List of works - Roger Hardie

The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors.

scientific article

Visual transduction in Drosophila.

scientific article

Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL.

scientific article published in January 1999

Phototransduction motifs and variations

scientific article published on October 2009

Novel Ca2+ channels underlying transduction in Drosophila photoreceptors: implications for phosphoinositide-mediated Ca2+ mobilization.

scientific article

In vivo analysis of the drosophila light-sensitive channels, TRP and TRPL.

scientific article published in December 1997

A histamine-activated chloride channel involved in neurotransmission at a photoreceptor synapse

scientific article published in June 1989

Is histamine a neurotransmitter in insect photoreceptors?

scientific article published on 01 August 1987

Regulation of TRP channels via lipid second messengers.

scientific article

Calcium influx via TRP channels is required to maintain PIP2 levels in Drosophila photoreceptors

scientific article published in April 2001

TRP channels and lipids: from Drosophila to mammalian physiology.

scientific article published on 21 September 2006

Constitutive activity of the light-sensitive channels TRP and TRPL in the Drosophila diacylglycerol kinase mutant, rdgA.

scientific article published in April 2000

Protein kinase C is required for light adaptation in Drosophila photoreceptors

scientific article published in June 1993

Single photon responses in Drosophila photoreceptors and their regulation by Ca2+.

scientific article published in April 2000

Molecular basis of amplification in Drosophila phototransduction: roles for G protein, phospholipase C, and diacylglycerol kinase.

scientific article published in November 2002

Phosphoinositide-mediated phototransduction in Drosophila photoreceptors: the role of Ca2+ and trp.

scientific article published on October 1995

Photomechanical Responses in Drosophila Photoreceptors

scientific article published on October 12, 2012

Activation of TRP channels by protons and phosphoinositide depletion in Drosophila photoreceptors.

scientific article

Light activation, adaptation, and cell survival functions of the Na+/Ca2+ exchanger CalX.

scientific article

The target of Drosophila photoreceptor synaptic transmission is a histamine-gated chloride channel encoded by ort (hclA).

scientific article published on 23 August 2002

Photolysis of caged Ca2+ facilitates and inactivates but does not directly excite light-sensitive channels in Drosophila photoreceptors

scientific article published on January 1995

Calnexin is essential for rhodopsin maturation, Ca2+ regulation, and photoreceptor cell survival

scientific article published on January 2006

Voltage-activated potassium channels in blowfly photoreceptors and their role in light adaptation

scientific article published in January 1991

Histamine-like immunoreactivity in photoreceptors of the compound eyes and ocelli of the flies Calliphora erythrocephala and Musca domestica

scientific article published in September 1988

INDO-1 measurements of absolute resting and light-induced Ca2+ concentration in Drosophila photoreceptors

scientific article published in May 1996

Multiple spectral inputs improve motion discrimination in the Drosophila visual system.

scientific article published in May 2012

Stochastic, adaptive sampling of information by microvilli in fly photoreceptors

scientific article (publication date: 7 August 2012)

TRP, a protein essential for inositide-mediated Ca2+ influx is localized adjacent to the calcium stores in Drosophila photoreceptors

scientific article published in May 1995

Feedback network controls photoreceptor output at the layer of first visual synapses in Drosophila.

scientific article published on May 2006

Voltage-sensitive potassium channels in Drosophila photoreceptors

scientific article published in October 1991

Mechanisms of light adaptation in Drosophila photoreceptors

scientific article published in July 2005

The contribution of Shaker K+ channels to the information capacity of Drosophila photoreceptors

scientific article published in February 2003

Phototransduction in Drosophila

scientific article

Phototransduction in Drosophila melanogaster

scientific article published on October 1, 2001

Robustness of neural coding in Drosophila photoreceptors in the absence of slow delayed rectifier K+ channels.

scientific article published in March 2006

Distinct roles for two histamine receptors (hclA and hclB) at the Drosophila photoreceptor synapse.

scientific article

Novel potassium channels encoded by the Shaker locus in Drosophila photoreceptors

scientific article published in March 1991

The INAD scaffold is a dynamic, redox-regulated modulator of signaling in the Drosophila eye

scientific article

Serotonin modulates the voltage dependence of delayed rectifier and Shaker potassium channels in Drosophila photoreceptors

scientific article published in April 1995

Modulation of the light response by cAMP in Drosophila photoreceptors.

scientific article published in October 1999

Magnesium-dependent block of the light-activated and trp-dependent conductance in Drosophila photoreceptors

scientific article published in December 1995

Functional equivalence of native light-sensitive channels in the Drosophila trp301 mutant and TRPL cation channels expressed in a stably transfected Drosophila cell line

scientific article published on June 1, 1997

In vivo identification and manipulation of the Ca2+ selectivity filter in the Drosophila transient receptor potential channel.

scientific article published in January 2007

A brief history of trp: commentary and personal perspective.

scientific article published on February 2011

Arrestin translocation is stoichiometric to rhodopsin isomerization and accelerated by phototransduction in Drosophila photoreceptors

scientific article

Activation of heterologously expressed Drosophila TRPL channels: Ca2+ is not required and InsP3 is not sufficient.

scientific article published on September 1998

XPORT-dependent transport of TRP and rhodopsin.

scientific article

In vivo light-induced and basal phospholipase C activity in Drosophila photoreceptors measured with genetically targeted phosphatidylinositol 4,5-bisphosphate-sensitive ion channels (Kir2.1).

scientific article

Ca2+ limits the development of the light response in Drosophila photoreceptors

scientific article published in June 1993

Rescue of light responses in the Drosophila "null" phospholipase C mutant, norpAP24, by the diacylglycerol kinase mutant, rdgA, and by metabolic inhibition.

scientific article published on 5 March 2003

List of works by Roger Hardie

The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors.

Visual transduction in Drosophila.

Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL.

Phototransduction motifs and variations

Novel Ca2+ channels underlying transduction in Drosophila photoreceptors: implications for phosphoinositide-mediated Ca2+ mobilization.

In vivo analysis of the drosophila light-sensitive channels, TRP and TRPL.

A histamine-activated chloride channel involved in neurotransmission at a photoreceptor synapse

Is histamine a neurotransmitter in insect photoreceptors?

Regulation of TRP channels via lipid second messengers.

Calcium influx via TRP channels is required to maintain PIP2 levels in Drosophila photoreceptors

TRP channels and lipids: from Drosophila to mammalian physiology.

Constitutive activity of the light-sensitive channels TRP and TRPL in the Drosophila diacylglycerol kinase mutant, rdgA.

Protein kinase C is required for light adaptation in Drosophila photoreceptors

Single photon responses in Drosophila photoreceptors and their regulation by Ca2+.

Molecular basis of amplification in Drosophila phototransduction: roles for G protein, phospholipase C, and diacylglycerol kinase.

Phosphoinositide-mediated phototransduction in Drosophila photoreceptors: the role of Ca2+ and trp.

Photomechanical Responses in Drosophila Photoreceptors

Activation of TRP channels by protons and phosphoinositide depletion in Drosophila photoreceptors.

Light activation, adaptation, and cell survival functions of the Na+/Ca2+ exchanger CalX.

The target of Drosophila photoreceptor synaptic transmission is a histamine-gated chloride channel encoded by ort (hclA).

Photolysis of caged Ca2+ facilitates and inactivates but does not directly excite light-sensitive channels in Drosophila photoreceptors

Calnexin is essential for rhodopsin maturation, Ca2+ regulation, and photoreceptor cell survival

Voltage-activated potassium channels in blowfly photoreceptors and their role in light adaptation

Histamine-like immunoreactivity in photoreceptors of the compound eyes and ocelli of the flies Calliphora erythrocephala and Musca domestica

INDO-1 measurements of absolute resting and light-induced Ca2+ concentration in Drosophila photoreceptors

Multiple spectral inputs improve motion discrimination in the Drosophila visual system.

Stochastic, adaptive sampling of information by microvilli in fly photoreceptors

TRP, a protein essential for inositide-mediated Ca2+ influx is localized adjacent to the calcium stores in Drosophila photoreceptors

Feedback network controls photoreceptor output at the layer of first visual synapses in Drosophila.

Voltage-sensitive potassium channels in Drosophila photoreceptors

Mechanisms of light adaptation in Drosophila photoreceptors

The contribution of Shaker K+ channels to the information capacity of Drosophila photoreceptors

Phototransduction in Drosophila

Phototransduction in Drosophila melanogaster

Robustness of neural coding in Drosophila photoreceptors in the absence of slow delayed rectifier K+ channels.

Distinct roles for two histamine receptors (hclA and hclB) at the Drosophila photoreceptor synapse.

Novel potassium channels encoded by the Shaker locus in Drosophila photoreceptors

The INAD scaffold is a dynamic, redox-regulated modulator of signaling in the Drosophila eye

Serotonin modulates the voltage dependence of delayed rectifier and Shaker potassium channels in Drosophila photoreceptors

Modulation of the light response by cAMP in Drosophila photoreceptors.

Magnesium-dependent block of the light-activated and trp-dependent conductance in Drosophila photoreceptors

Functional equivalence of native light-sensitive channels in the Drosophila trp301 mutant and TRPL cation channels expressed in a stably transfected Drosophila cell line

In vivo identification and manipulation of the Ca2+ selectivity filter in the Drosophila transient receptor potential channel.

A brief history of trp: commentary and personal perspective.

Arrestin translocation is stoichiometric to rhodopsin isomerization and accelerated by phototransduction in Drosophila photoreceptors

Activation of heterologously expressed Drosophila TRPL channels: Ca2+ is not required and InsP3 is not sufficient.

XPORT-dependent transport of TRP and rhodopsin.

In vivo light-induced and basal phospholipase C activity in Drosophila photoreceptors measured with genetically targeted phosphatidylinositol 4,5-bisphosphate-sensitive ion channels (Kir2.1).

Ca2+ limits the development of the light response in Drosophila photoreceptors

Rescue of light responses in the Drosophila "null" phospholipase C mutant, norpAP24, by the diacylglycerol kinase mutant, rdgA, and by metabolic inhibition.