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List of works by Deniz Dalkara

A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina

scientific article

A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells

scientific article

AAV mediated GDNF secretion from retinal glia slows down retinal degeneration in a rat model of retinitis pigmentosa

scientific article published on 26 April 2011

AAV-mediated gene delivery in Dp71-null mouse model with compromised barriers

scientific article published on 31 December 2013

AAV-mediated gene therapy in Dystrophin-Dp71 deficient mouse leads to blood-retinal barrier restoration and oedema reabsorption.

scientific article published on 10 June 2016

Advancing therapeutic strategies for inherited retinal degeneration: recommendations from the Monaciano Symposium

scientific article

Cationic oligonucleotide-peptide conjugates with aggregating properties enter efficiently into cells while maintaining hybridization properties and enzymatic recognition

scientific article published on 01 August 2006

Cell type-specific Nogo-A gene ablation promotes axonal regeneration in the injured adult optic nerve

scientific article (publication date: February 2015)

Changes in adeno-associated virus-mediated gene delivery in retinal degeneration

scientific article published on May 2010

Developments in gene delivery vectors for ocular gene therapy

scientific article published on May 2015

Emerging therapies for inherited retinal degeneration

scientific article published on December 2016

Enhanced gene delivery to the neonatal retina through systemic administration of tyrosine-mutated AAV9.

scientific article published on 20 October 2011

Functional rescue of cone photoreceptors in retinitis pigmentosa

scientific article published on July 2013

Gene therapy for inherited retinal degenerations

scientific article published on 11 March 2014

Gene therapy for the eye focus on mutation-independent approaches

scientific article published on February 2015

Genotypic and phenotypic characterization of P23H line 1 rat model

scientific article published on 26 May 2015

Imaging light responses of foveal ganglion cells in the living macaque eye.

scientific article

In vivo-directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous

scientific article published in June 2013

Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous

scientific article published in 2009

Insight into the mechanisms of enhanced retinal transduction by the engineered AAV2 capsid variant -7m8.

scientific article published on 4 June 2016

Intracisternal delivery of NFκB-inducible scAAV2/9 reveals locoregional neuroinflammation induced by systemic kainic acid treatment.

scientific article

Intravitreal injection of AAV2 transduces macaque inner retina

scientific article

Let There Be Light: Gene and Cell Therapy for Blindness

scientific article published on 11 January 2016

LiGluR restores visual responses in rodent models of inherited blindness

scientific article

Melanopsin Variants as Intrinsic Optogenetic On and Off Switches for Transient versus Sustained Activation of G Protein Pathways.

scientific article published on 7 April 2016

Misguidance and modulation of axonal regeneration by Stat3 and Rho/ROCK signaling in the transparent optic nerve.

scientific article

Molecular evolution of adeno-associated virus for enhanced glial gene delivery

scientific article published on 11 August 2009

Neuronal Nogo-A upregulation does not contribute to ER stress-associated apoptosis but participates in the regenerative response in the axotomized adult retina.

scientific article

Red-shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina.

scientific article published on 27 September 2016

Retinoschisin gene therapy in photoreceptors, Müller glia or all retinal cells in the Rs1h-/- mouse.

scientific article published on 3 April 2014

Rod-derived cone viability factor promotes cone survival by stimulating aerobic glycolysis

scientific article

Spinocerebellar ataxia type 6 protein aggregates cause deficits in motor learning and cerebellar plasticity.

scientific article published on June 2015

Suppression of cervical carcinoma cell growth by intracytoplasmic codelivery of anti-oncoprotein E6 antibody and small interfering RNA.

scientific article

Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques.

scientific article published on 9 February 2012

Targeting channelrhodopsin-2 to ON-bipolar cells with vitreally administered AAV Restores ON and OFF visual responses in blind mice

scientific article

The Thioredoxin Encoded by the Rod-Derived Cone Viability Factor Gene Protects Cone Photoreceptors Against Oxidative Stress

scientific article published on 29 March 2016

The primate model for understanding and restoring vision

scientific article published on 23 December 2019

Towards optogenetic vision restoration with high resolution

scientific article published on 15 July 2020

Using Adeno-associated Virus as a Tool to Study Retinal Barriers in Disease

scientific article published on 19 April 2015

Vertebrate cone opsins enable sustained and highly sensitive rapid control of Gi/o signaling in anxiety circuitry

scientific article published in March 2014

Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration

scientific article

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