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List of works by Martin Blackledge

16-fold degeneracy of peptide plane orientations from residual dipolar couplings: analytical treatment and implications for protein structure determination

scientific article

A Combined NMR and SAXS Analysis of the Partially Folded Cataract-Associated V75D γD-Crystallin.

scientific article published on March 2017

A Unified Description of Intrinsically Disordered Protein Dynamics under Physiological Conditions Using NMR Spectroscopy

scientific article published on 22 October 2019

A self-consistent description of the conformational behavior of chemically denatured proteins from NMR and small angle scattering.

scientific article

A structural model for unfolded proteins from residual dipolar couplings and small-angle x-ray scattering.

scientific article

A thermodynamic switch modulates abscisic acid receptor sensitivity

scientific article

Accurate characterization of weak macromolecular interactions by titration of NMR residual dipolar couplings: application to the CD2AP SH3-C:ubiquitin complex

scientific article

Amino acid bulkiness defines the local conformations and dynamics of natively unfolded alpha-synuclein and tau

scientific article published on 23 February 2007

An intrinsically disordered proteins community for ELIXIR

scientific article published on 15 October 2019

An ultraweak interaction in the intrinsically disordered replication machinery is essential for measles virus function

scientific article published on 22 August 2018

Analytical Description of NMR Relaxation Highlights Correlated Dynamics in Intrinsically Disordered Proteins.

scientific article published on 22 August 2017

Anisotropic collective motion contributes to nuclear spin relaxation in crystalline proteins

scientific article published on 01 February 2010

Anisotropic small amplitude Peptide plane dynamics in proteins from residual dipolar couplings

scientific article published in April 2004

Assembly and cryo-EM structures of RNA-specific measles virus nucleocapsids provide mechanistic insight into paramyxoviral replication

scientific article published on 20 February 2019

Atomic resolution conformational dynamics of intrinsically disordered proteins from NMR spin relaxation.

scientific article published on 10 July 2017

Atomic resolution description of the interaction between the nucleoprotein and phosphoprotein of Hendra virus

scientific article published in 2013

Atomic-Resolution Structural Dynamics in Crystalline Proteins from NMR and Molecular Simulation

scientific article published on 27 November 2012

Binding Mechanisms of Intrinsically Disordered Proteins: Theory, Simulation, and Experiment

scientific article

Biophysical characterization of the MerP-like amino-terminal extension of the mercuric reductase from Ralstonia metallidurans CH34 ⬇️

scientific article published on November 18, 2003

Characterization of intrinsically disordered proteins and their dynamic complexes: From in vitro to cell-like environments

scientific article published on 31 July 2018

Characterization of protein dynamics from residual dipolar couplings using the three dimensional Gaussian axial fluctuation model

scientific article published on 01 April 2008

Characterization of the interactions between the nucleoprotein and the phosphoprotein of Henipavirus

scientific article

Characterizing Protein-Protein Interactions Using Solution NMR Spectroscopy

scientific article published in January 2018

Characterizing weak protein-protein complexes by NMR residual dipolar couplings.

scientific article published on 28 June 2011

Charge-induced molecular alignment of intrinsically disordered proteins

scientific article published on 01 October 2006

Conformational and thermodynamic changes of the repressor/DNA operator complex upon monomerization shed new light on regulation mechanisms of bacterial resistance against  -lactam antibiotics

scientific article

Conformational changes specific for pseudophosphorylation at serine 262 selectively impair binding of tau to microtubules

scientific article published in October 2009

Conformational distributions of unfolded polypeptides from novel NMR techniques

article published in 2008

Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.

scientific article

Conformational propensities of intrinsically disordered proteins from NMR chemical shifts

scientific article published on 21 June 2013

Cysteine oxidation and disulfide formation in the ribosomal exit tunnel

scientific article published on 04 November 2020

Deciphering the Dynamic Interaction Profile of an Intrinsically Disordered Protein by NMR Exchange Spectroscopy.

scientific article published on 25 December 2017

Defining Long-Range Order and Local Disorder in Native α-Synuclein Using Residual Dipolar Couplings

scientific article published on 01 December 2005

Defining conformational ensembles of intrinsically disordered and partially folded proteins directly from chemical shifts.

scientific article

Describing intrinsically disordered proteins at atomic resolution by NMR.

scientific article published on 29 March 2013

Direct Observation of Dipolar Couplings and Hydrogen Bonds across a β-Hairpin in 8 M Urea

scientific article published in 2007

Direct prediction of NMR residual dipolar couplings from the primary sequence of unfolded proteins

scientific article published on 28 November 2012

Direct structure determination using residual dipolar couplings: reaction-site conformation of methionine sulfoxide reductase in solution

scientific article published in November 2002

Disentangling the coil: modulation of conformational and dynamic properties by site-directed mutation in the non-native state of hen egg white lysozyme

scientific article

Distinct Ubiquitin Binding Modes Exhibited by SH3 Domains: Molecular Determinants and Functional Implications

scientific article

Domain conformation of tau protein studied by solution small-angle X-ray scattering

scientific article published on 5 September 2008

Dynamic Descriptions of Highly Flexible Molecules from NMR Dipolar Couplings: Physical Basis and Limitations.

scientific article published on 14 March 2017

Effect of the solvent on the conformation of a depsipeptide: NMR-derived solution structure of hormaomycin in DMSO from residual dipolar couplings in a novel DMSO-compatible alignment medium

scientific article published in February 2006

Elucidating binding mechanisms and dynamics of intrinsically disordered protein complexes using NMR spectroscopy

scholarly article by Robert Schneider published in October 2018

Enhanced conformational space sampling improves the prediction of chemical shifts in proteins

scientific article published on February 2010

Ensemble Calculation for Intrinsically Disordered Proteins Using NMR Parameters

scientific article published on January 2015

Ensemble Structure of the Highly Flexible Complex Formed between Vesicular Stomatitis Virus Unassembled Nucleoprotein and its Phosphoprotein Chaperone.

scientific article

Ensemble structure of the modular and flexible full-length vesicular stomatitis virus phosphoprotein

scientific article published on 9 July 2012

Exploring free-energy landscapes of intrinsically disordered proteins at atomic resolution using NMR spectroscopy

scientific article published on 11 April 2014

Exploring multiple timescale motions in protein GB3 using accelerated molecular dynamics and NMR spectroscopy

scientific article published on 22 March 2007

Exploring the Minimally Frustrated Energy Landscape of Unfolded ACBP

scientific article published on 07 November 2013

Flexible-meccano: a tool for the generation of explicit ensemble descriptions of intrinsically disordered proteins and their associated experimental observables.

scientific article published in June 2012

Functionally specific binding regions of microtubule-associated protein 2c exhibit distinct conformations and dynamics

scientific article published on 20 June 2018

H, C and N Backbone chemical shift assignments of the n-terminal and central intrinsically disordered domains of SARS-CoV-2 nucleoprotein

scientific article

H, C and N backbone chemical shift assignments of SARS-CoV-2 nsp3a

scientific article

Highly populated turn conformations in natively unfolded tau protein identified from residual dipolar couplings and molecular simulation

scientific article published on 27 March 2007

Identification of Dynamic Modes in an Intrinsically Disordered Protein Using Temperature-Dependent NMR Relaxation.

scientific article

Identification of slow correlated motions in proteins using residual dipolar and hydrogen-bond scalar couplings.

scientific article

Insights into the structure and dynamics of measles virus nucleocapsids by 1H-detected solid-state NMR.

scientific article

Intrinsic disorder in measles virus nucleocapsids.

scientific article

Intrinsic disorder within the erythrocyte binding-like proteins from Plasmodium falciparum

scientific article published on 5 October 2014

Intrinsic dynamics of the partly unstructured PX domain from the Sendai virus RNA polymerase cofactor P.

scientific article published on 22 June 2007

Intrinsically disordered proteins implicated in paramyxoviral replication machinery

scientific article published on 13 March 2014

Intrinsically disordered proteins: from sequence and conformational properties toward drug discovery

scientific article published on 13 April 2012

Investigating protein conformational energy landscapes and atomic resolution dynamics from NMR dipolar couplings: a review.

scientific article

Investigating the Role of Large-Scale Domain Dynamics in Protein-Protein Interactions

scientific article

Large-Scale Conformational Dynamics Control H5N1 Influenza Polymerase PB2 Binding to Importin α.

scientific article

Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications

Ligand-dependent dynamics of the active-site lid in bacterial dimethylarginine dimethylaminohydrolase.

scientific article published on 07 February 2014

Local dynamic amplitudes on the protein backbone from dipolar couplings: toward the elucidation of slower motions in biomolecules.

scientific article published in June 2004

Long-Range Correlated Dynamics in Intrinsically Disordered Proteins

article

Mapping Hidden Residual Structure within the Myc bHLH-LZ Domain Using Chemical Denaturant Titration

scientific article published on 08 August 2019

Mapping Protein Conformational Energy Landscapes Using NMR and Molecular Simulation ⬇️

scientific article published on May 23, 2013

Mapping the Conformational Landscape of Urea-Denatured Ubiquitin Using Residual Dipolar Couplings

scientific article published in 2007

Mapping the Native Conformational Ensemble of Proteins from a Combination of Simulations and Experiments: New Insight into the src-SH3 Domain

scientific article published on 24 May 2013

Mapping the conformational mobility of multidomain proteins

scientific article published on May 2010

Mapping the population of protein conformational energy sub-states from NMR dipolar couplings

scientific article published on 01 February 2013

Mapping the potential energy landscape of intrinsically disordered proteins at amino acid resolution

scientific article

Measles virus nucleo- and phosphoproteins form liquid-like phase-separated compartments that promote nucleocapsid assembly

scientific article published on 01 April 2020

Measurement and analysis of NMR residual dipolar couplings for the study of intrinsically disordered proteins

scientific article published in January 2012

Measurement of Site-Specific13C Spin−Lattice Relaxation in a Crystalline Protein

scientific article published in 2010

Modulation of structure and dynamics by disulfide bond formation in unfolded states

scientific article published on 28 March 2012

Modulation of the intrinsic helix propensity of an intrinsically disordered protein reveals long-range helix-helix interactions

scientific article

Molecular basis of host-adaptation interactions between influenza virus polymerase PB2 subunit and ANP32A

scientific article published on 21 July 2020

Mouse Rif1 is a regulatory subunit of protein phosphatase 1 (PP1).

scientific article published on 18 May 2017

Multi-Timescale Dynamics in Intrinsically Disordered Proteins from NMR Relaxation and Molecular Simulation.

scientific article published on 14 June 2016

Multi-timescale conformational dynamics of the SH3 domain of CD2-associated protein using NMR spectroscopy and accelerated molecular dynamics

scientific article published on 8 May 2012

NMR characterization of long-range order in intrinsically disordered proteins.

scientific article published in June 2010

NMR provides evidence for dynamic hydrogen bonding in proteins

scientific article published on 13 June 2007

NMR study of the interaction between Zn(II) ligated bleomycin and Streptoalloteichus hindustanus bleomycin resistance protein

scientific article published in January 2003

Nuclear magnetic resonance provides a quantitative description of protein conformational flexibility on physiologically important time scales.

scientific article published on 21 March 2011

Observation of heteronuclear overhauser effects confirms the 15N-1H dipolar relaxation mechanism in a crystalline protein

scientific article

On the origin of NMR dipolar waves in transient helical elements of partially folded proteins

scientific article published on 30 July 2008

PED in 2021: a major update of the protein ensemble database for intrinsically disordered proteins

scientific article published on 10 December 2020

Phosphorylation of human Tau protein by microtubule affinity-regulating kinase 2.

scientific article published on 22 November 2013

Pilotin-secretin recognition in the type II secretion system of Klebsiella oxytoca

scientific article

Plasticity of an ultrafast interaction between nucleoporins and nuclear transport receptors

scientific article published on 7 October 2015

Predictive atomic resolution descriptions of intrinsically disordered hTau40 and α-synuclein in solution from NMR and small angle scattering

scientific article published on 19 December 2013

Probing Protein Dynamics Using Multifield Variable Temperature NMR Relaxation and Molecular Dynamics Simulation

article

ProtSA: a web application for calculating sequence specific protein solvent accessibilities in the unfolded ensemble.

scientific article

Protein Dynamics from Multi-Field Variable Temperature NMR Relaxation and MD Simulation

article

Protein backbone dynamics from N-HN dipolar couplings in partially aligned systems: a comparison of motional models in the presence of structural noise

scientific article (publication date: April 2005)

Protein conformational flexibility from structure-free analysis of NMR dipolar couplings: quantitative and absolute determination of backbone motion in ubiquitin.

scientific article published in January 2009

Protein dynamics. Direct observation of hierarchical protein dynamics

scientific article

Quantitative Conformational Analysis of Functionally Important Electrostatic Interactions in the Intrinsically Disordered Region of Delta Subunit of Bacterial RNA Polymerase

scientific article published on 10 October 2019

Quantitative analysis of backbone dynamics in a crystalline protein from nitrogen-15 spin-lattice relaxation

article

Quantitative conformational analysis of partially folded proteins from residual dipolar couplings: application to the molecular recognition element of Sendai virus nucleoprotein

scientific article published on 29 May 2008

Quantitative description of backbone conformational sampling of unfolded proteins at amino acid resolution from NMR residual dipolar couplings.

scientific article published in December 2009

Quantitative determination of the conformational properties of partially folded and intrinsically disordered proteins using NMR dipolar couplings

scientific article published on September 2009

Quantitative modelfree analysis of urea binding to unfolded ubiquitin using a combination of small angle X-ray and neutron scattering.

scientific article

Reactivity, secondary structure, and molecular topology of the Escherichia coli sulfite reductase flavodoxin-like domain

scientific article

Relaxation-based structure refinement and backbone molecular dynamics of the dynein motor domain-associated light chain

scientific article

Remodeling of the conformational ensemble of the repeat domain of tau by an aggregation enhancer

scientific article published on 3 March 2016

Residual Dipolar Couplings in Short Peptides Reveal Systematic Conformational Preferences of Individual Amino Acids

scientific article published on 01 October 2006

Residual dipolar couplings measured in unfolded proteins are sensitive to amino-acid-specific geometries as well as local conformational sampling

scientific article published on October 2012

Revealing the mechanism of repressor inactivation during switching of a temperate bacteriophage

scientific article published on 11 August 2020

SAXS/SANS on Supercharged Proteins Reveals Residue-Specific Modifications of the Hydration Shell

scientific article

Self-Assembly of Measles Virus Nucleocapsid-like Particles: Kinetics and RNA Sequence Dependence.

scientific article published on 6 June 2016

Sequence-specific mapping of the interaction between urea and unfolded ubiquitin from ensemble analysis of NMR and small angle scattering data

scientific article

Sequence-specific solvent accessibilities of protein residues in unfolded protein ensembles.

scientific article published on 29 September 2006

Side chain orientation from methyl 1H-1H residual dipolar couplings measured in highly deuterated proteins

scientific article published in December 2002

Side-chain chi(1) conformations in urea-denatured ubiquitin and protein G from (3)J coupling constants and residual dipolar couplings

scientific article published in March 2010

Simultaneous definition of high resolution protein structure and backbone conformational dynamics using NMR residual dipolar couplings.

scientific article

Simultaneous determination of protein backbone structure and dynamics from residual dipolar couplings.

scientific article

Site-Specific Measurement of Slow Motions in Proteins

scientific article published in 2011

Site-specific backbone dynamics from a crystalline protein by solid-state NMR spectroscopy

scientific article published on 01 September 2004

Small-angle X-ray scattering- and nuclear magnetic resonance-derived conformational ensemble of the highly flexible antitoxin PaaA2

scientific article

Solution structure and dynamics of Crh, the Bacillus subtilis catabolite repression HPr

scientific article

Solution structure of the C-terminal X domain of the measles virus phosphoprotein and interaction with the intrinsically disordered C-terminal domain of the nucleoprotein

scientific article published in September 2010

Solution structure of the C-terminal nucleoprotein-RNA binding domain of the vesicular stomatitis virus phosphoprotein

scientific article

Solution structure of the sulfite reductase flavodoxin-like domain from Escherichia coli.

scientific article

Solution structure, dynamics and thermodynamics of the three SH3 domains of CD2AP.

scientific article

Solvent-dependent segmental dynamics in intrinsically disordered proteins.

scientific article published on 28 June 2019

Structural Characterization of the SMRT Corepressor Interacting with Histone Deacetylase 7.

scientific article

Structural Description of the Nipah Virus Phosphoprotein and Its Interaction with STAT1

scientific article published on 18 April 2020

Structural Impact of Proline-Directed Pseudophosphorylation at AT8, AT100, and PHF1 Epitopes on 441-Residue Tau ⬇️

scientific article published on September 15, 2011

Structural Impact of Tau Phosphorylation at Threonine 231.

scientific article published on 9 July 2015

Structural analysis of the complex between influenza B nucleoprotein and human importin-α.

scientific article published on 7 December 2017

Structural and Kinetic Characterization of the Intrinsically Disordered Protein SeV NTAIL through Enhanced Sampling Simulations.

scientific article published on 19 September 2017

Structural and biophysical characterization of murine rif1 C terminus reveals high specificity for DNA cruciform structures.

scientific article published on 14 March 2014

Structural and dynamics studies of a truncated variant of CI repressor from bacteriophage TP901-1

scientific article published on 12 July 2016

Structural biology turned on its head

scientific article published on 20 March 2015

Structural biology: Proteins in dynamic equilibrium.

scientific article

Structural characterization of alpha-synuclein in an aggregation prone state.

scientific article published on September 2009

Structural disorder within sendai virus nucleoprotein and phosphoprotein: insight into the structural basis of molecular recognition.

scientific article published on August 2010

Structural dynamics of protein backbone φ angles: extended molecular dynamics simulations versus experimental 3 J scalar couplings

article

Structure and Functions of Microtubule Associated Proteins Tau and MAP2c: Similarities and Differences

scientific article published on 16 March 2019

Structure and dynamics of the MKK7-JNK signaling complex

scientific article

Structure and dynamics of the nucleocapsid-binding domain of the Sendai virus phosphoprotein in solution

scientific article

Structure of Nipah virus unassembled nucleoprotein in complex with its viral chaperone

scientific article

Structure of the Tetramerization Domain of Measles Virus Phosphoprotein

scientific article

Structure of the Vesicular Stomatitis Virus N0-P Complex

scientific article

Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain.

scholarly article

Structure, Dynamics, and Kinetics of Weak Protein-Protein Complexes from NMR Spin Relaxation Measurements of Titrated Solutions

article

Structure, dynamics and phase separation of measles virus RNA replication machinery

scientific article published on 19 June 2020

Targeting the disordered C terminus of PTP1B with an allosteric inhibitor

scientific article

Testing the validity of ensemble descriptions of intrinsically disordered proteins

scientific article published on 17 March 2014

The LC8 Recognition Motif Preferentially Samples Polyproline II Structure in Its Free State.

scientific article published on 9 August 2017

The N(0)-binding region of the vesicular stomatitis virus phosphoprotein is globally disordered but contains transient α-helices

scientific article published on 16 February 2011

The Nucleoprotein and Phosphoprotein of Measles Virus

scientific article published on 21 August 2019

The Role of Dynamics and Allostery in the Inhibition of the eIF4E/eIF4G Translation Initiation Factor Complex

scientific article published on 10 May 2016

The Role of Dynamics and Allostery in the Inhibition of the eIF4E/eIF4G Translation Initiation Factor Complex

The influence of nitrogen-15 proton-driven spin diffusion on the measurement of nitrogen-15 longitudinal relaxation times

scientific article published on 09 October 2006

The intrinsically disordered SARS-CoV-2 nucleoprotein in dynamic complex with its viral partner nsp3a

scientific article

The role of (15)N CSA and CSA/dipole cross-correlation in (15)N relaxation in solid proteins

scientific article published on 20 January 2007

Toward a unified representation of protein structural dynamics in solution.

scientific article

Towards a robust description of intrinsic protein disorder using nuclear magnetic resonance spectroscopy.

scientific article published on 26 August 2011

Transient Electrostatic Interactions Dominate the Conformational Equilibrium Sampled by Multidomain Splicing Factor U2AF65: A Combined NMR and SAXS Study

scientific article published in 2014

Ultrahigh-Resolution Backbone Structure of Perdeuterated Protein GB1 Using Residual Dipolar Couplings from Two Alignment Media

scholarly article by Guillaume Bouvignies et al published 11 December 2006 in Angewandte Chemie International Edition

Ultrahigh-Resolution Backbone Structure of Perdeuterated Protein GB1 Using Residual Dipolar Couplings from Two Alignment Media

Vesicular Stomatitis Virus Phosphoprotein Dimerization Domain Is Dispensable for Virus Growth

scientific article published on 28 February 2020

Visualizing the molecular recognition trajectory of an intrinsically disordered protein using multinuclear relaxation dispersion NMR.

scientific article published on 16 January 2015

What's in a name? Why these proteins are intrinsically disordered: Why these proteins are intrinsically disordered

scientific article

pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins

scientific article

relax: the analysis of biomolecular kinetics and thermodynamics using NMR relaxation dispersion data

scientific article published on 01 October 2019

relax: the analysis of biomolecular kinetics and thermodynamics using NMR relaxation dispersion data.

scientific article

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