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Authors whose works are in public domain in at least one jurisdiction

List of works by Andrew Paul McMahon

(Re)Building a Kidney.

scientific article published on 17 January 2017

A Simple Bioreactor-Based Method to Generate Kidney Organoids from Pluripotent Stem Cells

scientific article published on 19 July 2018

A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney

scientific article

A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord

scientific journal article

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract

scientific article

A high-resolution anatomical ontology of the developing murine genitourinary tract.

scientific article

A novel distal convoluted tubule-specific Cre-recombinase driven by the NaCl cotransporter gene

scientific article published on 13 July 2020

A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway

scientific article published on October 2006

A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning.

scientific article

AP-1 family members act with Sox9 to promote chondrocyte hypertrophy.

scientific article published on 28 July 2016

Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma

scientific article published on August 2008

Acute biomarkers of traumatic brain injury: relationship between plasma levels of ubiquitin C-terminal hydrolase-L1 and glial fibrillary acidic protein

scientific article published on 09 October 2013

An ES cell system for rapid, spatial and temporal analysis of gene function in vitro and in vivo

scientific article

An ancient yet flexible cis-regulatory architecture allows localized Hedgehog tuning by patched/Ptch1.

scientific article published on 05 May 2016

An embryonic stem cell‐based system for rapid analysis of transcriptional enhancers ⬇️

scientific article published on January 17, 2012

An immunohistochemical identification key for cell types in adult mouse prostatic and urethral tissue sections

scientific article published on 16 November 2017

Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment

scientific article published on 6 June 2009

Apoptosis induced by vitamin A signaling is crucial for connecting the ureters to the bladder

scientific article published on 25 September 2005

Atlas of Gene Expression in the Developing Kidney at Microanatomic Resolution

article

Atlas of gene expression in the developing kidney at microanatomic resolution

scientific article

Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs

scientific article published on 18 June 2014

Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state

scientific article

Boc and Gas1 each form distinct Shh receptor complexes with Ptch1 and are required for Shh-mediated cell proliferation

scientific article published on June 2011

Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation

scientific journal article

Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature

scientific journal article

Cellular Recruitment by Podocyte-Derived Pro-migratory Factors in Assembly of the Human Renal Filter

scientific article published on 26 September 2019

Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.

scientific article published on 13 July 2017

Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis.

scientific article published on 27 August 2013

Collecting duct-derived cells display mesenchymal stem cell properties and retain selective in vitro and in vivo epithelial capacity

scientific article

Conserved and Divergent Features of Human and Mouse Kidney Organogenesis.

scientific article published on 15 February 2018

Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney

scientific article published on 15 February 2018

Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning

scientific article published on 15 February 2018

Corrigendum to “A high-resolution anatomical ontology of the developing murine genitourinary tract” [Gene Expression Patterns 7 (2007) 680–699]

article

Dach1, a vertebrate homologue of Drosophila dachshund, is expressed in the developing eye and ear of both chick and mouse and is regulated independently of Pax and Eya genes

scientific article

Defining kidney biology to understand renal disease

scientific article published on 26 December 2013

Derivation of Embryonic Stem-Cell Lines from Human Blastocysts

scientific article (publication date: 25 March 2004)

Development of the Human Fetal Kidney from Mid to Late Gestation in Male and Female Infants.

scientific article published on 20 December 2017

Developmental biology. Grasping limb patterning

scientific article published in July 2008

Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney

scientific article

Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators

scientific article published on February 2016

Disparate levels of beta-catenin activity determine nephron progenitor cell fate.

scientific article published on 26 April 2018

Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate

scientific journal article

Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development

scientific journal article

Dose dependency of Disp1 and genetic interaction between Disp1 and other hedgehog signaling components in the mouse

scientific journal article

Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain ⬇️

scientific article published on December 1, 2002

Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain

scientific article published in November 2002

Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning ⬇️

scientific article published on August 1, 2013

Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities

scientific article

Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis

scientific article

Fate-mapping of the epithelial seam during palatal fusion rules out epithelial-mesenchymal transformation

scientific article published in September 2005

Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb

scientific article published in April 2009

Filopodia: The Cellular Quills of Hedgehog Signaling? ⬇️

scientific article published on May 28, 2013

GFAP-BDP as an acute diagnostic marker in traumatic brain injury: results from the prospective transforming research and clinical knowledge in traumatic brain injury study.

scientific article published on August 2013

GUDMAP: the genitourinary developmental molecular anatomy project

scientific article published on 20 February 2008

Gene Regulatory Networks Mediating Canonical Wnt Signal-Directed Control of Pluripotency and Differentiation in Embryo Stem Cells ⬇️

scientific article published on December 1, 2013

Generation of kidney ureteric bud and collecting duct organoids that recapitulate kidney branching morphogenesis

scientific article published on 28 April 2020

Genetic manipulation of ureteric bud tip progenitors in the mammalian kidney through an Adamts18 enhancer driven tet-on inducible system

scientific article published on 14 November 2019

Genome-wide RNA Tomography in the zebrafish embryo

scientific article published in October 2014

Global quantification of tissue dynamics in the developing mouse kidney

scientific article

Hedgehog is required for murine yolk sac angiogenesis.

scientific article

Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis

scientific article

Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract

scientific article

Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia

scientific journal article

Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis

scientific article

Hedgehog signaling is essential for endothelial tube formation during vasculogenesis

scientific journal article

Hedgehog-Gli Pathway Activation during Kidney Fibrosis ⬇️

scientific article published on February 17, 2012

Hedgehog-driven myogenic tumors recapitulate skeletal muscle cellular heterogeneity

scientific article published on 9 October 2015

High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population

scientific article published on 08 July 2009

Identification of a multipotent self-renewing stromal progenitor population during mammalian kidney organogenesis

scientific article

Identification of molecular compartments and genetic circuitry in the developing mammalian kidney ⬇️

scientific article

Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton

scientific journal article

Image-based modeling of kidney branching morphogenesis reveals GDNF-RET based Turing-type mechanism and pattern-modulating WNT11 feedback

scientific article published on 16 January 2019

Independent regulation of skeletal growth by Ihh and IGF signaling

scientific article published on 30 June 2006

Indian hedgehog signaling from endothelial cells is required for sclera and retinal pigment epithelium development in the mouse eye

scientific journal article

Induction and patterning of the metanephric nephron

scientific article

Intrinsic epithelial cells repair the kidney after injury

scientific article

Invasion of distal nephron precursors associates with tubular interconnection during nephrogenesis.

scientific article

In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes

scientific article published on 01 July 2019

Loss of Emx2 function leads to ectopic expression of Wnt1 in the developing telencephalon and cortical dysplasia.

scientific article published in May 2003

Macrophage Wnt7b is critical for kidney repair and regeneration

scientific journal article

Mammalian kidney development: principles, progress, and projections ⬇️

scientific article published in May 2012

Maternal inheritance of Cre activity in a Sox2Cre deleter strain ⬇️

scientific article published on October 1, 2003

Measurement of the glial fibrillary acidic protein and its breakdown products GFAP-BDP biomarker for the detection of traumatic brain injury compared to computed tomography and magnetic resonance imaging.

scientific article

Modeling recent human evolution in mice by expression of a selected EDAR variant

scientific article

Modeling the spatio-temporal network that drives patterning in the vertebrate central nervous system

scientific article published on April 2009

Molecular characterization of the transition from acute to chronic kidney injury following ischemia/reperfusion

scientific article published on 21 September 2017

Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease

scientific article published on 23 June 2019

Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand

scientific article

Mouse brain organization revealed through direct genome-scale TF expression analysis

scientific article published on 01 December 2004

Mutational analysis of genes with ureteric progenitor cell-specific expression in branching morphogenesis of the mouse kidney

scientific article published on 04 February 2020

Mutations in Hedgehog pathway genes in fetal rhabdomyomas ⬇️

scientific article published on September 1, 2013

Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning

scientific article

Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways

scientific journal article

Noggin antagonism of BMP4 signaling controls development of the axial skeleton in the mouse

scientific article published in October 2005

Noncanonical Wnt signaling through G protein-linked PKCdelta activation promotes bone formation

scientific article published on January 2007

Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning

scientific article

Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function

scientific article

Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis

scientific article published on 01 June 2018

Recent genetic studies of mouse kidney development

scientific article published in October 2004

Regulation of skeletogenic differentiation in cranial dermal bone

scientific article published in August 2007

Renoprotective and Immunomodulatory Effects of GDF15 following AKI Invoked by Ischemia-Reperfusion Injury

scientific article published on 07 February 2020

Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development

scientific article published on May 2017

Retinoid signaling in progenitors controls specification and regeneration of the urothelium

scientific article

Retraction: Dose dependency of Disp1 and genetic interaction between Disp1 and other hedgehog signaling components in the mouse

scientific article published on 01 December 2005

SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult

scientific article

Shh signaling within the dental epithelium is necessary for cell proliferation, growth and polarization

scientific journal article

Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney

scientific article published on 01 November 2019

Single-Cell RNA Sequencing of the Adult Mouse Kidney: From Molecular Cataloging of Cell Types to Disease-Associated Predictions

scientific article published on 18 September 2018

Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks

scientific journal article

Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development

scientific journal article

Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney

scientific article

Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum

scientific journal article

Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal

scientific journal article

Sox9 Activation Highlights a Cellular Pathway of Renal Repair in the Acutely Injured Mammalian Kidney

scientific article published on 12 August 2015

Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction

scientific journal article

Symptomatology and functional outcome in mild traumatic brain injury: results from the prospective TRACK-TBI study.

scientific article published on 31 October 2013

Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions.

scientific article published on 16 April 2018

Temporal differences in granulosa cell specification in the ovary reflect distinct follicle fates in mice

scientific article published on 14 February 2012

The GUDMAP database--an online resource for genitourinary research

scientific article

The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development

scientific journal article

The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis.

scientific article published on 9 April 2012

The cdx genes and retinoic acid control the positioning and segmentation of the zebrafish pronephros

scientific article

The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice

scientific journal article

The limb bud Shh-Fgf feedback loop is terminated by expansion of former ZPA cells

scientific article

The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance

scientific journal article

Transcriptional profiling of Wnt4 mutant mouse kidneys identifies genes expressed during nephron formation

scientific journal article

Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies.

scientific article

Transient expression of the bHLH factor neurogenin-2 marks a subpopulation of neural crest cells biased for a sensory but not a neuronal fate

scientific article

Translational profiles of medullary myofibroblasts during kidney fibrosis.

scientific article

WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature

scientific journal article

Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development

scientific journal article

Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development.

scientific article published on July 2003

Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment

scientific article published on 05 December 2018

Wnt3 signaling in the epiblast is required for proper orientation of the anteroposterior axis

scientific journal article

Wnt4/β−Catenin Signaling in Medullary Kidney Myofibroblasts ⬇️

scientific article published on June 13, 2013

Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme

scientific article

Wnt9b is the mutated gene involved in multifactorial nonsyndromic cleft lip with or without cleft palate in A/WySn mice, as confirmed by a genetic complementation test

scientific journal article

Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system

scientific journal article

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