List of works - Katrin Rittinger

Activation and assembly of the NADPH oxidase: a structural perspective

scientific article

Advanced rules of relays

scientific article published on 01 November 2020

Architecture of the p40-p47-p67phox complex in the resting state of the NADPH oxidase. A central role for p67phox

scientific article (publication date: 22 March 2002)

Cbl promotes clustering of endocytic adaptor proteins.

scientific article

Characterisation of class VI TRIM RING domains: linking RING activity to C-terminal domain identity

scientific article published on 26 April 2019

Conformational stability of dimeric HIV-1 and HIV-2 reverse transcriptases

scientific article

Control of mitotic exit in budding yeast. In vitro regulation of Tem1 GTPase by Bub2 and Bfa1.

scientific article

Crucial structural role for the PH and C1 domains of the Vav1 exchange factor

scientific article

Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP

scientific article

Crystallization of SHARPIN using an automated two-dimensional grid screen for optimization

scientific article

Determinants of E2-ubiquitin conjugate recognition by RBR E3 ligases

scientific article

Determination of the pKa of the N-terminal amino group of ubiquitin by NMR.

scientific article published on 2 March 2017

Dimerization kinetics of HIV-1 and HIV-2 reverse transcriptase: a two step process

scientific article published on February 1995

Does it take two to tango? RING domain self-association and activity in TRIM E3 ubiquitin ligases

scientific article published on 10 November 2020

Editorial overview: Multi-protein assemblies in signaling

scholarly article by Deborah Fass published in December 2014

Fragment-Based Covalent Ligand Screening Enables Rapid Discovery of Inhibitors for the RBR E3 Ubiquitin Ligase HOIP

scientific article published on 04 February 2019

Function of the nucleotide exchange activity of vav1 in T cell development and activation

scientific article

Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity

scientific article

In Vitro Analysis of Tem1 GTPase Activity and Regulation by the Bfa1/Bub2 GAP.

scientific article published in January 2017

In silico phosphorylation of the autoinhibited form of p47(phox): insights into the mechanism of activation

scientific article

Interaction between NOD2 and CARD9 involves the NOD2 NACHT and the linker region between the NOD2 CARDs and NACHT domain

scientific article published on 21 June 2014

Interactions between Cdc42 and the scaffold protein Scd2: requirement of SH3 domains for GTPase binding

scientific article

Interface peptides as structure-based human immunodeficiency virus reverse transcriptase inhibitors

scientific article

Isoform-selective interaction of the adaptor protein Tks5/FISH with Sos1 and dynamins

scientific article

LUBAC synthesizes linear ubiquitin chains via a thioester intermediate

scientific article

LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes

scientific article published on 6 December 2015

Linear ubiquitin chains: enzymes, mechanisms and biology

scientific article

Linear ubiquitination by LUBEL has a role in Drosophila heat stress response.

scientific article published on 04 October 2016

Mechanism and function of Vav1 localisation in TCR signalling.

scientific article published on 6 September 2012

MgF(3)(-) as a transition state analog of phosphoryl transfer

scientific article

Molecular basis of phosphorylation-induced activation of the NADPH oxidase

scientific article (publication date: 2 May 2003)

Molecular insights into RBR E3 ligase ubiquitin transfer mechanisms

scientific article published on 16 June 2016

Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.

scientific article

NEMO oligomerization and its ubiquitin-binding properties

scientific article published on 26 June 2009

Preparation of GTPases for structural and biophysical analysis

scientific article published on January 2002

RBR ligase–mediated ubiquitin transfer: a tale with many twists and turns

RNA binding regulates TRIM25-mediated RIG-I ubiquitylation

scientific article published on 05 May 2020

Regulation of NOXO1 activity through reversible interactions with p22 and NOXA1.

scientific article

Reply to "The binding stoichiometry of CIN85 SH3 domain A and Cbl-b".

scientific article

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

scientific article

SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes

scientific article published on 17 August 2016

Sedimentation Equilibrium Studies

Sedimentation equilibrium studies

scientific article published on January 2004

Sequestering of Rac by the Yersinia effector YopO blocks Fcgamma receptor-mediated phagocytosis

scientific article

Single-Domain Antibodies as Crystallization Chaperones to Enable Structure-Based Inhibitor Development for RBR E3 Ubiquitin Ligases

scientific article published on 05 December 2019

Snapshots form a big picture of guanine nucleotide exchange

scientific article published on 6 October 2009

Solution NMR Investigation of the CD95/FADD Homotypic Death Domain Complex Suggests Lack of Engagement of the CD95 C Terminus

scientific article published on 01 October 2010

Structural Analysis of SHARPIN, a Subunit of a Large Multi-protein E3 Ubiquitin Ligase, Reveals a Novel Dimerization Function for the Pleckstrin Homology Superfold

scientific article

Structural Studies of HHARI/UbcH7∼Ub Reveal Unique E2∼Ub Conformational Restriction by RBR RING1.

scientific article

Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding

scientific article

Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP

scientific article

Structural basis for the glycosyltransferase activity of the Salmonella effector SseK3.

scientific article published on 15 February 2018

Structural determinants of TRIM protein function

scientific article published on February 2017

Structure and sites of phosphorylation of 14-3-3 protein: role in coordinating signal transduction pathways.

scientific article published in July 1997

Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue

scientific article

Structure-function analyses of the bacterial zinc metalloprotease effector protein GtgA uncover key residues required for deactivating NF-κB

scientific article published in Journal of Biological Chemistry

Structures of dimeric GIT1 and trimeric beta-PIX and implications for GIT-PIX complex assembly

scientific article

Support for shared ancestry of GAPs

scientific article published in Nature

The Biophysical Characterisation and SAXS Analysis of Human NLRP1 Uncover a New Level of Complexity of NLR Proteins

scientific article

The Structural Basis for 14-3-3:Phosphopeptide Binding Specificity ⬇️

scientific article (publication date: 26 December 1997)

The parkin-coregulated gene product PACRG promotes TNF signaling by stabilizing LUBAC

scientific article published on 04 February 2020

The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways

scientific article

The tandem CARDs of NOD2: intramolecular interactions and recognition of RIP2.

scientific article

Transparency and openness in science

scientific article published on 11 January 2017

pUBLically unzipping Parkin: how phosphorylation exposes a ligase bit by bit.

scientific article published on 7 September 2015

List of works by Katrin Rittinger

Activation and assembly of the NADPH oxidase: a structural perspective

Advanced rules of relays

Architecture of the p40-p47-p67phox complex in the resting state of the NADPH oxidase. A central role for p67phox

Cbl promotes clustering of endocytic adaptor proteins.

Characterisation of class VI TRIM RING domains: linking RING activity to C-terminal domain identity

Conformational stability of dimeric HIV-1 and HIV-2 reverse transcriptases

Control of mitotic exit in budding yeast. In vitro regulation of Tem1 GTPase by Bub2 and Bfa1.

Crucial structural role for the PH and C1 domains of the Vav1 exchange factor

Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP

Crystallization of SHARPIN using an automated two-dimensional grid screen for optimization

Determinants of E2-ubiquitin conjugate recognition by RBR E3 ligases

Determination of the pKa of the N-terminal amino group of ubiquitin by NMR.

Dimerization kinetics of HIV-1 and HIV-2 reverse transcriptase: a two step process

Does it take two to tango? RING domain self-association and activity in TRIM E3 ubiquitin ligases

Editorial overview: Multi-protein assemblies in signaling

Fragment-Based Covalent Ligand Screening Enables Rapid Discovery of Inhibitors for the RBR E3 Ubiquitin Ligase HOIP

Function of the nucleotide exchange activity of vav1 in T cell development and activation

Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity

In Vitro Analysis of Tem1 GTPase Activity and Regulation by the Bfa1/Bub2 GAP.

In silico phosphorylation of the autoinhibited form of p47(phox): insights into the mechanism of activation

Interaction between NOD2 and CARD9 involves the NOD2 NACHT and the linker region between the NOD2 CARDs and NACHT domain

Interactions between Cdc42 and the scaffold protein Scd2: requirement of SH3 domains for GTPase binding

Interface peptides as structure-based human immunodeficiency virus reverse transcriptase inhibitors

Isoform-selective interaction of the adaptor protein Tks5/FISH with Sos1 and dynamins

LUBAC synthesizes linear ubiquitin chains via a thioester intermediate

LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes

Linear ubiquitin chains: enzymes, mechanisms and biology

Linear ubiquitination by LUBEL has a role in Drosophila heat stress response.

Mechanism and function of Vav1 localisation in TCR signalling.

MgF(3)(-) as a transition state analog of phosphoryl transfer

Molecular basis of phosphorylation-induced activation of the NADPH oxidase

Molecular insights into RBR E3 ligase ubiquitin transfer mechanisms

Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.

NEMO oligomerization and its ubiquitin-binding properties

Preparation of GTPases for structural and biophysical analysis

RBR ligase–mediated ubiquitin transfer: a tale with many twists and turns

RNA binding regulates TRIM25-mediated RIG-I ubiquitylation

Regulation of NOXO1 activity through reversible interactions with p22 and NOXA1.

Reply to "The binding stoichiometry of CIN85 SH3 domain A and Cbl-b".

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes

Sedimentation Equilibrium Studies

Sedimentation equilibrium studies

Sequestering of Rac by the Yersinia effector YopO blocks Fcgamma receptor-mediated phagocytosis

Single-Domain Antibodies as Crystallization Chaperones to Enable Structure-Based Inhibitor Development for RBR E3 Ubiquitin Ligases

Snapshots form a big picture of guanine nucleotide exchange

Solution NMR Investigation of the CD95/FADD Homotypic Death Domain Complex Suggests Lack of Engagement of the CD95 C Terminus

Structural Analysis of SHARPIN, a Subunit of a Large Multi-protein E3 Ubiquitin Ligase, Reveals a Novel Dimerization Function for the Pleckstrin Homology Superfold

Structural Studies of HHARI/UbcH7∼Ub Reveal Unique E2∼Ub Conformational Restriction by RBR RING1.

Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding

Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP

Structural basis for the glycosyltransferase activity of the Salmonella effector SseK3.

Structural determinants of TRIM protein function

Structure and sites of phosphorylation of 14-3-3 protein: role in coordinating signal transduction pathways.

Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue

Structure-function analyses of the bacterial zinc metalloprotease effector protein GtgA uncover key residues required for deactivating NF-κB

Structures of dimeric GIT1 and trimeric beta-PIX and implications for GIT-PIX complex assembly

Support for shared ancestry of GAPs

The Biophysical Characterisation and SAXS Analysis of Human NLRP1 Uncover a New Level of Complexity of NLR Proteins

The Structural Basis for 14-3-3:Phosphopeptide Binding Specificity ⬇️

The parkin-coregulated gene product PACRG promotes TNF signaling by stabilizing LUBAC

The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways

The tandem CARDs of NOD2: intramolecular interactions and recognition of RIP2.

Transparency and openness in science

pUBLically unzipping Parkin: how phosphorylation exposes a ligase bit by bit.