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List of works by Michael Harvey Hastings

A Gq-Ca2+ axis controls circuit-level encoding of circadian time in the suprachiasmatic nucleus.

scientific article published on 25 April 2013

A clockwork web: circadian timing in brain and periphery, in health and disease

scientific article (publication date: August 2003)

A diversity of paracrine signals sustains molecular circadian cycling in suprachiasmatic nucleus circuits.

scientific article

A dual-immunocytochemical method to localize c-fos protein in specific neurons based on their content of neuropeptides and connectivity

scientific article

A nonphotic stimulus causes instantaneous phase advances of the light-entrainable circadian oscillator of the Syrian hamster but does not induce the expression of c-fos in the suprachiasmatic nuclei

scientific article published in July 1992

A novel form of pigment-dispersing hormone in the central nervous system of the intertidal marine isopod, Eurydice pulchra (leach).

scientific article published in February 2011

A role for the circadian clock of the suprachiasmatic nuclei in the interpretation of serial melatonin signals in the Syrian hamster

scientific article published in December 1996

A spatio-temporal model to reveal oscillator phenotypes in molecular clocks: Parameter estimation elucidates circadian gene transcription dynamics in single-cells

scientific article published on 17 December 2021

A specific role for the REV-ERBα-controlled L-Type Voltage-Gated Calcium Channel CaV1.2 in resetting the circadian clock in the late night

scientific article

A thalamic contribution to arousal-induced, non-photic entrainment of the circadian clock of the Syrian hamster

scientific article published in August 1997

Analysis of circadian mechanisms in the suprachiasmatic nucleus by transgenesis and biolistic transfection

scientific article published in January 2005

Analysis of clock proteins in mouse SCN demonstrates phylogenetic divergence of the circadian clockwork and resetting mechanisms

scientific article published on 01 February 2000

Analysis of core circadian feedback loop in suprachiasmatic nucleus of mCry1-luc transgenic reporter mouse

scientific article

Astrocytes Control Circadian Timekeeping in the Suprachiasmatic Nucleus via Glutamatergic Signaling.

scientific article published on 08 March 2017

Behavioural and cellular responses to light of the circadian system of tau mutant and wild-type Syrian hamsters

scientific article published on 01 March 1995

Blockade of Glutamatergic Neurotransmission in the Suprachiasmatic Nucleus Prevents Cellular and Behavioural Responses of the Circadian System to Light

scientific article published on 01 January 1992

Brain aromatization of testosterone in the male Syrian hamster: effects of androgen and photoperiod

scientific article published on 01 February 1991

CREB in the mouse SCN: a molecular interface coding the phase-adjusting stimuli light, glutamate, PACAP, and melatonin for clockwork access.

scientific article published in December 1998

Catabolic cytokines disrupt the circadian clock and the expression of clock-controlled genes in cartilage via an NFкB-dependent pathway.

scientific article

Cell-autonomous clock of astrocytes drives circadian behavior in mammals.

scientific article published in January 2019

Cellular circadian pacemaking and the role of cytosolic rhythms

scientific article published on September 2008

Cellular mechanisms of circadian pacemaking: beyond transcriptional loops

scientific article published on January 2013

Central clocking ⬇️

scientific article published on October 1, 1997

Changes in photoperiod alter the daily rhythms of pineal melatonin content and hypothalamic beta-endorphin content and the luteinizing hormone response to naloxone in the male Syrian hamster

scientific article published in July 1985

Circadian Clocks: Timely Interference by MicroRNAs

scientific article published on 01 September 2007

Circadian and daily rhythms of melatonin in the blood and pineal gland of free-running and entrained Syrian hamsters

scientific article published in January 1993

Circadian and photoperiodic time measurement in male Syrian hamsters following lesions of the melatonin-binding sites of the paraventricular thalamus

scientific article published in January 1992

Circadian clocks and neurodegenerative diseases: time to aggregate?

scientific article published on 21 June 2013

Circadian clocks.

scientific article published on November 1997

Circadian clocks: genes, sleep, and cognition

scientific article published on 24 April 2010

Circadian clocks: neural and peripheral pacemakers that impact upon the cell division cycle

scientific article

Circadian clocks: self-assembling oscillators?

scientific article

Circadian clockwork: two loops are better than one.

scientific article

Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus

scientific article published in April 2002

Circadian factor BMAL1 in histaminergic neurons regulates sleep architecture

scientific article published on 13 November 2014

Circadian orchestration of the hepatic proteome

scientific article

Circadian pacemaking in cells and circuits of the suprachiasmatic nucleus.

scientific article

Circadian rhythms: a gut feeling for time

scientific article published in May 2002

Circadian timing in health and disease

scientific article published on January 2006

Class IIa histone deacetylases are conserved regulators of circadian function.

scientific article published on 30 September 2014

Combined Pharmacological and Genetic Manipulations Unlock Unprecedented Temporal Elasticity and Reveal Phase-Specific Modulation of the Molecular Circadian Clock of the Mouse Suprachiasmatic Nucleus.

scientific article published on September 2016

Cycle of period gene expression in a diurnal mammal (Spermophilus tridecemlineatus): implications for nonphotic phase shifting

scientific article

Cyclic AMP Signaling Control of Action Potential Firing Rate and Molecular Circadian Pacemaking in the Suprachiasmatic Nucleus

scientific article published on 01 June 2011

Decrease of food intake by MC4-R agonist MTII in Siberian hamsters in long and short photoperiods

scientific article published on 27 September 2002

Developmental and reproductive performance in circadian mutant mice.

scientific article

Differential adrenergic regulation of the circadian expression of the clock genes Period1 and Period2 in the rat pineal gland

scientific article published in December 2000

Differential contributions of intra-cellular and inter-cellular mechanisms to the spatial and temporal architecture of the suprachiasmatic nucleus circadian circuitry in wild-type, cryptochrome-null and vasoactive intestinal peptide receptor 2-null m

scientific article published on 02 June 2014

Differential effects of photoperiodic history on the responses of gonadotrophins and prolactin to intermediate daylengths in the male Syrian hamster

scientific article published on 01 January 1989

Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock

scientific journal article

Differential regulation of mPER1 and mTIM proteins in the mouse suprachiasmatic nuclei: new insights into a core clock mechanism.

scientific article

Differential resynchronisation of circadian clock gene expression within the suprachiasmatic nuclei of mice subjected to experimental jet lag.

scientific article published in September 2002

Disintegration of the sleep-wake cycle and circadian timing in Huntington's disease.

scientific article published in January 2005

Disrupted circadian rhythms in a mouse model of schizophrenia.

scientific article

Disruption of peripheral circadian timekeeping in a mouse model of Huntington's disease and its restoration by temporally scheduled feeding

scientific article published in July 2010

Dissociation of circadian and circatidal timekeeping in the marine crustacean Eurydice pulchra.

scientific article published on 26 September 2013

Distinct and separable roles for endogenous CRY1 and CRY2 within the circadian molecular clockwork of the suprachiasmatic nucleus, as revealed by the Fbxl3(Afh) mutation.

scientific article

Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking.

scientific article published on 22 February 2016

Effect of asymmetrical reductions of photoperiod on pineal melatonin, locomotor activity and gonadal condition of male Syrian hamsters

scientific article published in August 1987

Effects of Ibotenic Acid-Induced Neuronal Degeneration in the Hypothalamus upon Proceptivity and Sexual Receptivity in the Female Marmoset (Callithrix jacchus)

scientific article published on 01 December 1992

Effects of N-methyl-D-aspartate (NMDA) on seasonal cycles of reproduction, body weight and pelage colour in the male Siberian hamster.

scientific article published on July 1995

Effects of chronic jet lag on tumor progression in mice.

scientific article published in November 2004

Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

scientific article

Entrainment of the circadian clock.

scientific article

Entrainment of the circadian system of mammals by nonphotic cues

scientific article published in September 1998

Entrainment to feeding but not to light: circadian phenotype of VPAC2 receptor-null mice.

scientific article

Expression of clock gene products in the suprachiasmatic nucleus in relation to circadian behaviour.

scientific article published on January 2003

Expression of mCLOCK and other circadian clock-relevant proteins in the mouse suprachiasmatic nuclei

scientific article published in April 2003

Feeding and behavioural effects of central administration of the melanocortin 3/4-R antagonist SHU9119 in obese and lean Siberian hamsters

scientific article published in July 2004

FosB in the Suprachiasmatic Nucleus of the Syrian and Siberian Hamster

scientific article published on 01 January 1996

Gating of retinal inputs through the suprachiasmatic nucleus: role of excitatory neurotransmission

scientific article published in September 1995

Generation of circadian rhythms in the suprachiasmatic nucleus

scientific article published on 01 August 2018

Genetic analysis of circadian responses to low frequency electromagnetic fields in Drosophila melanogaster.

scientific article

Genetic code expansion in the mouse brain

scientific article published on 29 August 2016

Glucocorticoid signaling synchronizes the liver circadian transcriptome

scientific article published on 01 June 2007

Glutamatergic induction of CREB phosphorylation and Fos expression in primary cultures of the suprachiasmatic hypothalamus in vitro is mediated by co-ordinate activity of NMDA and non-NMDA receptors

scientific article

Gonadal responses of the male tau mutant Syrian hamster to short-day-like programmed infusions of melatonin

scientific article published on 01 August 1995

Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour

scientific journal article

Hibernation proteins: preparing for life in the freezer

scientific article published on 01 April 2006

Host circadian clock as a control point in tumor progression.

scientific article published in May 2002

Immediate-early genes and the neural bases of photic and non-photic entrainment.

scientific article

Impaired expression of the mPer2 circadian clock gene in the suprachiasmatic nuclei of aging mice

scientific article published on 01 May 2001

Increased coherence of circadian rhythms in mature fibroblast cultures

scientific article published on December 2008

Interacting molecular loops in the mammalian circadian clock

scientific article (publication date: 12 May 2000)

Interactions entre mutation des gènes horloge, phénotype circadien et croissance tumorale chez la Souris

article

Intra-hypothalamic melatonin blocks photoperiodic responsiveness in the male Syrian hamster

scientific article

Intracellular signalling in the ovine pars tuberalis: an investigation using aluminium fluoride and melatonin.

scientific article published on October 1991

Investigation into the regulation of the circadian system by dopamine and melatonin in the adult Siberian hamster (Phodopus sungorus).

scientific article published in November 1998

Labeling and identifying cell-specific proteomes in the mouse brain.

scientific article published on 18 December 2017

Lesions of the iodomelatonin-binding sites of the mediobasal hypothalamus spare the lactotropic, but block the gonadotropic response of male Syrian hamsters to short photoperiod and to melatonin

scientific article published in January 1995

Lesions of the melatonin- and androgen-responsive tissue of the dorsomedial nucleus of the hypothalamus block the gonadal response of male Syrian hamsters to programmed infusions of melatonin.

scientific article

Melatonin Inhibits the Activation of Cyclic AMP-Dependent Protein Kinase in Cultured Pars Tuberalis Cells from Ovine Pituitary

scientific article

Melatonin Receptor Sites in the Syrian Hamster Brain and Pituitary. Localization and Characterization Using [|]lodomelatonin*.

scientific article

Melatonin and the brain in photoperiodic mammals.

scientific article published in January 1985

Melatonin receptors in the rat brain and pituitary

scientific article published on 01 November 1995

Melatonin regulates the phosphorylation of CREB in ovine pars tuberalis.

scientific article published on October 1994

Melatonin-sensitive, serum-stimulated signalling in ovine pars tuberalis

scientific article published in May 1997

Metabolic molecular markers of the tidal clock in the marine crustacean Eurydice pulchra.

scientific article published on April 2015

Metabolic regulation: fasting in the dark.

scientific article published in April 2006

Minireview: The circadian clockwork of the suprachiasmatic nuclei--analysis of a cellular oscillator that drives endocrine rhythms

scientific article published on 27 September 2007

Modifications to the hand-held Gene Gun: improvements for in vitro biolistic transfection of organotypic neuronal tissue

scientific article

Naloxone-induced secretion of LH in the male Syrian hamster: modulation by photoperiod and gonadal steroids

scientific article published in August 1985

Neuroendocrine rhythms.

scientific article published on January 1991

Neurotoxic amino acid lesions of the lateral hypothalamus: a parametric comparison of the effects of ibotenate, N-methyl-D,L-aspartate and quisqualate in the rat.

scientific article published in December 1985

Neurotoxic lesions of the anterior hypothalamus disrupt the photoperiodic but not the circadian system of the Syrian hamster

scientific article published in April 1985

Neurotoxic lesions of the paraventriculo-spinal projection block the nocturnal rise in pineal melatonin synthesis in the Syrian hamster

scientific article

Neurotrophic effects of BDNF on embryonic gonadotropin-releasing hormone (GnRH) neurons.

scientific article

Non-photic circadian entrainment in the Syrian hamster is not associated with phosphorylation of the transcriptional regulator CREB within the suprachiasmatic nucleus, but is associated with adrenocortical activation

scientific article

Non-photic phase shifting of the circadian activity rhythm of Syrian hamsters: the relative potency of arousal and melatonin

scientific article published on September 18, 1992

Non-photic signalling in the suprachiasmatic nucleus

scientific article published in November 1997

Occlusion of the melatonin-free interval blocks the short day gonadal response of the male Syrian hamster to programmed melatonin infusions of necessary duration and amplitude.

scientific article

Opposing actions of neuropeptide Y and light on the expression of circadian clock genes in the mouse suprachiasmatic nuclei

scientific article published in January 2002

Peroxiredoxins are conserved markers of circadian rhythms

scientific article

Persistent twenty-four hour changes in liver and bone marrow despite suprachiasmatic nuclei ablation in mice.

scientific article

Pharmacological imposition of sleep slows cognitive decline and reverses dysregulation of circadian gene expression in a transgenic mouse model of Huntington's disease.

scientific article

Phospholipases and melatonin signal transduction in the ovine pars tuberalis

scientific article

Phosphorylation of CREB in ovine pars tuberalis is regulated both by cyclic AMP-dependent and cyclic AMP-independent mechanisms

scientific article published in August 1996

Photoperiod regulates the LH response to central glutamatergic stimulation in the male Syrian hamster

scientific article published on 01 December 1993

Photoperiodic influences on sexual behavior in male Syrian hamsters

scientific article published on 01 January 1989

Photoperiodic regulation of glutamatergic stimulation of secretion of luteinizing hormone in male Syrian hamsters

scientific article published on August 1, 1992

Photoperiodically induced changes in glutamatergic stimulation of LH secretion in male Syrian hamsters: role of circulating testosterone and endogenous opioids

scientific article published on 01 October 1994

Physiology. A looser clock to cure jet lag

scientific article published on 01 October 2013

Production of a prolactin releasing factor by the ovine pars tuberalis

scientific article published in July 1996

Prokineticin receptor 2 (Prokr2) is essential for the regulation of circadian behavior by the suprachiasmatic nuclei.

scholarly article

Prolonged exposure to melatonin leads to time-dependent sensitization of adenylate cyclase and down-regulates melatonin receptors in pars tuberalis cells from ovine pituitary ⬇️

scientific article published on January 1, 1993

Proteomic analysis reveals the role of synaptic vesicle cycling in sustaining the suprachiasmatic circadian clock

scientific article published on 12 November 2009

Rapid resetting of the mammalian circadian clock

scientific article

Re-assembled botulinum neurotoxin inhibits CNS functions without systemic toxicity

scientific article published on 24 March 2011

Regional distribution of iodomelatonin binding sites within the suprachiasmatic nucleus of the Syrian hamster and the Siberian hamster

scientific article published on 01 March 1995

Regulating the Suprachiasmatic Nucleus (SCN) Circadian Clockwork: Interplay between Cell-Autonomous and Circuit-Level Mechanisms.

scientific article published on 3 January 2017

Regulation of alternative splicing by the circadian clock and food related cues

scientific article

Regulation of mitogen-activated protein kinase in the pars tuberalis of the ovine pituitary: interactions between melatonin, insulin-like growth factor-1, and forskolin

scientific article published on 01 January 1996

Resistance of gonadotropin-releasing hormone neurons to glutamatergic neurotoxicity.

scientific article published in December 1998

Rhythmic expression of cryptochrome induces the circadian clock of arrhythmic suprachiasmatic nuclei through arginine vasopressin signaling

scientific article published on 22 February 2016

Serotonergic antagonists impair arousal-induced phase shifts of the circadian system of the syrian hamster

scientific article published in February 1996

Setting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins

scientific article

Signaling role of prokineticin 2 on the estrous cycle of female mice

scientific article

Single-cell transcriptomics of suprachiasmatic nuclei reveal a Prokineticin-driven circadian network

scientific article published on 06 September 2021

Some reflections on the phylogeny and function of the pineal.

scientific article

Stimuli which entrain the circadian clock of the neonatal Syrian hamster in vivo regulate the phosphorylation of the transcription factor CREB in the suprachiasmatic nucleus in vitro.

scientific article published on March 1998

Synchronization and maintenance of timekeeping in suprachiasmatic circadian clock cells by neuropeptidergic signaling

scientific article published in March 2006

Temporally chimeric mice reveal flexibility of circadian period-setting in the suprachiasmatic nucleus

scientific article published on 10 March 2016

Testicular regression in pinealectomized Syrian hamsters following infusions of melatonin delivered on non-circadian schedules

scientific article published on 01 October 1993

The Regulatory Factor ZFHX3 Modifies Circadian Function in SCN via an AT Motif-Driven Axis

scientific journal article

The Tau mutation of casein kinase 1ε sets the period of the mammalian pacemaker via regulation of Period1 or Period2 clock proteins

scientific article

The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit

scientific article published on 07 July 2020

The VPAC(2) receptor is essential for circadian function in the mouse suprachiasmatic nuclei

scientific article (publication date: 17 May 2002)

The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian period

scientific article

The cell-autonomous clock of VIP receptor VPAC2 cells regulates period and coherence of circadian behaviour

scientific article published on 24 November 2020

The circadian cycle of mPER clock gene products in the suprachiasmatic nucleus of the siberian hamster encodes both daily and seasonal time

scientific article published in August 2000

The effect of signal frequency on the gonadal response of male Syrian hamsters to programmed melatonin infusions

scientific article published on 01 February 1992

The effects of castration, testosterone replacement and photoperiod upon hypothalamic beta-endorphin levels in the male Syrian hamster

scientific article

The hypothalamus and photoperiodic control of FSH secretion by melatonin in the male Syrian hamster.

scientific article published on July 1989

The influence of photoperiod on the hypothalamic content of Beta-endorphin and the luteinizing hormone responses to naloxone and to steroid withdrawal in the male Syrian hamster

scientific article published on 01 October 1991

The inhibitory action of melatonin in the ovine pars tuberalis is not dependent on changes in plasma membrane potential

scientific article published in June 1995

The recovery of ovine pars tuberalis cells from melatonin-induced sensitization is a slow, protein synthesis-dependent phenomenon.

scientific article

The role of N-methyl-d-aspartate-type glutamatergic neurotransmission in the photic induction of immediate-early gene expression in the suprachiasmatic nuclei of the Syrian hamster.

scientific article

The tau mutation in the Syrian hamster alters the photoperiodic responsiveness of the gonadal axis to melatonin signal frequency

scientific article published on 01 May 1996

The tau mutation in the Syrian hamster differentially reprograms the circadian clock in the SCN and peripheral tissues.

scientific article published in April 2005

Tissue-specific abolition of Per1 expression in the pars tuberalis by pinealectomy in the Syrian hamster.

scientific article

Toward a molecular biological calendar?

scientific article

Translational switching of Cry1 protein expression confers reversible control of circadian behavior in arrhythmic Cry-deficient mice

article published in the Proceedings of the National Academy of Sciences of the United States of America

Tuning the period of the mammalian circadian clock: additive and independent effects of CK1εTau and Fbxl3Afh mutations on mouse circadian behavior and molecular pacemaking.

scientific article published in January 2011

Using Actiwatch to monitor circadian rhythm disturbance in Huntington' disease: A cautionary note

scientific article published on 13 January 2016

Vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling

scientific article published in Nature Communications

Visualizing and Quantifying Intracellular Behavior and Abundance of the Core Circadian Clock Protein PERIOD2.

scientific article published on 28 June 2016

cAMP-dependent signaling as a core component of the mammalian circadian pacemaker

scientific article

m(6)A mRNA methylation: a new circadian pacesetter

scientific article

mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop

scientific article (publication date: 23 July 1999)

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