List of works - Astrid Westendorf

Acquired IFNγ resistance impairs anti-tumor immunity and gives rise to T-cell-resistant melanoma lesions

scientific article

Analysis of Cd14 as a genetic modifier of experimental inflammatory bowel disease (IBD) in mice.

scientific article

CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production

scientific article

CEACAM1 regulates CD8+ T cell immunity and protects from severe pathology during Citrobacter rodentium induced colitis

scientific article published on 10 June 2020

Cd14, Gbp1, and Pla2g2a: three major candidate genes for experimental IBD identified by combining QTL and microarray analyses

scientific article published on May 2006

Colonic gene silencing using siRNA-loaded calcium phosphate/PLGA nanoparticles ameliorates intestinal inflammation in vivo

scientific article published on 14 December 2015

Combination of nanoparticle-based therapeutic vaccination and transient ablation of regulatory T cells enhances anti-viral immunity during chronic retroviral infection

scientific article

DC-Derived IL-10 Modulates Pro-inflammatory Cytokine Production and Promotes Induction of CD4+IL-10+ Regulatory T Cells during Plasmodium yoelii Infection

scientific article published on 28 February 2017

Differential expression of GPR15 on T cells during ulcerative colitis

scientific article

Distinct kinetics in the frequency of peripheral CD4+ T cells in patients with ulcerative colitis experiencing a flare during treatment with mesalazine or with a herbal preparation of myrrh, chamomile, and coffee charcoal

scientific article published on 21 August 2014

Efficient nucleic acid delivery to murine regulatory T cells by gold nanoparticle conjugates

scientific article published on 6 July 2016

Extracellular Adenosine Production by ecto-5'-Nucleotidase (CD73) Enhances Radiation-Induced Lung Fibrosis

scientific article

G protein-coupled receptor 83 overexpression in naive CD4+CD25- T cells leads to the induction of Foxp3+ regulatory T cells in vivo

scientific article

Genetically induced pancreatic adenocarcinoma is highly immunogenic and causes spontaneous tumor-specific immune responses

scientific article published on January 2006

Genomic peculiarity of coding sequences and metabolic potential of probiotic Escherichia coli strain Nissle 1917 inferred from raw genome data

scientific article published in May 2005

Gut inflammation can boost horizontal gene transfer between pathogenic and commensal Enterobacteriaceae

scientific article published on 9 January 2012

Hydrocortisone fails to abolish NF-κB1 protein nuclear translocation in deletion allele carriers of the NFKB1 promoter polymorphism (-94ins/delATTG) and is associated with increased 30-day mortality in septic shock.

scientific article

Hypoxia Enhances Immunosuppression by Inhibiting CD4+ Effector T Cell Function and Promoting Treg Activity

scientific article

IL10-Deficiency in CD4⁺ T Cells Exacerbates the IFNγ and IL17 Response During Bacteria Induced Colitis.

scientific article published on July 2015

Intestinal helminth infection drives carcinogenesis in colitis-associated colon cancer.

scientific article published on 22 September 2017

Local Induction of Immunosuppressive CD8+ T Cells in the Gut-Associated Lymphoid Tissues ⬇️

scientific article published on October 20, 2010

Local delivery of siRNA-loaded calcium phosphate nanoparticles abates pulmonary inflammation

scientific article published on 8 August 2017

Mitochondrial DNA: An Endogenous Trigger for Immune Paralysis

scientific article published on 15 January 2016

Neuropilin 1 deficiency on CD4+Foxp3+ regulatory T cells impairs mouse melanoma growth

scientific article

Neuropilin-1: a surface marker of regulatory T cells

scientific article published on March 2004

On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes

scientific article published in December 2005

Plasmodium yoelii infection of BALB/c mice results in expansion rather than induction of CD4(+) Foxp3(+) regulatory T cells

scientific article

Probiotic Escherichia coli Nissle 1917 inhibits leaky gut by enhancing mucosal integrity

scientific article

Prophylactic and therapeutic vaccination with a nanoparticle-based peptide vaccine induces efficient protective immunity during acute and chronic retroviral infection.

scientific article

Quantitative Comparison of Abundance Structures of Generalized Communities: From B-Cell Receptor Repertoires to Microbiomes

scientific article

Regulatory T cells and T-cell-derived IL-10 interfere with effective anti-cytomegalovirus immune response

scientific article published on 29 July 2014

Regulatory T cells as targets for immunotherapy of autoimmunity and inflammation

scientific article published on December 2008

Relevance of Foxp3⁺ regulatory T cells for early and late phases of murine sepsis

scientific article published on 2 July 2015

Retinoic acid‐induced gut tropism improves the protective capacity of Treg in acute but not in chronic gut inflammation ⬇️

scientific article published on September 1, 2010

Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota

scientific article

Signatures of human regulatory T cells: an encounter with old friends and new players

scientific article published on January 2006

T cells, dendritic cells and epithelial cells in intestinal homeostasis

scientific article published on 24 September 2009

Targeting Antigens to Dec-205 on Dendritic Cells Induces Immune Protection in Experimental Colitis in Mice

scientific article

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

scientific article (publication date: May 2008)

The host response to the probiotic Escherichia coli strain Nissle 1917: specific up-regulation of the proinflammatory chemokine MCP-1

scientific article

The type of adjuvant strongly influences the T-cell response during nanoparticle-based immunization

scientific article published on 27 August 2013

Thorax irradiation triggers a local and systemic accumulation of immunosuppressive CD4+ FoxP3+ regulatory T cells

scientific article published on 25 April 2014

Three-dimensional tumor spheroids for in vitro analysis of bacteria as gene delivery vectors in tumor therapy.

scientific article published on 12 December 2015

Virus-Induced Type I Interferon Deteriorates Control of Systemic Pseudomonas Aeruginosa Infection

scientific article published on 27 July 2015

List of works by Astrid Westendorf

Acquired IFNγ resistance impairs anti-tumor immunity and gives rise to T-cell-resistant melanoma lesions

Analysis of Cd14 as a genetic modifier of experimental inflammatory bowel disease (IBD) in mice.

CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production

CEACAM1 regulates CD8+ T cell immunity and protects from severe pathology during Citrobacter rodentium induced colitis

Cd14, Gbp1, and Pla2g2a: three major candidate genes for experimental IBD identified by combining QTL and microarray analyses

Colonic gene silencing using siRNA-loaded calcium phosphate/PLGA nanoparticles ameliorates intestinal inflammation in vivo

Combination of nanoparticle-based therapeutic vaccination and transient ablation of regulatory T cells enhances anti-viral immunity during chronic retroviral infection

DC-Derived IL-10 Modulates Pro-inflammatory Cytokine Production and Promotes Induction of CD4+IL-10+ Regulatory T Cells during Plasmodium yoelii Infection

Differential expression of GPR15 on T cells during ulcerative colitis

Distinct kinetics in the frequency of peripheral CD4+ T cells in patients with ulcerative colitis experiencing a flare during treatment with mesalazine or with a herbal preparation of myrrh, chamomile, and coffee charcoal

Efficient nucleic acid delivery to murine regulatory T cells by gold nanoparticle conjugates

Extracellular Adenosine Production by ecto-5'-Nucleotidase (CD73) Enhances Radiation-Induced Lung Fibrosis

G protein-coupled receptor 83 overexpression in naive CD4+CD25- T cells leads to the induction of Foxp3+ regulatory T cells in vivo

Genetically induced pancreatic adenocarcinoma is highly immunogenic and causes spontaneous tumor-specific immune responses

Genomic peculiarity of coding sequences and metabolic potential of probiotic Escherichia coli strain Nissle 1917 inferred from raw genome data

Gut inflammation can boost horizontal gene transfer between pathogenic and commensal Enterobacteriaceae

Hydrocortisone fails to abolish NF-κB1 protein nuclear translocation in deletion allele carriers of the NFKB1 promoter polymorphism (-94ins/delATTG) and is associated with increased 30-day mortality in septic shock.

Hypoxia Enhances Immunosuppression by Inhibiting CD4+ Effector T Cell Function and Promoting Treg Activity

IL10-Deficiency in CD4⁺ T Cells Exacerbates the IFNγ and IL17 Response During Bacteria Induced Colitis.

Intestinal helminth infection drives carcinogenesis in colitis-associated colon cancer.

Local Induction of Immunosuppressive CD8+ T Cells in the Gut-Associated Lymphoid Tissues ⬇️

Local delivery of siRNA-loaded calcium phosphate nanoparticles abates pulmonary inflammation

Mitochondrial DNA: An Endogenous Trigger for Immune Paralysis

Neuropilin 1 deficiency on CD4+Foxp3+ regulatory T cells impairs mouse melanoma growth

Neuropilin-1: a surface marker of regulatory T cells

On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes

Plasmodium yoelii infection of BALB/c mice results in expansion rather than induction of CD4(+) Foxp3(+) regulatory T cells

Probiotic Escherichia coli Nissle 1917 inhibits leaky gut by enhancing mucosal integrity

Prophylactic and therapeutic vaccination with a nanoparticle-based peptide vaccine induces efficient protective immunity during acute and chronic retroviral infection.

Quantitative Comparison of Abundance Structures of Generalized Communities: From B-Cell Receptor Repertoires to Microbiomes

Regulatory T cells and T-cell-derived IL-10 interfere with effective anti-cytomegalovirus immune response

Regulatory T cells as targets for immunotherapy of autoimmunity and inflammation

Relevance of Foxp3⁺ regulatory T cells for early and late phases of murine sepsis

Retinoic acid‐induced gut tropism improves the protective capacity of Treg in acute but not in chronic gut inflammation ⬇️

Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota

Signatures of human regulatory T cells: an encounter with old friends and new players

T cells, dendritic cells and epithelial cells in intestinal homeostasis

Targeting Antigens to Dec-205 on Dendritic Cells Induces Immune Protection in Experimental Colitis in Mice

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

The host response to the probiotic Escherichia coli strain Nissle 1917: specific up-regulation of the proinflammatory chemokine MCP-1

The type of adjuvant strongly influences the T-cell response during nanoparticle-based immunization

Thorax irradiation triggers a local and systemic accumulation of immunosuppressive CD4+ FoxP3+ regulatory T cells

Three-dimensional tumor spheroids for in vitro analysis of bacteria as gene delivery vectors in tumor therapy.

Virus-Induced Type I Interferon Deteriorates Control of Systemic Pseudomonas Aeruginosa Infection