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List of works by Joanna I. Loizou

A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN.

scientific article

ATMIN is required for maintenance of genomic stability and suppression of B cell lymphoma

scientific article published on May 2011

ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress.

scientific article published on 26 September 2014

CDK6 Antagonizes p53-Induced Responses during Tumorigenesis

article

Competition between NBS1 and ATMIN controls ATM signaling pathway choice

scientific article published on 6 December 2012

DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation

scientific article

DNA replication stress: causes, resolution and disease

scientific article

Genome-scale CRISPR screens are efficient in non-homologous end-joining deficient cells

scientific article published on 31 October 2019

High activation of STAT5A drives peripheral T-cell lymphoma and leukemia

scientific article published on 31 January 2020

Histone Acetyltransferase Cofactor Trrap Is Essential for Maintaining the Hematopoietic Stem/Progenitor Cell Pool

scientific article published on 30 October 2009

Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

scientific article

Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis

scientific article published on 15 July 2019

Interference of papillomavirus E6 protein with single-strand break repair by interaction with XRCC1.

scientific article

MEK inhibitors block growth of lung tumours with mutations in ataxia-telangiectasia mutated.

scientific article published on 6 December 2016

Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48.

scientific article published on 11 June 2018

Mapping the Human Kinome in Response to DNA Damage

scientific article published on 01 January 2019

Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia

scientific article published in November 2017

Perturbed hematopoiesis in mice lacking ATMIN.

scientific article published on 31 August 2016

Polymerase δ deficiency causes syndromic immunodeficiency with replicative stress

scientific article published on 01 October 2019

Prime editing efficiency and fidelity are enhanced in the absence of mismatch repair

scientific article published in 2022

Programmed DNA breaks in lymphoid cells: repair mechanisms and consequences in human disease

scientific article published on 12 October 2015

Repair of UV-Induced DNA Damage Independent of Nucleotide Excision Repair Is Masked by MUTYH.

scientific article published in November 2017

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

scientific article

Synthetic Lethal Interactions for Kinase Deficiencies to DNA Damage Chemotherapeutics

scientific article published on 06 August 2019

The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks

scientific article

Validating the concept of mutational signatures with isogenic cell models.

scientific article published in May 2018

enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities

scientific article published on 11 February 2019