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List of works by Beate Koksch

A New Approach to Glycopeptides

scientific article published on 01 May 1999

A Self-Assembling Peptide Scaffold for the Multivalent Presentation of Antigens

scientific article published on 4 June 2015

A Sustainable, Semi-Continuous Flow Synthesis of Hydantoins

scientific article

A beta/gamma motif to mimic alpha-helical turns in proteins

scientific article published in February 2010

A helix-forming αβγ-chimeric peptide with catalytic activity: a hybrid peptide ligase ⬇️

scientific article published on February 15, 2011

A molecular dynamics study of the formation, stability, and oligomerization state of two designed coiled coils: possibilities and limitations

scientific article published on 8 September 2005

A systematic study of fundamentals in α-helical coiled coil mimicry by alternating sequences of β- and γ-amino acids.

scientific article published on 3 June 2011

Advanced approaches for the characterization of a de novo designed antiparallel coiled coil peptide

scientific article published on 24 February 2005

Amide-I and -II vibrations of the cyclic beta-sheet model peptide gramicidin S in the gas phase

scientific article published in February 2010

Amide-to-ester substitution in coiled coils: the effect of removing hydrogen bonds on protein structure.

scientific article

Amyloidogenic peptides at hydrophobic-hydrophilic interfaces: coordination affinities and the chelate effect dictate the competitive binding of Cu2+ and Zn2+.

scientific article published on 12 July 2011

An Intrinsic Hydrophobicity Scale for Amino Acids and Its Application to Fluorinated Compounds

scientific article published on 10 May 2019

An unusual interstrand H-bond stabilizes the heteroassembly of helical αβγ-chimeras with natural peptides

scientific article

Approaches to Obtaining Fluorinated α-Amino Acids

scientific article published on 22 August 2019

Balancing selectivity vs stability using molecular dynamics and umbrella sampling

scientific article published on 11 March 2014

Biocatalysis with Unnatural Amino Acids: Enzymology Meets Xenobiology

scientific article published on 13 January 2017

Catalytic Activity of Peptide-Nanoparticle Conjugates Regulated by a Conformational Change

scientific article published on 19 September 2017

Catalytically Active Peptide-Gold Nanoparticle Conjugates: Prospecting for Artificial Enzymes

scientific article published on 06 January 2020

Cationic membrane-active peptides - anticancer and antifungal activity as well as penetration into human skin

scientific article published on May 2014

Chemical aminoacylation of tRNAs with fluorinated amino acids for in vitro protein mutagenesis

scientific article published on 20 April 2010

Chemical labeling strategy with (R)- and (S)-trifluoromethylalanine for solid state 19F NMR analysis of peptaibols in membranes

scientific article published in November 2009

Coassembly Generates Peptide Hydrogel with Wound Dressing Material Properties

scientific article published on 07 April 2020

Coiled-coils in phage display screening: insight into exceptional selectivity provided by molecular dynamics.

scientific article published on 12 February 2015

Compatibility of the conformationally rigid CF3-Bpg side chain with the hydrophobic coiled-coil interface

scientific article published on 13 April 2010

Concluding the amyloid formation pathway of a coiled-coil-based peptide from the size of the critical nucleus

scientific article published on 26 September 2014

Conjugate hydrotrifluoromethylation of α,β-unsaturated acyl-oxazolidinones: synthesis of chiral fluorinated amino acids ⬇️

scientific article published on November 21, 2012

Deciphering the Fluorine Code-The Many Hats Fluorine Wears in a Protein Environment.

scientific article published on 12 August 2017

Design and characterization of endosomal-pH-responsive coiled coils for constructing an artificial membrane fusion system

scientific article published on 18 April 2011

Design, synthesis, inhibition studies, and molecular modeling of pepstatin analogues addressing different secreted aspartic proteinases of Candida albicans

scientific article

Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors

scientific article

Direct one-step 18F-labeling of peptides via nucleophilic aromatic substitution

scientific article published in December 2009

Directing the secondary structure of polypeptides at will: from helices to amyloids and back again?

scientific article

Discovery and Investigation of Natural Editing Function against Artificial Amino Acids in Protein Translation

scientific article (publication date: 25 January 2017)

Editorial overview: Synthetic biomolecules: Biopolymers

scientific article published in October 2017

Effects of fluorination on the folding kinetics of a heterodimeric coiled coil

scientific article published in December 2009

Enzymatically triggered amyloid formation: an approach for studying peptide aggregation

scientific article published on 30 March 2010

Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins

scientific article

Evaluation of the molecular interactions of fluorinated amino acids with native polypeptides

scientific article

Exploiting Oligo(amido amine) Backbones for the Multivalent Presentation of Coiled-Coil Peptides

scientific article published on 16 July 2015

Exploring the conformational preferences of 20-residue peptides in isolation: Ac-Ala19-Lys + H(+)vs. Ac-Lys-Ala19 + H(+) and the current reach of DFT.

scientific article published in March 2015

Fluorinated amino acids in amyloid formation: a symphony of size, hydrophobicity and α-helix propensity

article published in 2014

Fluorinated amino acids: compatibility with native protein structures and effects on protein-protein interactions.

scientific article

Fluorine in Peptide Design and Protein Engineering

article by Christian Jäckel & Beate Koksch published November 2005 in European Journal of Organic Chemistry

Fluorine in a native protein environment--How the spatial demand and polarity of fluoroalkyl groups affect protein folding

scientific article published in June 2006

Fluorine in protein environments: a QM and MD study

scientific article published in December 2009

Fluorine teams up with water to restore inhibitor activity to mutant BPTI.

scientific article published on 12 June 2015

Fluoro-modified chemotactic peptides: fMLF analogues

scientific article

Following polypeptide folding and assembly with conformational switches

scientific article published on 07 October 2008

Formation of α-helical nanofibers by mixing β-structured and α-helical coiled coil peptides

scientific article published in November 2012

From alpha-helix to beta-sheet--a reversible metal ion induced peptide secondary structure switch

scientific article published on 16 June 2005

Global substitution of hemeproteins with noncanonical amino acids in Escherichia coli with intact cofactor maturation machinery

scientific article published on 29 June 2017

Hexafluoroacetone as a Protecting and Activating Reagent: Synthesis of New Types of Fluoro-Substituted α-Amino, α-Hydroxy and α-Mercapto Acids

Highly dynamic motion of crown ethers along oligolysine peptide chains ⬇️

scientific article published on August 30, 2009

How C(alpha)-Fluoroalkyl amino acids and peptides interact with enzymes: studies concerning the influence on proteolytic stability, enzymatic resolution and peptide coupling

scientific article published on January 2006

How cations change peptide structure.

scientific article

How metal ions affect amyloid formation: Cu2+- and Zn2+-sensitive peptides

scientific article published in March 2008

How post-translational modifications influence amyloid formation: a systematic study of phosphorylation and glycosylation in model peptides

scientific article published in July 2010

Impact of fluorination on proteolytic stability of peptides in human blood plasma

scientific article published on 2 April 2013

Impact of fluorination on proteolytic stability of peptides: a case study with α-chymotrypsin and pepsin

scientific article published on 6 September 2014

Impact of multivalent charge presentation on peptide-nanoparticle aggregation

scientific article published on 15 May 2015

Inhibition of Amyloid Aggregation by Formation of Helical Assemblies ⬇️

scientific article published on September 12, 2011

Inhibition of peptide aggregation by means of enzymatic phosphorylation

scientific article published on 18 November 2016

Intramolecular charge interactions as a tool to control the coiled-coil-to-amyloid transformation

scientific article published in January 2008

Investigation of the network of preferred interactions in an artificial coiled-coil association using the peptide array technique ⬇️

scientific article published on April 25, 2012

Investigation of the synthetic route to pepstatin analogues by SPPS using O-protected and O-unprotected statine as building blocks

scientific article published in April 2009

Laboratory evolution of Escherichia coli enables life based on fluorinated amino acids

scholarly article published 10 June 2019

Mechanism of discrimination of isoleucyl-tRNA synthetase against nonproteinogenic α-aminobutyrate and its fluorinated analogues

scientific article published on 18 September 2019

Membrane binding and structure of de novo designed alpha-helical cationic coiled-coil-forming peptides

scientific article published in June 2006

Membrane binding of peptide models for early stages of amyloid formation: Lipid packing counts more than charge

scientific article published on 28 April 2016

Modifizierung von Peptiden

scientific article published in January 1998

Molecular Interactions of Fluorinated Amino Acids in a Native Polypeptide Environment

Multiomics Analysis Provides Insight into the Laboratory Evolution of Escherichia coli toward the Metabolic Usage of Fluorinated Indoles

scientific article published in 2020

Multiple glycosylation of de novo designed alpha-helical coiled coil peptides

scientific article published on 27 March 2010

Multivalency as a chemical organization and action principle

scientific article published on 05 September 2012

NFGAIL Amyloid Oligomers: The Onset of Beta-Sheet Formation and the Mechanism for Fibril Formation

scientific article published on 13 December 2017

Nanoparticle-induced folding and fibril formation of coiled-coil-based model peptides

scientific article published on 01 June 2010

Nanoscale imaging reveals laterally expanding antimicrobial pores in lipid bilayers ⬇️

scientific article published on May 13, 2013

Native like helices in a specially designed β peptide in the gas phase

scientific article published on February 2015

Orthogonal translation meets electron transfer: in vivo labeling of cytochrome c for probing local electric fields

scientific article published on 23 February 2015

Peptide adsorption to cyanine dye aggregates revealed by cryo-transmission electron microscopy

scientific article

Position-dependent effects of fluorinated amino acids on the hydrophobic core formation of a heterodimeric coiled coil

scientific article published in August 2009

Position-dependent impact of hexafluoroleucine and trifluoroisoleucine on protease digestion

scientific article published on 22 December 2017

Proline-glutamate chimera's side chain conformation directs the type of β-hairpin structure

scientific article

Protease-catalyzed peptide synthesis for the site-specific incorporation of alpha-fluoroalkyl amino acids into peptides

scientific article

Random coils, beta-sheet ribbons, and alpha-helical fibers: one peptide adopting three different secondary structures at will

scientific article published in February 2006

Selection of a buried salt bridge by phage display

scientific article

Self-Assembling Peptides as Extracellular Matrix Mimics to Influence Stem Cell's Fate

Simple machine-assisted protocol for solid-phase synthesis of depsipeptides

scientific article published in January 2007

Specific in situ discrimination of amyloid fibrilsversus α-helical fibres by the fluorophore NIAD-4 ⬇️

scientific article published on November 24, 2011

Structural determinants of coiled coil mechanics

scientific article published on 01 May 2019

Structure analysis of an amyloid-forming model peptide by a systematic glycine and proline scan

scientific article published on 13 July 2011

Substrate specificity of an actively assembling amyloid catalyst

scientific article published on 16 November 2016

Switchable electrostatic interactions between gold nanoparticles and coiled coil peptides direct colloid assembly

scientific article published on 17 November 2008

Synthesis of enantiomerically pure (2S,3S)-5,5,5-trifluoroisoleucine and (2R,3S)-5,5,5-trifluoro-allo-isoleucine

scientific article published on 2 October 2013

Synthetic strategies to alpha-trifluoromethyl and alpha-difluoromethyl substituted alpha-amino acids

scientific article published on 26 June 2008

Tailored Presentation of Carbohydrates on a Coiled Coil-Based Scaffold for Asialoglycoprotein Receptor Targeting

scientific article published on 9 June 2015

The Amyloid Precursor Protein C-Terminal Fragment C100 Occurs in Monomeric and Dimeric Stable Conformations and Binds γ-Secretase Modulators ⬇️

scientific article published on January 11, 2011

The Impact of Halogenated Phenylalanine Derivatives on NFGAIL Amyloid Formation

scientific article published on 23 September 2020

The protofilament architecture of a de novo designed coiled coil-based amyloidogenic peptide

Towards identifying preferred interaction partners of fluorinated amino acids within the hydrophobic environment of a dimeric coiled coil peptide

scientific article

Towards understanding secondary structure transitions: phosphorylation and metal coordination in model peptides

scientific article published on 29 March 2010

Triggers for β-sheet formation at the hydrophobic-hydrophilic interface: high concentration, in-plane orientational order, and metal ion complexation

scientific article published on 07 November 2011

Using the Potential of Fluorine for Peptide and Protein Modification

β- and γ-Amino Acids at α-Helical Interfaces: Toward the Formation of Highly Stable Foldameric Coiled Coils

scientific article published on 28 October 2014

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