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List of works by Doris Koesling

AMPA Induces NO-Dependent cGMP Signals in Hippocampal and Cortical Neurons via L-Type Voltage-Gated Calcium Channels

scientific article published on 11 November 2019

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017

article

Activation of PDE10 and PDE11 Phosphodiesterases ⬇️

scientific article published on November 21, 2011

Activation of PDE10 and PDE11.

scientific article published in August 2011

Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5.

scientific article published on December 2010

Angiotensin II-Induced Hypertension Is Attenuated by Reduction of Sympathetic Output in NO-Sensitive Guanylyl Cyclase 1 Knockout Mice.

scientific article published on 11 November 2015

Bioactivation of nitroglycerin by ascorbate

scientific article published on 19 April 2007

Bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases

scientific article published on May 2008

Bioactivation of nitroglycerin by the East Asian variant of aldehyde dehydrogenase-2

Bioactivation of nitroglycerin by the East Asian variant of aldehyde dehydrogenase-2.

scientific article published on 12 November 2009

Bioactivation of pentaerythrityl tetranitrate by mitochondrial aldehyde dehydrogenase.

scientific article published on 14 December 2010

Bioactivation of pentaerythrityl tetranitrate by mitochondrial aldehyde dehydrogenase.

scientific article published on 11 August 2009

C-type natriuretic peptide (CNP) is a bifurcation factor for sensory neurons.

scientific article published on 17 September 2009

C-type natriuretic peptide is a bifurcation factor for sensory neurons

scientific article published on 11 August 2009

Characterization of the East Asian variant of aldehyde dehydrogenase-2: bioactivation of nitroglycerin and effects of Alda-1.

scientific article published on 11 November 2009

Comparative analysis of PDE10A isoforms.

scientific article published in August 2011

Contribution of aldehyde dehydrogenase to mitochondrial bioactivation of nitroglycerin: evidence for the activation of purified soluble guanylate cyclase through direct formation of nitric oxide.

scientific article published on February 2005

Contribution of the NO-GC isoforms to airway responsiveness.

scientific article

Crystal structure of the GAF-B domain from human phosphodiesterase 5

scientific article

Cyclic GMP in Vascular Relaxation: Export Is of Similar Importance as Degradation.

scientific article published on 23 July 2015

Desensitization of NO/cGMP signaling in smooth muscle: blood vessels versus airways

scientific article published in March 2006

Design of fluorescence resonance energy transfer (FRET)-based cGMP indicators: a systematic approach

scientific article published on October 2007

Differential role of NO-sensitive guanylyl cyclase isoforms NO-GC1 and NO-GC2 in auditory function in adult mice.

scientific article

Dimerization of nitric oxide-sensitive guanylyl cyclase requires the alpha 1 N terminus.

scientific article published on 3 March 2005

Direct activation of PDE5 by cGMP: long-term effects within NO/cGMP signaling

scientific article

Distinct functions of soluble guanylyl cyclase isoforms NO-GC1 and NO-GC2 in inflammatory and neuropathic pain processing

scientific article published on 01 March 2019

Does a reduction of vascular relaxation promote hypertension?

scientific article published in August 2011

Dual acylation of PDE2A splice variant 3: targeting to synaptic membranes

scientific journal article

Dysfunctional nitric oxide signalling increases risk of myocardial infarction

scientific article published on 10 November 2013

Effects of flavoring compounds used in electronic cigarette refill liquids on endothelial and vascular function

scientific article published on 09 September 2019

Effects of nitroglycerin/L-cysteine on soluble guanylate cyclase: evidence for an activation/inactivation equilibrium controlled by nitric oxide binding and haem oxidation.

scientific article published on September 2005

Evaluation of ODQ as specific inhibitor of NO-sensitive guanylyl cyclase using mice deficient for the enzyme

scientific article published on 11 August 2009

Exogenous nitric oxide donation causes desensitization of arteriolar relaxing activity in vivo: an intravital analysis in mice

scientific article published on 5 August 2009

Fatal gastrointestinal obstruction and hypertension in mice lacking nitric oxide-sensitive guanylyl cyclase

scholarly article

Formation of Nitric Oxide by Aldehyde Dehydrogenase-2 Is Necessary and Sufficient for Vascular Bioactivation of Nitroglycerin.

scientific article published on 27 September 2016

Functions of NO-GC1 and NO-GC2 in pain processing.

scientific article

GAF domain-induced activation of phosphodiesterases 2 and 5

Genetic mouse models of the NO receptor 'soluble' guanylyl cyclases

scientific article published on January 2009

Guanylyl cyclase: NO hits its target.

scientific article

Identification of a soluble guanylate cyclase in RBCs: preserved activity in patients with coronary artery disease

scientific article

Impact of the NO-Sensitive Guanylyl Cyclase 1 and 2 on Renal Blood Flow and Systemic Blood Pressure in Mice.

scientific article published on 23 March 2018

In striatum phosphodiesterase 10A is part of a synaptic signalling complex.

scientific article published on 29 August 2013

In vivo reconstitution of the negative feedback in nitric oxide/cGMP signaling: role of phosphodiesterase type 5 phosphorylation

scientific article

Inactivation of soluble guanylate cyclase by stoichiometric S-nitrosation

scientific article

Inhibition of deactivation of NO-sensitive guanylyl cyclase accounts for the sensitizing effect of YC-1.

scientific article published on 26 April 2002

Inhibition of phosphodiesterase type 5 by the activator of nitric oxide-sensitive guanylyl cyclase BAY 41-2272.

scientific article published on 5 April 2004

Irreversible activation and stabilization of soluble guanylate cyclase by the protoporphyrin IX mimetic cinaciguat.

scientific article

Isoforms of NO-sensitive guanylyl cyclase

scientific article

Long-term potentiation in the visual cortex requires both nitric oxide receptor guanylyl cyclases.

scientific article

Major occurrence of the new alpha2beta1 isoform of NO-sensitive guanylyl cyclase in brain

scientific article published on February 2003

Measurement of cGMP-generating and -degrading activities and cGMP levels in cells and tissues: Focus on FRET-based cGMP indicators

scientific article published on 21 April 2018

Mechanisms underlying activation of soluble guanylate cyclase by the nitroxyl donor Angeli's salt

scientific article published on 31 August 2009

Mind the gap (junction): cGMP induced by nitric oxide in cardiac myocytes originates from cardiac fibroblasts

scientific article published on 27 December 2019

Mitochondrial nitrite reduction coupled to soluble guanylate cyclase activation: lack of evidence for a role in the bioactivation of nitroglycerin.

scientific article published on 5 October 2008

Modulation of Hyperpolarization-Activated Inward Current and Thalamic Activity Modes by Different Cyclic Nucleotides

scientific article published on 24 October 2018

Modulation of nitric oxide-stimulated soluble guanylyl cyclase activity by cytoskeleton-associated proteins in vascular smooth muscle

scientific article published on 10 August 2018

More than a retrograde messenger: nitric oxide needs two cGMP pathways to induce hippocampal long-term potentiation.

scientific article

NO activation of guanylyl cyclase

scientific article published on 28 October 2004

NO signalling in mice lacking the NO receptor guanylyl cyclase

scientific article published on 11 August 2009

NO signalling in synaptic transmission.

scientific article published in August 2011

NO-Sensitive Guanylate Cyclase Isoforms NO-GC1 and NO-GC2 Contribute to Noise-Induced Inner Hair Cell Synaptopathy.

scientific article published in October 2017

NO-dependent cGMP signalling in neurons and astrocytes

scientific article published on 2 September 2015

NO-sensitive guanylyl cyclase and NO-induced feedback inhibition in cGMP signaling

scientific article

NO/cGMP: the past, the present, and the future

scientific article published on January 2013

Negative feedback regulation within NO/cGMP pathway attenuates vasodilatory response in renovascular hypertension

Nitric oxide dependent signaling via cyclic GMP in dendritic cells regulates migration and T-cell polarization

scientific article published on 20 July 2018

Nitric oxide-sensitive guanylyl cyclase is dispensable for nitrergic signaling and gut motility in mouse intestinal smooth muscle

scientific article published on 25 January 2011

Nitric oxide-sensitive guanylyl cyclase: structure and regulation

scientific article published in November 2004

Nitric oxide/cGMP signaling via guanylyl cyclase isoform 1 modulates glutamate and GABA release in somatosensory cortex of mice

scientific article

PDE2, a component of the NO/cGMP signalling in the hippocampus.

scientific article published in August 2011

Phosphodiesterase 10A Is Tethered to a Synaptic Signaling Complex in Striatum

scientific article

Phosphodiesterase 5 attenuates the vasodilatory response in renovascular hypertension

scientific article

Physiological Functions of NO-Sensitive Guanylyl Cyclase Isoforms

scientific article published in January 2016

Postsynaptic NO/cGMP increases NMDA receptor currents via hyperpolarization-activated cyclic nucleotide-gated channels in the hippocampus.

scientific article published on 28 February 2013

Potent inhibition of aldehyde dehydrogenase-2 by diphenyleneiodonium: focus on nitroglycerin bioactivation.

scientific article published on 21 June 2013

Potent inhibition of nitroglycerin bioactivation by diphenyleneiodonium (DIP).

scientific article

Presynaptic nitric oxide/cGMP facilitates glutamate release via hyperpolarization-activated cyclic nucleotide-gated channels in the hippocampus ⬇️

scientific article published on March 17, 2011

Proatherosclerotic Effect of the α1-Subunit of Soluble Guanylyl Cyclase by Promoting Smooth Muscle Phenotypic Switching

scientific article published on 14 June 2016

Purification and characterization of NO-sensitive guanylyl cyclase

scientific article

Regulation of nitric oxide-sensitive guanylyl cyclase

scientific article

Role of the general base Glu-268 in nitroglycerin bioactivation and superoxide formation by aldehyde dehydrogenase-2.

scientific article published on 8 June 2009

Role of the general base Glu268 in nitroglycerin bioactivation and mechanism-based superoxide formation by aldehyde dehydrogenase-2.

scientific article published on 11 August 2009

Scavenging of nitric oxide by hemoglobin in the tunica media of porcine coronary arteries.

scientific article published on 22 January 2016

Site-directed mutagenesis of aldehyde dehydrogenase-2 suggests three distinct pathways of nitroglycerin biotransformation

scientific article published on 2 May 2011

Smooth muscle-specific deletion of nitric oxide-sensitive guanylyl cyclase is sufficient to induce hypertension in mice

scientific article published on 11 January 2010

Spare guanylyl cyclase NO receptors ensure high NO sensitivity in the vascular system

scientific article

Stimulators of the soluble guanylyl cyclase: promising functional insights from rare coding atherosclerosis-related GUCY1A3 variants

scientific article published on 24 June 2016

The enhanced NO-induced cGMP response induced by long-term L-NAME treatment is not due to enhanced expression of NO-sensitive guanylyl cyclase

scientific article published in October 2003

The function of NO-sensitive guanylyl cyclase: what we can learn from genetic mouse models

scientific article published on 25 July 2009

The neuronal PDE2A3 splice variant is targeted to membranes via dual acylation

cGMP Imaging in Brain Slices Reveals Brain Region-Specific Activity of NO-Sensitive Guanylyl Cyclases (NO-GCs) and NO-GC Stimulators

scholarly article by Stefanie Peters published in August 2018

cGMP produced by NO-sensitive guanylyl cyclase essentially contributes to inflammatory and neuropathic pain by using targets different from cGMP-dependent protein kinase I.

scientific article

cGMP signals in smooth muscle cells and cardiac myocytes.

scientific article published in August 2011

cGMP-dependent signaling pathways in spinal pain processing

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