Search filters

List of works by Ruth Nussenzweig

A bicomponent Plasmodium falciparum investigational vaccine composed of protein-peptide conjugates.

scientific article

A circumsporozoite-like protein is present in micronemes of mature blood stages of malaria parasites

scientific article published in November 1989

A malaria vaccine based on a sporozoite antigen

scientific article published in January 1997

A striking property of recombinant poxviruses: efficient inducers of in vivo expansion of primed CD8(+) T cells

scientific article

A totally synthetic polyoxime malaria vaccine containing Plasmodium falciparum B cell and universal T cell epitopes elicits immune responses in volunteers of diverse HLA types

scientific article

Active immunization and passive transfer of resistance against sporozoite-induced malaria in infant mice

scientific article published in May 1981

Anophelines in the state of Acre, Brazil, infected with Plasmodium falciparum, P. vivax, the variant P. vivax VK247 and P. malariae

scientific article published in July 1993

Anti-malarial Effect of Interferon Inducers at Different Stages of Development of Plasmodium berghei in the Mouse ⬇️

scientific article published in November 1968

Antibodies against sporozoites of human and simian malaria produced in rats

scientific article published in February 1973

Antibodies against sporozoites of human and simian malaria produced in rats

scientific article published in August 1973

Antibodies to Plasmodium circumsporozoite protein (CSP) inhibit sporozoite's cell traversal activity ⬇️

scientific article published on January 28, 2012

Antibodies to Sporozoites: Their Frequent Occurrence in Individuals Living in an Area of Hyperendemic Malaria ⬇️

scientific article published on November 2, 1979

Antibodies to the protective antigen of Plasmodium berghei sporozoites prevent entry into cultured cells.

scientific article published in April 1982

Antibody-induced ultrastructural changes of malarial sporozoites ⬇️

scientific article published on March 1, 1976

Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses

scientific article

Antigenic analysis of the repeat domain of the circumsporozoite protein of Plasmodium vivax.

scientific article published in September 1987

Antisporozoite vaccine for malaria: experimental basis and current status.

scientific article published on May 1989

Biosynthesis of Pb44, the protective antigen of sporozoites of Plasmodium berghei

scientific article

CD4+ cytolytic T cell clone confers protection against murine malaria

scientific article

CD8+ cytolytic T cell clones derived against the Plasmodium yoelii circumsporozoite protein protect against malaria ⬇️

scientific article published on June 1, 1991

CS antigen localization in malaria vectors: hypothetical refractoriness to transmission observed in the field

scientific article published in August 1986

Cellular and humoral immune responses to a recombinant P. falciparum CS protein in sporozoite-immunized rodents and human volunteers

scientific article published on January 1990

Characterization of cross-reactive blood-stage antigens of the Plasmodium cynomolgi complex using anti-Plasmodium vivax monoclonal antibodies.

scientific article published on June 1988

Characterization of sporozoite surface antigens by indirect immunofluorescence: detection of stage- and species-specific antimalarial antibodies ⬇️

scientific article published on January 1, 1979

Characterization ofin VivoPrimary and Secondary CD8+T Cell Responses Induced by Recombinant Influenza and Vaccinia Viruses

article

Circumsporozoite gene of a Plasmodium falciparum strain from Thailand

scientific article published in July 1987

Circumsporozoite gene of plasmodium cynomolgi (Gombak):cDNA cloning and expression of the repetitive circumsporozoite epitope

scientific article published on December 1984

Circumsporozoite protein is required for development of malaria sporozoites in mosquitoes

scientific article published in January 1997

Circumsporozoite protein of Plasmodium gallinaceum characterized by monoclonal antibodies

scientific article published on September 1988

Circumsporozoite protein of Plasmodium vivax: gene cloning and characterization of the immunodominant epitope

scientific article published in November 1985

Circumsporozoite proteins of human malaria parasites Plasmodium falciparum and Plasmodium vivax

scientific article

Circumsporozoite proteins of malaria parasites

scientific article published on September 1985

Circumsporozoite proteins of malaria parasites

scientific article published in January 1989

Circumsporozoite proteins of malaria parasites contain a single immunodominant region with two or more identical epitopes ⬇️

scientific article published on June 1, 1983

Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria

scientific article published in September 1989

Cloning and expression in E. coli of the malarial sporozoite surface antigen gene from Plasmodium knowlesi ⬇️

scientific article published on April 7, 1983

Comparative studies on the immunogenicity of infective and attenuated sporozoites of Plasmodium berghei

scientific article published on January 1982

Complement alterations in rodent malaria

scientific article

Complement-mediated defect in clearance and sequestration of sensitized, autologous erythrocytes in rodent malaria

scientific article published on January 1981

Complete, long-lasting protection against malaria of mice primed and boosted with two distinct viral vectors expressing the same plasmodial antigen

scientific article

Congenital transfer of antibodies against malarial sporozoites detected in Gambian infants.

scientific article published in November 1981

Conserved group-specific epitopes of the circumsporozoite proteins revealed by antibodies to synthetic peptides.

scientific article published in May 1985

DNA Cloning of Plasmodium falciparum Circumsporozoite Gene: Amino Acid Sequence of Repetitive Epitope ⬇️

scientific article published on August 10, 1984

Delayed-type hypersensitivity in volunteers immunized with a synthetic multi-antigen peptide vaccine (PfCS-MAP1NYU) against Plasmodium falciparum sporozoites

scientific article published in March 2002

Demonstration of heat-shock protein 70 in the sporozoite stage of malaria parasites

scientific article published in January 1994

Detection and anatomical localization of Plasmodium falciparum circumsporozoite protein and sporozoites in the afrotropical malaria vector Anopheles gambiae s.l.

scientific article published in November 1987

Detection of anti-Plasmodium falciparum antibodies directed against a repetitive peptide of the gametocyte antigen Pfs2400 in malaria patients in Brazil.

scientific article

Development of Novel Influenza Virus Vaccines and Vectors ⬇️

scientific article published on August 1, 1997

Development of a sporozoite malaria vaccine

scientific article published in July 1986

Development of antimalaria immunity in mice lacking IFN-gamma receptor.

scientific article published in May 1995

Development of sporozoite vaccines ⬇️

scientific article published on November 13, 1984

Efficient induction of protective anti-malaria immunity by recombinant adenovirus

scientific article

Enhancement of a simian malarial infection (Plasmodium cynomolgi) in mosquitoes fed on rhesus (Macaca mulatta) previously infected with an unrelated malaria (Plasmodium knowlesi)

scientific article published on July 1, 1979

Erythrocyte membrane-associated immunoglobulins during malaria infection of mice ⬇️

scientific article published on July 1, 1977

Estimate of Plasmodium falciparum sporozoite content of Anopheles stephensi used to challenge human volunteers

scientific article published in February 1989

Evaluation of a Method for In vitro Ookinete Development of the Rodent Malarial Parasite, Plasmodium berghei

scientific article published on December 1, 1975

Exogenous Interferon protects Mice against Plasmodium berghei Malaria ⬇️

scientific article published on September 26, 1970

Experimental basis for the development of a synthetic vaccine against Plasmodium falciparum malaria sporozoites

scientific article published on January 1986

Freeze-Fracture Study of Malaria Sporozoites: Antibody-Induced Changes of the Pellicular Membrane* ⬇️

scientific article published on May 1, 1979

From the circumsporozoite protein to the RTS, S/AS candidate vaccine

scientific article published on 30 January 2010

Further Studies on the Plasmodium berghei-Anopheles stephensi: Rodent System of Mammalian Malaria

scientific article published in October 1968

Further studies on the antigenic diversity of the circumsporozoite proteins of the Plasmodium cynomolgi complex

scientific article published in May 1986

Further studies on the immunization of Saimiri sciureus boliviensis with recombinant vaccines based on the circumsporozoite protein of Plasmodium vivax

scientific article published in December 1990

Gamma delta T cells contribute to immunity against the liver stages of malaria in alpha beta T-cell-deficient mice

scientific article

Gamma interferon, CD8+ T cells and antibodies required for immunity to malaria sporozoites

scientific article published on December 1987

Gene targeting in the rodent malaria parasite Plasmodium yoelii

scientific article published in April 2001

Human CD8+ T cells mediate protective immunity induced by a human malaria vaccine in human immune system mice

scientific article published on 5 August 2016

Human immune system mice immunized with Plasmodium falciparum circumsporozoite protein induce protective human humoral immunity against malaria

scientific article published on 24 September 2015

Hybridoma produces protective antibodies directed against the sporozoite stage of malaria parasite

scientific article published in January 1980

Identification of Malaria-Infected Mosquitoes by a Two-Site Enzyme-Linked Immunosorbent Assay

scientific article published on March 1, 1984

Identification of circumsporozoite proteins in individual malaria-infected mosquitoes by Western blot analysis ⬇️

scientific article published on July 6, 1984

Identification of non-CSP antigens bearing CD8 epitopes in mice immunized with irradiated sporozoites

scientific article published on 30 July 2011

Immune phagocytosis in murine malaria ⬇️

scientific article published on June 1, 1979

Immunity to Plasmodium sporozoites: recent advances and applications to field research.

scientific article

Immunization against rodent malaria with cryopreserved irradiated sporozoites of Plasmodium berghei

scientific article published in May 1980

Immunization of Saimiri sciureus boliviensis with recombinant vaccines based on the circumsporozoite protein of Plasmodium vivax.

scientific article published in May 1989

Immuno-electron microscopic observations on Plasmodium knowlesi sporozoites: localization of protective antigen and its precursors

scientific article published on 01 March 1984

Immunofluorescent Staining of Exoerythrocytic Schizonts of Plasmodium berghei in Fixed Liver Tissue with Stage-Specific Immune Serum

scientific article published on December 1, 1978

Immunogenicity and infectivity of sporozoites of mammalian malaria isolated by density-gradient centrifugation

scientific article published in November 1973

Immunogenicity and protective efficacy of a recombinant yellow fever vaccine against the murine malarial parasite Plasmodium yoelii

scientific article

Immunogenicity of Ty-VLP bearing a CD8(+) T cell epitope of the CS protein of P. yoelii: enhanced memory response by boosting with recombinant vaccinia virus

scientific article published in June 2000

Immunogenicity of Ty-VLP bearing a CD8(+) T cell epitope of the CS protein of P. yoelii: enhanced memory response by boosting with recombinant vaccinia virus

scientific article published in March 2000

Immunogenicity of an alum-adsorbed synthetic multiple-antigen peptide based on B- and T-cell epitopes of the Plasmodium falciparum CS protein: possible vaccine application

scientific article published in August 1994

Immunogenicity of multiple antigen peptides containing B and non-repeat T cell epitopes of the circumsporozoite protein of Plasmodium falciparum ⬇️

scientific article published on February 15, 1993

Immunological studies in rodent malaria. I: Protective immunity induced in mice by mild strains of Plasmodium berghei yoelii against a virulent and fatal line of this plasmodium

scientific article published on September 1, 1975

Immunoprophylaxis of malaria: characterization of a protective surface antigen

scientific article published on January 1, 1982

Immunoradiometric assay to measure the in vitro penetration of sporozoites of malaria parasites into hepatoma cells

scientific article published in February 1985

Incorporation of T and B epitopes of the circumsporozoite protein in a chemically defined synthetic vaccine against malaria ⬇️

scientific article published on January 1, 1990

Increased nonspecific resstance to malaria produced by administration of killed Corynebacterium parvum

scientific article published in October 1967

Induction of protective immunity against malaria by priming-boosting immunization with recombinant cold-adapted influenza and modified vaccinia Ankara viruses expressing a CD8+-T-cell epitope derived from the circumsporozoite protein of Plasmodium y

scientific article published on November 2003

Induction of sporozoite-specific memory cells in mice immunized with a recombinant Plasmodium vivax circumsporozoite protein

scientific article published in December 1987

Influenza and vaccinia viruses expressing malaria CD8+ T and B cell epitopes. Comparison of their immunogenicity and capacity to induce protective immunity.

scientific article

Inhibition of Idiotype—Anti-Idiotype Interaction for Detection of a Parasite Antigen: a New Immunoassay ⬇️

scientific article published on March 26, 1982

Inhibition of development of exoerythrocytic forms of malaria parasites by gamma-interferon

scientific article published in May 1986

Inhibition of entry of Plasmodium falciparum and P. vivax sporozoites into cultured cells; an in vitro assay of protective antibodies ⬇️

scientific article published on February 1, 1984

Inhibitory activity against Plasmodium vivax sporozoites induced by plasma from Saimiri monkeys immunized with circumsporozoite recombinant proteins or irradiated sporozoites

scientific article published in July 1991

Interferon Inducers Protect Mice against Plasmodium berghei Malaria ⬇️

scientific article published in August 1968

Interferon-gamma inhibits the intrahepatocytic development of malaria parasites in vitro.

scientific article published in September 1987

Interferon-gamma responses are associated with resistance to reinfection with Plasmodium falciparum in young African children

scientific article published on April 1999

Interferon-gamma-independent CD8+ T cell-mediated protective anti-malaria immunity elicited by recombinant adenovirus

scientific article published in March 2000

Isolation and characterization of protective cytolytic T cells in a rodent malaria model system ⬇️

scientific article published on August 1, 1990

Laboratory assessment of a species-specific radioimmunoassay for the detection of malaria sporozoites in mosquitoes (Diptera: Culicidae).

scientific article published in March 1985

Levels of circumsporozoite protein in the Plasmodium oocyst determine sporozoite morphology

scientific article

Malaria vaccines: experience with sporozoite vaccines against falciparum malaria.

scientific article published in September 1988

Malaria vaccines: multiple targets

scientific article published on September 1994

Membrane-associated antigens of blood stages of Plasmodium, brasilianum, a quartan malaria parasite ⬇️

scientific article published on August 1, 1988

Membrane-bound antibodies to bloodstream Trypanosoma cruzi in mice: strain differences in susceptibility to complement-mediated lysis ⬇️

scientific article published on September 1, 1979

Monoclonal anti-gametocyte antibodies identify an antigen present in all blood stages of Plasmodium falciparum

scientific article published in June 1986

Monoclonal antibodies identify the protective antigens of sporozoites of Plasmodium knowlesi

scientific article

Monoclonal antibodies produced against sporozoites of the human parasite Plasmodium malariae abolish infectivity of sporozoites of the simian parasite Plasmodium brasilianum

scientific article published in October 1985

Monoclonal antibodies to Trypanosoma cruzi inhibit motility and nucleic acid synthesis of culture forms

scientific article

Monoclonal antibodies to circumsporozoite proteins identify the species of malaria parasite in infected mosquitoes

scientific article published in October 1982

Monoclonal antibody identifies circumsporozoite protein of Plasmodium malariae and detects a common epitope on Plasmodium brasilianum sporozoites.

scientific article

Monovalent fragments (Fab) of monoclonal antibodies to a sporozoite surface antigen (Pb44) protect mice against malarial infection

scientific article

Multiple T helper cell epitopes of the circumsporozoite protein of Plasmodium berghei

scientific article published in December 1988

Neutralization of the infectivity of sporozoites of Plasmodium knowlesi by antibodies to a synthetic peptide

scientific article

Parasitic disease as a cause of immunosuppression

scientific article published in February 1982

Pfs2400 can mediate antibody-dependent malaria transmission inhibition and may be the Plasmodium falciparum 11.1 gene product

scientific article

Phenotypic and functional properties of murine gamma delta T cell clones derived from malaria immunized, alpha beta T cell-deficient mice

scientific article published in March 1996

Plasmodium berghei sporozoites are mitogenic for murine T cells, induce interferon, and activate natural killer cells.

scientific article published in August 1984

Plasmodium berghei: Accelerated clearance of sporozoites from blood as part of immune-mechanism in mice ⬇️

scientific article published on February 1, 1972

Plasmodium berghei: Relationship between protective immunity and anti-sporozoite (CSP) antibody in mice ⬇️

scientific article published on February 1, 1973

Plasmodium berghei: T cell dependence of sporozoite-induced immunity in rodents ⬇️

scientific article published on June 1, 1977

Plasmodium berghei: suppression of antibody response to sporozoite stage by acute blood stage infection ⬇️

scientific article published on October 1, 1979

Plasmodium berghei: the spleen in sporozoite-induced immunity to mouse malaria

scientific article published on October 1, 1976

Plasmodium chabaudi and Plasmodium vinckei: phagocytic activity of mouse reticuloendothelial system

scientific article published in August 1969

Plasmodium falciparum polyoximes: highly immunogenic synthetic vaccines constructed by chemoselective ligation of repeat B-cell epitopes and a universal T-cell epitope of CS protein ⬇️

scientific article published on April 1, 1998

Plasmodium falciparum: Restricted polymorphism of T cell epitopes of the circumsporozoite protein in Brazil ⬇️

scientific article published on November 1, 1990

Plasmodium knowlesi sporozoite antigen: expression by infectious recombinant vaccinia virus

scientific article published in April 1984

Plasmodium yoelii: peptide immunization induces protective CD4+ T cells against a previously unrecognized cryptic epitope of the circumsporozoite protein

scientific article published in November 1996

Potential vectors of malaria and their different susceptibility to Plasmodium falciparum and Plasmodium vivax in northern Brazil identified by immunoassay

scientific article published in September 1986

Pre-erythrocytic malaria vaccine: mechanisms of protective immunity and human vaccine trials

scientific article

Preliminary studies on vaccination of rhesus monkeys with irradiated sporozoites of Plasmodium knowlesi and characterization of surface antigens of these parasites ⬇️

scientific article published on January 1, 1979

Presence of a circumsporozoite-like protein in micronemes of blood-stage merozoites of malaria parasites

scientific article published on January 1990

Prevalence and level of antibodies to the circumsporozoite proteins of human malaria parasites, including a variant of Plasmodium vivax, in the population of two epidemiologically distinct areas in the state of Acre, Brazil

scientific article published in January 1992

Prevalence and levels of antibodies to the circumsporozoite protein of Plasmodium falciparum in an endemic area and their relationship to resistance against malaria infection

scientific article published in January 1988

Priming with recombinant influenza virus followed by administration of recombinant vaccinia virus induces CD8+ T-cell-mediated protective immunity against malaria

scientific article

Progress in malaria vaccine development: characterization of protective antigens.

scientific article published in January 1982

Progress toward a malaria vaccine

scientific article published in September 1990

Progress toward a malaria vaccine: efficient induction of protective anti-malaria immunity

scientific article

Progress toward malaria preerythrocytic vaccines

scientific article published on April 1991

Protective Effect of Interferon Inducers on Plasmodium Berghei Malaria *

scientific article published in November 1969

Protective immunity produced by the injection of x-irradiated sporozoites of Plasmodium berghei. II. Effects of radiation on sporozoites.

scientific article published in December 1968

Rationale for development of a synthetic vaccine against plasmodium falciparum malaria

scientific article published in June 1985

Rationale for the development of an engineered sporozoite malaria vaccine

scientific article

Recent advances in the development of a sporozoite vaccine for malaria

scientific article published on December 1984

Recognition of different domains of the Plasmodium falciparum CS protein by the sera of naturally infected individuals compared with those of sporozoite-immunized volunteers ⬇️

scientific article published on October 15, 1992

Recombinant Sindbis Viruses Expressing a Cytotoxic T-Lymphocyte Epitope of a Malaria Parasite or of Influenza Virus Elicit Protection against the Corresponding Pathogen in Mice ⬇️

scientific article published on August 1, 1998

Recombinant proteins and synthetic peptides as malaria vaccine candidates.

scientific article

Recombinant viruses expressing a human malaria antigen can elicit potentially protective immune CD8+ responses in mice

scientific article

Research toward malaria vaccines

scientific article

Role of Anopheles culicifacies sibling species in malaria transmission in Madhya Pradesh state, India

scientific article published on November 1, 1992

Safety and enhanced immunogenicity of a hepatitis B core particle Plasmodium falciparum malaria vaccine formulated in adjuvant Montanide ISA 720 in a phase I trial

scientific article published on June 2005

Sero-epidemiological studies of malaria in Indian tribes and monkeys of the Amazon Basin of Brazil.

scientific article published in October 1989

Some characteristics of the immune response to sporozoites of simian and human malaria

scientific article published in January 1974

Specificity of the Circum-Sporozoite Precipitation Antigen(s) of Human and Simian Malarias

scientific article published on August 1, 1976

Sporozoite-induced immunity in mammalian malaria. A review.

scientific article

Sporozoites of Rodent and Simian Malaria, Purified by Anion Exchangers, Retain their Immunogenicity and Infectivity ⬇️

scientific article published on February 1, 1978

Sporozoites of mammalian malaria: attachment to, interiorization and fate within macrophages

scientific article published in May 1980

Stage-specific antigens on the surface membrane of sporozoites of malaria parasites ⬇️

scientific article published on July 6, 1978

Structural similarities among the protective antigens of sporozoites from different species of malaria parasites ⬇️

scientific article published on March 10, 1983

Structure of an immunodominant epitope of the circumsporozoite surface protein of Plasmodium knowlesi ⬇️

scientific article published on 01 November 1984

Structure of the plasmodium knowlesi gene coding for the circumsporozoite protein ⬇️

scientific article published on October 1, 1983

Studies on sporozoite-induced infections of rodent malaria. 3. The course of sporozoite-induced Plasmodium berghei in different hosts

scientific article published in September 1966

Subtle mutagenesis by ends-in recombination in malaria parasites

scientific article

Susceptibility of Anopheles culicifacies species A and B to Plasmodium vivax and Plasmodium falciparum as determined by immunoradiometric assay

scientific article published in January 1988

Synthetic malaria peptide vaccine elicits high levels of antibodies in vaccinees of defined HLA genotypes

scientific article published on 9 October 2000

Synthetic peptide vaccine confers protection against murine malaria

scientific article

T cell epitopes of the circumsporozoite protein of Plasmodium vivax. Recognition by lymphocytes of a sporozoite-immunized chimpanzee ⬇️

scientific article published on March 1, 1991

T cell responses to pre-erythrocytic stages of malaria: role in protection and vaccine development against pre-erythrocytic stages

scientific article

T cell responses to repeat and non-repeat regions of the circumsporozoite protein detected in volunteers immunized with Plasmodium falciparum sporozoites

scientific article

TLR5-dependent immunogenicity of a recombinant fusion protein containing an immunodominant epitope of malarial circumsporozoite protein and the FliC flagellin of Salmonella Typhimurium

scientific article published in August 2011

The Plasmodium eukaryotic initiation factor-2alpha kinase IK2 controls the latency of sporozoites in the mosquito salivary glands

scientific article

The antibody response to sporozoites of simian and human malaria parasites: its stage and species specificity and strain cross-reactivity ⬇️

scientific article published on January 1, 1974

The circumsporozoite gene of the Plasmodium cynomolgi complex

scientific article published on January 1987

The circumsporozoite protein is an immunodominant protective antigen in irradiated sporozoites

scientific article published on 6 December 2006

The in vivo cytotoxic activity of CD8+ T cell clones correlates with their levels of expression of adhesion molecules

scientific article

The protective antigen of malarial sporozoites (Plasmodium berghei) is a differentiation antigen.

scientific article published in June 1981

The relative contribution of antibodies, CD4+ and CD8+ T cells to sporozoite-induced protection against malaria

scientific article published in September 1993

The use of multiple antigen peptides in the analysis and induction of protective immune responses against infectious diseases.

scientific article published on January 1995

Ubiquity of the repetitive epitope of the CS protein in different isolates of human malaria parasites

scientific article published in October 1985

Ultrastructure of in Vitro Cultured Exoerythrocytic Stage of Plasmodium Berghei in a Hepatoma Cell Line

scientific article published on September 1, 1984

Variation of T cell epitopes of the Plasmodium falciparum CS protein: Its occurrence, extent and relevance ⬇️

scientific article published on August 1, 1990

Various characteristics of the immune response to sporozoites of simian and human malaria

scientific article published in December 1974

Widespread reactivity of human sera with a variant repeat of the circumsporozoite protein of Plasmodium vivax

Yellow fever 17D as a vaccine vector for microbial CTL epitopes

scientific article (publication date: 17 January 2005)

Paulina is supported by:

About Paulina

Help