List of works - Jonathan Sprent

A Bacterial Metabolite, Compound K, Induces Programmed Necrosis in MCF-7 Cells via GSK3β.

scientific article published in July 2015

A fundamental role for interleukin-21 in the generation of T follicular helper cells

scientific article

A major histocompatibility complex class I-dependent subset of memory phenotype CD8+ cells

scientific article

A season for midwinter immunology

scientific article published on 01 May 2002

ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes

scientific journal article

Aging leads to disturbed homeostasis of memory phenotype CD8(+) cells

scientific article published on February 2002

An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2

scientific article

Antiviral CD4+ memory T cells are IL-15 dependent

scientific article

Breakdown in repression of IFN-γ mRNA leads to accumulation of self-reactive effector CD8+ T cells

scientific article

CD45-mediated control of TCR tuning in naïve and memory CD8(+) T cells.

scientific article

CD70-CD27 ligation between neural stem cells and CD4+ T cells induces Fas-FasL-mediated T-cell death

scientific article published on 21 May 2013

Calcineurin-dependent negative regulation of CD94/NKG2A expression on naive CD8+ T cells

scientific article published on 03 May 2011

Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}

scholarly article

Cytokines and T cell homeostasis

scientific article

Cytokines and T-cell homeostasis

scientific article published on 12 April 2007

Cytokines and memory-phenotype CD8+ cells.

scientific article

Cytosolic Recognition of RNA Drives the Immune Response to Heterologous Erythrocytes.

scientific article published in November 2017

Dendritic cell internalization of α-galactosylceramide from CD8 T cells induces potent antitumor CD8 T-cell responses

scientific article

Differential Responsiveness of Innate-like IL-17- and IFN-γ-Producing γδ T Cells to Homeostatic Cytokines.

scientific article published on 16 December 2015

Direct stimulation of T cells by membrane vesicles from antigen-presenting cells

scholarly article

Direct stimulation of naïve T cells by antigen-presenting cell vesicles

scientific article

Direct stimulation of naïve T cells by membrane vesicles from antigen-presenting cells: Distinct roles for CD54 and B7 molecules ⬇️

scientific article published on May 12, 2003

Emerging cellular networks for regulation of T follicular helper cells.

scientific article published on 28 December 2011

Ex vivo-expanded DCs induce donor-specific central and peripheral tolerance and prolong the acceptance of donor skin grafts.

scientific article published on 10 January 2011

GM-CSF Culture Revisited: Preparation of Bulk Populations of Highly Pure Dendritic Cells from Mouse Bone Marrow

article

Generation and maintenance of memory CD4(+) T Cells

scientific article published on 11 March 2009

Glimpsing the real CD4+ T cell response.

scientific article published in January 2010

Homeostasis of memory T cells

scientific article published on June 2006

Homeostasis of naive and memory T cells

scientific article published on December 2008

Homeostatic maintenance of T cells and natural killer cells

scientific article published on 30 March 2012

Homeostatic proliferation and survival of naïve and memory T cells

scientific article published on August 2009

IL-2 Shapes the Survival and Plasticity of IL-17-Producing γδ T Cells.

scientific article

IL-2/IL-2Ab complexes induce regulatory T cell expansion and protect against proteinuric CKD.

scientific article

IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25

scientific article

IL-21 contributes to fatal inflammatory disease in the absence of Foxp3+ T regulatory cells.

scientific article published on 20 January 2014

IL-7 regulates basal homeostatic proliferation of antiviral CD4+T cell memory

scholarly article

IL-7/anti-IL-7 mAb complexes restore T cell development and induce homeostatic T Cell expansion without lymphopenia

scientific article published on 01 June 2008

In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression

scientific article published on 30 March 2009

Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells

scientific article

Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells

scientific article published on October 2002

Interleukin 7, maestro of the immune system

scientific article published on 01 May 2012

Interleukin-21 is critically required in autoimmune and allogeneic responses to islet tissue in murine models. ⬇️

scientific article

Is IL-7 from dendritic cells essential for the homeostasis of CD4+ T cells?

scientific article published on 01 July 2010

Knowing one's self: central tolerance revisited

scientific article published on 01 April 2003

Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus

scholarly article

Measurement of T and B cell turnover with bromodeoxyuridine

scientific article

NF-κB2 Controls the Migratory Activity of Memory T Cells by Regulating Expression of CXCR4 in a Mouse Model of Sjögren's Syndrome

scientific article published on 13 August 2017

Normal T cell homeostasis: the conversion of naive cells into memory-phenotype cells

scientific article published on June 2011

On the TRAIL of homeostatic memory T cells

scientific article published on 01 May 2006

Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8+ T cells

scientific article

Phenotypic and Functional Changes of Peripheral Ly6C+ T Regulatory Cells Driven by Conventional Effector T Cells.

scientific article published on 16 March 2018

Potent antitumour activity of interleukin-2-Fc fusion proteins requires Fc-mediated depletion of regulatory T-cells

scientific article

Potential use of IL-2/anti-IL-2 antibody immune complexes for the treatment of cancer and autoimmune disease

scientific article published on December 2006

Proving negative selection in the thymus

scientific article

Re-entry of mature T cells to the thymus: an epiphenomenon?

scientific article published on 02 December 2008

Regulation of mature T cell homeostasis

scientific article

Regulation of naive T cell function by the NF-kappaB2 pathway

scientific article

Regulation of naïve and memory T-cell homeostasis

scientific article

Selective stimulation of T cell subsets with antibody-cytokine immune complexes.

scientific article

Self/non-self discrimination and the problem of keeping T cells alive

scientific article published on 11 December 2007

Simultaneous deletion of MyD88 and Trif delays major histocompatibility and minor antigen mismatch allograft rejection

scientific article published on 01 August 2006

Spontaneous Proliferation of CD4 T Cells in RAG-Deficient Hosts Promotes Antigen-Independent but IL-2-Dependent Strong Proliferative Response of Naïve CD8 T Cells

Staying alive--naïve CD4(+) T cell homeostasis

scientific article

Swapping molecules during cell-cell interactions

scientific article

Systemic human T cell developmental processes in humanized mice cotransplanted with human fetal thymus/liver tissue and hematopoietic stem cells.

scientific article published on December 2012

T cell homeostasis.

scientific article published on 25 March 2008

T cell memory

scientific article

T cell receptor-dependent regulation of lipid rafts controls naive CD8+ T cell homeostasis

scientific article published on 4 February 2010

T cell-B cell collaboration.

scientific article published on 30 May 2017

T memory cells: quality not quantity

scientific article

TCB2, a new anti-human interleukin-2 antibody, facilitates heterodimeric IL-2 receptor signaling and improves anti-tumor immunity

scientific article published on 04 November 2019

TCR tuning of T cell subsets.

scientific article published in May 2018

TGF-β puts the brakes on homeostatic proliferation

scientific article published on 19 June 2012

The Role of Interleukin-2 in Memory CD8 Cell Differentiation ⬇️

scientific article published on January 1, 2010

The lymphopenic environment of CD132 (common gamma-chain)-deficient hosts elicits rapid homeostatic proliferation of naive T cells via IL-15.

scientific article published in April 2008

The majority of murine γδ T cells at the maternal-fetal interface in pregnancy produce IL-17.

scientific article published on 31 May 2016

The power of dilution: using adoptive transfer to study TCR transgenic T cells

scientific article published on 01 December 2013

The role of interleukin-2 during homeostasis and activation of the immune system

scientific article

The thymus and negative selection

scientific article published on 01 July 2002

Turnover of memory-phenotype CD8+ T cells

scientific article

Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

scientific article

Unique features of naive CD8+ T cell activation by IL-2.

scientific article published on 28 October 2013

Writer's block: preventing m6A mRNA methylation promotes T cell naivety

scientific article published on 19 September 2017

List of works by Jonathan Sprent

A Bacterial Metabolite, Compound K, Induces Programmed Necrosis in MCF-7 Cells via GSK3β.

A fundamental role for interleukin-21 in the generation of T follicular helper cells

A major histocompatibility complex class I-dependent subset of memory phenotype CD8+ cells

A season for midwinter immunology

ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes

Aging leads to disturbed homeostasis of memory phenotype CD8(+) cells

An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2

Antiviral CD4+ memory T cells are IL-15 dependent

Breakdown in repression of IFN-γ mRNA leads to accumulation of self-reactive effector CD8+ T cells

CD45-mediated control of TCR tuning in naïve and memory CD8(+) T cells.

CD70-CD27 ligation between neural stem cells and CD4+ T cells induces Fas-FasL-mediated T-cell death

Calcineurin-dependent negative regulation of CD94/NKG2A expression on naive CD8+ T cells

Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}

Cytokines and T cell homeostasis

Cytokines and T-cell homeostasis

Cytokines and memory-phenotype CD8+ cells.

Cytosolic Recognition of RNA Drives the Immune Response to Heterologous Erythrocytes.

Dendritic cell internalization of α-galactosylceramide from CD8 T cells induces potent antitumor CD8 T-cell responses

Differential Responsiveness of Innate-like IL-17- and IFN-γ-Producing γδ T Cells to Homeostatic Cytokines.

Direct stimulation of T cells by membrane vesicles from antigen-presenting cells

Direct stimulation of naïve T cells by antigen-presenting cell vesicles

Direct stimulation of naïve T cells by membrane vesicles from antigen-presenting cells: Distinct roles for CD54 and B7 molecules ⬇️

Emerging cellular networks for regulation of T follicular helper cells.

Ex vivo-expanded DCs induce donor-specific central and peripheral tolerance and prolong the acceptance of donor skin grafts.

GM-CSF Culture Revisited: Preparation of Bulk Populations of Highly Pure Dendritic Cells from Mouse Bone Marrow

Generation and maintenance of memory CD4(+) T Cells

Glimpsing the real CD4+ T cell response.

Homeostasis of memory T cells

Homeostasis of naive and memory T cells

Homeostatic maintenance of T cells and natural killer cells

Homeostatic proliferation and survival of naïve and memory T cells

IL-2 Shapes the Survival and Plasticity of IL-17-Producing γδ T Cells.

IL-2/IL-2Ab complexes induce regulatory T cell expansion and protect against proteinuric CKD.

IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25

IL-21 contributes to fatal inflammatory disease in the absence of Foxp3+ T regulatory cells.

IL-7 regulates basal homeostatic proliferation of antiviral CD4+T cell memory

IL-7/anti-IL-7 mAb complexes restore T cell development and induce homeostatic T Cell expansion without lymphopenia

In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression

Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells

Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells

Interleukin 7, maestro of the immune system

Interleukin-21 is critically required in autoimmune and allogeneic responses to islet tissue in murine models. ⬇️

Is IL-7 from dendritic cells essential for the homeostasis of CD4+ T cells?

Knowing one's self: central tolerance revisited

Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus

Measurement of T and B cell turnover with bromodeoxyuridine

NF-κB2 Controls the Migratory Activity of Memory T Cells by Regulating Expression of CXCR4 in a Mouse Model of Sjögren's Syndrome

Normal T cell homeostasis: the conversion of naive cells into memory-phenotype cells

On the TRAIL of homeostatic memory T cells

Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8+ T cells

Phenotypic and Functional Changes of Peripheral Ly6C+ T Regulatory Cells Driven by Conventional Effector T Cells.

Potent antitumour activity of interleukin-2-Fc fusion proteins requires Fc-mediated depletion of regulatory T-cells

Potential use of IL-2/anti-IL-2 antibody immune complexes for the treatment of cancer and autoimmune disease

Proving negative selection in the thymus

Re-entry of mature T cells to the thymus: an epiphenomenon?

Regulation of mature T cell homeostasis

Regulation of naive T cell function by the NF-kappaB2 pathway

Regulation of naïve and memory T-cell homeostasis

Selective stimulation of T cell subsets with antibody-cytokine immune complexes.

Self/non-self discrimination and the problem of keeping T cells alive

Simultaneous deletion of MyD88 and Trif delays major histocompatibility and minor antigen mismatch allograft rejection

Spontaneous Proliferation of CD4 T Cells in RAG-Deficient Hosts Promotes Antigen-Independent but IL-2-Dependent Strong Proliferative Response of Naïve CD8 T Cells

Staying alive--naïve CD4(+) T cell homeostasis

Swapping molecules during cell-cell interactions

Systemic human T cell developmental processes in humanized mice cotransplanted with human fetal thymus/liver tissue and hematopoietic stem cells.

T cell homeostasis.

T cell memory

T cell receptor-dependent regulation of lipid rafts controls naive CD8+ T cell homeostasis

T cell-B cell collaboration.

T memory cells: quality not quantity

TCB2, a new anti-human interleukin-2 antibody, facilitates heterodimeric IL-2 receptor signaling and improves anti-tumor immunity

TCR tuning of T cell subsets.

TGF-β puts the brakes on homeostatic proliferation

The Role of Interleukin-2 in Memory CD8 Cell Differentiation ⬇️

The lymphopenic environment of CD132 (common gamma-chain)-deficient hosts elicits rapid homeostatic proliferation of naive T cells via IL-15.

The majority of murine γδ T cells at the maternal-fetal interface in pregnancy produce IL-17.

The power of dilution: using adoptive transfer to study TCR transgenic T cells

The role of interleukin-2 during homeostasis and activation of the immune system

The thymus and negative selection