List of works - Stephen Withers

A Mechanism-Based Approach to Screening Metagenomic Libraries for Discovery of Unconventional Glycosidases

scientific article published on 01 August 2018

An enzymatic pathway in the human gut microbiome that converts A to universal O type blood

scientific article published on 10 June 2019

Bioelectrocatalysis with a palladium membrane reactor

scientific article published on 31 March 2023

Chemoenzymatic Synthesis of Chito-oligosaccharides with Alternating N-d-Acetylglucosamine and d-Glucosamine

scientific article published on 19 November 2020

Discovery of UDP-Glycosyltransferases and BAHD-Acyltransferases Involved in the Biosynthesis of the Antidiabetic Plant Metabolite Montbretin A

article

Facile Formation of β-thioGlcNAc Linkages to Thiol-Containing Sugars, Peptides, and Proteins using a Mutant GH20 Hexosaminidase

scientific article published on 09 January 2019

Glycosyl Cations versus Allylic Cations in Spontaneous and Enzymatic Hydrolysis

scientific article published on 24 July 2017

High-Throughput “FP-Tag” Assay for the Identification of Glycosyltransferase Inhibitors

scientific article published on 01 February 2019

Mammalian sialyltransferases allow efficient <i>Escherichia coli</i>-based production of mucin-type O-glycoproteins but can also transfer Kdo

scientific article published in 2021

Mechanism-based covalent neuraminidase inhibitors with broad-spectrum influenza antiviral activity

scientific article

Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C-5a-Substituted Derivatives of 4-epi-Isofagomine

scientific article published on 03 September 2020

Modulating the Nucleophile of a Glycoside Hydrolase through Site-Specific Incorporation of Fluoroglutamic Acids

scientific article published on 26 June 2018

N-Alkylated Iminosugar Based Ligands: Synthesis and Inhibition of Human Lysosomal β-Glucocerebrosidase

scientific article published on 11 October 2020

Passaging of an influenza A(H1N1)pdm09 virus in a difluoro sialic acid inhibitor selects for a novel, but unfit I106M neuraminidase mutant

scientific article published on 22 June 2019

Potent GH20 N-Acetyl-β-d-hexosaminidase Inhibitors: N-Substituted 3-acetamido-4-amino-5-hydroxymethyl-cyclopentanediols

Prospecting for microbial α-N-acetylgalactosaminidases yields a new class of GH31 O-glycanase

scientific article published on 17 September 2019

Proximity Ligation-Based Fluorogenic Imaging Agents for Neuraminidases

scientific article published on 14 September 2018

Quantification of the total neuraminidase content of recent commercially-available influenza vaccines: Introducing a neuraminidase titration reagent

scientific article published on 07 December 2019

Remarkable Reactivity Differences between Glucosides with Identical Leaving Groups

scientific article

Structural Dissection of Helianthamide Reveals the Basis of Its Potent Inhibition of Human Pancreatic α-Amylase

scientific article published on 07 September 2018

Synthesis and evaluation of sensitive coumarin-based fluorogenic substrates for discovery of α-<i>N</i>-acetyl galactosaminidases through droplet-based screening

scientific article published on 07 January 2021

Synthesis of montbretin A analogues yields potent competitive inhibitors of human pancreatic α-amylase

scientific article published on 18 October 2019

Thioglycoligase derived from fungal GH3 β-xylosidase is a multi-glycoligase with broad acceptor tolerance

scientific article published on 25 September 2020

Toward universal donor blood: Enzymatic conversion of A and B to O type

scientific article published on 02 December 2019

List of works by Stephen Withers