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List of works by Mary Jeanne Kreek

"Binge" cocaine differentially alters preproenkephalin mRNA levels in guinea pig brain

scientific article

"Effects of the novel relatively short-acting kappa opioid receptor antagonist LY2444296 in behaviors observed after chronic extended-access cocaine self-administration in rats".

scientific article

1-year retention and social function after buprenorphine-assisted relapse prevention treatment for heroin dependence in Sweden: a randomised, placebo-controlled trial

scientific article published in February 2003

A 3' UTR SNP rs885863, a cis-eQTL for the circadian gene VIPR2 and lincRNA 689, is associated with opioid addiction

scientific article published on 05 November 2019

A C17T polymorphism in the mu opiate receptor is associated with quantitative measures of drug use in African American women ⬇️

scientific article published on November 11, 2010

A functional haplotype implicated in vulnerability to develop cocaine dependence is associated with reduced PDYN expression in human brain

scientific article published on 15 October 2008

A non-coding CRHR2 SNP rs255105, a cis-eQTL for a downstream lincRNA AC005154.6, is associated with heroin addiction.

scientific article published on 28 June 2018

A window of opportunity: maximizing the effectiveness of new HCV regimens in the United States with the expansion of the Affordable Care Act.

scientific article published on 20 January 2015

ABCB1 (MDR1) genetic variants are associated with methadone doses required for effective treatment of heroin dependence

scientific article published on 17 April 2008

Acute ‘binge’ cocaine administration elevates dynorphin mRNA in the caudate putamen of C57BL/6J but not 129/J mice ⬇️

scientific article published on June 6, 2003

Adolescent and young adult heroin patients: drug use and success in methadone maintenance treatment

scientific article published in January 2006

Adolescent oxycodone self administration alters subsequent oxycodone-induced conditioned place preference and anti-nociceptive effect in C57BL/6J mice in adulthood

scientific article published on 7 September 2016

African-specific variability in the acetylcholine muscarinic receptor M4: association with cocaine and heroin addiction

scientific article published on 07 June 2016

Alcohol: a stimulant activating brain stress responsive systems with persistent neuroadaptation

scientific article

Alterations in hypothalamic-pituitary-adrenal axis activity and in levels of proopiomelanocortin and corticotropin-releasing hormone-receptor 1 mRNAs in the pituitary and hypothalamus of the rat during chronic 'binge' cocaine and withdrawal

scientific article

Alterations of expression of inflammation/immune-related genes in the dorsal and ventral striatum of adult C57BL/6J mice following chronic oxycodone self-administration: a RNA sequencing study

scientific article published on 26 June 2017

Altered levels of basal cortisol in healthy subjects with a 118G allele in exon 1 of the Mu opioid receptor gene

scientific article published on 21 June 2006

Antiallodynic effects of loperamide and fentanyl against topical capsaicin-induced allodynia in unanesthetized primates

scientific article

Antidepressant treatment patterns in a novel methadone maintenance clinic targeting young adults an observational study

scientific article published on January 2006

Are trait impulsivity and exposure to cannabis or alcohol associated with the age of trajectory of cocaine use? A gender-specific dimensional analysis in humans with cocaine dependence diagnosis

scientific article published on 19 August 2019

Association analysis of polymorphisms in serotonin 1B receptor (HTR1B) gene with heroin addiction: a comparison of molecular and statistically estimated haplotypes

scientific article published in January 2006

Association of Genetic Variation in Pharmacodynamic Factors with Methadone Dose Required for Effective Treatment of Opioid Addiction ⬇️

scientific article published on May 1, 2013

Association of Polymorphisms of the Mu Opioid Receptor Gene with the Severity of HIV Infection and Response to HIV Treatment ⬇️

scientific article published on March 28, 2012

Association of Variants of Arginine Vasopressin and Arginine Vasopressin Receptor 1A With Severe Acetaminophen Liver Injury

scientific article

Association of polymorphisms in the melanocortin receptor type 2 (MC2R, ACTH receptor) gene with heroin addiction

scientific article published on 26 February 2008

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts

scientific article

Association of variants of prodynorphin promoter 68-bp repeats in caucasians with opioid dependence diagnosis: Effect on age trajectory of heroin use

scientific article published on 29 March 2019

Associations of cardiovascular variables and HAART with cognition in middle-aged HIV-infected and uninfected women ⬇️

scientific article published on October 18, 2011

Behavioral Effects and Central Nervous System Levels of the Broadly Available κ-Agonist Hallucinogen Salvinorin A Are Affected by P-Glycoprotein Modulation In Vivo ⬇️

scientific article published on March 20, 2012

Behavioral and neurochemical changes induced by oxycodone differ between adolescent and adult mice

scientific article published on 10 September 2008

Biological clock: biological clocks may modulate drug addiction

scientific article published in October 2005

Blockade of alcohol escalation and "relapse" drinking by pharmacological FAAH inhibition in male and female C57BL/6J mice

scientific article published on 20 July 2017

Bruce S. McEwen, Ph.D.

scientific article published on 10 March 2020

CYP2B6SNPs are associated with methadone dose required for effective treatment of opioid addiction ⬇️

scientific article published on July 25, 2011

Can a rapid measure of self-exposure to drugs of abuse provide dimensional information on depression comorbidity?

scientific article

Carbon dioxide-induced anesthesia results in a rapid increase in plasma levels of vasopressin

scientific article published on 12 February 2009

Catechol-O-methyltransferase (COMT) gene variants: possible association of the Val158Met variant with opiate addiction in Hispanic women

scientific article

Cell-specific effects of variants of the 68-base pair tandem repeat on prodynorphin gene promoter activity

scientific article published on 23 August 2010

Chronic Oxycodone Self-administration Altered Reward-related Genes in the Ventral and Dorsal Striatum of C57BL/6J Mice: An RNA-seq Analysis

scientific article published on 29 July 2018

Chronic administration of morphine is associated with a decrease in surface AMPA GluR1 receptor subunit in dopamine D1 receptor expressing neurons in the shell and non-D1 receptor expressing neurons in the core of the rat nucleus accumbens

scientific article published on 26 January 2008

Chronic escalating cocaine exposure, abstinence/withdrawal, and chronic re-exposure: Effects on striatal dopamine and opioid systems in C57BL/6J mice ⬇️

scientific article published on November 16, 2012

Chronic immobilization stress primes the hippocampal opioid system for oxycodone-associated learning in female but not male rats

scientific article published on 22 January 2019

Clinically utilized kappa-opioid receptor agonist nalfurafine combined with low-dose naltrexone prevents alcohol relapse-like drinking in male and female mice

scientific article published on 27 August 2019

Clock reset for alcoholism

scientific article published in January 2005

Clues to understanding the oxidation of estradiol in humans: effects of acute infectious hepatitis, autoimmune hepatitis, and chronic liver disease

scientific article

Combination of Clinically Utilized Kappa-Opioid Receptor Agonist Nalfurafine With Low-Dose Naltrexone Reduces Excessive Alcohol Drinking in Male and Female Mice

scientific article published on 02 May 2019

Common and specific liability to addiction: Approaches to association studies of opioid addiction ⬇️

scientific article published on April 27, 2012

Common liability to addiction and “gateway hypothesis”: Theoretical, empirical and evolutionary perspective ⬇️

scientific article published on January 18, 2012

Community-dwelling cocaine-dependent men and women respond differently to social stressors versus cocaine cues

scientific article

Conditioned place preference after single doses or "binge" cocaine in C57BL/6J and 129/J mice

scientific article published in October 2002

Corrected-QT intervals as related to methadone dose and serum level in methadone maintenance treatment (MMT) patients: a cross-sectional study

scientific article published in February 2007

Correlation between high methadone doses and methadone serum levels in methadone maintenance treatment (MMT) patients

scientific article published on 01 January 2007

Corrigendum: Salvinorin A, a kappa-opioid receptor agonist hallucinogen: pharmacology and potential template for novel pharmacotherapeutic agents in neuropsychiatric disorders

scientific article published on 30 November 2015

Corticotropin-Releasing Factor Testing Reveals a Dose-Dependent Difference in Methadone Maintained Vs Control Subjects ⬇️

scientific article published on March 26, 2003

Critical issues in the treatment of hepatitis C virus infection in methadone maintenance patients

scientific article published on 16 April 2008

Current status of opioid addiction treatment and related preclinical research

scientific article published on 02 October 2019

Decreased plasma membrane targeting of NMDA-NR1 receptor subunit in dendrites of medial nucleus tractus solitarius neurons in rats self-administering morphine

scientific article

Determination of Salvinorin A in body fluids by high performance liquid chromatography-atmospheric pressure chemical ionization

scientific article

Differential gene expression in the rat caudate putamen after "binge" cocaine administration: advantage of triplicate microarray analysis

scientific article published in June 2003

Discriminative Stimulus Properties of Opioid Ligands: Progress and Future Directions

scientific article

Dopamine gene variants in opioid addiction: comparison of dependent patients, nondependent users and healthy controls.

scientific article published on 6 December 2017

Dopaminergic pathway polymorphisms and heroin addiction: further support for association of CSNK1E variants

scientific article

Dose escalation and dose preference in extended-access heroin self-administration in Lewis and Fischer rats

scientific article

Dose preference and dose escalation in extended-access cocaine self-administration in Fischer and Lewis rats

scientific article

Downregulation of kappa-opioid receptors in basolateral amygdala and septum of rats withdrawn for 14 days from an escalating dose "binge" cocaine administration paradigm

scientific article

Drug addiction and stress-response genetic variability: association study in African Americans

scientific article

Drug-induced and genetic alterations in stress-responsive systems: Implications for specific addictive diseases

scientific article

Dynorphin A(1-17) biotransformation in striatum of freely moving rats using microdialysis and matrix-assisted laser desorption/ionization mass spectrometry

scientific article

Effect of chronic “binge cocaine” on basal levels and cocaine‐induced increases of dopamine in the caudate putamen and nucleus accumbens of C57BL/6J and 129/J mice ⬇️

scientific article published on December 1, 2003

Effect of ethnicity, gender and drug use history on achieving high rates of affirmative informed consent for genetics research: impact of sharing with a national repository ⬇️

scientific article published on January 25, 2011

Effect of the endogenous kappa opioid agonist dynorphin A(1-17) on cocaine-evoked increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice

scientific article

Effect of the kappa opioid agonist R-84760 on cocaine-induced increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice

scientific article

Effects of Adrenal Sensitivity, Stress- and Cue-Induced Craving, and Anxiety on Subsequent Alcohol Relapse and Treatment Outcomes ⬇️

scientific article published on May 2, 2011

Effects of Kappa opioid receptor blockade by LY2444296 HCl, a selective short-acting antagonist, during chronic extended access cocaine self-administration and re-exposure in rat

scientific article published on 08 January 2020

Effects of acute "binge" cocaine on mRNA levels of mu opioid receptor and neuropeptides in dopamine D1 or D3 receptor knockout mice

scientific article published in January 2007

Effects of acute "binge" cocaine on preprodynorphin, preproenkephalin, proopiomelanocortin, and corticotropin-releasing hormone receptor mRNA levels in the striatum and hypothalamic-pituitary-adrenal axis of mu-opioid receptor knockout mice

scientific article

Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats

scientific article published on 20 March 2004

Effects of gender and cigarette smoking on reactivity to psychological and pharmacological stress provocation

scientific article published on 5 March 2008

Effects of handling and vehicle injections on adrenocorticotropic and corticosterone concentrations in Sprague-Dawley compared with Lewis rats

scientific article published on January 2015

Effects of hepatitis C and HIV on cognition in women: data from the Women's Interagency HIV Study

scientific article

Effects of high-dose methadone maintenance on cocaine place conditioning, cocaine self-administration, and mu-opioid receptor mRNA expression in the rat brain

scientific article published on 12 October 2005

Effects of mesyl salvinorin B alone and in combination with naltrexone on alcohol deprivation effect in male and female mice

scientific article published on 26 February 2018

Effects of salvinorin A, a kappa-opioid hallucinogen, on a neuroendocrine biomarker assay in nonhuman primates with high kappa-receptor homology to humans

scientific article

Effects of selective D1- or D2-like dopamine receptor antagonists with acute "binge" pattern cocaine on corticotropin-releasing hormone and proopiomelanocortin mRNA levels in the hypothalamus

scientific article published in November 2004

Effects of the plant-derived hallucinogen salvinorin A on basal dopamine levels in the caudate putamen and in a conditioned place aversion assay in mice: agonist actions at kappa opioid receptors

scientific article

Effects of voluntary alcohol drinking on corticotropin-releasing factor and preprodynorphin mRNA levels in the central amygdala of Sardinian alcohol-preferring rats

scientific article published on 08 September 2013

Effects of withdrawal from chronic escalating-dose binge cocaine on conditioned place preference to cocaine and striatal preproenkephalin mRNA in C57BL/6J mice ⬇️

scientific article published on April 4, 2012

Escalation of drug use in persons dually diagnosed with opioid and cocaine dependence: Gender comparison and dimensional predictors

scientific article published on 22 October 2019

Estimating ancestral proportions in a multi-ethnic US sample: implications for studies of admixed populations ⬇️

scientific article published on July 5, 2012

Ethnic diversity of DNA methylation in the OPRM1 promoter region in lymphocytes of heroin addicts

scientific article published on 18 March 2010

Evidence for association of two variants of the nociceptin/orphanin FQ receptor gene OPRL1 with vulnerability to develop opiate addiction in Caucasians

scientific article published on April 2010

Evolving perspectives on neurobiological research on the addictions: celebration of the 30th anniversary of NIDA.

scientific article published in January 2004

Expression of Ephrin Receptors and Ligands in Postmortem Brains of HIV-Infected Subjects With and Without Cognitive Impairment ⬇️

scientific article published on January 12, 2013

Extended access oxycodone self-administration and neurotransmitter receptor gene expression in the dorsal striatum of adult C57BL/6 J mice

scientific article

Extreme marginalization: addiction and other mental health disorders, stigma, and imprisonment ⬇️

scientific article published on August 1, 2011

Former heroin addicts with or without a history of cocaine dependence are more impulsive than controls

scientific article

Frequency of recent cocaine and alcohol use affects drug craving and associated responses to stress and drug-related cues.

scientific article published in October 2005

Fructose:glucose ratios--a study of sugar self-administration and associated neural and physiological responses in the rat.

scientific article published on 22 May 2015

Functions of arginine vasopressin and its receptors: importance of human molecular genetics studies in bidirectional translational research

scientific article published on September 2011

Further evidence for association of GAL, GALR1 and NPY1R variants with opioid dependence

scientific article published on 06 August 2020

Gender differences in cardiovascular and corticoadrenal response to stress and drug cues in cocaine dependent individuals

scientific article published on 3 March 2006

Gender-specific association of functional prodynorphin 68 bp repeats with cannabis exposure in an African American cohort

scientific article published on 16 April 2018

Genes associated with addiction: alcoholism, opiate, and cocaine addiction

scientific article published on January 2004

Genetic Variant in the CRH-binding Protein Gene (CRHBP) is Associated With Cessation of Cocaine Use in Methadone Maintenance Patients With Opioid Addiction

scientific article published on 01 November 2019

Genetic Vulnerability to Opioid Addiction

scientific article published on 23 March 2020

Genetic diversity and linkage disequilibrium in the chemokine receptor CCR2-CCR5 region among individuals and populations

scientific article published on 05 September 2013

Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction

scientific article

Genetic variations in genes of the stress response pathway are associated with prolonged abstinence from heroin

scientific article published on 21 February 2018

Genetics of opiate addiction

scientific article

Genome-wide association study identifies genes that may contribute to risk for developing heroin addiction

scientific article

Glucocorticoid negative feedback in methadone-maintained former heroin addicts with ongoing cocaine dependence: dose-response to dexamethasone suppression

scientific article published in March 2006

Glutamatergic and GABAergic susceptibility loci for heroin and cocaine addiction in subjects of African and European ancestry

scientific article

Haplotype block structure of the genomic region of the mu opioid receptor gene ⬇️

scientific article published on December 16, 2010

Hepatitis C treatment, subcutaneous naltrexone implants, and methadone maintenance treatment

scientific article published on 01 September 2007

Hepatitis C virus and human immunodeficiency virus-1 co-infection in former heroin addicts in methadone maintenance treatment

scientific article

Heroin-induced locomotor activity and conditioned place preference in C57BL/6J and 129P3/J mice

scientific article

High methadone dose significantly reduces cocaine use in methadone maintenance treatment (MMT) patients

scientific article published in January 2006

High-throughput molecular haplotype analysis (allelic assignment) of single-nucleotide polymorphisms by fluorescent polymerase chain reaction

scientific article published in December 2004

History and current status of opioid maintenance treatments: blending conference session

scientific article

Human behavioral pharmacology, past, present, and future: symposium presented at the 50th annual meeting of the Behavioral Pharmacology Society

scientific article

Hypothalamic-pituitary-adrenal axis and sympatho-adreno-medullary responses during stress-induced and drug cue-induced cocaine craving states.

scientific article published on 4 July 2003

Hypothalamic-pituitary-adrenocortical (HPA) axis response and biotransformation of oral naltrexone: preliminary examination of relationship to family history of alcoholism

scientific article

Identification of substance use and dependence among patients with viral hepatitis

scientific article

Immediate withdrawal from chronic "binge" cocaine administration increases mu-opioid receptor mRNA levels in rat frontal cortex

scientific article published in June 2005

Impact of Pharmacological Manipulation of the κ-Opioid Receptor System on Self-grooming and Anhedonic-like Behaviors in Male Mice

scientific article published on 11 April 2019

Increased AMPA GluR1 receptor subunit labeling on the plasma membrane of dendrites in the basolateral amygdala of rats self-administering morphine

scientific article published in October 2005

Increased CRH mRNA levels in the rat amygdala during short-term withdrawal from chronic 'binge' cocaine

scientific article

Increased OPRM1 DNA methylation in lymphocytes of methadone-maintained former heroin addicts

scientific article

Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden

scientific article published in February 2005

Individual differences in gene expression of vasopressin, D2 receptor, POMC and orexin: vulnerability to relapse to heroin-seeking in rats

scientific article

Involvement of Endocannabinoids in Alcohol "Binge" Drinking: Studies of Mice with Human Fatty Acid Amide Hydrolase Genetic Variation and After CB1 Receptor Antagonists

scientific article published on 09 February 2016

Involvement of activated brain stress responsive systems in excessive and "relapse" alcohol drinking in rodent models: implications for therapeutics

scientific article published on 18 April 2018

Involvement of arginine vasopressin and V1b receptor in alcohol drinking in Sardinian alcohol-preferring rats

scientific article

Involvement of arginine vasopressin and V1b receptor in heroin withdrawal and heroin seeking precipitated by stress and by heroin

scientific article published on 18 April 2007

Involvement of dynorphin and kappa opioid receptor in yohimbine-induced reinstatement of heroin seeking in rats

scientific article published on 26 February 2013

Involvement of tissue plasminogen activator in stress responsivity during acute cocaine withdrawal in mice.

scientific article published on 28 July 2010

Kappa Opioid Receptors and Mu Opioid Receptors as Combined Targets for Medication Development for Alcoholism

scientific article published on 01 December 2019

LC-MS/MS quantification of salvinorin A from biological fluids

scientific article published on December 2013

Limited effects of beta-endorphin compared to loperamide or fentanyl in a neuroendocrine biomarker assay in non-human primates

scientific article

Locomotion, stereotypy, and dopamine D1 receptors after chronic "binge" cocaine in C57BL/6J and 129/J mice

scientific article published in April 2003

Markers for hepatitis A, B and C in methadone maintained patients: an unexpectedly high co-infection with silent hepatitis B.

scientific article published on April 2008

Measuring the incentive value of escalating doses of heroin in heroin-dependent Fischer rats during acute spontaneous withdrawal

scientific article published on 7 July 2011

Medications for substance use disorders (SUD): emerging approaches.

scientific article published on 21 October 2017

Methadone Medical Maintenance: An Early 21st-Century Perspective

scientific article published on 25 June 2015

Methadone maintenance treatment experience in Macao--prospective follow-up for initial 4.5 years

scientific article published in September 2013

Microarray studies of psychostimulant-induced changes in gene expression

scientific article published in March 2005

Mouse model of the OPRM1 (A118G) polymorphism: differential heroin self-administration behavior compared with wild-type mice

scientific article

Mu opioid receptor and orexin/hypocretin mRNA levels in the lateral hypothalamus and striatum are enhanced by morphine withdrawal

scientific article published in October 2006

Mu-opioid receptor A118G polymorphism in healthy volunteers affects hypothalamic-pituitary-adrenal axis adrenocorticotropic hormone stress response to metyrapone

scientific article published on 20 April 2011

Murine model of OPRM1 A118G alters oxycodone self-administration and locomotor activation, but not conditioned place preference

scientific article published on 25 November 2019

NIDA's commitment to tackling drug abuse

scientific article published in August 2004

Nalmefene induced elevation in serum prolactin in normal human volunteers: partial kappa opioid agonist activity?

scientific article

Naltrexone and nalmefene attenuate cocaine place preference in male mice

scientific article published on 23 July 2018

Naltrexone decreases craving and alcohol self-administration in alcohol-dependent subjects and activates the hypothalamo-pituitary-adrenocortical axis.

scientific article published on 22 January 2002

Neurocognitive and neuroinflammatory correlates of PDYN and OPRK1 mRNA expression in the anterior cingulate in postmortem brain of HIV-infected subjects

scientific article published on 09 January 2014

Neuroendocrine effects of naltrexone versus nalmefene in humans

scientific article published on 12 February 2020

Neuropathic and chronic pain stimuli downregulate central mu-opioid and dopaminergic transmission

scientific article published on 12 May 2010

Non-medical Cannabis Self-Exposure as a Dimensional Predictor of Opioid Dependence Diagnosis: A Propensity Score Matched Analysis.

scientific article published on 27 June 2018

Nuclear transcriptional changes in hypothalamus of Pomc enhancer knockout mice after excessive alcohol drinking

scientific article published on 08 August 2019

On blending practice and research: the search for commonalities in substance abuse treatment

scientific article published on June 2006

One-year and cumulative retention as predictors of success in methadone maintenance treatment: a comparison of two clinics in the United States and Israel

scientific article published on January 2008

Opiate addiction and cocaine addiction: underlying molecular neurobiology and genetics

scientific article

Opiate and cocaine addiction: from bench to clinic and back to the bench

scientific article published on 18 January 2009

Opioids, dopamine, stress, and the addictions.

scientific article

Oprm1 A112G, a single nucleotide polymorphism, alters expression of stress-responsive genes in multiple brain regions in male and female mice

scientific article published on 19 July 2018

Optimizing primer--probe design for fluorescent PCR.

scientific article

Overlapping dopaminergic pathway genetic susceptibility to heroin and cocaine addictions in African Americans

scientific article

Overview and historical perspective of four papers presented on research related to the endogenous opioid system

scientific article published on 18 April 2010

Oxycodone Self-Administration Induces Alterations in Expression of Integrin, Semaphorin and Ephrin Genes in the Mouse Striatum.

scientific article

Oxycodone-induced conditioned place preference and sensitization of locomotor activity in adolescent and adult mice

scientific article published on July 2013

PET imaging of leptin biodistribution and metabolism in rodents and primates.

scientific article

Persistent increase in hypothalamic arginine vasopressin gene expression during protracted withdrawal from chronic escalating-dose cocaine in rodents

scientific article published on 15 June 2011

Persistent upregulation of mu-opioid, but not adenosine, receptors in brains of long-term withdrawn escalating dose "binge" cocaine-treated rats

scientific article published in September 2005

Personality as a risk factor for illicit opioid use and a protective factor for illicit opioid dependence

scientific article published on 14 October 2014

Pharmacogenetics and human molecular genetics of opiate and cocaine addictions and their treatments

scientific article

Pharmacokinetics of the plant-derived kappa-opioid hallucinogen salvinorin A in nonhuman primates

scientific article published in December 2005

Pharmacotherapy in the treatment of addiction: methadone

scientific article

Pharmacotherapy of addictions

scientific article

Polymorphisms of the kappa opioid receptor and prodynorphin genes: HIV risk and HIV natural history

scientific article published on May 2013

Potentially functional polymorphism in the promoter region of prodynorphin gene may be associated with protection against cocaine dependence or abuse

scientific article

Primary structure of guinea pig preprodynorphin and preproenkephalin mRNAs: multiple transcription initiation sites for preprodynorphin

scientific article published in March 2004

Prodynorphin gene promoter repeat associated with cocaine/alcohol codependence

scientific article published on 8 June 2007

Prospective study of QTc changes among former opiate addicts since admission to methadone maintenance treatment: benzodiazepine risk

scientific article published in November 2013

QT interval screening in methadone maintenance treatment: report of a SAMHSA expert panel

scientific article

Quantification of multiple mRNA levels in rat brain regions using real time optical PCR.

scientific article published in April 2003

Re-evaluation of the KMSK scales, rapid dimensional measures of self-exposure to specific drugs: Gender-specific features

scientific article published on 21 July 2018

Reactivity to laboratory stress provocation predicts relapse to cocaine

scientific article

Redefinition of the human kappa opioid receptor gene (OPRK1) structure and association of haplotypes with opiate addiction.

scientific article published in December 2004

Region-specific changes in the subcellular distribution of AMPA receptor GluR1 subunit in the rat ventral tegmental area after acute or chronic morphine administration

scientific article published on September 2008

Relative expression of mRNA for the somatostatin receptors in the caudate putamen of C57BL/6J and 129P3/J mice: strain and heroin effects

scientific article published on 15 May 2010

Repeated Administration of Opra Kappa (LY2456302), a Novel, Short-Acting, Selective KOP-r Antagonist, in Persons with and Without Cocaine Dependence

scientific article published on 31 August 2017

Repeated Administration of Opra Kappa (LY2456302), a Novel, Short-Acting, Selective KOP-r Antagonist, in Persons with and without Cocaine Dependence

scientific article published in March 2018

Response to corticotropin-releasing hormone infusion in cocaine-dependent individuals

scientific article published on April 2009

Salvinorin A, a kappa-opioid receptor agonist hallucinogen: pharmacology and potential template for novel pharmacotherapeutic agents in neuropsychiatric disorders

scientific article

Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment

scientific article published on February 2010

Semisynthetic neoclerodanes as kappa opioid receptor probes ⬇️

scientific article published on May 1, 2012

Setting priorities for genomic research

scientific article

Sex Differences in Neuroplasticity- and Stress-Related Gene Expression and Protein Levels in the Rat Hippocampus Following Oxycodone Conditioned Place Preference

scientific article published on 07 May 2019

Sex and chronic stress differentially alter phosphorylated mu and delta opioid receptor levels in the rat hippocampus following oxycodone conditioned place preference

scientific article published on 24 September 2019

Sex differences after chronic stress in the expression of opioid-, stress- and neuroplasticity-related genes in the rat hippocampus.

scientific article

Sex differences in responsiveness to the prescription opioid oxycodone in mice

scientific article published on 14 June 2016

Sex differences in the effect of bupropion and naltrexone combination on alcohol drinking in mice

scientific article published on 13 April 2019

Sex differences in the rat hippocampal opioid system after oxycodone conditioned place preference

scientific article published on 11 October 2018

Sex-specific dissociations in autonomic and HPA responses to stress and cues in alcohol-dependent patients with cocaine abuse

scientific article published on 30 September 2009

Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands: Toward in Vitro Models of in Vivo Responses

scientific article published on 31 July 2019

Something of value: the introduction of contingency management interventions into the New York City Health and Hospital Addiction Treatment Service

scientific article published in January 2005

Steady-dose and escalating-dose "binge" administration of cocaine alter expression of behavioral stereotypy and striatal preprodynorphin mRNA levels in rats

scientific article

Steady-state methadone blocks cocaine seeking and cocaine-induced gene expression alterations in the rat brain

scientific article

Strain and cocaine-induced differential opioid gene expression may predispose Lewis but not Fischer rats to escalate cocaine self-administration.

scientific article published on 08 January 2016

Stress responsivity, addiction, and a functional variant of the human mu-opioid receptor gene

scientific article published on April 2007

Stress, dysregulation of drug reward pathways, and the transition to drug dependence

scientific article

Stress-induced cocaine craving and hypothalamic-pituitary-adrenal responses are predictive of cocaine relapse outcomes

scientific article published in March 2006

Structurally-Related Kappa Opioid Receptor Agonists with Substantial Differential Signaling Bias: Neuroendocrine and Behavioral Effects in C57BL6 Mice

scientific article published on 4 April 2018

Suppressed Prolactin Response to Dynorphin A1–13 in Methadone-Maintained Versus Control Subjects ⬇️

scientific article published on May 2, 2003

Suppression of hypothalamic-pituitary-adrenal axis by acute heroin challenge in rats during acute and chronic withdrawal from chronic heroin administration

scientific article published on 16 June 2013

Susceptibility loci for heroin and cocaine addiction in the serotonergic and adrenergic pathways in populations of different ancestry

scientific article published on 31 July 2015

Synaptic Plasticity and Signal Transduction Gene Polymorphisms and Vulnerability to Drug Addictions in Populations of European or African Ancestry

scientific article

Synergistic blockade of alcohol escalation drinking in mice by a combination of novel kappa opioid receptor agonist Mesyl Salvinorin B and naltrexone

scientific article published on 2 March 2017

TPH2 and TPH1: association of variants and interactions with heroin addiction

scientific article

The BiolAD-DB system : an informatics system for clinical and genetic data

scientific article

The Kreek-McHugh-Schluger-Kellogg scale: a new, rapid method for quantifying substance abuse and its possible applications

scientific article published in March 2003

The Personality Assessment Inventory Drug Problems Scale: a validity analysis

scientific article published in August 2002

The discriminative effects of the kappa-opioid hallucinogen salvinorin A in nonhuman primates: dissociation from classic hallucinogen effects

scientific article

The effects of herkinorin, the first mu-selective ligand from a salvinorin A-derived scaffold, in a neuroendocrine biomarker assay in nonhuman primates

scientific article

The genetics of the opioid system and specific drug addictions

scientific article published on May 2012

The nociceptin/orphanin FQ receptor agonist Ro 64-6198 reduces alcohol self-administration and prevents relapse-like alcohol drinking

scientific article

The plant-derived hallucinogen, salvinorin A, produces ?-opioid agonist-like discriminative effects in rhesus monkeys ⬇️

scientific article published on October 30, 2003

The single nucleotide polymorphism A118G alters functional properties of the human mu opioid receptor

scientific article

The use of levo-alpha-acetylmethadol (LAAM) in methadone patients who have not achieved heroin abstinence

scientific article published in January 2002

The μ-opioid receptor nonsynonymous variant 118A>G is associated with prolonged abstinence from heroin without agonist treatment

scientific article published on 4 October 2017

Tissue plasminogen activator modulates the cellular and behavioral response to cocaine.

scholarly article

Tissue-specific DNA methylation of the human prodynorphin gene in post-mortem brain tissues and PBMCs ⬇️

scientific article published on April 1, 2011

Tolerance and sensitization to chronic escalating dose heroin following extended withdrawal in Fischer rats: possible role of mu-opioid receptors ⬇️

scientific article published on July 25, 2012

Topical capsaicin-induced allodynia in unanesthetized primates: pharmacological modulation

scientific article

Treatment-like steady-state methadone in rats interferes with incubation of cocaine sensitization and associated alterations in gene expression ⬇️

scientific article published on 13 July 2011

Unconditioned behavioral effects of the powerful kappa-opioid hallucinogen salvinorin A in nonhuman primates: fast onset and entry into cerebrospinal fluid

scientific article

V1b Receptor Antagonist SSR149415 and Naltrexone Synergistically Decrease Excessive Alcohol Drinking in Male and Female Mice

scientific article published on 3 November 2017

VMAT2 gene (SLC18A2) variants associated with a greater risk for developing opioid dependence

scientific article published on 15 April 2019

Variants of opioid genes and response to treatment of opioid use disorder with buprenorphine-naloxone versus extended-release naltrexone in Caucasians

scientific article published on 27 August 2020

Variants of opioid system genes are associated with non-dependent opioid use and heroin dependence.

scientific article

Voluntary alcohol drinking enhances proopiomelanocortin gene expression in nucleus accumbens shell and hypothalamus of Sardinian alcohol-preferring rats

scientific article published on 22 June 2012

κ-opioid receptor/dynorphin system: genetic and pharmacotherapeutic implications for addiction ⬇️

scientific article published on June 16, 2012

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