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List of works by Susan M. Gasser

32 Import of polypeptides into isolated yeast mitochondria

scientific article published on 01 January 1983

A Nuclear RNA Degradation Pathway Helps Silence Polycomb/H3K27me3-Marked Loci in Caenorhabditis elegans

scientific article published on 29 April 2020

A Rad53 independent function of Rad9 becomes crucial for genome maintenance in the absence of the Recq helicase Sgs1

scientific article

A Role for the Mre11-Rad50-Xrs2 Complex in Gene Expression and Chromosome Organization

scientific article published on 27 November 2020

A dual role of H4K16 acetylation in the establishment of yeast silent chromatin.

scientific article

A game of musical chairs: Pro- and anti-resection factors compete for TOPBP1 binding after DNA damage.

scientific article

A homotrimer-heterotrimer switch in Sir2 structure differentiates rDNA and telomeric silencing

scientific article published on 01 March 2006

A molecular dissection of nuclear function. Conference on the dynamic nucleus: questions and implications

scientific article published in January 2003

A regulatory phosphorylation site on Mec1 controls chromatin occupancy of RNA polymerases during replication stress

scientific article published on 27 September 2021

A sense of the end.

scientific article

ATP-dependent chromatin remodeling and DNA double-strand break repair.

scientific article

ATR/Mec1: coordinating fork stability and repair.

scientific article published on 21 February 2009

Actin-related protein Arp6 influences H2A.Z-dependent and -independent gene expression and links ribosomal protein genes to nuclear pores

scientific article

Actin-related proteins in the nucleus: life beyond chromatin remodelers.

scientific article published on 18 March 2010

Active chromatin marks drive spatial sequestration of heterochromatin in C. elegans nuclei

scientific article published on 22 May 2019

An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks

scientific article

An N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing

scientific article

Analysis of Sir2p domains required for rDNA and telomeric silencing in Saccharomyces cerevisiae.

scientific article

Analysis of nuclear organization in Saccharomyces cerevisiae

scientific article published on 01 January 1999

Argonaute NRDE-3 and MBT domain protein LIN-61 redundantly recruit an H3K9me3 HMT to prevent embryonic lethality and transposon expression

scientific article published on 10 December 2020

Assessing import of proteins into mitochondria: an overview

scientific article published on 01 January 1983

Asymmetric Processing of DNA Ends at a Double-Strand Break Leads to Unconstrained Dynamics and Ectopic Translocation

scientific article published on 01 September 2018

Automatic tracking of individual fluorescence particles: application to the study of chromosome dynamics.

scientific article published in September 2005

Biosynthesis of the ubiquinol-cytochrome c reductase complex in yeast. Characterization of precursor forms of the 44-kDa, 40-kDa and 17-kDa subunits and identification of individual messenger RNAs for these and other imported subunits of the complex

scientific article published on 01 October 1983

Caenorhabditis elegans Heterochromatin protein 1 (HPL-2) links developmental plasticity, longevity and lipid metabolism

scientific article published on 20 December 2011

Casein kinase II copurifies with yeast DNA topoisomerase II and re-activates the dephosphorylated enzyme

scientific article published on 01 February 1993

Casein kinase II phosphorylates the eukaryote-specific C-terminal domain of topoisomerase II in vivo ⬇️

scientific article published on May 1, 1992

Challenges and guidelines toward 4D nucleome data and model standards

scientific article published on 27 September 2018

Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage.

scientific article published on 12 September 2013

Chromatin and nucleosome dynamics in DNA damage and repair.

scientific article

Chromatin modifiers and remodellers in DNA repair and signalling

scientific article published on October 2017

Chromatin movement in the maintenance of genome stability.

scientific article published on March 2013

Chromatin organization and dynamics in double-strand break repair

scientific article

Chromatin states and nuclear organization in development--a view from the nuclear lamina

scientific article

Chromosome Dynamics in Response to DNA Damage

scientific article published on 12 September 2018

Chromosome dynamics: the SMC protein family ⬇️

scientific article published on April 1, 1998

Chromosome looping in yeast: telomere pairing and coordinated movement reflect anchoring efficiency and territorial organization

scientific article

Chromosome structure. Coiling up chromosomes.

scientific article published on April 1995

Chromosomes and expression mechanisms New excitement over an old word: 'chromatin'

scientific article published on 01 April 1998

Cohesin and the nucleolus constrain the mobility of spontaneous repair foci

scientific article published on 10 September 2013

Controlled exchange of chromosomal arms reveals principles driving telomere interactions in yeast

scientific article

Crosstalk between histone modifications during the DNA damage response.

scientific article

DNA Damage-Induced Nucleosome Depletion Enhances Homology Search Independently of Local Break Movement

scientific article published on 15 September 2020

DNA loops: structural and functional properties of scaffold-attached regions.

scientific article

DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1.

scientific article published on August 2003

DNA replication: Pif1 pulls the plug on stalled replication forks

scientific article published on 01 May 2012

Dimerization of Sir3 via its C-terminal winged helix domain is essential for yeast heterochromatin formation

scientific article

Disease-associated DNA2 nuclease-helicase protects cells from lethal chromosome under-replication

scientific article published on 16 June 2020

Distinct roles for SWR1 and INO80 chromatin remodeling complexes at chromosomal double-strand breaks.

scientific article

Distortion of the DNA double helix by RAP1 at silencers and multiple telomeric binding sites.

scientific article

Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms.

scientific article published on 3 February 2011

Early initiation of a replication origin tethered at the nuclear periphery

scientific article

Ectopic expression of human topoisomerase IIalpha fragments and etoposide resistance in mammalian cells.

scientific article published on October 2000

Epigenetics and disease: pharmaceutical opportunities. Preface

scientific article published on 01 January 2011

Epigenetics in Saccharomyces cerevisiae

scientific article

Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression

scientific article published on 01 July 1996

From snapshots to moving pictures: new perspectives on nuclear organization.

scientific article

Functional interaction between the estrogen receptor and CTF1: analysis of the vitellogenin gene B1 promoter in yeast.

scientific article published on October 1998

Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase

scientific article

Gene regulation through nuclear organization.

scientific article published on 5 November 2007

Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways

scientific article published on 07 January 2019

H3K9me selectively blocks transcription factor activity and ensures differentiated tissue integrity

scientific article published on 04 November 2021

Heterochromatic foci and transcriptional repression by an unstructured MET-2/SETDB1 co-factor LIN-65

scientific article published on 08 February 2019

Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells

scientific article

Heterochromatin protein 1: don't judge the book by its cover!

scientific article

Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast

scientific article (publication date: 24 February 1995)

Histone H3K9 methylation is dispensable for Caenorhabditis elegans development but suppresses RNA:DNA hybrid-associated repeat instability

scientific article published on 26 September 2016

Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates.

scientific article published on 9 January 2017

Histones and histone modifications in perinuclear chromatin anchoring: from yeast to man

scientific article

INO80 and SWR complexes: relating structure to function in chromatin remodeling

scientific article published on 31 July 2014

INO80-C and SWR-C: guardians of the genome

scientific article

Identification and purification of a protein that binds the yeast ARS consensus sequence.

scientific article

Imaging the asymmetrical DNA bend induced by repressor activator protein 1 with scanning tunneling microscopy

scientific article published on 01 July 1994

Import of proteins into mitochondria. Energy-dependent uptake of precursors by isolated mitochondria

scientific article published on 01 November 1982

Import of proteins into mitochondria. Energy-dependent, two-step processing of the intermembrane space enzyme cytochrome b2 by isolated yeast mitochondria

scientific article published on 01 November 1982

Import of proteins into mitochondria. In vitro studies on the biogenesis of the outer membrane

scientific article published on 01 March 1983

Imported mitochondrial proteins cytochrome b2 and cytochrome c1 are processed in two steps

scientific article

In Vitro DNA Replication in Yeast Nuclear Extracts

scientific article published on 01 July 1999

In vitro DNA replication assays in yeast extracts

scientific article

Increased mobility of double-strand breaks requires Mec1, Rad9 and the homologous recombination machinery

scientific article published on 8 April 2012

Indirect reduction and tension-band plating of tibial non-union with deformity ⬇️

scientific article published on October 1, 1992

Ino80 chromatin remodeling complex promotes recovery of stalled replication forks

scientific article published on 10 April 2008

Intracellular trafficking of yeast telomerase components.

scientific article

Ku-deficient yeast strains exhibit alternative states of silencing competence

scientific article

LSM2-8 and XRN-2 contribute to the silencing of H3K27me3-marked genes through targeted RNA decay

scientific article published on 06 April 2020

Leap year: Rare day to highlight rare diseases

journal article; published in Nature on 2012-01-18

LifeTime and improving European healthcare through cell-based interceptive medicine

scientific article published on 07 September 2020

Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast

scientific article published on 01 December 2002

Localization of RAP1 and topoisomerase II in nuclei and meiotic chromosomes of yeast ⬇️

scientific article published on June 1, 1992

Locking the genome: nuclear organization and cell fate

scientific article

Long-range compaction and flexibility of interphase chromatin in budding yeast analyzed by high-resolution imaging techniques.

scholarly article

Loss of an H3K9me anchor rescues laminopathy-linked changes in nuclear organization and muscle function in an Emery-Dreifuss muscular dystrophy model

scientific article published on 05 March 2020

Lte1, Cdc14 and MEN-controlled Cdk inactivation in yeast coordinate rDNA decompaction with late telophase progression.

scientific article

MAP kinase signaling induces nuclear reorganization in budding yeast.

scientific article published on April 2000

Measuring limits of telomere movement on nuclear envelope

scientific article

Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress

scientific article published on 21 January 2016

Mechanism of chromatin segregation to the nuclear periphery in C. elegans embryos.

scientific article published on 31 May 2016

Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance.

scientific article

Meiosis-specific prophase-like pathway controls cleavage-independent release of cohesin by Wapl phosphorylation

scientific article published on 03 January 2019

Meiotic behaviours of chromosomes and microtubules in budding yeast: relocalization of centromeres and telomeres during meiotic prophase.

scientific article published in September 1998

Metaphase chromosome structure. Involvement of topoisomerase II

scientific article published on 01 April 1986

Methods for visualizing chromatin dynamics in living yeast.

scientific article published in January 2004

Mitotic expression of Spo13 alters M-phase progression and nucleolar localization of Cdc14 in budding yeast

scientific article

Modulation of drug sensitivity in yeast cells by the ATP-binding domain of human DNA topoisomerase IIalpha

scientific article

Multiple pathways for telomere tethering: functional implications of subnuclear position for heterochromatin formation.

scientific article published on March 2004

Multiple pathways tether telomeres and silent chromatin at the nuclear periphery: functional implications for sir-mediated repression.

scientific article

Mutations in the C-terminal domain of topoisomerase II affect meiotic function and interaction with the casein kinase 2 beta subunit

scientific article published on 01 January 1999

Myosin-like proteins 1 and 2 are not required for silencing or telomere anchoring, but act in the Tel1 pathway of telomere length control.

scientific article published in October 2002

New systems for replicating DNA in vitro ⬇️

scientific article published on 01 June 1998

Nuclear Actin and Actin-Binding Proteins in DNA Repair

scientific article published on 04 April 2019

Nuclear Architecture: Past and Future Tense

scientific article published on 10 May 2016

Nuclear compartments and gene regulation.

scientific article

Nuclear geometry and rapid mitosis ensure asymmetric episome segregation in yeast.

scientific article published on 30 December 2010

Nuclear organization and silencing: putting things in their place

scientific article published on 01 March 2002

Nuclear organization and silencing: trafficking of Sir proteins

scientific article published on 01 January 1998

Nuclear organization and transcriptional silencing in yeast.

scientific article

Nuclear organization in DNA end processing: Telomeres vs double-strand breaks.

scientific article published on May 2015

Nuclear organization in genome stability: SUMO connections

scientific article

Nuclear pore association confers optimal expression levels for an inducible yeast gene

scientific article published in Nature

Nucleosome remodelers in double-strand break repair.

scientific article published on 23 January 2013

Nucleus and gene expression

Nucleus and gene expression

Nutrition and the biology of human ageing: molecular mechanisms underlying ageing

scientific article published on 01 January 2013

ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase

scientific article published on December 2002

ORC-dependent and origin-specific initiation of DNA replication at defined foci in isolated yeast nuclei

scientific article published on 01 June 1997

On TADs and LADs: Spatial Control Over Gene Expression.

scientific article

Once and Only Once

scientific article published on 02 April 2019

Open questions: epigenetics and the role of heterochromatin in development

scientific article

Perinuclear Anchoring of H3K9-Methylated Chromatin Stabilizes Induced Cell Fate in C. elegans Embryos.

scientific article published on 18 November 2015

Phosphorylation of the C-terminal domain of yeast topoisomerase II by casein kinase II affects DNA-protein interaction

scientific article published on 01 October 1994

PolySUMOylation by Siz2 and Mms21 triggers relocation of DNA breaks to nuclear pores through the Slx5/Slx8 STUbL.

scientific article

Positions of potential: nuclear organization and gene expression.

scientific article

Posttranslational modifications of repair factors and histones in the cellular response to stalled replication forks.

scientific article published on 30 May 2009

Preparation and characterization of yeast nuclear extracts for efficient RNA polymerase B (II)-dependent transcription in vitro.

scientific article published in December 1990

Promoter- and RNA polymerase II-dependent hsp-16 gene association with nuclear pores in Caenorhabditis elegans

scientific article

Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine

scientific article published on 17 March 2021

RAP-1 factor is necessary for DNA loop formation in vitro at the silent mating type locus HML

scientific article published on 01 June 1989

RAP1 stimulates single- to double-strand association of yeast telomeric DNA: implications for telomere-telomere interactions

scientific article published in December 1994

RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together

scientific article

RecQ helicases and genome stability: lessons from model organisms and human disease.

scientific article published in August 2002

RecQ helicases: at the heart of genetic stability

scientific article

RecQ helicases: multiple roles in genome maintenance.

scientific article

Reconstitution of yeast silent chromatin: multiple contact sites and O-AADPR binding load SIR complexes onto nucleosomes in vitro

scientific article

Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair

scientific article (publication date: 17 December 2004)

Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae.

scientific article

Redundancy, insult-specific sensors and thresholds: unlocking the S-phase checkpoint response

scientific article published on June 2004

Regulating repression: roles for the sir4 N-terminus in linker DNA protection and stabilization of epigenetic states

scientific article

Regulation of nuclear positioning and dynamics of the silent mating type loci by the yeast Ku70/Ku80 complex

scientific article published on December 2008

Regulation of recombination at yeast nuclear pores controls repair and triplet repeat stability.

scientific article published on 4 May 2015

Regulation of topoisomerase II by phosphorylation: a role for casein kinase II.

scientific article published on February 1993

Remodelers move chromatin in response to DNA damage.

scientific article published on 14 February 2014

Repairing subtelomeric DSBs at the nuclear periphery.

scientific article

Repeat DNA in genome organization and stability.

scientific article published on 24 April 2015

Repetitive Transgenes in C. elegans Accumulate Heterochromatic Marks and Are Sequestered at the Nuclear Envelope in a Copy-Number- and Lamin-Dependent Manner

scientific article published on 01 January 2010

Replication checkpoint: tuning and coordination of replication forks in s phase

scientific article published on 19 August 2013

Replication foci dynamics: replication patterns are modulated by S-phase checkpoint kinases in fission yeast.

scientific article

Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations

scientific article published in December 2005

Repressive Chromatin in Caenorhabditis elegans: Establishment, Composition, and Function

scientific article

Ribonuclease H(70) is a component of the yeast nuclear scaffold

scientific article published on 01 July 1990

Ribosome biogenesis factors bind a nuclear envelope SUN domain protein to cluster yeast telomeres

scientific article

Roles for nuclear organization in the maintenance of genome stability

scientific article published on April 2010

SIR proteins and the assembly of silent chromatin in budding yeast

scientific article

SIR-nucleosome interactions: structure-function relationships in yeast silent chromatin.

scientific article published on 18 June 2013

SUMO wrestles breaks to the nuclear ring's edge.

scientific article published on 2 August 2016

SWR1 and INO80 chromatin remodelers contribute to DNA double-strand break perinuclear anchorage site choice.

scientific article published on 24 July 2014

Selfish DNA and Epigenetic Repression Revisited.

scientific article published on November 2016

Semi-conservative replication in yeast nuclear extracts requires Dna2 helicase and supercoiled template.

scientific article

Separation of silencing from perinuclear anchoring functions in yeast Ku80, Sir4 and Esc1 proteins.

scientific article published on 11 March 2004

Sif2p interacts with Sir4p amino-terminal domain and antagonizes telomeric silencing in yeast.

scientific article

Silent chromatin at the middle and ends: lessons from yeasts

scientific article published on 23 July 2009

Sir-mediated repression can occur independently of chromosomal and subnuclear contexts

scientific article published on 01 December 2004

Spatial segregation of heterochromatin: Uncovering functionality in a multicellular organism.

scientific article published on 17 May 2016

Srs2 helicase prevents the formation of toxic DNA damage during late prophase I of yeast meiosis

scientific article published on 06 June 2019

Srs2 helicase prevents the formation of toxic DNA damage during late prophase I of yeast meiosis: Supplemental Fig 1-5 and Table 1

article

Step-wise methylation of histone H3K9 positions heterochromatin at the nuclear periphery.

scientific article published in August 2012

Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage

scientific article published on 11 October 2017

Structural Maintenance of Chromosomes Protein C-terminal Domains Bind Preferentially to DNA with Secondary Structure ⬇️

scientific article published on September 11, 1998

Structural basis for the role of the Sir3 AAA+ domain in silencing: interaction with Sir4 and unmethylated histone H3K79

scientific article

Structure and function in the budding yeast nucleus.

scientific article

Subtelomeric factors antagonize telomere anchoring and Tel1-independent telomere length regulation

scientific article

Sucrose gradient chromatin enrichment for quantitative proteomics analysis in budding yeast

scientific article published on 14 September 2021

Susan Gasser. Interview.

scientific article published in October 2005

Synergistic lethality between BRCA1 and H3K9me2 loss reflects satellite derepression

scientific article published on 25 February 2019

TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks.

scientific article

TORC2-a new player in genome stability

scientific article

Targeted INO80 enhances subnuclear chromatin movement and ectopic homologous recombination

scientific article published on February 2012

Targeting Sir proteins to sites of action: a general mechanism for regulated repression.

scientific article

Telomere maintenance and gene repression: a common end?

scientific article published on June 1994

Telomeres and telomerase

scientific article published on 01 September 1999

Temporal separation of replication and recombination requires the intra-S checkpoint.

scientific article

The Dynamics of Yeast Telomeres and Silencing Proteins through the Cell Cycle

article

The INO80 remodeller in transcription, replication and repair

scientific article published in October 2017

The Importance of Satellite Sequence Repression for Genome Stability.

scientific article published on 13 November 2017

The MRX Complex Ensures NHEJ Fidelity through Multiple Pathways Including Xrs2-FHA-Dependent Tel1 Activation

scientific article

The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast.

scientific article

The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin

scientific article published on 12 September 2019

The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin

scientific article published on 01 January 2020

The budding yeast nucleus.

scientific article

The carboxy termini of Sir4 and Rap1 affect Sir3 localization: evidence for a multicomponent complex required for yeast telomeric silencing

scientific article

The composition and morphology of yeast nuclear scaffolds.

scientific article

The cytochrome b5 tail anchors and stabilizes subdomains of human DNA topoisomerase II alpha in the cytoplasm of retrovirally infected mammalian cells.

scientific article published on June 1999

The formation and sequestration of heterochromatin during development: delivered on 7 September 2012 at the 37th FEBS Congress in Sevilla, Spain.

scientific article published on 3 June 2013

The function of nuclear architecture: a genetic approach

scientific article

The function of telomere clustering in yeast: the circe effect.

scientific article

The functional importance of telomere clustering: global changes in gene expression result from SIR factor dispersion

scientific article published on 29 January 2009

The genetics of epigenetics.

scientific article published on January 1998

The histone code at DNA breaks: a guide to repair?

scientific article

The molecular biology of the SIR proteins ⬇️

scientific article published on November 14, 2001

The nuclear envelope and transcriptional control.

scientific article published on 5 June 2007

The nuclear envelope--a scaffold for silencing?

scientific article published on 19 March 2009

The organisation of chromatin loops: characterization of a scaffold attachment site.

scientific article

The origin recognition complex functions in sister-chromatid cohesion in Saccharomyces cerevisiae.

scientific article

The positioning and dynamics of origins of replication in the budding yeast nucleus.

scientific article

The positioning of yeast telomeres depends on SIR3, SIR4, and the integrity of the nuclear membrane

scientific article published on 01 January 1993

The processing of double-strand breaks and binding of single-strand-binding proteins RPA and Rad51 modulate the formation of ATR-kinase foci in yeast

scientific article

The regulation of DNA topoisomerase II by casein kinase II

scientific article published on 01 January 1994

The regulation of euchromatin and heterochromatin by histones in yeast.

scientific article published on January 1995

The shelterin protein POT-1 anchors Caenorhabditis elegans telomeres through SUN-1 at the nuclear periphery

scientific article published on 02 December 2013

The spatial dynamics of tissue-specific promoters during C. elegans development

scientific article published on April 2010

The study of protein recruitment to laser-induced DNA lesions can be distorted by photoconversion of the DNA binding dye Hoechst

scientific article published on 25 January 2019

Topoisomerase II: its functions and phosphorylation

scientific article published on August 1, 1992

Ultrastructural cryoimmunocytochemistry is a convenient tool for the study of DNA replication in cultured cells

scientific article published on 01 June 1991

Visualization of Chromatin Decompaction and Break Site Extrusion as Predicted by Statistical Polymer Modeling of Single-Locus Trajectories.

scientific article published in January 2017

Visualizing chromatin dynamics in interphase nuclei.

scientific article

Visualizing the spatiotemporal dynamics of DNA damage in budding yeast

scientific article published on 01 January 2015

Visualizing yeast chromosomes and nuclear architecture

scientific article published on 01 March 2010

Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling.

scientific article

Yeast telomerase and the SUN domain protein Mps3 anchor telomeres and repress subtelomeric recombination

scientific article published on April 2009

[Telomere-binding activity of Schizosaccharomyces pombe yeasts]

scientific article published on 01 July 1999

γH2A is a component of yeast heterochromatin required for telomere elongation.

scientific article published on 15 January 2011

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