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List of works by Roger Hardie

A brief history of trp: commentary and personal perspective.

scientific article published on February 2011

A histamine-activated chloride channel involved in neurotransmission at a photoreceptor synapse

scientific article published in June 1989

A quantitative estimate of the maximum amount of light-induced Ca2+ release in Drosophila photoreceptors

scientific article published in August 1996

Activation of TRP channels by protons and phosphoinositide depletion in Drosophila photoreceptors.

scientific article

Activation of heterologously expressed Drosophila TRPL channels: Ca2+ is not required and InsP3 is not sufficient.

scientific article published on September 1998

Arrestin translocation is stoichiometric to rhodopsin isomerization and accelerated by phototransduction in Drosophila photoreceptors

scientific article

Ca2+ limits the development of the light response in Drosophila photoreceptors

scientific article published in June 1993

Ca2+-Activated K+ Channels Reduce Network Excitability, Improving Adaptability and Energetics for Transmitting and Perceiving Sensory Information

scientific article published on 26 July 2019

Calcium influx via TRP channels is required to maintain PIP2 levels in Drosophila photoreceptors

scientific article published in April 2001

Calcium signalling in Drosophila photoreceptors measured with GCaMP6f.

scientific article published on 15 February 2017

Calnexin is essential for rhodopsin maturation, Ca2+ regulation, and photoreceptor cell survival

scientific article published on January 2006

Constitutive activity of the light-sensitive channels TRP and TRPL in the Drosophila diacylglycerol kinase mutant, rdgA.

scientific article published in April 2000

Depletion of PtdIns(4,5)P₂ underlies retinal degeneration in Drosophila trp mutants.

scientific article

Differential effects of ninaC proteins (p132 and p174) on light-activated currents and pupil mechanism in Drosophila photoreceptors.

scientific article published in September 1996

Distinct roles for two histamine receptors (hclA and hclB) at the Drosophila photoreceptor synapse.

scientific article

Does calcium diffusional global feedback leads to slow light adaptation in Drosophila photoreceptors? - A 3D biophysical modelling approach

scientific article

Effects of intracellular Ca2+ chelation on the light response in Drosophila photoreceptors

scientific article published on 01 December 1995

Electrophysiological Method for Whole-cell Voltage Clamp Recordings from Drosophila Photoreceptors

scientific article published on 13 June 2017

Evidence for Dynamic Network Regulation of Drosophila Photoreceptor Function from Mutants Lacking the Neurotransmitter Histamine

scientific article

Excitation of Drosophila photoreceptors by BAPTA and ionomycin: evidence for capacitative Ca2+ entry?

scientific article published in October 1996

Feedback network controls photoreceptor output at the layer of first visual synapses in Drosophila.

scientific article published on May 2006

Fly Photoreceptors Encode Phase Congruency

scientific article

Functional INAD complexes are required to mediate degeneration in photoreceptors of the Drosophila rdgA mutant

scientific article

Functional equivalence of native light-sensitive channels in the Drosophila trp301 mutant and TRPL cation channels expressed in a stably transfected Drosophila cell line

scientific article published on June 1, 1997

Genetic dissection of the phosphoinositide cycle in Drosophila photoreceptors.

scientific article

Histamine-like immunoreactivity in photoreceptors of the compound eyes and ocelli of the flies Calliphora erythrocephala and Musca domestica

scientific article published in September 1988

INDO-1 measurements of absolute resting and light-induced Ca2+ concentration in Drosophila photoreceptors

scientific article published in May 1996

In vivo analysis of the drosophila light-sensitive channels, TRP and TRPL.

scientific article published in December 1997

In vivo identification and manipulation of the Ca2+ selectivity filter in the Drosophila transient receptor potential channel.

scientific article published in January 2007

In vivo light-induced and basal phospholipase C activity in Drosophila photoreceptors measured with genetically targeted phosphatidylinositol 4,5-bisphosphate-sensitive ion channels (Kir2.1).

scientific article

In vivo tracking of phosphoinositides in Drosophila photoreceptors.

scientific article

Inhibition of phospholipase C activity in Drosophila photoreceptors by 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid (BAPTA) and di-bromo BAPTA.

scientific article published on 2 September 2005

Is histamine a neurotransmitter in insect photoreceptors?

scientific article published on 01 August 1987

Light activation, adaptation, and cell survival functions of the Na+/Ca2+ exchanger CalX.

scientific article

Light-dependent modulation of Shab channels via phosphoinositide depletion in Drosophila photoreceptors

scientific article published in August 2008

Lipids in Ca2+ signalling--an introduction.

scientific article published on 29 April 2009

Magnesium-dependent block of the light-activated and trp-dependent conductance in Drosophila photoreceptors

scientific article published in December 1995

Mechanisms of light adaptation in Drosophila photoreceptors

scientific article published in July 2005

Metarhodopsin control by arrestin, light-filtering screening pigments, and visual pigment turnover in invertebrate microvillar photoreceptors.

scientific article published on 3 November 2010

Microsaccadic sampling of moving image information provides Drosophila hyperacute vision.

scientific article

Modulation of the light response by cAMP in Drosophila photoreceptors.

scientific article published in October 1999

Molecular basis of amplification in Drosophila phototransduction: roles for G protein, phospholipase C, and diacylglycerol kinase.

scientific article published in November 2002

Multiple spectral inputs improve motion discrimination in the Drosophila visual system.

scientific article published in May 2012

Novel Ca2+ channels underlying transduction in Drosophila photoreceptors: implications for phosphoinositide-mediated Ca2+ mobilization.

scientific article

Novel potassium channels encoded by the Shaker locus in Drosophila photoreceptors

scientific article published in March 1991

Phosphoinositide-mediated phototransduction in Drosophila photoreceptors: the role of Ca2+ and trp.

scientific article published on October 1995

Photolysis of caged Ca2+ facilitates and inactivates but does not directly excite light-sensitive channels in Drosophila photoreceptors

scientific article published on January 1995

Photomechanical responses in Drosophila photoreceptors.

scientific article published in October 2012

Photosensitive TRPs

scientific article published on January 2014

Phototransduction in Drosophila

scientific article

Phototransduction in Drosophila Is Compromised by Gal4 Expression but not by InsP3 Receptor Knockdown or Mutation.

scientific article published on May 2017

Phototransduction motifs and variations

scientific article published on October 2009

Phototransduction. The invertebrate enigma

scientific article published in November 1993

Phototransduction: shedding light on translocation.

scientific article published on September 2003

Polarization Vision: Drosophila Enters the Arena

scientific article published on January 10, 2012

Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL.

scientific article published in January 1999

Professor Matti Weckström (1959-2015).

scientific article published on 9 January 2016

Projection and connectivity of sex-specific photoreceptors in the compound eye of the male housefly (Musca domestica).

scientific article published on January 1983

Protein kinase C is required for light adaptation in Drosophila photoreceptors

scientific article published in June 1993

Rapid release of Ca2+ from endoplasmic reticulum mediated by Na+/Ca2+ exchange

scientific article published on 05 March 2020

Regulation of Drosophila TRP channels by lipid messengers.

scientific article published on January 2004

Regulation of TRP channels via lipid second messengers.

scientific article

Regulation of arrestin translocation by Ca2+ and myosin III in Drosophila photoreceptors.

scientific article published in July 2012

Rescue of light responses in the Drosophila "null" phospholipase C mutant, norpAP24, by the diacylglycerol kinase mutant, rdgA, and by metabolic inhibition.

scientific article published on 5 March 2003

Robustness of neural coding in Drosophila photoreceptors in the absence of slow delayed rectifier K+ channels.

scientific article published in March 2006

Serotonin modulates the voltage dependence of delayed rectifier and Shaker potassium channels in Drosophila photoreceptors

scientific article published in April 1995

Single photon responses in Drosophila photoreceptors and their regulation by Ca2+.

scientific article published in April 2000

Speed and sensitivity of phototransduction in Drosophila depend on degree of saturation of membrane phospholipids

scientific article

Stochastic, adaptive sampling of information by microvilli in fly photoreceptors

scientific article (publication date: 7 August 2012)

TRP channels and lipids: from Drosophila to mammalian physiology.

scientific article published on 21 September 2006

TRP protein in the Drosophila photoreceptors: immunolocalization of the hypothetical light-dependent calcium channel

scientific article published in November 1999

TRP, a protein essential for inositide-mediated Ca2+ influx is localized adjacent to the calcium stores in Drosophila photoreceptors

scientific article published in May 1995

Thapsigargin and receptor-mediated activation of Drosophila TRPL channels stably expressed in a Drosophila S2 cell line.

scientific article published on April 1998

The INAD scaffold is a dynamic, redox-regulated modulator of signaling in the Drosophila eye

scientific article

The contribution of Shaker K+ channels to the information capacity of Drosophila photoreceptors

scientific article published in February 2003

The eye of the mantid shrimp

scientific article published in Nature

The target of Drosophila photoreceptor synaptic transmission is a histamine-gated chloride channel encoded by ort (hclA).

scientific article published on 23 August 2002

The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors.

scientific article

TheDrosophilaSK Channel (dSK) Contributes to Photoreceptor Performance by Mediating Sensitivity Control at the First Visual Network

scientific article published on September 28, 2011

Vision: dynamic platforms

scientific article published in November 2007

Visual transduction in Drosophila.

scientific article

Voltage-activated potassium channels in blowfly photoreceptors and their role in light adaptation

scientific article published in January 1991

Voltage-sensitive potassium channels in Drosophila photoreceptors

scientific article published in October 1991

XPORT-dependent transport of TRP and rhodopsin.

scientific article