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List of works by Euan A. Ashley

A Balanced Look at the Implications of Genomic (and Other "Omics") Testing for Disease Diagnosis and Clinical Care

scientific article

A New Approach to Rare Diseases of Children: The Undiagnosed Diseases Network

scientific article published on 11 January 2018

A Patient with Sjogren's Syndrome and Subsequent Diagnosis of Inclusion Body Myositis and Light-Chain Amyloidosis

scientific article published on 18 March 2019

A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay

scientific article published on 01 February 2019

A Rapid, High-Quality, Cost-Effective, Comprehensive and Expandable Targeted Next-Generation Sequencing Assay for Inherited Heart Diseases.

scientific article

A Reference Equation for Normal Standards for VO2 Max: Analysis from the Fitness Registry and the Importance of Exercise National Database (FRIEND Registry).

scientific article published on April 2017

A clinical approach to inherited hypertrophy: the use of family history in diagnosis, risk assessment, and management.

scientific article published on February 2013

A comparison of methods for determining the ventilatory threshold: implications for surgical risk stratification

scientific article published on 05 April 2017

A general framework for dose optimization.

scientific article published on 14 November 2009

A long noncoding RNA protects the heart from pathological hypertrophy

scientific article

A meta-analysis of the prognostic significance of cardiopulmonary exercise testing in patients with heart failure

scientific article published on January 2013

A method for determining exercise oscillatory ventilation in heart failure: Prognostic value and practical implications

scientific article

A neural network approach to predicting outcomes in heart failure using cardiopulmonary exercise testing

scientific article

A new era in clinical genetic testing for hypertrophic cardiomyopathy

scientific article published on 30 October 2009

A novel noninvasive method for remote heart failure monitoring: the EuleriAn video Magnification apPLications In heart Failure studY (AMPLIFY)

scientific article published on 21 August 2019

A public resource facilitating clinical use of genomes

scientific article (publication date: 24 July 2012)

A reference equation for maximal aerobic power for treadmill and cycle ergometer exercise testing: Analysis from the FRIEND registry.

scientific article published in January 2018

A research roadmap for next-generation sequencing informatics

scientific article published on April 2016

A resource of lipidomics and metabolomics data from individuals with undiagnosed diseases

scientific article published on 21 April 2021

A toolkit for genetics providers in follow-up of patients with non-diagnostic exome sequencing

article

APJ acts as a dual receptor in cardiac hypertrophy ⬇️

scientific article published on August 16, 2012

APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer’s disease pathology

scholarly article

Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells

scientific article

Abnormal electrocardiographic findings in athletes: recognising changes suggestive of cardiomyopathy.

scientific article published on February 2013

Abnormal electrocardiographic findings in athletes: recognising changes suggestive of primary electrical disease.

scientific article published on February 2013

Accuracy in Wrist-Worn, Sensor-Based Measurements of Heart Rate and Energy Expenditure in a Diverse Cohort

scientific article

Accuracy of Smartphone Camera Applications for Detecting Atrial Fibrillation: A Systematic Review and Meta-analysis

scientific article published on 01 April 2020

Acetaminophen or Tylenol? A Retrospective Analysis of Medication Digital Communication Practices

scientific article published on 01 August 2018

Achieving high-sensitivity for clinical applications using augmented exome sequencing

scientific article

Adding an electrocardiogram to the pre-participation examination in competitive athletes: a systematic review

scientific article published on December 2009

Addition of the electrocardiogram to the preparticipation examination of college athletes

scientific article

Additive prognostic value of a cardiopulmonary exercise test score in patients with heart failure and intermediate risk

article published in 2015

Age and double product (systolic blood pressure x heart rate) reserve-adjusted modification of the Duke Treadmill Score nomogram in men.

scientific article published on 11 September 2008

Allele-Specific Silencing Ameliorates Restrictive Cardiomyopathy Attributable to a Human Myosin Regulatory Light Chain Mutation

scientific article published on 18 July 2019

Alterations in Cardiac Mechanics Following Ultra-Endurance Exercise: Insights from Left and Right Ventricular Area-Deformation Loops

scientific article published on 30 June 2016

Angiotensin-converting enzyme genotype predicts cardiac and autonomic responses to prolonged exercise

scientific article published on 12 July 2006

Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition

scientific article published on 18 May 2018

Apelin enhances directed cardiac differentiation of mouse and human embryonic stem cells

scientific article

Apelin increases atrial conduction velocity, refractoriness, and prevents inducibility of atrial fibrillation

scientific article published on 03 September 2020

Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation

scientific article

Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis

scientific article

Applying current normative data to prognosis in heart failure: The Fitness Registry and the Importance of Exercise National Database (FRIEND).

scientific article published on 27 February 2018

Approaching Higher Dimension Imaging Data Using Cluster-Based Hierarchical Modeling in Patients with Heart Failure Preserved Ejection Fraction

scientific article published on 18 July 2019

Arrhythmogenic Right Ventricular Cardiomyopathy: Toward a Modern Clinical and Genomic Understanding

scientific article published on 01 June 2015

Artificial Intelligence in Cardiology

scientific article published on 01 June 2018

Association of Obesity With Adverse Long-term Outcomes in Hypertrophic Cardiomyopathy

scientific article published on 06 November 2019

Association of Race With Disease Expression and Clinical Outcomes Among Patients With Hypertrophic Cardiomyopathy

scientific article published on 04 December 2019

Associations Between Female Sex, Sarcomere Variants and Clinical Outcomes in Hypertrophic Cardiomyopathy

scientific article published on 07 December 2020

Athletic Remodeling in Female College Athletes, the "Morganroth Hypothesis" Revisited

scientific article published on 23 January 2018

Athlome Project Consortium: a concerted effort to discover genomic and other "omic" markers of athletic performance

scientific article published on 29 December 2015

BMP promotes motility and represses growth of smooth muscle cells by activation of tandem Wnt pathways ⬇️

scientific article

Better decisions through science: exercise testing scores

scientific article

Biallelic Mutations in ATP5F1D, which Encodes a Subunit of ATP Synthase, Cause a Metabolic Disorder

scientific article published on 16 February 2018

Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank.

scientific article

Blood pressure in athletic preparticipation evaluation and the implication for cardiac remodelling

scientific article published on 28 May 2019

Broad Genetic Testing in a Clinical Setting Uncovers a High Prevalence of Titin Loss-of-Function Variants in Very Early Onset Atrial Fibrillation

scientific article published on 22 October 2019

COMPARISON OF UNITED STATES AND EUROPEAN CRITERIA FOR HYPERTENSION IN A LARGE COHORT OF COMPETITIVE ATHLETES EXAMINED AS PART OF PRE-PARTICIPATION EVALUATION

scholarly article

CORRELATION OF ECHOCARDIOGRAPHIC FINDINGS WITH SYMPTOMS IN HYPERTROPHIC CARDIOMYOPATHY PATIENTS

scholarly article

Cardiac Imaging of Aortic Valve Area from 34,287 UK Biobank Participants Reveal Novel Genetic Associations and Shared Genetic Comorbidity with Multiple Disease Phenotypes

scientific article published on 30 October 2020

Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling

scientific article published on 6 March 2003

Cardiac nitric oxide synthase 1 regulates basal and beta-adrenergic contractility in murine ventricular myocytes

scientific article

Cardiac structural and sarcomere genes associated with cardiomyopathy exhibit marked intolerance of genetic variation.

scientific article

Cardiology Explained ⬇️

scientific book published on September 8, 2010

Cardiopulmonary Exercise Testing, Impedance Cardiography, and Reclassification of Risk in Patients Referred for Heart Failure Evaluation

scientific article published on 24 August 2019

Cardiopulmonary and noninvasive hemodynamic responses to exercise predict outcomes in heart failure

scientific article published in February 2013

Cardiopulmonary responses and prognosis in hypertrophic cardiomyopathy: a potential role for comprehensive noninvasive hemodynamic assessment.

scientific article published on 8 April 2015

Cardiovascular Precision Medicine in the Genomics Era

scientific article published on 01 April 2018

Cardiovascular disease: The rise of the genetic risk score.

scientific article

Care in Specialized Centers and Data Sharing Increase Agreement in Hypertrophic Cardiomyopathy Genetic Test Interpretation

scientific article published on October 2017

Causative Variants for Inherited Cardiac Conditions in a Southeast Asian Population Cohort

scientific article published on 07 February 2022

Cell-Intrinsic Functional Effects of the α-Cardiac Myosin Arg-403-Gln Mutation in Familial Hypertrophic Cardiomyopathy ⬇️

scientific article published on June 19, 2012

Challenges in the clinical application of whole-genome sequencing

scientific article published on 29 April 2010

Chromatin regulation by Brg1 underlies heart muscle development and disease

scientific article

Classifying Drugs by their Arrhythmogenic Risk Using Machine Learning

scientific article published on 22 January 2020

Clinical assessment incorporating a personal genome

scientific article

Clinical characteristics and outcomes in childhood-onset hypertrophic cardiomyopathy

scientific article published on 26 March 2021

Clinical interpretation and implications of whole-genome sequencing

scientific article published in March 2014

Clinical phenotype and outcome of hypertrophic cardiomyopathy associated with thin-filament gene mutations

scientific article

Comparison of QT Interval Measurement Methods and Correction Formulas in Atrial Fibrillation

scientific article published on 13 March 2019

Comparison of left ventricular manual versus automated derived longitudinal strain: implications for clinical practice and research

scientific article published on 17 November 2015

Computational prediction of protein subdomain stability in MYBPC3 enables clinical risk stratification in hypertrophic cardiomyopathy and enhances variant interpretation

scientific article published in July 2021

Computerized Q wave dimensions in athletes and hypertrophic cardiomyopathy patients

scientific article published on 14 February 2015

Contractile reserve and cardiopulmonary exercise parameters in patients with dilated cardiomyopathy, the two dimensions of exercise testing

scientific article published on 6 July 2017

Cost-effectiveness of preparticipation screening for prevention of sudden cardiac death in young athletes

scientific article

DNA sequencing: clinical applications of new DNA sequencing technologies.

scientific article

De Novo and Rare Variants at Multiple Loci Support the Oligogenic Origins of Atrioventricular Septal Heart Defects.

scientific article

Deep Learning Automates the Quantitative Analysis of Individual Cells in Live-Cell Imaging Experiments

scientific article

Deep learning interpretation of echocardiograms

scientific article published on 24 January 2020

Defining genotype-phenotype relationships in patients with hypertrophic cardiomyopathy using cardiovascular magnetic resonance imaging.

scientific article

Defining the limits of athlete's heart: implications for screening in diverse populations

scientific article published on 22 February 2010

Delivering Clinical Grade Sequencing and Genetic Test Interpretation for Cardiovascular Medicine

scientific article published on 01 April 2017

Denoising of Quality Scores for Boosted Inference and Reduced Storage

scientific article published in March 2016

Designing clinically translatable artificial intelligence systems for high-dimensional medical imaging

scientific article published in 2021

Diagnosing coronary artery disease in diabetic patients

scientific article

Differential Response Trajectories to Acute Exercise in Blood and Muscle ⬇️

scholarly article

Digital Health Applications for Pharmacogenetic Clinical Trials

scientific article published on 26 October 2020

Digital Randomized Controlled Trial of Physical Activity Interventions (A Substudy of the MyHeart Counts Cardiovascular Health Study)

scientific article published on 24 March 2020

Direct-to-consumer genetic testing for predicting sports performance and talent identification: Consensus statement

scientific article

Disease-specific variant pathogenicity prediction significantly improves variant interpretation in inherited cardiac conditions

scientific article published on 13 October 2020

Does size matter? Clinical applications of scaling cardiac size and function for body size

scientific article published on April 2008

Drug Discovery in a Multidimensional World: Systems, Patterns, and Networks

Early Repolarization in an Ambulatory Clinical Population ⬇️

scientific article published on October 10, 2011

Early somatic mosaicism is a rare cause of long-QT syndrome

scientific article published on 28 September 2016

Echocardiographic Assessment of Left Ventricular Remodeling in American Style Footballers

scientific article published on 02 December 2019

Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease

Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease

Effect of Moderate-Intensity Exercise Training on Peak Oxygen Consumption in Patients With Hypertrophic Cardiomyopathy: A Randomized Clinical Trial

scientific article published on 17 March 2017

Effect of gender on computerized electrocardiogram measurements in college athletes

scientific article published in June 2010

Effect of lossy compression of quality scores on variant calling.

scientific article

Effects of respiratory exchange ratio on the prognostic value of peak oxygen consumption and ventilatory efficiency in patients with systolic heart failure

scientific article published on 11 September 2013

Electrocardiographic arrhythmia risk testing

scientific article published on July 2004

Electrocardiographic interpretation in athletes: the 'Seattle criteria'.

scientific article published on February 2013

Electrocardiographic predictors of atrial fibrillation

scientific article published on October 2009

Emerging role of the apelin system in cardiovascular homeostasis

scientific article published on 01 June 2007

Emerging therapies for the management of decompensated heart failure: from bench to bedside

scientific article published on 28 November 2006

Endogenous regulation of cardiovascular function by apelin-APJ.

scientific article published on 18 September 2009

Erratum: Corrigendum: Performance comparison of whole-genome sequencing platforms

scholarly article by Hugo Y K Lam et al published June 2012 in Nature Biotechnology

Establishing disease causality for a novel gene variant in familial dilated cardiomyopathy using a functional in-vitro assay of regulated thin filaments and human cardiac myosin.

scientific article published on 26 October 2015

European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) Expert Consensus Statement on the State of Genetic Testing for Cardiac Diseases

scientific article published in 2022

Exercise capacity and paroxysmal atrial fibrillation in patients with hypertrophic cardiomyopathy

scientific article published on 10 December 2013

Exercise oscillatory ventilation reflects diminished quality of life and perceived functional capacity in patients with heart failure

scientific article

Exercise testing scores as an example of better decisions through science

scientific article

Exome sequencing identifies de novo pathogenic variants in FBN1 and TRPS1 in a patient with a complex connective tissue phenotype.

scientific article published on January 2017

Exploratory insights from the right-sided electrocardiogram following prolonged endurance exercise.

scientific article

Extracutaneous manifestations in phacomatosis cesioflammea and cesiomarmorata: Case series and literature review

scientific article published on 28 March 2019

Extremely elevated lipoprotein(a), combined hyperlipidemia, and premature atherosclerosis in a Chinese family

scientific article published on 29 September 2010

Feasibility of Obtaining Measures of Lifestyle From a Smartphone App: The MyHeart Counts Cardiovascular Health Study

scientific article

Frontiers in nephrology: genomic approaches to understanding the molecular basis of atherosclerosis

scientific article published on 17 October 2007

Functional assessment and transplantation of the donor heart after circulatory death.

scientific article published on 16 July 2016

Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association

scientific article

Gender differences in ventricular remodeling and function in college athletes, insights from lean body mass scaling and deformation imaging.

scientific article

Gene coexpression network topology of cardiac development, hypertrophy, and failure

scientific article published on 2 December 2010

Genetic Reduction in Left Ventricular Protein Kinase C-α and Adverse Ventricular Remodeling in Human Subjects

Genetic analysis in cardiovascular disease: a clinical perspective

scientific article published on March 2011

Genetics and cardiovascular disease: a policy statement from the American Heart Association.

scientific article

Genetics of arrhythmia: disease pathways beyond ion channels

scientific article published on 15 May 2008

Genome Sequencing in Hypertrophic Cardiomyopathy

scientific article published on 01 July 2018

Genomics in clinical practice

scientific article published on October 2014

Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights from the Sarcomeric Human Cardiomyopathy Registry (SHaRe)

scientific article published on 23 August 2018

Graphical analysis for phenome-wide causal discovery in genotyped population-scale biobanks

scientific article published on 13 January 2021

HapIso: An Accurate Method for the Haplotype- Specific Isoforms Reconstruction From Long Single-Molecule Reads

scientific article

High-throughput SARS-CoV-2 and host genome sequencing from single nasopharyngeal swabs

scientific article published on 29 July 2020

How does morphology impact on diastolic function in hypertrophic cardiomyopathy? A single centre experience

scientific article

Human Genome Sequencing at the Population Scale: A Primer on High-Throughput DNA Sequencing and Analysis.

scientific article published in October 2017

Hypertrophic Cardiomyopathy as a Cause of Sudden Cardiac Death in the Young: A Meta-Analysis

scientific article

Hypertrophic Cardiomyopathy with Left Ventricular Systolic Dysfunction: Insights from the SHaRe Registry

scientific article published on 31 March 2020

Hypertrophic cardiomyopathy: can the horse be put back in the barn?

scientific article published in February 2015

INHERIT (INHibition of the renin angiotensin system in hypertrophic cardiomyopathy and the Effect on hypertrophy-a Randomised Intervention Trial with losartan)

scientific article

INTEGRATING CORRELATION BASED NETWORKS INTO RISK PROGNOSTICATION OF CARDIOMYOPATHY

scholarly article published in March 2018

Identification of a new target of miR-16, Vacuolar Protein Sorting 4a.

scientific article

Identification of rare-disease genes in diverse undiagnosed cases using whole blood transcriptome sequencing and large control cohorts

article

Identification of rare-disease genes using blood transcriptome sequencing and large control cohorts

scientific article published on 03 June 2019

Impact of Demographic Features, Lifestyle, and Comorbidities on the Clinical Expression of Hypertrophic Cardiomyopathy

scientific article published on 13 December 2017

Impact of Septal Reduction on Left Atrial Size and Diastole in Hypertrophic Cardiomyopathy.

scientific article published on March 2016

Impact of a Genetic Risk Score for Coronary Artery Disease on Reducing Cardiovascular Risk: A Pilot Randomized Controlled Study

scientific article published on 14 August 2017

Impact of cardiorespiratory fitness on the obesity paradox in patients with heart failure

scientific article

Impact of the distance from the chest wall to the heart on surface ECG voltage in athletes

scientific article published on 08 March 2020

Improving Reporting of Exercise Capacity Across Age Ranges Using Novel Workload Reference Equations

scholarly article

In Vivo Post-Cardiac Arrest Myocardial Dysfunction Is Supported by Ca2+/Calmodulin-Dependent Protein Kinase II-Mediated Calcium Long-Term Potentiation and Mitigated by Alda-1, an Agonist of Aldehyde Dehydrogenase Type 2

scientific article

In situ optical mapping of voltage and calcium in the heart

scientific article (publication date: 2012)

Incident Atrial Fibrillation Is Associated With MYH7 Sarcomeric Gene Variation in Hypertrophic Cardiomyopathy

article

Incremental value of right heart metrics and exercise performance to well-validated risk scores in dilated cardiomyopathy

scientific article

Informed Consent

scientific article published in March 2017

Insights into human beta-cardiac myosin function from single molecule and single cell studies

scientific article

Interdisciplinary psychosocial care for families with inherited cardiovascular diseases

scientific article published on 28 April 2016

Interpretation of the electrocardiogram of young athletes

scientific article published on 01 August 2011

Interpreting whole-genome sequencing--reply

scientific article published in July 2014

Is Genetic Testing for Heart Disease Right for Me?

scientific article published on 31 July 2019

Is stress cardiomyopathy the underlying cause of ventricular dysfunction associated with brain death?

scientific article published on 8 June 2010

Large Q and S waves in lead III on the electrocardiogram distinguish patients with hypertrophic cardiomyopathy from athletes

scientific article published on 21 April 2018

Latent obstruction and left atrial size are predictors of clinical deterioration leading to septal reduction in hypertrophic cardiomyopathy.

scientific article published on 29 January 2014

Left atrial function and phenotypes in asymmetric hypertrophic cardiomyopathy

scientific article published on April 2017

Limitations of Current AHA Guidelines and Proposal of New Guidelines for the Preparticipation Examination of Athletes

scientific article published on 24 April 2015

Limitations of Electrocardiography for Detecting Left Ventricular Hypertrophy or Concentric Remodeling in Athletes

scientific article published on 15 November 2019

Load-dependent effects of apelin on murine cardiomyocytes

scientific article published on 18 September 2017

Long-read genome sequencing identifies causal structural variation in a Mendelian disease.

scientific article published on 22 June 2017

Long-term outcomes of septal reduction for obstructive hypertrophic cardiomyopathy

scientific article published on 18 September 2014

Loss of function, missense, and intronic variants in NOTCH1 confer different risks for left ventricular outflow tract obstructive heart defects in two European cohorts

scientific article published on 04 December 2018

Low-dose growth hormone is cardioprotective in uremia

scientific article published on 23 July 2008

MEDICATION COMMUNICATION PRACTICES BETWEEN PROVIDERS IN CARDIOLOGY

scholarly article published in March 2018

Magnetic resonance imaging of progressive cardiomyopathic changes in the db/db mouse

scientific article published on 22 November 2006

Matrix metalloproteinase circulating levels, genetic polymorphisms, and susceptibility to acute myocardial infarction among patients with coronary artery disease

scientific article published on 01 December 2007

Measurement precision in the optimization of cardiac resynchronization therapy

scientific article

Mechanisms of exercise intolerance in patients with hypertrophic cardiomyopathy

scientific article published on 16 July 2009

Medical implications of technical accuracy in genome sequencing

scientific article

Medical relevance of protein-truncating variants across 337,205 individuals in the UK Biobank study.

scientific article published on 24 April 2018

Mind the Gap: Current Challenges and Future State of Heart Failure Care

scientific article published on 5 September 2017

Mobile Health Advances in Physical Activity, Fitness, and Atrial Fibrillation: Moving Hearts

scientific article published on 01 June 2018

Molecular Choreography of Acute Exercise

scientific article published on 01 May 2020

Molecular diagnosis of long QT syndrome at 10 days of life by rapid whole genome sequencing

scientific article

Mouse strain-specific differences in vascular wall gene expression and their relationship to vascular disease.

scientific article published on 18 November 2004

Multi-omic profiling reveals widespread dysregulation of innate immunity and hematopoiesis in COVID-19

scientific article

Multi-task deep learning for cardiac rhythm detection in wearable devices

scientific article published on 09 September 2020

Multidimensional structure-function relationships in human β-cardiac myosin from population-scale genetic variation

scientific article

Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy

scientific article published on 27 January 2020

NOVEL ALPHA-ACTININ 2 MUTATIONS ARE ASSOCIATED WITH CARDIOMYOPATHY AND HYPERTROPHY IN HUMAN CARDIAC TISSUE AND IPSC-DERIVED CARDIOMYOCYTES

scholarly article

Navigating Genetic and Phenotypic Uncertainty in Left Ventricular Noncompaction

scientific article published on 01 August 2017

Network analysis of human in-stent restenosis

scientific article published on 04 December 2006

New insights for the diagnosis and management of right ventricular failure, from molecular imaging to targeted right ventricular therapy

scientific article published on March 2010

Next-Generation Sequencing in Cardiovascular Disease: Present Clinical Applications and the Horizon of Precision Medicine.

scientific article published in January 2017

Nitric oxide control of cardiac function: is neuronal nitric oxide synthase a key component?

scientific article

Normal electrocardiographic findings: recognising physiological adaptations in athletes.

scientific article

Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction

scientific article published on 8 September 2003

One is the loneliest number: genotypic matchmaking using the electronic health record

scientific article published on 06 July 2021

Opposing cardiovascular roles for the angiotensin and apelin signaling pathways

scientific article published on 26 September 2006

Orexin: a Missing Link Between Sleep Disorders and Heart Failure?

scientific article published on 18 February 2017

Oxido-reductive regulation of vascular remodeling by receptor tyrosine kinase ROS1.

scientific article

Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure.

scientific article published on 24 June 2019

Pathological Overlap of Arrhythmogenic Right Ventricular Cardiomyopathy and Cardiac Sarcoidosis

scientific article published on 21 September 2019

Pathway analysis of coronary atherosclerosis

scientific article published on 07 June 2005

Patient-Specific Induced Pluripotent Stem Cells Implicate Intrinsic Impaired Contractility in Hypoplastic Left Heart Syndrome

scientific article published on 19 October 2020

Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy.

scientific article

Patterns and prognosis of all components of the J-wave pattern in multiethnic athletes and ambulatory patients

scientific article published on 9 November 2013

Performance comparison of whole-genome sequencing platforms

scientific article

Perioperative cardiac risk: pathophysiology, assessment and management

scientific article published on September 2006

Personal omics profiling reveals dynamic molecular and medical phenotypes

scientific article (publication date: 16 March 2012)

Personalized medicine: hope or hype?

scientific article

Personalized prediction of adverse heart and kidney events using baseline and longitudinal data from SPRINT and ACCORD

scientific article published on 08 August 2019

Personalized preventive medicine: genetics and the response to regular exercise in preventive interventions

scientific article

Pharmacogenetics of heart failure: evidence, opportunities, and challenges for cardiovascular pharmacogenomics

scientific article published on 29 January 2008

Phased whole-genome genetic risk in a family quartet using a major allele reference sequence

scientific article

Physical Activity and Other Health Behaviors in Adults With Hypertrophic Cardiomyopathy ⬇️

scientific article published on January 19, 2013

Physical activity, sleep and cardiovascular health data for 50,000 individuals from the MyHeart Counts Study

article

Physiological Adaptations to Progressive Endurance Exercise Training in Adult And Aged Rats: Insights from The Molecular Transducers of Physical Activity Consortium (MoTrPAC)

scientific article published on 26 March 2024

Plasma concentrations of the novel peptide apelin are decreased in patients with chronic heart failure

scientific article published on 07 February 2006

Predominance of normal left ventricular geometry in the male 'athlete's heart'.

scientific article

Preoperative cardiac evaluation: mechanisms, assessment, and reduction of risk

scientific article

Prevalence and Progression of Late Gadolinium Enhancement in Children and Adolescents With Hypertrophic Cardiomyopathy

scientific article published on 01 August 2018

Prevalence and clinical correlates of right ventricular dysfunction in patients with hypertrophic cardiomyopathy

scientific article published on 4 October 2013

Prevalence and prognostic role of right ventricular involvement in stress-induced cardiomyopathy

scientific article published on 19 February 2015

Prevention of Sudden Cardiac Death With Implantable Cardioverter-Defibrillators in Children and Adolescents With Hypertrophic Cardiomyopathy

article

Prognostic implications of Q waves and T-wave inversion associated with early repolarization

scientific article

Prognostic value of capnography during rest and exercise in patients with heart failure

scientific article published on 26 April 2012

Prognostic value of heart rate increase at onset of exercise testing

scientific article published on 22 January 2007

Progressive Dyspnea After CABG: Complication of Retained Epicardial Pacing Wires

scientific article published in October 2008

Promise of Precision Medicine--Reply

scientific article published in October 2015

Quantitative approaches to variant classification increase the yield and precision of genetic testing in Mendelian diseases: the case of hypertrophic cardiomyopathy

scientific article published on 29 January 2019

RESTING BLOOD PRESSURE IN 2881 ATHLETES AGED 9-35 YEARS OF AGE AND THE RELATION TO SEX, AGE, BODY SIZE, AND AFRO-AMERICAN DESCENT

scholarly article

RNA-Seq identifies novel myocardial gene expression signatures of heart failure

scientific article

Race Differences in Ventricular Remodeling and Function Among College Football Players ⬇️

scientific article published on April 18, 2013

Randomized trial of personal genomics for preventive cardiology: design and challenges

scientific article

Rapid Genome Sequencing in the Critically Ill

scientific article published on 06 March 2019

Rat model of veno-arterial extracorporeal membrane oxygenation.

scientific article published on 07 February 2014

Re: A prospective randomized evaluation of VV delay optimization in CRT-D recipients: echocardiographic observations from the RHYTHM II ICD study

scientific article published on 31 August 2009

Redox regulation of vascular remodeling

scientific article

Regional Variation in RBM20 Causes a Highly Penetrant Arrhythmogenic Cardiomyopathy

scientific article published on 01 March 2019

Report from the Annual Conference of the British Society of Echocardiography, November 2016, Queen Elizabeth II Conference Centre, LondonForewordNational Invited Lecture 2016Echo Research and Practice sessionAbstract 1: Left ventricular mechano-tempo

scientific article published on 01 September 2017

Response by Ho et al to Letter Regarding Article, "Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights From the Sarcomeric Human Cardiomyopathy Registry (SHaRe)"

scientific article published on 01 March 2019

Right Ventricular Structure and Function in the Veteran Ultramarathon Runner: Is There Evidence for Chronic Maladaptation?

scientific article

SARS-CoV-2 RNAaemia predicts clinical deterioration and extrapulmonary complications from COVID-19

scientific article published on 22 December 2020

SARS-CoV-2 RNAemia Predicts Clinical Deterioration and Extrapulmonary Complications from COVID-19

scientific article published in 2022

Sequence to Medical Phenotypes: A Framework for Interpretation of Human Whole Genome DNA Sequence Data

scientific article

Should the exercise ECG be used to screen for sudden cardiac death?

scientific article published on 05 February 2009

Signature patterns of gene expression in mouse atherosclerosis and their correlation to human coronary disease

scientific article published on 03 May 2005

Silencing of MYH7 ameliorates disease phenotypes in human iPSC-Cardiomyocytes

scientific article published on 22 June 2020

Smartphone-Based VO2max Measurement With Heart Snapshot in Clinical and Real-world Settings With a Diverse Population: Validation Study

scientific article published on 4 June 2021

Spatial and Functional Distribution of MYBPC3 Pathogenic Variants and Clinical Outcomes in Patients with Hypertrophic Cardiomyopathy

scientific article published on 25 August 2020

Sports genetics moving forward: lessons learned from medical research

scientific article

Stable, covalent attachment of laminin to microposts improves the contractility of mouse neonatal cardiomyocytes.

scientific article

Statin use and ventricular arrhythmias during clinical treadmill testing

scientific article published on 3 September 2008

Stretch-Induced Biased Signaling in Angiotensin II Type 1 and Apelin Receptors for the Mediation of Cardiac Contractility and Hypertrophy

scientific article published on 13 March 2020

Systematic Comparison of Digital Electrocardiograms From Healthy Athletes and Patients With Hypertrophic Cardiomyopathy

scientific article published in June 2015

Systems Genomics Identifies a Key Role for Hypocretin/Orexin Receptor-2 in Human Heart Failure

scientific article

Systems biology of heart failure, challenges and hopes ⬇️

scientific article published on July 1, 2011

Systems-based approaches to cardiovascular biomarker discovery ⬇️

scientific article published on June 1, 2012

Taming Rare Variation With Known Biology in Long QT Syndrome ⬇️

scientific article published on June 1, 2013

Taming the genome: towards better genetic test interpretation

scientific article published on 20 June 2016

Targeted Long-Read RNA Sequencing Demonstrates Transcriptional Diversity Driven by Splice-Site Variation in MYBPC3

scientific article published on 01 May 2019

Targeting ferroptosis: A novel therapeutic strategy for the treatment of mitochondrial disease-related epilepsy

article

Telomere shortening is a hallmark of genetic cardiomyopathies

article published in the Proceedings of the National Academy of Sciences of the United States of America

Temporal Trend of Age at Diagnosis in Hypertrophic Cardiomyopathy: An Analysis of the International Sarcomeric Human Cardiomyopathy Registry

scientific article published on 08 September 2020

The Future of Genomic Research in Athletic Performance and Adaptation to Training

scientific article published on 10 June 2016

The Impact of ST Elevation on Athletic Screening ⬇️

scientific article published on September 1, 2011

The Medical Genome Initiative: moving whole-genome sequencing for rare disease diagnosis to the clinic

scientific article published on 27 May 2020

The Undiagnosed Diseases Network of the National Institutes of Health: A National Extension

scientific article

The Undiagnosed Diseases Network: Accelerating Discovery about Health and Disease

scientific article

The Undiagnosed Diseases Program--Reply

scientific article published in May 2016

The concept of ventricular reserve in heart failure and pulmonary hypertension: an old metric that brings us one step closer in our quest for prediction ⬇️

scientific article published on March 1, 2011

The effect of digital physical activity interventions on daily step count: a randomised controlled crossover substudy of the MyHeart Counts Cardiovascular Health Study

scientific article published on 09 October 2019

The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo

scientific article

The impact of chronic endurance and resistance training upon the right ventricular phenotype in male athletes.

scientific article published on 17 March 2015

The medical device safety act of 2009: clarifying preemption

scientific article published on 01 November 2009

The precision medicine initiative: a new national effort

scientific article

The prognostic significance of heart rate recovery is not dependent upon maximal effort in patients with heart failure

scientific article

The prognostic utility of cardiopulmonary exercise testing stands the test of time in patients with heart failure

scientific article published in July 2012

The prognostic value of early repolarization with ST-segment elevation in African Americans ⬇️

scientific article published on November 15, 2011

The relationship between minute ventilation and oxygen consumption in heart failure: Comparing peak VE/VO2 and the oxygen uptake efficiency slope

The right ventricle following ultra-endurance exercise: insights from novel echocardiography and 12-lead electrocardiography.

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Time based versus strain based myocardial performance indices in hypertrophic cardiomyopathy, the merging role of left atrial strain

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Transcriptional profiling of in vitro smooth muscle cell differentiation identifies specific patterns of gene and pathway activation

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Unexplained double-chambered left ventricle associated with contracting right ventricular aneurysm and right atrial enlargement

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Upregulation of the apelin-APJ pathway promotes neointima formation in the carotid ligation model in mouse

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Using "big data" to dissect clinical heterogeneity

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Validation of a cardiopulmonary exercise test score in heart failure

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Value of Strain Imaging and Maximal Oxygen Consumption in Patients With Hypertrophic Cardiomyopathy

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Ventricular arrhythmias during clinical treadmill testing and prognosis

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Video-based AI for beat-to-beat assessment of cardiac function

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Weakly supervised classification of aortic valve malformations using unlabeled cardiac MRI sequences

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What's in a Name? Factors That Influence the Usage of Generic Versus Trade Names for Cardiac Medications Among Healthcare Providers

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Whole-exome sequencing reveals TopBP1 as a novel gene in idiopathic pulmonary arterial hypertension

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Yield of whole exome sequencing in undiagnosed patients facing insurance coverage barriers to genetic testing

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