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List of works by Victoria Cowling

A Conserved Myc Protein Domain, MBIV, Regulates DNA Binding, Apoptosis, Transformation, and G2 Arrest.

scientific article published in July 2006

A conserved Myc protein domain, MBIV, regulates DNA binding, apoptosis, transformation, and G2 arrest.

scientific article

A core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum response

scientific article

A novel RNA pol II CTD interaction site on the mRNA capping enzyme is essential for its allosteric activation

scientific article published on 16 February 2021

An N-Myc truncation analogous to c-Myc-S induces cell proliferation independently of transactivation but dependent on Myc homology box II.

scientific article published on 20 August 2007

Binding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi

scientific article

Burkitt's lymphoma-associated c-Myc mutations converge on a dramatically altered target gene response and implicate Nol5a/Nop56 in oncogenesis

scientific article published on 09 September 2013

CAPAM: The mRNA Cap Adenosine N6-Methyltransferase

scientific article published on 21 January 2019

CDK1-Cyclin B1 Activates RNMT, Coordinating mRNA Cap Methylation with G1 Phase Transcription.

scientific article published on March 2016

CMTR1 is recruited to transcription start sites and promotes ribosomal protein and histone gene expression in embryonic stem cells

scientific article published on 09 February 2022

Cap-binding complex (CBC).

scientific article published on January 2014

Caspase-6 is the direct activator of caspase-8 in the cytochrome c-induced apoptosis pathway: absolute requirement for removal of caspase-6 prodomain

scientific article (publication date: October 2002)

DHX15 regulates CMTR1-dependent gene expression and cell proliferation

scientific article published on 01 June 2018

Direct High-Throughput Screening Assay for mRNA Cap Guanine-N7 Methyltransferase Activity

scientific article published on 07 April 2020

E-cadherin repression contributes to c-Myc-induced epithelial cell transformation

scientific article published on 4 December 2006

E2F1-dependent methyl cap formation requires RNA pol II phosphorylation

scientific article published on June 2012

Enhanced mRNA cap methylation increases cyclin D1 expression and promotes cell transformation

scientific article

HATs off to capping: a new mechanism for Myc.

scientific article published on 8 April 2007

Human IFIT1 Inhibits mRNA Translation of Rubulaviruses but Not Other Members of the Paramyxoviridae Family.

scientific article published on 10 August 2016

Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells

scientific article published in December 2005

Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM.

scientific article

Myc Regulation of mRNA Cap Methylation

scientific article

Myc and mRNA capping.

scientific article published on 27 March 2014

Myc up-regulates formation of the mRNA methyl cap.

scientific article published on December 2010

Nestin is expressed in the basal/myoepithelial layer of the mammary gland and is a selective marker of basal epithelial breast tumors

scientific article published on January 2007

Oncogenic PIK3CA mutations increase dependency on the mRNA cap methyltransferase, RNMT, in breast cancer cells

scientific article published on 01 April 2019

Positioning Europe for the EPITRANSCRIPTOMICS challenge.

scientific article published on 19 April 2018

RAM function is dependent on Kapβ2-mediated nuclear entry

scientific article published on February 2014

RAM/Fam103a1 is required for mRNA cap methylation

scientific article

Regulation and function of CMTR1-dependent mRNA cap methylation.

scientific article published on 2 October 2017

Regulation of mRNA capping in the cell cycle.

scientific article published on 28 October 2016

S-adenosyl homocysteine hydrolase is required for Myc-induced mRNA cap methylation, protein synthesis, and cell proliferation.

scientific article published on 5 October 2009

SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation

scientific article published on 23 March 2015

Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes.

scientific article published on July 2015

Specific regulation of mRNA cap methylation by the c-Myc and E2F1 transcription factors

scientific article published on 12 January 2009

The Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA binding

scientific journal article

The eukaryotic translation initiation factor eIF4E elevates steady-state m7G capping of coding and noncoding transcripts

scientific article published on 14 October 2020

The impact of KLF2 modulation on the transcriptional program and function of CD8 T cells

scientific article

The mRNA cap methyltransferase gene TbCMT1 is not essential in vitro but is a virulence factor in vivo for bloodstream form Trypanosoma brucei

scientific article published in PLoS ONE

Transcription-independent functions of MYC: regulation of translation and DNA replication

scientific article published on 13 August 2008

Victoria Cowling

scientific article published in August 2015

c-Myc co-ordinates mRNA cap methylation and ribosomal RNA production

scientific article published on December 2016

c-Myc deregulation induces mRNA capping enzyme dependency.

scientific article published on 16 October 2016

c-Myc transforms human mammary epithelial cells through repression of the Wnt inhibitors DKK1 and SFRP1

scientific article

mRNA Cap Methylation in Pluripotency and Differentiation

scientific article published on 20 July 2016

mRNA Cap Methyltransferase, RNMT-RAM, Promotes RNA Pol II-Dependent Transcription

scientific article published in May 2018

mRNA cap regulation in mammalian cell function and fate

scientific article published on 09 October 2018

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