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List of works by Amnon Albeck

"Switch off/switch on" regulation of drug cytotoxicity by conjugation to a cell targeting peptide

scientific article

A new method for filtering of reactive "warheads" of transition-state analog protease inhibitors

scientific article published on 28 February 2014

An unexpected rearrangement during mitsunobu epimerization reaction of sugar derivatives

scientific article

Anti-neoplastic activity of 1,3-diaza-2-functionalized-adamantan-6-one compounds against melanoma cells

scientific article published on January 2014

Application of EMBM to Structure-Based Design of Warheads for Protease Inhibitors

scientific article published on 24 October 2013

Biolabile peptidyl delivery systems toward sequential drug release.

scientific article published on 11 December 2015

Challenging a paradigm: theoretical calculations of the protonation state of the Cys25-His159 catalytic diad in free papain

scientific article

Controlling the pKa of the bacteriorhodopsin Schiff base by use of artificial retinal analogues

scientific article published on May 1986

Differentiating Serine and Cysteine Protease Mechanisms by New Covalent QSAR Descriptors ⬇️

scientific article published on March 24, 2011

Dual-drug RGD conjugates provide enhanced cytotoxicity to melanoma and non-small lung cancer cells

scientific article published on 30 December 2015

EMBM − A New Enzyme Mechanism-Based Method for Rational Design of Chemical Sites of Covalent Inhibitors ⬇️

scientific article published on November 19, 2010

Enzyme isoselective inhibitors: a tool for binding-trend analysis

scientific article

Enzyme isoselective inhibitors: application to drug design

scientific article published on 01 June 2006

Factors affecting the absorption maxima of acidic forms of bacteriorhodopsin. A study with artificial pigments

scientific article

Gas Phase Bond Formation in Dipeptide Clusters

scientific article published on 14 November 2020

How does the exosite of rhomboid protease affect substrate processing and inhibition?

scientific article published on 8 September 2017

Identification of protons position in acid-base enzyme catalyzed reactions: the hepatitis C viral NS3 protease

scientific article published on May 2004

Inactivation of cysteine proteases by peptidyl epoxides: characterization of the alkylation sites on the enzyme and the inactivator

scientific article published in February 2000

Is there a weak H-bond --> LBHB transition on tetrahedral complex formation in serine proteases?

scientific article published in February 2004

Ligand-Substitution Reactions of the Tellurium Compound AS-101 in Physiological Aqueous and Alcoholic Solutions

scientific article published on 11 October 2016

Mechanism of cysteine protease inactivation by peptidyl epoxides

scientific article published on March 1997

Multifunctional tellurium molecule protects and restores dopaminergic neurons in Parkinson's disease models

scientific article published on 21 February 2007

Neutral and positively charged thiols synergize the effect of the immunomodulator AS101 as a growth inhibitor of Jurkat cells, by increasing its uptake

scientific article published on 18 May 2007

Octa-O-bis-(R,R)-Tartarate Ditellurane (SAS) - a novel bioactive organotellurium(IV) compound: synthesis, characterization, and protease inhibitory activity

scientific article published on 01 November 2007

Peptidyl epoxides extended in the P' direction as cysteine protease inhibitors: effect on affinity and mechanism of inhibition

scientific article

Picosecond time-resolved absorption and fluorescence dynamics in the artificial bacteriorhodopsin pigment BR6.11.

scientific article

Screening of the active site from water by the incoming ligand triggers catalysis and inhibition in serine proteases

scientific article published in March 2008

Stepwise Versus Concerted Mechanisms in General-Base Catalysis by Serine Proteases.

scientific article

Structural and spatial considerations in the N,N'-diacyl- and bis(alkoxycarbonyl)bispidinone series

scientific article published on 04 September 2008

Synthesis of selectively labeled D-fructose and D-fructose phosphate analogues locked in the cyclic furanose form

scientific article published on 01 September 2000

Synthesis, biological studies and molecular dynamics of new anticancer RGD-based peptide conjugates for targeted drug delivery

scientific article published on 12 December 2015

Synthesis, drug release, and biological evaluation of new anticancer drug-bioconjugates containing somatostatin backbone cyclic analog as a targeting moiety

scientific article published on 8 June 2015

The Catalytic Machinery of Rhomboid Proteases: Combined MD and QM Simulations.

scientific article published on 2 October 2012

The cooperative effect between active site ionized groups and water desolvation controls the alteration of acid/base catalysis in serine proteases

scientific article published on 01 August 2007

The mechanism of papain inhibition by peptidyl aldehydes ⬇️

scientific article published on December 22, 2010

The synthetic tellurium compound, AS101, is a novel inhibitor of IL-1beta converting enzyme

scientific article published on 01 June 2007

α-Aminoisobutyric Acid Leads a Fluorescent syn-bimane LASER Probe Across the Blood-brain Barrier.

scientific article published on 17 May 2015

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