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List of works by Almut Schulze

3D Growth of Cancer Cells Elicits Sensitivity to Kinase Inhibitors but Not Lipid Metabolism Modifiers

scientific article published on 26 November 2018

6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells.

scientific article published on 16 January 2017

A MYC-GCN2-eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer

scientific article published on 04 November 2019

A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration

scientific article

A fresh look at cancer metabolism in a historical setting ⬇️

scientific article published on March 18, 2011

A new player in the orchestra of cell growth: SREBP activity is regulated by mTORC1 and contributes to the regulation of cell and organ size

scientific article published on February 2009

Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress

scientific article

Activation of cyclin A gene expression by the cyclin encoded by human herpesvirus-8.

scientific article published on March 1999

Analysis of the transcriptional program induced by Raf in epithelial cells

scientific article

Anchorage-dependent transcription of the cyclin A gene

scientific article published on September 1996

Antagonism between FOXO and MYC Regulates Cellular Powerhouse

scientific article published on 25 April 2013

Cathepsin Inhibition Modulates Metabolism and Polarization of Tumor-Associated Macrophages

scientific article published on 10 September 2020

Cell cycle regulation of the cyclin A gene promoter is mediated by a variant E2F site

scientific article

Cellular fatty acid metabolism and cancer

scientific article published on 20 June 2013

Cholesteryl esters: fueling the fury of prostate cancer.

scientific article published in March 2014

Direct control of caveolin-1 expression by FOXO transcription factors

scientific article

Erratum: Corrigendum: How cancer metabolism is tuned for proliferation and vulnerable to disruption

scientific article published in Nature

FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression

scientific article

Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation

scientific article published on 25 September 2014

Flicking the Warburg Switch—Tyrosine Phosphorylation of Pyruvate Dehydrogenase Kinase Regulates Mitochondrial Activity in Cancer Cells ⬇️

scientific article published on December 23, 2011

Flux balance analysis predicts essential genes in clear cell renal cell carcinoma metabolism

scientific article

Functional metabolic screen identifies 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 as an important regulator of prostate cancer cell survival.

scientific article

Functional screening identifies MCT4 as a key regulator of breast cancer cell metabolism and survival

scientific article published on 12 May 2015

Genetic ablation of S6-kinase does not prevent processing of SREBP1

scientific article published on 18 November 2010

Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling

scientific article published on January 2013

Glycolysis back in the limelight: systemic targeting of HK2 blocks tumor growth

scientific article published on October 2013

Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development

scientific article

How cancer metabolism is tuned for proliferation and vulnerable to disruption ⬇️

scientific article published on November 15, 2012

Induction of Mxi1-SR alpha by FOXO3a contributes to repression of Myc-dependent gene expression

scientific article

Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells

scientific article published in December 2005

LXRα activation and Raf inhibition trigger lethal lipotoxicity in liver cancer

scientific article published in 2021

Linking Glycogen and Senescence in Cancer Cells ⬇️

scientific article published on 01 December 2012

Lipid desaturation - the next step in targeting lipogenesis in cancer?

scientific article published on 16 February 2016

Lipid metabolism in cancer

scientific article published on 03 July 2012

Metabotypes of breast cancer cell lines revealed by non-targeted metabolomics

scientific article published on 27 December 2016

Mevalonate Pathway Provides Ubiquinone to Maintain Pyrimidine Synthesis and Survival in p53-Deficient Cancer Cells Exposed to Metabolic Stress

scientific article published on 19 November 2019

MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer

scientific article published on 20 August 2021

Modulation of cellular migration and survival by c-Myc through the downregulation of urokinase (uPA) and uPA receptor

scientific article

NFATc1 controls the cytotoxicity of CD8+ T cells

scientific article published on 11 September 2017

Navigating gene expression using microarrays--a technology review

scientific article

Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways.

scientific article

PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP.

scientific article published in September 2005

Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells

scientific article

Regulation of Metabolic Activity by p53.

scientific article

Regulation of cyclin E gene expression by the human papillomavirus type 16 E7 oncoprotein.

scientific article published on August 1999

Regulation of the SREBP transcription factors by mTORC1.

scientific article published on April 2011

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

scientific article

SREBP maintains lipid biosynthesis and viability of cancer cells under lipid- and oxygen-deprived conditions and defines a gene signature associated with poor survival in glioblastoma multiforme

scientific article published on 26 January 2015

Systematic Analysis Reveals that Cancer Mutations Converge on Deregulated Metabolism of Arachidonate and Xenobiotics

scientific article published on 5 July 2016

Targeting cancer metabolism--aiming at a tumour's sweet-spot

scientific article published on 22 December 2011

The Role of Glucose and Lipid Metabolism in Growth and Survival of Cancer Cells

scientific article

The big picture: exploring the metabolic cross-talk in cancer

The forkhead transcription factor FOXO3a increases phosphoinositide-3 kinase/Akt activity in drug-resistant leukemic cells through induction of PIK3CA expression

scientific article published on 21 July 2008

The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma

scientific article published on 05 June 2018

The kinase PKD3 provides negative feedback on cholesterol and triglyceride synthesis by suppressing insulin signaling

scientific article published on 06 August 2019

The multifaceted roles of fatty acid synthesis in cancer

scientific article (publication date: 23 September 2016)

The transcriptional response to Raf activation is almost completely dependent on Mitogen-activated Protein Kinase Kinase activity and shows a major autocrine component

scientific article published on 16 April 2004

mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism

scientific article published in 2024

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