List of works - Claude-Agnès Reynaud

1(st) French-Israeli International Conference on B Cells and therapeutic antibodies: October 23-25, 2011 Jerusalem, Israel

scientific article published on July 2012

129-Derived Mouse Strains Express an Unstable but Catalytically Active DNA Polymerase Iota Variant

scientific article published on 29 June 2015

A Reassessment of IgM Memory Subsets in Humans

scientific article

A backup role of DNA polymerase kappa in Ig gene hypermutation only takes place in the complete absence of DNA polymerase eta.

scientific article published in May 2009

A bird's eye view on human B cells.

scientific article

A human equivalent of mouse B-1 cells?

scientific article published in December 2011

A single aspartate mutation in the conserved catalytic site of Rev3L generates a hypomorphic phenotype in vivo and in vitro

scientific article published on 25 July 2016

A splenic IgM memory subset with antibacterial specificities is sustained from persistent mucosal responses

article

AID and partners: for better and (not) for worse

scientific article published on 24 March 2011

AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line

scientific article published on 29 July 2002

Allelic exclusion: lesson from GALT species

scientific article

Anti-CD20-mediated B-cell depletion in autoimmune diseases: successes, failures and future perspectives

scientific article published on 30 January 2020

B cell depletion in immune thrombocytopenia reveals splenic long-lived plasma cells

scientific article

BAFF and CD4+ T cells are major survival factors for long-lived splenic plasma cells in a B-cell-depletion context.

scientific article published on 29 January 2018

Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses

scientific article published on 01 January 2020

Clonal Evolution of Autoreactive Germinal Centers

scientific article published on August 2017

Competitive repair pathways in immunoglobulin gene hypermutation.

scientific article published on March 2009

Contribution of DNA polymerase eta to immunoglobulin gene hypermutation in the mouse

scientific article

Cutting edge: DNA polymerases mu and lambda are dispensable for Ig gene hypermutation

scientific article published on 01 April 2002

DNA polymerase eta is involved in hypermutation occurring during immunoglobulin class switch recombination.

scientific article

DNA polymerase eta is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse

scientific article

DNA polymerases in adaptive immunity

scientific article published on 14 March 2008

Editorial overview: Lymphocyte activation and effector functions

scientific article published on 18 April 2014

Editorial overview: Lymphocyte effector subsets: blurring the frontiers

scientific article published on 01 April 2020

Efficacy, safety and immunological profile of combining rituximab with belimumab for adults with persistent or chronic immune thrombocytopenia: results from a prospective phase 2b trial

scientific article published on 13 August 2020

Emergence of long-lived autoreactive plasma cells in the spleen of primary warm auto-immune hemolytic anemia patients treated with rituximab

scientific article

Gene profiling of CD11b⁺ and CD11b⁻ B1 cell subsets reveals potential cell sorting artifacts

scientific article published on March 2012

Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire

scientific article published on 10 June 2004

Human marginal zone B cells.

scientific article published on January 2009

Hypermutation in human B cells in vivo and in vitro.

scientific article

Identification of a human splenic marginal zone B cell precursor with NOTCH2-dependent differentiation properties

scientific article

Identification of a human splenic marginal zone B cell precursor with NOTCH2-dependent differentiation properties

Ig gene hypermutation: a mechanism is due.

scientific article

IgM memory B cells: a mouse/human paradox.

scientific article published on 06 April 2012

IgM memory B cells: specific effectors of innate-like and adaptive responses

scientific article published on 19 October 2019

IgM+IgD+CD27+ B cells are markedly reduced in IRAK-4-, MyD88-, and TIRAP- but not UNC-93B-deficient patients

scientific article (publication date: 13 December 2012)

Immunoglobulin kappa light chain gene rearrangement is impaired in mice deficient for DNA polymerase mu

scientific article (publication date: August 2003)

Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota.

scientific article

Klhl6 Deficiency Impairs Transitional B Cell Survival and Differentiation.

scientific article

LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells

scholarly article by Andreia C Lino et al published 17 July 2018 in Immunity

Long-lived plasma cells in autoimmunity: lessons from B-cell depleting therapy

scientific article

Multiple layers of B cell memory with different effector functions

scientific article published on 25 October 2009

Multiple players in mouse B cell memory

scientific article

Nonoverlapping functions of DNA polymerases mu, lambda, and terminal deoxynucleotidyltransferase during immunoglobulin V(D)J recombination in vivo

scientific article

Normal immune system development in mice lacking the Deltex-1 RING finger domain

scientific article published on February 2005

PCNA ubiquitination-independent activation of polymerase η during somatic hypermutation and DNA damage tolerance.

scientific article published in September 2011

Pms2 and uracil-DNA glycosylases act jointly in the mismatch repair pathway to generate Ig gene mutations at A-T base pairs.

scientific article published on 10 March 2017

Predicting AID off-targets: A step forward.

scientific article published on 15 February 2018

Proteasomal degradation restricts the nuclear lifespan of AID

scientific article published on 12 May 2008

RPA tightens AID to DNA...editing

scientific article

Redundancy of mammalian Y family DNA polymerases in cellular responses to genomic DNA lesions induced by ultraviolet light

scientific article

Role of DNA polymerases eta, iota and zeta in UV resistance and UV-induced mutagenesis in a human cell line.

scientific article

Segmented filamentous bacterium uses secondary and tertiary lymphoid tissues to induce gut IgA and specific T helper 17 cell responses.

scientific article

Somatic diversification in the absence of antigen-driven responses is the hallmark of the IgM+ IgD+ CD27+ B cell repertoire in infants

scientific article published on 2 June 2008

Somatic hypermutation at A/T-rich oligonucleotide substrates shows different strand polarities in Ung-deficient or -proficient backgrounds.

scientific article

Specific over-expression of deltex and a new Kelch-like protein in human germinal center B cells

scientific article

Splenic marginal zone B cells in humans: where do they mutate their Ig receptor?

scientific article

The AID-Cre-ERT2 Model: A Tool for Monitoring B Cell Immune Responses and Generating Selective Hybridomas

scientific article published in January 2017

The human spleen is a major reservoir for long-lived vaccinia virus-specific memory B cells

scientific article published on 3 March 2008

The ups and downs of negative (and positive) selection of B cells

scientific article published on 14 September 2015

Vaccination against encapsulated bacteria in humans: paradoxes.

scientific article published in February 2005

Visualizing antibody affinity maturation in germinal centers

scientific article

What role for AID: mutator, or assembler of the immunoglobulin mutasome?

scientific article

[Ever more humanized mice for new therapeutic applications]

scientific article published on 10 November 2014

[Immunoglobulin gene hypermutation: when error becomes a quality]

scientific article published on 01 May 2007

List of works by Claude-Agnès Reynaud

1(st) French-Israeli International Conference on B Cells and therapeutic antibodies: October 23-25, 2011 Jerusalem, Israel

129-Derived Mouse Strains Express an Unstable but Catalytically Active DNA Polymerase Iota Variant

A Reassessment of IgM Memory Subsets in Humans

A backup role of DNA polymerase kappa in Ig gene hypermutation only takes place in the complete absence of DNA polymerase eta.

A bird's eye view on human B cells.

A human equivalent of mouse B-1 cells?

A single aspartate mutation in the conserved catalytic site of Rev3L generates a hypomorphic phenotype in vivo and in vitro

A splenic IgM memory subset with antibacterial specificities is sustained from persistent mucosal responses

AID and partners: for better and (not) for worse

AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line

Allelic exclusion: lesson from GALT species

Anti-CD20-mediated B-cell depletion in autoimmune diseases: successes, failures and future perspectives

B cell depletion in immune thrombocytopenia reveals splenic long-lived plasma cells

BAFF and CD4+ T cells are major survival factors for long-lived splenic plasma cells in a B-cell-depletion context.

Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses

Clonal Evolution of Autoreactive Germinal Centers

Competitive repair pathways in immunoglobulin gene hypermutation.

Contribution of DNA polymerase eta to immunoglobulin gene hypermutation in the mouse

Cutting edge: DNA polymerases mu and lambda are dispensable for Ig gene hypermutation

DNA polymerase eta is involved in hypermutation occurring during immunoglobulin class switch recombination.

DNA polymerase eta is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse

DNA polymerases in adaptive immunity

Editorial overview: Lymphocyte activation and effector functions

Editorial overview: Lymphocyte effector subsets: blurring the frontiers

Efficacy, safety and immunological profile of combining rituximab with belimumab for adults with persistent or chronic immune thrombocytopenia: results from a prospective phase 2b trial

Emergence of long-lived autoreactive plasma cells in the spleen of primary warm auto-immune hemolytic anemia patients treated with rituximab

Gene profiling of CD11b⁺ and CD11b⁻ B1 cell subsets reveals potential cell sorting artifacts

Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire

Human marginal zone B cells.

Hypermutation in human B cells in vivo and in vitro.

Identification of a human splenic marginal zone B cell precursor with NOTCH2-dependent differentiation properties

Identification of a human splenic marginal zone B cell precursor with NOTCH2-dependent differentiation properties

Ig gene hypermutation: a mechanism is due.

IgM memory B cells: a mouse/human paradox.

IgM memory B cells: specific effectors of innate-like and adaptive responses

IgM+IgD+CD27+ B cells are markedly reduced in IRAK-4-, MyD88-, and TIRAP- but not UNC-93B-deficient patients

Immunoglobulin kappa light chain gene rearrangement is impaired in mice deficient for DNA polymerase mu

Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota.

Klhl6 Deficiency Impairs Transitional B Cell Survival and Differentiation.

LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells

Long-lived plasma cells in autoimmunity: lessons from B-cell depleting therapy

Multiple layers of B cell memory with different effector functions

Multiple players in mouse B cell memory

Nonoverlapping functions of DNA polymerases mu, lambda, and terminal deoxynucleotidyltransferase during immunoglobulin V(D)J recombination in vivo

Normal immune system development in mice lacking the Deltex-1 RING finger domain

PCNA ubiquitination-independent activation of polymerase η during somatic hypermutation and DNA damage tolerance.

Pms2 and uracil-DNA glycosylases act jointly in the mismatch repair pathway to generate Ig gene mutations at A-T base pairs.

Predicting AID off-targets: A step forward.

Proteasomal degradation restricts the nuclear lifespan of AID

RPA tightens AID to DNA...editing

Redundancy of mammalian Y family DNA polymerases in cellular responses to genomic DNA lesions induced by ultraviolet light

Role of DNA polymerases eta, iota and zeta in UV resistance and UV-induced mutagenesis in a human cell line.

Segmented filamentous bacterium uses secondary and tertiary lymphoid tissues to induce gut IgA and specific T helper 17 cell responses.

Somatic diversification in the absence of antigen-driven responses is the hallmark of the IgM+ IgD+ CD27+ B cell repertoire in infants

Somatic hypermutation at A/T-rich oligonucleotide substrates shows different strand polarities in Ung-deficient or -proficient backgrounds.

Specific over-expression of deltex and a new Kelch-like protein in human germinal center B cells

Splenic marginal zone B cells in humans: where do they mutate their Ig receptor?

The AID-Cre-ERT2 Model: A Tool for Monitoring B Cell Immune Responses and Generating Selective Hybridomas

The human spleen is a major reservoir for long-lived vaccinia virus-specific memory B cells

The ups and downs of negative (and positive) selection of B cells

Vaccination against encapsulated bacteria in humans: paradoxes.

Visualizing antibody affinity maturation in germinal centers

What role for AID: mutator, or assembler of the immunoglobulin mutasome?

[Ever more humanized mice for new therapeutic applications]

[Immunoglobulin gene hypermutation: when error becomes a quality]