV-1 release by Vpu involves binding and sequestration of the restriction factor in a perinuclear compartment

scientific article

Assessing the Innate Sensing of HIV-1 Infected CD4+ T Cells by Plasmacytoid Dendritic Cells Using an Ex vivo Co-culture System

scientific article published on September 2015

Assessment of the role of the central DNA flap in human immunodeficiency virus type 1 replication by using a single-cycle replication system

scientific article published on March 2004

Association between disruption of CD4 receptor dimerization and increased human immunodeficiency virus type 1 entry

scientific article published on 8 June 2006

Attacking the Supply Lines: HIV-1 Restricts Alanine Uptake to Prevent T Cell Activation

scientific article

CD4 dimers constitute the functional component required for T cell activation

scientific article

CD4/CXCR4 co-expression allows productive HIV-1 infection in canine kidney MDCK cells

scientific article

Cell context-dependent involvement of ATR in early stages of retroviral replication

scientific article

Cell-surface processing of extracellular human immunodeficiency virus type 1 Vpr by proprotein convertases

scientific article published on 03 December 2007

Comparison of human immunodeficiency virus (HIV)-specific infection-enhancing and -inhibiting antibodies in AIDS patients

scientific article

Conserved residues within the HIV-1 Vpu transmembrane-proximal hinge region modulate BST2 binding and antagonism.

scientific article

Contribution of the C-terminal region within the catalytic core domain of HIV-1 integrase to yeast lethality, chromatin binding and viral replication

scientific article

Contribution of the C-terminal tri-lysine regions of human immunodeficiency virus type 1 integrase for efficient reverse transcription and viral DNA nuclear import

scientific article

Defining the interactions and role of DCAF1/VPRBP in the DDB1-cullin4A E3 ubiquitin ligase complex engaged by HIV-1 Vpr to induce a G2 cell cycle arrest

scientific article

Deregulation of microRNAs by HIV-1 Vpr leads to the development of neurocognitive disorders.

scientific article published on 3 October 2011

Deregulation of microRNAs by HIV-1 Vpr protein leads to the development of neurocognitive disorders

erratum published in 2013

Deregulation of microRNAs by HIV-1 Vpr protein leads to the development of neurocognitive disorders

erratum published in September 2013

Deregulation of microRNAs by HIV-1 Vpr protein leads to the development of neurocognitive disorders.

scientific article

Design of a trans protease lentiviral packaging system that produces high titer virus

scientific article published on 28 December 2007

Differential Control of BST2 Restriction and Plasmacytoid Dendritic Cell Antiviral Response by Antagonists Encoded by HIV-1 Group M and O Strains

scientific article

Differential type 1 interferon-regulated gene expression in the brain during AIDS: interactions with viral diversity and neurovirulence

scientific article published on 22 April 2013

Distinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity

Dual mechanisms of translation initiation of the full-length HIV-1 mRNA contribute to gag synthesis

scientific article

Effect of calcium-modulating cyclophilin ligand on human immunodeficiency virus type 1 particle release and cell surface expression of tetherin

scientific article published on 30 September 2009

Efficient BST2 antagonism by Vpu is critical for early HIV-1 dissemination in humanized mice

scientific article published on 6 November 2013

Enhancing Virion Tethering by BST2 Sensitizes Productively and Latently HIV-infected T cells to ADCC Mediated by Broadly Neutralizing Antibodies.

scientific article

Expression of MDM2 in Macrophages Promotes the Early Postentry Steps of HIV-1 Infection through Inhibition of p53

scientific article published on 21 March 2019

Extracellular human immunodeficiency virus type 1 viral protein R causes reductions in astrocytic ATP and glutathione levels compromising the antioxidant reservoir

scientific article published on June 9, 2012

Flt3L-Mediated Expansion of Plasmacytoid Dendritic Cells Suppresses HIV Infection in Humanized Mice

scientific article published on 01 November 2019

Formation of mobile chromatin-associated nuclear foci containing HIV-1 Vpr and VPRBP is critical for the induction of G2 cell cycle arrest

scientific article

From arrest to escape: HIV-1 Vpr cuts a deal

scientific article

Functional analysis of the phosphorylation sites on the human immunodeficiency virus type 1 Vpu protein

scientific article

Genetic selection of peptide inhibitors of human immunodeficiency virus type 1 Vpr.

scientific article

HIV Nef and Vpu protect HIV-infected CD4+ T cells from antibody-mediated cell lysis through down-modulation of CD4 and BST2.

scientific article

HIV infection and persistence in pulmonary mucosal double negative T-cells in vivo

scientific article published on 23 September 2020

HIV persists in CCR6+CD4+ T cells from colon and blood during antiretroviral therapy

scientific article

HIV-1 Viral Protein R Activates NLRP3 Inflammasome in Microglia: implications for HIV-1 Associated Neuroinflammation

scientific article published on 10 October 2016

HIV-1 Vpr causes neuronal apoptosis and in vivo neurodegeneration.

scientific article published on April 2007

HIV-1 Vpr hijacks EDD-DYRK2-DDB1DCAF1 to disrupt centrosome homeostasis.

scientific article

HIV-1 Vpr induces the K48-linked polyubiquitination and proteasomal degradation of target cellular proteins to activate ATR and promote G2 arrest

scientific article published on 20 January 2010

HIV-1 Vpr up-regulates expression of ligands for the activating NKG2D receptor and promotes NK cell-mediated killing

scientific article

HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase

scientific article

HIV-1 Vpu Disarms Natural Killer Cells

scientific article published on November 18, 2010

HIV-1 Vpu Downmodulates ICAM-1 Expression, Resulting in Decreased Killing of Infected CD4+ T Cells by NK Cells

scientific article published on February 2017

HIV-1 is rarely detected in blood and colon myeloid cells during viral-suppressive antiretroviral therapy

scientific article published on 01 July 2019

HIV-1 viral protein R causes peripheral nervous system injury associated with in vivo neuropathic pain

scientific article published on 13 July 2010

HIV-induced neuroinflammation: impact of PAR1 and PAR2 processing by Furin

article

HIV‐1 Vpu Antagonizes BST‐2 by Interfering Mainly with the Trafficking of Newly Synthesized BST‐2 to the Cell Surface

scientific article published on October 3, 2011

Hepatitis C virus core protein induces neuroimmune activation and potentiates Human Immunodeficiency Virus-1 neurotoxicity

scientific article

Host MicroRNAs-221 and -222 Inhibit HIV-1 Entry in Macrophages by Targeting the CD4 Viral Receptor

scientific article published on October 2017

Human immunodeficiency virus type 1 Vpr-mediated G(2) cell cycle arrest: Vpr interferes with cell cycle signaling cascades by interacting with the B subunit of serine/threonine protein phosphatase 2A

scientific article

Hypophosphorylation of poly(A) polymerase and increased polyadenylation activity are associated with human immunodeficiency virus type 1 Vpr expression

scientific article

Implications of Spike-glycoprotein processing at S1/S2 by Furin, at S2’ by Furin and/or TMPRSS2 and shedding of ACE2: cell-to-cell fusion, cell entry and infectivity of SARS-CoV-2

retracted scholarly article by Rachid Essalmani published in July 2021

Implications of Spike-glycoprotein processing at S1/S2 by Furin, at S2’ by Furin and/or TMPRSS2 and shedding of ACE2: cell-to-cell fusion, cell entry and infectivity of SARS-CoV-2

scientific article

Importin alpha3 interacts with HIV-1 integrase and contributes to HIV-1 nuclear import and replication

scientific article

Incorporation of Ebola glycoprotein into HIV particles facilitates dendritic cell and macrophage targeting and enhances HIV-specific immune responses

article

Inflammation and epithelial cell injury in AIDS enteropathy: involvement of endoplasmic reticulum stress

scientific article

Insulin Treatment Prevents Neuroinflammation and Neuronal Injury with Restored Neurobehavioral Function in Models of HIV/AIDS Neurodegeneration.

scientific article published on October 2016

Interactions between human immunodeficiency virus (HIV)-1 Vpr expression and innate immunity influence neurovirulence

scientific article published on 6 June 2011

Interleukin-1β Triggers p53-Mediated Downmodulation of CCR5 and HIV-1 Entry in Macrophages through MicroRNAs 103 and 107

scientific article published on 29 September 2020

International AIDS Society global scientific strategy: towards an HIV cure 2016.

scientific article published on 11 July 2016

Jean-Luc Darlix: Renaissance scientist and retrovirologist par excellence

scientific article published on July 18, 2011

L-Carnitine Tartrate Downregulates the ACE2 Receptor and Limits SARS-CoV-2 Infection

scientific article

Lentivirus Vpr and Vpx accessory proteins usurp the cullin4–DDB1 (DCAF1) E3 ubiquitin ligase

scientific article published on October 10, 2012

Major histocompatibility complex class II molecules promote human immunodeficiency virus type 1 assembly and budding to late endosomal/multivesicular body compartments.

scientific article published on October 2006

Major histocompatibility complex class-II molecules promote targeting of human immunodeficiency virus type 1 virions in late endosomes by enhancing internalization of nascent particles from the plasma membrane

scientific article

MicroRNA profiling reveals new aspects of HIV neurodegeneration: caspase-6 regulates astrocyte survival

scientific article published on 22 January 2010

Modulation of HIV-1-host interaction: role of the Vpu accessory protein

scientific article published on December 22, 2010

Modulation of NKG2D-mediated cytotoxic functions of natural killer cells by viral protein R from HIV-1 primary isolates.

scientific article

Modulation of allergic airway inflammation by the oral pathogen Porphyromonas gingivalis

scientific article

Naturally-Occurring Genetic Variants in Human DC-SIGN Increase HIV-1 Capture, Cell-Transfer and Risk of Mother-To-Child Transmission

scientific article published on July 10, 2012

Neuroinflammation-Induced Interactions between Protease-Activated Receptor 1 and Proprotein Convertases in HIV-Associated Neurocognitive Disorder

scientific article

New pandemics: HIV and AIDS, HCV and chronic hepatitis, influenza virus and flu

scientific article

Ombitasvir/paritaprevir/ritonavir and dasabuvir with or without sofosbuvir for patients with hepatitis C virus genotype 1 infection who failed a prior course of direct-acting antiviral therapy

scientific article published on 19 March 2019

Oral pathogens and allergic disease: results from the Third National Health and Nutrition Examination Survey.

scientific article

Pharmacological Inhibition of PPARy Boosts HIV Reactivation and Th17 Effector Functions, While Preventing Progeny Virion Release and de novo Infection

scientific article published on 30 September 2020

Productive human immunodeficiency virus type 1 assembly takes place at the plasma membrane.

scientific article published on 16 May 2007

Recent advances in the understanding of HIV-1 Vpu accessory protein functions

scientific article

Reduced antiretroviral drug efficacy and concentration in HIV-infected microglia contributes to viral persistence in brain

scientific article published on 16 October 2017

Regulation of CD4 Receptor and HIV-1 Entry by MicroRNAs-221 and -222 during Differentiation of THP-1 Cells.

scientific article published on 30 December 2017

Remodeling of the Host Cell Plasma Membrane by HIV-1 Nef and Vpu: A Strategy to Ensure Viral Fitness and Persistence

scientific article

Requirements for the selective degradation of CD4 receptor molecules by the human immunodeficiency virus type 1 Vpu protein in the endoplasmic reticulum.

scientific article

Role of CD4 receptor down-regulation during HIV-1 infection

scientific article published on January 2004

Role of envelope processing and gp41 membrane spanning domain in the formation of human immunodeficiency virus type 1 (HIV-1) fusion-competent envelope glycoprotein complex

scientific article published on 28 November 2006

Safety of the 2D/3D direct-acting antiviral regimen in HCV-induced Child-Pugh A cirrhosis - A pooled analysis

scientific article

Suppression of Tetherin-restricting activity upon human immunodeficiency virus type 1 particle release correlates with localization of Vpu in the trans-Golgi network

scientific article published on 25 February 2009

The HIV-1 Accessory Protein Vpu Downregulates Peroxisome Biogenesis

scientific article published on 03 March 2020

The evaluation of risk-benefit ratio for gut tissue sampling in HIV cure research

scientific article published in October 2017

The human immunodeficiency virus type 1 Vpr protein upregulates PVR via activation of the ATR-mediated DNA damage response pathway

scientific article

The tyrosine-based YXXØ targeting motif of murine leukemia virus envelope glycoprotein affects pathogenesis

scientific article published on June 2004

Two-step purification of His-tagged Nef protein in native condition using heparin and immobilized metal ion affinity chromatographies.

scientific article

USP18 is a significant driver of memory CD4 T-cell reduced viability caused by type I IFN signaling during primary HIV-1 infection

scientific article published on 28 October 2019

Viral protein R upregulates expression of ULBP2 on uninfected bystander cells during HIV-1 infection of primary CD4+ T lymphocytes

scientific article published on May 31, 2013

Virus-Activated Interferon Regulatory Factor 7 Upregulates Expression of the Interferon-Regulated BST2 Gene Independently of Interferon Signaling

scientific article published on February 1, 2012

Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis

scientific article

Vpu Exerts a Positive Effect on HIV-1 Infectivity by Down-modulating CD4 Receptor Molecules at the Surface of HIV-1-producing Cells

scientific article published on May 13, 2003

Vpu Exploits the Cross-Talk between BST2 and the ILT7 Receptor to Suppress Anti-HIV-1 Responses by Plasmacytoid Dendritic Cells

scientific article published on 14 July 2015

miRNA-1236 inhibits HIV-1 infection of monocytes by repressing translation of cellular factor VprBP.

scientific article