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List of works by Per Svenningsson

5-HT1B receptor imaging and cognition: a positron emission tomography study in control subjects and Parkinson's disease patients

scientific article published on 25 May 2015

A role for p11 in the antidepressant action of brain-derived neurotrophic factor

scientific article

A twelve-year follow-up study on a case of early-onset parkinsonism preceding clinical manifestation of Gaucher disease

scientific article published on 20 September 2011

Abstract # 1792 Peripheral inflammatory mediators and p11 levels in peripheral blood mononuclear cells from patients with Parkinson’s disease

scholarly article by H.F. Green et al published October 2016 in Brain, Behavior, and Immunity

Activation of adenosine A2A and dopamine D1 receptors stimulates cyclic AMP-dependent phosphorylation of DARPP-32 in distinct populations of striatal projection neurons

scientific article published in May 1998

Activation of dopamine D2 receptors decreases DARPP-32 phosphorylation in striatonigral and striatopallidal projection neurons via different mechanisms

scientific article published in January 1999

Adenosine and brain function

scientific article

Alterations in 5-HT1B receptor function by p11 in depression-like states

scientific article

Alterations of p11 in brain tissue and peripheral blood leukocytes in Parkinson's disease

scientific article published on 30 January 2017

An automated method for scanning LC-MS data sets for significant peptides and proteins, including quantitative profiling and interactive confirmation

scientific article

Antagonism of adenosine A2A receptors underlies the behavioural activating effect of caffeine and is associated with reduced expression of messenger RNA for NGFI-A and NGFI-B in caudate-putamen and nucleus accumbens

scientific article

Antidepressant-like properties of sarizotan in experimental Parkinsonism

scientific article

Antidepressants reverse the attenuation of the neurotrophic MEK/MAPK cascade in frontal cortex by elevated platform stress; reversal of effects on LTP is associated with GluA1 phosphorylation

scientific article published on 9 July 2008

Asymmetric dopaminergic degeneration and levodopa alter functional corticostriatal connectivity bilaterally in experimental parkinsonism

scientific article published on 18 February 2017

Attenuated beta rebound to proprioceptive afferent feedback in Parkinson's disease

scholarly article published 30 May 2018

Behavioral and biochemical responses to d-amphetamine in MCH1 receptor knockout mice

scientific article published in February 2008

Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11.

scientific article published on 02 October 2012

Caffeine mimics the effect of a dopamine D2/3 receptor agonist on the expression of immediate early genes in globus pallidus

scientific article published in September 1997

Caveolin-1 interacts with alpha-synuclein and mediates toxic actions of cellular alpha-synuclein overexpression

scientific article

Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs

scientific article published on 11 July 2008

Cell- and region-specific expression of depression-related protein p11 (S100a10) in the brain

scientific article published on 12 September 2016

Cellular distribution of adenosine A2A receptor mRNA in the primate striatum

scientific article published in September 1998

Cellular localization and function of DARPP-32 in the rodent retina

scientific article published on June 2007

Changes on 5-HT2 receptor mRNAs in striatum and subthalamic nucleus in Parkinson's disease model

scientific article published on 21 May 2007

Clinical and genetic characteristics of late-onset Huntington's disease

scientific article

Clozapine counteracts a ketamine-induced depression of hippocampal-prefrontal neuroplasticity and alters signaling pathway phosphorylation

scientific article

Co-expression of serotonin 5-HT(1B) and 5-HT(4) receptors in p11 containing cells in cerebral cortex, hippocampus, caudate-putamen and cerebellum

scientific article published on 12 February 2011

Controlled-pH tissue cleanup protocol for signal enhancement of small molecule drugs analyzed by MALDI-MS imaging

scientific article

Correlations Between Methionine Cycle Metabolism, COMT Genotype, and Polyneuropathy in L-Dopa Treated Parkinson's Disease: A Preliminary Cross-Sectional Study

scientific article

Coupling surface plasmon resonance to mass spectrometry to discover novel protein-protein interactions

scientific article published on 11 June 2009

Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum

scientific journal article

DARPP-32 Mediates the Actions of Multiple Drugs of Abuse

DARPP-32 mediates serotonergic neurotransmission in the forebrain

scientific article

DARPP-32 mediates the actions of multiple drugs of abuse

scientific article

DARPP-32: an integrator of neurotransmission

scientific article published on January 2004

Decreased Prosaposin and Progranulin in the Cingulate Cortex Are Associated with Schizophrenia Pathophysiology

scientific article published in 2022

Decreased striatal levels of PEP-19 following MPTP lesion in the mouse

scientific article published in February 2006

Depressive-like phenotype induced by AAV-mediated overexpression of human α-synuclein in midbrain dopaminergic neurons

scientific article published on 9 September 2015

Deuterated matrix-assisted laser desorption ionization matrix uncovers masked mass spectrometry imaging signals of small molecules

scientific article

Diffusion tensor fiber tractography of the olfactory tract ⬇️

scientific article published on September 17, 2010

Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity

scientific article published in July 2006

Distribution of adenosine receptors in the postmortem human brain: an extended autoradiographic study

scientific article published in December 1997

Distribution, biochemistry and function of striatal adenosine A2A receptors

scientific article

Distribution, level, pharmacology, regulation, and signaling of 5‐HT6 receptors in rats and marmosets with special reference to an experimental model of parkinsonism ⬇️

scientific article published on June 15, 2011

Diverse psychotomimetics act through a common signaling pathway

scientific article

Dopamine D(1) receptor-induced gene transcription is modulated by DARPP-32

scientific journal article

Dopamine-adenosine interactions in the striatum and the globus pallidus: inhibition of striatopallidal neurons through either D2 or A2A receptors enhances D1 receptor-mediated effects on c-fos expression.

scientific article published in October 1997

Effect of methylphenidate on dopamine/DARPP signalling in adult, but not young, mice

scientific article

Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease

scientific article published in July 2015

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

scientific article

Effects of lithium and aripiprazole on brain stimulation reward and neuroplasticity markers in the limbic forebrain.

scientific article published on 8 November 2013

Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson's disease: a dose-finding study

scientific article

Emotional memory impairments in a genetic rat model of depression: involvement of 5-HT/MEK/Arc signaling in restoration

scientific article published on 18 January 2011

Emotional memory impairments induced by AAV-mediated overexpression of human α-synuclein in dopaminergic neurons of the ventral tegmental area

scientific article published on September 2015

Epigenetics and energetics in ventral hippocampus mediate rapid antidepressant action: Implications for treatment resistance

scientific article published on 27 June 2016

Estradiol affects spinophilin protein differently in gonadectomized males and females

scientific article published on January 2004

Evidence for a role of the 5-HT1B receptor and its adaptor protein, p11, in L-DOPA treatment of an animal model of Parkinsonism

scholarly article

Evidence that the increase in striatal c-fos following acute high-dose caffeine is not due to direct interaction with striatal adenosine receptors

scientific article published in December 1992

Feasibility Aspects of Exploring Exercise-Induced Neuroplasticity in Parkinson's Disease: A Pilot Randomized Controlled Trial

scientific article published on 25 March 2020

Folding Underlies Bidirectional Role of GPR37/Pael-R in Parkinson Disease

scientific article

Functional GPR37 trafficking protects against toxicity induced by 6-OHDA, MPP+ or rotenone in a catecholaminergic cell line

scientific article

GPR37 protein trafficking to the plasma membrane regulated by prosaposin and GM1 gangliosides promotes cell viability

scientific article published on 26 December 2013

Gene therapy blockade of dorsal striatal p11 improves motor function and dyskinesia in parkinsonian mice

scientific article published on 19 January 2016

Genetic Variations and mRNA Expression of NRF2 in Parkinson's Disease

scientific article

Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia

scientific article published on 28 March 2017

Heat stabilization of the tissue proteome: a new technology for improved proteomics

scientific article

How can drug discovery for psychiatric disorders be improved?

scientific article published in March 2007

Identification of protein-protein interactions by surface plasmon resonance followed by mass spectrometry

scientific article published in August 2011

In search of the mechanisms of ketamine’s antidepressant effects: How robust is the evidence behind the mTor activation hypothesis

Increased expression of NGFI-A mRNA in the rat striatum following burst stimulation of the medial forebrain bundle

scientific article published in November 1997

Increased expression of c-jun, junB, AP-1, and preproenkephalin mRNA in rat striatum following a single injection of caffeine.

scientific article published on May 1995

Increased levels of ubiquitin in the 6-OHDA-lesioned striatum of rats

scientific article

Increased striatal mRNA and protein levels of the immunophilin FKBP-12 in experimental Parkinson's disease and identification of FKBP-12-binding proteins

scientific journal article

Involvement of AMPA receptor phosphorylation in antidepressant actions with special reference to tianeptine

scientific article

Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine

scientific article published in August 2002

Involvement of a c-fos-dependent mechanism in caffeine-induced expression of the preprotachykinin A and neurotensin/neuromedin N genes in rat striatum

scientific article published in October 1997

Involvement of striatal and extrastriatal DARPP-32 in biochemical and behavioral effects of fluoxetine (Prozac).

scientific article

Lurasidone and fluoxetine reduce novelty-induced hypophagia and NMDA receptor subunit and PSD-95 expression in mouse brain

scientific article published on 20 July 2015

MRI Diffusion in Parkinson's Disease: Using the Technique's Inherent Directional Information to Study the Olfactory Bulb and Substantia Nigra ⬇️

scientific article published on January 1, 2012

Mass Spectrometry Imaging, an Emerging Technology in Neuropsychopharmacology ⬇️

scientific article published on August 21, 2013

Methylenedioxymethamphetamine (MDMA)

article

Modulation of monoamine receptors by adaptor proteins and lipid rafts: role in some effects of centrally acting drugs and therapeutic agents

scientific article published on January 2011

Molecular profiling of experimental Parkinson's disease: direct analysis of peptides and proteins on brain tissue sections by MALDI mass spectrometry

scientific article published in March 2004

Monoamines, BDNF, IL-6 and corticosterone in CSF in patients with Parkinson's disease and major depression

scientific article published on 21 October 2009

Mu- and delta-opioid receptor agonists inhibit DARPP-32 phosphorylation in distinct populations of striatal projection neurons

scientific article published in June 1999

NMDA receptor antagonists ketamine and Ro25-6981 inhibit evoked release of glutamate in vivo in the subiculum

scientific article published on 3 June 2014

Neurogenic effects of fluoxetine are attenuated in p11 (S100A10) knockout mice

scientific article published on 15 March 2010

Neurokinin B/NK3 receptors exert feedback inhibition on L-DOPA actions in the 6-OHDA lesion rat model of Parkinson's disease

scientific article published on 18 March 2008

Neuropeptide Y and Calcitonin Gene-Related Peptide in Cerebrospinal Fluid in Parkinson's Disease with Comorbid Depression versus Patients with Major Depressive Disorder

scientific article

Neuropeptidomics of mouse hypothalamus after imipramine treatment reveal somatostatin as a potential mediator of antidepressant effects

scientific article

Neuropeptidomics: MS applied to the discovery of novel peptides from the brain

scientific article

Nigrostriatal dopamine transporter availability in early Parkinson's disease

scientific article published on 13 February 2018

No correlation between serotonin and its metabolite 5-HIAA in the cerebrospinal fluid and [(11) C]AZ10419369 binding measured with PET in healthy volunteers

scientific article published on 9 July 2014

Novel Imaging Biomarkers for Huntington's Disease and Other Hereditary Choreas

scientific article published on 5 October 2018

Novel Treatment Opportunities Against Cognitive Impairment in Parkinson's Disease with an Emphasis on Diabetes-Related Pathways

scientific article published on 01 February 2019

Optimal Acquisition Time Window and Simplified Quantification of Dopamine Transporter Availability Using 18F-FE-PE2I in Healthy Controls and Parkinson Disease Patients

scientific article published on 26 May 2016

Overexpression of α-synuclein simultaneously increases glutamate NMDA receptor phosphorylation and reduces glucocerebrosidase activity

scientific article published on 20 November 2015

P.1.006 Neurogenic and chronic behavioural effects of fluoxetine are attenuated in p11 KO mice

P.2.b.019 Ablated neurogenic response to fluoxetine in female p11 knockout mice

P11 deficiency increases stress reactivity along with HPA axis and autonomic hyperresponsiveness

scientific article published on 01 October 2020

Peptidomics-Based Discovery of Novel Neuropeptides ⬇️

scientific article published on March 1, 2003

Phactrs 1-4: A family of protein phosphatase 1 and actin regulatory proteins

scientific article

Pharmacological or genetic blockade of the dopamine D3 receptor increases cell proliferation in the hippocampus of adult mice

scientific article published on 10 October 2012

Phosphorylation of DARPP-32 at Threonine-34 is required for cocaine action

scientific article

Positron emission tomography imaging of 5-hydroxytryptamine1B receptors in Parkinson's disease

scientific article published on 12 October 2013

Protection of stress-induced impairment of hippocampal/prefrontal LTP through blockade of glucocorticoid receptors: implication of MEK signaling

scientific article published on 16 March 2008

Quantitative Analysis of ¹⁸F-(E)-N-(3-Iodoprop-2-Enyl)-2β-Carbofluoroethoxy-3β-(4'-Methyl-Phenyl) Nortropane Binding to the Dopamine Transporter in Parkinson Disease

scientific article published on 19 March 2015

Quantitative mapping shows that serotonin rather than dopamine receptor mRNA expressions are affected after repeated intermittent administration of MDMA in rat brain

scientific article published on 3 July 2006

Reduced phosphorylation of GluA1 subunits relates to anxiety-like behaviours in mice

scientific article published on 29 January 2013

Regional differences in the ability of caffeine to affect haloperidol-induced striatal c-fos mRNA expression in the rat.

scientific article published in January 1998

Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum

scientific article

Regulation of serotonin receptor function in the nervous system by lipid rafts and adaptor proteins

scientific article published on 06 March 2010

Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptors

scientific article published on February 2000

Repeated l-DOPA treatment increases c-fos and BDNF mRNAs in the subthalamic nucleus in the 6-OHDA rat model of Parkinson's disease

scientific article published on 24 May 2006

Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens

scientific article

Ropinirole regulates emotionality and neuronal activity markers in the limbic forebrain

scientific article

S100B interacts with the serotonin 5-HT7 receptor to regulate a depressive-like behavior

scientific article published on 20 October 2015

S100B overexpressing mutant mice exhibit prolonged behavioural and biochemical responses towards repeated intermittent binge treatments with MDMA.

scientific article published on 24 September 2008

S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent. II. A neurochemical, electrophysiologic

scientific article published on 16 November 2007

Safety and tolerability of IRL790 in Parkinson's disease with levodopa-induced dyskinesia-a phase 1b trial

scholarly article by Per Svenningsson et al published 2018 in NPJ Parkinson's disease

Safety and tolerability of intracerebroventricular PDGF-BB in Parkinson's disease patients

scientific article

Serotonin-1A receptors in major depression quantified using PET: Controversies, confounds, and recommendations ⬇️

scientific article (publication date: 15 February 2012)

Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice

scientific article published on June 2000

Striatal adenosine A2A receptors--where are they? What do they do?

scientific article published in February 1998

Striatal alterations of secretogranin-1, somatostatin, prodynorphin, and cholecystokinin peptides in an experimental mouse model of Parkinson disease

scientific article published on 08 January 2009

Strong association between glucocerebrosidase mutations and Parkinson's disease in Sweden

scientific article published on 03 May 2016

Studies of depression-related states in animal models of Parkinsonism

scientific article published on January 2012

The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology

scientific journal article

The role of DARPP-32 in the actions of drugs of abuse

scientific article published in January 2004

The significance of biochemical and molecular sample integrity in brain proteomics and peptidomics: stathmin 2-20 and peptides as sample quality indicators

scientific article published on December 2007

The stimulatory action and the development of tolerance to caffeine is associated with alterations in gene expression in specific brain regions.

scientific article published in May 1999

Tianeptine potentiates AMPA receptors by activating CaMKII and PKA via the p38, p42/44 MAPK and JNK pathways

scientific article published on 25 October 2011

Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons

scientific article

Use of surface plasmon resonance coupled with mass spectrometry reveals an interaction between the voltage-gated sodium channel type X alpha-subunit and caveolin-1.

scientific article published in December 2008

p11 (S100A10)--an inducible adaptor protein that modulates neuronal functions

scientific article published on 7 November 2006

p11 and its role in depression and therapeutic responses to antidepressants

scientific article published on October 2013

p11 modulates L-DOPA therapeutic effects and dyskinesia via distinct cell types in experimental Parkinsonism

scientific article published on 19 January 2016

α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter

scientific article

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