List of works - James Scott

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

scientific article

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

scientific article published on 24 March 2017

A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies

scientific article

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

Adaptive expression of microRNA-125a in adipose tissue in response to obesity in mice and men.

scientific article

An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22

scientific article

An integrated reverse functional genomic and metabolic approach to understanding orotic acid-induced fatty liver

scientific article published on 13 April 2004

Bio-informatics analysis of a gene co-expression module in adipose tissue containing the diet-responsive gene Nnat

scientific article

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

CDKN2B expression in adipose tissue of familial combined hyperlipidemia patients

scientific article published on 08 October 2013

Common genetic variation near MC4R is associated with waist circumference and insulin resistance

scientific article

Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians

scientific article published on 03 August 2009

Confirmed Locus on Chromosome 11p and Candidate Loci on 6q and 8p for the Triglyceride and Cholesterol Traits of Combined Hyperlipidemia ⬇️

scientific article published on September 18, 2003

Coronary heart disease in Indian Asians

scientific article

Corrigendum to "Lipoprotein apheresis efficacy, challenges and outcomes: A descriptive analysis from the UK Lipoprotein Apheresis Registry, 1989-2017" [Atherosclerosis 290 (November 2019) 44-51]

scientific article published on 11 January 2020

Dietary cholesterol directly induces acute inflammasome-dependent intestinal inflammation

scientific article

Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models

scientific article published on 15 April 2007

Do Cardiometabolic Risk Factors Influence Amyloid, Tau, and Neuronal Function in APOE4 Carriers and Non-Carriers in Alzheimer's Disease Trajectory?

scientific article published on 01 January 2018

Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study

scientific article

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

scientific article published on 21 December 2016

Erratum to: A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies.

scientific article published on 21 April 2016

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 23 January 2018

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease

scientific article

Genetic loci influencing kidney function and chronic kidney disease

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genetic variation in SCN10A influences cardiac conduction

scientific article

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

scientific journal article

Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels ⬇️

scientific article published on 22 September 2016

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

scientific article published on 16 October 2011

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

scientific article

Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels

scientific article

Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

scientific article

Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene

scientific article

Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides

scientific article

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Glycomics investigation into insulin action

scientific article published on 10 January 2006

Improved cardiovascular outcomes following temporal advances in lipid-lowering therapy in a genetically-characterised cohort of familial hypercholesterolaemia homozygotes.

scientific article

Integrated genomic approaches identify major pathways and upstream regulators in late onset Alzheimer's disease

scientific article published on 23 July 2015

Integrated mass spectrometric strategy for characterizing the glycans from glycosphingolipids and glycoproteins: direct identification of sialyl Le(x) in mice

scientific article

Investigation of Genetic Variation Underlying Central Obesity amongst South Asians

scientific article

Linkage and association between distinct variants of the APOA1/C3/A4/A5 gene cluster and familial combined hyperlipidemia

scientific article published on 09 October 2003

Lipoprotein apheresis efficacy, challenges and outcomes: A descriptive analysis from the UK Lipoprotein Apheresis Registry, 1989-2017

scientific article published on 12 September 2019

Lipoproteins, inflammation, and atherosclerosis

scientific article published on 01 April 2003

Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice

scholarly article

Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance

scientific article

Microbiome inhibition of IRAK-4 by trimethylamine mediates metabolic and immune benefits in high-fat-diet-induced insulin resistance

Mild stroke symptoms as the initial presentation of a patient with underlying subacute bacterial endocarditis

scientific article published on 16 December 2011

Molecular basis of the Cd36 chromosomal deletion underlying SHR defects in insulin action and fatty acid metabolism.

scientific article

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

article

Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders

scientific article

Neuronatin deletion causes postnatal growth restriction and adult obesity in 129S2/Sv mice

scientific article published on 15 September 2018

Neuronatin regulates pancreatic β cell insulin content and secretion

New gene functions in megakaryopoiesis and platelet formation

scientific article published on 30 November 2011

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

scientific article published on 18 June 2018

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Nutrigenomics of high fat diet induced obesity in mice suggests relationships between susceptibility to fatty liver disease and the proteasome

scientific article

Pathophysiology and biochemistry of cardiovascular disease

scientific article published on June 2004

Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice

scientific article

Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes

scientific article

Radiation hybrid mapping of 70 rat genes from a data set of differentially expressed genes

scientific article

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 19 December 2017

Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

Systematic Analysis and Biomarker Study for Alzheimer's Disease

scientific article published in Scientific Reports

The Differential Influence of Immune, Endocytotic, and Lipid Metabolism Genes on Amyloid Deposition and Neurodegeneration in Subjects at Risk of Alzheimer's Disease

scientific article published on 17 November 2020

The South Asian genome.

scientific article

The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay

scientific article

The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)

The influence of pharmacogenetics on fatty liver disease in the wistar and kyoto rats: a combined transcriptomic and metabonomic study

scientific journal article

The liver X receptor and atherosclerosis

scientific article published in November 2007

The transcriptional corepressor RIP140 regulates oxidative metabolism in skeletal muscle

scientific article

The use of a highly informative CA repeat polymorphism within the abetalipoproteinaemia locus (4q22–24)

scientific article published in December 1997

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

scientific article

Untargeted Metabolome Quantitative Trait Locus Mapping Associates Variation in Urine Glycerate to Mutant Glycerate Kinase

article

List of works by James Scott

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

Adaptive expression of microRNA-125a in adipose tissue in response to obesity in mice and men.

An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22

An integrated reverse functional genomic and metabolic approach to understanding orotic acid-induced fatty liver

Bio-informatics analysis of a gene co-expression module in adipose tissue containing the diet-responsive gene Nnat

Biological, clinical and population relevance of 95 loci for blood lipids

CDKN2B expression in adipose tissue of familial combined hyperlipidemia patients

Common genetic variation near MC4R is associated with waist circumference and insulin resistance

Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians

Confirmed Locus on Chromosome 11p and Candidate Loci on 6q and 8p for the Triglyceride and Cholesterol Traits of Combined Hyperlipidemia ⬇️

Coronary heart disease in Indian Asians

Corrigendum to "Lipoprotein apheresis efficacy, challenges and outcomes: A descriptive analysis from the UK Lipoprotein Apheresis Registry, 1989-2017" [Atherosclerosis 290 (November 2019) 44-51]

Dietary cholesterol directly induces acute inflammasome-dependent intestinal inflammation

Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models

Do Cardiometabolic Risk Factors Influence Amyloid, Tau, and Neuronal Function in APOE4 Carriers and Non-Carriers in Alzheimer's Disease Trajectory?

Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

Erratum to: A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies.

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease

Genetic loci influencing kidney function and chronic kidney disease

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Genetic variation in SCN10A influences cardiac conduction

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels ⬇️

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels

Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene

Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Glycomics investigation into insulin action

Improved cardiovascular outcomes following temporal advances in lipid-lowering therapy in a genetically-characterised cohort of familial hypercholesterolaemia homozygotes.

Integrated genomic approaches identify major pathways and upstream regulators in late onset Alzheimer's disease

Integrated mass spectrometric strategy for characterizing the glycans from glycosphingolipids and glycoproteins: direct identification of sialyl Le(x) in mice

Investigation of Genetic Variation Underlying Central Obesity amongst South Asians

Linkage and association between distinct variants of the APOA1/C3/A4/A5 gene cluster and familial combined hyperlipidemia

Lipoprotein apheresis efficacy, challenges and outcomes: A descriptive analysis from the UK Lipoprotein Apheresis Registry, 1989-2017

Lipoproteins, inflammation, and atherosclerosis

Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice

Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance

Microbiome inhibition of IRAK-4 by trimethylamine mediates metabolic and immune benefits in high-fat-diet-induced insulin resistance

Mild stroke symptoms as the initial presentation of a patient with underlying subacute bacterial endocarditis

Molecular basis of the Cd36 chromosomal deletion underlying SHR defects in insulin action and fatty acid metabolism.

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders

Neuronatin deletion causes postnatal growth restriction and adult obesity in 129S2/Sv mice

Neuronatin regulates pancreatic β cell insulin content and secretion

New gene functions in megakaryopoiesis and platelet formation

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

Nutrigenomics of high fat diet induced obesity in mice suggests relationships between susceptibility to fatty liver disease and the proteasome

Pathophysiology and biochemistry of cardiovascular disease

Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice

Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes

Radiation hybrid mapping of 70 rat genes from a data set of differentially expressed genes

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Seventy-five genetic loci influencing the human red blood cell

Systematic Analysis and Biomarker Study for Alzheimer's Disease

The Differential Influence of Immune, Endocytotic, and Lipid Metabolism Genes on Amyloid Deposition and Neurodegeneration in Subjects at Risk of Alzheimer's Disease

The South Asian genome.

The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay

The genetic architecture of type 2 diabetes

The influence of pharmacogenetics on fatty liver disease in the wistar and kyoto rats: a combined transcriptomic and metabonomic study

The liver X receptor and atherosclerosis

The transcriptional corepressor RIP140 regulates oxidative metabolism in skeletal muscle

The use of a highly informative CA repeat polymorphism within the abetalipoproteinaemia locus (4q22–24)

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

Untargeted Metabolome Quantitative Trait Locus Mapping Associates Variation in Urine Glycerate to Mutant Glycerate Kinase