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List of works by Robert Hall Michell

A Combination of Calcium Ionophore and 12-O-Tetradecanoyl-Phorbol-13-Acetate (TPA) Stimulates the Growth of Purified Resting B Cells

scientific article published on 01 November 1985

A Possible Role for Phosphatidylinositol Breakdown in Muscarinic Cholinergic Stimulus-Response Coupling ⬇️

scientific article published on January 1, 1977

A calcium-activated polyphosphoinositide phosphodiesterase in the plasma membrane of human and rabbit erythrocytes ⬇️

scientific article published on April 4, 1978

A comparison of haemoglobin-free human erythrocyte "ghosts" prepared under isoionic and hypoionic conditions [proceedings]

scientific article published on 01 January 1977

A comparison of the effects of phytohaemagglutinin and of calcium ionophore A23187 on the metabolism of glycerolipids in small lymphocytes ⬇️

scientific article published on May 15, 1977

A membrane-bound activity catalysing phosphatidylinositol breakdown to 1,2-diacylglycerol, D-myoinositol 1:2-cyclic phosphate an D-myoinositol 1-phosphate. Properties and subcellular distribution in rat cerebral cortex.

scientific article published on March 1973

A possible metabolic explanation for drug-induced phospholipidosis

scientific article published on April 1, 1976

A protein complex that regulates PtdIns(3,5)P2 levels

scientific article published in January 2009

A purified plasma membrane fraction isolated from rat liver under isotonic conditions

scientific article published on 01 September 1967

A salt-activated inositol 1,3,4,5-tetrakisphosphate 3-phosphatase at the inner surface of the human erythrocyte membrane.

scientific article

A search for a hormone-sensitive inositol lipid pool in WRK 1 mammary tumour cells

scientific article published in 1989

A simple assay for the polyphosphoinositide phosphodiesterase of the human erythrocyte membrane [proceedings]

scientific article published on 01 February 1980

A simple assay method for determination of the specific radioactivity of the gamma-phosphate group of 32P-labelled ATP.

scientific article published on March 1983

A vasopressin-like peptide in the mammalian sympathetic nervous system

scientific article published in Nature

Accumulation of 1,2-diacylglycerol in the plasma membrane may lead to echinocyte transformation of erythrocytes

scientific article published in Nature

Agonist regulation of α-adrenergic receptor numbers ⬇️

scientific article published on May 10, 1979

Altered T lymphocyte signaling in rheumatoid arthritis

scientific article published on 01 June 1995

Altered protein tyrosine phosphorylation in rheumatoid T cells which is mimicked by hydrogen peroxide

scientific article published on 01 May 1997

Analysis of the metabolic turnover of the individual phosphate groups of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate. Validation of novel analytical techniques by using 32P-labelled lipids from erythrocytes.

scientific article published on March 1984

Analytical methods to quantify phosphoinositide turnover and related reactions

Are polyphosphoinositides associated with glycophorin in human erythrocyte membranes? ⬇️

scientific article published on May 1, 1979

Basolateral plasma membranes of intestinal epithelial cells. Identification by lactoperoxidase-catalysed iodination and isolation after density perturbation with digitonin ⬇️

scientific article published on October 1, 1975

Biochemical Differentiation of the Plasma Membrane of the Intestinal Epithelial Cell

scientific article published on January 1, 1976

Bovine testis and human erythrocytes contain different subtypes of membrane-associated Ins(1,4,5)P3/Ins(1,3,4,5)P4 5-phosphomonoesterases.

scientific article

Calcium ion-dependent diacylglycerol accumulation in erythrocytes is associated with microvesiculation but not with efflux of potassium ions ⬇️

scientific article published on September 15, 1977

Calcium uptake by intracellular compartments in permeabilised enterocytes effect of inositol 1,4,5 trisphosphate

scientific article published on 01 September 1986

Cell differentiation and proliferation--simultaneous but independent?

scientific article published on December 2003

Cell proliferation and CD11b expression are controlled independently during HL60 cell differentiation initiated by 1,25 alpha-dihydroxyvitamin D(3) or all-trans-retinoic acid.

scientific article

Changes in lipid metabolism and cell morphology following attack by phospholipase C (Clostridium perfringens) on red cells or lymphocytes ⬇️

scientific article published on December 1, 1975

Changes in the levels of inositol lipids and phosphates during the differentiation of HL60 promyelocytic cells towards neutrophils or monocytes

scientific article published on 01 September 1991

Comparison of the levels of inositol metabolites in transformed haemopoietic cells and their normal counterparts.

scientific article published on February 1993

Complementation analysis in PtdInsP kinase-deficient yeast mutants demonstrates that Schizosaccharomyces pombe and murine Fab1p homologues are phosphatidylinositol 3-phosphate 5-kinases

scientific journal article

Complex changes in cellular inositol phosphate complement accompany transit through the cell cycle

scientific article published on June 2004

Dephosphorylation of 1D-myo-inositol 1,4-bisphosphate in rat liver. ⬇️

scientific article published on September 1988

Dephosphorylation of D-myo-inositol-1,4,5-trisphosphate in testes.

scientific article published in April 1991

Dephosphorylation of myo-inositol 1,4,5-trisphosphate

scientific article published in 1985

Determination of the steady-state turnover rates of the metabolically active pools of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in human erythrocytes.

scientific article published on May 1989

Diacylglycerols and phosphatidates: which molecular species are intracellular messengers?

scientific article

Differences in the Enzymic, Polypeptide, Glycopeptide, Glycolipid and Phospholipid Compositions of Plasma Membranes from the Two Surfaces of Intestinal Epithelial Cells ⬇️

scientific article published on January 1, 1975

Do inositol supplements enhance phosphatidylinositol supply and thus support endoplasmic reticulum function?

scientific article published on 03 June 2018

Drug Redeployment to Kill Leukemia and Lymphoma Cells by Disrupting SCD1-Mediated Synthesis of Monounsaturated Fatty Acids

scientific article published on 5 May 2015

Editorial overview

Editors are meant to be judges, not postmen

scientific article published in Nature

Effects of calcium-antagonistic drugs on the stimulation by carbamoylcholine and histamine of phosphatidylinositol turnover in longitudinal smooth muscle of guinea-pig ileum ⬇️

scientific article published on November 15, 1976

Elevation of Intracellular Calcium Ion Concentration Provokes Production of l,2-Diacylglycerol and Phosphatidate in Human Erythrocytes ⬇️

scientific article published on January 1, 1975

Endothelin-1 stimulates inositol phosphate production in rat testis

scientific article published on 01 November 1993

Enhanced phosphatidylinositol breakdown as a calcium-indepepdnet response of rat parotid fragments to substance P

scientific article published on 01 January 1978

Enhanced synthesis de novo of phosphatidylinositol in lymphocytes treated with cationic amphiphilic drugs ⬇️

scientific article published on June 1, 1975

Estrogenic alkylphenols induce cell death by inhibiting testis endoplasmic reticulum Ca(2+) pumps.

scientific article

Evolution of the diverse biological roles of inositols

scientific article published on January 2007

Extraction of polyphosphoinositides with neutral and acidified solvents. A comparison of guinea-pig brain and liver, and measurements of rat liver inositol compounds which are resistant to extraction.

scientific article

First came the link between phosphoinositides and Ca2+ signalling, and then a deluge of other phosphoinositide functions

scientific article published on 15 April 2009

HL60 cells halted in G1 or S phase differentiate normally

scientific article published in November 2002

Hormonal stimulation of phosphatidylinositol breakdown with particular reference to the hepatic effects of vasopressin

scientific article published on 01 October 1979

Hormone-stimulated metabolism of inositol lipids and its relationship to hepatic receptor function

scientific article published on 01 October 1981

Human erythrocyte membranes exhibit a cooperative calmodulin-dependent Ca2+-ATPase of high calcium sensitivity

scientific article published in Nature

Hypo-osmotic stress activates Plc1p-dependent phosphatidylinositol 4,5-bisphosphate hydrolysis and inositol Hexakisphosphate accumulation in yeast

scientific article published on 18 November 2003

Indomethacin potentiates the induction of HL60 differentiation to neutrophils, by retinoic acid and granulocyte colony-stimulating factor, and to monocytes, by vitamin D3.

scientific article published in April 1994

Inhibition by glucocorticoid and staurosporine of IL-4-dependent CD23 production in B lymphocytes is reversed on engaging CD40

scientific article published on 01 May 1993

Inhibition of Phosphatases and Increased Ca2+ Channel Activity by Inositol Hexakisphosphate

scientific article published on 01 October 1997

Inhibition of inositol 1,3,4-trisphosphate 5/6-kinase by amino acid modifying agents

scientific article published on 01 November 1993

Inhibition of porcine brain inositol 1,3,4-trisphosphate kinase by inositol polyphosphates, other polyol phosphates, polyanions and polycations

scientific article published on 01 August 1994

Inositol 1,2,3-trisphosphate and inositol 1,2- and/or 2,3-bisphosphate are normal constituents of mammalian cells.

scientific article published on March 1995

Inositol 1,2,3-trisphosphate is a product of InsP6 dephosphorylation in WRK-1 rat mammary epithelial cells and exhibits transient concentration changes during the cell cycle

scientific article published on 01 May 1995

Inositol 1:2(cyclic),4,5-trisphosphate is not a major product of inositol phospholipid metabolism in vasopressin-stimulated WRK1 cells.

scientific article published on May 1988

Inositol and its derivatives: Their evolution and functions ⬇️

scientific article published on November 9, 2010

Inositol derivatives: evolution and functions

scientific article

Inositol hexakisphosphate in Schizosaccharomyces pombe: synthesis from Ins(1,4,5)P3 and osmotic regulation ⬇️

scientific article published on November 1, 1998

Inositol lipid breakdown and muscarinic mechanisms

Inositol lipid breakdown as a step in α-adrenergic stimulus-response coupling

scientific article published on 01 January 1985

Inositol lipid-dependent functions in Saccharomyces cerevisiae: analysis of phosphatidylinositol phosphates

scientific article published in January 2009

Inositol lipid-mediated signalling in response to endothelin and ATP in the mammalian testis.

scientific article published on August 1995

Inositol lipid-mediated signalling in the nervous system

scientific article published on 01 January 1986

Inositol lipids and phosphates in the differentiation of blood cells

scientific article published on 01 January 1990

Inositol lipids and phosphates in the proliferation and differentiation of lymphocytes and myeloid cells

scientific article published on January 1, 1992

Inositol lipids and phosphates.

scientific article published on April 1989

Inositol lipids in cellular signalling mechanisms

scientific article published on August 1, 1992

Inositol lipids: from an archaeal origin to phosphatidylinositol 3,5-bisphosphate faults in human disease

scientific article

Inositol phosphates in receptor-mediated cell signaling: metabolic origins and interrelationships.

scientific article published on October 1990

Inositol phosphates: a remarkably versatile enzyme

scientific article

Inositol tetrakisphosphates in WRK-1 cells

scientific article published in 1988

Inositol trisphosphate and tetrakisphosphate phosphomonoesterases of rat liver

scientific article published on 01 February 1987

Interleukin 4 activates human B lymphocytes via transient inositol lipid hydrolysis and delayed cyclic adenosine monophosphate generation

scientific article published on 01 January 1990

Intracellular signaling pathways involved in the induction of apoptosis in immature thymic T lymphocytes

scientific article published on 01 June 1996

Investigation of the relationship between cell-surface calcium-ion gating and phosphatidylinositol turnover by comparison of the effects of elevated extracellular potassium ion concentration on ileium smooth muscle and pancreas ⬇️

scientific article published on November 15, 1976

Is Vasopressin-Stimulated Inositol Lipid Breakdown Intrinsic to the Mechanism of Ca2+-Mobilization at V1 Vasopressin Receptors?

scientific article published on January 1, 1983

Is phosphatidylinositol really out of the calcium gate?

scientific article published in Nature

Letter: The redirection of glyceride and phospholipid synthesis by drugs including chlorpromazine, fenfluramine, imipramine, mepyramine and local anaesthetics

scientific article published in June 1975

Levels of inositol metabolites within normal myeloid blast cells and changes during their differentiation towards monocytes

scientific article published on 01 January 1992

Localisation of bradykinin-like immunoreactivity and modulation of bradykinin-evoked phospholipase D activity by 17 beta-oestradiol in human endometrium.

scientific article

Measurement of rates of phagocytosis: the use of cellular monolayers ⬇️

scientific article published on January 1969

Membrane protein segregation during release of microvesicles from human erythrocytes ⬇️

scientific article published on June 15, 1978

Metabolic pooling of inositol lipids in mature erythrocytes and in hormone-stimulated mammalian cells

scientific article published on 01 January 1987

Metabolism of Phosphatidate at the Plasma Membrane ⬇️

scientific article published on January 1, 1977

MgATP2- and the molecular organization of erythrocyte membranes [proceedings]

scientific article published on 01 January 1978

Modulation of the organization of erythrocyte membrane phospholipids by cytoplasmic ATP. The susceptibility of isoionic human erythrocytes ghosts to attack by detergents and phospholipase C

scientific article published on 01 May 1978

Molecular events following activation of muscarinic receptors: the role of inositol phospholipids

scientific article published on January 1, 1982

Monocytically Differentiating HL60 Cells Proliferate Rapidly before They Mature

scientific article published on 01 December 1999

Morton Medal Lecture. New insights into the roles of phosphoinositides and inositol polyphosphates in yeast.

scientific article

Multiple metabolic pools of phosphoinositides and phosphatidate in human erythrocytes incubated in a medium that permits rapid transmembrane exchange of phosphate

scientific article published on May 1987

Muscarinic cholinergic stimulation of phosphatidylinositol turnover in isolated rat superior cervical sympathetic ganglia ⬇️

scientific article published on March 1, 1976

Muscarinic cholinergic stimulation of phosphatidylinositol turnover in the longitudinal smooth muscle of guinea-pig ileum ⬇️

scientific article published on March 15, 1976

Nuclear PIPs

Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis ⬇️

scientific article published on November 13, 1997

PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection

PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection

article

Permeability characteristics of erythrocyte ghosts prepared under isoionic conditions by a glycol-induced osmotic lysis

scientific article published on March 17, 1977

Phosphatidylinositol 3,5-bisphosphate and Fab1p/PIKfyve underPPIn endo-lysosome function

scientific article

Phosphatidylinositol 3,5-bisphosphate: metabolism and cellular functions

scientific article

Phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate: lipids in search of a function

scientific journal article

Phosphatidylinositol cleavage catalysed by the soluble fraction from lymphocytes. Activity at pH5.5 and pH7.0

scientific article

Phosphatidylinositol kinase activity in Saccharomyces cerevisiae.

scientific article published on April 1972

Phosphatidylinositol metabolism in rat hepatocytes stimulated by glycogenolytic hormones. Effects of angiotensin, vasopressin, adrenaline, ionophore A23187 and calcium-ion deprivation ⬇️

scientific article published on September 15, 1979

Phosphatidylinositol metabolism in rat hepatocytes stimulated by vasopressin.

scientific article published on January 1981

Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance

scientific article

Polyphosphoinositide breakdown as the initiating reaction in receptor-stimulated inositol phospholipid metabolism.

scientific article published in May 1983

Polyphosphoinositides in Isolated Preparations of Human Erythrocyte Membrane Glycophorin

scientific article published on April 1, 1979

Preparation of erythrocyte ghosts by a glycol-induced osmotic lysis under isoionic conditions

scientific article published on 01 April 1976

Production of 1,2-diacylglycerol in human erythrocyte 'ghosts' exposed to very low calcium ion concentrations

scientific article published on 01 January 1976

Production of 1,2-diacylglycerol in human erythrocyte membranes exposed to low concentrations of calcium ions

scientific article published on 01 December 1976

PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49

scientific article

Q & A: Bob Michell

scientific article published in August 2003

Rapid accumulation of inositol phosphates in isolated rat superior cervical sympathetic ganglia exposed to V1-vasopressin and muscarinic cholinergic stimuli.

scientific article published on August 1984

Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones.

scientific article published on June 1983

Rapid transbilayer diffusion of 1,2-diacylglycerol and its relevance to control of membrane curvature

scientific article published in Nature

Receptor occupancy dose--response curve suggests that phosphatidyl-inositol breakdown may be intrinsic to the mechanism of the muscarinic cholinergic receptor

scientific article published on 01 October 1976

Recovery of membrane micro-vesicles from human erythrocytes stored for transfusion: a mechanism for the erythrocyte discocyte-to-spherocyte shape transformation

scientific article published on 01 January 1977

Redistribution of protein kinase C during mitogenesis of human B lymphocytes

scientific article published on 01 February 1986

Release of diacylglycerol-enriched vesicles from erythrocytes with increased intracellular [Ca2+]

scientific article published in Nature

Second messengers. Sphingolipid signalling.

scientific article published on April 1994

Second-messenger pathways involved in the regulation of survival in germinal-centre B cells and in Burkitt lymphoma lines

scientific article published on 01 December 1992

Selective release of plasma-membrane enzymes from rat hepatocytes by a phosphatidylinositol-specific phospholipase C.

scientific article published on April 1980

Significance of minor glycerolipids in membrane structure and function

scientific article published on January 1, 1976

Similar effects of substance P and related peptides on salivation and on phosphatidylinositol turnover in rat salivary glands

scientific article published on 01 July 1980

Simultaneous oscillations of cytoplasmic free Ca2+ concentration and Ins(1,4,5)P3 concentration in mouse pancreatic beta-cells

scientific article published on January 1994

Stepwise enzymatic dephosphorylation of inositol 1,4,5-trisphosphate to inositol in liver ⬇️

scientific article published on November 22, 1984

Stimulated inositol lipid metabolism: An introduction ⬇️

scientific article published on October 1, 1982

Stimulation of phosphatidylinositol turnover by histamine, 5-hydroxytryptamine and adrenaline in the longitudinal smooth muscle of guinea pig ileum ⬇️

scientific article published on June 15, 1976

Stimulation of the breakdown and resynthesis of of phosphatidylinositol in rat hepatocytes by angiotensin, vasopressin and adrenaline

scientific article published on 01 January 1978

Stimulation of tyrosine phosphorylation without inositol lipid hydrolysis in human B lymphocytes on engaging CD72.

scientific article published on March 1993

Stimulus-Response Coupling at α-Adrenergic Receptors ⬇️

scientific article published on January 1, 1978

Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors

scientific article

Synthesis and iron binding studies of myo-inositol 1,2,3-trisphosphate and (±)-myo-inositol 1,2-bisphosphate, and iron binding studies of all myo-inositol tetrakisphosphates

scientific article published in February 1996

The Possible Involvement of Phosphatidylinositol Breakdown in the Mechanism of Stimulus-Response Coupling at Receptors which Control Cell-Surface Calcium Gates ⬇️

scientific article published on January 1, 1977

The Role of Phosphatidylinositol 4,5 Bisphosphate Breakdown in Cell-Surface Receptor Activation

scientific article published on 01 January 1984

The control by Ca2+ of the polyphosphoinositide phosphodiesterase and the Ca2+-pump ATPase in human erythrocytes.

scientific article published on January 1982

The inositol 1,4,5-trisphosphate 6-kinase of Schizosaccharomyces pombe

scientific article published on 01 February 1997

The inositol phosphates in WRK1 rat mammary tumour cells ⬇️

scientific article published on September 1, 1992

The inositol trisphosphate phosphomonoesterase of the human erythrocyte membrane ⬇️

scientific article published on April 1, 1982

The interrelationships of the inositol phosphates formed in vasopressin-stimulated WRK-1 rat mammary tumour cells ⬇️

scientific article published on September 1, 1992

The intracellular distribution of inositol polyphosphates in HL60 promyeloid cells.

scientific article published on October 1994

The involvement of inositol lipids and phosphates in signalling in the fission yeast Schizosaccharomyces pombe

scientific article published on 01 May 1995

The multiplying roles of inositol lipids and phosphates in cell control processes

scientific article published on January 1, 1997

The opening of the inositol 1,4,5-trisphosphate-sensitive Ca2+ channel in rat cerebellum is inhibited by caffeine ⬇️

scientific article published on March 1, 1992

The polyphosphoinositide phosphodiesterase of erythrocyte membranes ⬇️

scientific article published on July 15, 1981

The possible role of lipids in control of membrane fusion during secretion

scientific article published on 01 January 1979

The relationship between Ca2+-mediated polyphosphoinositide phosphodiesterase activity, 1, 2-diacylglycerol accumulation, and microvesiculation in erythrocytes

scientific article published on January 1, 1979

The relationship between calcium ion gates and the stimulation of phosphatidylinositol turnover

scientific article published on January 1, 1977

The relationship of calcium to receptor-controlled stimulation of phosphatidylinositol turnover. Effects of acetylcholine, adrenaline, calcium ions, cinchocaine and a bivalent cation ionophore on rat parotid-gland fragments ⬇️

scientific article (publication date: June 1975)

The role of inositol lipid hydrolysis in the selection of immature thymocytes ⬇️

scientific article published on April 1, 1991

The sequential determination model of hematopoiesis

scientific article published on 7 September 2007

The site of diphosphoinositide synthesis in rat liver

scientific article published on 01 November 1965

The use of phospholipase C to detect structural changes in the membranes of human erythrocytes aged by storage ⬇️

scientific article published on September 22, 1978

The versatility of haematopoietic stem cells: implications for leukaemia

scientific article published on August 2010

Transfer of very low density lipoprotein from hen plasma into egg yolk

scientific article published on 01 March 1974

Vac14 controls PtdIns(3,5)P(2) synthesis and Fab1-dependent protein trafficking to the multivesicular body

scientific article

Variant cell lines from the human promyelocyte line HL60.

scientific article published on January 1982

Versatility and nuances of the architecture of haematopoiesis - Implications for the nature of leukaemia

scientific article

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