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List of works by Jack E. Dixon

A PTEN-like phosphatase with a novel substrate specificity

scientific journal article

A PTEN-related 5-phosphatidylinositol phosphatase localized in the Golgi

scientific article published on 23 July 2003

A Single Kinase Generates the Majority of the Secreted Phosphoproteome

scientific article

A Unique Carbohydrate Binding Domain Targets the Lafora Disease Phosphatase to Glycogen ⬇️

scientific article published on December 5, 2001

A Yersinia effector and a Pseudomonas avirulence protein define a family of cysteine proteases functioning in bacterial pathogenesis.

scientific article published on May 2002

A conserved phosphatase cascade that regulates nuclear membrane biogenesis

scientific article

A distinctive role for the Yersinia protein kinase: actin binding, kinase activation, and cytoskeleton disruption.

scientific article

A family of bacterial cysteine protease type III effectors utilizes acylation-dependent and -independent strategies to localize to plasma membranes.

scientific article published on 03 April 2009

A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast

scientific article

A ligand-induced conformational change in the Yersinia protein tyrosine phosphatase

scientific article published on September 1995

A mutation in adenylosuccinate lyase associated with mental retardation and autistic features

scientific article (publication date: April 1992)

A new role for sphingosine: Up-regulation of Fam20C, the genuine casein kinase that phosphorylates secreted proteins.

scientific article published on 30 April 2015

A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.

scholarly article

A procedure for in situ alkylation of cystine residues on glass fiber prior to protein microsequence analysis

scientific article published on 01 March 1987

A protein phosphatase related to the vaccinia virus VH1 is encoded in the genomes of several orthopoxviruses and a baculovirus

scientific article

A reply from HHMI.

scientific article

A reply from Howard Hughes Medical Institute (HHMI)

scientific article

A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease

scientific article

A secreted tyrosine kinase acts in the extracellular environment

scientific article

A secretory kinase complex regulates extracellular protein phosphorylation

scientific article

A secretory pathway kinase regulates sarcoplasmic reticulum Ca homeostasis and protects against heart failure

scientific article published on 06 December 2018

A sensitive assay for phosphoinositide phosphatases

scientific article published on 01 March 2000

A single mutation converts a novel phosphotyrosine binding domain into a dual-specificity phosphatase.

scientific article

A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate

scholarly article

A yeast protein phosphatase related to the vaccinia virus VH1 phosphatase is induced by nitrogen starvation ⬇️

scientific article published on December 15, 1992

Active site labeling of a receptor-like protein tyrosine phosphatase

scientific article published on 01 January 1992

An assay for phosphoinositide phosphatases utilizing fluorescent substrates

scientific article published in August 2001

Analysis of Rho-GTPase mimicry by a family of bacterial type III effector proteins

scientific article

Ancestral Roles of the Fam20C Family of Secreted Protein Kinases Revealed by Functional Analysis in C. elegans

Ancestral roles of the Fam20C family of secreted protein kinases revealed in C. elegans

scientific article published on 20 September 2019

Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2

scientific article published on 09 July 2018

Binding Constant Determination Studies Utilizing Recombinant ΔCREB Protein

scientific article published on 01 March 1993

Biochemical characterization of the Yersinia YopT protease: cleavage site and recognition elements in Rho GTPases

scientific article

Biosynthesis and posttranslational processing of site-directed endoproteolytic cleavage mutants of pro-neuropeptide Y in mouse pituitary cells

scientific article published on February 1990

Catalytic mechanism of the phospholipase D superfamily proceeds via a covalent phosphohistidine intermediate ⬇️

scientific article published on August 4, 1998

Chapter 13 Localization and function of the 2Fe-2S outer mitochondrial membrane protein mitoNEET.

scientific article published in January 2009

Cleavage of Arabidopsis PBS1 by a bacterial type III effector

scientific article (publication date: 29 August 2003)

Climate change and the integrity of science

scientific article

Cloning and sequence analysis of a cDNA encoding rat preprocholecystokinin

scientific article

Cloning, characterization, and sequence of a porcine cDNA encoding a secreted neuronal and endocrine protein

scientific article

Cloning, expression, and characterization of the Galalpha 1,3Gal high affinity lectin from the mushroom Marasmius oreades

scientific article

Clostridiolysin S, a post-translationally modified biotoxin from Clostridium botulinum

scientific article

Comparative analysis of Histophilus somni immunoglobulin-binding protein A (IbpA) with other fic domain-containing enzymes reveals differences in substrate and nucleotide specificities

scientific article

Components of a new human protein kinase signal transduction pathway

scientific article

Cotranslational and posttranslational proteolytic processing of preprosomatostatin-I in intact islet tissue

scientific article

Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 A and the complex with tungstate

scientific article

Crystal structure of a phosphoinositide phosphatase, MTMR2: insights into myotubular myopathy and Charcot-Marie-Tooth syndrome

scientific article

Crystal structure of a phospholipase D family member

scientific article

Crystal structure of the Golgi casein kinase ⬇️

scientific article published on June 10, 2013

Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

scientific article

Crystal structure of the dual specificity protein phosphatase VHR

scientific article

Crystallization and preliminary structural analysis of Bacillus subtilis adenylosuccinate lyase, an enzyme implicated in infantile autism

scientific article

De novo purine nucleotide biosynthesis

scientific article published on January 1, 1992

Determinants for Dephosphorylation of the RNA Polymerase II C-Terminal Domain by Scp1

scientific article

Discovery of a widely distributed toxin biosynthetic gene cluster

scholarly article

Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease.

scientific article

Dissecting the catalytic mechanism of protein-tyrosine phosphatases

scientific article

Distinguishing mitochondrial inner membrane orientation of dual specific phosphatase 18 and 21.

scientific article published in January 2009

Distribution and regulation of the candidate prohormone processing enzymes SPC2 and SPC3 in adult rat brain

scientific article published on 01 December 1994

Distribution of carboxypeptidase H messenger RNA in rat brain using in situ hybridization histochemistry: implications for neuropeptide biosynthesis

scientific article published on 01 January 1990

Drosophila Ack Targets Its Substrate, the Sorting Nexin DSH3PX1, to a Protein Complex Involved in Axonal Guidance ⬇️

scientific article published on December 28, 2001

Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity

scientific article (publication date: 9 June 2000)

Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane

scientific journal article

Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis

scientific article

ERK7 is an autoactivated member of the MAPK family

scientific journal article

Enzymatic Phosphorylation of Ser in a Type I Collagen Peptide

scientific article published on 16 November 2018

Exclusion of close linkage between the loci for cystic fibrosis and neuropeptide Y on human chromosome 7

scientific article published on 01 January 1987

Expansion of type II CAAX proteases reveals evolutionary origin of γ-secretase subunit APH-1

scientific article

Form, function, and regulation of protein tyrosine phosphatases and their involvement in human diseases.

scientific article

Functions of the Yersinia effector proteins in inhibiting host immune responses

scientific article

Genes encoding pancreatic polypeptide and neuropeptide Y are on human chromosomes 17 and 7

scientific article

Genomics and evolution of protein phosphatases

scientific article

Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis

scientific article published on October 1996

Glial cell line-derived neurotrophic factor signals through the RET receptor and activates mitogen-activated protein kinase

scientific article published on September 1996

Glycogen Synthase: An Old Enzyme with a New Trick ⬇️

scientific article published on March 2, 2011

His68 and His141 are critical contributors to the intersubunit catalytic site of adenylosuccinate lyase of Bacillus subtilis

scientific article

Identification and Characterization of GFRα-3, a Novel Co-receptor Belonging to the Glial Cell Line-derived Neurotrophic Receptor Family ⬇️

scientific article published on February 6, 1998

Identification of His141 in the active site of Bacillus subtilis adenylosuccinate lyase by affinity labeling with 6-(4-bromo-2,3-dioxobutyl)thioadenosine 5'-monophosphate

scientific journal article

Identification of a bacterial type III effector family with G protein mimicry functions.

scientific article published on January 2006

Identification of a mammalian-type phosphatidylglycerophosphate phosphatase in the Eubacterium Rhodopirellula baltica

scientific article published on 4 January 2013

Identification of a molecular target for the Yersinia protein kinase A.

scientific article published on May 2007

Identification of otubain 1 as a novel substrate for the Yersinia protein kinase using chemical genetics and mass spectrometry

scientific article

Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression

scientific article published on 21 November 2019

Inhibition of the mitogen-activated protein kinase kinase superfamily by a Yersinia effector

scientific article (publication date: 17 September 1999)

Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin

scientific article

Interactions of bacterial effector proteins with host proteins.

scientific article

Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic beta cells.

scientific article

Lafora disease: insights into neurodegeneration from plant metabolism

scientific article published on 07 October 2009

Laforin, a dual specificity phosphatase that dephosphorylates complex carbohydrates

scientific journal article

Loss of the inactive myotubularin-related phosphatase Mtmr13 leads to a Charcot-Marie-Tooth 4B2-like peripheral neuropathy in mice

scholarly article

Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG)

scientific article

Microbiology. Bacteria seize control by acetylating host proteins

scientific article published on May 2006

MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone

scientific article

MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity

scientific journal article

Mitochondrial modulation: reversible phosphorylation takes center stage?

scientific article

Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis

scientific journal article

Modulation of cholecystokinin gene expression

scientific article published on 01 January 1985

Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome.

scientific article

Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase

scientific article

Monitoring phosphorylation of the pyruvate dehydrogenase complex.

scientific article published on 31 March 2009

Myotubularin and MTMR2, Phosphatidylinositol 3-Phosphatases Mutated in Myotubular Myopathy and Type 4B Charcot-Marie-Tooth Disease ⬇️

scientific article published on December 3, 2001

Myotubularin phosphatases: policing 3-phosphoinositides

scientific article published on 7 July 2006

Myotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphate

scientific article

New fluorogenic substrates for a rat brain proline endopeptidase

scientific article published on 01 June 1980

Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry

scientific article published on 27 February 2012

Nuclear envelope phosphatase 1-regulatory subunit 1 (formerly TMEM188) is the metazoan Spo7p ortholog and functions in the lipin activation pathway

scientific article

Oncogenic RET receptors display different autophosphorylation sites and substrate binding specificities

scientific article

Overview of the Alliance for Cellular Signaling

scientific article

POMK regulates dystroglycan function via LARGE-mediated elongation of matriglycan

scientific article published on 25 September 2020

PTEN Protects p53 from Mdm2 and Sensitizes Cancer Cells to Chemotherapy ⬇️

scientific article published on November 29, 2001

PTEN and myotubularin phosphatases: from 3-phosphoinositide dephosphorylation to disease

scientific article (publication date: December 2002)

PTEN and myotubularin phosphoinositide phosphatases: bringing bioinformatics to the lab bench

scientific article

PTEN and myotubularin: novel phosphoinositide phosphatases

scientific article

PTEN and myotubularins: families of phosphoinositide phosphatases

scientific article published on January 2003

PTEN.

scientific article

PTEN: a tumour suppressor that functions as a phospholipid phosphatase

scientific article

Pharmacological targeting of the mitochondrial phosphatase PTPMT1.

scientific article

Phenol soluble modulin (PSM) variants of community-associated methicillin-resistant Staphylococcus aureus (MRSA) captured using mass spectrometry-based molecular networking

scientific article

Phosphoinositide phosphatases: emerging roles as voltage sensors?

scientific article

Phosphorylation of serine96 of histidine-rich calcium-binding protein by the Fam20C kinase functions to prevent cardiac arrhythmia.

scientific article published on 7 August 2017

Phosphorylation of spore coat proteins by a family of atypical protein kinases.

scientific article published on 16 May 2016

Phosphorylation of substrates destined for secretion by the Fam20 kinases

scientific article published on August 2013

Phoxy lipids: revealing PX domains as phosphoinositide binding modules

scientific article (publication date: 29 June 2001)

Precursors to regulatory peptides: their proteolytic processing

scientific article published on July 1987

Primary structural comparison of the preprohormones cholecystokinin and gastrin

scientific article published on 01 March 1985

Protection of mice against H. somni septicemia by vaccination with recombinant immunoglobulin binding protein subunits

scientific article published on 30 June 2008

Protein Tyrosine Phosphatases

Protein Tyrosine Phosphatases

Protein tyrosine phosphatases in the human genome

scientific article

Purification and characterization of a 43-kDa transcription factor required for rat somatostatin gene expression

scientific article published in Journal of Biological Chemistry

RNA Interference of Gene Expression (RNAi) in Cultured Drosophila Cells ⬇️

scientific article published on August 14, 2001

RNA interference in cultured Drosophila cells

scientific article published on February 2004

Regulation of myotubularin-related (MTMR)2 phosphatidylinositol phosphatase by MTMR5, a catalytically inactive phosphatase

scientific article

Response to Wang et al.: Secreted protein kinases?

scientific article

Reversible phosphorylation of Rpn1 regulates 26S proteasome assembly and function

scientific article published on 16 December 2019

Reversible phosphorylation: a birthday tribute to Herb Tabor

scientific article published on 01 February 2019

Secreted Kinase Phosphorylates Extracellular Proteins That Regulate Biomineralization ⬇️

scientific article published on May 10, 2012

Secreted protein kinases

scientific article

Selective activation of MEK1 but not MEK2 by A-Raf from epidermal growth factor-stimulated Hela cells

scientific article

Sequence analysis of a cDNA coding for a pancreatic precursor to somatostatin

scientific article

Sequence of a cDNA encoding pancreatic preprosomatostatin-22.

scientific article

Site-specific proteasome phosphorylation controls cell proliferation and tumorigenesis

scientific article published on 14 December 2015

Sorting out the cellular functions of sorting nexins

scientific article (publication date: December 2002)

Spatial control of phospholipid flux restricts endoplasmic reticulum sheet formation to allow nuclear envelope breakdown

scientific article published on January 2014

Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis

scientific article

Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1

scientific article

Structural and functional dissection of the heterocyclic peptide cytotoxin streptolysin S.

scientific article

Structural basis of Fic-mediated adenylylation

scientific article

Structure and evolution of the Fam20 kinases.

scientific article published on 23 March 2018

Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation

scientific article

Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-binding

scientific article

Structure of protein O-mannose kinase reveals a unique active site architecture.

scientific article

Substrate specificity of the protein tyrosine phosphatases

scientific article

Subversion of myosin function by E. coli.

scientific article

The 26S proteasome: A cell cycle regulator regulated by cell cycle

scientific article

The PPS1 gene of Saccharomyces cerevisiae codes for a dual specificity protein phosphatase with a role in the DNA synthesis phase of the cell cycle

scientific article

The PTEN tumor suppressor protein inhibits tumor necrosis factor-induced nuclear factor kappa B activity

scientific article published on 16 May 2001

The Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein families

scientific article published in March 2007

The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production

scientific article

The catalytic role of aspartic acid-92 in a human dual-specific protein-tyrosine-phosphatase

scientific article published on 01 March 1995

The crystal structure of Pseudomonas avirulence protein AvrPphB: A papain-like fold with a distinct substrate-binding site

scientific article

The crystal structure of adenylosuccinate lyase from Pyrobaculum aerophilum reveals an intracellular protein with three disulfide bonds

scientific article

The fic domain: regulation of cell signaling by adenylylation

scientific article

The human Cdc14 phosphatases interact with and dephosphorylate the tumor suppressor protein p53.

scientific article

The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster

scientific article published on 21 June 2007

The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancers

scientific article

The phosphatase laforin crosses evolutionary boundaries and links carbohydrate metabolism to neuronal disease.

scientific article

The phosphoinositide-3-phosphatase MTMR2 associates with MTMR13, a membrane-associated pseudophosphatase also mutated in type 4B Charcot-Marie-Tooth disease

scientific article

The purification and characterization of a human dual-specific protein tyrosine phosphatase

scientific article

The sorting nexin, DSH3PX1, connects the axonal guidance receptor, Dscam, to the actin cytoskeleton

scientific article

The stress-responsive kinase DYRK2 activates heat shock factor 1 promoting resistance to proteotoxic stress

scientific article published on 02 December 2020

The structure and regulation of myotubularin phosphatases

scientific article

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

scientific article

The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways.

scientific article

The use of a heptadeoxyribonucleotide as a specific primer for prolactin mRNA: A prediction of ambiguous RNA splicing ⬇️

scientific article published on October 15, 1981

The yeast open reading frame encoding a dual specificity phosphatase

scientific article published on January 1993

The yersinia virulence factor YopM forms a novel protein complex with two cellular kinases

scientific article (publication date: 16 May 2003)

Three sequence-specific DNA-protein complexes are formed with the same promoter element essential for expression of the rat somatostatin gene

scientific article published on May 1988

Tissue-Specific and Substrate-Specific Endoproteolytic Cleavage of Monkey Pro-Opiomelanocortin in Heterologous Endocrine Cells: Processing at Lys-Lys Dibasic Pairs

Transfected human neuropeptide Y cDNA expression in mouse pituitary cells. Inducible high expression, peptide characterization, and secretion

scientific article

Two precursors of melanin-concentrating hormone: DNA sequence analysis and in situ immunochemical localization

scientific article

Tyrosine phosphate hydrolysis of host proteins by an essential Yersinia virulence determinant

scientific article published on February 1991

UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity ⬇️

scientific article published on September 26, 2011

Unpacking the unfolded protein response

scientific article published in September 2014

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.

scientific article published on June 2000

Use of double-stranded RNA-mediated interference to determine the substrates of protein tyrosine kinases and phosphatases

scientific article published in August 2002

Visualisation of messenger RNA directing peptide synthesis by in situ hybridisation using a novel single-stranded cDNA probe. Potential for the investigation of gene expression and endocrine cell activity

scientific article published on 01 January 1984

Visualization of intermediate and transition-state structures in protein-tyrosine phosphatase catalysis

scientific article published on March 1996

Voltage-Sensing Phosphatase: Its Molecular Relationship With PTEN ⬇️

scientific article published on February 1, 2011

Widespread dynamic DNA methylation in response to biotic stress ⬇️

scientific article published on June 25, 2012

Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis

scientific article published on 24 May 2013

Xylose phosphorylation functions as a molecular switch to regulate proteoglycan biosynthesis

scientific journal article

Yersinia effectors target mammalian signalling pathways

scientific article

[PTEN tumor suppressor: functions as a lipid phosphatase]

scientific article published on 01 October 2000

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