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List of works by David Ian Stuart

"4D Biology for health and disease" workshop report

scientific article published on 15 October 2010

A RANKL mutant used as an inter-species vaccine for efficient immunotherapy of osteoporosis.

scientific article

A critical evaluation of the predicted and X-ray structures of ?-Lactalbumin

scientific article published on 01 October 1990

A functional and structural basis for TCR cross-reactivity in multiple sclerosis

scientific article

A human embryonic kidney 293T cell line mutated at the Golgi alpha-mannosidase II locus

scientific article published on 22 May 2009

A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting

scientific article

A method for the systematic comparison of the three-dimensional structures of proteins and some results

article published in 1984

A micro-patterned silicon chip as sample holder for macromolecular crystallography experiments with minimal background scattering.

scientific article

A national facility for biological cryo-electron microscopy

scientific article

A plate-based high-throughput assay for virus stability and vaccine formulation

scientific article published on 26 June 2012

A procedure for setting up high-throughput nanolitre crystallization experiments. Crystallization workflow for initial screening, automated storage, imaging and optimization

scientific article (publication date: June 2005)

A revised partiality model and post-refinement algorithm for X-ray free-electron laser data

scientific article

A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71

scientific article

A strategy for rapid and effective refinement applied to black swan lysozyme.

scientific article published in May 1995

A structural basis for immunodominant human T cell receptor recognition

scientific article

A tick protein with a modified Kunitz fold inhibits human tryptase

scientific article

A versatile ligation-independent cloning method suitable for high-throughput expression screening applications

scientific article published on 22 February 2007

Allosteric interactions of glycogen phosphorylase b. A crystallographic study of glucose 6-phosphate and inorganic phosphate binding to di-imidate-cross-linked phosphorylase b.

scientific article published on February 1984

Alpha-lactalbumin possesses a novel calcium binding loop.

scientific article

An altered position of the alpha 2 helix of MHC class I is revealed by the crystal structure of HLA-B*3501

scientific article

An idea whose time has come

scientific article

An ion-channel modulator from the saliva of the brown ear tick has a highly modified Kunitz/BPTI structure

scientific article

Analysis of antigenic surfaces of proteins

scientific article published on 01 January 1995

Antagonist HIV-1 Gag peptides induce structural changes in HLA B8

scientific article

Antibody testing for COVID-19: A report from the National COVID Scientific Advisory Panel

Antigenic Switching of Hepatitis B Virus by Alternative Dimerization of the Capsid Protein

scientific article

Application of high-throughput technologies to a structural proteomics-type analysis of Bacillus anthracis.

scientific article published on 19 September 2006

Application of in situ diffraction in high-throughput structure determination platforms.

scientific article

Application of the thermofluor PaSTRy technique for improving foot-and-mouth disease virus vaccine formulation.

scientific article published on 22 March 2016

Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens.

scientific article published on 19 September 2006

Assembly intermediates of orthoreovirus captured in the cell

scientific article published on 07 September 2020

Assembly of complex viruses exemplified by a halophilic euryarchaeal virus

scientific article published on 29 March 2019

Atomic resolution structure of Moloney murine leukemia virus matrix protein and its relationship to other retroviral matrix proteins

scientific article

Atomic snapshots of an RNA packaging motor reveal conformational changes linking ATP hydrolysis to RNA translocation

scientific article

Atomic structure of the Epstein-Barr virus portal

scientific article published on 29 August 2019

Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

scientific article published on 15 October 2020

Automated structural comparisons clarify the phylogeny of the right-hand-shaped polymerases.

scientific article published on 24 July 2014

Automatic comparison and classification of protein structures ⬇️

scientific article published on May 21, 2013

Automation of large scale transient protein expression in mammalian cells

scientific article published on 6 May 2011

Back-priming mode of 6 RNA-dependent RNA polymerase

scientific article published on 01 February 2005

Bacteriophage P23-77 Capsid Protein Structures Reveal the Archetype of an Ancient Branch from a Major Virus Lineage

scientific article

Benefits of automated crystallization plate tracking, imaging, and analysis

scientific article

Binding of (5S)-penicilloic acid to penicillin binding protein 3

scientific article

Bluetongue virus VP4 is an RNA-capping assembly line

scientific article

Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53

scientific article

Broad and strong memory CD4 + and CD8 + T cells induced by SARS-CoV-2 in UK convalescent COVID-19 patients

scientific article published on 08 June 2020

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19

scientific article published on 04 September 2020

Building meaningful models of glycoproteins

article

Building the atomic model of a boreal lake virus of unknown fold in a 3.9 Å cryo-EM map.

scientific article published on 27 October 2017

Carbohydrate and domain architecture of an immature antibody glycoform exhibiting enhanced effector functions

scientific article

Cells under siege: Viral glycoprotein interactions at the cell surface ⬇️

scientific article published on March 31, 2011

Characterization of epitope-tagged foot-and-mouth disease virus

scientific article published on 18 July 2012

Characterizing sequence variation in the VP1 capsid proteins of foot and mouth disease virus (serotype 0) with respect to virion structure

scientific article published in April 1998

Chemical and Structural Analysis of an Antibody Folding Intermediate Trapped during Glycan Biosynthesis

scientific article

Chimeric O1K foot-and-mouth disease virus with SAT2 outer capsid as an FMD vaccine candidate

scientific article published in Scientific Reports

Cloning, expression, purification, and crystallisation of HIV-2 reverse transcriptase

article

Comparison of AMP and NADH binding to glycogen phosphorylase b

scientific article published on 01 October 1983

Complementing crystallography: the role of cryo-electron microscopy in structural biology.

scientific article published on October 1999

Correction to "Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library"

scientific article published on 28 October 2019

Crystal Structure and Binding Properties of the CD2 and CD244 (2B4)-binding Protein, CD48

scientific article published in Journal of Biological Chemistry

Crystal Structure and Carbohydrate Analysis of Nipah Virus Attachment Glycoprotein: a Template for Antiviral and Vaccine Design

scientific article

Crystal Structure of Swine Vesicular Disease Virus and Implications for Host Adaptation

scientific article (publication date: May 2003)

Crystal Structure of a Novel Conformational State of the Flavivirus NS3 Protein: Implications for Polyprotein Processing and Viral Replication

scientific article

Crystal Structures of Penicillin-Binding Protein 3 from Pseudomonas aeruginosa: Comparison of Native and Antibiotic-Bound Forms

scientific article

Crystal lattice as biological phenotype for insect viruses

scientific article published on 9 September 2005

Crystal structure at 2.8 A resolution of a soluble form of the cell adhesion molecule CD2

scientific article published on November 19, 1992

Crystal structure of a 3-oxoacyl-(acylcarrier protein) reductase (BA3989) from Bacillus anthracis at 2.4-A resolution

scientific article

Crystal structure of a soluble CD28-Fab complex

scientific article

Crystal structure of cat muscle pyruvate kinase at a resolution of 2.6 A

scientific article published on October 15, 1979

Crystal structure of equine rhinitis A virus in complex with its sialic acid receptor

scientific article

Crystal structure of human α-lactalbumin at 1·7 Å resolution

scientific article published on 01 September 1991

Crystal structure of signal regulatory protein gamma (SIRPγ) in complex with an antibody Fab fragment

scientific article

Crystal structure of the CD2-binding domain of CD58 (lymphocyte function-associated antigen 3) at 1.8-A resolution

scientific article

Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues

scientific article

Crystal structure of the RNA-dependent RNA polymerase from influenza C virus

scientific article

Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2

scientific article

Crystal structure of the extracellular region of human tissue factor

scientific article

Crystal structures of penicillin-binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms

scientific article published on 23 January 2016

Crystallization and Preliminary X-ray Diffraction Characterisation of Both a Native and Selenomethionyl VLA-4 Binding Fragment of VCAM-1

scientific article published on 01 December 1994

Crystallization and preliminary X-ray analysis of CrgA, a LysR-type transcriptional regulator from pathogenic Neisseria meningitidis MC58

scientific article published on 9 August 2008

Crystallization and preliminary X-ray analysis of human rhinovirus serotype 2 (HRV2)

scientific article published on 01 August 1999

Crystallization and preliminary X-ray analysis of mouse RANK and its complex with RANKL ⬇️

scientific article published on 22 May 2009

Crystallization and preliminary X-ray crystallographic studies on the bacteriophage Φ6 RNA-dependent RNA polymerase

scientific article published on 01 November 2000

Crystallization and preliminary X-ray diffraction analysis of foot-and-mouth disease virus.

scientific article published in August 1987

Crystallization and preliminary X-ray investigation of recombinant simian immunodeficiency virus matrix protein.

scientific article published in September 1994

Crystallization and preliminary crystallographic analysis of the major capsid proteins VP16 and VP17 of bacteriophage P23-77.

scientific article

Crystallization of a calcium-binding EGF-like domain

scientific article published on 01 May 1995

Crystallization of human tumour necrosis factor

Crystallographic analysis of the binding modes of thiazoloisoindolinone non-nucleoside inhibitors to HIV-1 reverse transcriptase and comparison with modeling studies

scientific article

Crystallographic analysis of the three-dimensional structure of baboon alpha-lactalbumin at low resolution. Homology with lysozyme.

scientific article published on March 1987

Cutting complexity down to size.

scientific article published in April 1997

Design of a data model for developing laboratory information management and analysis systems for protein production

scientific article

Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1.

scientific article

Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 2.

scientific article

Determination of the affinity and kinetic constants for the interaction between the human virus echovirus 11 and its cellular receptor, CD55.

scientific article published on November 1998

Determination of the structure of a decay accelerating factor-binding clinical isolate of echovirus 11 allows mapping of mutants with altered receptor requirements for infection

scientific article

Diamond Light Source: status and perspectives

scientific article

Diffraction quality crystals of PRD1, a 66-MDa dsDNA virus with an internal membrane.

scientific article published in August 2002

Dimeric Architecture of the Hendra Virus Attachment Glycoprotein: Evidence for a Conserved Mode of Assembly

scientific article

Disruption of alpha-mannosidase processing induces non-canonical hybrid-type glycosylation

scientific article published on 20 April 2007

Domain Metastability: A Molecular Basis for Immunoglobulin Deposition?

scientific article

Double-stranded RNA virus outer shell assembly by bona fide domain-swapping

scientific article

Effects of N-butyldeoxynojirimycin and the Lec3.2.8.1 mutant phenotype on N-glycan processing in Chinese hamster ovary cells: application to glycoprotein crystallization.

scientific article published on August 1999

Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity

scientific article published on 19 November 2012

Electron Bio-Imaging Centre (eBIC): the UK national research facility for biological electron microscopy.

scientific article

Equine Rhinitis A Virus and Its Low pH Empty Particle: Clues Towards an Aphthovirus Entry Mechanism?

scientific article

Evaluation and use of in-silico structure-based epitope prediction with foot-and-mouth disease virus

scientific article

Evolution of complex RNA polymerases: the complete archaeal RNA polymerase structure

scientific article

Evolution of viral structure

scientific article

Exploiting fast detectors to enter a new dimension in room-temperature crystallography

scientific article

Expression cloning of an equine T-lymphocyte glycoprotein CD2 cDNA. Structure-based analysis of conserved sequence elements.

scientific article published on February 1994

Expression of soluble recombinant glycoproteins with predefined glycosylation: application to the crystallization of the T-cell glycoprotein CD2

scientific article published on 01 February 1993

Expression, purification and crystallization of a lyssavirus matrix (M) protein

scientific article

Expression, purification and crystallization of the ectodomain of the envelope glycoprotein E2 from Bovine viral diarrhoea virus

scientific article

Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1

scientific article

Fixed target combined with spectral mapping: approaching 100% hit rates for serial crystallography

scientific article

From SPINE to SPINE-2 complexes and beyond ⬇️

scientific article published on May 17, 2011

From lows to highs: using low-resolution models to phase X-ray data

scientific article

From lysozyme to α-lactalbumin: protein engineering and evolution

scientific article published on 01 August 1987

Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic protein ⬇️

scientific article

Functional characteristics of HIV-1 subtype C compatible with increased heterosexual transmissibility.

scientific article

Gene silencing pathway RNA-dependent RNA polymerase of Neurospora crassa: yeast expression and crystallization of selenomethionated QDE-1 protein

article

Generation and characterisation of recombinant FMDV antibodies: Applications for advancing diagnostic and laboratory assays

scientific article published in PLoS ONE

Generation and characterization of a chimeric rabbit/human Fab for co-crystallization of HIV-1 Rev.

scientific article

Genomics and structure/function studies of Rhabdoviridae proteins involved in replication and transcription.

scientific article published on 25 February 2010

Glutathione facilitates enterovirus assembly by binding at a druggable pocket

scientific article published on 03 January 2020

Glycoprotein structural genomics: solving the glycosylation problem

scientific article published on March 2007

Going soft and SAD with manganese

scientific article published on 17 December 2004

Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10

scientific article published on 07 January 2020

Hepatitis A virus and the origins of picornaviruses

scientific article

Hepatitis B small surface antigen particles are octahedral

scientific article

High resolution structures of HIV-1 RT from four RT-inhibitor complexes

scientific article

High-resolution structure of the catalytic region of MICAL (molecule interacting with CasL), a multidomain flavoenzyme-signaling molecule

scientific article

High-speed fixed-target serial virus crystallography ⬇️

scientific article

High-throughput sample handling and data collection at synchrotrons: embedding the ESRF into the high-throughput gene-to-structure pipeline.

scientific article

How baculovirus polyhedra fit square pegs into round holes to robustly package viruses

scientific article

How vaccinia virus has evolved to subvert the host immune response.

scientific article published on 17 March 2011

Humidity control as a strategy for lattice optimization applied to crystals of HLA-A*1101 complexed with variant peptides from dengue virus

scientific article

Hybrid vigor: hybrid methods in viral structure determination

scientific article

Imperfection and radiation damage in protein crystals studied with coherent radiation

scientific article published on January 2016

Implications for viral uncoating from the structure of bovine enterovirus

scientific article

Implications of the HIV-1 Rev dimer structure at 3.2 A resolution for multimeric binding to the Rev response element

scientific article

In cellulostructure determination of a novel cypovirus polyhedrin

scientific article

In situ macromolecular crystallography using microbeams

scientific article published on 17 April 2012

In vitro activities of the multifunctional RNA silencing polymerase QDE-1 of Neurospora crassa

scientific article published on 20 July 2010

Incorporation of tetanus-epitope into virus-like particles achieves vaccine responses even in older recipients in models of psoriasis, Alzheimer's and cat allergy

scientific article published on 23 October 2017

Inhibition of Apoptosis and NF-κB Activation by Vaccinia Protein N1 Occur via Distinct Binding Surfaces and Make Different Contributions to Virulence

scientific article

Insights into assembly from structural analysis of bacteriophage PRD1.

scientific article published in November 2004

Insights into the Evolution of a Complex Virus from the Crystal Structure of Vaccinia Virus D13 ⬇️

scientific article published on July 13, 2011

Insights into the pre-initiation events of bacteriophage phi 6 RNA-dependent RNA polymerase: towards the assembly of a productive binary complex.

scientific article published on 7 January 2009

Journey to the core of HIV

article

Killer cell immunoglobulin receptors and T cell receptors bind peptide-major histocompatibility complex class I with distinct thermodynamic and kinetic properties.

scientific article

Large unit cells and cellular mechanics

scientific article published on August 1, 1998

Lessons from structural genomics

scientific article (publication date: 2009)

Ligand Binding by the Immunoglobulin Superfamily Recognition Molecule CD2 Is Glycosylation-independent

scientific article published in Journal of Biological Chemistry

Localized reconstruction of subunits from electron cryomicroscopy images of macromolecular complexes

scientific article

Looking-glass land

scientific article published in Nature

Louise N. Johnson 1940–2012 ⬇️

scientific article published on December 1, 2012

Low-dose phase retrieval of biological specimens using cryo-electron ptychography

scientific article published on 02 June 2020

Lysosome sorting of β-glucocerebrosidase by LIMP-2 is targeted by the mannose 6-phosphate receptor

scientific article

Machining protein microcrystals for structure determination by electron diffraction

article published in the Proceedings of the National Academy of Sciences of the United States of America

Macromolecular assemblies: greater than their parts.

scientific article

Mapping the IkappaB kinase beta (IKKbeta)-binding interface of the B14 protein, a vaccinia virus inhibitor of IKKbeta-mediated activation of nuclear factor kappaB.

scientific article published on 7 April 2011

Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors

scientific article

Membrane structure and interactions with protein and DNA in bacteriophage PRD1.

scientific article published on November 2004

Methodology employed for the structure determination of tumour necrosis factor, a case of high non-crystallographic symmetry

scientific article published on 01 November 1991

Methods used in the structure determination of foot-and-mouth disease virus

scientific article

Model of the equine rhinitis A virus capsid: identification of a major neutralizing immunogenic site

scientific article published in September 2003

Models of the three-dimensional structures of echidna, horse, and pigeon lysozymes: Calcium-binding lysozymes and their relationship with α-lactalbumins

scientific article published on 01 August 1994

Models which explain the inhibition of reverse transcriptase by HIV-1-specific (thio)carboxanilide derivatives.

scientific article published on May 1997

More-powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules

scientific article

Near-atomic structure of Japanese encephalitis virus reveals critical determinants of virulence and stability

scientific article

Neutralization Mechanisms of Two Highly Potent Antibodies against Human Enterovirus 71.

scientific article published on 3 July 2018

Neutralization of SARS-CoV-2 by destruction of the prefusion Spike

scientific article published on 07 May 2020

Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

scientific article published on 13 July 2020

New methods for indexing multi-lattice diffraction data

scientific article

Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus  6 from De Novo Initiation to Elongation

scientific article

On the release of cppxfel for processing X-ray free-electron laser images

scientific article

Order and disorder in crystals of hexameric NTPases from dsRNA bacteriophages

scientific article published on 27 November 2003

Outrunning free radicals in room-temperature macromolecular crystallography

scientific article published on 15 June 2012

Overcoming the false-minima problem in direct methods: structure determination of the packaging enzyme P4 from bacteriophage phi13.

scientific article

Paired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47

scientific article

Perturbations in the surface structure of A22 Iraq foot-and-mouth disease virus accompanying coupled changes in host cell specificity and antigenicity

scientific article

Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses

scientific article

Phosphate-recognition sites in catalysis and control of glycogen phosphorylaseb

scientific article published on 01 October 1987

Picornavirus uncoating intermediate captured in atomic detail

scientific article

Plant-made polio type 3 stabilized VLPs-a candidate synthetic polio vaccine ⬇️

scientific article published on 15 August 2017

Plate Tectonics of Virus Shell Assembly and Reorganization in Phage Φ8, a Distant Relative of Mammalian Reoviruses

scientific article

Polyhedra structures and the evolution of the insect viruses

scientific article published on 17 August 2015

Potent antiviral agents fail to elicit genetically-stable resistance mutations in either enterovirus 71 or Coxsackievirus A16. ⬇️

scientific article

Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site

scientific article published on 10 January 2017

Preliminary Crystallographic Study of d(-)-Mandelate Dehydrogenase from Rhodotorula graminis

scientific article published on 01 October 1993

Preliminary crystallographic analysis of the major capsid protein P2 of the lipid-containing bacteriophage PM2.

scientific article published on 30 July 2005

Preliminary crystallographic data for Pneumocystis carinii dihydrofolate reductase.

scientific article published on March 1993

Production and Characterisation of Stabilised PV-3 Virus-like Particles Using

scientific article published in 2022

Production, crystallization and preliminary X-ray crystallographic studies of the bacteriophage phi 12 packaging motor

scientific article published on 25 February 2004

Production, crystallization, and preliminary X-ray analysis of the human MHC class Ib molecule HLA-E.

scientific article

Protein production and purification

scientific article

Pushing the limits of sulfur SAD phasing:de novostructure solution of the N-terminal domain of the ectodomain of HCV E1

scientific article

Rational Engineering of Recombinant Picornavirus Capsids to Produce Safe, Protective Vaccine Antigen

scientific article

Recognition surfaces of MHC class I.

scientific article published in June 1998

Reconfiguration of yeast 40S ribosomal subunit domains by the translation initiation multifactor complex.

scholarly article

Recording information on protein complexes in an information management system

scientific article

Recovery of data from perfectly twinned virus crystals revisited

scientific article

Redundant Late Domain Functions of Tandem VP2 YPXL Motifs in Nonlytic Cellular Egress of Quasi-enveloped Hepatitis A Virus

scholarly article by Olga González-López et al published 1 December 2018 in Journal of Virology

Rhabdovirus Matrix Protein Structures Reveal a Novel Mode of Self-Association

scientific article

Rigid-body Ligand Recognition Drives Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Receptor Triggering

scientific article

Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus

scientific article

SAT2 Foot-and-Mouth Disease Virus Structurally Modified for Increased Thermostability

scientific article published on 15 March 2017

Selenomethionine labeling of large biological macromolecular complexes: probing the structure of marine bacterial virus PM2.

scientific article published in November 2007

Semi-automated microseeding of nanolitre crystallization experiments

scientific article

Shared paramyxoviral glycoprotein architecture is adapted for diverse attachment strategies ⬇️

scientific article published on October 1, 2010

Signaling lymphocytic activation molecule (CDw150) is homophilic but self-associates with very low affinity.

scientific article

Some lessons from the systematic production and structural analysis of soluble (alpha)(beta) T-cell receptors

scientific article published on 26 August 2009

Some problems in relation to the structures of insulin derivatives

scientific article published on 01 August 1983

Specificity of the VP1 GH loop of Foot-and-Mouth Disease virus for alphav integrins.

scientific article published on October 2006

Statistical geometry. IV. Maximum-entropy-based extension of multiple isomorphously phased X-ray data to 4 Å resolution for α-lactalbumin

Structural Plasticity of Eph Receptor A4 Facilitates Cross-Class Ephrin Signaling

scientific article

Structural Plasticity of Eph-Receptor A4 Facilitates Cross-Class Ephrin Signaling.

scientific article published on 8 December 2009

Structural and functional analysis of protective antibodies targeting the threefold plateau of enterovirus 71

scientific article published on 16 October 2020

Structural and functional insights of RANKL-RANK interaction and signaling

scientific article

Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient

scientific article published on 31 July 2020

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL

scientific article

Structural basis for the resilience of efavirenz (DMP-266) to drug resistance mutations in HIV-1 reverse transcriptase

scientific article

Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2

scientific article

Structural basis of mechanochemical coupling in a hexameric molecular motor

scientific article

Structural changes in glycogen phosphorylase induced by phosphorylation

scientific article published in Nature

Structural comparison of two strains of foot-and-mouth disease virus subtype O1 and a laboratory antigenic variant, G67.

scientific article published in June 1995

Structural explanation for the role of Mn2+ in the activity of  6 RNA-dependent RNA polymerase

scientific article

Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E

scientific article

Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors

scientific article

Structure Elucidation of Coxsackievirus A16 in Complex with GPP3 Informs a Systematic Review of Highly Potent Capsid Binders to Enteroviruses

scientific article

Structure Unifies the Viral Universe ⬇️

scientific article published on 05 April 2012

Structure and Function of A41, a Vaccinia Virus Chemokine Binding Protein

scientific article

Structure and binding kinetics of three different human CD1d-alpha-galactosylceramide-specific T cell receptors

scientific article

Structure and functionality in flavivirus NS-proteins: perspectives for drug design

scientific article

Structure and receptor binding.

scientific article

Structure determination from a single high-pressure-frozen virus crystal

scientific article published on 19 January 2013

Structure determination of human semaphorin 4D as an example of the use of MAD in non-optimal cases

scientific article

Structure of 5-formyltetrahydrofolate cyclo-ligase fromBacillus anthracis(BA4489)

scientific article

Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data

scientific article

Structure of Cat Muscle Pyruvate Kinase at 0.26 nm Resolution

scientific article published on 01 January 1977

Structure of CrmE, a virus-encoded tumour necrosis factor receptor

scientific article

Structure of Foot-and-mouth disease virus serotype A10 61 alone and complexed with oligosaccharide receptor: receptor conservation in the face of antigenic variation

scientific article

Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors.

scientific article

Structure of Ljungan virus provides insight into genome packaging of this picornavirus.

scientific article

Structure of Signal-regulatory Protein  : A LINK TO ANTIGEN RECEPTOR EVOLUTION

scientific article

Structure of a Pestivirus Envelope Glycoprotein E2 Clarifies Its Role in Cell Entry

scientific article

Structure of a VP1-VP3 Complex Suggests How Birnaviruses Package the VP1 Polymerase

scientific article

Structure of equine infectious anemia virus matrix protein

scientific article

Structure of glycosylated NPC1 luminal domain C reveals insights into NPC2 and Ebola virus interactions

scientific article

Structure of human Aichi virus and implications for receptor binding

scientific article

Structure of pyruvate kinase and similarities with other enzymes: possible implications for protein taxonomy and evolution.

scientific article published in February 1978

Structure of the Murray Valley encephalitis virus RNA helicase at 1.9 Å resolution

scientific article

Structure of the brain-derived neurotrophic factor/neurotrophin 3 heterodimer

scientific article

Structure of the integrin binding fragment from fibrillin-1 gives new insights into microfibril organization

scientific article

Structure of the regulatory domain of the LysR family regulator NMB2055 (MetR-like protein) from Neisseria meningitidis

scientific article

Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library

article

Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design

scientific article

Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity

scientific article

Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs

scholarly article by Yuguang Zhao et al published 14 June 2018 in Journal of Medicinal Chemistry

Structures of an alanine racemase fromBacillus anthracis(BA0252) in the presence and absence of (R)-1-aminoethylphosphonic acid (L-Ala-P)

scientific article

Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation

scientific article published on 22 September 2017

Structures of orbivirus VP7: implications for the role of this protein in the viral life cycle

scientific article published on 01 July 1997

Substrate-cofactor interactions for glycogen phosphorylase b: a binding study in the crystal with heptenitol and heptulose 2-phosphate

scientific article published on 01 November 1984

Symmetrical arrangement of positively charged residues around the 5-fold axes of SAT type foot-and-mouth disease virus enhances cell culture of field viruses

scientific article published on 29 September 2020

SynchLink: an iOS app for ISPyB.

scientific article published on 4 September 2014

TakeTwo: an indexing algorithm suited to still images with known crystal parameters

scientific article

Tandem fusion of hepatitis B core antigen allows assembly of virus-like particles in bacteria and plants with enhanced capacity to accommodate foreign proteins ⬇️

scientific article published on April 2015

Target identification and mode of action of four chemically divergent drugs against Ebola virus infection

scientific article published on 22 December 2017

The B Cell Response to Foot-and-Mouth Disease Virus in Cattle following Sequential Vaccination with Multiple Serotypes

scientific article published on 22 February 2017

The C-terminal priming domain is strongly associated with the main body of bacteriophage ϕ6 RNA-dependent RNA polymerase

scientific article

The Human Low Affinity Fcγ Receptors IIa, IIb, and III Bind IgG with Fast Kinetics and Distinct Thermodynamic Properties

scientific article published in Journal of Biological Chemistry

The N-Terminus of the RNA Polymerase from Infectious Pancreatic Necrosis Virus Is the Determinant of Genome Attachment

scientific article

The Protein Information Management System (PiMS): a generic tool for any structural biology research laboratory

scientific article

The Structure of HIV-1 Rev Filaments Suggests a Bilateral Model for Rev-RRE Assembly

scientific article published on 31 May 2016

The Structure of an RNAi Polymerase Links RNA Silencing and Transcription

scientific article

The atomic structure of Carnation Mottle Virus capsid protein

scientific article

The atomic structure of the bluetongue virus core

scientific article

The crystal and molecular structure of an osmium bispyridine adduct of thymine

scientific article published on January 19, 1976

The crystal structure and biological function of leukemia inhibitory factor: implications for receptor binding

scientific article

The crystal structure of ORF-9b, a lipid binding protein from the SARS coronavirus.

scientific article published on July 2006

The crystal structure of UMP kinase from Bacillus anthracis (BA1797) reveals an allosteric nucleotide-binding site

scientific article

The crystal structure of bluetongue virus VP7

scientific article

The crystal structure of coxsackievirus A9: new insights into the uncoating mechanisms of enteroviruses

scientific article

The crystal structure of plasma gelsolin: implications for actin severing, capping, and nucleation

scientific article

The crystal structure of the catalytic domain of human urokinase-type plasminogen activator

scientific article

The democratization of cryo-EM.

scientific article published in July 2016

The highly ordered double-stranded RNA genome of bluetongue virus revealed by crystallography.

scientific article published in May 1999

The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages

scientific article published on 15 January 2015

The interaction properties of costimulatory molecules revisited

scientific article published in August 2002

The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D

scientific article

The mechanics of translocation: a molecular "spring-and-ratchet" system.

scientific article published on May 2008

The postfusion structure of baculovirus gp64 supports a unified view of viral fusion machines

scientific article

The slip-and-slide algorithm: a refinement protocol for detector geometry

scientific article published on 18 October 2017

The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex.

scientific article

The structure and function of pyruvate kinase

scientific article published on 01 June 1981

The structure and function of the outer coat protein VP9 of Banna virus

scientific article

The structure of CrgA from Neisseria meningitidis reveals a new octameric assembly state for LysR transcriptional regulators

scientific article

The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons for inhibitor design

scientific article

The structure of a cypovirus and the functional organization of dsRNA viruses.

scientific article

The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins

scientific article published on 19 February 2019

The structure of a reduced form of OxyR from Neisseria meningitidis

scientific article

The structure of foot-and-mouth disease virus: implications for its physical and biological properties.

scientific article published on June 1990

The structure of the macrophage signal regulatory protein alpha (SIRPalpha) inhibitory receptor reveals a binding face reminiscent of that used by T cell receptors

scientific article

The tandem zinc-finger region of human ZHX adopts a novel C2H2 zinc finger structure with a C-terminal extension

scientific article

The use of low-resolution phasing followed by phase extension from 7.6 to 2.5 Å resolution with noncrystallographic symmetry to solve the structure of a bacteriophage capsid protein

scientific article

The use of phase combination in crystallographic refinement: the choice of amplitude coefficients in combined syntheses

Three-dimensional structures of translating ribosomes by Cryo-EM.

scientific article published on April 2004

Tick histamine-binding proteins: isolation, cloning, and three-dimensional structure

scientific article

Toremifene interacts with and destabilizes the Ebola virus glycoprotein

scientific article published on 29 June 2016

Towards in cellulo virus crystallography

scientific article published on 28 February 2018

Towards rationalization of crystallization screening for small- to medium-sized academic laboratories: the PACT/JCSG+ strategy

scientific article published on 28 September 2005

Tracking in atomic detail the functional specializations in viral RecA helicases that occur during evolution ⬇️

scientific article

Translocation portals for the substrates and products of a viral transcription complex: the bluetongue virus core.

scientific article

Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2 ⬇️

scientific article published on 10 December 2018

Unexpected structure for the N-terminal domain of hepatitis C virus envelope glycoprotein E1

scientific article published on 16 September 2014

Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor

scientific article

Unusual Molecular Architecture of the Machupo Virus Attachment Glycoprotein

scientific article

Use of the α-mannosidase I inhibitor kifunensine allows the crystallization of apo CTLA-4 homodimer produced in long-term cultures of Chinese hamster ovary cells.

scientific article

Using Structural Information to Change the Phosphotransfer Specificity of a Two-Component Chemotaxis Signalling Complex

scientific article

Utility of recombinant integrin alpha v beta6 as a capture reagent in immunoassays for the diagnosis of foot-and-mouth disease

scientific article

Vaccinia Virus Proteins A52 and B14 Share a Bcl-2–Like Fold but Have Evolved to Inhibit NF-κB rather than Apoptosis

scientific article

Viral envelope glycoproteins swing into action.

scientific article published on July 1995

Virus crystallography.

scientific article

Virus found in a boreal lake links ssDNA and dsDNA viruses

scientific article published on 17 July 2017

Virus structure. Docking mission accomplished.

scientific article published in September 1994

Viruses

article published in 1993

What does structure tell us about virus evolution?

scientific article

Where is crystallography going?

scientific article published in February 2018

alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity

scientific journal article

xtalPiMS: a PiMS-based web application for the management and monitoring of crystallization trials

scientific article

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