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List of works by Konrad Basler

A Comprehensive Drosophila melanogaster Transcription Factor Interactome

scientific article published on 01 April 2019

A RING finger to wed TCF and β-catenin.

scientific article published on 12 March 2013

A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion

scientific article

A cytoplasmic role of Wnt/β-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation.

scientific article

A genome-wide RNA interference screen uncovers two p24 proteins as regulators of Wingless secretion. ⬇️

scientific article published on 28 October 2011

A high-throughput template for optimizingDrosophilaorgan culture with response-surface methods ⬇️

scientific article published on February 1, 2013

A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development

scientific article

A non-redundant role for Drosophila Mkk4 and hemipterous/Mkk7 in TAK1-mediated activation of JNK

scientific article

A novel role for the tumour suppressor Nitrilase1 modulating the Wnt/β-catenin signalling pathway

scientific article published on 5 January 2016

A regulatory receptor network directs the range and output of the Wingless signal

scientific article published in June 2014

A simple molecular complex mediates widespread BMP-induced repression during Drosophila development.

scientific article published on August 2004

A transcriptomics resource reveals a transcriptional transition during ordered sarcomere morphogenesis in flight muscle.

scientific article published on 30 May 2018

A versatile platform for creating a comprehensive UAS-ORFeome library in Drosophila ⬇️

scientific article published on May 1, 2013

An ancient defense system eliminates unfit cells from developing tissues during cell competition

scientific article published on December 2014

Antagonistic growth regulation by Dpp and Fat drives uniform cell proliferation.

scientific article published in January 2011

BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling

scientific article

Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas

scientific journal article

CRISPR-induced double-strand breaks trigger recombination between homologous chromosome arms

scientific article published on 13 June 2019

Canonical wnt signaling regulates atrioventricular junction programming and electrophysiological properties.

scientific article

Cell biology. Cytonemes show their colors.

scientific article published in April 2011

Cell-sorting at the A/P boundary in the Drosophila wing primordium: a computational model to consolidate observed non-local effects of Hh signaling

scientific article

Cells compete for decapentaplegic survival factor to prevent apoptosis in Drosophila wing development.

scientific article published in April 2002

Challenging FRET-based E-Cadherin force measurements in Drosophila.

scientific article

Combining Time-of-Flight Secondary Ion Mass Spectrometry Imaging Mass Spectrometry and CARS Microspectroscopy Reveals Lipid Patterns Reminiscent of Gene Expression Patterns in the Wing Imaginal Disc of Drosophila melanogaster.

scientific article

Confronting morphogen gradients: how important are they for growth?

scientific article published on 27 October 2009

Coop functions as a corepressor of Pangolin and antagonizes Wingless signaling

scientific article

Coordination of patterning and growth by the morphogen DPP.

scientific article published on March 2014

Cryo-EM structure of the Hedgehog release protein Dispatched

scientific article published on 15 April 2020

Cultivation and Live Imaging of Drosophila Imaginal Discs.

scientific article published in January 2016

DIGESTIF: a universal quality standard for the control of bottom-up proteomics experiments.

scientific article published on 30 December 2014

Deterministic protein inference for shotgun proteomics data provides new insights into Arabidopsis pollen development and function.

scientific article

Differential regulation of β-catenin-mediated transcription via N- and C-terminal co-factors governs identity of murine intestinal epithelial stem cells

scientific article published on 01 March 2021

Distinct adhesion-independent functions of β-catenin control stage-specific sensory neurogenesis and proliferation

scientific article published on 11 April 2015

Distinct populations of crypt-associated fibroblasts act as signaling hubs to control colon homeostasis

scientific article published on 11 December 2020

Dpp controls growth and patterning in Drosophila wing precursors through distinct modes of action.

scientific article published on 4 July 2017

Drosophila DDX3/Belle Exerts Its Function Outside of the Wnt/Wingless Signaling Pathway ⬇️

scientific article

Drosophila ciD encodes a hybrid Pangolin/Cubitus interruptus protein that diverts the Wingless into the Hedgehog signaling pathway.

scientific article published in November 1998

Drosophila wing imaginal discs respond to mechanical injury via slow InsP3R-mediated intercellular calcium waves.

scientific article

EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation

scientific article published on 28 June 2018

EpiTools: An Open-Source Image Analysis Toolkit for Quantifying Epithelial Growth Dynamics

scientific article

Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily

scientific article published in July 2002

Exploring the effects of mechanical feedback on epithelial topology.

scientific article published in February 2010

Forces controlling organ growth and size

scientific article published on 29 November 2016

Functional Characterization of Drosophila microRNAs by a Novel in Vivo Library ⬇️

scientific article published on October 10, 2012

GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells

scientific article published in Nature

Generating and navigating proteome maps using mass spectrometry.

scientific article published on 14 October 2010

Generation of a transgenic ORFeome library in Drosophila.

scientific article

Generation of a versatile BiFC ORFeome library for analyzing protein-protein interactions in live

scientific article published on 24 September 2018

Generation of genome-modified Drosophila cell lines using SwAP.

scientific article

Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched

scientific journal article

Identification and in vivo role of the Armadillo-Legless interaction.

scientific article

Identification of an endocytosis motif in an intracellular loop of Wntless protein, essential for its recycling and the control of Wnt protein signaling

scientific article published on 25 October 2011

Improved prediction of peptide detectability for targeted proteomics using a rank-based algorithm and organism-specific data

scientific article

Integrating force-sensing and signaling pathways in a model for the regulation of wing imaginal disc size.

scientific article

Large-scale imaginal disc sorting: A protocol for "omics"-approaches.

scientific article published on 13 April 2014

Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation

scientific article published on 30 November 2015

Loss of PI3K blocks cell-cycle progression in a Drosophila tumor model.

scientific article published on 25 April 2011

Manipulating the sensitivity of signal-induced repression: quantification and consequences of altered brinker gradients.

scientific article

MorphoGraphX: A platform for quantifying morphogenesis in 4D

scientific article published on 6 May 2015

Morphogen gradients: expand and repress.

scientific article published in October 2011

Multiorder correction algorithms to remove image distortions from mass spectrometry imaging data sets.

scientific article

Mutations in and genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling

article

Myocardial β-Catenin-BMP2 signaling promotes mesenchymal cell proliferation during endocardial cushion formation

scientific article published on 08 September 2018

Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development

scientific article

Pharmacological interventions in the Wnt pathway: inhibition of Wnt secretion versus disrupting the protein-protein interfaces of nuclear factors

scientific article

Pharmacophore-guided discovery of CDC25 inhibitors causing cell cycle arrest and tumor regression

scientific article published in Scientific Reports

Porcupine-mediated lipidation is required for Wnt recognition by Wls.

scientific article

Powerful Drosophila screens that paved the wingless pathway.

scientific article

Probing the canonicity of the Wnt/Wingless signaling pathway

scientific article

Protection of armadillo/β-Catenin by armless, a novel positive regulator of wingless signaling

scientific article (publication date: November 2014)

Quantitative proteomics: a central technology for systems biology

scientific article published on 21 December 2009

Reactivation of a developmental signaling center is required for therapeutic control of the murine periosteal niche

scientific article published on 08 February 2019

Reflections on cell competition

scientific article published on 05 May 2014

Signal-induced repression: the exception or the rule in developmental signaling?

scientific article published on July 2008

Specification of cell fate in the developing eye ofDrosophila ⬇️

scientific article published on December 1, 1991

Sphingolipid depletion impairs endocytic traffic and inhibits Wingless signaling.

scientific article published on 9 May 2013

Structure-function analysis of Eiger, the Drosophila TNF homolog.

scientific article published in March 2009

TCF/LEF dependent and independent transcriptional regulation of Wnt/β-catenin target genes

scientific article published on 13 November 2018

The Decapentaplegic morphogen gradient: from pattern formation to growth regulation

scientific article (publication date: September 2007)

The Drosophila TNF receptor Grindelwald couples loss of cell polarity and neoplastic growth.

scientific article

The PHD domain is required to link Drosophila Pygopus to Legless/beta-catenin and not to histone H3.

scientific article

The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription

scientific journal article

The Toll pathway inhibits tissue growth and regulates cell fitness in an infection-dependent manner

scientific article published on 19 November 2018

The hedgehog signaling pathway: where did it come from?

scientific article

The many faces and functions of β-catenin

scientific article

The paired box gene pox neuro: a determinant of poly-innervated sense organs in Drosophila

scientific article published on April 3, 1992

The role of Parafibromin/Hyrax as a nuclear Gli/Ci-interacting protein in Hedgehog target gene control.

scientific article published on 11 February 2009

The transcription factor Ets21C drives tumor growth by cooperating with AP-1.

scientific article published on 07 October 2016

Transcription in the absence of histone H3.2 and H3K4 methylation.

scientific article published on 8 November 2012

Transcription in the absence of histone H3.3.

scientific article

Transcription under the control of nuclear Arm/beta-catenin.

scientific article

Transforming growth factor-β-dependent Wnt secretion controls myofibroblast formation and myocardial fibrosis progression in experimental autoimmune myocarditis.

scientific article published on 20 April 2016

WNT ligands control initiation and progression of human papillomavirus-driven squamous cell carcinoma.

scientific article published on 17 April 2018

WNT secretion and signalling in human disease.

scientific article published on 14 July 2012

Wnt Ligands as a Part of the Stem Cell Niche in the Intestine and the Liver.

scientific article published on 8 January 2018

Wnt signalling requires MTM-6 and MTM-9 myotubularin lipid-phosphatase function in Wnt-producing cells.

scientific article

Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex

scientific article

Wnt/β-catenin signaling regulates sequential fate decisions of murine cortical precursor cells

scientific article published in January 2015

Xrp1 is a transcription factor required for cell competition-driven elimination of loser cells

scientific article published in Scientific Reports

Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation

scientific article published on 01 April 2019

Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner

article

dMyc transforms cells into super-competitors

scientific article published in April 2004

β-Catenin C-terminal signals suppress p53 and are essential for artery formation

scientific article published on 08 August 2016

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