List of works - Matthias Heinemann

A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology

scientific article

A divide-and-conquer approach to analyze underdetermined biochemical models

scientific article published on 6 January 2009

A flux-sensing mechanism could regulate the switch between respiration and fermentation.

scientific article published on 19 December 2011

An engineered Calvin-Benson-Bassham cycle for carbon dioxide fixation in Methylobacterium extorquens AM1

scientific article published on 04 April 2018

An upper limit on Gibbs energy dissipation governs cellular metabolism

scientific article published on 07 January 2019

Assessment of the interaction between the flux-signaling metabolite fructose-1,6-bisphosphate and the bacterial transcription factors CggR and Cra

scientific article published on 01 August 2018

Autonomous Metabolic Oscillations Robustly Gate the Early and Late Cell Cycle

scientific article published on 10 December 2016

Bacterial persistence from a system-level perspective.

scientific article published on 11 March 2017

Bacterial persistence is an active σS stress response to metabolic flux limitation.

scientific article published on 21 September 2016

Calorie restriction does not elicit a robust extension of replicative lifespan in Saccharomyces cerevisiae

scientific article

Characterization of the AlkS/P(alkB)-expression system as an efficient tool for the production of recombinant proteins in Escherichia coli fed-batch fermentations

scientific article published in February 2007

Condition-dependent cell volume and concentration of Escherichia coli to facilitate data conversion for systems biology modeling

scientific article

Construction and use of a microfluidic dissection platform for long-term imaging of cellular processes in budding yeast

scientific article published on 02 May 2013

Definitions and guidelines for research on antibiotic persistence

scientific article published on 01 July 2019

Differential glucose repression in common yeast strains in response to HXK2 deletion

scientific article published on 22 January 2010

Differential scaling between G1 protein production and cell size dynamics promotes commitment to the cell division cycle in budding yeast

scientific article published on 04 November 2019

Dissecting specific and global transcriptional regulation of bacterial gene expression ⬇️

scientific article published on April 16, 2013

Distinct transcriptional regulation of the two Escherichia coli transhydrogenases PntAB and UdhA.

scientific article published on 2 August 2016

Dynamic single-cell NAD(P)H measurement reveals oscillatory metabolism throughout the E. coli cell division cycle

scientific article published in February 2018

Editorial overview: Systems biology for biotechnology

scientific article published on 19 July 2017

Exploiting cell-free systems: Implementation and debugging of a system of biotransformations.

scientific article published in June 2010

From good old biochemical analyses to high-throughput omics measurements and back

scientific article published on 27 December 2010

Functioning of a metabolic flux sensor in Escherichia coli.

scientific article published on 31 December 2012

Genetics. Getting closer to the whole picture.

scientific article

How bacteria recognise and respond to surface contact

scientific article published on 01 January 2020

Implications of initial physiological conditions for bacterial adaptation to changing environments

scientific article published on 01 September 2020

In silico genome-scale reconstruction and validation of the Staphylococcus aureus metabolic network.

scientific article

Integrated operation of continuous chromatography and biotransformations for the generic high yield production of fine chemicals.

scientific article

Living with an imperfect cell wall: compensation of femAB inactivation in Staphylococcus aureus

scientific article

Mass spectrometric method for analyzing metabolites in yeast with single cell sensitivity

scientific article

Mass spectrometry-based metabolomics of single yeast cells

scientific article

Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices

scientific article published in 2021

Measuring glycolytic flux in single yeast cells with an orthogonal synthetic biosensor

scientific article published on 01 December 2019

Metabolic dynamics during the cell cycle

scientific article published in 2022

Metabolic heterogeneity in clonal microbial populations

scientific article published on 21 February 2018

Metabolic-flux dependent regulation of microbial physiology.

scientific article published on 15 November 2017

Method for quantitative determination of spatial polymer distribution in alginate beads using Raman spectroscopy

scientific article published in March 2005

Multidimensional optimality of microbial metabolism

scientific article published in May 2012

Mutations in respiratory complex I promote antibiotic persistence through alterations in intracellular acidity and protein synthesis

scientific article published on 27 January 2022

New insights in the spatially resolved dynamic pH measurement in macroscopic large absorbent particles by confocal laser scanning microscopy.

scientific article

Nutritional systems biology modeling: from molecular mechanisms to physiology

scientific article

Optimization of a blueprint for in vitro glycolysis by metabolic real-time analysis

scientific article published on 20 March 2011

Optimization of adsorptive immobilization of alcohol dehydrogenases

scientific article published in April 2005

Optimization of enzymatic gas-phase reactions by increasing the long-term stability of the catalyst

scientific article

Perspective: a stirring role for metabolism in cells

scientific article published in 2022

Physiology of mycobacteria

scientific article published on January 2009

Prediction of microbial growth rate versus biomass yield by a metabolic network with kinetic parameters

scientific article

Protein biogenesis machinery is a driver of replicative aging in yeast ⬇️

scientific article

Publisher Correction: Definitions and guidelines for research on antibiotic persistence

scientific article published on 01 July 2019

Putative regulatory sites unraveled by network-embedded thermodynamic analysis of metabolome data

scientific article (publication date: 2006)

Quantitative characterization of the auxin-inducible degron: a guide for dynamic protein depletion in single yeast cells

scientific article published on 5 July 2017

RNA polymerase III limits longevity downstream of TORC1.

scientific article published on 29 November 2017

Reassessing the role of the Escherichia coli CpxAR system in sensing surface contact

scientific article published in PLoS ONE

Reporter metabolite analysis of transcriptional profiles of a Staphylococcus aureus strain with normal phenotype and its isogenic hemB mutant displaying the small-colony-variant phenotype

scientific article

Single cell metabolomics.

scientific article

Suitability of teicoplanin-aglycone bonded stationary phase for simulated moving bed enantioseparation of racemic amino acids employing composition-constrained eluents

scientific article published on 24 February 2006

System-level insights into yeast metabolism by thermodynamic analysis of elementary flux modes

scientific article

Systematic assignment of thermodynamic constraints in metabolic network models

scientific article published on 23 November 2006

Temporal system-level organization of the switch from glycolytic to gluconeogenic operation in yeast

scientific article published on January 2013

The cost of virulence: retarded growth of Salmonella Typhimurium cells expressing type III secretion system 1

scientific article

The quantitative and condition-dependent Escherichia coli proteome

scientific article published on 07 December 2015

Whole lifespan microscopic observation of budding yeast aging through a microfluidic dissection platform

scientific article published on 14 March 2012

anNET: a tool for network-embedded thermodynamic analysis of quantitative metabolome data

scientific article

goes through distinct metabolic phases during its replicative lifespan

scientific article published on 09 April 2019

List of works by Matthias Heinemann

A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology

A divide-and-conquer approach to analyze underdetermined biochemical models

A flux-sensing mechanism could regulate the switch between respiration and fermentation.

An engineered Calvin-Benson-Bassham cycle for carbon dioxide fixation in Methylobacterium extorquens AM1

An upper limit on Gibbs energy dissipation governs cellular metabolism

Assessment of the interaction between the flux-signaling metabolite fructose-1,6-bisphosphate and the bacterial transcription factors CggR and Cra

Autonomous Metabolic Oscillations Robustly Gate the Early and Late Cell Cycle

Bacterial persistence from a system-level perspective.

Bacterial persistence is an active σS stress response to metabolic flux limitation.

Calorie restriction does not elicit a robust extension of replicative lifespan in Saccharomyces cerevisiae

Characterization of the AlkS/P(alkB)-expression system as an efficient tool for the production of recombinant proteins in Escherichia coli fed-batch fermentations

Condition-dependent cell volume and concentration of Escherichia coli to facilitate data conversion for systems biology modeling

Construction and use of a microfluidic dissection platform for long-term imaging of cellular processes in budding yeast

Definitions and guidelines for research on antibiotic persistence

Differential glucose repression in common yeast strains in response to HXK2 deletion

Differential scaling between G1 protein production and cell size dynamics promotes commitment to the cell division cycle in budding yeast

Dissecting specific and global transcriptional regulation of bacterial gene expression ⬇️

Distinct transcriptional regulation of the two Escherichia coli transhydrogenases PntAB and UdhA.

Dynamic single-cell NAD(P)H measurement reveals oscillatory metabolism throughout the E. coli cell division cycle

Editorial overview: Systems biology for biotechnology

Exploiting cell-free systems: Implementation and debugging of a system of biotransformations.

From good old biochemical analyses to high-throughput omics measurements and back

Functioning of a metabolic flux sensor in Escherichia coli.

Genetics. Getting closer to the whole picture.

How bacteria recognise and respond to surface contact

Implications of initial physiological conditions for bacterial adaptation to changing environments

In silico genome-scale reconstruction and validation of the Staphylococcus aureus metabolic network.

Integrated operation of continuous chromatography and biotransformations for the generic high yield production of fine chemicals.

Living with an imperfect cell wall: compensation of femAB inactivation in Staphylococcus aureus

Mass spectrometric method for analyzing metabolites in yeast with single cell sensitivity

Mass spectrometry-based metabolomics of single yeast cells

Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices

Measuring glycolytic flux in single yeast cells with an orthogonal synthetic biosensor

Metabolic dynamics during the cell cycle

Metabolic heterogeneity in clonal microbial populations

Metabolic-flux dependent regulation of microbial physiology.

Method for quantitative determination of spatial polymer distribution in alginate beads using Raman spectroscopy

Multidimensional optimality of microbial metabolism

Mutations in respiratory complex I promote antibiotic persistence through alterations in intracellular acidity and protein synthesis

New insights in the spatially resolved dynamic pH measurement in macroscopic large absorbent particles by confocal laser scanning microscopy.

Nutritional systems biology modeling: from molecular mechanisms to physiology

Optimization of a blueprint for in vitro glycolysis by metabolic real-time analysis

Optimization of adsorptive immobilization of alcohol dehydrogenases

Optimization of enzymatic gas-phase reactions by increasing the long-term stability of the catalyst

Perspective: a stirring role for metabolism in cells

Physiology of mycobacteria

Prediction of microbial growth rate versus biomass yield by a metabolic network with kinetic parameters

Protein biogenesis machinery is a driver of replicative aging in yeast ⬇️

Publisher Correction: Definitions and guidelines for research on antibiotic persistence

Putative regulatory sites unraveled by network-embedded thermodynamic analysis of metabolome data

Quantitative characterization of the auxin-inducible degron: a guide for dynamic protein depletion in single yeast cells

RNA polymerase III limits longevity downstream of TORC1.

Reassessing the role of the Escherichia coli CpxAR system in sensing surface contact

Reporter metabolite analysis of transcriptional profiles of a Staphylococcus aureus strain with normal phenotype and its isogenic hemB mutant displaying the small-colony-variant phenotype

Single cell metabolomics.

Suitability of teicoplanin-aglycone bonded stationary phase for simulated moving bed enantioseparation of racemic amino acids employing composition-constrained eluents

System-level insights into yeast metabolism by thermodynamic analysis of elementary flux modes

Systematic assignment of thermodynamic constraints in metabolic network models

Temporal system-level organization of the switch from glycolytic to gluconeogenic operation in yeast

The cost of virulence: retarded growth of Salmonella Typhimurium cells expressing type III secretion system 1

The quantitative and condition-dependent Escherichia coli proteome

Whole lifespan microscopic observation of budding yeast aging through a microfluidic dissection platform

anNET: a tool for network-embedded thermodynamic analysis of quantitative metabolome data

goes through distinct metabolic phases during its replicative lifespan