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List of works by Michael Henry Malim

A Plea for Justice for Jailed Medical Workers

scientific article published in Science

A highly conserved RNA folding region coincident with the Rev response element of primate immunodeficiency viruses

scientific article published in March 1990

A sensitive, quantitative assay for human immunodeficiency virus type 1 integration

scientific article published on November 2002

A triple-arginine motif in the amino-terminal domain and oligomerization are required for HIV-1 inhibition by human MX2

scientific article published on 11 February 2015

APOBEC proteins and intrinsic resistance to HIV-1 infection

scientific article published on March 2009

APOBEC restriction goes nuclear

scientific article published on 01 January 2019

APOBEC-mediated editing of viral RNA.

scientific article published on July 2004

APOBEC-mediated interference with hepadnavirus production

scientific article published in August 2005

APOBEC-mediated viral restriction: not simply editing?

scientific article published on 15 February 2007

APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G

scientific article

APOBEC3G inhibits elongation of HIV-1 reverse transcripts

scientific article

Ability of the V3 loop of simian immunodeficiency virus to serve as a target for antibody-mediated neutralization: correlation of neutralization sensitivity, growth in macrophages, and decreased dependence on CD4

scientific article

Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events.

scientific article

Antiviral function of APOBEC3G can be dissociated from cytidine deaminase activity

scientific article published in January 2005

Antiviral potency of APOBEC proteins does not correlate with cytidine deamination

scientific article published on September 2006

Antiviral protein APOBEC3G localizes to ribonucleoprotein complexes found in P bodies and stress granules

scientific article

Author Correction: The interferon-inducible isoform of NCOA7 inhibits endosome-mediated viral entry

scientific article published on 01 March 2019

Biochemical analyses of the interactions between human immunodeficiency virus type 1 Vpr and p6(Gag).

scientific article published on November 2001

ChAdOx1 nCoV-19 vaccine elicits monoclonal antibodies with cross-neutralizing activity against SARS-CoV-2 viral variants

scientific article published on 15 April 2022

Characterization of the alpha interferon-induced postentry block to HIV-1 infection in primary human macrophages and T cells

scientific article

Comparative assessment of multiple COVID-19 serological technologies supports continued evaluation of point-of-care lateral flow assays in hospital and community healthcare settings

scientific article published on 24 September 2020

Comparison of cellular ribonucleoprotein complexes associated with the APOBEC3F and APOBEC3G antiviral proteins

scientific article

Complex Interplay between HIV-1 Capsid and MX2-Independent Alpha Interferon-Induced Antiviral Factors

scientific article published on 8 June 2016

Comprehensive investigation of the molecular defect in vif-deficient human immunodeficiency virus type 1 virions

scientific article

Cytidine deamination of retroviral DNA by diverse APOBEC proteins

scientific journal article

DNA deamination mediates innate immunity to retroviral infection

scientific article (publication date: 13 June 2003)

Deep sequencing of HIV-1 reverse transcripts reveals the multifaceted antiviral functions of APOBEC3G.

scientific article published on 20 November 2017

Defining APOBEC3 expression patterns in human tissues and hematopoietic cell subsets

scientific article published on 08 July 2009

Determinants of syncytium formation in microglia by human immunodeficiency virus type 1: role of the V1/V2 domains

scientific article

Determining 3'-Termini and Sequences of Nascent Single-Stranded Viral DNA Molecules during HIV-1 Reverse Transcription in Infected Cells

scientific article published on 30 January 2019

Drug repurposing based on a quantum-inspired method versus classical fingerprinting uncovers potential antivirals against SARS-CoV-2

scientific article published on 18 July 2022

Effects of Inner Nuclear Membrane Proteins SUN1/UNC-84A and SUN2/UNC-84B on the Early Steps of HIV-1 Infection.

scientific article

Endogenous MOV10 inhibits the retrotransposition of endogenous retroelements but not the replication of exogenous retroviruses

scientific article

Evidence for IFNα-induced, SAMHD1-independent inhibitors of early HIV-1 infection

scientific article published on 25 February 2013

Evidence for a newly discovered cellular anti-HIV-1 phenotype

scientific article

Evolution of a species-specific determinant within human CRM1 that regulates the post-transcriptional phases of HIV-1 replication

scientific article (publication date: November 2011)

Expression strategies of the yeast retrotransposon Ty: a short sequence directs ribosomal frameshifting

scientific article

Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev function

article

Further investigation of simian immunodeficiency virus Vif function in human cells

scientific article

Gold nanoparticle-mediated gene delivery induces widespread changes in the expression of innate immunity genes.

scientific article published on 23 June 2011

Guidelines for naming nonprimate APOBEC3 genes and proteins

scientific article

HIV Interplay with SAMHD1

scientific article published in Science

HIV Restriction Factors and Mechanisms of Evasion

scientific article published in May 2012

HIV-1 Replication and APOBEC3 Antiviral Activity Are Not Regulated by P Bodies ⬇️

scientific article published on August 22, 2012

HIV-1 Vpr Induces Widespread Transcriptomic Changes in CD4<sup>+</sup> T Cells Early Postinfection

scientific article published on 22 June 2021

HIV-1 and interferons: who's interfering with whom?

scientific article

HIV-1 infection of non-dividing cells: evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import.

scientific article

HIV-1 infection requires a functional integrase NLS.

scientific article published in May 2001

HIV-1 regulatory/accessory genes: keys to unraveling viral and host cell biology

scientific article published in June 1998

HIV-1 sequence variation: drift, shift, and attenuation

scientific article

HIV: Ringside views

scientific article published on January 2014

Hepatitis B virus DNA is subject to extensive editing by the human deaminase APOBEC3C.

scientific article

Heteromeric interactions regulate butyrophilin (BTN) and BTN-like molecules governing γδ T cell biology

scientific article published on 16 January 2018

How Representative Are Research Tissue Biobanks of the Local Populations? Experience of the Infectious Diseases Biobank at King's College, London, UK

scientific article

Human APOBEC3 induced mutation of human immunodeficiency virus type-1 contributes to adaptation and evolution in natural infection

scientific article

Human APOBEC3G-mediated editing can promote HIV-1 sequence diversification and accelerate adaptation to selective pressure

scientific article

Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

scientific article

Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding

scientific article published on November 2000

Identification of amino acid residues in APOBEC3G required for regulation by human immunodeficiency virus type 1 Vif and Virion encapsidation

scientific article

Immune evasion activities of accessory proteins Vpu, Nef and Vif are conserved in acute and chronic HIV-1 infection.

scientific article published on 30 March 2015

Immunoproteasome activation enables human TRIM5α restriction of HIV-1

scientific article published on 18 March 2019

In vivo attenuation of simian immunodeficiency virus by disruption of a tyrosine-dependent sorting signal in the envelope glycoprotein cytoplasmic tail

scientific article

Increasing best practice data sharing at PLOS Pathogens

scientific article published in 2021

Insight into the HIV-1 Vif SOCS-box-ElonginBC interaction

scientific article

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

scientific article (publication date: 8 August 2002)

Kinetics of Early Innate Immune Activation during HIV-1 Infection of Humanized Mice

scientific article published on 15 May 2019

Long HIV type 1 reverse transcripts can accumulate stably within resting CD4+ T cells while short ones are degraded

scientific article published on March 2004

Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans

scientific article published on 26 October 2020

MX2-mediated innate immunity against HIV-1 is regulated by serine phosphorylation

scientific article published on 19 July 2021

Matrix mediates the functional link between human immunodeficiency virus type 1 RNA nuclear export elements and the assembly competency of Gag in murine cells.

scientific article

Multiple components of the nuclear pore complex interact with the amino-terminus of MX2 to facilitate HIV-1 restriction

article

Natural resistance to HIV infection: The Vif–APOBEC interaction

article

Nef protein of human immunodeficiency virus type 1: evidence against its role as a transcriptional inhibitor

scientific article

New insights into an X-traordinary viral protein

scientific article published in 2014

Nuclear export of human immunodeficiency virus type 1 Vpr is not required for virion packaging

scientific article published on September 2001

Nuclear import of SAMHD1 is mediated by a classical karyopherin α/β1 dependent pathway and confers sensitivity to VpxMAC induced ubiquitination and proteasomal degradation

scientific article

Oligomerization Requirements for MX2-Mediated Suppression of HIV-1 Infection

scientific article

Pan-cancer transcriptomic analysis dissects immune and proliferative functions of APOBEC3 cytidine deaminases

scientific article published on 01 February 2019

Peripheral immunophenotypes in children with multisystem inflammatory syndrome associated with SARS-CoV-2 infection

scientific article published on 18 August 2020

Persistent HIV-1 replication maintains the tissue reservoir during therapy

scientific article published on 27 January 2016

Pharmacological cyclin-dependent kinase inhibitors inhibit replication of wild-type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus type 1 by targeting cellular, not viral, proteins

scientific article

Promiscuous RNA binding ensures effective encapsidation of APOBEC3 proteins by HIV-1.

scientific article

RNA-dependent oligomerization of APOBEC3G is required for restriction of HIV-1

scientific article

Rationalisation of the differences between APOBEC3G structures from crystallography and NMR studies by molecular dynamics simulations

scientific article

Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import

scientific article

Resilient SARS-CoV-2 diagnostics workflows including viral heat inactivation

scientific article published on 28 April 2020

Retroviral mRNA nuclear export elements regulate protein function and virion assembly.

scientific article published on 17 June 2004

Retrovirus RNA trafficking: from chromatin to invasive genomes

scientific article published on 19 September 2006

Rev-mediated nuclear export of RNA is dominant over nuclear retention and is coupled to the Ran-GTPase cycle.

scientific article published on November 1999

Reverse transcriptase activity and Ty RNA are associated with virus-like particles in yeast

scientific article

SRp40 and SRp55 promote the translation of unspliced human immunodeficiency virus type 1 RNA

scientific article

Secreted placental alkaline phosphatase as a eukaryotic reporter gene

scientific article published on January 1992

Sequence requirements for Rev multimerization in vivo

scientific article published on July 1994

SnapShot: HIV-1 Proteins

article

Suppression of HIV-1 infection by APOBEC3 proteins in primary human CD4(+) T cells is associated with inhibition of processive reverse transcription as well as excessive cytidine deamination

scientific article published on 14 November 2012

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

scientific article published on September 1997

TRIM5 alpha cytoplasmic bodies are highly dynamic structures

scientific article

Target cell-mediated editing of HIV-1 cDNA by APOBEC3 proteins in human macrophages.

scientific article published on 28 September 2011

The GTPase Domain of MX2 Interacts with the HIV-1 Capsid, Enabling Its Short Isoform to Moderate Antiviral Restriction

scientific article published on 01 November 2019

The HIV-1 Rev protein: prototype of a novel class of eukaryotic post-transcriptional regulators

scientific article published on September 1991

The SOCS-box of HIV-1 Vif interacts with ElonginBC by induced-folding to recruit its Cul5-containing ubiquitin ligase complex

scientific article

The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif ⬇️

scientific article (publication date: November 2003)

The innate antiviral factor APOBEC3G targets replication of measles, mumps and respiratory syncytial viruses

scientific article

The interferon-inducible isoform of NCOA7 inhibits endosome-mediated viral entry

scientific article published on 26 November 2018

The production of hybrid Ty:IFN virus-like particles in yeast

scientific article

The regulation of primate immunodeficiency virus infectivity by Vif is cell species restricted: a role for Vif in determining virus host range and cross-species transmission

scientific article published on August 1998

Transfer of the amino-terminal nuclear envelope targeting domain of human MX2 converts MX1 into an HIV-1 resistance factor

scientific article

Translational Research in the Time of COVID-19-Dissolving Boundaries

scientific article published on 30 September 2020

Unsung Hero Robert C. Gallo

scientific article

Unusual polymorphisms in human immunodeficiency virus type 1 associated with nonprogressive infection

scientific article

Virion incorporation of human immunodeficiency virus type-1 Vif is determined by intracellular expression level and may not be necessary for function

scientific article published on September 1998

cis Expression of DC-SIGN allows for more efficient entry of human and simian immunodeficiency viruses via CD4 and a coreceptor

scientific article

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