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List of works by Nicholas Jarvis Proudfoot

20 years of making messenger RNA ⬇️

scientific article published on 01 November 1997

A beginning to the biochemistry of polyadenylation

scientific article

A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expression

scientific article

A role for chromatin remodeling in transcriptional termination by RNA polymerase II.

scientific article

A sequence downstream of AAUAAA is required for rabbit β-globin mRNA 3′-end formation

scientific article published in Nature

A single-base change at a splice site in a beta 0-thalassemic gene causes abnormal RNA splicing

scientific article published in July 1982

AT-rich sequence elements promote nascent transcript cleavage leading to RNA polymerase II termination

scientific article published on 20 December 2012

Adenylation and exosome-mediated degradation of cotranscriptionally cleaved pre-messenger RNA in human cells

scientific article

Alpha-thalassaemia caused by a polyadenylation signal mutation.

scientific article

An ungracious host for an unwelcome guest

scientific article published on 01 August 2008

Autoregulation of TDP-43 mRNA levels involves interplay between transcription, splicing, and alternative polyA site selection.

scientific article

Autoregulation of convergent RNAi genes in fission yeast.

scientific article

BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair

scientific article

Balancing transcriptional interference and initiation on the GAL7 promoter of Saccharomyces cerevisiae

scientific article published on July 2000

Biosynthesis of histone messenger RNA employs a specific 3' end endonuclease

scientific article published on 03 December 2018

Characterization of beta-globin mRNA in the beta0 thalassemias

scientific article published on 01 June 1978

Cleavage/polyadenylation factor IA associates with the carboxyl-terminal domain of RNA polymerase II in Saccharomyces cerevisiae.

scholarly article

Co-transcriptional RNA cleavage provides a failsafe termination mechanism for yeast RNA polymerase I.

scientific article published on 23 October 2010

Complete 3' noncoding region sequences of rabbit and human beta-globin messenger RNAs

scientific article

Connecting transcription to messenger RNA processing

scientific article

Convergent transcription induces transcriptional gene silencing in fission yeast and mammalian cells.

scientific article published on 30 September 2012

Coupled RNA processing and transcription of intergenic primary microRNAs

scientific article published on 10 August 2009

Coupling termination of transcription to messenger RNA maturation in yeast.

scientific article published in April 1998

Dawdling polymerases allow introns time to splice

scientific article published on 01 November 2003

Definition of RNA polymerase II CoTC terminator elements in the human genome.

scientific article published on 4 April 2013

Definition of transcriptional promoters in the human beta globin locus control region

scientific article published on 01 November 2002

Dicer-dependent turnover of intergenic transcripts from the human beta-globin gene cluster

scientific article published on November 2005

Disengaging polymerase: terminating RNA polymerase II transcription in budding yeast

scientific article

Drosha Regulates Gene Expression Independently of RNA Cleavage Function

scientific article published on 12 June 2014

Drosha regulates gene expression independently of RNA cleavage function.

scientific article published on 19 December 2013

Dynamic interactions between the promoter and terminator regions of the mammalian BRCA1 gene

scholarly article

EM visualization of transcription by RNA polymerase II: downstream termination requires a poly(A) signal but not transcript cleavage.

scientific article

Ending the message is not so simple

scientific article

Ending the message: poly(A) signals then and now

scientific article

Expression of the early lymphocyte activation antigen CD69, a C-type lectin, is regulated by mRNA degradation associated with AU-rich sequence motifs

scientific article published on 01 August 1995

Fail-safe transcriptional termination for protein-coding genes in S. cerevisiae.

scientific article

Feed backwards model for microRNA processing and splicing in plants.

scientific article published on 14 June 2013

Gene Silencing CUTs Both Ways

article

Genome-wide analysis of poly(A) site selection in Schizosaccharomyces pombe

scientific article published on 23 October 2013

Globin gene monkey business

scientific article published on 01 June 1986

Histone 3 s10 phosphorylation: "caught in the R loop!".

scientific article

Homologous gene sequences mediate transcription-domain formation

scientific article published on 29 August 2006

How RNA polymerase II terminates transcription in higher eukaryotes

scientific article published on March 1989

Human 5' --> 3' exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites

scientific article

Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination

scientific article

Human nuclear Dicer restricts the deleterious accumulation of endogenous double-stranded RNA.

scientific article

Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination

scientific article

Integrating mRNA processing with transcription

scientific journal article

Intergenic transcription in the human beta-globin gene cluster

scientific article published on October 2001

Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II.

scientific article published in November 2003

Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing

scientific article

Mammalian NET-Seq Reveals Genome-wide Nascent Transcription Coupled to RNA Processing

scientific article

Mammalian NET-seq analysis defines nascent RNA profiles and associated RNA processing genome-wide

scientific article published on 4 February 2016

Mitochondrial double-stranded RNA triggers antiviral signalling in humans

scientific article published in Nature

Modulating alternative splicing by cotranscriptional cleavage of nascent intronic RNA.

scientific article published on 7 December 2007

Molecular dissection of mammalian RNA polymerase II transcriptional termination

scientific article published on March 2008

Multiple transcript cleavage precedes polymerase release in termination by RNA polymerase II

scientific article (publication date: June 2001)

Nascent transcription from the nmt1 and nmt2 genes of Schizosaccharomyces pombe overlaps neighbouring genes.

scientific article

Nuclear fate of yeast snoRNA is determined by co-transcriptional Rnt1 cleavage

scientific article

Nuclear roadblocks for mRNA export

scientific article published on 01 October 2008

Nucleotide sequence of the 3' terminal third of rabbit alpha-globin messenger RNA: comparison with human alpha-globin messenger RNA.

scientific article

Pause sites promote transcriptional termination of mammalian RNA polymerase II

scientific article

Pcf11 orchestrates transcription termination pathways in yeast

scientific article published on 15 April 2015

Poly(A) signals control both transcriptional termination and initiation between the tandem GAL10 and GAL7 genes of Saccharomyces cerevisiae ⬇️

scientific article published on August 17, 1998

Poly(A) signals.

scientific article

Polyadenylation: a tail of two complexes.

scientific article

Polypyrimidine tract binding protein modulates efficiency of polyadenylation.

scientific article published on May 2004

Position-dependent sequence elements downstream of AAUAAA are required for efficient rabbit beta-globin mRNA 3' end formation

scientific article published on 01 May 1987

Post-transcriptional regulation. Chasing your own poly(A) tail

scientific article published on 01 April 1994

Primary microRNA transcripts are processed co-transcriptionally.

scientific article

R-loop formation during S phase is restricted by PrimPol-mediated repriming

scientific article published on 26 November 2018

R-loop stabilization represses antisense transcription at the Arabidopsis FLC locus.

scientific article published on May 2013

R-loops induce repressive chromatin marks over mammalian gene terminators

scientific article published on 5 October 2014

RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination

scientific article published on 3 May 2018

RNA Polymerase II Phosphorylated on CTD Serine 5 Interacts with the Spliceosome during Co-transcriptional Splicing

scholarly article by Takayuki Nojima published in October 2018

RNA polymerase I in yeast transcribes dynamic nucleosomal rDNA.

scientific article

RNA polymerase II kinetics in polo polyadenylation signal selection.

scientific article

Rad51, friend or foe?

scientific article published on 11 June 2013

Recruitment of a basal polyadenylation factor by the upstream sequence element of the human lamin B2 polyadenylation signal.

scientific article

Regulation of elongating RNA polymerase II by forkhead transcription factors in yeast

scientific article

Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase I

scientific article

SCAF4 and SCAF8, mRNA Anti-Terminator Proteins

scientific article published on 16 May 2019

Sequence analysis of eukaryotic mRNA.

scientific article

Sequence analysis of immunoglobulin light chain messenger RNA ⬇️

scientific article published on November 29, 1974

Sequence analysis of the 3' non-coding regions of rabbit alpha- and beta-globin messenger RNAs

scientific article published on November 1976

Silencing in trans: position matters in fission yeast.

scientific article published on 12 February 2010

Sp1 functions in a chromatin-dependent manner to augment human alpha-globin promoter activity ⬇️

scientific article published on August 1, 1995

Specific transcriptional pausing activates polyadenylation in a coupled in vitro system

scientific article

Stem-loop 1 of the U1 snRNP plays a critical role in the suppression of HIV-1 polyadenylation.

scientific article published in February 2000

Strong polyadenylation and weak pausing combine to cause efficient termination of transcription in the human Ggamma-globin gene.

scientific article published on April 2005

Structure and in Vitro Transcription of Human Globin Genes ⬇️

scientific article published on September 19, 1980

Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II

scientific article published on 01 March 1999

Terminate and make a loop: regulation of transcriptional directionality

scientific article

Terminating transcription in yeast: whether to be a 'nerd' or a 'rat'

scientific article published on 01 August 2008

The 3' terminal sequences of human alpha and beta globin messenger RNAs: comparison with rabbit globin messenger RNA.

scientific article published in December 1976

The HIV-1 5' LTR poly(A) site is inactivated by U1 snRNP interaction with the downstream major splice donor site.

scientific article published on September 1997

The end of the message

scientific article published in Nature

The retroviruses human immunodeficiency virus type 1 and Moloney murine leukemia virus adopt radically different strategies to regulate promoter-proximal polyadenylation.

scientific article published on December 2001

The structure and evolution of the human beta-globin gene family

scientific article (publication date: October 1980)

The structure of the human zeta-globin gene and a closely linked, nearly identical pseudogene

scientific article

Transcription and polyadenylation in a short human intergenic region.

scientific article published on June 1997

Transcription termination between polo and snap, two closely spaced tandem genes of D. melanogaster.

scientific article published on July 2012

Transcriptional Interference and Gene Orientation in Yeast: Noncoding RNA Connections ⬇️

scientific article published on January 1, 2010

Transcriptional Termination Enhances Protein Expression in Human Cells

scientific article published on 4 February 2016

Transcriptional activation of the general amino acid permease gene per1 by the histone deacetylase Clr6 Is regulated by Oca2 kinase

scientific article

Transcriptional collision between convergent genes in budding yeast.

scientific article

Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter.

scientific article published on March 1998

Transcriptional termination by RNA polymerase I requires the small subunit Rpa12p.

scientific article

Transcriptional termination enhances protein expression in human cells

scientific article published on February 2009

Transcriptional termination factors for RNA polymerase II in yeast

scientific article published on 01 May 2001

Transcriptional termination sequences in the mouse serum albumin gene.

scientific article published in April 2006

Transcriptional termination signals for RNA polymerase II in fission yeast ⬇️

scientific article published on June 16, 1997

Turnover and function of noncoding RNA polymerase II transcripts.

scientific article published on January 2006

Yeast Sen1 helicase protects the genome from transcription-associated instability.

scientific article

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