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List of works by Jane Skok

4C-ker: A Method to Reproducibly Identify Genome-Wide Interactions Captured by 4C-Seq Experiments

scientific article

A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination

scientific article published on 15 June 2016

A multifunctional element in the mouse Igκ locus that specifies repertoire and Ig loci subnuclear location.

scientific article

A new take on v(d)j recombination: transcription driven nuclear and chromatin reorganization in rag-mediated cleavage.

scientific article published on 06 December 2013

Active and Inactive Enhancers Cooperate to Exert Localized and Long-Range Control of Gene Regulation.

scientific article published on 25 May 2016

Analysis of 3D genomic interactions identifies candidate host genes that transposable elements potentially regulate

article

Association between the Igk and Igh immunoglobulin loci mediated by the 3' Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells

scientific article published on 24 February 2008

B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage

scientific article published on 18 October 2019

Breaking TADs: insights into hierarchical genome organization.

scientific article published on June 2015

C-terminal SRC kinase controls acute inflammation and granulocyte adhesion

scientific article published in February 2004

CRISPR-dCas9 and sgRNA scaffolds enable dual-colour live imaging of satellite sequences and repeat-enriched individual loci.

scientific article

CTCF and CTCFL in cancer

scientific article published on 22 April 2020

CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation

scientific article published on February 2015

Capturing the Onset of PRC2-Mediated Repressive Domain Formation

scientific article published on 01 June 2018

Close proximity to Igh is a contributing factor to AID-mediated translocations.

scientific article published on 2 August 2012

Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms

scientific article

Control of B-1a cell development by instructive BCR signaling

scientific article published on 3 February 2018

DNA methylation disruption reshapes the hematopoietic differentiation landscape

scientific article published on 23 March 2020

Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation

scientific article published on 11 May 2020

Dendritic cell-derived IL-12 promotes B cell induction of Th2 differentiation: a feedback regulation of Th1 development

article

Dynamic changes in accessibility, nuclear positioning, recombination, and transcription at the Ig kappa locus.

scientific article

Enhancer talk

scientific article published on 27 March 2018

EpiMethylTag: simultaneous detection of ATAC-seq or ChIP-seq signals with DNA methylation

scientific article published on 21 November 2019

Epigenetic ontogeny of the Igk locus during B cell development

scientific article published on 26 December 2004

Equal opportunity for all.

scientific article published on 13 March 2012

Erratum: Corrigendum: RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

scholarly article published in Nature Immunology

Erratum: Corrigendum: RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

scholarly article published in Nature Immunology

IL-7 functionally segregates the pro-B cell stage by regulating transcription of recombination mediators across cell cycle

scientific article published on 11 May 2012

Identification of multi-loci hubs from 4C-seq demonstrates the functional importance of simultaneous interactions.

scientific article published on 20 July 2016

Impaired Expression of Rearranged Immunoglobulin Genes and Premature p53 Activation Block B Cell Development in BMI1 Null Mice

scientific article published on 01 January 2019

Interpreting 4C-Seq data: how far can we go?

scientific article

It takes two: communication between homologous alleles preserves genomic stability during V(D)J recombination.

scientific article published on January 2010

Jane Skok: choreography of allelic exclusion. [Interview by Hema Bashyam].

scientific article published on July 2008

Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene

scientific article published on 05 December 2004

Long-Range Regulation of V(D)J Recombination

scientific article

Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2.

scientific article published in October 2017

MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis

scientific article published on 24 August 2016

Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination

scientific article published on 22 February 2016

Molecular biology. Finding the right partner in a 3D genome.

scientific article published on December 2013

NSD2 overexpression drives clustered chromatin and transcriptional changes in a subset of insulated domains

scientific article published on 24 October 2019

Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes.

scientific article

Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2+ Breast Cancer

scientific article published in 2021

Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene

scientific article published on February 2004

RAG Off-Target Activity Is in the Loop

scientific article published on 18 November 2015

RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

scientific journal article

RNA Interactions Are Essential for CTCF-Mediated Genome Organization

scientific article published on 12 September 2019

Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling.

scientific article

Response to Casellas et al

scientific article published on August 2013

Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes

scientific article published on 04 March 2007

Rewiring of CD40 is necessary for delivery of rescue signals to B cells in germinal centres and subsequent entry into the memory pool.

scientific article

Scaffold association factor B (SAFB) is required for expression of prenyltransferases and RAS membrane association

scientific article published on 30 November 2020

Silencing and nuclear repositioning of the lambda5 gene locus at the pre-B cell stage requires Aiolos and OBF-1.

scientific article

Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development

scientific article published in Nature Communications

Taking a break from the lab: can it really be done?

scientific article published on 24 November 2014

The Conserved ATM Kinase RAG2-S365 Phosphorylation Site Limits Cleavage Events in Individual Cells Independent of Any Repair Defect

scientific article published on October 2017

The Ig heavy chain protein but not its message controls early B cell development

scientific article published on 23 November 2020

The IgH locus 3' cis-regulatory super-enhancer co-opts AID for allelic transvection

scientific article published on 10 January 2017

The RAG2 C terminus suppresses genomic instability and lymphomagenesis ⬇️

scientific article published on March 3, 2011

The novel lncRNA BlackMamba controls the neoplastic phenotype of ALK- anaplastic large cell lymphoma by regulating the DNA helicase HELLS

scientific article published on 02 March 2020

The origin of recurrent translocations in recombining lymphocytes: a balance between break frequency and nuclear proximity.

scientific article published on 13 March 2013

The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription.

scientific article

The role of CTCF in regulating V(D)J recombination

scientific article

V(D)J recombination: a paradigm for studying chromosome interactions in mammalian cells

scientific article published on 01 April 2010

VH replacement in primary immunoglobulin repertoire diversification.

scientific article

Wolf-Hirschhorn Syndrome Candidate 1 Is Necessary for Correct Hematopoietic and B Cell Development

scientific article published in May 2017

Yin Yang 1 is a critical regulator of B-cell development

scientific article published on May 2007

miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation

scientific article

β-Catenin induces T-cell transformation by promoting genomic instability

scientific article published on 26 December 2013

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