List of works by Jesper Qualmann Svejstrup

A RECQ5-RNA polymerase II association identified by targeted proteomic analysis of human chromatin

scholarly article

A Rad26-Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damage

scientific article

A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin

scientific article published on 13 June 2019

A role for checkpoint kinase-dependent Rad26 phosphorylation in transcription-coupled DNA repair in Saccharomyces cerevisiae.

scientific article published on 9 November 2009

A role for noncoding transcription in activation of the yeast PHO5 gene

scholarly article

A ubiquitin-binding domain in Cockayne syndrome B required for transcription-coupled nucleotide excision repair

scientific article published on June 2010

A ubiquitylation site in Cockayne syndrome B required for repair of oxidative DNA damage, but not for transcription-coupled nucleotide excision repair

scientific article published on 07 April 2016

An Assay for Studying Ubiquitylation of RNA Polymerase II and Other Proteins in Crude Yeast Extracts

scientific article published on 01 January 2006

An iron-sulfur cluster domain in Elp3 important for the structural integrity of elongator.

scientific article published on 5 November 2008

An rtt109-independent role for vps75 in transcription-associated nucleosome dynamics

scientific article

Analysis of RNA polymerase II ubiquitylation and proteasomal degradation

scientific article published on 13 February 2019

Annotation matters: validating the discovery of cancer drivers

scientific article published on 31 August 2020

CDK13 cooperates with CDK12 to control global RNA polymerase II processivity

scientific article published on 29 April 2020

Camptothecin inhibits both the cleavage and religation reactions of eukaryotic DNA topoisomerase I

scientific article published on 01 December 1992

Causes and consequences of RNA polymerase II stalling during transcript elongation

scientific article published on 18 November 2020

Characterization of an altered DNA catalysis of a camptothecin-resistant eukaryotic topoisomerase I.

scientific article

Chromatin elongation factors

scientific article

Cockayne syndrome B protein regulates recruitment of the Elongin A ubiquitin ligase to sites of DNA damage.

scientific article published on 14 March 2017

Communication between Distant Sites in RNA Polymerase II through Ubiquitylation Factors and the Polymerase CTD

article by Baggavalli P. Somesh et al published April 2007 in Cell

Contending with transcriptional arrest during RNAPII transcript elongation

scientific article published on 8 March 2007

Correction: Retention of the Native Epigenome in Purified Mammalian Chromatin

scientific article published on 16 October 2015

DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation

scientific article

DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator

scientific article

DNA damage-induced Def1-RNA polymerase II interaction and Def1 requirement for polymerase ubiquitylation in vitro

scientific article published on 27 May 2004

Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligase Nedd4, but not Cockayne syndrome proteins or BRCA1

scientific article

Different forms of TFIIH for transcription and DNA repair: holo-TFIIH and a nucleotide excision repairosome

scientific article

Direct inhibition of RNA polymerase II transcription by RECQL5.

scientific article published on July 2009

Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation

scientific article

Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair

scientific article published on December 1993

Dysregulation of gene expression as a cause of Cockayne syndrome neurological disease

scientific article

Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability

scientific article published on 10 September 2019

Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability

scientific article published on 09 June 2021

Elongator complex: how many roles does it play?

scientific article published on 26 April 2007

Elongator interactions with nascent mRNA revealed by RNA immunoprecipitation

scientific article published in May 2004

Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo

scientific article

Elongator, a Multisubunit Component of a Novel RNA Polymerase II Holoenzyme for Transcriptional Elongation

scientific article published on 01 January 1999

Evidence for a mediator cycle at the initiation of transcription.

scientific article

Evidence for distinct mechanisms facilitating transcript elongation through chromatin in vivo

scientific article published on 30 September 2004

Evidence that transcript cleavage is essential for RNA polymerase II transcription and cell viability

scientific article published on April 2010

GTP-dependent binding and nuclear transport of RNA polymerase II by Npa3 protein

scientific article

Genome-wide reconstitution of chromatin transactions reveals that RSC preferentially disrupts H2AZ-containing nucleosomes

scientific article published on 16 May 2019

Heat shock induces premature transcript termination and reconfigures the human transcriptome

scientific article published on 02 February 2022

Hereditary dysautonomias: current knowledge and collaborations for the future.

scientific article

Hyperphosphorylation of the C-terminal repeat domain of RNA polymerase II facilitates dissociation of its complex with mediator

scientific article

In vitro reconstitution of PHO5 promoter chromatin remodeling points to a role for activator-nucleosome competition in vivo

scientific article

Incision of a 1,3-intrastrand d(GpTpG)-cisplatin adduct by nucleotide excision repair proteins from yeast

scientific article

Increasing the rate of chromatin remodeling and gene activation--a novel role for the histone acetyltransferase Gcn5

scientific article

Interacting partners of the Tfb2 subunit from yeast TFIIH.

scientific article

Interaction of Fcp1 phosphatase with elongating RNA polymerase II holoenzyme, enzymatic mechanism of action, and genetic interaction with elongator

scientific article published on 24 November 2004

Involvement of yeast carboxy-terminal domain kinase I (CTDK-I) in transcription elongation in vivo

scientific article published in April 2001

Isolation and mass spectrometry of transcription factor complexes

scientific article

Keeping RNA and DNA Apart during Transcription ⬇️

scientific article published on September 1, 2003

Mechanisms of transcription-coupled DNA repair

scientific article

Mechanistic interpretation of promoter-proximal peaks and RNAPII density maps.

scientific article

Minimal DNA duplex requirements for topoisomerase I-mediated cleavage in vitro

scientific article published in Journal of Biological Chemistry

Minimal DNA requirement for topoisomerase II-mediated cleavage in vitro

scientific article published in August 1990

Molecular architecture, structure-function relationship, and importance of the Elp3 subunit for the RNA binding of holo-elongator

scientific article

MultiDsk: a ubiquitin-specific affinity resin

scientific article

Multiomic Analysis of the UV-Induced DNA Damage Response ⬇️

scientific article

Multiple mechanisms confining RNA polymerase II ubiquitylation to polymerases undergoing transcriptional arrest

scientific article published in June 2005

Mutation of cancer driver MLL2 results in transcription stress and genome instability.

scientific article published on February 2016

New technique for uncoupling the cleavage and religation reactions of eukaryotic topoisomerase I. The mode of action of camptothecin at a specific recognition site

scientific article

Nucleotide excision repair in the yeast Saccharomyces cerevisiae: its relationship to specialized mitotic recombination and RNA polymerase II basal transcription

scientific article published on January 1995

Overlapping roles for the histone acetyltransferase activities of SAGA and elongator in vivo

scientific article

Pharmacological Bypass of Cockayne Syndrome B Function in Neuronal Differentiation

scientific article published on 09 March 2016

Physical and functional interaction between Elongator and the chromatin-associated Kti12 protein

scientific article

Proteasome-mediated processing of Def1, a critical step in the cellular response to transcription stress

scientific article published on August 2013

Purification and characterization of human topoisomerase I mutants

scientific article

Purification and characterization of the human elongator complex

scientific article

Purification of Elongating RNA Polymerase II and Other Factors from Yeast Chromatin

scientific article published on 01 January 2003

RECQL5 controls transcript elongation and suppresses genome instability associated with transcription stress

scientific article

RECQL5 helicase: connections to DNA recombination and RNA polymerase II transcription

scientific article published on 18 January 2010

RNA Immunoprecipitation to Determine RNA-Protein Associations In Vivo

scientific article published on 01 June 2009

RNA immunoprecipitation for determining RNA-protein associations in vivo

scientific article published on August 2006

RNA polymerase II Transcript Elongation

scholarly article by Jesper Qualmann Svejstrup published in January 2013

RNA polymerase II collision interrupts convergent transcription

scientific article

RNA polymerase II: a "nobel" enzyme demystified

scientific article published in December 2006

RNA polymerase transcription factor IIH holoenzyme from yeast.

scientific article

Recent insights on DNA repair. The mechanism of damaged nucleotide excision in eukaryotes and its relationship to other cellular processes

scientific article published on July 1994

Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK

scientific article (publication date: 16 December 1994)

Reprogramming chromatin

scientific article published on 03 July 2012

Rescue of arrested RNA polymerase II complexes

scientific article

Retention of the Native Epigenome in Purified Mammalian Chromatin

scientific article

Reversal of RNA polymerase II ubiquitylation by the ubiquitin protease Ubp3.

scientific article

Role of elongator subunit Elp3 in Drosophila melanogaster larval development and immunity.

scientific article

SCAF4 and SCAF8, mRNA Anti-Terminator Proteins

scientific article published on 16 May 2019

Spreading of Sir3 protein in cells with severe histone H3 hypoacetylation

scientific article

Stability, flexibility, and dynamic interactions of colliding RNA polymerase II elongation complexes

scientific article published on July 2009

Studies of the topoisomerase II-mediated cleavage and religation reactions by use of a suicidal double-stranded DNA substrate ⬇️

scientific article published in Journal of Biological Chemistry

Studying RNA–Protein Interactions In Vivo By RNA Immunoprecipitation

Subunits of yeast RNA polymerase II transcription factor TFIIH encoded by the CCL1 gene.

scientific article published in January 1996

Synovial sarcoma mechanisms: a series of unfortunate events.

scientific article published in March 2013

The Cellular Response to Transcription-Blocking DNA Damage.

scientific article published in May 2018

The DNA binding, cleavage, and religation reactions of eukaryotic topoisomerases I and II.

scientific article published on January 1994

The Elp2 Subunit of Elongator and Elongating RNA Polymerase II Holoenzyme Is a WD40 Repeat Protein

scientific article published in Journal of Biological Chemistry

The NC2 alpha and beta subunits play different roles in vivo

scientific article published on December 2002

The RAD7, RAD16, and RAD23 genes of Saccharomyces cerevisiae: requirement for transcription-independent nucleotide excision repair in vitro and interactions between the gene products

scientific article published on February 1997

The RNA polymerase II transcription cycle: cycling through chromatin

scientific article published on March 2004

The interface between transcription and mechanisms maintaining genome integrity

scientific article published on March 2010

The yeast TFB1 and SSL1 genes, which encode subunits of transcription factor IIH, are required for nucleotide excision repair and RNA polymerase II transcription

scientific article

Transcript Elongation by RNA Polymerase II.

scientific article published on January 2010

Transcription Repair Coupling Factor

scientific article published on 01 June 2002

Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast

scientific article published in Nature

Transcription impairment and cell migration defects in elongator-depleted cells: implication for familial dysautonomia

scientific article published on May 2006

Transcription. Histones face the FACT.

scientific article

Transcription: another mark in the tail

scientific article published on 22 May 2012

Transcriptional inhibition of genes with severe histone h3 hypoacetylation in the coding region

scientific article published on October 2002

Translation stress and collided ribosomes are co-activators of cGAS

scientific article published in July 2021

Triptolide is an inhibitor of RNA polymerase I and II-dependent transcription leading predominantly to down-regulation of short-lived mRNA.

scientific article published on 06 October 2009

UV Irradiation Induces a Non-coding RNA that Functionally Opposes the Protein Encoded by the Same Gene

scientific article published on 16 February 2017

Ubiquitylation and degradation of elongating RNA polymerase II: the last resort

scientific article published on 31 August 2012

Using TTchem-seq for profiling nascent transcription and measuring transcript elongation

scientific article published on 08 January 2020

Vps75, a new yeast member of the NAP histone chaperone family

scientific article

Yeast nucleotide excision repair proteins Rad2 and Rad4 interact with RNA polymerase II basal transcription factor b (TFIIH)

scientific article published on June 1994

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