List of works - Christiane Richter-Landsberg

17-AAG induces cytoplasmic alpha-synuclein aggregate clearance by induction of autophagy

scientific article

ADNP/ADNP2 expression in oligodendrocytes: implication for myelin-related neurodevelopment

scientific article published on 28 August 2015

Activation of PP2A-like phosphatase and modulation of tau phosphorylation accompany stress-induced apoptosis in cultured oligodendrocytes

scientific journal article

Activation of autophagy by rapamycin does not protect oligodendrocytes against protein aggregate formation and cell death induced by proteasomal inhibition

scientific article published on 29 July 2014

Autophagy is activated by proteasomal inhibition and involved in aggresome clearance in cultured astrocytes

scientific article published on November 2010

Collapsin response mediator protein‐2 phosphorylation promotes the reversible retraction of oligodendrocyte processes in response to non‐lethal oxidative stress ⬇️

scientific article published on April 27, 2012

Convergence of heat shock protein 90 with ubiquitin in filamentous alpha-synuclein inclusions of alpha-synucleinopathies

scientific article

Cytotoxic Effects of Tropodithietic Acid on Mammalian Clonal Cell Lines of Neuronal and Glial Origin

scientific article

Differential upregulation of heme oxygenase-1 (HSP32) in glial cells after oxidative stress and in demyelinating disorders

scientific article

Dimethylsulfoniopropionate Promotes Process Outgrowth in Neural Cells and Exerts Protective Effects against Tropodithietic Acid

scientific article published on 6 May 2016

Downregulation of the microtubule associated protein tau impairs process outgrowth and myelin basic protein mRNA transport in oligodendrocytes

scientific article

Effect of proteasome inhibition by MG-132 on HSP27 oligomerization, phosphorylation, and aggresome formation in the OLN-93 oligodendroglia cell line

scientific article

Electrogeneration of O2 .− and H2 O2 Using Polymer-modified Microelectrodes in the Environment of Living Cells

Expression of the small heat-shock protein alphaB-crystallin in tauopathies with glial pathology

scientific article

FAS-dependent cell death in α-synuclein transgenic oligodendrocyte models of multiple system atrophy

scientific article

Formaldehyde induces rapid glutathione export from viable oligodendroglial OLN-93 cells ⬇️

scientific article published on September 24, 2012

HDAC6 inhibition by tubastatin A is protective against oxidative stress in a photoreceptor cell line and restores visual function in a zebrafish model of inherited blindness

scientific article published on 31 August 2017

HDAC6 inhibition results in tau acetylation and modulates tau phosphorylation and degradation in oligodendrocytes

scientific journal article

Higher levels of myelin phospholipids in brains of neuronal α-Synuclein transgenic mice precede myelin loss

scientific article

Inclusion body formation, macroautophagy, and the role of HDAC6 in neurodegeneration

scientific article published on 03 August 2013

Increased Neuronal α-Synuclein Pathology Associates with Its Accumulation in Oligodendrocytes in Mice Modeling α-Synucleinopathies ⬇️

scientific article published on October 15, 2012

Infection of human oligodendroglioma cells by a recombinant measles virus expressing enhanced green fluorescent protein

scientific article published on February 2002

Inhibition of HDAC6 modifies tau inclusion body formation and impairs autophagic clearance

scientific article

Inhibition of UCH-L1 in oligodendroglial cells results in microtubule stabilization and prevents α-synuclein aggregate formation by activating the autophagic pathway: implications for multiple system atrophy

scientific article published on 5 May 2015

Inhibition of protein deubiquitination by PR-619 activates the autophagic pathway in OLN-t40 oligodendroglial cells

scientific article published on September 2013

International Meeting Molecular Neurodegeneration: News and Views in Molecular Neuroscience in Health and Disease. Delmenhorst, Germany, July 20-22, 2015.

scientific article published on 29 August 2015

Involvement of Macroautophagy in Multiple System Atrophy and Protein Aggregate Formation in Oligodendrocytes ⬇️

scientific article published on March 13, 2012

Membrane lipid modification by docosahexaenoic acid (DHA) promotes the formation of α-synuclein inclusion bodies immunopositive for SUMO-1 in oligodendroglial cells after oxidative stress

scientific article published on 20 August 2010

Membrane lipid modification by polyunsaturated fatty acids sensitizes oligodendroglial OLN-93 cells against oxidative stress and promotes up-regulation of heme oxygenase-1 (HSP32).

scientific article published on 22 January 2010

Mitochondrial impairment and oxidative stress compromise autophagosomal degradation of α-synuclein in oligodendroglial cells

scientific article published on 24 July 2015

Mitochondrial pathway is involved in hydrogen-peroxide-induced apoptotic cell death of oligodendrocytes

scientific article published in May 2004

Nitration of tau protein is linked to neurodegeneration in tauopathies

scientific article published on September 2003

Oxidative stress promotes uptake, accumulation, and oligomerization of extracellular α-synuclein in oligodendrocytes

scientific article published on 12 November 2013

Proteasome Inhibition Stabilizes Tau Inclusions in Oligodendroglial Cells that Occur after Treatment with Okadaic Acid ⬇️

scientific article published on October 1, 2003

Proteasome inhibition by MG-132 induces apoptotic cell death and mitochondrial dysfunction in cultured rat brain oligodendrocytes but not in astrocytes

scientific article

Protein aggregate formation in oligodendrocytes: tau and the cytoskeleton at the intersection of neuroprotection and neurodegeneration

scientific article published on 17 June 2015

Proteolytic stress causes heat shock protein induction, tau ubiquitination, and the recruitment of ubiquitin to tau-positive aggregates in oligodendrocytes in culture.

scientific article

Role of the oligodendroglial cytoskeleton in differentiation and myelination

scientific article published on December 2009

SUMO-1 is associated with a subset of lysosomes in glial protein aggregate diseases

scientific article published on 15 November 2012

Short-term incubation of gabapentin or pregabalin does not affect chemically induced injury in neuronal cell models in vitro.

scientific article

TRPM3 is expressed in sphingosine-responsive myelinating oligodendrocytes

scientific article published on 15 February 2010

Tau-inclusion body formation in oligodendroglia: the role of stress proteins and proteasome inhibition

scientific article published in November 2004

The Small Heat Shock Protein HSP25/27 (HspB1) Is Abundant in Cultured Astrocytes and Associated with Astrocytic Pathology in Progressive Supranuclear Palsy and Corticobasal Degeneration

scientific article

The cytoskeleton in oligodendrocytes. Microtubule dynamics in health and disease

scientific article published on 04 December 2007

The dynamic instability of microtubules is required for aggresome formation in oligodendroglial cells after proteolytic stress

scientific article published on January 2006

The expression of tubulin polymerization promoting protein TPPP/p25alpha is developmentally regulated in cultured rat brain oligodendrocytes and affected by proteolytic stress

scientific article published in December 2008

The oligodendroglia cytoskeleton in health and disease

article

The small heat shock protein HSP25 protects astrocytes against stress induced by proteasomal inhibition

scientific article

The small molecule inhibitor PR-619 of deubiquitinating enzymes affects the microtubule network and causes protein aggregate formation in neural cells: Implications for neurodegenerative diseases ⬇️

scientific article published on April 28, 2012

Triethyltin-induced stress responses and apoptotic cell death in cultured oligodendrocytes

scientific article published in May 2004

alpha-Synuclein promotes the recruitment of tau to protein inclusions in oligodendroglial cells: effects of oxidative and proteolytic stress

scientific article published on 6 March 2009

List of works by Christiane Richter-Landsberg

17-AAG induces cytoplasmic alpha-synuclein aggregate clearance by induction of autophagy

ADNP/ADNP2 expression in oligodendrocytes: implication for myelin-related neurodevelopment

Activation of PP2A-like phosphatase and modulation of tau phosphorylation accompany stress-induced apoptosis in cultured oligodendrocytes

Activation of autophagy by rapamycin does not protect oligodendrocytes against protein aggregate formation and cell death induced by proteasomal inhibition

Autophagy is activated by proteasomal inhibition and involved in aggresome clearance in cultured astrocytes

Collapsin response mediator protein‐2 phosphorylation promotes the reversible retraction of oligodendrocyte processes in response to non‐lethal oxidative stress ⬇️

Convergence of heat shock protein 90 with ubiquitin in filamentous alpha-synuclein inclusions of alpha-synucleinopathies

Cytotoxic Effects of Tropodithietic Acid on Mammalian Clonal Cell Lines of Neuronal and Glial Origin

Differential upregulation of heme oxygenase-1 (HSP32) in glial cells after oxidative stress and in demyelinating disorders

Dimethylsulfoniopropionate Promotes Process Outgrowth in Neural Cells and Exerts Protective Effects against Tropodithietic Acid

Downregulation of the microtubule associated protein tau impairs process outgrowth and myelin basic protein mRNA transport in oligodendrocytes

Effect of proteasome inhibition by MG-132 on HSP27 oligomerization, phosphorylation, and aggresome formation in the OLN-93 oligodendroglia cell line

Electrogeneration of O2 .− and H2 O2 Using Polymer-modified Microelectrodes in the Environment of Living Cells

Expression of the small heat-shock protein alphaB-crystallin in tauopathies with glial pathology

FAS-dependent cell death in α-synuclein transgenic oligodendrocyte models of multiple system atrophy

Formaldehyde induces rapid glutathione export from viable oligodendroglial OLN-93 cells ⬇️

HDAC6 inhibition by tubastatin A is protective against oxidative stress in a photoreceptor cell line and restores visual function in a zebrafish model of inherited blindness

HDAC6 inhibition results in tau acetylation and modulates tau phosphorylation and degradation in oligodendrocytes

Higher levels of myelin phospholipids in brains of neuronal α-Synuclein transgenic mice precede myelin loss

Inclusion body formation, macroautophagy, and the role of HDAC6 in neurodegeneration

Increased Neuronal α-Synuclein Pathology Associates with Its Accumulation in Oligodendrocytes in Mice Modeling α-Synucleinopathies ⬇️

Infection of human oligodendroglioma cells by a recombinant measles virus expressing enhanced green fluorescent protein

Inhibition of HDAC6 modifies tau inclusion body formation and impairs autophagic clearance

Inhibition of UCH-L1 in oligodendroglial cells results in microtubule stabilization and prevents α-synuclein aggregate formation by activating the autophagic pathway: implications for multiple system atrophy

Inhibition of protein deubiquitination by PR-619 activates the autophagic pathway in OLN-t40 oligodendroglial cells

International Meeting Molecular Neurodegeneration: News and Views in Molecular Neuroscience in Health and Disease. Delmenhorst, Germany, July 20-22, 2015.

Involvement of Macroautophagy in Multiple System Atrophy and Protein Aggregate Formation in Oligodendrocytes ⬇️

Membrane lipid modification by docosahexaenoic acid (DHA) promotes the formation of α-synuclein inclusion bodies immunopositive for SUMO-1 in oligodendroglial cells after oxidative stress

Membrane lipid modification by polyunsaturated fatty acids sensitizes oligodendroglial OLN-93 cells against oxidative stress and promotes up-regulation of heme oxygenase-1 (HSP32).

Mitochondrial impairment and oxidative stress compromise autophagosomal degradation of α-synuclein in oligodendroglial cells

Mitochondrial pathway is involved in hydrogen-peroxide-induced apoptotic cell death of oligodendrocytes

Nitration of tau protein is linked to neurodegeneration in tauopathies

Oxidative stress promotes uptake, accumulation, and oligomerization of extracellular α-synuclein in oligodendrocytes

Proteasome Inhibition Stabilizes Tau Inclusions in Oligodendroglial Cells that Occur after Treatment with Okadaic Acid ⬇️

Proteasome inhibition by MG-132 induces apoptotic cell death and mitochondrial dysfunction in cultured rat brain oligodendrocytes but not in astrocytes

Protein aggregate formation in oligodendrocytes: tau and the cytoskeleton at the intersection of neuroprotection and neurodegeneration

Proteolytic stress causes heat shock protein induction, tau ubiquitination, and the recruitment of ubiquitin to tau-positive aggregates in oligodendrocytes in culture.

Role of the oligodendroglial cytoskeleton in differentiation and myelination

SUMO-1 is associated with a subset of lysosomes in glial protein aggregate diseases

Short-term incubation of gabapentin or pregabalin does not affect chemically induced injury in neuronal cell models in vitro.

TRPM3 is expressed in sphingosine-responsive myelinating oligodendrocytes

Tau-inclusion body formation in oligodendroglia: the role of stress proteins and proteasome inhibition

The Small Heat Shock Protein HSP25/27 (HspB1) Is Abundant in Cultured Astrocytes and Associated with Astrocytic Pathology in Progressive Supranuclear Palsy and Corticobasal Degeneration

The cytoskeleton in oligodendrocytes. Microtubule dynamics in health and disease

The dynamic instability of microtubules is required for aggresome formation in oligodendroglial cells after proteolytic stress

The expression of tubulin polymerization promoting protein TPPP/p25alpha is developmentally regulated in cultured rat brain oligodendrocytes and affected by proteolytic stress

The oligodendroglia cytoskeleton in health and disease

The small heat shock protein HSP25 protects astrocytes against stress induced by proteasomal inhibition

The small molecule inhibitor PR-619 of deubiquitinating enzymes affects the microtubule network and causes protein aggregate formation in neural cells: Implications for neurodegenerative diseases ⬇️

Triethyltin-induced stress responses and apoptotic cell death in cultured oligodendrocytes

alpha-Synuclein promotes the recruitment of tau to protein inclusions in oligodendroglial cells: effects of oxidative and proteolytic stress