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List of works by R. John Collier

2001: a year of major advances in anthrax toxin research

scientific article

A dually active anthrax vaccine that confers protection against both bacilli and toxins

scientific article

A hybrid toxin containing fragment A from diphtheria toxin linked to the B protomer of cholera toxin

scientific article published on December 1980

A loop network within the anthrax toxin pore positions the phenylalanine clamp in an active conformation

scholarly article

A monoclonal antibody to Bacillus anthracis protective antigen defines a neutralizing epitope in domain 1

scientific article

A phenylalanine clamp catalyzes protein translocation through the anthrax toxin pore

scientific article published on July 2005

A quantitative study of the interactions of Bacillus anthracis edema factor and lethal factor with activated protective antigen

scientific journal article

A semisynthesis platform for investigating structure-function relationships in the N-terminal domain of the anthrax Lethal Factor

scientific article published on April 2010

A soluble receptor decoy protects rats against anthrax lethal toxin challenge

scientific article published on 10 August 2005

Acid-induced unfolding of the amino-terminal domains of the lethal and edema factors of anthrax toxin

scientific article

Active-Site Mutations of Diphtheria Toxin: Role of Tyrosine-65 in NAD Binding and ADP-Ribosylation

scientific article published on 01 December 1994

Active-site mutations of diphtheria toxin: effects of replacing glutamic acid-148 with aspartic acid, glutamine, or serine

scientific article

Active-site mutations of the diphtheria toxin catalytic domain: role of histidine-21 in nicotinamide adenine dinucleotide binding and ADP-ribosylation of elongation factor 2.

scientific article

Amino acid residues involved in membrane insertion and pore formation of Clostridium botulinum C2 toxin

scientific article published on 18 July 2008

Amino acid sequence homology between the enzymic domains of diphtheria toxin and Pseudomonas aeruginosa exotoxin A.

scientific article published in March 1988

An approach to characterizing single-subunit mutations in multimeric prepores and pores of anthrax protective antigen

scientific article published on February 2009

Anthrax Toxin

article

Anthrax Toxin as a Molecular Tool for Stimulation of Cytotoxic T Lymphocytes: Disulfide-Linked Epitopes, Multiple Injections, and Role of CD4+Cells ⬇️

scientific article published on October 1, 1998

Anthrax Toxin-Mediated Delivery In Vivo and In Vitro of a Cytotoxic T-Lymphocyte Epitope from Ovalbumin ⬇️

scientific article published on February 1, 1998

Anthrax delivers a lethal blow to host immunity

scientific article published in August 2003

Anthrax lethal toxin induces cell death-independent permeability in zebrafish vasculature

scientific article

Anthrax protective antigen interacts with a specific receptor on the surface of CHO-K1 cells

scientific article published on October 1991

Anthrax protective antigen: efficiency of translocation is independent of the number of ligands bound to the prepore

scientific article

Anthrax protective antigen: prepore-to-pore conversion

scientific article

Anthrax toxin complexes: heptameric protective antigen can bind lethal factor and edema factor simultaneously

scientific article

Anthrax toxin entry into polarized epithelial cells

scientific article

Anthrax toxin receptor 2 determinants that dictate the pH threshold of toxin pore formation

scientific article

Anthrax toxin receptor 2-dependent lethal toxin killing in vivo

scientific journal article

Anthrax toxin-mediated delivery of a cytotoxic T-cell epitope in vivo

scientific article published on October 1996

Anthrax toxin: channel-forming activity of protective antigen in planar phospholipid bilayers

scientific article

Anthrax toxin: receptor binding, internalization, pore formation, and translocation

scientific article published on January 2007

Antibiotic-based selection for bacterial genes that are specifically induced during infection of a host

scientific article

Antibody-directed cytotoxic agents: use of monoclonal antibody to direct the action of toxin A chains to colorectal carcinoma cells

scientific article

Antiinflammatory cAMP signaling and cell migration genes co-opted by the anthrax bacillus

scholarly article

Assembly and disassembly kinetics of anthrax toxin complexes

scientific article published on February 2006

Assembly of anthrax toxin pore: lethal-factor complexes into lipid nanodiscs

scientific article

Association of polyomavirus middle tumor antigen with 14-3-3 proteins

scientific article published on July 1994

Binding of transfer factor II to ribosomal RNA and inhibition of the binding by guanosine nucleotides

scientific article

Binding stoichiometry and kinetics of the interaction of a human anthrax toxin receptor, CMG2, with protective antigen

scientific article

Biochemical and physiological changes induced by anthrax lethal toxin in J774 macrophage-like cells ⬇️

scientific article published on November 1, 1992

Characterization of membrane translocation by anthrax protective antigen

scientific article published on November 1998

Chemical dissection of protein translocation through the anthrax toxin pore

scientific article published on 3 February 2011

Circular dichroism of diphtheria toxin, Pseudomonas aeruginosa exotoxin A, and various derivatives

scientific article

Combining anthrax vaccine and therapy: a dominant-negative inhibitor of anthrax toxin is also a potent and safe immunogen for vaccines

scientific article

Conformation of the diphtheria toxin T domain in membranes: a site-directed spin-labeling study of the TH8 helix and TL5 loop

scientific article published on August 1999

Conformational integrity of a recombinant toxoid of Pseudomonas aeruginosa exotoxin A containing a deletion of glutamic acid-553

scientific article published on 01 February 1992

Conformational switching of the diphtheria toxin T domain

scientific article published on 21 July 2010

Correction: Anthrax Toxin Receptor 2–Dependent Lethal Toxin Killing In Vivo

scientific article

Cross-linked forms of the isolated N-terminal domain of the lethal factor are potent inhibitors of anthrax toxin

scientific article published on 16 July 2007

Crystal structure of the anthrax lethal factor

scientific article

Crystal structure of the anthrax toxin protective antigen

scientific article

Crystal structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptor

scientific article

Crystal structure of the zeta isoform of the 14-3-3 protein ⬇️

scientific article published on July 13, 1995

Crystallization of exotoxin A from Pseudomonas aeruginosa

scientific article published on 01 May 1982

Crystallographic studies of the anthrax lethal toxin

scientific article

Cys-Cys cross-linking shows contact between the N-terminus of lethal factor and Phe427 of the anthrax toxin pore

scientific article published on 6 April 2011

Cytotoxic T-lymphocyte epitopes fused to anthrax toxin induce protective antiviral immunity

scientific article published on July 1999

DNA fragmentation and cytolysis in U937 cells treated with diphtheria toxin or other inhibitors of protein synthesis

scientific article published on September 1993

Designing a polyvalent inhibitor of anthrax toxin

scientific article

Differences in the immunogenicity of native and formalinized cross reacting material (CRM197) of diphtheria toxin in mice and guinea pigs and their implications on the development and control of diphtheria vaccine based on CRMs.

scientific article

Diphthamide synthesis in Saccharomyces cerevisiae: structure of the DPH2 gene.

scientific article

Diphtheria toxin: quantification and assay

scientific article published in January 1988

Disulfide bonds in the ectodomain of anthrax toxin receptor 2 are required for the receptor-bound protective-antigen pore to function

scientific article

Dominant-Negative Mutants of a Toxin Subunit: An Approach to Therapy of Anthrax

scientific article published in Science

Effect of 2-fluorohistidine labeling of the anthrax protective antigen on stability, pore formation, and translocation

scientific article published on 29 November 2007

Effect of Anthrax Toxin's Lethal Factor on Ion Channels Formed by the Protective Antigen

scientific article published in Journal of Biological Chemistry

Effects of Mutations in Proline 345 on Insertion of Diphtheria Toxin into Model Membranes

article

Effects of dynamin inactivation on pathways of anthrax toxin uptake

scientific article published in July 2004

Effects of introducing a single charged residue into the phenylalanine clamp of multimeric anthrax protective antigen

scientific article

Evidence for a proton-protein symport mechanism in the anthrax toxin channel

scientific article published on 09 February 2009

Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin I

scientific article

Evidence that translocation of anthrax toxin's lethal factor is initiated by entry of its N terminus into the protective antigen channel

scholarly article

Exchange characteristics of calcium ions bound to anthrax protective antigen

scientific article published in January 2003

Expression of a mutant, full-length form of diphtheria toxin in Escherichia coli.

scientific article published on July 1987

Expression of the S-1 catalytic subunit of pertussis toxin in Escherichia coli.

scientific article published on May 1987

Fluorescence resonance energy transfer studies on anthrax lethal toxin

scientific article published in August 2003

Functions of phenylalanine residues within the beta-barrel stem of the anthrax toxin pore

scientific article

Fused polycationic peptide mediates delivery of diphtheria toxin A chain to the cytosol in the presence of anthrax protective antigen

scientific article published on August 1996

GroEL as a molecular scaffold for structural analysis of the anthrax toxin pore.

scientific article

Identification of novel host-targeted compounds that protect from anthrax lethal toxin-induced cell death

scientific article published on 4 February 2013

Identification of residues lining the anthrax protective antigen channel

scientific article

Identification of the cellular receptor for anthrax toxin

scientific article (publication date: 8 November 2001)

Imaging the cell entry of the anthrax oedema and lethal toxins with fluorescent protein chimeras

scientific article published in October 2010

Inhibition of axotomy-induced neuronal apoptosis by extracellular delivery of a Bcl-XL fusion protein

scientific article (publication date: 7 December 2001)

Insertion of Anthrax Protective Antigen into Liposomal Membranes

scientific article published in Journal of Biological Chemistry

Interaction of Diphtheria Toxin T Domain with Molten Globule-Like Proteins and Its Implications for Translocation

scientific article published in Science

Interaction of the 20 kDa and 63 kDa fragments of anthrax protective antigen: kinetics and thermodynamics

scientific article published in January 2005

Interaction of the protein kinase Raf-1 with 14-3-3 proteins

scientific article

Interaction of transferase II with the 60 s ribosomal subunit.

scientific article published in May 1971

Interactions of anthrax lethal factor with protective antigen defined by site-directed spin labeling

scientific article

Involvement of domain 3 in oligomerization by the protective antigen moiety of anthrax toxin

scientific article

Locating a residue in the diphtheria toxin channel ⬇️

scientific article published on April 1, 1992

Mapping dominant-negative mutations of anthrax protective antigen by scanning mutagenesis

scientific article

Mapping the anthrax protective antigen binding site on the lethal and edema factors

scientific article published on 19 November 2001

Mapping the lethal factor and edema factor binding sites on oligomeric anthrax protective antigen

scientific article

Membrane Topography of the T Domain of Diphtheria Toxin Probed with Single Tryptophan Mutants†

article

Membrane Translocation of Charged Residues at the Tips of Hydrophobic Helices in the T Domain of Diphtheria Toxin†

article

Membrane insertion by anthrax protective antigen in cultured cells

scientific article

Membrane translocation and channel-forming activities of diphtheria toxin are blocked by replacing isoleucine 364 with lysine ⬇️

scientific article published on May 1, 1993

Membrane translocation by anthrax toxin

scientific article published on 27 June 2009

Monitoring the kinetics of the pH-driven transition of the anthrax toxin prepore to the pore by biolayer interferometry and surface plasmon resonance

scientific article

Mutant anthrax toxin B moiety (protective antigen) inhibits angiogenesis and tumor growth

scientific article published in October 2007

Mutational analysis of the helical hairpin region of diphtheria toxin transmembrane domain

scientific article published on September 1994

NAD binding site of diphtheria toxin: identification of a residue within the nicotinamide subsite by photochemical modification with NAD ⬇️

scientific article published on June 1, 1984

On the role of macrophages in anthrax

scientific article published on November 1993

Organization of diphtheria toxin T domain in bilayers: a site-directed spin labeling study

scientific article

PA63 channel of anthrax toxin: an extended beta-barrel

scientific article

Participation of lysine 516 and phenylalanine 530 of diphtheria toxin in receptor recognition.

scientific article published in November 1994

Phenylalanine-427 of anthrax protective antigen functions in both pore formation and protein translocation

scholarly article

Photoaffinity Labeling of Diphtheria Toxin Fragment A with 8-Azidoadenosyl Nicotinamide Adenine Dinucleotide†

scientific article published on 01 October 1999

Photoaffinity labeling of active site residues in ADP-ribosylating toxins

scientific article published on January 1994

Photoaffinity labeling of diphtheria toxin fragment A with NAD: structure of the photoproduct at position 148.

scientific article

Photolabeling of Glu-129 of the S-1 subunit of pertussis toxin with NAD.

scientific article

Point mutations in anthrax protective antigen that block translocation

scientific article

Polylysine-mediated translocation of the diphtheria toxin catalytic domain through the anthrax protective antigen pore

scientific article

Preclinical evaluation of group B streptococcal polysaccharide conjugate vaccines prepared with a modified diphtheria toxin and a recombinant duck hepatitis B core antigen

scientific article published on 01 November 2001

Probing the structure of the diphtheria toxin channel. Reactivity in planar lipid bilayer membranes of cysteine-substituted mutant channels with methanethiosulfonate derivatives

scientific article

Protective antigen-binding domain of anthrax lethal factor mediates translocation of a heterologous protein fused to its amino- or carboxy-terminus

article

Protein Translocation through the Anthrax Toxin Transmembrane Pore is Driven by a Proton Gradient

article

Protein translocation through anthrax toxin channels formed in planar lipid bilayers

scientific article

Proteolytic activation of receptor-bound anthrax protective antigen on macrophages promotes its internalization

scientific article

Reaction of diphtheria toxin channels with sulfhydryl-specific reagents: observation of chemical reactions at the single molecule level.

scientific article

Receptor-directed chimeric toxins created by sortase-mediated protein fusion

scientific article published on 14 August 2013

Receptor-specific requirements for anthrax toxin delivery into cells

scientific article

Refined crystallographic structure of Pseudomonas aeruginosa exotoxin A and its implications for the molecular mechanism of toxicity

scientific article

Replacement of C-terminal histidines uncouples membrane insertion and translocation in diphtheria toxin T-domain

scientific article published on 15 November 2011

Reversible refolding of the diphtheria toxin T-domain on lipid membranes

scientific article

Reversion of recombinant toxoids: mutations in diphtheria toxin that partially compensate for active-site deletions

scientific article

Role of CypA and Hsp90 in membrane translocation mediated by anthrax protective antigen

scientific article

Role of glutamic acid 988 of human poly-ADP-ribose polymerase in polymer formation. Evidence for active site similarities to the ADP-ribosylating toxins

scientific article published on February 1995

Role of macrophage oxidative burst in the action of anthrax lethal toxin.

scientific article

Roles of Glu 349 and Asp 352 in membrane insertion and translocation by diphtheria toxin

scientific article published on April 1996

Solubilization and characterization of the anthrax toxin pore in detergent micelles

scientific article

Stoichiometry of anthrax toxin complexes

scientific article

Structural Determinants for the Binding of Anthrax Lethal Factor to Oligomeric Protective Antigen

scientific article published in Journal of Biological Chemistry

Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution

scientific article

Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation

scientific article

Structure of the isolated catalytic domain of diphtheria toxin

scientific article

Structure-function relationships in diphtheria toxin channels: I. Determining a minimal channel-forming domain

scientific article published on 01 January 1994

Targeting HER2-positive cancer cells with receptor-redirected anthrax protective antigen

scientific article

The crystal structure of diphtheria toxin

scientific article

The diphtheria toxin channel-forming T domain translocates its own NH2-terminal region across planar bilayers

scientific article

The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen

scientific article

The mechanism of ADP-ribosylation of elongation factor 2 catalyzed by fragment A from diphtheria toxin

scientific article published on August 1977

The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor

scientific article

Three dimensional structure of the anthrax toxin translocon-lethal factor complex by cryo-electron microscopy

scientific article published on 18 March 2013

Three-dimensional structure of the anthrax toxin pore inserted into lipid nanodiscs and lipid vesicles

scientific article

Topography of diphtheria Toxin's T domain in the open channel state

scientific article

Translocation of the catalytic domain of diphtheria toxin across planar phospholipid bilayers by its own T domain

scientific article published on July 1999

Ultrasensitive detection of protein translocated through toxin pores in droplet-interface bilayers

scientific article

Understanding the mode of action of diphtheria toxin: a perspective on progress during the 20th century

scientific article

Whole-cell voltage clamp measurements of anthrax toxin pore current

scientific article published on 23 September 2005

pH-dependent insertion of proteins into membranes: B-chain mutation of diphtheria toxin that inhibits membrane translocation, Glu-349----Lys

scientific article

pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes.

scientific article

pH-dependent permeabilization of the plasma membrane of mammalian cells by anthrax protective antigen

article

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