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List of works by Andrea Olschewski

A novel channelopathy in pulmonary arterial hypertension

scientific article

A pro-con debate: current controversies in PAH pathogenesis at the American Thoracic Society International Conference in 2017

scientific article published on 07 June 2018

ALK3 undergoes ligand-independent homodimerization and BMP-induced heterodimerization with ALK2

scientific article published on 15 September 2018

Activated prostaglandin D2 receptors on macrophages enhance neutrophil recruitment into the lung

scientific article published on 11 January 2016

Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C

scientific article

Amitriptyline and carbamazepine utilize voltage-gated ion channel suppression to impair excitability of sensory dorsal horn neurons in thin tissue slice: An in vitro study

scientific article published on 2 March 2016

Angiostatic factors in the pulmonary endarterectomy material from chronic thromboembolic pulmonary hypertension patients cause endothelial dysfunction

scientific article

Automated integer programming based separation of arteries and veins from thoracic CT images.

scientific article published on 6 May 2016

BDNF/TrkB signaling augments smooth muscle cell proliferation in pulmonary hypertension

scientific article published on 8 October 2012

Basement Membrane Remodelling Controls Endothelial Function in IPAH

scientific article published on 11 March 2020

Biomarkers in pulmonary hypertension: what do we know?

scientific article published on July 2013

Blocking potassium channels: a new principle for treating restenosis?

scientific article published on 14 December 2010

CD133+ cells in pulmonary arterial hypertension

scientific article

Changes in pulmonary exercise haemodynamics in scleroderma: a 4-year prospective study

scientific article

Characterization of GDF2 Mutations and Levels of BMP9 and BMP10 in Pulmonary Arterial Hypertension

scientific article published on 01 March 2020

Characterization of Patients With Borderline Pulmonary Arterial Pressure

scientific article published on 01 December 2014

Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange

scholarly article

Compartment-specific expression of collagens and their processing enzymes in intrapulmonary arteries of IPAH patients

scientific article published on 3 April 2015

Comprehensive analysis of inflammatory markers in chronic thromboembolic pulmonary hypertension patients

scientific article

Contribution of the K(Ca) channel to membrane potential and O2 sensitivity is decreased in an ovine PPHN model

scientific article published in November 2002

Determination of cardiac output with dynamic contrast-enhanced computed tomography.

scientific article published on 23 August 2013

Disconnect between Fibrotic Response and Right Ventricular Dysfunction

scientific article published on 01 June 2019

Distinct differences in gene expression patterns in pulmonary arteries of patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis with pulmonary hypertension.

scientific article

Docking of Meprin α to Heparan Sulphate Protects the Endothelium from Inflammatory Cell Extravasation

scientific article published on 20 September 2018

Docosahexaenoic acid (DHA)-induced heme oxygenase-1 attenuates cytotoxic effects of DHA in vascular smooth muscle cells

scientific article published on 13 August 2013

Docosahexaenoic acid causes rapid pulmonary arterial relaxation via KCa channel-mediated hyperpolarisation in pulmonary hypertension

scientific article

Docosahexaenoic acid-induced unfolded protein response, cell cycle arrest, and apoptosis in vascular smooth muscle cells are triggered by Ca2+-dependent induction of oxidative stress ⬇️

scientific article published on March 3, 2012

Double-stranded RNA attenuates the barrier function of human pulmonary artery endothelial cells

scientific article

Endothelial Dysfunction Following Enhanced TMEM16A Activity in Human Pulmonary Arteries

scientific article published on 28 August 2020

Endothelin-1 driven proliferation of pulmonary arterial smooth muscle cells is c-fos dependent.

scientific article published on 10 July 2014

Endothelin-1 inhibits background two-pore domain channel TASK-1 in primary human pulmonary artery smooth muscle cells

scientific article published on 2 February 2009

Enhancement of delayed-rectifier potassium conductance by low concentrations of local anaesthetics in spinal sensory neurones.

scientific article published in June 2002

Fra2 Overexpression in Mice Leads to Non-allergic Asthma Development in an IL-13 Dependent Manner

Functional and molecular factors associated with TAPSE in hypoxic pulmonary hypertension

scientific article published on 22 April 2016

Genetic determinants of risk and survival in pulmonary arterial hypertension

article

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis

scientific article published on 05 December 2018

Graded response of K+ current, membrane potential, and [Ca2+]i to hypoxia in pulmonary arterial smooth muscle

scientific article published in November 2002

Healthy Lung Vessel Morphology Derived From Thoracic Computed Tomography.

scientific article

High-mobility group box-1 induces vascular remodelling processes via c-Jun activation

scientific article published on 28 February 2015

Hypoxia increases membrane metallo-endopeptidase expression in a novel lung cancer ex vivo model - role of tumor stroma cells

scientific article published on 25 January 2014

Hypoxia-induced cisplatin resistance is reversible and growth rate independent in lung cancer cells

scientific article published on 12 June 2011

Hypoxic vascular response and ventilation/perfusion matching in end-stage COPD may depend on p22phox.

scientific article published on 20 July 2017

IL-1 receptor blockade skews inflammation towards Th2 in a mouse model of systemic sclerosis

scientific article published on 29 September 2019

Identification of novel rare sequence variation underlying heritable pulmonary arterial hypertension

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

scientific article published on 12 April 2018

Impact of TASK-1 in Human Pulmonary Artery Smooth Muscle Cells

scientific article published on 30 March 2006

Impact of atomization technique on the stability and transport efficiency of nebulized liposomes harboring different surface characteristics

scientific article published on November 2014

Importance of kynurenine in pulmonary hypertension.

scientific article published on 13 July 2017

Increased Expression of p22phox Mediates Airway Hyperresponsiveness in an Experimental Model of Asthma.

scientific article

Interaction of Tissue Engineering Substrates with Serum Proteins and Its Influence on Human Primary Endothelial Cells

scientific article published on 5 January 2017

Interaction of eosinophils with endothelial cells is modulated by prostaglandin EP4 receptors

scientific article

Ion Channels in Pulmonary Hypertension: A Therapeutic Interest?

scientific article published on 14 October 2018

Ion channels and transporters as therapeutic targets in the pulmonary circulation

scientific article

Ketamine impairs excitability in superficial dorsal horn neurones by blocking sodium and voltage-gated potassium currents

scientific article published on November 2005

Lack of ABCG2 Leads to Biventricular Dysfunction and Remodeling in Response to Hypoxia

scientific article published on 21 February 2017

Letter by Olschewski et al Regarding Article, “Upregulation of K 2P 3.1 K + Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation”

scientific article published on 01 March 2016

Liposomal nanoparticles encapsulating iloprost exhibit enhanced vasodilation in pulmonary arteries

scientific article

Local anaesthetics block hyperpolarization-activated inward current in rat small dorsal root ganglion neurones

scientific article

Long non-coding RNAs influence the transcriptome in pulmonary arterial hypertension: the role of PAXIP1-AS1

scientific article published on 16 January 2019

Loss of SMAD3 Promotes Vascular Remodeling in Pulmonary Arterial Hypertension via MRTF Disinhibition

scientific article published on 2 November 2017

Mechanisms of lidocaine's action on subtypes of spinal dorsal horn neurons subject to the diverse roles of Na(+) and K(+) channels in action potential generation

scientific article published in August 2014

Meperidine suppresses the excitability of spinal dorsal horn neurons

scientific article

Meprinβ, a novel mediator of vascular remodelling underlying pulmonary hypertension

scientific article published on 31 January 2014

Mexiletine and lidocaine suppress the excitability of dorsal horn neurons.

scientific article published in July 2009

Microarray analysis in pulmonary hypertension

scientific article

Mild Elevation of Pulmonary Arterial Pressure as a Predictor of Mortality

scientific article

Nano- and Micropatterned Polycaprolactone Cellulose Composite Surfaces with Tunable Protein Adsorption, Fibrin Clot Formation, and Endothelial Cellular Response

scientific article published on 29 May 2019

No erythropoietin-induced growth is observed in non-small cell lung cancer cells

scientific article published on 12 December 2017

No indication of insulin resistance in idiopathic PAH with preserved physical activity

scientific article published on 26 March 2020

Non-invasive determination of pulmonary hypertension with dynamic contrast-enhanced computed tomography: a pilot study

scientific article

Nordexfenfluramine causes more severe pulmonary vasoconstriction than dexfenfluramine ⬇️

scientific article published on November 7, 2003

Nuclear and cytoplasmic death receptor 5 as prognostic factors in patients with non-small cell lung cancer treated with chemotherapy

scientific article

Oleic acid inhibits alveolar fluid reabsorption: a role in acute respiratory distress syndrome?

scientific article

Opposite effects of redox status on membrane potential, cytosolic calcium, and tone in pulmonary arteries and ductus arteriosus

scientific article published on 3 July 2003

Origin of neomuscularized vessels in mice exposed to chronic hypoxia.

scientific article

PAR-2 inhibition reverses experimental pulmonary hypertension

scientific article

PDGFRα and αSMA mark two distinct mesenchymal cell populations involved in parenchymal and vascular remodeling in pulmonary fibrosis

scientific article published on 05 February 2020

Panobinostat reduces hypoxia-induced cisplatin resistance of non-small cell lung carcinoma cells via HIF-1α destabilization

scientific article

Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018

article

Peroxisome proliferator-activated receptor-β/δ, the acute signaling factor in prostacyclin-induced pulmonary vasodilation

scientific article published on 20 October 2011

Pressure Overload Creates Right Ventricular Diastolic Dysfunction in a Mouse Model: Assessment by Echocardiography

scientific article published in April 2015

Prostacyclin and its analogues in the treatment of pulmonary hypertension

scientific article published on May 2004

Quantification of tortuosity and fractal dimension of the lung vessels in pulmonary hypertension patients

scientific article published on 31 January 2014

Redox regulation of ion channels in the pulmonary circulation

scientific article published on 30 June 2014

Resident cell lineages are preserved in pulmonary vascular remodeling

scientific article

Rho-Kinase Inhibition Ameliorates Dasatinib-Induced Endothelial Dysfunction and Pulmonary Hypertension.

scientific article

Role of ion channels in acute and chronic responses of the pulmonary vasculature to hypoxia

scientific article published on 27 April 2006

Role of store-operated calcium channels and calcium sensitization in normoxic contraction of the ductus arteriosus

scientific article published on 18 September 2006

Src tyrosine kinase is crucial for potassium channel function in human pulmonary arteries.

scientific article

Subacute hypoxia decreases voltage-activated potassium channel expression and function in pulmonary artery myocytes

scientific journal article

TASK-1 (KCNK3) channels in the lung: from cell biology to clinical implications.

scientific article published on 9 November 2017

TASK-1 Regulates Apoptosis and Proliferation in a Subset of Non-Small Cell Lung Cancers

scientific article

TGF-β directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury

scientific article published on 09 December 2013

TMEM16A Potentiation: Possible Drawbacks

scientific article published on 28 May 2020

TR3 is involved in hypoxia-induced apoptosis resistance in lung cancer cells downstream of HIF-1α.

scientific article published on 21 June 2017

TRPV4 mutations in children with congenital distal spinal muscular atrophy

scientific article

Targeting TASK-1 channels as a therapeutic approach

scientific article published on January 2010

Targeting TMEM16A to reverse vasoconstriction and remodelling in idiopathic PAH

scientific article published on 25 April 2019

The Role of PGE2 in Alveolar Epithelial and Lung Microvascular Endothelial Crosstalk

scientific article published on 11 August 2017

The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells.

scientific article published on 29 May 2018

The inflammatory cell landscape in the lungs of patients with idiopathic pulmonary arterial hypertension.

scientific article published on 25 January 2018

The role of inflammation in hypoxic pulmonary hypertension: from cellular mechanisms to clinical phenotypes

scientific article

Thrombin impairs alveolar fluid clearance by promoting endocytosis of Na+,K+-ATPase

scientific article published on 13 July 2005

Transcriptome profiling reveals the complexity of pirfenidone effects in idiopathic pulmonary fibrosis

scientific article published on 22 November 2018

Use of ECG and Other Simple Non-Invasive Tools to Assess Pulmonary Hypertension

scientific article

Zero reference level for right heart catheterisation

scientific article published on 21 June 2013

[Hemodynamic Definition of Pulmonary Hypertension: Commentary on the Proposed Change by the 6th World Symposium on Pulmonary Hypertension]

scientific article published on 05 July 2019

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