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List of works by Gabriela Riemekasten

2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative

scientific article

2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative

scientific article

A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations

scientific article published on 10 November 2011

A gender gap in primary and secondary heart dysfunctions in systemic sclerosis: a EUSTAR prospective study

scientific article published on 23 October 2014

A genome-wide association study follow-up suggests a possible role for PPARG in systemic sclerosis susceptibility

scientific article published on 09 January 2014

A large multicentre analysis of CTGF -945 promoter polymorphism does not confirm association with systemic sclerosis susceptibility or phenotype

scientific article published on 03 December 2008

A rare polymorphism in the gene for Toll-like receptor 2 is associated with systemic sclerosis phenotype and increases the production of inflammatory mediators

article

A regulatory variant in CCR6 is associated with susceptibility to antitopoisomerase-positive systemic sclerosis

scientific article published on December 2013

A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort

scientific article published on 27 December 2010

A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci

scientific article published on 04 June 2013

An EULAR study group pilot study on reliability of simple capillaroscopic definitions to describe capillary morphology in rheumatic diseases

scientific article

An MIF Promoter Polymorphism Is Associated with Susceptibility to Pulmonary Arterial Hypertension in Diffuse Cutaneous Systemic Sclerosis.

scientific article

Analysis of ATP8B4 F436L Missense Variant in a Large Systemic Sclerosis Cohort

scientific article published on 09 May 2017

Analysis of the association between CD40 and CD40 ligand polymorphisms and systemic sclerosis.

scientific article

Analysis of the influence of PTPN22 gene polymorphisms in systemic sclerosis

scientific article

Angiotensin II type 1 receptor antibodies and increased angiotensin II sensitivity in pregnant rats

scientific article published on 16 May 2011

Angiotensin receptor type 1 and endothelin receptor type A on immune cells mediate migration and the expression of IL-8 and CCL18 when stimulated by autoantibodies from systemic sclerosis patients

scientific article

Antibodies against PM/Scl-75 and PM/Scl-100 are independent markers for different subsets of systemic sclerosis patients

scientific article published on 16 February 2009

Antibodies to Signaling Molecules and Receptors in Alzheimer's Disease are Associated with Psychomotor Slowing, Depression, and Poor Visuospatial Function

scientific article

Anticentromere-A and Anticentromere-B Antibodies Show High Concordance and Similar Clinical Associations in Patients with Systemic Sclerosis ⬇️

scientific article published on October 1, 2010

Apoptotic marginal zone deletion of anti-Sm/ribonucleoprotein B cells

scientific article

Are interferon-related biomarkers advantageous for monitoring disease activity in systemic lupus erythematosus? A longitudinal benchmark study

scientific article published in September 2017

Are we too lenient with immunosuppression in severe cases of Systemic Sclerosis?

scientific article published on 21 June 2016

Association between baseline clinical and imaging findings and the development of digital ulcers in patients with systemic sclerosis

article

Association of a non-synonymous functional variant of the ITGAM gene with systemic sclerosis

article

Association of the CD226 Ser(307) variant with systemic sclerosis: evidence of a contribution of costimulation pathways in systemic sclerosis pathogenesis

scientific article published in April 2011

Association of the TNFAIP3 rs5029939 variant with systemic sclerosis in the European Caucasian population

article published in 2010

Autoantibodies against Endothelin 1 Type A Receptor Are Strong Predictors of Digital Ulcers in Systemic Sclerosis

scientific article published on August 2015

Autoantibodies in Serum of Systemic Scleroderma Patients: Peptide-Based Epitope Mapping Indicates Increased Binding to Cytoplasmic Domains of CXCR3.

scientific article published on 22 March 2018

Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity

scientific article published on 09 March 2022

Autoantibodies to angiotensin and endothelin receptors in systemic sclerosis induce cellular and systemic events associated with disease pathogenesis

scientific article published on 28 January 2014

B Cells Are Indispensable for a Novel Mouse Model of Primary Sjögren's Syndrome

scientific article published on 24 October 2017

BANK1 functional variants are associated with susceptibility to diffuse systemic sclerosis in Caucasians

scientific article published on 8 October 2009

Beta-1-Adrenergic Receptor Antibodies in Acute Coronary Syndrome: Is Less Sometimes More?

article by Diana Ernst et al published 2018 in Frontiers in cardiovascular medicine

Bronchoalveoloar lavage fluid cytokines and chemokines as markers and predictors for the outcome of interstitial lung disease in systemic sclerosis patients

scientific article published on 17 July 2009

CD4+Foxp3+ regulatory T cells prolong drug-induced disease remission in (NZBxNZW) F1 lupus mice ⬇️

scientific article published on February 27, 2013

CD40 ligand deficiency causes functional defects of peripheral neutrophils that are improved by exogenous IFN-γ.

scientific article published on 5 March 2018

CXCR3+CD4+ T cells are enriched in inflamed kidneys and urine and provide a new biomarker for acute nephritis flares in systemic lupus erythematosus patients

scientific article published on January 2009

Casein is an essential cofactor in autoantibody reactivity directed against the C-terminal SmD1 peptide AA 83-119 in systemic lupus erythematosus

scientific article published in December 2002

Characterization of kidney infiltrating T cells in the NZB/W F1 lupus model.

scientific article published on 24 February 2004

Class switching and consecutive loss of dsDNA-reactive B1a B cells from the peritoneal cavity during murine lupus development

scientific article published in June 2010

Classification, categorization and essential items for digital ulcer evaluation in systemic sclerosis: a DeSScipher/European Scleroderma Trials and Research group (EUSTAR) survey

scientific article

Clinical and serological evaluation of a novel CENP-A peptide based ELISA

scientific article (publication date: 2010)

Clinical determinants of elevated systolic pulmonary artery pressure measured by transthoracic Doppler echocardiography in early systemic sclerosis.

scientific article

Clinical prediction of 5-year survival in systemic sclerosis: validation of a simple prognostic model in EUSTAR centres

scientific article

Clinical trials: The rise of IL-2 therapy - a novel biologic treatment for SLE.

scientific article

Common German language nomenclature for systemic sclerosis

scientific article published in March 2015

Comparison of patients with and without digital ulcers in systemic sclerosis: detection of possible risk factors

scientific article published on 13 January 2009

Computational analysis of high-density peptide microarray data with application from systemic sclerosis to multiple sclerosis

scientific article

Confirmation of CCR6 as a risk factor for anti-topoisomerase I antibodies in systemic sclerosis.

scientific article published on 27 August 2015

Confirmation of association of the macrophage migration inhibitory factor gene with systemic sclerosis in a large European population

article

Correction: Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy.

scientific article published on 25 August 2011

Correction: Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy.

scientific article

Critical limb ischemia in systemic sclerosis ⬇️

scientific article published on June 1, 2012

Cytokine imbalance in NZB/W mice is associated with autoantibody levels and nephritis.

scientific article published on 24 February 2004

Detection of severe digital vasculopathy in systemic sclerosis by colour Doppler sonography is associated with digital ulcers

scientific article published on 17 March 2017

Diagnostic value of anti-topoisomerase I antibodies in a large monocentric cohort

scientific article published on 21 February 2009

Digital ulcers predict a worse disease course in patients with systemic sclerosis

scientific article published on 16 February 2015

Digital ulcers score: a scoring system to assess digital ulcers in patients suffering from systemic sclerosis

scientific article published on September 2016

Disability, fatigue, pain and their associates in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study ⬇️

scientific article

Disease progression in systemic sclerosis-overlap syndrome is significantly different from limited and diffuse cutaneous systemic sclerosis

scientific article

Disturbed microcirculation in the hands of patients with systemic sclerosis detected by fluorescence optical imaging: a pilot study

scientific article

Dysregulated homeostasis of target tissues or autoantigens - A novel principle in autoimmunity

scientific article

E-learning program from the German Society of Rheumatology

scientific article published on 30 May 2016

EUSTAR biobanking: recommendations for the collection, storage and distribution of biospecimens in scleroderma research

scientific article published in February 2011

Early right ventricular systolic dysfunction in patients with systemic sclerosis without pulmonary hypertension: a Doppler Tissue and Speckle Tracking echocardiography study

scientific article

Echocardiographic follow-up of patients with systemic sclerosis by 2D speckle tracking echocardiography of the left ventricle

scientific article published on 29 March 2014

Effect of biofeedback and deep oscillation on Raynaud's phenomenon secondary to systemic sclerosis: results of a controlled prospective randomized clinical trial

scientific article published on 8 April 2011

Effect of sildenafil on digital ulcers in systemic sclerosis: analysis from a single centre pilot study

scientific article

Efficacy and Safety of Selexipag in Adults With Raynaud's Phenomenon Secondary to Systemic Sclerosis: A Randomized, Placebo-Controlled, Phase II Study

scientific article published in December 2017

Elevated serum levels of sonic hedgehog are associated with fibrotic and vascular manifestations in systemic sclerosis.

scientific article published on 11 May 2017

Enhanced serum prolactin (PRL) in patients with systemic lupus erythematosus: PRL levels are related to the disease activity

scientific article published on January 2001

Environmental factor and inflammation-driven alteration of the total peripheral T-cell compartment in granulomatosis with polyangiitis

scientific article

Erectile dysfunction is frequent in systemic sclerosis and associated with severe disease: a study of the EULAR Scleroderma Trial and Research group

scientific article

Erratum: Corrigendum: Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus

scholarly article published in Nature Genetics

Evidence of the contribution of the X chromosome to systemic sclerosis susceptibility: association with the functional IRAK1 196Phe/532Ser haplotype.

scientific article published in December 2011

Familiality and co-occurrence of clinical features of systemic lupus erythematosus

scientific article

Frequency of disease-associated and other nuclear autoantibodies in patients of the German Network for Systemic Scleroderma: correlation with characteristic clinical features

scientific article published on 21 October 2011

Functional Variants of Fc Gamma Receptor (FCGR2A) and FCGR3A Are Not Associated with Susceptibility to Systemic Sclerosis in a Large European Study (EUSTAR)

scientific article published on 15 June 2010

Functional autoantibodies in systemic sclerosis pathogenesis

scientific article

Functional autoantibodies targeting G protein-coupled receptors in rheumatic diseases

scientific article published on 31 August 2017

GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis

scientific article published in Nature Communications

Gender differences in early systemic sclerosis patients: a report from the EULAR scleroderma trials and research group (EUSTAR) database

Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus

scientific article

Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis

scientific article

Heme oxygenase-1 promoter polymorphisms do not influence susceptibility to systemic sclerosis and its clinical phenotypes.

scientific article published on 7 February 2013

High frequency of corticosteroid and immunosuppressive therapy in patients with systemic sclerosis despite limited evidence for efficacy

scientific article

Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus

scientific article

IFNα and its response proteins, IP-10 and SIGLEC-1, are biomarkers of disease activity in systemic lupus erythematosus

scientific article

Identification and characterization of SmD183-119-reactive T cells that provide T cell help for pathogenic anti-double-stranded DNA antibodies

scientific article published on February 2003

Identification of CSK as a systemic sclerosis genetic risk factor through Genome Wide Association Study follow-up

scientific article

Identification of IL12RB1 as a novel systemic sclerosis susceptibility locus

scientific article

Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy

scientific article

Identification of novel genetic markers associated with the clinical phenotypes of systemic sclerosis through a genome wide association strategy

scientific article published on 25 November 2010

Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis

scientific article published on January 2014

Immunology and the diagnosis of lupus nephritis

scientific article published in April 2009

Implication of IL-2/IL-21 region in systemic sclerosis genetic susceptibility

scientific article

In vitro and in vivo activation induces BAFF and APRIL expression in B cells

scientific article published in November 2007

Incidence and predictors of cutaneous manifestations during the early course of systemic sclerosis: a 10-year longitudinal study from the EUSTAR database

scientific article published on 31 July 2015

Incidences and Risk Factors of Organ Manifestations in the Early Course of Systemic Sclerosis: A Longitudinal EUSTAR Study ⬇️

scientific article

Increased Periodontal Attachment Loss in Patients With Systemic Sclerosis

scientific article

Induction of Hypergammaglobulinemia and Autoantibodies by Salmonella Infection in MyD88-Deficient Mice.

scientific article published on 20 June 2018

Induction of pathogenic anti-dsDNA antibodies is controlled on the level of B cells in a non-lupus prone mouse strain

scientific article published in January 2006

Influence of TYK2 in systemic sclerosis susceptibility: a new locus in the IL-12 pathway.

scientific article published on 2 September 2015

Influence of bosentan on fingertip rewarming in patients with systemic sclerosis

scientific article

Influence of the IL6 gene in susceptibility to systemic sclerosis

scientific article

Interstitial lung disease increases mortality in systemic sclerosis patients with pulmonary arterial hypertension without affecting hemodynamics and exercise capacity

scientific article published on 27 December 2016

Intravenous injection of a D1 protein of the Smith proteins postpones murine lupus and induces type 1 regulatory T cells

scientific article published in November 2004

Intrinsic Deregulation of Vascular Smooth Muscle and Myofibroblast Differentiation in Mesenchymal Stromal Cells from Patients with Systemic Sclerosis

scientific article

Involvement of functional autoantibodies against vascular receptors in systemic sclerosis

scientific article published on 15 November 2010

Is there a role for TNFα antagonists in the treatment of SSc? EUSTAR expert consensus development using the Delphi technique

scientific article published in March 2011

Items for developing revised classification criteria in systemic sclerosis: Results of a consensus exercise

scientific article published on March 2012

Joint and tendon involvement predict disease progression in systemic sclerosis: a EUSTAR prospective study

scientific article published on 27 August 2014

Lack of association between three vascular endothelial growth factor gene polymorphisms and systemic sclerosis: results from a multicenter EUSTAR study of European Caucasian patients

scientific article published on June 2006

Long-term effects of bosentan on quality of life, survival, safety and tolerability in pulmonary arterial hypertension related to connective tissue diseases

scientific article published on 30 November 2007

Low versus high-dose iloprost therapy over 21 days in patients with secondary Raynaud's phenomenon and systemic sclerosis: a randomized, open, single-center study

scientific article

Low-dose IL-2 therapy - a complex scenario that remains to be further explored

scientific article published on 11 May 2017

Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus

scientific article published on 31 August 2015

Management of cutaneous vascular complications in systemic scleroderma: experience from the German network

scientific article

Management of digital ulcers in patients with systemic sclerosis

scientific article published on 16 December 2011

Mapping and predicting mortality from systemic sclerosis

scientific article

Mapping urinary chemokines in human lupus nephritis: Potentially redundant pathways recruit CD4+ and CD8+ T cells and macrophages

scientific article published on 18 October 2016

Medicinal vasoactive therapy of microcirculation disorders in rheumatoid arthritis

scientific article published in March 2005

Multicriteria decision analysis methods with 1000Minds for developing systemic sclerosis classification criteria

scientific article

NLRP1 influences the systemic sclerosis phenotype: a new clue for the contribution of innate immunity in systemic sclerosis-related fibrosing alveolitis pathogenesis

Natural Treg and role of IL-2 in lupus.

scientific article

New insight on the Xq28 association with systemic sclerosis

scientific article published on 26 February 2013

Non organ based laboratory markers in systemic sclerosis

scientific article

Non-invasive diagnosis of pulmonary hypertension: ESC/ERS Guidelines with Updated Commentary of the Cologne Consensus Conference 2011.

scientific article published on December 2011

Novelties in the field of autoimmunity - 1st Saint Petersburg congress of autoimmunity, the bridge between east and west

scientific article

Nutritional status as marker for disease activity and severity predicting mortality in patients with systemic sclerosis

scientific article published on 28 May 2010

OP0059 Phenotypes Determined by Cluster Analysis and their Survival in the Prospective Eustar Cohort of Patients with Systemic Sclerosis

Osteopontin in the development of systemic sclerosis--relation to disease activity and organ manifestation

article

Pathogenetic and Clinical Aspects of Anti-Neutrophil Cytoplasmic Autoantibody-Associated Vasculitides

scientific article published on 9 April 2018

Patient acceptable symptom state in scleroderma: results from the tocilizumab compared with placebo trial in active diffuse cutaneous systemic sclerosis

scientific article published on 25 October 2017

Persistence of plasma cells in the kidneys of autoimmune NZB/W mice.

scientific article published on 26 January 2001

Polymorphisms in the interleukin 4, interleukin 13 and corresponding receptor genes are not associated with Systemic Sclerosis and do not influence gene expression.

scientific article

Polymorphisms in the interleukin 4, interleukin 13, and corresponding receptor genes are not associated with systemic sclerosis and do not influence gene expression

scientific article

Prevalence and factors associated with left ventricular dysfunction in the EULAR Scleroderma Trial and Research group (EUSTAR) database of patients with systemic sclerosis

scientific article

Randomized, prospective, placebo-controlled trial of bosentan in interstitial lung disease secondary to systemic sclerosis

scientific article published in July 2010

Rapid induction of clinical remission by low-dose interleukin-2 in a patient with refractory SLE.

scientific article published on 21 January 2015

Raynaud phenomenon in dermatology : Part 2: therapy

scientific article published in October 2006

Raynaud phenomenon in dermatology. Part 1: Pathophysiology and diagnostic approach

scientific article published in September 2006

Reply: vascular receptor autoantibodies in pulmonary arterial hypertension

scientific article published in March 2015

Responders to cyclophosphamide: results of a single-centre analysis among systemic sclerosis patients

scientific article published on 11 June 2012

Restoring regulation - IL-2 therapy in systemic lupus erythematosus

scientific article

Riociguat for the treatment of pulmonary arterial hypertension associated with connective tissue disease: results from PATENT-1 and PATENT-2.

scientific article published on 25 July 2016

Risk factors for severity and manifestations in systemic sclerosis and prediction of disease course

scientific article

Safety and efficacy of subcutaneous tocilizumab in adults with systemic sclerosis (faSScinate): a phase 2, randomised, controlled trial

scientific article published on 5 May 2016

Scleroderma Renal Crisis: Risk Factors for an Increasingly Rare Organ Complication

scientific article published on 01 April 2019

Six-minute walk distance as a marker for disability and complaints in patients with systemic sclerosis

scientific article published on March 1, 2011

Skin sclerosis is only of limited value to identify SSc patients with severe manifestations--an analysis of a distinct patient subgroup of the German Systemic Sclerosis Network (DNSS) Register

scientific article published on January 2009

Stem-cell transplantation in systemic sclerosis?--Cardiac health is decisive for the patient's benefit ⬇️

scientific article published on May 15, 2013

Submaximal exercise testing in the assessment of interstitial lung disease secondary to systemic sclerosis: reproducibility and correlations of the 6-min walk test

scientific article published on 25 July 2006

Subset size, activation threshold and distribution of autoreactive MZ and FO B cells do not differ in a sex-specific manner in the NZB/W F1 murine lupus model: An experimental mouse study ⬇️

scientific article published on August 15, 2011

Systemic activation of the immune system induces aberrant BAFF and APRIL expression in B cells in patients with systemic lupus erythematosus

scientific article published in July 2009

Systemic sclerosis associated interstitial lung disease - individualized immunosuppressive therapy and course of lung function: results of the EUSTAR group

scientific article published on 30 January 2018

TGFβ receptor gene variants in systemic sclerosis-related pulmonary arterial hypertension: results from a multicentre EUSTAR study of European Caucasian patients

article

Targeting activated T cells: successful use of anti-CD25 monoclonal antibody basiliximab in a patient with systemic sclerosis

scientific article published on September 2006

The -2518A>G promoter polymorphism in the CCL2 gene is not associated with systemic sclerosis susceptibility or phenotype: results from a multicenter study of European Caucasian patients

article

The EUSTAR model for teaching and implementing the modified Rodnan skin score in systemic sclerosis

scientific article published on 18 January 2007

The Effects of Antigen-Specific IgG1 Antibody for the Pulmonary-Hypertension-Phenotype and B Cells for Inflammation in Mice Exposed to Antigen and Fine Particles from Air Pollution

scientific article published on 16 June 2015

The European Scleroderma Trials and Research group (EUSTAR) task force for the development of revised activity criteria for systemic sclerosis: derivation and validation of a preliminarily revised EUSTAR activity index

scientific article published on 12 September 2016

The Predict Study: low risk for digital ulcer development in patients with systemic sclerosis with increasing disease duration and lack of topoisomerase-1 antibodies

scientific article published on 26 December 2015

The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype

scientific article published on 13 March 2009

The cellular signature of urinary immune cells in Lupus nephritis: new insights into potential biomarkers

scientific article published on 3 April 2015

The functional polymorphism 844 A>G in FcαRI (CD89) does not contribute to systemic sclerosis or rheumatoid arthritis susceptibility

scientific article published on 15 December 2010

The impact of malnutrition on quality of life in patients with systemic sclerosis

scientific article published on 8 March 2018

The status of pulmonary fibrosis in systemic sclerosis is associated with IRF5, STAT4, IRAK1, and CTGF polymorphisms.

scientific article published on 22 April 2017

The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis.

scientific article

Therapie der pulmonal arteriellen Hypertonie (PAH)

There is a need for new systemic sclerosis subset criteria. A content analytic approach.

scientific article published on 9 October 2017

Towards an implementation of guidelines for the therapy of systemic sclerosis (scleroderma): between desire and reality

scientific article published in June 2010

Treatment of pulmonary arterial hypertension (PAH): updated Recommendations of the Cologne Consensus Conference 2011

scientific article

Treatment outcome in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study (ESOS). ⬇️

scientific article published on 10 February 2017

Two-dimensional speckle tracking of the left ventricle in patients with systemic sclerosis for an early detection of myocardial involvement ⬇️

scientific article published on March 16, 2012

Type 1 regulatory T cells in treatment of murine lupus.

scientific article published on 17 February 2005

Unmasking of autoreactive CD4 T cells by depletion of CD25 regulatory T cells in systemic lupus erythematosus

scientific article published on 16 September 2011

Update of EULAR recommendations for the treatment of systemic sclerosis

scientific article published on 9 November 2016

Update on the profile of the EUSTAR cohort: an analysis of the EULAR Scleroderma Trials and Research group database

scientific article

Urinary CD4 T cells identify SLE patients with proliferative lupus nephritis and can be used to monitor treatment response

scientific article

Validation of potential classification criteria for systemic sclerosis

scientific article

Value of systolic pulmonary arterial pressure as a prognostic factor of death in the systemic sclerosis EUSTAR population

scientific article published on 17 January 2015

Variants of PBEF predispose to systemic sclerosis and pulmonary arterial hypertension development.

scientific article

Vascular hypothesis revisited: Role of stimulating antibodies against angiotensin and endothelin receptors in the pathogenesis of systemic sclerosis

scientific article published on 9 March 2016

Vasoactive Therapy in Systemic Sclerosis: Real-life Therapeutic Practice in More Than 3000 Patients

scientific article published on 15 November 2015

[Granulomatosis with polyangiitis]

scientific article published on 05 January 2017

[Standards of care for people with rheumatoid arthritis in Europe : Translation and comments of the eumusc.net recommendations supported by EULAR performed by a national task force of the professional organisations DGRh and VRA supported by "Deutsch

scientific article published on 2 May 2016

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