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List of works by Kazuhiko Koike

A Case of an embedded clip in the gastric wall after shielding a post-endoscopic submucosal dissection ulcer with polyglycolic acid sheet

scientific article published on 21 June 2018

A Multicenter Open-Label Randomized Controlled Trial of Pancreatic Enzyme Replacement Therapy in Unresectable Pancreatic Cancer

scientific article published on 01 August 2018

A Multicenter Survey of the Management After Gastric Endoscopic Submucosal Dissection Related to Postoperative Bleeding ⬇️

scientific article published on September 8, 2011

A Novel Partially Covered Self-Expandable Metallic Stent with Proximal Flare in Patients with Malignant Gastric Outlet Obstruction

scientific article published on 17 February 2017

A R0 resection case of initially unresectable metastatic pancreatic cancer downstaged by FOLFIRINOX therapy

scientific article published on 01 August 2014

A case of disseminated nocardiosis followed by pneumocystis pneumonia in a patient prescribed corticosteroid and cyclosporin A and having elevated blood (1-->3)-beta-D-glucan

scientific article published in September 2009

A case of invasive central nervous system aspergillosis treated with micafungin with monitoring of micafungin concentrations in the cerebrospinal fluid.

scientific article published in January 2007

A case of pancreatic cancer after heart transplantation

scientific article published on 01 January 2012

A combination of serum anti- antibody titer and Kyoto classification score could provide a more accurate diagnosis of

A genetic polymorphism of CYP2C19 is associated with susceptibility to biliary tract cancer

scientific article published on 12 June 2010

A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region

scientific journal article

A large volume of visceral adipose tissue leads to severe acute pancreatitis.

scientific article published on 30 July 2011

A miRNA machinery component DDX20 controls NF-κB via microRNA-140 function ⬇️

scientific article published on March 16, 2012

A multicenter phase II trial of gemcitabine and candesartan combination therapy in patients with advanced pancreatic cancer: GECA2.

scientific article

A novel "hitch-and-ride" deep biliary cannulation method during rendezvous endoscopic ultrasound-guided ERCP technique

scientific article published on 21 July 2017

A novel basket catheter to facilitate endoscopic removal of pancreatic stones (with video)

scientific article published on 17 September 2013

A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion

scientific article

A novel, fully covered laser-cut nitinol stent with antimigration properties for nonresectable distal malignant biliary obstruction: a multicenter feasibility study.

scientific article

A patient with E. coli-induced pyelonephritis and sepsis who transiently exhibited symptoms associated with primary biliary cirrhosis.

scientific article published on November 2003

A phase I trial of gemcitabine, S-1 and LV combination (GSL) therapy in advanced pancreatic cancer

scientific article published on 21 August 2014

A phase II trial of gemcitabine, S-1 and LV combination (GSL) neoadjuvant chemotherapy for patients with borderline resectable and locally advanced pancreatic cancer

scientific article published on 30 May 2018

A pilot study of EUS-guided through-the-needle forceps biopsy (with video).

scientific article published on 6 January 2016

A potent therapeutics for gallbladder cancer by combinatorial inhibition of the MAPK and mTOR signaling networks.

scientific article published on 27 November 2015

A randomized controlled trial of sodium phosphate tablets and polyethylene glycol solution for polyp detection

scientific article published in July 2012

A randomized phase II study of gemcitabine and S-1 combination therapy versus gemcitabine monotherapy for advanced biliary tract cancer.

scientific article published on 26 January 2013

A retrospective analysis of early CA19‑9 change in salvage chemotherapy for refractory pancreatic cancer

scientific article published in December 2013

A retrospective study of S-1 and oxaliplatin combination chemotherapy in patients with refractory pancreatic cancer

scientific article published on 01 September 2013

A retrospective study of gemcitabine and cisplatin combination therapy as second-line treatment for advanced biliary tract cancer.

scientific article

A second-look endoscopy after endoscopic submucosal dissection for gastric epithelial neoplasm may be unnecessary: a retrospective analysis of postendoscopic submucosal dissection bleeding

scientific article published on 17 November 2009

A simple home-based self-monitoring tool for early detection of hand-foot syndrome in cancer patients.

scientific article

A single amino acid of toll-like receptor 4 that is pivotal for its signal transduction and subcellular localization

scientific article

Aberration in HBV genome and hepatocellular carcinoma

scientific article published in August 2004

Acoustic radiation force impulse elastography for noninvasive assessment of chronic pancreatitis

scientific article published on 09 November 2011

Acquisition of methicillin-resistant Staphylococcus aureus after living donor liver transplantation: a retrospective cohort study

scientific article

Acute Hepatitis E with Elevated Creatine Phosphokinase ⬇️

scientific article published on September 1, 2003

Acute Middle Gastrointestinal Bleeding Risk Associated with NSAIDs, Antithrombotic Drugs, and PPIs: A Multicenter Case-Control Study

scientific article

Acute hepatitis B of genotype H resulting in persistent infection

scientific article published on March 2014

Acute liver disease in Japan: a nationwide analysis of the Japanese Diagnosis Procedure Combination database

scientific article

Acute presentation of autoimmune hepatitis: a multicentre study with detailed histological evaluation in a large cohort of patients.

scientific article published on 20 April 2017

Adherence to oral chemotherapy medications among gastroenterological cancer patients visiting an outpatient clinic

scientific article published on 17 June 2017

Adhesive Interactions between Mononuclear Phagocytes and Intestinal Epithelium Perturb Normal Epithelial Differentiation and Serve as a Therapeutic Target in Inflammatory Bowel Disease

scientific article published on 01 November 2018

Adiponectin in chronic hepatitis C.

scientific article

Administration of angiotensin II, but not catecholamines, induces accumulation of lipids in the rat heart

scientific article

Adverse Events during Bowel Preparation and Colonoscopy in Patients with Acute Lower Gastrointestinal Bleeding Compared with Elective Non-Gastrointestinal Bleeding

scientific article

Adverse events associated with bidirectional endoscopy with midazolam and pethidine

scientific article published on 30 October 2019

Against duodenobiliary reflux: implications from a randomized controlled trial

scientific article published on 01 March 2016

Age-dependent PPARα activation induces hepatic sulfatide accumulation in transgenic mice carrying the hepatitis C virus core gene.

scientific article published on 18 June 2016

Alteration of intrahepatic cytokine expression and AP-1 activation in transgenic mice expressing hepatitis C virus core protein

scientific article published in December 2002

Altered composition of fatty acids exacerbates hepatotumorigenesis during activation of the phosphatidylinositol 3-kinase pathway.

scientific article published on 19 May 2011

Amino acid substitutions in the S region of hepatitis B virus in sera from patients with acute hepatitis

scientific article

Amphipathic α-helices in apolipoproteins are crucial to the formation of infectious hepatitis C virus particles

scientific article

An Unusual Case of Submucosal Tumor in the Stomach ⬇️

scientific article published on August 18, 2012

An effective technique for delivery of polyglycolic acid sheet after endoscopic submucosal dissection of the esophagus: the clip and pull method

scientific article published on 12 February 2014

Analysis of plasmid-mediated multidrug resistance in Escherichia coli and Klebsiella oxytoca isolates from clinical specimens in Japan.

scientific article

Analysis of predictive factors for R0 resection and immediate bleeding of cold snare polypectomy in colonoscopy

Anchor-wire technique for multiple plastic biliary stents to prevent stent dislocation ⬇️

scientific article published on July 28, 2011

Angiotensin II-induced regulation of the expression and localization of iron metabolism-related genes in the rat kidney.

scientific article published on February 2007

Animal models for hepatitis C and related liver disease

scientific article published in January 2010

Antagonism of sphingosine 1-phosphate receptor 2 causes a selective reduction of portal vein pressure in bile duct-ligated rodents.

scientific article published in October 2012

Anti-tumor activity of the proteasome inhibitor bortezomib in gastric cancer.

scientific article

Antireflux Metal Stent as a First-Line Metal Stent for Distal Malignant Biliary Obstruction: A Pilot Study

scientific article published on 13 June 2016

Antireflux metal stent with an antimigration system for distal malignant biliary obstruction: a feasibility pilot study

scientific article published in June 2015

Antithrombotic drug does not affect the positive predictive value of an immunochemical fecal occult blood test

scientific article

Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer

scientific article

Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase.

scientific article

Apoptosis signal-regulating kinase-1 inhibitor as a potent therapeutic drug for the treatment of gastric cancer.

scientific article

Application of loop-mediated isothermal amplification technique to rapid and direct detection of methicillin-resistant Staphylococcus aureus (MRSA) in blood cultures

scientific article published on 21 June 2007

Are serum carcinoembryonic antigen levels associated with carotid atherosclerosis in Japanese men?

scientific article published on 19 October 2007

Assessment of disease progression in patients with transfusion-associated chronic hepatitis C using transient elastography ⬇️

scientific article published on March 28, 2012

Association Between Colorectal Cancer and Atherosclerotic Diseases: A Study Using a National Inpatient Database in Japan.

scientific article published on February 2016

Association between autoimmune pancreatitis and malignancy

scientific article

Association between changes in obesity parameters and incidence of chronic kidney disease in Japanese individuals.

scientific article published on 30 April 2009

Association between chronic kidney disease and carotid intima-media thickening in individuals with hypertension and impaired glucose metabolism

scientific article published in November 2007

Association between cigarette smoking and chronic kidney disease in Japanese men.

scientific article published on March 2008

Association between colorectal polyps and hypertension treatment

scientific article published on 10 September 2015

Association between gamma-glutamyltransferase levels and insulin resistance according to alcohol consumption and number of cigarettes smoked

scientific article published on 13 March 2010

Association between gastric cancer and the Kyoto classification of gastritis

scientific article published on 20 February 2017

Association between hepatitis B/C viral infection, chronic kidney disease and insulin resistance in individuals undergoing general health screening

scientific article published on 25 March 2008

Association between metabolic syndrome and carotid atherosclerosis in individuals without diabetes based on the oral glucose tolerance test

scientific article

Association between obesity and chronic kidney disease in Japanese: differences in gender and hypertensive status?

scientific article published in November 2007

Atrophic gastritis and enlarged gastric folds diagnosed by double-contrast upper gastrointestinal barium X-ray radiography are useful to predict future gastric cancer development based on the 3-year prospective observation.

scientific article published on 20 October 2015

Autoimmune Pancreatitis With Low Serum Immunoglobulin G4 Level Associated With Annular Pancreas ⬇️

scientific article published on July 1, 2012

Autotaxin as a novel serum marker of liver fibrosis.

scientific article published on 17 March 2011

Background factors of reflux esophagitis and non-erosive reflux disease: a cross-sectional study of 10,837 subjects in Japan

scientific article published on 26 July 2013

Bacterial flagellin inhibits T cell receptor-mediated activation of T cells by inducing suppressor of cytokine signalling-1 (SOCS-1).

scientific article published in October 2006

Better stent function with chemotherapy: effects of chemotherapy or just a better prognosis? ⬇️

scientific article published on 01 May 2012

Bezafibrate for the treatment of primary sclerosing cholangitis

scientific article published on 3 February 2010

Bilateral Candida endophthalmitis accompanying Candida lusitaniae bloodstream infection: A case report.

scientific article published on 25 October 2017

Biliary cast syndrome and benign biliary stricture as complications of allogeneic hematopoietic stem cell transplantation

scientific article published on 30 March 2010

Biliary epithelial injury-induced regenerative response by IL-33 promotes cholangiocarcinogenesis from peribiliary glands

scientific article published on 24 April 2017

Biliary self-expandable metallic stent for unresectable malignant distal biliary obstruction: which is better: covered or uncovered?

scientific article published on May 2013

Biphasic regulation of levofloxacin on lipopolysaccharide-induced IL-1beta production

scientific article published on 23 January 2007

Bleeding after endoscopic sphincterotomy or papillary balloon dilation among users of antithrombotic agents

scientific article

Bleeding after endoscopic submucosal dissection: Risk factors and preventive methods

scientific article

Blocking CXCLs-CXCR2 axis in tumor-stromal interactions contributes to survival in a mouse model of pancreatic ductal adenocarcinoma through reduced cell invasion/migration and a shift of immune-inflammatory microenvironment

article by Makoto Sano et al published 18 January 2019 in Oncogenesis

Brain metastasis in pancreatic cancer: Two case reports

CA19-9 kinetics during systemic chemotherapy in patients with advanced or recurrent biliary tract cancer

scientific article published on 16 October 2017

CPT2 downregulation adapts HCC to lipid-rich environment and promotes carcinogenesis via acylcarnitine accumulation in obesity.

scientific article published on 6 February 2018

CT with hepatic arterioportography as a pretreatment examination for hepatocellular carcinoma patients: a randomized controlled trial.

scientific article published on 30 April 2013

CXCR4-expressing Mist1+ progenitors in the gastric antrum contribute to gastric cancer development.

scientific article published on 10 November 2017

Can the Abbott RealTime hepatitis C virus assay be used to predict therapeutic outcomes in hepatitis C virus-infected patients undergoing triple therapy?

scientific article

Can we develop self-expandable metallic stents without consideration of mechanical properties?

scientific article

Cancer preventive effect of pegylated interferon α-2b plus ribavirin in a real-life clinical setting in Japan: PERFECT interim analysis

scientific article published on June 28, 2011

Carcinogenesis of IPMN

scientific article published on 01 February 2012

Carnitine dynamics and their effects on hyperammonemia in cirrhotic Japanese patients.

scientific article

Categorization of upper gastrointestinal symptoms is useful in predicting background factors and studying effects and usages of digestive drugs

scientific article (publication date: 2014)

Cathepsin E is a marker of gastric differentiation and signet-ring cell carcinoma of stomach: a novel suggestion on gastric tumorigenesis

scientific article

Cause-specific mortality associated with aging in patients with hepatocellular carcinoma undergoing percutaneous radiofrequency ablation.

scientific article published on September 2014

Changes in levels of hepatitis B virus markers in patients positive for low-titer hepatitis B surface antigen

scientific article published on December 2012

Changes in risk of immediate adverse reactions to iodinated contrast media by repeated administrations in patients with hepatocellular carcinoma

scientific article

Changes in waist circumference and body mass index in relation to changes in serum uric acid in Japanese individuals

scientific article

Changing Nomenclature for PBC from "Primary Biliary Cirrhosis" to "Primary Biliary Cholangitis".

scientific article

Changing nomenclature for PBC from "Primary Biliary Cirrhosis" to "Primary Biliary Cholangitis".

scientific article published in January 2016

Changing nomenclature for PBC from "primary biliary cirrhosis" to "primary biliary cholangitis"

scientific article published on 01 July 2016

Characteristics of hepatocellular carcinoma nodules newly detected by computed tomography during arteriography and arterial portography: preliminary report of a randomized controlled trial

scientific article published on 31 August 2011

Characteristics of patients with nonalcoholic steatohepatitis who develop hepatocellular carcinoma.

scientific article

Characterization of SPP inhibitors suppressing propagation of HCV and protozoa.

scientific article published on 29 November 2017

Characterization of a new small bowel adenocarcinoma cell line and screening of anti-cancer drug against small bowel adenocarcinoma.

scientific article

Chlamydophilal antigens induce foam cell formation via c-Jun NH2-terminal kinase

scientific article published on 15 July 2007

Cholangitis complicated by infection of a simple hepatic cyst

scientific article published on 08 June 2018

Cholecystectomy after endoscopic papillary balloon dilation for bile duct stones reduced late biliary complications: a propensity score-based cohort analysis

scientific article published on 20 October 2015

Chronic hepatitis B in patients coinfected with human immunodeficiency virus in Japan: a retrospective multicenter analysis

scientific article published on 4 July 2012

Chronic hepatitis C in patients co-infected with human immunodeficiency virus in Japan: a retrospective multicenter analysis

scientific article published on 7 April 2009

Circulating AIM as an indicator of liver damage and hepatocellular carcinoma in humans

scientific article

Circulating RNAs as new biomarkers for detecting pancreatic cancer

scientific article

Clinical Importance of Non-alcoholic Fatty Liver Diseases. Topics: VIII. The prognosis and follow-up

scientific article published on January 2016

Clinical analysis of high serum IgE in autoimmune pancreatitis.

scientific article

Clinical and pathological progression of non-alcoholic steatohepatitis to hepatocellular carcinoma

scientific article published on 4 April 2012

Clinical benefit of radiation therapy and metallic stenting for unresectable hilar cholangiocarcinoma ⬇️

scientific article published on May 21, 2012

Clinical characteristics and survival outcomes of super-elderly hepatocellular carcinoma patients not indicated for surgical resection

scientific article published on 07 April 2015

Clinical characteristics of patients with diabetes mellitus and fatty liver diagnosed by liver/spleen Hounsfield units on CT scan

scientific article published on January 2017

Clinical characteristics, treatment, and prognosis of non-B, non-C hepatocellular carcinoma: a large retrospective multicenter cohort study.

scientific article

Clinical features of autoimmune hepatitis with acute presentation: a Japanese nationwide survey

scientific article published on 23 February 2018

Clinical outcomes of chemotherapy for diabetic and nondiabetic patients with pancreatic cancer: better prognosis with statin use in diabetic patients

scientific article published on 01 March 2013

Clinical outcomes of secondary gastroduodenal self-expandable metallic stent placement by stent-in-stent technique for malignant gastric outlet obstruction.

scientific article published on 28 August 2014

Clinical significance of bile cytology via an endoscopic nasobiliary drainage tube for pathological diagnosis of malignant biliary strictures

scientific article published on 01 March 2011

Clinical utility of an endoscopic ultrasound-guided rendezvous technique via various approach routes

scientific article published on 19 March 2013

Clinical utility of single-operator cholangiopancreatoscopy using a SpyGlass probe through an endoscopic retrograde cholangiopancreatography catheter

scientific article published on 01 August 2012

Coinfection of HBV and HIV

scientific article published on December 2015

Coinfection of HCV and HIV

scientific article published on December 2015

Coinfection of HIV with HCV

scientific article published on May 1, 2011

Colonoscopy reduces colorectal cancer mortality: A multicenter, long-term, colonoscopy-based cohort study.

scientific article published on 28 September 2017

Combined treatment with oral kanamycin and parenteral antibiotics for a case of persistent bacteremia and intestinal carriage with Campylobacter coli.

scientific article

Comorbidity, not age, is prognostic in patients with advanced pancreatic cancer receiving gemcitabine-based chemotherapy

scientific article published on 25 June 2010

Comparative analysis of upper gastrointestinal endoscopy, double-contrast upper gastrointestinal barium X-ray radiography, and the titer of serum anti-Helicobacter pylori IgG focusing on the diagnosis of atrophic gastritis.

scientific article published on 30 July 2015

Comparison of early and delayed EUS-guided drainage of pancreatic fluid collection

Comparison of the Impact of Changes in Waist Circumference and Body Mass Index in Relation to Changes in Serum Gamma-Glutamyltransferase Levels ⬇️

scientific article published on September 10, 2012

Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome

scientific article published on 9 April 2008

Complications related to gastric endoscopic submucosal dissection and their managements

scientific article

Computed tomography follow-up for the detection of hepatocellular carcinoma recurrence after initial radiofrequency ablation: a single-center experience

scientific article published on 01 October 2012

Conflicting clinical environment about the management of antithrombotic agents during the periendoscopic period in Japan.

scientific article published in September 2011

Confocal laser endomicroscopy in gastrointestinal and pancreatobiliary diseases

scientific article

Continuation or discontinuation of antithrombotics in clinical daily practice of gastrointestinal endoscopy: Has a paradigm shift occurred in Japan?

scientific article

Continuous negative pressure can improve endoscopic naso-pancreatic drainage

scientific article published on 06 December 2012

Continuous regional arterial infusion for acute pancreatitis: a propensity score analysis using a nationwide administrative database.

scientific article

Contrast-enhanced ultrasonographic image of gangrenous gallbladder

scientific article

Controversy on the management of anticoagulants and antiplatelet agents for scheduled endoscopy

scientific article

Conversion of transpapillary drainage to endoscopic ultrasound-guided hepaticogastrostomy and gallbladder drainage in a case of malignant biliary obstruction with recurrent cholangitis and cholecystitis (with videos).

scientific article published on May 2017

Conversion to endoscopic ultrasound-guided biliary drainage by temporary nasobiliary drainage placement in patients with prior biliary stenting

scientific article published on 8 February 2017

Cooperative contribution of gag substitutions to nelfinavir-dependent enhancement of precursor cleavage and replication of human immunodeficiency virus type-1.

scientific article

Correction: Prospective pilot study of fully covered self-expandable metal stents for refractory benign pancreatic duct strictures: long-term outcomes

scientific article published on November 2016

Covered biliary metal stent: which are worse—the concepts, current models, or insertion methods? ⬇️

scientific article published on 01 June 2011

Covered metallic stenting for malignant distal biliary obstruction: clinical results according to stent type ⬇️

scientific article published on September 1, 2011

Covered versus uncovered metal stents for malignant gastric outlet obstruction: Systematic review and meta-analysis

scientific article published on 20 December 2016

Crisscross anchor-stents to prevent metal stent migration during endoscopic ultrasound-guided hepaticogastrostomy

scientific article published on 19 November 2014

Critical role of PA28 in hepatitis C virus-associated steatogenesis and hepatocarcinogenesis

scientific article

Cryptococcal pleuritis containing a high level of adenosine deaminase in a patient with AIDS: a case report.

scientific article published on 29 April 2009

Cryptococcus gattii genotype VGIIa infection in man, Japan, 2007.

scientific article published in July 2010

Current status of chemotherapy for the treatment of advanced biliary tract cancer

scientific article published on 14 August 2013

Current status of chronic hepatitis B

scientific article published on 01 May 2011

Current status of miRNA-targeting therapeutics and preclinical studies against gastroenterological carcinoma

scientific article

Cystic duct patency in EUS-guided gallbladder drainage as a rescue treatment for malignant biliary obstruction

scientific article published in June 2016

DNA methylation at hepatitis B viral integrants is associated with methylation at flanking human genomic sequences

scientific article

Daclatasvir plus asunaprevir for chronic HCV genotype 1b infection

scientific article

Decline in perception of acid regurgitation symptoms from gastroesophageal reflux disease in diabetes mellitus patients.

scientific article published on 15 March 2018

Deconvoluting the composition of low-frequency hepatitis C viral quasispecies: comparison of genotypes and NS3 resistance-associated variants between HCV/HIV coinfected hemophiliacs and HCV monoinfected patients in Japan.

scientific article

Decrease in PSCA expression caused by Helicobacter pylori infection may promote progression to severe gastritis

scientific article published on 14 December 2017

Decreased miR122 in hepatocellular carcinoma leads to chemoresistance with increased arginine.

scientific article published on April 2015

Delineation of autoantibody repertoire through differential proteogenomics in hepatitis C virus-induced cryoglobulinemia

scientific article published on 12 July 2016

Dengue hemorrhagic fever in an adult traveler returning to Japan

scientific article published on July 2012

Dengue hemorrhagic shock and disseminated candidiasis.

scientific article

Depressive symptoms after treatment in hepatocellular carcinoma survivors: prevalence, determinants, and impact on health-related quality of life

scientific article published on 19 May 2013

Desirable training of endoscopic submucosal dissection: further spread worldwide

scientific article

Detection of painless pancreatitis by computed tomography in patients with post-endoscopic retrograde cholangiopancreatography hyperamylasemia

scientific article published on 23 November 2013

Detection of plasmid-mediated quinolone resistance associated with qnrA in an Escherichia coli clinical isolate producing CTX-M-9 beta-lactamase in Japan.

scientific article published on 18 January 2007

Development and evaluation of a loop-mediated isothermal amplification assay for rapid detection of Mycoplasma pneumoniae

scientific article

Development of a screening method to identify regulators of MICA shedding.

scientific article published on 20 August 2015

Development of pancreatic cancer is predictable well in advance using contrast-enhanced CT: a case-cohort study.

scientific article published on 19 June 2017

Diabetes is a useful diagnostic clue to improve the prognosis of pancreatic cancer.

scientific article

Diagnosis and therapy for attention-getting infections (discussion)

scientific article published in November 2007

Diagnostic accuracy of α-fetoprotein and des-γ-carboxy prothrombin in screening for hepatocellular carcinoma in liver transplant candidates

scientific article published on 15 September 2011

Diagnostic and therapeutic application of noncoding RNAs for hepatocellular carcinoma.

scientific article

Diagnostic capability of colon capsule endoscopy for advanced colorectal cancer: A pilot study.

scientific article published on 10 March 2017

Diagnostic yield of capsule endoscopy for gastric diseases ⬇️

scientific article published on 01 February 2012

Different subtypes of intraductal papillary mucinous neoplasm in the pancreas have distinct pathways to pancreatic cancer progression

scientific article published on 01 November 2011

Differential roles of ASK1 and TAK1 in Helicobacter pylori-induced cellular responses

scientific article published on 30 September 2013

Direct differentiation of hepatic cells from human induced pluripotent stem cells using a limited number of cytokines

scientific article published on 06 February 2011

Discrepancy in diagnosis of gastric submucosal tumor among esophagogastroduodenoscopy, CT, and endoscopic ultrasonography: a retrospective analysis of 93 consecutive cases.

scientific article published in December 2012

Discrimination of fibrotic staging of chronic hepatitis C using multiple fibrotic markers

scientific article published on 18 September 2013

Disease-specific mortality among patients with intraductal papillary mucinous neoplasm of the pancreas

scientific article published on 25 July 2013

Distinct chemopreventive effects of aspirin in diffuse and intestinal-type gastric cancer

scientific article published on 16 February 2018

Distribution of intestinal metaplasia as a predictor of gastric cancer development.

scientific article published on August 2015

Double-balloon enteroscope-assisted enteral stent placement for malignant afferent-loop obstruction after Roux-en-Y reconstruction

scientific article published on 19 November 2014

Drastically reduced neoplastic seeding related to radiofrequency ablation for hepatocellular carcinoma.

scientific article

Drug resistance in antiviral treatment for infections with hepatitis B and C viruses

scientific article published on 25 May 2007

Duodenal invasion is a risk factor for the early dysfunction of biliary metal stents in unresectable pancreatic cancer

scientific article published on 26 July 2011

Duodenal mass in a patient with weight loss and liver dysfunction. Duodenal and liver sarcoidosis

scientific article published on 2 August 2010

Duodenal metal stent placement is a risk factor for biliary metal stent dysfunction: an analysis using a time-dependent covariate

scientific article published on 17 October 2012

Dysfunction of autophagy participates in vacuole formation and cell death in cells replicating hepatitis C virus

scientific article published on 12 October 2011

ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development

scientific article published on 14 August 2014

EUS-FNA of gastric cancer metastatic to the head of pancreas using a forward oblique viewing echoendoscope in a case with Roux-en-Y anatomy

scientific article published on 01 November 2018

Early detection of gastric cancer after Helicobacter pylori eradication due to endoscopic surveillance

scientific article published on 20 June 2018

Early use of double-guidewire technique to facilitate selective bile duct cannulation: the multicenter randomized controlled EDUCATION trial

scientific article published on 15 January 2015

Eculizumab treatment for ischemic enteritis accompanied with paroxysmal nocturnal hemoglobinuria: a case report and literature review

scientific article published on 13 March 2018

Effect of nucleoside analog-interferon sequential therapy on patients with acute exacerbation of chronic hepatitis B.

scientific article published on 14 April 2010

Effect of treatment with interferon alpha-2b and ribavirin in patients infected with genotype 2 hepatitis C virus

scientific article

Effects of the AT(1) receptor blocker losartan and the calcium channel blocker benidipine on the accumulation of lipids in the kidney of a rat model of metabolic syndrome

scientific article published on 8 January 2010

Efficacy and safety of covered self-expandable metal stents for management of distal malignant biliary obstruction due to lymph node metastases.

scientific article published on 13 April 2011

Efficacy and safety of tenofovir disoproxil fumarate rescue therapy for chronic hepatitis B patients who failed other nucleos(t)ide analogs

scientific article published on 15 November 2016

Efficacy of Vonoprazan for Gastroesophageal Reflux Symptoms in Patients with Proton Pump Inhibitor-resistant Non-erosive Reflux Disease.

scientific article

Efficacy of flexible spectral imaging color enhancement on the detection of small intestinal diseases by capsule endoscopy ⬇️

scientific article published on December 1, 2012

Efficacy of repeat review with flexible spectral imaging color enhancement in patients with no findings by capsule endoscopy

scientific article

Efficacy of triple therapy with esomeprazole, amoxicillin, and sitafloxacin as a third-line Helicobacter pylori eradication regimen

scientific article

Electrohydraulic lithotripsy as a salvage option for stone impaction during double-balloon endoscope-assisted ERCP

scientific article published on 06 February 2016

Electrohydraulic lithotripsy of large bile duct stones under direct cholangioscopy with a double-balloon endoscope

scientific article published on 3 November 2015

Electrohydraulic lithotripsy under double-balloon endoscope-assisted direct cholangioscopy for treatment of choledocholithiasis in a patient with Roux-en-Y gastrectomy

scientific article published on 14 February 2018

Elevated plasma fibrinogen levels are associated with a poor prognosis in patients with hepatocellular carcinoma

scientific article published on 05 November 2013

Eltrombopag enables initiation and completion of pegylated interferon/ribavirin therapy in Japanese HCV-infected patients with chronic liver disease and thrombocytopenia.

scientific article published on 24 May 2019

Endoscopic bilateral metallic stenting for malignant hilar obstruction using newly designed stents

scientific article published on September 2011

Endoscopic management of bile duct stones in patients with surgically altered anatomy

scientific article published on 01 April 2018

Endoscopic management of biliary strictures after living donor liver transplantation

scientific article

Endoscopic management of colonic diverticular bleeding

scientific article published on 10 August 2015

Endoscopic management of combined malignant biliary and gastric outlet obstruction

scientific article published on 23 August 2016

Endoscopic management of the complications after acute pancreatitis.

scientific article

Endoscopic management with inside stent for proximal benign biliary stricture after laparoscopic cholecystectomy ⬇️

scientific article published on May 1, 2012

Endoscopic minor papilla balloon dilation for the treatment of symptomatic pancreas divisum

scientific article published on 01 August 2014

Endoscopic mucosal resection with a ligation device or endoscopic submucosal dissection for rectal carcinoid tumors: an analysis of 24 consecutive cases

scientific article published on 08 April 2012

Endoscopic papillary balloon dilation for bile duct stone removal in patients 60 years old or younger

scientific article published on 14 May 2010

Endoscopic papillary balloon dilation for bile duct stones in patients on hemodialysis.

scientific article published on 22 February 2012

Endoscopic papillary balloon dilation versus endoscopic sphincterotomy for bile duct stones: is it time to put a knife down?

scientific article published in May 2013

Endoscopic papillary large balloon dilation and endoscopic papillary balloon dilation both without sphincterotomy for removal of large bile duct stones: A propensity-matched analysis

scientific article published on 26 July 2018

Endoscopic removal of a proximally migrated pancreatic stent using a gooseneck snare.

scientific article published on 6 June 2014

Endoscopic removal of a spontaneously fractured biliary uncovered self-expandable metal stent

scientific article published on 01 May 2012

Endoscopic retrograde cholangiopancreatography for distal malignant biliary stricture.

scientific article published on 13 June 2012

Endoscopic submucosal dissection for superficial esophageal neoplasms ⬇️

scientific article published on May 16, 2012

Endoscopic submucosal dissection in a patient with esophageal adenoid cystic carcinoma

scientific article published in December 2017

Endoscopic submucosal dissection is an effective and safe therapy for early gastric neoplasms: a multicenter feasible study

scientific article published on 01 February 2012

Endoscopic tissue shielding method with polyglycolic acid sheets and fibrin glue to cover wounds after colorectal endoscopic submucosal dissection (with video).

scientific article published on 18 October 2013

Endoscopic transgastric pure NOTES cholecystectomy with naso-gallbladder drainage tube placement and injection of a hyaluronic acid mixture (with Video).

scientific article published on 17 June 2010

Endoscopic transpapillary gallbladder drainage with replacement of a covered self-expandable metal stent ⬇️

scientific article published on February 16, 2011

Endoscopic trimming of a migrated gastroduodenal stent using a loop cutter and a two-channel endoscope.

scientific article published on 14 October 2014

Endoscopic ultrasound-guided fine-needle aspiration for duodenal obstruction without a discrete mass.

scientific article published on 28 November 2014

Endoscopists should keep up with the current trends of antithrombotic therapy in other fields

scientific article

Engineering fibrotic tissue in pancreatic cancer: a novel three-dimensional model to investigate nanoparticle delivery.

scientific article published on 30 January 2012

Epidemiology and risk factors of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH).

scientific article published on January 2017

Eradication of hepatitis C virus is associated with the attenuation of steatosis as evaluated using a controlled attenuation parameter.

scientific article published on 18 May 2018

Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced MAPK signals

scientific article published in February 2013

Erratum: Corrigendum: MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma

scientific article published in Nature Communications

Estimation and comparison of cumulative incidences of biliary self-expandable metallic stent dysfunction accounting for competing risks.

scientific article published on 8 May 2013

Etiology and Long-term Rebleeding of Endoscopic Ulcerative Lesions in the Small Bowel in Patients with Obscure Gastrointestinal Bleeding: A Multicenter Cohort Study

scientific article published on 12 December 2017

Evaluation of a new image-enhanced endoscopic technology using band-limited light for detection of esophageal squamous cell carcinoma.

scientific article published on 29 April 2013

Evaluation of molecular targeted cancer drug by changes in tumor marker doubling times

scientific article published on 21 September 2011

Evaluation of preferable insertion routes for esophagogastroduodenoscopy using ultrathin endoscopes

scientific article

Evaluation of safety of endoscopic biopsy without cessation of antithrombotic agents in Japan

scientific article published on 18 February 2012

Expression of Gastric Markers Is Associated with Malignant Potential of Nonampullary Duodenal Adenocarcinoma

scientific article published on 28 June 2018

Expression of microRNA miR-122 facilitates an efficient replication in nonhepatic cells upon infection with hepatitis C virus

scientific article

Expression of α-taxilin in hepatocellular carcinoma correlates with growth activity and malignant potential of the tumor ⬇️

scientific article published on December 1, 2010

Extranodal NK/T-cell lymphoma of the nasal cavity developed in a patient with intestinal Epstein-Barr virus-positive T/NK-cell lymphoproliferative disorder

scientific article published on 22 May 2018

Factors affecting in-hospital mortality in patients with lower gastrointestinal tract bleeding: a retrospective study using a national database in Japan

scientific article published on 3 September 2014

Factors predicting adverse events associated with therapeutic colonoscopy for colorectal neoplasia: a retrospective nationwide study in Japan

scientific article

Factors predictive of inaccurate determination of horizontal extent of intestinal-type early gastric cancers during endoscopic submucosal dissection: a retrospective analysis.

scientific article published on 12 March 2013

Factors predictive of the efficacy of bezafibrate therapy in patients with primary sclerosing cholangitis

scientific article published on 17 January 2017

Fatal liver failure caused by reactivation of lamivudine-resistant hepatitis B virus: a case report

scientific article published on February 2007

Feasibility of a new self-expandable metallic stent for patients with malignant colorectal obstruction.

scientific article published on 9 July 2012

Feasibility of conversion of percutaneous cholecystostomy to internal transmural endoscopic ultrasound-guided gallbladder drainage

scientific article published in November 2017

Feasibility of spiral enteroscopy in Japanese patients: study in two tertiary hospitals

scientific article published on 05 December 2012

Feasibility study of gemcitabine and cisplatin combination chemotherapy for patients with refractory biliary tract cancer.

scientific article published on 6 July 2010

Fever-based antibiotic therapy for acute cholangitis following successful endoscopic biliary drainage.

scientific article published on 13 August 2011

Fibrosis score consisting of four serum markers successfully predicts pathological fibrotic stages of chronic hepatitis B

scientific article published on 07 November 2012

Foam plombage: a novel technique for optimal fixation of polyglycolic acid sheets positioned using "clip and pull" after esophageal endoscopic submucosal dissection.

scientific article published on 23 September 2015

Frequency of and predictive factors for vascular invasion after radiofrequency ablation for hepatocellular carcinoma.

scientific article

Frequency, risk factors and survival associated with an intrasubsegmental recurrence after radiofrequency ablation for hepatocellular carcinoma.

scientific article

Gastric Metaplasia Induced by Helicobacter pylori Is Associated with Enhanced SOX9 Expression via Interleukin-1 Signaling

scientific article

Gastric cancer cell line Hs746T harbors a splice site mutation of c-Met causing juxtamembrane domain deletion

scientific article published on 21 March 2010

Gastric cancer diagnosed after Helicobacter pylori eradication in diabetes mellitus patients.

scientific article published on 21 October 2015

Gastric cancer risk according to the distribution of intestinal metaplasia and neutrophil infiltration

scientific article published on 01 October 2011

Gastric polyps diagnosed by double-contrast upper gastrointestinal barium X-ray radiography mostly arise from the Helicobacter pylori-negative stomach with low risk of gastric cancer in Japan

scientific article published on 14 March 2016

Gemcitabine and S-1 versus gemcitabine and cisplatin treatment in patients with advanced biliary tract cancer: a multicenter retrospective study

scientific article

Gemcitabine and oxaliplatin combination chemotherapy for patients with refractory pancreatic cancer

scientific article published on 13 June 2011

Genome-wide association study identified new susceptible genetic variants in HLA class I region for hepatitis B virus-related hepatocellular carcinoma.

scientific article

Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma

scientific article published on 17 April 2011

Geographic distribution and characteristics of genotype A hepatitis B virus infection in acute and chronic hepatitis B patients in Japan

scientific article published on 25 June 2015

Gli regulates MUC5AC transcription in human gastrointestinal cells

scientific article

Groove Pancreatitis: Endoscopic Treatment via the Minor Papilla and Duct of Santorini Morphology

scientific article published on 8 December 2017

HBV DNA in serum of HBsAg-negative, anti-HBc-positive blood donors

scientific article published on 01 December 2002

HCV infection and lipid abnormalities

scientific article published on 01 May 2011

Helicobacter pylori infection is not associated with fatty liver disease including non-alcoholic fatty liver disease: a large-scale cross-sectional study in Japan.

scientific article

Helicobacter pylori infection is positively associated with gallstones: a large-scale cross-sectional study in Japan.

scientific article published on 5 June 2013

Hepatic IRS1 and ß-catenin expression is associated with histological progression and overt diabetes emergence in NAFLD patients.

scientific article

Hepatitis B virus pathogenesis: Fresh insights into hepatitis B virus RNA.

scientific article

Hepatitis C as a metabolic disease

scientific article published on 01 April 2012

Hepatitis C as a systemic disease: virus and host immunologic responses underlie hepatic and extrahepatic manifestations

scientific article

Hepatitis C virus NS5A protein promotes the lysosomal degradation of hepatocyte nuclear factor 1α via chaperone-mediated autophagy

scientific article published on 25 April 2018

Hepatitis C virus core protein activates ERK and p38 MAPK in cooperation with ethanol in transgenic mice

scientific article

Hepatitis C virus core protein compromises iron-induced activation of antioxidants in mice and HepG2 cells

scientific article published in May 2010

Hepatitis C virus core protein exerts an inhibitory effect on suppressor of cytokine signaling (SOCS)-1 gene expression

scientific article published on 31 May 2005

Hepatitis C virus core protein induces spontaneous and persistent activation of peroxisome proliferator-activated receptor alpha in transgenic mice: implications for HCV-associated hepatocarcinogenesis

scientific article published in January 2008

Hepatitis C virus core protein triggers abnormal porphyrin metabolism in human hepatocellular carcinoma cells.

scientific article published in June 2018

Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance

scientific article published on March 2004

Hepatocarcinogenesis in Hepatitis C: HCV Shrewdly Exacerbates Oxidative Stress by Modulating both Production and Scavenging of Reactive Oxygen Species ⬇️

scientific article published on December 22, 2011

Hepatocellular carcinoma in cirrhotic liver with graft-versus-host disease

scientific article published on 01 September 2012

Hepatocellular carcinoma with extrahepatic metastasis: clinical features and prognostic factors

scientific article published on 22 March 2011

High Alcohol Consumption Increases the Risk of Pancreatic Stone Formation and Pancreatic Atrophy in Autoimmune Pancreatitis ⬇️

scientific article published on 01 April 2013

High levels of hepatitis B virus after the onset of disease lead to chronic infection in patients with acute hepatitis B.

scientific article published on 23 May 2013

High single-session success rate of endoscopic bilateral stent-in-stent placement with modified large cell Niti-S stents for malignant hilar biliary obstruction.

scientific article

High ubiquitous mitochondrial creatine kinase expression in hepatocellular carcinoma denotes a poor prognosis with highly malignant potential.

scientific article

High-dose dexamethasone may prevent esophageal stricture after endoscopic submucosal dissection

scientific article published on 27 March 2010

Higher LPA2 and LPA6 mRNA Levels in Hepatocellular Carcinoma Are Associated with Poorer Differentiation, Microvascular Invasion and Earlier Recurrence with Higher Serum Autotaxin Levels

scientific article (publication date: September 2016)

Histologic intestinal metaplasia and endoscopic atrophy are predictors of gastric cancer development after Helicobacter pylori eradication.

scientific article published on 16 March 2016

Histone demethylase KDM4C regulates sphere formation by mediating the cross talk between Wnt and Notch pathways in colonic cancer cells.

scientific article published on 22 May 2013

IGF-II Producing Hepatocellular Carcinoma Treated with Sorafenib: Metabolic Complications and a Foresight to Molecular Targeting Therapy to the IGF Signal

scientific article

IL28B minor allele is associated with a younger age of onset of hepatocellular carcinoma in patients with chronic hepatitis C virus infection.

scientific article published on 22 May 2013

ISGF3 with reduced phosphorylation is associated with constitutive expression of interferon-induced genes in aging cells

article

Identification of a functional variant in the MICA promoter which regulates MICA expression and increases HCV-related hepatocellular carcinoma risk.

scientific article published on 11 April 2013

Identification of a novel mutation for phytosterolemia. Genetic analyses of 2 cases

scientific article published on 5 November 2008

Identification of hepatitis C virus genotype 2a replicon variants with reduced susceptibility to ribavirin

scientific article

Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling

scientific article

Identification of marker genes and pathways specific to precancerous duodenal adenomas and early stage adenocarcinomas

scientific article published on 28 June 2018

Idiopathic retroperitoneal fibrosis, inflammatory aortic aneurysm, and inflammatory pericarditis--retrospective analysis of 11 case histories

scientific article published on 09 December 2011

Impact of Changes in Obesity Parameters on Glucose Metabolism and Insulin Resistance Over a One-Year Period ⬇️

scientific article published on September 18, 2010

Impact of PNPLA3 polymorphisms on the development of hepatocellular carcinoma in patients with chronic hepatitis C virus infection.

scientific article published on 8 January 2014

Impact of Preoperative Biliary Drainage on Surgical Outcomes in Periampullary and Hilar Malignancy: A Single-Center Experience.

scientific article published on 2 February 2016

Impact of S-1 in patients with gemcitabine-refractory pancreatic cancer in Japan

scientific article published on 12 May 2010

Impact of S-1 on the survival of patients with advanced pancreatic cancer.

scientific article published in October 2010

Impact of fecal occult blood on obscure gastrointestinal bleeding: observational study

scientific article

Impact of hospital volume on outcomes in acute pancreatitis: a study using a nationwide administrative database

scientific article

Impact of introduction of wire-guided cannulation in therapeutic biliary endoscopic retrograde cholangiopancreatography.

scientific article

Impact of serum levels of interleukin-6 and adiponectin on all-cause, liver-related, and liver-unrelated mortality in chronic hepatitis C patients.

scientific article published on February 2015

Impacts of changes in obesity parameters for the prediction of blood pressure change in Japanese individuals

scientific article published on 03 December 2009

Improved survival with combined gemcitabine and S-1 for locally advanced pancreatic cancer: pooled analysis of three randomized studies

scientific article published on 13 June 2014

Improvement of prognosis for unresectable biliary tract cancer.

scientific article published on January 2013

In vitro selection of the 3'-untranslated regions of the human liver mRNA that bind to the HCV nonstructural protein 5B.

scientific article published on 18 December 2013

Incidence of Small Intestinal Lesions in Patients with Iron Deficiency Anemia

scientific article published on 01 July 2011

Incidence of extrapancreatic malignancies in patients with intraductal papillary mucinous neoplasms of the pancreas

scientific article published on 12 March 2011

Incidence of malignancies in patients with IgG4-related disease

article

Increased activity of serum mitochondrial isoenzyme of creatine kinase in hepatocellular carcinoma patients predominantly with recurrence.

scientific article

Increased serum autotaxin levels in hepatocellular carcinoma patients were caused by background liver fibrosis but not by carcinoma

scientific article published on 16 March 2014

Indications for endoscopic ultrasonography (EUS)-guided biliary intervention: Does EUS always come after failed endoscopic retrograde cholangiopancreatography?

scientific article published on 10 November 2016

Induction of p53-dependent p21 limits proliferative activity of rat hepatocytes in the presence of hepatocyte growth factor

scientific article (publication date: 2013)

Inflammation and de-differentiation in pancreatic carcinogenesis

article published in 2018

Inflammation-based prognostic scores predict disease severity in patients with acute cholecystitis

scientific article published on 4 January 2018

Influence of serum HBV DNA load on recurrence of hepatocellular carcinoma after treatment with percutaneous radiofrequency ablation

scientific article published on 25 January 2011

Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma ⬇️

scientific article published on September 19, 2011

Inhibition of autophagy exerts anti-colon cancer effects via apoptosis induced by p53 activation and ER stress.

scientific article published on 24 October 2015

Inhibition of microRNA122 decreases SREBP1 expression by modulating suppressor of cytokine signaling 3 expression.

scientific article published on 24 July 2013

Initial management for acute lower gastrointestinal bleeding

Interaction of hepatitis C virus core protein with retinoid X receptor alpha modulates its transcriptional activity

scientific article

Interstitial lung disease associated with gemcitabine: A Japanese retrospective cohort study

scientific article published on 2 November 2015

Intraductal papillary mucinous neoplasm was associated with pancreatic carcinogenesis, but not with systemic carcinogenesis

scientific article published on 08 May 2012

Intrahepatic bile duct dilatation after percutaneous radiofrequency ablation for hepatocellular carcinoma: impact on patient's prognosis.

scientific article published on 15 December 2010

Intrapancreatic biliary stricture in autoimmune pancreatitis should not be included in IgG4-related sclerosing cholangitis

scientific article published on 01 October 2014

Intravenous and intraperitoneal paclitaxel with S-1 for refractory pancreatic cancer with malignant ascites: an interim analysis

scientific article published on 01 September 2014

Intravenous and intraperitoneal paclitaxel with S-1 for treatment of refractory pancreatic cancer with malignant ascites

scientific article published on 23 June 2016

Invasion of poorly differentiated adenocarcinoma to the deep muscularis mucosae may be an indicator of lymph node metastasis in Barrett's esophageal cancer

scientific article

Involvement of the PA28 -Dependent Pathway in Insulin Resistance Induced by Hepatitis C Virus Core Protein

scientific article

Irsogladine improves small-intestinal injuries in regular users of nonsteroidal anti-inflammatory drugs

scientific article published on 8 February 2014

Is a guidewire a magic wand? Is a knife the final weapon?

scientific article published in January 2015

Is wire-guided selective bile duct cannulation effective for prevention of post-ERCP pancreatitis by all endoscopists?

scientific article published on 29 January 2014

Isocitrate dehydrogenase 1 mutation sensitizes intrahepatic cholangiocarcinoma to the BET inhibitor JQ1

article published in 2018

JSH Guidelines for the Management of Hepatitis C Virus Infection: A 2016 update for genotype 1 and 2.

scientific article

Japanese multicenter estimation of WallFlex duodenal stent for unresectable malignant gastric outlet obstruction

scientific article published on 26 April 2012

Japanese severity score for acute pancreatitis well predicts in-hospital mortality: a nationwide survey of 17,901 cases

scientific article published on 19 February 2013

LXR agonist increases apoE secretion from HepG2 spheroid, together with an increased production of VLDL and apoE-rich large HDL ⬇️

scientific article published on 05 August 2011

Lack in Standardized Reporting of Biliary Stents: A Meta-Analysis Complicated by the Inconsistency

scientific article published in May 2017

Laparoscopic and endoscopic cooperative surgery for gastrointestinal tumor

scientific article

Lifestyle factors affecting gastroesophageal reflux disease symptoms: a cross-sectional study of healthy 19864 adults using FSSG scores

scientific article

Lipid metabolism and liver disease in hepatitis C viral infection

scientific article published on 8 July 2010

Liver injury induced by the Japanese herbal drug kamishoyosan ⬇️

scientific article published on October 1, 2011

Liver lipid content is reduced in rat given 7-day administration of angiotensin II ⬇️

scientific article published on August 2, 2011

Living donor liver transplantations in HIV- and hepatitis C virus-coinfected hemophiliacs: experience in a single center.

scientific article published in June 2011

Living-donor liver transplantation for autoimmune hepatitis and autoimmune hepatitis-primary biliary cirrhosis overlap syndrome

scientific article published on May 2012

Loss of 5‐hydroxymethylcytosine is accompanied with malignant cellular transformation ⬇️

scientific article published on February 27, 2012

Loss of histone demethylase KDM6B enhances aggressiveness of pancreatic cancer through downregulation of C/EBPα.

scientific article

Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis

scientific article published on 06 January 2014

Lower incidence of biliary carcinoma in patients with primary sclerosing cholangitis and high serum levels of immunoglobulin E

scientific article published on 01 October 2011

MALT lymphoma of the small bowel with protein-losing enteropathy

scientific article published on 07 January 2014

Macrophage tolerance induced by stimulation with Toll-like receptor 7/8 ligands

scientific article

Magnifying endoscopy with narrow-band imaging helps determine the management of gastric adenomas ⬇️

scientific article published on January 18, 2012

Malignant peritoneal mesothelioma diagnosed by EUS-guided tissue acquisition

scientific article published in October 2015

Management of dysfunctional covered self-expandable metallic stents in patients with malignant distal biliary obstruction

scientific article published on 25 January 2013

Management of malignant gastric outlet obstruction with a modified triple-layer covered metal stent

scientific article published on 28 January 2012

Meandering main pancreatic duct as a relevant factor to the onset of idiopathic recurrent acute pancreatitis

scientific article

Mechanisms of drug resistance in hepatitis viruses B and C

scientific article published in February 2007

Meta-analysis: mortality and serious adverse events of peginterferon plus ribavirin therapy for chronic hepatitis C.

scientific article

Metabolic aspects of hepatitis C viral infection: steatohepatitis resembling but distinct from NASH.

scientific article

Metallic stent with high axial force as a risk factor for cholecystitis in distal malignant biliary obstruction

scientific article published in January 2014

Methylation status of suppressor of cytokine signaling-1 gene in hepatocellular carcinoma

scientific article

MicroRNA-140 acts as a liver tumor suppressor by controlling NF-κB activity by directly targeting DNA methyltransferase 1 (Dnmt1) expression.

scientific article

MicroRNA-22 and microRNA-140 suppress NF-κB activity by regulating the expression of NF-κB coactivators.

scientific article

MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma.

scientific article published on 7 June 2011

MicroRNAs and liver disease

scientific article published on 26 May 2016

Mitochondrial iron accumulation exacerbates hepatic toxicity caused by hepatitis C virus core protein

scientific article

Molecular basis for the synergy between alcohol and hepatitis C virus in hepatocarcinogenesis

scientific article published on March 2008

Molecular characterizations of carbapenem and ciprofloxacin resistance in clinical isolates of Pseudomonas putida

scientific article published in February 2009

Molecular epidemiology of hepatitis A virus in metropolitan areas in Japan

scientific article published in October 2006

Molecular mechanism of viral hepatocarcinogenesis

scientific article

Mortality and complication rates of percutaneous ablative techniques for the treatment of liver tumors: a systematic review

scientific article published on 20 August 2011

Mortality and hemorrhagic complications associated with radiofrequency ablation for treatment of hepatocellular carcinoma in patients on hemodialysis for end-stage renal disease: a nationwide survey

scientific article published on 7 March 2017

Mortality and morbidity of hepatectomy, radiofrequency ablation, and embolization for hepatocellular carcinoma: a national survey of 54,145 patients

scientific article published on 17 March 2012

Mucosal hyperplasia in an uncovered portion of partially covered metal stent ⬇️

scientific article published on September 16, 2012

Multicenter phase II study of S-1 monotherapy as second-line chemotherapy for advanced biliary tract cancer refractory to gemcitabine.

scientific article published on 6 October 2010

Multicenter retrospective and comparative study of 5-minute versus 15-second endoscopic papillary balloon dilation for removal of bile duct stones

scientific article published on 26 October 2017

Multiple metal stenting using a double-balloon endoscope for malignant biliary obstruction in a patient with hepaticojejunostomy.

scientific article published on 14 October 2014

Mutual antagonism between hepatitis B viral mRNA and host microRNA let-7.

scientific article published on 16 March 2016

Mutual reinforcement of inflammation and carcinogenesis by the Helicobacter pylori CagA oncoprotein

scientific article published on 6 May 2015

Narrow band imaging with magnification can pick up esophageal squamous cell carcinoma more efficiently than lugol chromoendoscopy in patients after chemoradiotherapy

scientific article published on 12 February 2013

Neutrophil infiltration and the distribution of intestinal metaplasia is associated with metachronous gastric cancer following endoscopic submucosal dissection

scientific article

New method of covered wallstents for distal malignant biliary obstruction to reduce early stent-related complications based on characteristics ⬇️

scientific article published on November 30, 2010

New method of endoscopic full-thickness resection: a pilot study of non-exposed endoscopic wall-inversion surgery in an ex vivo porcine model ⬇️

scientific article published on March 11, 2011

New predictive model of rebleeding during follow-up of patents with obscure gastrointestinal bleeding: A multicenter cohort study

scientific article published on 21 October 2015

New targeted therapies for gastric cancer ⬇️

scientific article published on March 16, 2011

Newly designed large cell Niti-S stent for malignant hilar biliary obstruction: a pilot study

scientific article published on 03 July 2010

Next endoscopic approach for acute lower gastrointestinal bleeding without an identified source on colonoscopy: upper or capsule endoscopy?

Nine primary malignant neoplasms-involving the esophagus, stomach, colon, rectum, prostate, and external ear canal-without microsatellite instability: a case report

scientific article published on 4 January 2018

No Association of Timing of Endoscopic Biliary Drainage with Clinical Outcomes in Patients with Non-severe Acute Cholangitis

scientific article published on 16 April 2018

No Survival Benefit from the Inhibition of Renin-Angiotensin System in Biliary Tract Cancer

scientific article published on 01 September 2016

No association of coffee consumption with gastric ulcer, duodenal ulcer, reflux esophagitis, and non-erosive reflux disease: a cross-sectional study of 8,013 healthy subjects in Japan

scientific article

No weekend effect on outcomes of severe acute pancreatitis in Japan: data from the diagnosis procedure combination database

scientific article

Non-exposed endoscopic wall-inversion surgery as a novel partial gastrectomy technique.

scientific article

Nonstructural 5A Protein of Hepatitis C Virus Interferes with Toll-Like Receptor Signaling and Suppresses the Interferon Response in Mouse Liver

scientific article

Novel antireflux covered metal stent for recurrent occlusion of biliary metal stents: a pilot study.

scientific article published on 29 April 2013

Novel sex-dependent differentially methylated regions are demethylated in adult male mouse livers

scientific article published on 8 May 2015

Novel technique for full-thickness resection of gastric malignancy: feasibility of nonexposed endoscopic wall-inversion surgery (news) in porcine models

scientific article published in December 2013

OR-THER-04: Long-term outcomes and reintervention of endoscopic ultrasound-guided biliary drainage for malignant biliary obstruction: A multicenter retrospective analysis of 96 cases

scientific article published in August 2017

One- and two-step self-expandable metal stent placement for distal malignant biliary obstruction: a propensity analysis

scientific article published on 20 April 2012

One-step, simultaneous triple endoscopic nasobiliary drainage for hilar biliary stricture.

scientific article published on 3 June 2012

Outcome of Long-term Maintenance Steroid Therapy Cessation in Patients With Autoimmune Pancreatitis: A Prospective Study

scientific article published on 12 November 2015

Oxidative stress and hepatitis C viral infection

scientific article published on 20 December 2005

PPARalpha activation is essential for HCV core protein-induced hepatic steatosis and hepatocellular carcinoma in mice

scientific article

Pancreas divisum as a predisposing factor for chronic and recurrent idiopathic pancreatitis: initial in vivo survey.

scientific article published on 15 February 2011

Pancreatic Lipomatous Hamartoma: A Hitherto Unrecognized Variant

scientific article published on 01 July 2018

Pancreatic cancer with malignant ascites: clinical features and outcomes.

scientific article

Pancreatic cysts: Is the answer on the wall?

scientific article published on 07 October 2018

Pathogenesis of lipid metabolism disorder in hepatitis C: polyunsaturated fatty acids counteract lipid alterations induced by the core protein

scientific article published on 22 September 2010

Pathological findings of nonalcoholic steatohepatitis and nonalcoholic fatty liver disease.

scientific article published on 20 December 2016

Percutaneous ethanol injection for hepatocellular carcinoma: 20-year outcome and prognostic factors

scientific article

Percutaneous transhepatic biliary drainage using a ligated catheter for recurrent catheter obstruction: antireflux technique

scientific article published on 14 March 2013

Percutaneous transhepatic cholangioscopy with an ultraslim video upper endoscope with CO2 insufflation: a feasibility study ⬇️

scientific article published on June 25, 2011

Percutaneous transhepatic cholangioscopy-assisted repositioning of misplaced endoscopic ultrasound-guided pancreatic duct stent

scientific article published in April 2016

Performance of autotaxin as a serum marker for liver fibrosis.

scientific article

Peribiliary Glands as the Cellular Origin of Biliary Tract Cancer.

scientific article published on 12 June 2018

Perihepatic lymph node enlargement is a negative predictor for sustained responses to pegylated interferon-α and ribavirin therapy for Japanese patients infected with hepatitis C virus genotype 1.

scientific article published on 29 January 2013

Perihepatic lymph node enlargement is a negative predictor of liver cancer development in chronic hepatitis C patients

scientific article published on 12 July 2012

Perihepatic lymph node enlargement observed at a general health examination: A cross-sectional study.

scientific article published on 20 December 2012

Phase I study on the safety, pharmacokinetic profile, and efficacy of the combination of TSU-68, an oral antiangiogenic agent, and S-1 in patients with advanced hepatocellular carcinoma

scientific article

Phase I trial of gemcitabine and candesartan combination therapy in normotensive patients with advanced pancreatic cancer: GECA1

scientific article published on 15 June 2012

Placement of multiple metal stents for malignant intrahepatic biliary obstruction via an endoscopic ultrasound-guided choledochoduodenostomy fistula

scientific article published on 10 October 2015

Plant sterols increased IL-6 and TNF-α secretion from macrophages, but to a lesser extent than cholesterol

scientific article published on 22 January 2011

Plasma concentration of bioactive lipid mediator sphingosine 1-phosphate is reduced in patients with chronic hepatitis C.

scientific article published on 24 February 2010

Plasma lysophosphatidic acid levels and hepatocellular carcinoma

scientific article published on 01 January 2013

Polyglycolic acid sheets and fibrin glue decrease the risk of bleeding after endoscopic submucosal dissection of gastric neoplasms (with video)

scientific article published on 29 October 2014

Postprandial fullness correlates with rapid inflow of gastric content into duodenum but not with chronic gastritis.

scientific article

Potential associations between perihepatic lymph node enlargement and liver fibrosis, hepatocellular injury or hepatocarcinogenesis in chronic hepatitis B virus infection

scientific article published on 16 June 2014

Prediction of hepatocellular carcinoma development by plasma ADAMTS13 in chronic hepatitis B and C.

scientific article published on 29 August 2011

Predictive factors of solid food intake in patients with malignant gastric outlet obstruction receiving self-expandable metallic stents for palliation

scientific article published on 16 November 2011

Preliminary report on a new, fully covered, metal stent designed for the treatment of pancreatic fluid collections.

scientific article published on 26 February 2013

Preoperative biliary drainage using a fully covered self-expandable metallic stent for pancreatic head cancer: A prospective feasibility study.

scientific article published in May 2018

Preoperative iodine staining may complicate the demarcation of esophageal carcinoma

scientific article published on 11 July 2013

Pretreatment prediction of the outcome of response-guided peginterferon-α and ribavirin therapy for chronic hepatitis C.

scientific article

Prevalence of Pancreatic Cystic Lesions Is Associated With Diabetes Mellitus and Obesity: An Analysis of 5296 Individuals Who Underwent a Preventive Medical Examination

scientific article published on 01 July 2017

Prevalence of coinfection with human immunodeficiency virus and hepatitis C virus in Japan

scientific article

Prevalence of hepatitis B virus infection in Japanese patients with HIV.

scientific article published on 17 September 2007

Prevalence of pks-positive Escherichia coli in Japanese patients with or without colorectal cancer

scientific article

Preventing esophageal stricture after endoscopic submucosal dissection: steroid injection and shielding with polyglycolic acid sheets and fibrin glue.

scientific article published on 14 October 2015

Preventive measures against stricture after esophageal endoscopic submucosal dissection: Halfway through the journey to the best method

scientific article published on 01 September 2018

Primary gastrointestinal follicular lymphoma with histological transformation

scientific article published on 28 December 2012

Procalcitonin is a useful biomarker to predict severe acute cholangitis: a single-center prospective study

scientific article

Prognostic factors in patients with advanced biliary tract cancer receiving chemotherapy

scientific article published on 20 June 2010

Progress and perspective in HBV research

scientific article published on 01 May 2011

Progress and perspective in HCV research

scientific article published on 01 May 2011

Progression-free survival as a surrogate for overall survival in first-line chemotherapy for advanced pancreatic cancer.

scientific article published on 20 July 2016

Prolonged treatment with pegylated interferon alpha 2b plus ribavirin improves sustained virological response in chronic hepatitis C genotype 1 patients with late response in a clinical real-life setting in Japan

scientific article published on 25 September 2009

Prospective pilot study of fully covered self-expandable metal stents for refractory benign pancreatic duct strictures: long-term outcomes

scientific article

Prospective single-arm trial of two-week rabeprazole treatment for ulcer healing after gastric endoscopic submucosal dissection

scientific article published on 13 July 2011

Prospective study of bezafibrate for the treatment of primary sclerosing cholangitis

scientific article published on 14 July 2015

Proteasome activator PA28gamma-dependent nuclear retention and degradation of hepatitis C virus core protein

scientific article

Proteomics analysis of mitochondrial proteins reveals overexpression of a mitochondrial protein chaperon, prohibitin, in cells expressing hepatitis C virus core protein

scientific article

Pseudorandomization using an instrumental variable: a strong tool to break through selection bias ⬇️

scientific article published on November 1, 2012

Pulse-wave velocity, the ankle-brachial index, and the visceral fat area are highly associated with colorectal adenoma

scientific article published on 19 June 2014

Quantitation of circulating satellite RNAs in pancreatic cancer patients

scientific article published on 2 June 2016

RASAL1 is a potent regulator of hepatic stellate cell activity and liver fibrosis

scientific article published on 4 May 2017

RNA-dependent RNA polymerase of hepatitis C virus binds to its coding region RNA stem-loop structure, 5BSL3.2, and its negative strand

scientific article published on 6 January 2010

ROCK inhibition enhances microRNA function by promoting deadenylation of targeted mRNAs via increasing PAIP2 expression

scientific article

Radiofrequency ablation for colorectal liver metastasis: 10-year outcome and future perspective

scientific article published in March 2013

Radiofrequency ablation for hepatocellular carcinoma: 10-year outcome and prognostic factors.

scientific article

Randomized controlled trial comparing the efficacy of mosapride plus omeprazole combination therapy to omeprazole monotherapy in gastroesophageal reflux disease

scientific article published on September 2014

Randomized prospective study showing the non-inferiority of tenofovir to entecavir in treatment-naïve chronic hepatitis B patients

scientific article

Rapid and sensitive detection of early esophageal squamous cell carcinoma with fluorescence probe targeting dipeptidylpeptidase IV

scientific article

Rarity of severe bleeding and perforation in endoscopic ultrasound-guided fine needle aspiration for submucosal tumors

scientific article published on 22 May 2013

Rebamipide induces dendritic cell recruitment to N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-exposed rat gastric mucosa based on IL-1β upregulation

scientific article

Recent Development of Techniques and Devices in Colorectal Endoscopic Submucosal Dissection

scientific article published on 30 November 2017

Recent progress and limitations of chemotherapy for pancreatic and biliary tract cancers ⬇️

scientific article published on March 10, 2011

Recent progress in endoscopic ultrasonography guided biliary intervention

scientific article

Receptor for activated protein kinase C: requirement for efficient microRNA function and reduced expression in hepatocellular carcinoma.

scientific article

Reduced expression of RAS protein activator like-1 in gastric cancer

scientific article published on 01 March 2011

Regulation of the expression of the liver cancer susceptibility gene MICA by microRNAs.

scientific article published on January 2013

Relationship between albuminuria, low eGFR, and carotid atherosclerosis in Japanese women

scientific article published on 14 May 2008

Relationship between smoking, white blood cell count and metabolic syndrome in Japanese women

scientific article published on 13 March 2007

Relationship between the initial dose of micafungin and its efficacy in patients with candidemia

scientific article published on 27 August 2007

Relationship of muscle cramps to quality of life and sleep disturbance in patients with chronic liver diseases: a nationwide study.

scientific article

Resistance mutations of hepatitis B virus in entecavir-refractory patients

scientific article published on 9 March 2017

Response

Response

scientific article published on 01 July 2015

Response

scientific article published on 15 July 2016

Response criteria of tolvaptan for the treatment of hepatic edema

scientific article

Results of the Tokyo trial of prevention of post-ERCP pancreatitis with risperidone-2: a multicenter, randomized, placebo-controlled, double-blind clinical trial

scientific article published on 30 July 2013

Retrospective analysis on the management of anticoagulants and antiplatelet agents for scheduled endoscopy

scientific article published on 10 September 2009

Reversal periods and patterns from drug-resistant to wild-type HIV type 1 after cessation of anti-HIV therapy

scientific article published on 01 January 2007

Risk factors and early signs of pancreatic cancer in diabetes: screening strategy based on diabetes onset age

scientific article published on 28 June 2012

Risk factors for covered metallic stent migration in patients with distal malignant biliary obstruction due to pancreatic cancer

scientific article published on 01 September 2014

Risk factors for pancreatitis following transpapillary self-expandable metal stent placement.

scientific article published on 20 October 2011

Risk factors for post-ERCP pancreatitis in wire-guided cannulation for therapeutic biliary ERCP

scientific article published on 05 November 2014

Risk factors for retinopathy associated with interferon alpha-2b and ribavirin combination therapy in patients with chronic hepatitis C.

scientific article

Risk factors for small bowel angioectasia: The impact of visceral fat accumulation

scientific article published on June 2015

Risk for mortality from causes other than pancreatic cancer in patients with intraductal papillary mucinous neoplasm of the pancreas.

scientific article

Role of Interleukin-32 in Helicobacter pylori-Induced Gastric Inflammation ⬇️

scientific article published on August 13, 2012

Role of endoscopic ultrasonography in pancreatic cystic neoplasms: where do we stand and where will we go?

scientific article

Role of hepatitis C virus in the development of hepatocellular carcinoma: transgenic approach to viral hepatocarcinogenesis

scientific article

Role of intervention for biliary and gastric/intestinal obstruction in gastric cancer with peritoneal metastasis ⬇️

scientific article published on December 1, 2012

Role of type II topoisomerase mutations and AcrAB efflux pump in fluoroquinolone-resistant clinical isolates of Proteus mirabilis

scientific article published on 26 July 2006

Safety and effectiveness of a long, partially covered metal stent for endoscopic ultrasound-guided hepaticogastrostomy in patients with malignant biliary obstruction

scientific article published on 7 October 2016

Safety and efficacy of colorectal endoscopic submucosal dissection by the trainee endoscopists ⬇️

scientific article published on May 1, 2012

Safety of Regular-Dose Imatinib Therapy in Patients with Gastrointestinal Stromal Tumors Undergoing Dialysis

scientific article

Santorinicele without pancreas divisum pathophysiology: initial clinical and radiographic investigations.

scientific article

Sarcopenia, intramuscular fat deposition, and visceral adiposity independently predict the outcomes of hepatocellular carcinoma.

scientific article published on 24 February 2015

Satellite RNA Increases DNA Damage and Accelerates Tumor Formation in Mouse Models of Pancreatic Cancer

scientific article published on 10 May 2018

Satellite RNAs promote pancreatic oncogenic processes via the dysfunction of YBX1.

scientific article published on 26 September 2016

Scheduled second-look endoscopy is not recommended after endoscopic submucosal dissection for gastric neoplasms (the SAFE trial): a multicentre prospective randomised controlled non-inferiority trial

scientific article published on 09 October 2014

Second-line chemotherapy in patients with advanced or recurrent biliary tract cancer: a single center, retrospective analysis of 294 cases

scientific article published on 15 October 2018

Sensitivity analysis, not a calculation of sensitivity, is essential in a propensity score analysis ⬇️

scientific article published on 01 June 2012

Serum Alpha-Fetoprotein Has High Specificity for the Early Detection of Hepatocellular Carcinoma After Hepatitis C Virus Eradication in Patients

scientific article

Serum anti- antibody titer and its association with gastric nodularity, atrophy, and age: A cross-sectional study

article published in 2018

Serum gamma-glutamyltransferase level is associated with serum superoxide dismutase activity and metabolic syndrome in a Japanese population

scientific article published on 06 October 2011

Serum level of adiponectin and the risk of liver cancer development in chronic hepatitis C patients

scientific article published on 29 March 2011

Serum levels of IgG4 and soluble interleukin-2 receptor in patients with coronary artery disease

scientific article published on 29 November 2011

Serum lipid profile of patients with genotype 1b hepatitis C viral infection in Japan ⬇️

scientific article published on 01 April 2003

Sessile serrated adenoma detection rate is correlated with adenoma detection rate.

scientific article published in March 2018

Severe bleeding after percutaneous transhepatic drainage of the biliary system: effect of antithrombotic agents--analysis of 34 606 cases from a Japanese nationwide administrative database

scientific article published on 05 September 2014

Severe bleeding and perforation are rare complications of endoscopic ultrasound-guided fine needle aspiration for pancreatic masses: an analysis of 3,090 patients from 212 hospitals

scientific article

Short- and long-term outcomes of endoscopic papillary large balloon dilation with or without sphincterotomy for removal of large bile duct stones.

scientific article published on 28 October 2013

Short-term healing process of artificial ulcers after gastric endoscopic submucosal dissection

scientific article published on 18 August 2011

Short-term prognostic factors for primary sclerosing cholangitis

scientific article published on 31 March 2015

Significance of interferon‐β for the treatment of hepatitis C virus infection in hemodialyzed patients ⬇️

scientific article published on September 1, 2010

Significance of measuring IgG and IgG4 during follow-up of autoimmune pancreatitis

scientific article published on 01 July 2011

Silencing of microRNA-122 enhances interferon-α signaling in the liver through regulating SOCS3 promoter methylation ⬇️

scientific article published on September 6, 2012

Simultaneous Duodenal Metal Stent Placement and EUS-Guided Choledochoduodenostomy for Unresectable Pancreatic Cancer.

scientific article

Simultaneous duodenal stenting and endoscopic ultrasound-guided hepaticogastrostomy using a forward-oblique view echoendoscope

scientific article published on 5 September 2017

Single-balloon versus double-balloon endoscopy for achieving total enteroscopy: a randomized, controlled trial ⬇️

scientific article published on January 26, 2011

Sitafloxacin resistance in Helicobacter pylori isolates and sitafloxacin-based triple therapy as a third-line regimen in Japan.

scientific article published on 7 February 2012

Slight elevation of high-sensitivity C-reactive protein to predict recurrence and survival in patients with early stage hepatitis C-related hepatocellular carcinoma.

scientific article published on 2 September 2014

Slow pull versus suction in endoscopic ultrasound-guided fine-needle aspiration of pancreatic solid masses.

scientific article

Smoking, family history of cancer, and diabetes mellitus are associated with the age of onset of pancreatic cancer in Japanese patients

scientific article published in October 2014

Soluble MICA and a MICA variation as possible prognostic biomarkers for HBV-induced hepatocellular carcinoma

scientific article

Sonographic detection of a patency capsule prior to capsule endoscopy: case report

scientific article published on 19 March 2014

Specific delivery of microRNA93 into HBV-replicating hepatocytes downregulates protein expression of liver cancer susceptible gene MICA.

scientific article

Specific increase in serum autotaxin activity in patients with pancreatic cancer

scientific article published on 31 March 2011

Spiral enteroscopy for therapeutic ERCP in patients with surgically altered anatomy: actual technique and review of the literature

scientific article published on May 2011

Spontaneous clearance of serum hepatitis C virus RNA during the clinical course of hepatocellular carcinoma in patients with chronic hepatitis C.

scientific article published on 7 August 2013

Stiffness of the First Annular Pulley in Normal and Trigger Fingers ⬇️

scientific article published on July 29, 2011

Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer

scientific article published on 9 August 2016

Subserosal injection of hyaluronic acid may prevent perforation after endoscopic resection

scientific article published on October 2009

Successful closure of a large perforation during colorectal endoscopic submucosal dissection by application of polyglycolic acid sheets and fibrin glue

scientific article published on 14 March 2016

Successful endoscopic lithotripsy using a new digital cholangioscope through an overtube placed by an enteroscope

scientific article published on 03 July 2018

Successful guidewire placement across hilar malignant biliary stricture after deceased donor liver transplantation using new digital cholangioscopy

scientific article

Successful treatment of early-stage jejunum adenocarcinoma by endoscopic mucosal resection using double-balloon endoscopy: a case report ⬇️

scientific article published on July 10, 2012

Successful vancomycin desensitization with a combination of rapid and slow infusion methods

scientific article published on 03 April 2006

Superiority of 10-mm-wide balloon over 8-mm-wide balloon in papillary dilation for bile duct stones: A matched cohort study

scientific article

Surveillance of small intestinal abnormalities in patients with hepatocellular carcinoma: a prospective capsule endoscopy study ⬇️

scientific article published on 07 December 2010

Systemic combination therapy of intravenous continuous 5-fluorouracil and subcutaneous pegylated interferon alfa-2a for advanced hepatocellular carcinoma.

scientific article

TGF-β Signaling in Dendritic Cells Governs Colonic Homeostasis by Controlling Epithelial Differentiation and the Luminal Microbiota.

scientific article published on 22 April 2016

TGF-β in inflammatory bowel disease: a key regulator of immune cells, epithelium, and the intestinal microbiota

scientific article

TOKYO criteria 2014 for transpapillary biliary stenting

scientific article published on 04 December 2014

TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis

scientific article published on 4 May 2016

Tacrolimus ameliorates metabolic disturbance and oxidative stress caused by hepatitis C virus core protein: analysis using mouse model and cultured cells

scientific article published on 03 September 2009

Tandem repeats of the 5' flanking region of human have a role as a novel enhancer in gene expression

article

Tandem stent placement as a rescue for stent misplacement in endoscopic ultrasonography-guided hepaticogastrostomy

scientific article published on 25 January 2013

Targeting the complex interactions between microbiota, host epithelial and immune cells in inflammatory bowel disease

scientific article

The ADOPT-LC score: a novel predictive index of in-hospital mortality of cirrhotic patients following surgical procedures, based on a national survey

scientific article published on 7 April 2016

The C-reactive protein/albumin ratio, a novel inflammation-based prognostic score, predicts outcomes in patients with hepatocellular carcinoma

scientific article published on 05 September 2014

The Effectiveness of Liraglutide in Nonalcoholic Fatty Liver Disease Patients with Type 2 Diabetes Mellitus Compared to Sitagliptin and Pioglitazone ⬇️

article by Takamasa Ohki et al published 2012 in The Scientific World Journal

The Effects of Direct Oral Anticoagulants, Warfarin, Aspirin and Thienopyridine on the Performance of Immunochemical, Faecal, Occult Blood Tests

scientific article published on 08 November 2018

The Role of Pancreatic Enzyme Replacement Therapy in Unresectable Pancreatic Cancer: A Prospective Cohort Study

scientific article published on 18 January 2017

The addition of C-reactive protein to validated staging systems improves their prognostic ability in patients with hepatocellular carcinoma

scientific article published on 07 June 2014

The association between arteriosclerosis related diseases and diverticular bleeding

scientific article published on 15 May 2012

The endoscopic ultrasonography-guided rendezvous technique for biliary cannulation: a technical review.

scientific article published on April 2013

The flavonoid apigenin improves glucose tolerance through inhibition of microRNA maturation in miRNA103 transgenic mice.

scientific article published on January 2013

The flavonoid apigenin inhibits hepatitis C virus replication by decreasing mature microRNA122 levels.

scientific article

The impact of direct-acting antivirals on early tumor recurrence after radiofrequency ablation in hepatitis C-related hepatocellular carcinoma

scientific article published on 11 August 2016

The incidence of post-colonoscopy colorectal cancer: a retrospective long-term cohort study using a colonoscopy database

scientific article published on 14 January 2017

The inhibition of renin-angiotensin system in advanced pancreatic cancer: an exploratory analysis in 349 patients

scientific article published on 15 November 2014

The intrahepatic expression levels of bile acid transporters are inversely correlated with the histological progression of nonalcoholic fatty liver disease

scientific article

The prevalence of malignant neoplastic and non-malignant gastrointestinal lesions in cardiology inpatients ⬇️

scientific article published on November 22, 2012

The prevalence of small intestinal polyps in patients with familial adenomatous polyposis: a prospective capsule endoscopy study.

scientific article published in March 2014

The role of microRNAs in hepatocarcinogenesis: current knowledge and future prospects.

scientific article

The utility of balloon enteroscopy in the diagnosis of histiocytic sarcoma of the small intestine: a case report

scientific article published on 21 February 2013

Therapeutic effect of c-Jun N-terminal kinase inhibition on pancreatic cancer.

scientific article published on 24 January 2013

Therapeutic significance of a D-dimer cut-off level of >3 µg/ml in colorectal cancer patients treated with standard chemotherapy plus bevacizumab

scientific article published on 21 May 2010

Thienopyridine derivatives as risk factors for bleeding following high risk endoscopic treatments: Safe Treatment on Antiplatelets (STRAP) study

scientific article published on 15 January 2015

Thrombocytopenia is more severe in patients with advanced chronic hepatitis C than B with the same grade of liver stiffness and splenomegaly

scientific article

Thromboembolisms in Advanced Pancreatic Cancer: A Retrospective Analysis of 475 Patients

scientific article published on 04 August 2017

Timing of capsule endoscopy influences the diagnosis and outcome in obscure-overt gastrointestinal bleeding

scientific article published on 01 May 2012

Tips and troubleshooting for transpapillary metal stenting for distal malignant biliary obstruction

Total cholesterol level for assessing pancreatic insufficiency due to chronic pancreatitis

scientific article

Toward routine use of non-steroidal anti-inflammatory drugs for patients undergoing endoscopic retrograde cholangiopancreatography.

scientific article published on 7 February 2017

Transesophageal Endoscopic Ultrasound-guided Fine Needle Aspiration for the Diagnosis of a Lung Nodule that Was Non-abutting on CT.

scientific article published on 15 September 2017

Transmural biliary drainage can be an alternative to transpapillary drainage in patients with an indwelling duodenal stent

scientific article published on 20 May 2014

Transpapillary versus transmural biliary drainage in patients with an indwelling duodenal stent: when is one indicated over the other?

scientific article published in April 2013

Transparency-enhancing technology allows three-dimensional assessment of gastrointestinal mucosa: A porcine model

scientific article published on 17 January 2018

Treatment outcomes of chemotherapy between unresectable and recurrent biliary tract cancer

scientific article

Trend and risk factors of diverticulosis in Japan: age, gender, and lifestyle/metabolic-related factors may cooperatively affect on the colorectal diverticula formation.

scientific article

Triamcinolone Injection and Shielding with Polyglycolic Acid Sheets and Fibrin Glue for Postoperative Stricture Prevention after Esophageal Endoscopic Resection: A Pilot Study.

scientific article

Trimming a covered metal stent during hepaticogastrostomy by using argon plasma coagulation

scientific article published on 17 September 2013

Tumor markers are more useful in patients undergoing surveillance for hepatocellular carcinoma with unreliable results by ultrasonography

scientific article published on 19 June 2014

Two Cases of Liver Abscesses Derived from Dental Disease in Patients with Alcoholic Chronic Pancreatitis

scientific article published on July 2015

Two cases with hepatic amyloidosis suspected of having primary sclerosing cholangitis.

scientific article published on 15 May 2013

Two-step endoscopic ultrasonography-guided antegrade treatment of a difficult bile duct stone in a surgically altered anatomy patient.

scientific article published on 13 September 2017

Ultrasound evaluation of liver stiffness: accuracy of ultrasound imaging for the prediction of liver cirrhosis as evaluated using a liver stiffness measurement

scientific article published in January 2017

Ultrathin endoscope flexibility can predict discomfort associated with unsedated transnasal esophagogastroduodenoscopy

scientific article published on July 2013

Understanding of HLA-conferred susceptibility to chronic hepatitis B infection requires HLA genotyping-based association analysis

scientific article published on 19 April 2016

Understanding the Mechanical forces of Self-Expandable Metal Stents in the Biliary Ducts

scientific article

Uninodular combined hepatocellular and cholangiocarcinoma with multiple non-neoplastic hypervascular lesions appearing in the liver of a patient with HIV and HCV coinfection.

scientific article published on 19 February 2013

Unique haploinsufficient role of the microRNA-processing molecule Dicer1 in a murine colitis-associated tumorigenesis model.

scientific article

Uridine diphosphate glucuronosyl transferase 1 family polypeptide A1 gene (UGT1A1) polymorphisms are associated with toxicity and efficacy in irinotecan monotherapy for refractory pancreatic cancer.

scientific article

Usefulness of double-balloon enteroscopy for evaluation of duodenal follicular lymphoma ⬇️

scientific article published on April 27, 2012

Usefulness of multi-detector helical CT with multiplanar reconstruction for depicting the duodenal varices with multiple collateral shunt vessels ⬇️

scientific article published on July 24, 2010

Utility of contrast-enhanced ultrasonography with Sonazoid in radiofrequency ablation for hepatocellular carcinoma

scientific article published on 01 April 2011

Utility of single and double balloon endoscopy in patients with difficult colonoscopy: a randomized controlled trial

scientific article published on August 2013

Validation of the Japanese version of the EORTC hepatocellular carcinoma-specific quality of life questionnaire module (QLQ-HCC18)

scientific article

Value of post-vascular phase (Kupffer imaging) by contrast-enhanced ultrasonography using Sonazoid in the detection of hepatocellular carcinoma.

scientific article published on 27 December 2011

Variceal hemorrhage: Analysis of 9987 cases from a Japanese nationwide database

scientific article published on 9 June 2014

Video of the Month: A Novel Endoscopic Full-Thickness Resection for Early Gastric Cancer

scientific article published on 01 November 2015

Visceral adiposity and high adiponectin levels are associated with the prevalence of pancreatic cystic lesions

scientific article published on 17 May 2018

Vonoprazan versus conventional proton pump inhibitor-based triple therapy as first-line treatment against Helicobacter pylori: A multicenter retrospective study in clinical practice.

scientific article published on 17 August 2016

Will there be an HCV meeting in 2020? Summary of the 17th international meeting on hepatitis C virus and related viruses

scientific article published on 24 May 2011

Wire-guided cannulation is not an ideal technique for preventing post-ERCP pancreatitis ⬇️

scientific article published on 01 July 2012

Wire-guided exchange of an inside stent for complex biliary stricture after living donor liver transplantation

scientific article published in May 2016

Withdrawal Times Affects Polyp and Diverticulum Detection on the Right-Side Colon

scientific article published on 01 January 2012

[A Case of Primary Cancer of the Pancreas and Colon Treated with the Combination of Gemcitabine and TS-1].

scientific article published in March 2016

[A case of autoimmune pancreatitis diagnosed at the time of relapse which happened twelve years after the initial onset]

scientific article published on 01 May 2011

[A case of severe necrotizing cellulitis caused by group G Streptococcus dysgalactiae subsp. equisimilis].

scientific article

[Chronic hepatitis C: virologic and immunologic aspects]

scientific article published on 01 July 2004

[Current status and treatment of opportunistic infections associated with HIV infection: discussion]

scientific article published on 01 November 2009

[Diagnosis of bile duct carcinomas].

scientific article

[Discussion Meeting on the perspective of The Japanese Society of Internal Medicine and Japan Surgical Society]

scientific article published on 01 January 2015

[Double infection of HIV and hepatitis viruses]

scientific article published on 01 November 2009

[Endoscopic treatment for rectal cancer].

scientific article published in November 2014

[Hepatocellular carcinoma animal models].

scientific article published in December 2015

[IPMN and pancreatic cyst as high risk of pancreatic cancer]

scientific article published on 01 August 2015

[Leptospirosis with paraplegia and abnormal lung image]

scientific article published on 01 January 2008

[Liver cancer: progress in diagnosis and treatments. Topics: IV. Progress in guideline on liver cancer: 1. Clinical practice guideline for the diagnosis of hepatocellular carcinoma]

scientific article published on 01 January 2014

[Mutations in the hepatitis B virus and treatment of hepatitis]

scientific article published on 01 February 2008

[Mutations of DNA gyrase and topoisomerase IV in clinical isolates of fluoroquinolone-resistant Proteus mirabilis]

scientific article published on 01 February 2006

[Mycobacterium marinum infection causing extensive cutaneous ulcerations and deep abscesses on the extremities: a case report]

scientific article published on 01 April 2010

[Pancreatic tumor:progress in diagnosis and treatment. Topics: II. Intraductal papillary mucinous neoplasm of the pancreas (IPMN) /mucinous cystic neoplasm (MCN); 1. Symptoms and surveillance of IPMN and MCN]

scientific article published on 01 January 2012

[Selection of the high risk population for early detection of pancreas cancer]

scientific article published on 01 January 2018

[The efficacy of safety winged steel needles on needlestick injuries]

scientific article published on 01 January 2006

[Tumor markers for hepatocellular carcinoma]

scientific article published on 01 May 2012

infection and liver diseases: Epidemiology and insights into pathogenesis

miR-425 regulates inflammatory cytokine production in CD4+ T cells via N-Ras upregulation in primary biliary cholangitis

scientific article published on 9 February 2017

p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells

scientific article

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