Search filters

List of works by Andrew James McMichael

A Comprehensive Analysis of Key Immune Checkpoint Receptors on Tumor-Infiltrating T Cells From Multiple Types of Cancer

scientific article published on 25 October 2019

A DNA/MVA-based candidate human immunodeficiency virus vaccine for Kenya induces multi-specific T cell responses in rhesus macaques ⬇️

scientific article published on January 1, 2002

A Plea for Justice for Jailed Medical Workers

scientific article published in Science

A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A.

scientific article published on 30 January 2013

A human immunodeficiency virus 1 (HIV-1) clade A vaccine in clinical trials: stimulation of HIV-specific T-cell responses by DNA and recombinant modified vaccinia virus Ankara (MVA) vaccines in humans

scientific article published in April 2004

A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells

scientific article

A re-evaluation of the frequency of CD8+ T cells specific for EBV in healthy virus carriers.

scientific article

A review of vaccines for HIV prevention.

scientific article published in January 2003

A strongly selected mutation in the HIV-1 genome is independent of T cell responses and neutralizing antibodies.

scientific article published on 10 October 2017

A structural basis for immunodominant human T cell receptor recognition

scientific article

AIDS/HIV. Finding footprints among the trees

scientific article published in March 2007

APOBEC3G-induced hypermutation of human immunodeficiency virus type-1 is typically a discrete "all or nothing" phenomenon

scientific article

Abnormalities in iNKT cells are associated with impaired ability of monocytes to produce IL-10 and suppress T-cell proliferation in sarcoidosis

scientific article published on 12 May 2014

Activation of Invariant NKT Cells in Early Phase of Experimental Autoimmune Encephalomyelitis Results in Differentiation of Ly6Chi Inflammatory Monocyte to M2 Macrophages and Improved Outcome ⬇️

scientific article published on 08 June 2012

Activation of invariant NKT cells enhances the innate immune response and improves the disease course in influenza A virus infection

scientific article published in July 2008

Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication

article

Acute HIV-1 Infection ⬇️

scientific article published on May 19, 2011

Alcohol, tobacco and breast cancer--collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease

scientific article published in November 2002

Allergen-specific CD8(+) T cells and atopic disease

scientific article

Altered primary CD8+ T cell response to a modified virus Ankara(MVA)-vectored vaccine in the absence of CD4+ T cell help

scientific article

Alternative Spliced CD1D Transcripts in Human Bronchial Epithelial Cells ⬇️

scientific article published on August 11, 2011

An early HIV mutation within an HLA-B*57-restricted T cell epitope abrogates binding to the killer inhibitory receptor 3DL1.

scientific article published on 23 March 2011

Annulling a dangerous liaison: vaccination strategies against AIDS and tuberculosis

scientific article (publication date: April 2005)

Another HIV vaccine failure: where to next?

scientific article published on December 2013

Anti-viral cytotoxic T cells inhibit the growth of cancer cells with antibody targeted HLA class I/peptide complexes in SCID mice

scientific article published on 01 April 2002

Antibody-targeted MHC complex-directed expansion of HIV-1- and KSHV-specific CD8+ lymphocytes: a new approach to therapeutic vaccination

article

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

scientific article

Antisense-Derived HIV-1 Cryptic Epitopes Are Not Major Drivers of Viral Evolution during the Acute Phase of Infection

article

Antiviral Inhibitory Capacity of CD8+ T cells Predicts the Rate of CD4+ T-Cell Decline in HIV-1 Infection ⬇️

scientific article published on June 18, 2012

Aromatic residues at the edge of the antibody combining site facilitate viral glycoprotein recognition through membrane interactions

scientific article

Author Correction: Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding

scientific article published in Nature Communications

Avian influenza A(H5N1) viruses can directly infect and replicate in human gut tissues

scientific article published in April 2010

Background morbidity in HIV vaccine trial participants from various geographic regions as assessed by unsolicited adverse events

scientific article

Biodistribution and persistence of an MVA-vectored candidate HIV vaccine in SIV-infected rhesus macaques and SCID mice

scientific article published in February 2005

Blocking development of a CD8+ T cell response by targeting lymphatic recruitment of APC.

scientific article published in February 2009

Boosted Influenza-Specific T Cell Responses after H5N1 Pandemic Live Attenuated Influenza Virus Vaccination.

scientific article

Brigitte Alice Askonas. 1 April 1923—9 January 2013

Broad TCR usage in functional HIV-1-specific CD8+ T cell expansions driven by vaccination during highly active antiretroviral therapy

scientific article published on 01 July 2007

Broad and strong memory CD4 + and CD8 + T cells induced by SARS-CoV-2 in UK convalescent COVID-19 patients

scientific article published on 08 June 2020

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19

scientific article published on 04 September 2020

Broadly targeted CD8⁺ T cell responses restricted by major histocompatibility complex E.

scientific article published on 21 January 2016

Bystander T cell activation--implications for HIV infection and other diseases

scientific article published on 25 September 2006

CCL3L1 and HIV/AIDS susceptibility

scientific article published on October 2009

CD4+ T Follicular Helper Cells in Human Tonsils and Blood Are Clonally Convergent but Divergent from Non-Tfh CD4+ Cells

scientific article published on 01 January 2020

CD56bright NK cells are enriched at inflammatory sites and can engage with monocytes in a reciprocal program of activation

scientific article published on 01 November 2004

CD56bright human NK cells differentiate into CD56dim cells: role of contact with peripheral fibroblasts

scientific article

CTLs target Th cells that acquire bystander MHC class I-peptide complex from APCs

scientific article

Capturing the antigen landscape: HLA-E, CD1 and MR1

scientific article published on 21 August 2019

Casting a wider net: Immunosurveillance by nonclassical MHC molecules ⬇️

scientific article published on 21 February 2019

Cell-surface expression and immune receptor recognition of HLA-B27 homodimers

scientific article published on 01 November 2002

Changes in Frequency of HIV‐1–Specific Cytotoxic T Cell Precursors and Circulating Effectors after Combination Antiretroviral Therapy in Children

scientific article published in August 1999

Characterization of CD4(+) CTLs ex vivo

scientific article published on 01 June 2002

Characterization of the CD4+ T cell response to Epstein-Barr virus during primary and persistent infection

scientific article published on September 2003

Circulating and Tissue-Resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function Is Altered During Inflammation

scientific article published on 3 August 2017

Clinical experience with plasmid DNA- and modified vaccinia virus Ankara-vectored human immunodeficiency virus type 1 clade A vaccine focusing on T-cell induction

scientific article published on January 2007

Clonal selection, clonal senescence, and clonal succession: the evolution of the T cell response to infection with a persistent virus

scientific article published in April 2002

Cohort Profile: The Flu Watch Study.

scientific article

Combined single-clade candidate HIV-1 vaccines induce T cell responses limited by multiple forms of in vivo immune interference

scientific article published in February 2007

Comment on clinical development of candidate HIV vaccines: different problems for different vaccines

scientific article published on April 2014

Common genetic variation and the control of HIV-1 in humans

scientific article published in December 2009

Common human genetic variants and HIV-1 susceptibility: a genome-wide survey in a homogeneous African population

scientific article

Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study.

scientific article

Comparing pooled peptides with intact protein for accessing cross-presentation pathways for protective CD8+ and CD4+ T cells

scientific article published on 04 February 2009

Comparison of Sexual Behavior and HIV Risk between Two HIV-1 Serodiscordant Couple Cohorts: The CHAVI 002 Study ⬇️

scientific article published on May 22, 2012

Comparison of neutralizing antibody responses elicited from highly diverse polyvalent heterotrimeric HIV-1 gp140 cocktail immunogens versus a monovalent counterpart in rhesus macaques

scientific article

Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope

scientific article

Conserved footprints of APOBEC3G on Hypermutated human immunodeficiency virus type 1 and human endogenous retrovirus HERV-K(HML2) sequences

scientific article published on 18 June 2008

Contribution of proteasome-catalyzed peptide cis-splicing to viral targeting by CD8+ T cells in HIV-1 infection

scientific article published on 20 November 2019

Copy number variation of KIR genes influences HIV-1 control

scientific article

Correction. The presence of prolines in the flanking region of an immunodominant HIV-2 gag epitope influences the quality and quantity of the epitope generated.

scientific article

Correction: Copy Number Variation of KIR Genes Influences HIV-1 Control.

scientific article published on 16 December 2011

Correction: Design and Pre-Clinical Evaluation of a Universal HIV-1 Vaccine.

scientific article

Corrigendum to 'Unusual antigen presentation offers new insight into HIV vaccine design' [Curr Opin Immunol 46 (2017) 75-81]

article

Cross-reactive cytotoxic T lymphocytes against a HIV-1 p24 epitope in slow progressors with B*57.

scientific article published in May 2002

Crystal structures and KIR3DL1 recognition of three immunodominant viral peptides complexed to HLA-B*2705.

scientific article published in February 2005

DNA vaccines against human immunodeficiency virus type 1.

scientific article

Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infection

scientific article

Design and pre-clinical evaluation of a universal HIV-1 vaccine

scientific article published in 2007

Design and tests of an HIV vaccine

scientific article

Design and validation of an enzyme-linked immunospot assay for use in clinical trials of candidate HIV vaccines

scientific article published on 01 June 2002

Detailed and atypical HLA-E peptide binding motifs revealed by a novel peptide exchange binding assay

scientific article published on 27 July 2020

Detection of broad functional gag-specific CD4+ T cell responses in HIV-1-infected subjects following therapeutic immunization with rMVA expressing an HIV-1 gag immunogen.

scientific article published on 21 December 2006

Development of a DNA-MVA/HIVA vaccine for Kenya

scientific article

Differences in HIV-specific T cell responses between HIV-exposed and -unexposed HIV-seronegative individuals

scientific article

Direct Visualization of Antigen-specific CD8+T Cells during the Primary Immune Response to Epstein-Barr Virus In Vivo ⬇️

scientific article published on May 4, 1998

Direct relationship between virus load and systemic immune activation in HIV-2 infection

scientific article

Distinct kinetics of Gag-specific CD4+ and CD8+ T cell responses during acute HIV-1 infection

scientific article published on 27 January 2012

Dynamics of T cell responses in HIV infection

scientific article published on 01 April 2002

Dysfunctional Epstein-Barr virus (EBV)-specific CD8(+) T lymphocytes and increased EBV load in HIV-1 infected individuals progressing to AIDS-related non-Hodgkin lymphoma

scientific article published in July 2001

Early acquisition of cytolytic function and transcriptional changes in a primary CD8+ T-cell response in vivo.

scientific article

Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection

scientific article

Efficient priming of antigen-specific cytotoxic T lymphocytes by human cord blood dendritic cells

scientific article published on October 2003

Elevation of intact and proteolytic fragments of acute phase proteins constitutes the earliest systemic antiviral response in HIV-1 infection

scientific article

Emergence of a distinct HIV-specific IL-10-producing CD8+ T-cell subset with immunomodulatory functions during chronic HIV-1 infection.

scientific article published on 29 August 2013

Enriched HLA-E and CD94/NKG2A Interaction Limits Antitumor CD8+ Tumor-Infiltrating T Lymphocyte Responses

scientific article published on 18 June 2019

Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication

scientific article

Evolution of the immune system in humans from infancy to old age

scientific article

Ex vivo phenotype and frequency of influenza virus-specific CD4 memory T cells

scientific article

Examination of influenza specific T cell responses after influenza virus challenge in individuals vaccinated with MVA-NP+M1 vaccine

scientific article

Expansion and diversification of virus-specific T cells following immunization of human immunodeficiency virus type 1 (HIV-1)-infected individuals with a recombinant modified vaccinia virus Ankara/HIV-1 Gag vaccine.

scientific article

Expression of leukocyte immunoglobulin-like receptors and natural killer receptors on virus-specific CD8+ T cells during the evolution of Epstein-Barr virus-specific immune responses in vivo

scientific article

Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China

scientific article published on 11 May 2011

Fitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infection

scientific article

Fully functional HLA B27-restricted CD4+ as well as CD8+ T cell responses in TCR transgenic mice

scientific article published on 01 January 2004

Functional Differences Exist between TNFα Promoters Encoding the Common −237G SNP and the Rarer HLA-B*5701-Linked A Variant ⬇️

scientific article published on July 13, 2012

Functional characteristics of HIV-1 subtype C compatible with increased heterosexual transmissibility.

scientific article

Gene set analysis of lung samples provides insight into pathogenesis of progressive, fibrotic pulmonary sarcoidosis.

scientific article published on March 2010

Generation and characterisation of CD1d tetramer produced by a lentiviral expression system

scientific article published on 26 November 2007

Generation of tumour-rejecting anti-carbohydrate monoclonal antibodies using melanoma modified with Fas ligand.

scientific article

Gonococcal cervicitis is associated with reduced systemic CD8+ T cell responses in human immunodeficiency virus type 1-infected and exposed, uninfected sex workers

scientific article published on 30 April 2002

HIV T cell vaccines, the importance of clades

scientific article

HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC

scientific article

HIV vaccines

scientific article published on 01 January 2006

HIV vaccines 1983-2003.

scientific article

HIV-1 Conserved Mosaics Delivered by Regimens with Integration-Deficient DC-Targeting Lentiviral Vector Induce Robust T Cells

scientific article published on February 2017

HIV-1 Env-specific cytotoxic T-lymphocyte responses in exposed, uninfected Kenyan sex workers: a prospective analysis

scientific article published in October 2004

HIV-1 Vaccines: Let’s Get Physical ⬇️

scientific article published on March 21, 2013

HIV-1 down-regulates the expression of CD1d via Nef.

scientific article published on February 2006

HIV-2 gene product-specific T cell responses and viraemia control.

scientific article published on 21 December 2006

HIV-Host Interactions: Implications for Vaccine Design

scientific article

HIV-specific cytotoxic T cells from long-term survivors select a unique T cell receptor

scientific article

HIV/AIDS. HLA leaves its footprints on HIV

scientific article published on 01 May 2002

HIV‐1: From escapism to conservatism ⬇️

scientific article published on 01 December 2011

HLA allele distributions and associations in a cohort of LTNPs from China

scientific article published on 6 June 2011

HLA correlates in a cohort of slow progressors from China: effects on HIV-1 disease progression

scientific article published in November 2013

HLA-B may be more protective against HIV-1 than HLA-A because it resists negative regulatory factor (Nef) mediated down-regulation

scientific article

HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors.

scientific article published on August 2004

High Frequency of Cytomegalovirus‐Specific Cytotoxic T‐Effector Cells in HLA‐A*0201–Positive Subjects during Multiple Viral Coinfections

article

High Level Antibody Response to Pandemic Influenza H1N1/09 Virus Is Associated With Interferon-Induced Transmembrane Protein-3 rs12252-CC in Young Adults.

scientific article

High Pro-Inflammatory Cytokine Secretion and Loss of High Avidity Cross-Reactive Cytotoxic T-Cells during the Course of Secondary Dengue Virus Infection

scientific article

High clade C HIV-1 viremia: how did we get here and where are we going?

scientific article published on 01 July 2011

High levels of virus-specific CD4+ T cells predict severe pandemic influenza A virus infection.

scientific article

Highly avid, oligoclonal, early-differentiated antigen-specific CD8+ T cells in chronic HIV-2 infection

article

Human CD4+ T cells are predominantly distributed among six phenotypically and functionally distinct subsets

scientific article published on 01 November 2005

Human CD4+ memory T cells are preferential targets for bystander activation and apoptosis.

scientific article

Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo

scientific article

Identification of H5N1-specific T-cell responses in a high-risk cohort in vietnam indicates the existence of potential asymptomatic infections

scientific article published on 11 November 2011

Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses

scientific article

Identification of novel HIV-1-derived HLA-E-binding peptides

article

Identification of self-lipids presented by CD1c and CD1d proteins

scientific article

Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection

scientific article

Immune escape through T cell antagonism?

Immune perturbations in HIV-1-infected individuals who make broadly neutralizing antibodies

scientific article

Immunisation with recombinant modified vaccinia virus Ankara expressing HIV-1 gag in HIV-1-infected subjects stimulates broad functional CD4+ T cell responses

scientific article published in October 2006

Immunology. Antigen processing takes a new direction

scientific article published in May 2013

Immunotherapy with antibody-targeted HLA class I complexes: results of in vivo tumour cell killing and therapeutic vaccination

scientific article published on 20 August 2007

Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome

scientific article

Impaired IFN-gamma-secreting capacity in mycobacterial antigen-specific CD4 T cells during chronic HIV-1 infection despite long-term HAART.

scientific article

Importance of a conserved TCR J α-encoded tyrosine for T cell recognition of an HLA B27/ peptide complex

scientific article published on 01 September 1998

Improved detection of latent Mycobacterium tuberculosis infection in HIV‐1 seropositive individuals using cultured cellular assays ⬇️

scientific article published on December 1, 2010

In pursuit of an HIV vaccine: an interview with Andrew McMichael ⬇️

scientific article published on May 21, 2013

Increased detection of proliferating, polyfunctional, HIV-1-specific T cells in DNA-modified vaccinia virus Ankara-vaccinated human volunteers by cultured IFN-gamma ELISPOT assay

scientific article published on April 2009

Increased frequencies of CD4+ CD25(high) regulatory T cells in acute dengue infection

scientific article (publication date: 14 May 2007)

Increased sequence diversity coverage improves detection of HIV-specific T cell responses

scientific article published in November 2007

Induction of human immunodeficiency virus type 1-specific T cells by a bluetongue virus tubule-vectored vaccine prime-recombinant modified virus Ankara boost regimen

scientific article

Induction of long-lasting multi-specific CD8+ T cells by a four-component DNA-MVA/HIVA-RENTA candidate HIV-1 vaccine in rhesus macaques

scientific article published in October 2006

Induction of multifunctional human immunodeficiency virus type 1 (HIV-1)-specific T cells capable of proliferation in healthy subjects by using a prime-boost regimen of DNA- and modified vaccinia virus Ankara-vectored vaccines expressing HIV-1 Gag c

scientific article published on May 2006

Influenza vaccines: mTOR inhibition surprisingly leads to protection

scientific article published in December 2013

Initial HIV-1 antigen-specific CD8+ T cells in acute HIV-1 infection inhibit transmitted/founder virus replication

scientific article

Innate immune responses in acute HIV-1 infection: protective or pathogenic?

article

Interaction of HLA-B27 homodimers with KIR3DL1 and KIR3DL2, unlike HLA-B27 heterotrimers, is independent of the sequence of bound peptide

scientific article published on 01 May 2007

Interferon-induced transmembrane protein-3 genetic variant rs12252-C is associated with severe influenza in Chinese individuals

scientific article

Interferon-induced transmembrane protein-3 rs12252-C is associated with rapid progression of acute HIV-1 infection in Chinese MSM cohort

scientific article published on May 2015

Interleukin-10 responses to therapeutic vaccination during highly active antiretroviral therapy and after analytical therapy interruption.

scientific article published in October 2009

Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity

scientific article published on 27 July 2020

Involvement of the 4-1BB/4-1BBL pathway in control of monocyte numbers by invariant NKT cells

scientific article published on 17 March 2014

Is a Human CD8 T-Cell Vaccine Possible, and if So, What Would It Take? Could a CD8+ T-Cell Vaccine Prevent Persistent HIV Infection?

scientific article published on 18 December 2017

Ita Askonas and her influence in the field of antigen presentation

scientific article published on 7 December 2013

Lack of Epstein-Barr virus- and HIV-specific CD27- CD8+ T cells is associated with progression to viral disease in HIV-infection

scientific article published in October 2002

Lack of Truncated IFITM3 Transcripts in Cells Homozygous for the rs12252-C Variant That is Associated With Severe Influenza Infection

scientific article published on 30 November 2017

Large clonal expansions of CD8+ T cells in acute infectious mononucleosis

scientific article published on August 1996

Legacy of the influenza pandemic 1918: The host T cell response

scientific article published on 01 August 2018

Lessons learned from HIV-1 vaccine trials: new priorities and directions

scientific article published on 18 April 2012

Long peptides induce polyfunctional T cells against conserved regions of HIV-1 with superior breadth to single-gene vaccines in macaques.

scientific article

Longitudinal COVID-19 profiling associates IL-1Ra and IL-10 with disease severity and RANTES with mild disease

scientific article published on 05 June 2020

Loss of DNAM-1 contributes to CD8+ T-cell exhaustion in chronic HIV-1 infection

scientific article

Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling.

scientific article published on March 2003

M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza

scientific article published on 06 April 2017

Magnitude of alloresponses to MHC class I/II expressing human cardiac myocytes is limited by their intrinsic ability to process and present antigenic peptides.

scientific article published on June 2003

Maintenance of HIV-specific CD4+ T cell help distinguishes HIV-2 from HIV-1 infection.

scientific article published in June 2006

Mature CD8(+) T lymphocyte response to viral infection during fetal life

scientific article

Medicine. The need for a global HIV vaccine enterprise

scientific article

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

scientific article published in April 2002

Memory T cells established by seasonal human influenza A infection cross-react with avian influenza A (H5N1) in healthy individuals

scientific article

Memory T cells established by seasonal human influenza A infection cross-react with avian influenza A (H5N1) in healthy individuals ⬇️

scientific article published in November 2012

Modified vaccinia Ankara expressing HIVA antigen stimulates HIV-1-specific CD8 T cells in ELISpot assays of HIV-1 exposed infants

scientific article

Molecular signatures distinguish human central memory from effector memory CD8 T cell subsets

scientific article

Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity

scientific article published on 28 March 2022

Mucosal immunization with PLGA-microencapsulated DNA primes a SIV-specific CTL response revealed by boosting with cognate recombinant modified vaccinia virus Ankara

scientific article published in August 2003

Multilayered defense in HLA-B51-associated HIV viral control

scientific article

Natural T Cell-mediated Protection against Seasonal and Pandemic Influenza. Results of the Flu Watch Cohort Study

scientific article

Nef-mediated lipid raft exclusion of UbcH7 inhibits Cbl activity in T cells to positively regulate signaling

scientific article published on December 2005

New templates for HIV-1 antibody-based vaccine design

scientific article

Novel Conserved-region T-cell Mosaic Vaccine With High Global HIV-1 Coverage Is Recognized by Protective Responses in Untreated Infection

scientific article published on 08 January 2016

Novel HIV-1 clade B candidate vaccines designed for HLA-B*5101(+) patients protected mice against chimaeric ecotropic HIV-1 challenge

scientific article published on 01 July 2009

Optimal vaccination strategies for 2009 pandemic H1N1 and seasonal influenza vaccines in humans ⬇️

scientific article published on December 2, 2010

Optimization of peptide linker length in production of MHC class II/peptide tetrameric complexes increases yield and stability, and allows identification of antigen-specific CD4+T cells in peripheral blood mononuclear cells

scientific article published on 01 December 2002

Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding

scientific article published in Nature Communications

Persistent HIV-1-specific cellular responses despite prolonged therapeutic viral suppression

scientific article published in January 2002

Phase I clinical trial safety of DNA- and modified virus Ankara-vectored human immunodeficiency virus type 1 (HIV-1) vaccines administered alone and in a prime-boost regime to healthy HIV-1-uninfected volunteers

scientific article

Phenotypic analysis of antigen-specific T lymphocytes. Science. 1996. 274: 94-96.

scientific article

Pivotal Advance: Invariant NKT cells reduce accumulation of inflammatory monocytes in the lungs and decrease immune-pathology during severe influenza A virus infection ⬇️

scientific article published on October 14, 2011

Polyfunctional T cell responses are a hallmark of HIV-2 infection

scientific article published on February 2008

Preexisting compensatory amino acids compromise fitness costs of a HIV-1 T cell escape mutation

scientific article

Preferential detection of HIV subtype C' over subtype A in cervical cells from a dually infected woman

scientific article published on 01 June 2005

Prime-boost regimens with adjuvanted synthetic long peptides elicit T cells and antibodies to conserved regions of HIV-1 in macaques

article

Proof-of-Principle for Immune Control of Global HIV-1 Reactivation In Vivo

scientific article published on 16 March 2015

Prospects for an AIDS vaccine.

scientific article

Protective efficacy of serially up-ranked subdominant CD8+ T cell epitopes against virus challenges

scientific article

Proteome-wide analysis of HIV-specific naive and memory CD4(+) T cells in unexposed blood donors

scientific article

Quantitating T cell cross-reactivity for unrelated peptide antigens

scientific article (publication date: October 2009)

Quantitative and qualitative differences in the T cell response to HIV in uninfected Ugandans exposed or unexposed to HIV-infected partners

scientific article published on 12 June 2013

Rational development of high-affinity T-cell receptor-like antibodies

scientific article

Reappraisal of the relationship between the HIV-1-protective single-nucleotide polymorphism 35 kilobases upstream of the HLA-C gene and surface HLA-C expression

scientific article

Recombination-mediated escape from primary CD8+ T cells in acute HIV-1 infection.

scientific article

Reduction of natural killer but not effector CD8 T lymphocytes in three consecutive cases of severe/lethal H1N1/09 influenza A virus infection

scientific article

Reflecting on a quarter century of HIV research

article

Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection

scientific article

Relative rate and location of intra-host HIV evolution to evade cellular immunity are predictable

scientific article published on 23 May 2016

Requirement of the proteasome for the trimming of signal peptide-derived epitopes presented by the nonclassical major histocompatibility complex class I molecule HLA-E

scientific article (publication date: 5 September 2003)

Reversion and T cell escape mutations compensate the fitness loss of a CD8+ T cell escape mutant in their cognate transmitted/founder virus

scientific article

Robust Gag-specific T cell responses characterize viremia control in HIV-2 infection

scientific article published in October 2007

ST111 Immune selection and vpu variability in a unique narrow source HIV-Positive village cohort

article

Safety and immunogenicity of recombinant low-dosage HIV-1 A vaccine candidates vectored by plasmid pTHr DNA or modified vaccinia virus Ankara (MVA) in humans in East Africa

scientific article published on 31 March 2008

Safety and tolerability of recombinant modified vaccinia virus Ankara expressing an HIV-1 gag/multiepitope immunogen (MVA.HIVA) in HIV-1-infected persons receiving combination antiretroviral therapy

scientific article published on 11 January 2007

Screening for HIV-specific T-cell responses using overlapping 15-mer peptide pools or optimized epitopes

scientific article published in July 2004

Sequential broadening of CTL responses in early HIV-1 infection is associated with viral escape ⬇️

scientific article published on 21 February 2007

Specificity of T cells in synovial fluid: high frequencies of CD8(+) T cells that are specific for certain viral epitopes

scientific article

Strategies for an HIV cure: progress and challenges

article

Strong TCR conservation and altered T cell cross-reactivity characterize a B*57-restricted immune response in HIV-1 infection

scientific article published on September 2006

Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms

scientific article

Structures of three HIV-1 HLA-B*5703-peptide complexes and identification of related HLAs potentially associated with long-term nonprogression.

scientific article published in August 2005

Studies of a prophylactic HIV-1 vaccine candidate based on modified vaccinia virus Ankara (MVA) with and without DNA priming: effects of dosage and route on safety and immunogenicity

scientific article published on 27 November 2006

T cell cross-reactivity and conformational changes during TCR engagement

scientific article

T cell responses in dengue hemorrhagic fever: are cross-reactive T cells suboptimal?

scientific article

T cell responses to whole SARS coronavirus in humans

scientific article published on October 2008

T cell selection during the evolution of CD8+ T cell memory in vivo

scientific article published in December 1998

Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection

scientific article

Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased in ankylosing spondylitis

scientific article published on 19 January 2011

The Duffy antigen receptor for chemokines null promoter variant does not influence HIV-1 acquisition or disease progression

scientific article

The HIV protease inhibitor indinavir reduces immature dendritic cell transendothelial migration.

scientific article published in September 2003

The Role of MHC-E in T Cell Immunity Is Conserved among Humans, Rhesus Macaques, and Cynomolgus Macaques

scientific article published on 17 November 2017

The T cell repertoire in infection and vaccination: implications for control of persistent viruses

scientific article published on 12 April 2007

The T cell surface--how well do we know it?

scientific article

The antiviral efficacy of HIV-specific CD8⁺ T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate

scientific article

The clonal expression of antibody-forming cells.

PhD Thesis of Andrew McMichael

The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection

scientific article published on June 2009

The immune response during acute HIV-1 infection: clues for vaccine development

scientific article

The presence of prolines in the flanking region of an immunodominant HIV-2 gag epitope influences the quality and quantity of the epitope generated.

scientific article published on 28 May 2015

The quest for an AIDS vaccine: is the CD8+ T-cell approach feasible?

scientific article

The structural dynamics and energetics of an immunodominant T cell receptor are programmed by its Vbeta domain

scientific article

Therapeutic immunization of highly active antiretroviral therapy-treated HIV-1-infected patients: safety and immunogenicity of an HIV-1 gag/poly-epitope DNA vaccine

scientific article published on 01 August 2005

Topological perspective on HIV escape

scientific article

Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection

scientific article

Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing

scientific article

Unusual antigen presentation offers new insight into HIV vaccine design

scientific article

Use of B cell-bound HLA-A2 class I monomers to generate high-avidity, allo-restricted CTLs against the leukemia-associated protein Wilms tumor antigen

scientific article published on 26 February 2004

Vaccination with a modified vaccinia virus Ankara (MVA)-vectored HIV-1 immunogen induces modest vector-specific T cell responses in human subjects

scientific article published on 16 September 2010

Vaccine route, dose and type of delivery vector determine patterns of primary CD8+ T cell responses

scientific article published in September 2005

Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1.

scientific article published on 31 October 2013

Vaccines that stimulate T cell immunity to HIV-1: the next step

scientific article

Vertical T cell immunodominance and epitope entropy determine HIV-1 escape

scientific article

Workshop Summary: Novel Biomarkers for HIV Incidence Assay Development ⬇️

scientific article published on February 24, 2012

Paulina is supported by:

About Paulina

Help