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List of works by Olaf Wolkenhauer

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Systems medicine and integrated care to combat chronic noncommunicable diseases

scientific article
Do simple models lead to generality in ecology?

scientific article published in July 2013
Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease

scientific article
Regulation of cell cycle checkpoint kinase WEE1 by miR-195 in malignant melanoma

scientific article
COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms

scientific article published on 05 May 2020
Understanding microRNA-mediated gene regulatory networks through mathematical modelling.

scientific article published on 17 June 2016
MicroRNA–mRNA interactions in colorectal cancer and their role in tumor progression

scientific article published on March 1, 2015
Minimum Information About a Simulation Experiment (MIASE)

scientific article
miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy.

scientific article
Computational analysis of target hub gene repression regulated by multiple and cooperative miRNAs

scientific article published on 13 July 2012
The road from systems biology to systems medicine

scientific article published on 11 January 2013
Investigations into the analysis and modeling of the TNF alpha-mediated NF-kappa B-signaling pathway

scientific article
E2F1 induces miR‐224/452 expression to drive EMT through TXNIP downregulation

scientific article published on October 23, 2014
Gene Expression in Low- and High-Dose-Irradiated Human Peripheral Blood Lymphocytes: Possible Applications for Biodosimetry

article
Modeling and simulation of intracellular dynamics: choosing an appropriate framework

scientific article
Analysing the impact of nucleo-cytoplasmic shuttling of β-catenin and its antagonists APC, Axin and GSK3 on Wnt/β-catenin signalling

scientific article published on 17 July 2013
Enabling multiscale modeling in systems medicine

scientific article
Cooperative gene regulation by microRNA pairs and their identification using a computational workflow

scientific article published on May 29, 2014
MicroRNA-Regulated Networks: The Perfect Storm for Classical Molecular Biology, the Ideal Scenario for Systems Biology

scientific article published on January 1, 2013
Feedback dynamics and cell function: Why systems biology is called Systems Biology

scientific article published on 8 April 2005
Systems biology of JAK-STAT signalling in human malignancies

scientific article published on 06 July 2011
MicroRNA and Transcription Factor Gene Regulatory Network Analysis Reveals Key Regulatory Elements Associated with Prostate Cancer Progression

scientific article
Switching feedback mechanisms realize the dual role of MCIP in the regulation of calcineurin activity.

scientific article published on 5 October 2006
Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures

scientific article
Kinetic modeling-based detection of genetic signatures that provide chemoresistance via the E2F1-p73/DNp73-miR-205 network

scientific article published on 27 February 2013
A frequency-based gene selection method to identify robust biomarkers for radiation dose prediction

scientific article published in March 2012
Optimal sampling time selection for parameter estimation in dynamic pathway modeling

scientific article published in July 2004
Dynamics of biological systems: role of systems biology in medical research

scientific article published on November 2006
A systems biology approach to investigate the effect of pH-induced gene regulation on solvent production by Clostridium acetobutylicum in continuous culture

scientific article (publication date: 19 January 2011)
The systems biology of mitochondrial fission and fusion and implications for disease and aging

scientific article published on February 2014
Clinico-pathologic function of cerebral ABC transporters - implications for the pathogenesis of Alzheimer's disease

scientific article published on August 2008
The dynamic systems approach to control and regulation of intracellular networks

scientific article
Why model?

scientific article published on January 28, 2014
The multikinase inhibitor Sorafenib displays significant antiproliferative effects and induces apoptosis via caspase 3, 7 and PARP in B- and T-lymphoblastic cells

scientific article published on 15 October 2010
Association of RHAMM with E2F1 promotes tumour cell extravasation by transcriptional up-regulation of fibronectin

scientific article
Mathematical modelling of interferon-gamma signalling in pancreatic stellate cells reflects and predicts the dynamics of STAT1 pathway activity

scientific article published on 23 September 2009
Approximations and their consequences for dynamic modelling of signal transduction pathways

scientific article published on 24 August 2006
The search for organizing principles as a cure against reductionism in systems medicine

scientific article published on May 24, 2013
Diagnostic Potential of Imaging Flow Cytometry.

scientific article published on 30 January 2018
Studies on mechanisms of interferon-gamma action in pancreatic cancer using a data-driven and model-based approach

scientific article
How Modeling Standards, Software, and Initiatives Support Reproducibility in Systems Biology and Systems Medicine

scientific article published on 02 June 2016
Integrative modelling of pH-dependent enzyme activity and transcriptomic regulation of the acetone-butanol-ethanol fermentation of Clostridium acetobutylicum in continuous culture

scientific article
MiR-205-5p and miR-342-3p cooperate in the repression of the E2F1 transcription factor in the context of anticancer chemotherapy resistance.

scientific article published in January 2018
Systems biology to battle vascular disease

scientific article published on 03 February 2010
Investigating the two-moment characterisation of subcellular biochemical networks

scientific article published on 3 June 2009
Glucose de-repression by yeast AMP-activated protein kinase SNF1 is controlled via at least two independent steps

scientific article published on 4 March 2014
Systems biologists seek fuller integration of systems biology approaches in new cancer research programs

scientific article
2-DE profiling of GDNF overexpression-related proteome changes in differentiating ST14A rat progenitor cells

scientific article published in January 2007
Non-coding RNA detection methods combined to improve usability, reproducibility and precision

scientific article
Improving the reuse of computational models through version control

scientific article published on 18 January 2013

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