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List of works by Iain William Mattaj

40LoVe interacts with Vg1RBP/Vera and hnRNP I in binding the Vg1-localization element

scientific article

42S p48--the most abundant protein in previtellogenic Xenopus oocytes--resembles elongation factor 1 alpha structurally and functionally

scientific article

A binding consensus: RNA-protein interactions in splicing, snRNPs, and sex.

scientific article published on April 1989

A cap binding protein that may mediate nuclear export of RNA polymerase II-transcribed RNAs

scientific article published on September 1992

A common octamer motif binding protein is involved in the transcription of U6 snRNA by RNA polymerase III and U2 snRNA by RNA polymerase II.

scientific article published on October 1987

A compartmentalized phosphorylation/dephosphorylation system that regulates U snRNA export from the nucleus

scientific article published on 29 October 2007

A complex secondary structure in U1A pre-mRNA that binds two molecules of U1A protein is required for regulation of polyadenylation

scientific article

A factor with Sp1 DNA-binding specificity stimulates Xenopus U6 snRNA in vivo transcription by RNA polymerase III.

scientific article published in November 1992

A nuclear cap binding protein complex involved in pre-mRNA splicing

scientific article

A nuclear cap-binding complex facilitates association of U1 snRNP with the cap-proximal 5' splice site.

scientific article published in July 1996

A role for NuSAP in linking microtubules to mitotic chromosomes

scientific article published on February 2007

A role for gp210 in mitotic nuclear-envelope breakdown.

scientific article

A role for the M9 transport signal of hnRNP A1 in mRNA nuclear export

scientific article

A selective review of RNA-protein interactions in eukaryotes ⬇️

scientific article published on January 1, 1990

A transcription factor which binds to the enhancers of SV40, immunoglobulin heavy chain and U2 snRNA genes

scientific article published in Nature

A weak interaction between the U2A' protein and U2 snRNA helps to stabilize their complex with the U2B" protein

scientific article published on February 1991

A yeast cap binding protein complex (yCBC) acts at an early step in pre-mRNA splicing.

scientific article

An ATP-dependent activity that releases RanGDP from NTF2.

scientific article

An abundant U6 snRNP found in germ cells and embryos of Xenopus laevis

scientific article

An enhancer-like sequence within the Xenopus U2 gene promoter facilitates the formation of stable transcription complexes

scientific article published in Nature

Analysis of in vitro binding of U1-A protein mutants to U1 snRNA.

scientific article

Analysis of the in vitro binding of A and B″ snRNP proteins to U1 and U2 snRNAs using mutated A and B″ proteins

scientific article published on 01 January 1990

Anti-(U1) small nuclear RNA antibodies in anti-small nuclear ribonucleoprotein sera from patients with connective tissue diseases

scientific article published on December 1990

Anti-OTF-1 antibodies inhibit NFIII stimulation of in vitro adenovirus DNA replication

scientific article

Architecture of CRM1/Exportin1 suggests how cooperativity is achieved during formation of a nuclear export complex

scientific article

Binding specificity determinants of U1A and U2B″ proteins

scientific article published on 01 January 1990

CHD4 is a RanGTP-dependent MAP that stabilizes microtubules and regulates bipolar spindle formation

scientific article published on 21 November 2013

Caenorhabditis elegans BAF-1 and its kinase VRK-1 participate directly in post-mitotic nuclear envelope assembly

scientific article published on 14 December 2006

Caenorhabditis elegans nucleoporins Nup93 and Nup205 determine the limit of nuclear pore complex size exclusion in vivo

scientific article

Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate

scientific article

Changing the RNA polymerase specificity of U snRNA gene promoters

scientific article published in November 1988

Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells

scientific article (publication date: November 2002)

Cloning in a cosmid vector of complete 37 kb and 25 kb ribosomal DNA repeat units from the chicken

scientific article published on August 1982

Cloning of nucleoplasmin from Xenopus laevis oocytes and analysis of its developmental expression

scientific article

Co-crystallization of the human nuclear cap-binding complex with a m7GpppG cap analogue using protein engineering

scientific article

Cofractionation of the TATA-binding protein with the RNA polymerase III transcription factor TFIIIB.

scientific article published on November 1992

Comments from the European Molecular Biology Laboratory

scientific article published in July 2008

Common and unique transcription factor requirements of human U1 and U6 snRNA genes

scientific journal article

Complex requirements for RNA polymerase III transcription of the Xenopus U6 promoter

scientific article published on October 1990

Conserved amino acid residues within and outside of the N-terminal ribonucleoprotein motif of U1A small nuclear ribonucleoprotein involved in U1 RNA binding

scientific article published in June 1991

Conserved loop I of U5 small nuclear RNA is dispensable for both catalytic steps of pre-mRNA splicing in HeLa nuclear extracts.

scientific article

Coordinated action needed for Europe's research programmes

scientific article published in Nature

Coordination of kinase and phosphatase activities by Lem4 enables nuclear envelope reassembly during mitosis

scientific article

Cyclosporin A is a differential inhibitor of eukaryotic RNA polymerases

scientific article published on 01 April 1984

Direct membrane protein-DNA interactions required early in nuclear envelope assembly

scientific article

Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly

scientific article

Diversity in the signals required for nuclear accumulation of U snRNPs and variety in the pathways of nuclear transport

scientific article published on May 1991

Domains of U4 and U6 snRNAs required for snRNP assembly and splicing complementation in Xenopus oocytes

scientific article

Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex ⬇️

scientific article

Drosophila SNF/D25 combines the functions of the two snRNP proteins U1A and U2B' that are encoded separately in human, potato, and yeast

scientific article published on January 1996

EMBL's fourth decade

scientific article published in October 2005

Electron microscopy of lamin and the nuclear lamina in Caenorhabditis elegans

scientific article

Energy- and temperature-dependent in vitro export of RNA from synthetic nuclei

scientific article

Estrogen induces a demethylation at the 5' end region of the chicken vitellogenin gene

scientific article

Formation of the 3' end on U snRNAs requires at least three sequence elements.

scientific article

Functional analysis of mutant Xenopus U2 snRNAs

scientific article published on October 1989

Functional characterization of X. laevis U5 snRNA genes

scientific article

Fungal small nuclear ribonucleoproteins share properties with plant and vertebrate U-snRNPs.

scientific article

GTP hydrolysis by Ran is required for nuclear envelope assembly.

scientific article published in June 2000

Genetic and physical interactions involving the yeast nuclear cap-binding complex

scientific article

HURP is part of a Ran-dependent complex involved in spindle formation

scientific article (publication date: 18 April 2006)

Hepatoma up-regulated protein is required for chromatin-induced microtubule assembly independently of TPX2

scientific article published on 17 September 2008

Herpes simplex virus ICP27 protein provides viral mRNAs with access to the cellular mRNA export pathway.

scientific article

ISWI is a RanGTP-dependent MAP required for chromosome segregation

scientific article

Identification and characterization of RED120: a conserved PWI domain protein with links to splicing and 3'-end formation.

scientific article

Identification of 40LoVe, a Xenopus hnRNP D family protein involved in localizing a TGF-beta-related mRNA during oogenesis

scientific article (publication date: April 2005)

Identification of a nuclear export receptor for tRNA

scientific article

Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences

scientific article

Identification of the RNA binding segment of human U1 A protein and definition of its binding site on U1 snRNA.

scientific article published on December 1989

Identity elements used in export of mRNAs

scientific article

Importin alpha associates with membranes and participates in nuclear envelope assembly in vitro

scientific article

Importin alpha-regulated nucleation of microtubules by TPX2.

scientific article

Importin provides a link between nuclear protein import and U snRNA export

scientific article published in October 1996

In vitro assembly of U1 snRNPs

scientific article

Intracellular distribution of the U1A protein depends on active transport and nuclear binding to U1 snRNA.

scientific article published in July 1992

Involvement of the carboxyl terminus of vertebrate poly(A) polymerase in U1A autoregulation and in the coupling of splicing and polyadenylation

scientific article published on 01 March 1997

Isolation and fine structure organisation of an avian vitellogenin gene coding for the major estrogen-inducible mRNA.

scientific article published on December 1981

It's the Technology, Stupid ⬇️

scientific article published on November 15, 2010

Large-scale induced fit recognition of an m(7)GpppG cap analogue by the human nuclear cap-binding complex

scientific article

Laying solid foundations for Europe

scientific article published in Nature

Lipin is required for efficient breakdown of the nuclear envelope in Caenorhabditis elegans

scientific article published in June 2009

Localisation of a strongly conserved section of coding sequence in glutamate dehydrogenase genes.

scientific article published in October 1982

Loop I of U1 small nuclear RNA is the only essential RNA sequence for binding of specific U1 small nuclear ribonucleoprotein particle proteins

scientific article published on November 1988

MEL-28, a novel nuclear-envelope and kinetochore protein essential for zygotic nuclear-envelope assembly in C. elegans

scientific article published in September 2006

MEL-28/ELYS is required for the recruitment of nucleoporins to chromatin and postmitotic nuclear pore complex assembly

scientific article published on 19 January 2007

Major determinants of the specificity of interaction between small nuclear ribonucleoproteins U1A and U2B'' and their cognate RNAs

scientific article published in June 1990

Meiosis: MeiRNA hits the spot

scientific article

Mitotic lamin disassembly is triggered by lipid-mediated signaling

scientific article

Monomethylated cap structures facilitate RNA export from the nucleus

scientific article published in October 1990

Monospecific antibodies reveal details of U2 snRNP structure and interaction between U1 and U2 snRNPs

scientific article

Multiple domains of U1 snRNA, including U1 specific protein binding sites, are required for splicing

scientific article

Mutant U2 snRNAs of Xenopus which can form an altered higher order RNA structure are unable to enter the nucleus

scientific article published on 01 October 1987

NLS-mediated NPC functions of the nucleoporin Pom121

scientific article published on 14 July 2010

New pieces in the U5 puzzle

scientific article

NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules

scientific article

Nuclear biology: what's been most surprising?

scientific article published on March 2013

Nuclear exclusion of transcription factor IIIA and the 42s particle transfer RNA-binding protein in Xenopus oocytes: a possible mechanism for gene control?

scientific article

Nuclear import of U snRNPs requires importin beta

scientific article published on November 1997

Nuclear inclusion of nontargeted and chromatin-targeted polystyrene beads and plasmid DNA containing nanoparticles

scientific article published on 22 August 2011

Nuclear localization of a cap-binding protein complex

scientific article published in January 1995

Nuclear pore complexes: round the bend?

scientific article

Nuclear retention of RNA as a mechanism for localization.

scientific article published on May 1995

Nuclear segregation of U2 snRNA requires binding of specific snRNP proteins

scientific article published in January 1985

Nuclear transport of the U2 snRNP-specific U2B'' protein is mediated by both direct and indirect signalling mechanisms.

scientific article

Nucleocytoplasmic transport and snRNP assembly

scientific article

Nucleocytoplasmic transport: Ran, beta and beyond

scientific article

Nucleocytoplasmic transport: the last 200 nanometers

scientific article published on February 1998

Nucleocytoplasmic transport: the soluble phase

scientific article (publication date: 1998)

Nucleoporins NPP-1, NPP-3, NPP-4, NPP-11 and NPP-13 are required for proper spindle orientation in C. elegans

scientific article

Nucleus and gene expression

article

Nup155 regulates nuclear envelope and nuclear pore complex formation in nematodes and vertebrates

scientific article

Nup53 is required for nuclear envelope and nuclear pore complex assembly

scientific article published on 6 February 2008

Only two of the four sites of interaction with nuclear factors within the Xenopus U2 gene promoter are necessary for efficient transcription

scientific article

Position-dependent inhibition of the cleavage step of pre-mRNA 3'-end processing by U1 snRNP

scientific article

Positionally exact initiation is required for the formation of a stable RNA polymerase II transcription complex in vivo

scientific article published on December 1988

Positive and negative functional interactions between promoter elements from different classes of RNA polymerase III-transcribed genes

scientific article published on April 1990

Properties of a U1 RNA enhancer-like sequence

scientific article

Proximal sequence element factor binding and species specificity in vertebrate U6 snRNA promoters

article

Pushing the envelope: structure, function, and dynamics of the nuclear periphery

scientific article

Quantitative models of nuclear transport

scientific article

RAN/TC4 mutants identify a common requirement for snRNP and protein import into the nucleus

scientific article published on May 1996

RNA export

scientific article published on April 1995

RNA processing. Splicing in space.

scientific article

RNA recognition: a family matter?

scientific article

RNA-protein interactions

scientific article published on 01 December 1991

Ran GTPase cycle and importins alpha and beta are essential for spindle formation and nuclear envelope assembly in living Caenorhabditis elegans embryos

scientific article

Ran binds to chromatin by two distinct mechanisms.

scientific article

Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity

scientific article published in January 2001

Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly

scientific article published in March 2001

RanBP3 influences interactions between CRM1 and its nuclear protein export substrates

scientific article

RanGTP mediates nuclear pore complex assembly

scientific article

RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicase

scientific article

Receptor-mediated substrate translocation through the nuclear pore complex without nucleotide triphosphate hydrolysis

scientific article published on 01 January 1999

Recruiting proteins to the RNA world

scientific article published in July 1995

Regulated splicing in early development and stage-specific U snRNPs

scientific article

Retrospective. Lennart Philipson (1929-2011).

scientific article

Ribonucleoprotein assembly: Clues from spinal muscular atrophy ⬇️

scientific article published on January 29, 1998

Ribonucleoprotein particles in cellular processes

scientific article

Roles of U4 and U6 snRNAs in the assembly of splicing complexes.

scientific article published on January 1992

Small nuclear RNA-protein complexes

scientific article published on 01 December 1988

Small nuclear RNAs in messenger RNA and ribosomal RNA processing.

scientific article published on January 1993

Snail mail to the nucleus

scientific article published in Nature

Solving the NES problem ⬇️

scientific article published on November 1, 2010

Sorting out the nuclear envelope from the endoplasmic reticulum

scientific article published on January 2004

Splicing stories and poly(A) tales: an update on RNA processing and transport

scientific article published on June 1990

Steady-state nuclear localization of exportin-t involves RanGTP binding and two distinct nuclear pore complex interaction domains

scientific article

Structural analysis of U small nuclear ribonucleoproteins by in vitro assembly

scientific article published on 01 January 1990

Structure and expression of a Xenopus gene encoding an snRNP protein (U1 70K).

scientific article published on December 1988

Structure and sequence of the promoter area and of a 5' upstream demethylation site of the estrogen-regulated chicken vitellogenin ii gene

scientific article published in July 1983

Structure-function in Xenopus snRNPs

scientific article published on 01 January 1990

TFIID is required for in vitro transcription of the human U6 gene by RNA polymerase III.

scientific article published on July 1991

The Integral Membrane Nucleoporin pom121 Functionally Links Nuclear Pore Complex Assembly and Nuclear Envelope Formation

scientific article published on 01 January 2005

The NMR structure of the 38 kDa U1A protein - PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein

scientific article

The Nup107-160 nucleoporin complex promotes mitotic events via control of the localization state of the chromosome passenger complex

scientific article published on December 2009

The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly

scientific article

The SMN complex is associated with snRNPs throughout their cytoplasmic assembly pathway

scientific article

The U2B'' RNP motif as a site of protein-protein interaction.

scientific article published on November 1990

The Xenopus U2 gene PSE is a single, compact, element required for transcription initiation and 3' end formation.

scientific article published on May 1989

The Xenopus homeo boxes

scientific article published in January 1985

The Xenopus laevis U2 gene distal sequence element (enhancer) is composed of four subdomains that can act independently and are partly functionally redundant

scientific article published on April 1989

The Yeast Nuclear Cap Binding Complex Can Interact with Translation Factor eIF4G and Mediate Translation Initiation

scientific article published on 01 July 2000

The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus ⬇️

scientific article (publication date: 3 November 1997)

The carboxyl terminus of vertebrate poly(A) polymerase interacts with U2AF 65 to couple 3'-end processing and splicing

scientific article

The compartmentalized bacteria of the planctomycetes-verrucomicrobia-chlamydiae superphylum have membrane coat-like proteins

scientific article

The conserved Nup107-160 complex is critical for nuclear pore complex assembly

scientific article

The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells

scientific article

The cytoplasmic filaments of the nuclear pore complex are dispensable for selective nuclear protein import

scientific article

The determinants for Sm protein binding to Xenopus U1 and U5 snRNAs are complex and non-identical.

scientific article

The evolutionarily conserved region of the U snRNA export mediator PHAX is a novel RNA-binding domain that is essential for U snRNA export

scientific article

The future of research universities. Is the model of research-intensive universities still valid at the beginning of the twenty-first century?

scientific article published on September 2007

The gdhA1 point mutation in Escherichia coli K12 CLR207 alters a key lysine residue of glutamate dehydrogenase

scientific article published in August 1993

The human U1 snRNP-specific U1A protein inhibits polyadenylation of its own pre-mRNA.

scientific article

The human U1A snRNP protein regulates polyadenylation via a direct interaction with poly(A) polymerase

scientific article published on 01 February 1994

The influence of 5' and 3' end structures on pre-mRNA metabolism.

scientific article published on January 1995

The inner nuclear membrane protein Lem2 is critical for normal nuclear envelope morphology

scientific article

The nucleoporin MEL-28 promotes RanGTP-dependent γ-tubulin recruitment and microtubule nucleation in mitotic spindle formation

scientific article published in January 2014

The role of exportin-t in selective nuclear export of mature tRNAs

scientific article

The strategy for coupling the RanGTP gradient to nuclear protein export

scientific article

The trimethylguanosine cap structure of U1 snRNA is a component of a bipartite nuclear targeting signal

scientific article published on 01 August 1990

Three-dimensional reconstruction of bacteria with a complex endomembrane system

scientific article published in 2013

Transport of RNA between nucleus and cytoplasm

scientific article published on August 1, 1992

U snRNA gene families in Xenopus laevis

scientific article

U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase

scientific article published in January 1998

Visualizing nuclear export of different classes of RNA by electron microscopy.

scientific article

What can Caenorhabditis elegans tell us about the nuclear envelope?

scientific article published on 30 March 2007

Xenopus laevis U1 snRNA genes: characterisation of transcriptionally active genes reveals major and minor repeated gene families

scientific article

Xenopus laevis U2 snRNA genes: tandemly repeated transcription units sharing 5' and 3' flanking homology with other RNA polymerase II transcribed genes

scientific article

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