List of works by Rino Rappuoli

2. How is the economic assessment of vaccines performed today?

scientific article

3. How comprehensive can we be in the economic assessment of vaccines?

scientific article

3D imaging of the 58 kDa cell binding subunit of the Helicobacter pylori cytotoxin

scientific article published in July 1999

4CMenB Immunization Induces Serum Bactericidal Antibodies Against Non-Serogroup B Meningococcal Strains in Adolescents

scientific article published on 13 November 2020

4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp

scientific article published on 02 October 2020

A 2020 vision for vaccines against HIV, tuberculosis and malaria

scientific article published in May 2011

A C terminus cysteine of diphtheria toxin B chain involved in immunotoxin cell penetration and cytotoxicity

scientific article published on 01 April 1988

A beta-glucan-conjugate vaccine and anti-beta-glucan antibodies are effective against murine vaginal candidiasis as assessed by a novel in vivo imaging technique

scientific article published on 25 December 2009

A common conserved amino acid motif module shared by bacterial and intercellular adhesins: bacterial adherence mimicking cell cell recognition?

scientific article published on February 2001

A crisis of public confidence in vaccines

scientific article

A genetically detoxified derivative of heat-labile Escherichia coli enterotoxin induces neutralizing antibodies against the A subunit

scientific article published on December 1994

A mutant pertussis toxin molecule that lacks ADP-ribosyltransferase activity, PT-9K/129G, is an effective mucosal adjuvant for intranasally delivered proteins

scientific article

A non-living nasal influenza vaccine can induce major humoral and cellular immune responses in humans without the need for adjuvants

scientific article published on 16 March 2005

A novel epigenetic regulator associated with the hypervirulent Neisseria meningitidis clonal complex 41/44.

scientific article

A novel glyco-conjugate vaccine against fungal pathogens

scientific article

A priority-setting aid for new vaccine candidates

scientific article published on March 2014

A recombinant DNA approach to the pertussis vaccine

scientific article published on 01 January 1986

A second pilus type in Streptococcus pneumoniae is prevalent in emerging serotypes and mediates adhesion to host cells

scientific article

A structural overview of the Helicobacter cytotoxin

scientific article

A sweet T cell response

scientific article published on 06 December 2011

A universal vaccine for serogroup B meningococcus

scholarly article

ADITEC: joining forces for next-generation vaccines

scientific article published on April 2012

Acellular pertussis vaccine composed of genetically inactivated pertussis toxin.

scientific article published on January 1995

Acellular pertussis vaccines: a turning point in infant and adolescent vaccination.

scientific article published on January 1996

Adjuvant activity of Mycobacterium bovis BCG expressing CRM197 on the immune response induced by BCG expressing tetanus toxin fragment C.

scientific article published in January 2004

Adjuvant effect of non-toxic mutants of E. coli heat-labile enterotoxin following intranasal, oral and intravaginal immunization

scientific article published on 01 January 1998

Adjuvant is necessary for a robust immune response to a single dose of H1N1 pandemic flu vaccine in mice.

scientific article

Adjuvanted H5N1 vaccine induces early CD4+ T cell response that predicts long-term persistence of protective antibody levels

scholarly article

Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88

scientific article

Adjuvanting a subunit COVID-19 vaccine to induce protective immunity

scientific article published on 19 April 2021

Aflunov®: a vaccine tailored for pre-pandemic and pandemic approaches against influenza

scientific article

Ageing and immunity: addressing immune senescence to ensure healthy ageing

scientific article published on 01 April 2010

Alum adjuvanticity: unraveling a century old mystery

scientific article published on 01 August 2008

An MF59-adjuvanted inactivated influenza vaccine containing A/Panama/1999 (H3N2) induced broader serological protection against heterovariant influenza virus strain A/Fujian/2002 than a subunit and a split influenza vaccine

scientific article published on 19 January 2006

An analysis of the sequence variability of meningococcal fHbp, NadA and NHBA over a 50-year period in the Netherlands

scientific article

An anti-repression Fur operator upstream of the promoter is required for iron-mediated transcriptional autoregulation in Helicobacter pylori

scientific article published in November 2003

An audience with... Rino Rappuoli

scientific article

An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus

scientific article published on 11 July 2004

An unwanted guest: Neisseria meningitidis - carriage, risk for invasive disease and the impact of vaccination with insight on Italy incidence

scientific article published on 19 May 2017

Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin

scientific article

Anatomy of Omicron BA.1 and BA.2 neutralizing antibodies in COVID-19 mRNA vaccinees

scientific article published on 13 June 2022

Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2.

scientific article

Antibody to genome-derived neisserial antigen 2132, a Neisseria meningitidis candidate vaccine, confers protection against bacteremia in the absence of complement-mediated bactericidal activity

scientific article published on 19 November 2003

Antibody-dependent macrophage-mediated activity against Helicobacter pylori in the absence of complement

scientific article published on October 2002

Anticipating crisis: towards a pandemic flu vaccination strategy through alignment of public health and industrial policy

scientific article

Antigenic recognition of pertussis and cholera toxin by the same antipeptide antibodies

scientific article published on 01 January 1986

Antimicrobial resistance and the role of vaccines

article published in the Proceedings of the National Academy of Sciences of the United States of America

Application of microbial genomic science to advanced therapeutics

scientific article

Are serological responses to acellular pertussis antigens sufficient criteria to ensure that new combination vaccines are effective for prevention of disease?

scientific article published on January 1, 1997

Auto ADP-ribosylation of NarE, a Neisseria meningitidis ADP-ribosyltransferase, regulates its catalytic activities

scientific article published on 20 August 2013

Auto-Assembling Detoxified Staphylococcus aureus Alpha-Hemolysin Mimicking the Wild-Type Cytolytic Toxin

scientific article published on 30 March 2016

Autoregulation of Helicobacter pylori Fur revealed by functional analysis of the iron-binding site

scientific article published on 01 November 2002

Bacterial pathogen genomics and vaccines.

scientific article

Beta-glucan-CRM197 conjugates as candidates antifungal vaccines

scientific article

Beyond cost-effectiveness: Using systems analysis for infectious disease preparedness

scientific article (publication date: December 2016)

Big science for vaccine development

article

Biochemical and biological characteristics of cross-reacting material 197 CRM197, a non-toxic mutant of diphtheria toxin: use as a conjugation protein in vaccines and other potential clinical applications

scientific article published on 28 June 2011

Biotechnology and vaccines: application of functional genomics to Neisseria meningitidis and other bacterial pathogens

scientific article published in September 2004

Blocking bacterial enterotoxins

scientific article published on 01 March 2000

Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes

scientific article

Bridging the gap: need for a data repository to support vaccine prioritization efforts

scientific article

Bridging the knowledge gaps in vaccine design

scientific article published on December 2007

Bringing influenza vaccines into the 21st century.

scientific article

Building an insurance against modern pandemics.

scientific article

Cell penetration of diphtheria toxin. Reduction of the interchain disulfide bridge is the rate-limiting step of translocation in the cytosol

scientific article published on 01 January 1993

Cellular microbiology emerging

scientific article published on January 1996

Cellular pertussis vaccine containing a Bordetella pertussis strain that produces a nontoxic pertussis toxin molecule

scientific article published on March 1992

Changing Priorities in Vaccinology: Antibiotic Resistance Moving to the Top.

scientific article published on 30 May 2018

Changing route: aerosol vaccine against tuberculosis

scientific article published on 20 August 2014

Characterization and immunogenicity of the CagF protein of the cag pathogenicity island of Helicobacter pylori

scientific article published on November 2002

Characterization of an IS-like element from Mycobacterium tuberculosis

scientific article

Characterization of diverse subvariants of the meningococcal factor H (fH) binding protein for their ability to bind fH, to mediate serum resistance, and to induce bactericidal antibodies

scientific article

Characterization of the HspR-mediated stress response in Helicobacter pylori

scientific article published on June 2002

Characterization of the antibody response to pneumococcal glycoconjugates and the effect of heat-labile enterotoxin on IGg subclasses after intranasal immunization

scientific article published on 16 April 2001

Chemistry of a new investigational quadrivalent meningococcal conjugate vaccine that is immunogenic at all ages

scientific article published on 18 July 2009

Chlamydia trachomatis control requires a vaccine

scientific article

Clonal success of piliated penicillin nonsusceptible pneumococci ⬇️

scholarly article

Cloning of a novel pilin-like gene from Bordetella pertussis: homology to the fim2 gene

scientific article

Combination adjuvants for the induction of potent, long-lasting antibody and T-cell responses to influenza vaccine in mice.

scientific article

Combined adenovirus vector and hepatitis C virus envelope protein prime-boost regimen elicits T cell and neutralizing antibody immune responses

scientific article

Combined conjugate vaccines: enhanced immunogenicity with the N19 polyepitope as a carrier protein

scientific article

Common features of the NAD-binding and catalytic site of ADP-ribosylating toxins.

scientific article published in October 1994

Comparative Systems Analyses Reveal Molecular Signatures of Clinically tested Vaccine Adjuvants

scientific article published on 13 December 2016

Comparative genomics of Neisseria meningitidis: core genome, islands of horizontal transfer and pathogen-specific genes

article

Comparative immunogenicity and efficacy of equivalent outer membrane vesicle and glycoconjugate vaccines against nontyphoidal

article published in the Proceedings of the National Academy of Sciences of the United States of America

Compare voting systems to improve them

scientific article published in January 2017

Comparison of Open-Source Reverse Vaccinology Programs for Bacterial Vaccine Antigen Discovery

scholarly article by Mattia Dalsass et al published 14 February 2019 in Frontiers in Immunology

Complete Genome Sequence of Neisseria meningitidis Serogroup B Strain MC58

scientific article

Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae

scientific article

Conformational changes in diphtheria toxoids. Analysis with monoclonal antibodies

scientific article published on 01 June 1987

Conjugates and reverse vaccinology to eliminate bacterial meningitis

scientific article

Conservation of meningococcal antigens in the genus Neisseria

scientific article published on 11 June 2013

Construction of nontoxic derivatives of cholera toxin and characterization of the immunological response against the A subunit.

scientific article

Core values for vaccine evaluation

scientific article published on 22 December 2016

Correction: Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species.

scientific article published on 20 October 2011

Correlates of adjuvanticity: A review on adjuvants in licensed vaccines

article

Correlates of protection against influenza infection in humans--on the path to a universal vaccine?

scientific article

Corrigendum: Vaccines Against Antimicrobial Resistance

scientific article published on 21 July 2020

Cost effectiveness has its place, but so does common sense

scientific article published on 13 November 2014

Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients

scholarly article

CrgA is an inducible LysR-type regulator of Neisseria meningitidis, acting both as a repressor and as an activator of gene transcription

scientific article

Current Developments in New Vaccines for Adolescents ⬇️

scientific article published on June 1, 1997

Current approaches to developing a preventative HIV vaccine.

scientific article

Cytoskeletal alterations as a parameter for assessment of toxicity

scientific article published on 01 June 1988

DNA binding of the Bordetella pertussis H1 homolog alters in vitro DNA flexibility

scientific article published on May 1996

DNA element of Corynebacterium diphtheriae with properties of an insertion sequence and usefulness for epidemiological studies

scientific article

DNA topology affects transcriptional regulation of the pertussis toxin gene of Bordetella pertussis in Escherichia coli and in vitro

scientific article published on August 1993

DNA vaccination

scientific article published in August 2003

Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen

scientific article

Deletion of the major proteolytic site of the Helicobacter pylori cytotoxin does not influence toxin activity but favors assembly of the toxin into hexameric structures.

scientific article published on November 1998

Deploy vaccines to fight superbugs

scientific article published in December 2017

Designing the next generation of vaccines for global public health

scientific article published on 17 June 2011

Designing vaccines for the twenty-first century society

scientific article

Detection and physical map of a omega tox+-related defective prophage in Corynebacterium diphtheriae Belfanti 1030(-)tox-.

scientific article

Detection of a vacuolating cytotoxin in stools from children with diarrhea

scientific article published on July 1996

Detoxification of the Helicobacter pylori cytotoxin

scientific article

Developing vaccines for an aging population

scientific article published on April 2015

Development and clinical testing of an acellular pertussis vaccine containing genetically detoxified pertussis toxin

scientific article published on February 1, 1992

Development of V2-deleted trimeric envelope vaccine candidates from human immunodeficiency virus type 1 (HIV-1) subtypes B and C.

scientific article published on 20 September 2005

Development of a glycoconjugate vaccine to prevent meningitis in Africa caused by meningococcal serogroup X.

scientific article

Development of a mouse model of Helicobacter pylori infection that mimics human disease

scientific article

Development of a vaccine against serogroup B has been the main scientific challenge. Preface

scientific article published in May 2012

Development of an influenza virus protein array using Sortagging technology

scientific article published on 25 May 2012

Development of the new acellular recombinant pertussis vaccine

scientific article published on 01 July 1994

Development of vaccines against Helicobacter pylori

scientific article published on August 2009

Did the inheritance of a pathogenicity island modify the virulence of Helicobacter pylori?

scientific article published on May 1997

Different human vaccine adjuvants promote distinct antigen-independent immunological signatures tailored to different pathogens

scientific article published on 21 January 2016

Differential binding of BvgA to two classes of virulence genes of Bordetella pertussis directs promoter selectivity by RNA polymerase.

scientific article

Differential response of the bvg virulence regulon of Bordetella pertussis to MgSO4 modulation

scientific article

Diphtheria toxin and its mutant crm 197 differ in their interaction with lipids

scientific article

Dissecting human T cell responses against Bordetella species

scientific article published on October 1988

Distribution and genetic variability of three vaccine components in a panel of strains representative of the diversity of serogroup B meningococcus

scientific article

Dual RNA-seq of Nontypeable Haemophilus influenzae and Host Cell Transcriptomes Reveals Novel Insights into Host-Pathogen Cross Talk

scientific article

Dual control of Helicobacter pylori heat shock gene transcription by HspR and HrcA.

scientific article published on May 2004

Editorial overview: Preventive and therapeutic vaccines: Vaccination against viral disease - current advances and challenges

scientific article published in April 2017

Editorial overview: Vaccines 2020

scientific article published on 01 August 2020

Editorial overview: Vaccines: novel technologies for vaccine development

scientific article published on 04 August 2016

Editorial: A Global Perspective on Vaccines: Priorities, Challenges and Online Information.

scientific article published on 12 November 2019

Editorial: Advanced Immunization Technologies for Next Generation Vaccines

scientific article published on 06 May 2020

Editorial: Reverse Vaccinology

scientific article published on 03 December 2019

Effect of Neisseria meningitidis fur mutations on global control of gene transcription

scientific article published in April 2006

Effect of heparin binding on Helicobacter pylori resistance to serum

scientific article published in January 2004

Effects of the insertion of a nonapeptide from murine IL-1beta on the immunogenicity of carrier proteins delivered by live attenuated Salmonella

scientific article

Efficacy of vaccination with different combinations of MF59-adjuvanted and nonadjuvanted seasonal and pandemic influenza vaccines against pandemic H1N1 (2009) influenza virus infection in ferrets

scientific article

Efficacy, immunogenicity, and safety of a parenteral vaccine against Helicobacter pylori in healthy volunteers challenged with a Cag-positive strain: a randomised, placebo-controlled phase 1/2 study

scientific article published on 02 July 2018

Efficient production of heat-labile enterotoxin mutant proteins by overexpression of dsbA in a degP-deficient Escherichia coli strain.

scientific article

Emerging experience with meningococcal serogroup B protein vaccines

scientific article

Emerging infectious diseases: A proactive approach

scientific article (publication date: 10 April 2017)

Emerging vaccine informatics

scientific article

Enhancement of protective efficacy following intranasal immunization with vaccine plus a nontoxic LTK63 mutant delivered with nanoparticles

scientific article

Environmental regulation of virulence factors in Bordetella species

scientific article

Epitope mapping of a bactericidal monoclonal antibody against the factor H binding protein of Neisseria meningitidis.

scientific article

Erratum for Baddal et al., Dual RNA-seq of Nontypeable Haemophilus influenzae and Host Cell Transcriptomes Reveals Novel Insights into Host-Pathogen Cross Talk

scientific article published on 12 April 2016

Escherichia coli heat-labile enterotoxin promotes protective Th17 responses against infection by driving innate IL-1 and IL-23 production.

scientific article

Escherichia coli: great diversity around a common core

scientific article published on 5 June 2012

European Commission COST/STD Initiative. Report of the expert panel VIII. New vaccines, especially new combined vaccines

scientific article published on May 1996

Evaluation of a Group A Streptococcus synthetic oligosaccharide as vaccine candidate

scientific article published on 24 September 2010

Evaluation of the recombinant 38-kilodalton antigen of Mycobacterium tuberculosis as a potential immunodiagnostic reagent

scientific article published on March 1997

Evolution of functional polymorphism in the gene coding for the Helicobacter pylori cytotoxin

scientific article published in January 2002

Experimental model of Helicobacter pylori infection

scientific article

Expression and immunological properties of the five subunits of pertussis toxin

scientific article

Expression and selective up-regulation of toxin-related mono ADP-ribosyltransferases by pathogen-associated molecular patterns in alveolar epithelial cells

scientific article published on 3 August 2007

Expression of factor H binding protein in meningococcal strains can vary at least 15-fold and is genetically determined

scientific article published on 17 February 2016

Expression of fragment C of tetanus toxin fused to a carboxyl-terminal fragment of diphtheria toxin in Salmonella typhi CVD 908 vaccine strain

scientific article published on November 1995

Factor H-binding protein, a unique meningococcal vaccine antigen

scientific article published in December 2008

Families of bacterial signal-transducing proteins

scientific article

FdeC, a Novel Broadly Conserved Escherichia coli Adhesin Eliciting Protection against Urinary Tract Infections

scientific article

Finding epitopes with computers

scientific article published in October 2013

Formaldehyde treatment of proteins can constrain presentation to T cells by limiting antigen processing

scientific article published on May 1994

Four-component Meningococcal Serogroup B Vaccine Induces Antibodies With Bactericidal Activity Against Diverse Outbreak Strains in Adolescents

scientific article published on 13 October 2020

From Pasteur to genomics: progress and challenges in infectious diseases.

scientific article published in November 2004

From empiricism to rational design: a personal perspective of the evolution of vaccine development

scientific article

From pioneers to marketeers

scientific article published in Nature

Functional analysis of the Helicobacter pylori principal sigma subunit of RNA polymerase reveals that the spacer region is important for efficient transcription

scientific article published in October 1998

Functional analysis of the pertussis toxin promoter

scientific article published on September 1, 1992

Fur functions as an activator and as a repressor of putative virulence genes in Neisseria meningitidis

scientific article

Further analysis of the sequence of the S1 subunit of pertussis toxin

scientific article published on March 1991

Future Challenges for Vaccinologists

scientific article

GITR contributes to the systemic adjuvanticity of the Escherichia coli heat-labile enterotoxin.

scientific article

GNA33 from Neisseria meningitidis serogroup B encodes a membrane-bound lytic transglycosylase (MltA).

scientific article published in August 2002

GNA33 of Neisseria meningitidis is a lipoprotein required for cell separation, membrane architecture, and virulence.

scientific article

Generating memory with vaccination

scientific article published on August 2009

Generation of human monoclonal antibodies that confer protection against pertussis toxin ⬇️

scientific article published on March 1, 1992

Genetic Meningococcal Antigen Typing System (gMATS): A genotyping tool that predicts 4CMenB strain coverage worldwide

scientific article published on 17 January 2019

Genetic detoxification of bacterial toxins

scientific article published on January 2003

Genetic detoxification of bacterial toxins: a new approach to vaccine development

scientific article

Genetically derived toxoids for use as vaccines and adjuvants

scientific article

Genetically detoxified pertussis toxin induces Th1/Th17 immune response through MAPKs and IL-10-dependent mechanisms.

scientific article

Genetics of pertussis toxin

scientific article published on January 1989

Genome Analysis Reveals Pili in Group B Streptococcus

scientific article published in Science

Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial "pan-genome"

scientific article

Genome and infectious diseases

scientific article published in May 2005

Genome sequencing of disease and carriage isolates of nontypeable Haemophilus influenzae identifies discrete population structure

scientific article published on 25 March 2014

Genome-based vaccine development: a short cut for the future

scientific article published on January 2009

Genome-derived vaccines

scientific article published on February 2004

Genome‑based vaccine development: A short cut for the future ⬇️

scientific article published on May 1, 2008

Genomics of ecology and industrial microbiology

scientific article

Glycoconjugate vaccines: Principles and mechanisms

scientific article published on 01 August 2018

Group B Streptococcus crosses human epithelial cells by a paracellular route

scientific article published on 9 December 2005

Group B Streptococcus: global incidence and vaccine development

scientific article published on 6 November 2006

Growth of Helicobacter pylori in media containing cyclodextrins

scientific article

Growth phase-dependent regulation of target gene promoters for binding of the essential orphan response regulator HP1043 of Helicobacter pylori

scientific article published on September 2002

H1N1: can a pandemic cycle be broken?

scientific article

HIV-1 tat promotes integrin-mediated HIV transmission to dendritic cells by binding Env spikes and competes neutralization by anti-HIV antibodies

scientific article

HadA is an atypical new multifunctional trimeric coiled-coil adhesin of Haemophilus influenzae biogroup aegyptius, which promotes entry into host cells

scientific article published on 12 March 2009

Heat-labile enterotoxin of Escherichia coli and its site-directed mutant LTK63 enhance the proliferative and cytotoxic T-cell responses to intranasally co-immunized synthetic peptides

scientific article published on April 1999

Helicobacter pylori CagA: From Pathogenic Mechanisms to Its Use as an Anti-Cancer Vaccine

scientific article published on 15 October 2013

Helicobacter pylori VacA cytotoxin associated with the bacteria increases epithelial permeability independently of its vacuolating activity

scientific article published on August 1999

Helicobacter pylori cytotoxin-associated gene A (CagA) subverts the apoptosis-stimulating protein of p53 (ASPP2) tumor suppressor pathway of the host

scientific article

Helicobacter pylori cytotoxin: importance of native conformation for induction of neutralizing antibodies

scientific article

Helicobacter pylori induced interleukin-8 expression in gastric epithelial cells is associated with CagA positive phenotype

scientific article published on January 1995

Helicobacter pylori infection negatively influences pregnancy outcome in a mouse model

scientific article

Helicobacter pylori interactions with host serum and extracellular matrix proteins: potential role in the infectious process

scientific article

Helicobacter pylori neutrophil-activating protein stimulates tissue factor and plasminogen activator inhibitor-2 production by human blood mononuclear cells

scientific article published on 23 February 2001

Helicobacter pylori virulence and genetic geography ⬇️

scientific article

Helicobacter pylori-specific CD4+ T-cell clones from peripheral blood and gastric biopsies

scientific article

Helicobacter pylori: after the genomes, back to biology

scientific article published on 31 March 2003

Helicobacter pylori: molecular evolution of a bacterial quasi-species

scientific article

Hemagglutination inhibition antibody titers as a correlate of protection for inactivated influenza vaccines in children

scientific article published in December 2011

Histidine 21 is at the NAD+ binding site of diphtheria toxin

scientific article published in July 1989

Human T cell clones define S1 subunit as the most immunogenic moiety of pertussis toxin and determine its epitope map.

scientific article published on May 1989

Human T cell immunity against Bordetella pertussis analyzed at clonal level

scientific article published on January 1, 1991

Human T lymphocyte clones specific for "Bordetella pertussis"

scientific article published on 01 January 1986

Human T-cell immunity against Bordetella pertussis analyzed at clonal level.

scientific article published in January 1988

Human circulating influenza-CD4+ ICOS1+IL-21+ T cells expand after vaccination, exert helper function, and predict antibody responses

scientific article published on 12 August 2013

Human heat shock protein (Hsp) 90 interferes with Neisseria meningitidis adhesin A (NadA)-mediated adhesion and invasion

scientific article published on 8 December 2011

Human monoclonal antibodies for discovery, therapy, and vaccine acceleration

scientific article published on 23 August 2019

Human papillomavirus E2 protein: a potential key regulator of viral cell pathogenesis

scientific article published on July 2012

Hydrophobic photolabelling of pertussis toxin subunits interacting with lipids

scientific article published in January 1986

IL-1 stimulates a diverging signaling pathway in EL4 6.1 thymoma cells. IL-2 release, but not IL-2 receptor expression, is sensitive to pertussis toxin ⬇️

scientific article published on July 1, 1995

INNAMORA, a European Workshop focussed on the mechanisms of innate immunity in pathogen-host interaction and their exploitation in novel mucosal immunisation strategies

scientific article published on 01 June 2003

Identification of Neisseria meningitidis nonlipopolysaccharide ligands for class A macrophage scavenger receptor by using a novel assay

scientific article published on September 2006

Identification of a 35-Kilodalton Protein Containing B- and T-Cell Epitopes

scientific article published in 2006

Identification of a 35-kilodalton Mycobacterium tuberculosis protein containing B- and T-cell epitopes

scientific article

Identification of a new OmpA-like protein in Neisseria gonorrhoeae involved in the binding to human epithelial cells and in vivo colonization

scientific article published on June 2007

Identification of a universal Group B streptococcus vaccine by multiple genome screen

scientific article

Identification of an iron-sulfur cluster that modulates the enzymatic activity in NarE, a Neisseria meningitidis ADP-ribosyltransferase

scientific article published on 10 September 2009

Identification of iron-activated and -repressed Fur-dependent genes by transcriptome analysis of Neisseria meningitidis group B.

scientific article

Identification of neutralizing human monoclonal antibodies from Italian Covid-19 convalescent patients

scientific article published on 09 May 2020

Identification of protective and broadly conserved vaccine antigens from the genome of extraintestinal pathogenic Escherichia coli

scientific article

Identification of subregions of Bordetella pertussis filamentous hemagglutinin that stimulate human T-cell responses ⬇️

scientific article published on September 1, 1991

IgA-dependent cell-mediated activity against enteropathogenic bacteria: distribution, specificity, and characterization of the effector cells

scientific article published in August 1984

Immune response to SARS-CoV-2 Omicron variant in patients and vaccinees following homologous and heterologous vaccinations

scientific article published in 2022

Immunisation against meningococcus B

Immunization with the Chlamydia trachomatis major outer membrane protein, using adjuvants developed for human vaccines, can induce partial protection in a mouse model against a genital challenge

scientific article published on 06 September 2005

Immunobiology of Helicobacter pylori infection ⬇️

scientific article published on August 1, 1997

Immunohistochemical study of lymphocyte populations infiltrating the gastric mucosa of beagle dogs experimentally infected with Helicobacter pylori

scientific article published on August 2000

Immunological fingerprint of 4CMenB recombinant antigens via protein microarray reveals key immunosignatures correlating with bactericidal activity

scientific article published on 05 October 2020

Improving accountability in vaccine decision-making

scientific article

Improving influenza vaccines

scientific article published on 01 August 2012

In silico identification of novel bacterial ADP-ribosyltransferases

scientific article published on April 2004

In vitro analysis of protein-operator interactions of the NikR and fur metal-responsive regulators of coregulated genes in Helicobacter pylori

scientific article

In vitro selection of high affinity HspR-binding sites within the genome of Helicobacter pylori

scientific article published on 01 January 2002

In vivo dissection of the Helicobacter pylori Fur regulatory circuit by genome-wide location analysis

scientific article published on July 2006

Inactivated and adjuvanted influenza vaccines.

scientific article

Induction of antigen-specific antibodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant

scientific article

Induction of interleukin-8 secretion from gastric epithelial cells by a cagA negative isogenic mutant of Helicobacter pylori

scientific article published on October 1995

Induction of neutralizing antibodies against diphtheria toxin by priming with recombinant Mycobacterium bovis BCG expressing CRM(197), a mutant diphtheria toxin.

scientific article published on February 2001

Induction of protective serum meningococcal bactericidal and diphtheria-neutralizing antibodies and mucosal immunoglobulin A in volunteers by nasal insufflations of the Neisseria meningitidis serogroup C polysaccharide-CRM197 conjugate vaccine mixed

scientific article

Influence of Statins on Influenza Vaccine Response in Elderly Individuals

scientific article published on 28 October 2015

Influence of sequence variability on bactericidal activity sera induced by Factor H binding protein variant 1.1.

scientific article published on 03 December 2010

Influence of serogroup B meningococcal vaccine antigens on growth and survival of the meningococcus in vitro and in ex vivo and in vivo models of infection

scientific article published on 10 January 2010

Influenza vaccine immunology

scientific article

Influenza: options to improve pandemic preparation

scientific article

Inhibiting neuraminidase can make the difference

scientific article published on 25 January 2019

Innate imprinting by the modified heat-labile toxin of Escherichia coli (LTK63) provides generic protection against lung infectious disease

scientific article published in December 2004

Inner Workings: 1885, the first rabies vaccination in humans

scientific article

Inside sensors detecting outside pathogens

scientific article published on 01 November 2004

Interaction of the pertussis toxin peptide containing residues 30-42 with DR1 and the T-cell receptors of 12 human T-cell clones ⬇️

scientific article published on April 1, 1992

Interlaboratory standardization of the sandwich enzyme-linked immunosorbent assay designed for MATS, a rapid, reproducible method for estimating the strain coverage of investigational vaccines

scientific article

Intranasal immunization with SAG1 and nontoxic mutant heat-labile enterotoxins protects mice against Toxoplasma gondii

scientific article

Intranasal immunization with genetically detoxified diphtheria toxin induces T cell responses in humans: enhancement of Th2 responses and toxin-neutralizing antibodies by formulation with chitosan

scientific article published in February 2004

Introduction of unmarked mutations in the Helicobacter pylori vacA gene with a sucrose sensitivity marker

scientific article

Introduction to the supplement

scientific article

Introduction to the vaccine supplement

scientific article published on 22 December 2016

Introduction: Addressing the challenge of group B streptococcal disease

scientific article published on 01 August 2013

Invariant NKT cells sustain specific B cell responses and memory

scientific article

Investigation on the effect of immune selection on resistance to bactericidal antibodies to group B meningococci in vitro

scientific article published on 26 August 2009

Involvement of the intrinsic and extrinsic cell-death pathways in the induction of apoptosis of mature lymphocytes by the Escherichia coli heat-labile enterotoxin

scientific article published on 01 February 2009

Isogenic mutants of the cag pathogenicity island of Helicobacter pylori in the mouse model of infection: effects on colonization efficiency

scientific article published on 01 May 2002

Italy must invest more in science and technology

scientific article published on 01 April 2008

LTK63 and LTR72, two mucosal adjuvants ready for clinical trials

scientific article

Lack of interference with immunogenicity of a chimeric alphavirus replicon particle-based influenza vaccine by preexisting antivector immunity

scientific article

Learning from the 2009 H1N1 pandemic: prospects for more broadly effective influenza vaccines

scientific article

Lessons from Reverse Vaccinology for viral vaccine design

scientific article published on 29 March 2015

Living dangerously: how Helicobacter pylori survives in the human stomach

scientific article

Long noncoding RNAs are involved in multiple immunological pathways in response to vaccination

scientific article published on 09 August 2019

Long-term solutions for the problem of vaccine shortages

Lymphokine secretion and cytotoxic activity of human CD4+ T-cell clones against Bordetella pertussis ⬇️

scientific article published on October 1, 1991

LytM proteins play a crucial role in cell separation, outer membrane composition, and pathogenesis in nontypeable Haemophilus influenzae.

scientific article

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Variability of genes encoding surface proteins used as vaccine antigens in meningococcal endemic and epidemic strain panels from Norway

scientific article published on 12 March 2014

Vir90, a virulence-activated gene coding for a Bordetella pertussis iron-regulated outer membrane protein

scientific article published on July 2003

Vision for a systems architecture to integrate and transform population health

article published in the Proceedings of the National Academy of Sciences of the United States of America

Visualizing bacterial surfaces in real time

scientific article published on March 2009

What are affordable vaccines?

scientific article published on 01 March 2015

Will Systems Biology Deliver Its Promise and Contribute to the Development of New or Improved Vaccines? Systems Biology Views of Vaccine Innate and Adaptive Immunity

scientific article published on 16 October 2017

c-Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs

scientific article

cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors

scientific article published on December 1996

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